-
2
-
-
0029751950
-
A reaction-diffusion model of cancer invasion
-
Gatenby RA, Gawlinski ET. A reaction-diffusion model of cancer invasion. Cancer Res. 1996;56:5745-5753.
-
(1996)
Cancer Res
, vol.56
, pp. 5745-5753
-
-
Gatenby, R.A.1
Gawlinski, E.T.2
-
3
-
-
0025875633
-
Population ecology issues in tumor growth
-
Gatenby RA. Population ecology issues in tumor growth. Cancer Res. 1991;51:2542-2547.
-
(1991)
Cancer Res
, vol.51
, pp. 2542-2547
-
-
Gatenby, R.A.1
-
4
-
-
37549013776
-
A microenvironmental model of carcinogenesis
-
In press
-
Gatenby RA, Gillies RJ. A microenvironmental model of carcinogenesis. Nat Rev Cancer. 2008. In press.
-
(2008)
Nat Rev Cancer
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
5
-
-
33847307576
-
Information theory in living systems, methods, applications, and challenges
-
Gatenby RA, Frieden BR. Information theory in living systems, methods, applications, and challenges. Bull Math Biol. 2007;69:635-657.
-
(2007)
Bull Math Biol
, vol.69
, pp. 635-657
-
-
Gatenby, R.A.1
Frieden, B.R.2
-
7
-
-
0141988694
-
An evolutionary model of carcinogenesis
-
Gatenby RA, Vincent TL. An evolutionary model of carcinogenesis. Cancer Res. 2003;63:6212-6220.
-
(2003)
Cancer Res
, vol.63
, pp. 6212-6220
-
-
Gatenby, R.A.1
Vincent, T.L.2
-
8
-
-
0642349133
-
Application of quantitative models from population biology and evolutionary game theory to tumor therapeutic strategies
-
Gatenby RA, Vincent TL. Application of quantitative models from population biology and evolutionary game theory to tumor therapeutic strategies. Mol Cancer Ther. 2003;2:919-927.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 919-927
-
-
Gatenby, R.A.1
Vincent, T.L.2
-
9
-
-
0036645517
-
Application of information theory and extreme physical information to carcinogenesis
-
Gatenby RA, Frieden BR. Application of information theory and extreme physical information to carcinogenesis. Cancer Res. 2002;62:3675-3684.
-
(2002)
Cancer Res
, vol.62
, pp. 3675-3684
-
-
Gatenby, R.A.1
Frieden, B.R.2
-
11
-
-
0035233633
-
Mathematical models of tumour invasion mediated by transformation-induced alteration of microenvironmental pH
-
Gatenby RA, Gawlinski ET. Mathematical models of tumour invasion mediated by transformation-induced alteration of microenvironmental pH. Novartis Found Symp. 2001;240:85-96.
-
(2001)
Novartis Found Symp
, vol.240
, pp. 85-96
-
-
Gatenby, R.A.1
Gawlinski, E.T.2
-
12
-
-
0030124081
-
Application of competition theory to tumour growth: Implications for tumour biology and treatment
-
Gatenby RA. Application of competition theory to tumour growth: implications for tumour biology and treatment. Eur J Cancer. 1996;32A:722-726.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 722-726
-
-
Gatenby, R.A.1
-
13
-
-
0038236716
-
The basement membrane matrix in malignancy
-
Engbring JA, Kleinman HK. The basement membrane matrix in malignancy. J Pathol. 2003;200:465-470.
-
(2003)
J Pathol
, vol.200
, pp. 465-470
-
-
Engbring, J.A.1
Kleinman, H.K.2
-
14
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest. 2003;112:1776-1784.
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
15
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang J, Mani SA, Donaher JL, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell. 2004;117:927-939.
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
-
16
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
17
-
-
34548317034
-
Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer
-
Gatenby RA, Smallbone K, Maini PK, et al. Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer. Br J Cancer. 2007;97:646-653.
-
(2007)
Br J Cancer
, vol.97
, pp. 646-653
-
-
Gatenby, R.A.1
Smallbone, K.2
Maini, P.K.3
-
18
-
-
0032832051
-
Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites
-
Melendez-Colon VJ, Luch A, Seidel A, Baird WM. Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites. Carcinogenesis. 1999;20:1885-1891.
