Translational pausing ensures membrane targeting and cytoplasmic splicing of XBP1u mRNA

Science

Volumn 331, Issue 6017, 2011, Pages 586-589

  Yanagitani, Kota ^a   Kimata, Yukio ^a   Kadokura, Hiroshi ^a   Kohno, Kenji ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; X BOX BINDING PROTEIN 1;

CYTOLOGY; CYTOPLASM; ENZYME ACTIVITY; MEMBRANE; MITOCHONDRIAL DNA; PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MAMMAL CELL; MUTATIONAL ANALYSIS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN TRANSPORT; REGULATORY MECHANISM; RIBOSOME; RNA SPLICING; RNA TRANSLATION;

CELL LINE; CYTOPLASM; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INTRACELLULAR MEMBRANES; PROTEIN BIOSYNTHESIS; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; RIBOSOMES; RNA SPLICING; RNA, MESSENGER; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 79551629027     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1197142     Document Type: Article

References (10)

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10. We thank J. Iida-Hashimoto and N. Fujimoto for technical assistance and K. Ito, S. Chiba, and H. Yoshida for discussions. This work was supported by Grants-in-Aid for Scientific Research on Priority Areas (K.K., Y.K.) and Scientific Research B (K.K.) of KAKENHI from the Ministry of Education, Culture, Sports, Science and Technology of Japan. K.Y. is a special postdoctoral fellow supported by Global Center of Excellence program from the Japan Society for the Promotion of Science.