-
(1999)
Carcinogenesis
, vol.20
, pp. 1885-1891
-
-
Melendez-Colon, V.J.1
Luch, A.2
Seidel, A.3
Baird, W.M.4
-
19
-
-
0018461031
-
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src)
-
Oppermann H, Levinson AD, Varmus HE, Levintow L, Bishop JM. Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src). Proc Natl Acad Sci USA. 1979;76:1804-1808.
-
(1979)
Proc Natl Acad Sci USA
, vol.76
, pp. 1804-1808
-
-
Oppermann, H.1
Levinson, A.D.2
Varmus, H.E.3
Levintow, L.4
Bishop, J.M.5
-
20
-
-
0024425887
-
Checkpoints: Controls that ensure the order of cell cycle events
-
Hartwell LH, Weinert TA. Checkpoints: controls that ensure the order of cell cycle events. Science. 1989;243:629-634.
-
(1989)
Science
, vol.243
, pp. 629-634
-
-
Hartwell, L.H.1
Weinert, T.A.2
-
21
-
-
0033013985
-
Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts
-
Vaziri H, Squire JA, Pandita TK, et al. Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts. Mol Cell Biol. 1999;19:2373-2379.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2373-2379
-
-
Vaziri, H.1
Squire, J.A.2
Pandita, T.K.3
-
22
-
-
16444374716
-
Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer
-
Pan H, Califano J, Ponte JF, et al. Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer. Cancer Res. 2005;65:1664-1669.
-
(2005)
Cancer Res
, vol.65
, pp. 1664-1669
-
-
Pan, H.1
Califano, J.2
Ponte, J.F.3
-
23
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61:759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
24
-
-
38349103951
-
Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation
-
Li Z, Zhao J, Du Y, et al. Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation. Proc Natl Acad Sci USA. 2008;105:162-167.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 162-167
-
-
Li, Z.1
Zhao, J.2
Du, Y.3
-
26
-
-
0035105565
-
Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast
-
Wykoff CC, Beasley N, Watson PH, et al. Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast. Am J Pathol. 2001;158:1011-1019.
-
(2001)
Am J Pathol
, vol.158
, pp. 1011-1019
-
-
Wykoff, C.C.1
Beasley, N.2
Watson, P.H.3
-
27
-
-
34548317034
-
Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer
-
Gatenby RA, Smallbone K, Maini PK, et al. Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer. Br J Cancer. 2007;97:646-653.
-
(2007)
Br J Cancer
, vol.97
, pp. 646-653
-
-
Gatenby, R.A.1
Smallbone, K.2
Maini, P.K.3
-
28
-
-
0032788570
-
Acidic environment causes apoptosis by increasing caspase activity
-
Park HJ, Lyons JC, Ohtsubo T, Song CW. Acidic environment causes apoptosis by increasing caspase activity. Br J Cancer. 1999;80:1892-1897.
-
(1999)
Br J Cancer
, vol.80
, pp. 1892-1897
-
-
Park, H.J.1
Lyons, J.C.2
Ohtsubo, T.3
Song, C.W.4
-
29
-
-
0033609365
-
An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: Implications for clonal selection during colorectal carcinogenesis
-
Williams AC, Collard TJ, Paraskeva C. An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: implications for clonal selection during colorectal carcinogenesis. Oncogene. 1999;18:3199-3204.
-
(1999)
Oncogene
, vol.18
, pp. 3199-3204
-
-
Williams, A.C.1
Collard, T.J.2
Paraskeva, C.3
-
30
-
-
0034021690
-
Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
-
Semenza GL. Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit Rev Biochem Mol Biol. 2000;35:71-103.
-
(2000)
Crit Rev Biochem Mol Biol
, vol.35
, pp. 71-103
-
-
Semenza, G.L.1
-
31
-
-
0030864485
-
Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions
-
Kim CY, Tsai MH, Osmanian C, et al. Selection of human cervical epithelial cells that possess reduced apoptotic potential to low-oxygen conditions. Cancer Res. 1997;57:4200-4204.
-
(1997)
Cancer Res
, vol.57
, pp. 4200-4204
-
-
Kim, C.Y.1
Tsai, M.H.2
Osmanian, C.3
-
32
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber TG, Osmanian C, Jacks T, et al. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature. 1996;379:88-91.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
-
33
-
-
33846331592
-
-
Abbey CK, Borowsky AD, Gregg JP, Cardiff RD, Cherry SR. Preclinical imaging of mammary intraepithelial neoplasia with positron emission tomography. J Mammary Gland Biol Neoplasia. 2006;11:137-149.
-
Abbey CK, Borowsky AD, Gregg JP, Cardiff RD, Cherry SR. Preclinical imaging of mammary intraepithelial neoplasia with positron emission tomography. J Mammary Gland Biol Neoplasia. 2006;11:137-149.
-
-
-
-
37
-
-
3042692979
-
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion
-
Bourguignon LY, Singleton PA, Diedrich F, Stern R, Gilad E. CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion. J Biol Chem. 2004;279:26991-27007.
-
(2004)
J Biol Chem
, vol.279
, pp. 26991-27007
-
-
Bourguignon, L.Y.1
Singleton, P.A.2
Diedrich, F.3
Stern, R.4
Gilad, E.5
-
38
-
-
0033129693
-
Association of hyaluronidase and breast adenocarcinoma invasiveness
-
Madan AK, Yu K, Dhurandhar N, Cullinane C, Pang Y, Beech DJ. Association of hyaluronidase and breast adenocarcinoma invasiveness. Oncol Rep. 1999;6:607-609.
-
(1999)
Oncol Rep
, vol.6
, pp. 607-609
-
-
Madan, A.K.1
Yu, K.2
Dhurandhar, N.3
Cullinane, C.4
Pang, Y.5
Beech, D.J.6
-
39
-
-
0028618307
-
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells
-
Rozhin J, Sameni M, Ziegler G, Sloane BF. Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. Cancer Res. 1994;54:6517-6525.
-
(1994)
Cancer Res
, vol.54
, pp. 6517-6525
-
-
Rozhin, J.1
Sameni, M.2
Ziegler, G.3
Sloane, B.F.4
-
40
-
-
0027930711
-
Characterization of very acidic phagosomes in breast cancer cells and their association with invasion
-
Montcourrier P, Mangeat PH, Valembois C, et al. Characterization of very acidic phagosomes in breast cancer cells and their association with invasion. J Cell Sci. 1994;107:2381-2391.
-
(1994)
J Cell Sci
, vol.107
, pp. 2381-2391
-
-
Montcourrier, P.1
Mangeat, P.H.2
Valembois, C.3
-
41
-
-
33746149756
-
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
-
Rofstad EK, Mathiesen B, Kindem K, Galappathi K. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res. 2006;66:6699-6707.
-
(2006)
Cancer Res
, vol.66
, pp. 6699-6707
-
-
Rofstad, E.K.1
Mathiesen, B.2
Kindem, K.3
Galappathi, K.4
-
42
-
-
0025771024
-
Glucose starvation and acidosis: Effect on experimental metastasic potential, DNA content and MTX resistance of murine tumour cells
-
Schlappack OK, Zimmermann A, Hill RP. Glucose starvation and acidosis: effect on experimental metastasic potential, DNA content and MTX resistance of murine tumour cells. Br J Cancer. 1991;64:663-670.
-
(1991)
Br J Cancer
, vol.64
, pp. 663-670
-
-
Schlappack, O.K.1
Zimmermann, A.2
Hill, R.P.3
-
43
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest. 2003;112:1776-1784.
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
44
-
-
34250703744
-
Vimentin and epithelial-mesenchymal transition in human breast cancer: Observations in vitro and in vivo
-
Kokkinos MI, Wafai R, Wong MK, Newgreen DF, Thompson EW, Waltham M. Vimentin and epithelial-mesenchymal transition in human breast cancer: observations in vitro and in vivo. Cells Tissues Organs. 2007;185:191-203.
-
(2007)
Cells Tissues Organs
, vol.185
, pp. 191-203
-
-
Kokkinos, M.I.1
Wafai, R.2
Wong, M.K.3
Newgreen, D.F.4
Thompson, E.W.5
Waltham, M.6
-
45
-
-
27844461512
-
Epithelial-mesenchymal transition in development and cancer: Role of phosphatidylinositol 3′ kinase/AKT pathways
-
Larue L, Bellacosa A. Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways. Oncogene. 2005;24:7443-7454.
-
(2005)
Oncogene
, vol.24
, pp. 7443-7454
-
-
Larue, L.1
Bellacosa, A.2
-
46
-
-
34247197835
-
Active versus passive mechanisms in metastasis: Do cancer cells crawl into vessels, or are they pushed?
-
Bockhorn M, Jain RK, Munn LL. Active versus passive mechanisms in metastasis: do cancer cells crawl into vessels, or are they pushed? Lancet Oncol. 2007;8:444-448.
-
(2007)
Lancet Oncol
, vol.8
, pp. 444-448
-
-
Bockhorn, M.1
Jain, R.K.2
Munn, L.L.3
-
47
-
-
50549121134
-
The distribution of secondary growths in cancer of the breast
-
Paget S. The distribution of secondary growths in cancer of the breast. Lancet. 1889;133:571-573.
-
(1889)
Lancet
, vol.133
, pp. 571-573
-
-
Paget, S.1
-
48
-
-
35148899178
-
Destemming cancer stem cells
-
Hill RP, Perris R. "Destemming" cancer stem cells. J Natl Cancer Inst. 2007;99:1435-1440.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1435-1440
-
-
Hill, R.P.1
Perris, R.2
-
49
-
-
0026083903
-
Tumor angiogenesis and metastasis: Correlation in invasive breast carcinoma
-
Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med. 1991;324:1-8.
-
(1991)
N Engl J Med
, vol.324
, pp. 1-8
-
-
Weidner, N.1
Semple, J.P.2
Welch, W.R.3
Folkman, J.4
-
50
-
-
33744942376
-
Acid-mediated tumor invasion: A multidisciplinary study
-
Gatenby RA, Gawlinski ET, Gmitro AF, Kaylor B, Gillies RJ. Acid-mediated tumor invasion: a multidisciplinary study. Cancer Res. 2006;66:5216-5223.
-
(2006)
Cancer Res
, vol.66
, pp. 5216-5223
-
-
Gatenby, R.A.1
Gawlinski, E.T.2
Gmitro, A.F.3
Kaylor, B.4
Gillies, R.J.5
-
51
-
-
0035021707
-
A tabulated summary of the FDG PET literature
-
Gambhir SS, Czernin J, Schwimmer J, Silverman DH, Coleman RE, Phelps ME. A tabulated summary of the FDG PET literature. J Nucl Med. 2001;42(5, suppl):1S-93S.
-
(2001)
J Nucl Med
, vol.42
, Issue.5 and SUPPL.
-
-
Gambhir, S.S.1
Czernin, J.2
Schwimmer, J.3
Silverman, D.H.4
Coleman, R.E.5
Phelps, M.E.6
-
52
-
-
20244376908
-
Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development
-
Kelloff GJ, Hoffman JM, Johnson B, et al. Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development. Clin Cancer Res. 2005;11:2785-2808.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2785-2808
-
-
Kelloff, G.J.1
Hoffman, J.M.2
Johnson, B.3
-
53
-
-
0035708631
-
From tumor biology to clinical Pet: A review of positron emission tomography (PET) in oncology
-
Kubota K. From tumor biology to clinical Pet: a review of positron emission tomography (PET) in oncology. Ann Nucl Med. 2001;15:471-486.
-
(2001)
Ann Nucl Med
, vol.15
, pp. 471-486
-
-
Kubota, K.1
-
54
-
-
0015453103
-
The Pasteur effect and the relations between respiration and fermentation
-
Krebs HA. The Pasteur effect and the relations between respiration and fermentation. Essays Biochem. 1972;8:1-34.
-
(1972)
Essays Biochem
, vol.8
, pp. 1-34
-
-
Krebs, H.A.1
-
55
-
-
46749088102
-
Limiting factors in glycolysis of ascites tumour cells and the pasteur effect
-
Racker E, Wu R. Limiting factors in glycolysis of ascites tumour cells and the pasteur effect. Regulation of Cell Metabolism. 1958;205-229.
-
(1958)
Regulation of Cell Metabolism
, pp. 205-229
-
-
Racker, E.1
Wu, R.2
-
56
-
-
0342430486
-
Regulatory mechanisms in carbohydrate metabolism. IV. Pasteur effect and crabtree effect in ascites tumor cells
-
Wu R, Racker E. Regulatory mechanisms in carbohydrate metabolism. IV. Pasteur effect and crabtree effect in ascites tumor cells. J Biol Chem. 1959;234:1036-1041.
-
(1959)
J Biol Chem
, vol.234
, pp. 1036-1041
-
-
Wu, R.1
Racker, E.2
-
57
-
-
13944273440
-
Imaging hypoxia and angiogenesis in tumors
-
Rajendran JG, Krohn KA. Imaging hypoxia and angiogenesis in tumors. Radiol Clin North Am. 2005;43:169-187.
-
(2005)
Radiol Clin North Am
, vol.43
, pp. 169-187
-
-
Rajendran, J.G.1
Krohn, K.A.2
-
60
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
61
-
-
20244376908
-
Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development
-
Kelloff GJ, Hoffman JM, Johnson B, et al. Progress and promise of FDG-PET imaging for cancer patient management and oncologic drug development. Clin Cancer Res. 2005;11:2785-2808.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2785-2808
-
-
Kelloff, G.J.1
Hoffman, J.M.2
Johnson, B.3
-
62
-
-
0035479076
-
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer
-
Brizel DM, Schroeder T, Scher RL, et al. Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2001;51:349-353.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.51
, pp. 349-353
-
-
Brizel, D.M.1
Schroeder, T.2
Scher, R.L.3
-
63
-
-
0034652620
-
High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers
-
Walenta S, Wetterling M, Lehrke M, et al. High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers. Cancer Res. 2000;60:916-921.
-
(2000)
Cancer Res
, vol.60
, pp. 916-921
-
-
Walenta, S.1
Wetterling, M.2
Lehrke, M.3
-
64
-
-
34247860855
-
Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/ mass spectrometry
-
Mikuriya K, Kuramitsu Y, Ryozawa S, et al. Expression of glycolytic enzymes is increased in pancreatic cancerous tissues as evidenced by proteomic profiling by two-dimensional electrophoresis and liquid chromatography-mass spectrometry/ mass spectrometry. Int J Oncol. 2007;30:849-855.
-
(2007)
Int J Oncol
, vol.30
, pp. 849-855
-
-
Mikuriya, K.1
Kuramitsu, Y.2
Ryozawa, S.3
-
65
-
-
7944226627
-
Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes
-
Altenberg B, Greulich KO, Altenberg B, Greulich KO. Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes. Genomics. 2004;84:1014-1020.
-
(2004)
Genomics
, vol.84
, pp. 1014-1020
-
-
Altenberg, B.1
Greulich, K.O.2
Altenberg, B.3
Greulich, K.O.4
-
67
-
-
0037080449
-
18fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography
-
18fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography. J Clin Oncol. 2002;20:379-387.
-
(2002)
J Clin Oncol
, vol.20
, pp. 379-387
-
-
Bos, R.1
van Der Hoeven, J.J.2
van der Wall, E.3
-
68
-
-
19644398382
-
18F-FDG distribution with regional expression of glucose transporters and hexokinase-II in experimental tumor
-
18F-FDG distribution with regional expression of glucose transporters and hexokinase-II in experimental tumor. J Nucl Med. 2005;46:675-682.
-
(2005)
J Nucl Med
, vol.46
, pp. 675-682
-
-
Zhao, S.1
Kuge, Y.2
Mochizuki, T.3
-
69
-
-
0035093491
-
Coregulation of glucose uptake and vascular endothelial growth factor (VEGF) in two small-cell lung cancer (SCLC) sublines in vivo and in vitro
-
Pedersen MW, Holm S, Lund EL, Hojgaard L, Kristjansen PE. Coregulation of glucose uptake and vascular endothelial growth factor (VEGF) in two small-cell lung cancer (SCLC) sublines in vivo and in vitro. Neoplasia. 2001;3:80-87.
-
(2001)
Neoplasia
, vol.3
, pp. 80-87
-
-
Pedersen, M.W.1
Holm, S.2
Lund, E.L.3
Hojgaard, L.4
Kristjansen, P.E.5
-
70
-
-
0141857820
-
Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer
-
Rivenzon-Segal D, Boldin-Adamsky S, Seger D, Seger R, Degani H. Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer. Int J Cancer. 2003;107:177-182.
-
(2003)
Int J Cancer
, vol.107
, pp. 177-182
-
-
Rivenzon-Segal, D.1
Boldin-Adamsky, S.2
Seger, D.3
Seger, R.4
Degani, H.5
-
71
-
-
0036077547
-
Glucose transporters: Expression, regulation and cancer
-
Medina RA, Owen GI. Glucose transporters: expression, regulation and cancer. Biol Res. 2002;35:9-26.
-
(2002)
Biol Res
, vol.35
, pp. 9-26
-
-
Medina, R.A.1
Owen, G.I.2
-
72
-
-
19644398382
-
18F-FDG distribution with regional expression of glucose transporters and hexokinase-II in experimental tumor
-
18F-FDG distribution with regional expression of glucose transporters and hexokinase-II in experimental tumor. J Nucl Med. 2005;46:675-682.
-
(2005)
J Nucl Med
, vol.46
, pp. 675-682
-
-
Zhao, S.1
Kuge, Y.2
Mochizuki, T.3
-
73
-
-
33644864991
-
Control of Glut1 promoter activity under basal conditions and in response to hyperosmolarity: Role of Sp1
-
Hwang DY, Ismail-Beigi F. Control of Glut1 promoter activity under basal conditions and in response to hyperosmolarity: role of Sp1. Am J Physiol Cell Physiol. 2006;290:C337-C344.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Hwang, D.Y.1
Ismail-Beigi, F.2
-
74
-
-
36849066369
-
Regulation of GLUT3 and glucose uptake by the cAMP signalling pathway in the breast cancer cell line ZR-75
-
Meneses AM, Medina RA, Kato S, et al. Regulation of GLUT3 and glucose uptake by the cAMP signalling pathway in the breast cancer cell line ZR-75. J Cell Physiol. 2008;214:110-116.
-
(2008)
J Cell Physiol
, vol.214
, pp. 110-116
-
-
Meneses, A.M.1
Medina, R.A.2
Kato, S.3
-
75
-
-
0031577174
-
Insulin-like growth factor I induces tumor hexokinase RNA expression in cancer cells
-
Sebastian S, Kenkare UW. Insulin-like growth factor I induces tumor hexokinase RNA expression in cancer cells. Biochem Biophys Res Commun. 1997;235:389-393.
-
(1997)
Biochem Biophys Res Commun
, vol.235
, pp. 389-393
-
-
Sebastian, S.1
Kenkare, U.W.2
-
76
-
-
0029937409
-
Glucose catabolism in cancer cells: Regulation of the Type II hexokinase promoter by glucose and cyclic AMP
-
Rempel A, Mathupala SP, Perdersen PL. Glucose catabolism in cancer cells: regulation of the Type II hexokinase promoter by glucose and cyclic AMP. FEBS Lett. 1996;385:233-237.
-
(1996)
FEBS Lett
, vol.385
, pp. 233-237
-
-
Rempel, A.1
Mathupala, S.P.2
Perdersen, P.L.3
-
77
-
-
33847655286
-
-
Rho M, Kim J, Jee CD, et al. Expression of type 2 hexokinase and mitochondria-related genes in gastric carcinoma tissues and cell lines. Anticancer Res. 2007;27 (1A):251-258.
-
Rho M, Kim J, Jee CD, et al. Expression of type 2 hexokinase and mitochondria-related genes in gastric carcinoma tissues and cell lines. Anticancer Res. 2007;27 (1A):251-258.
-
-
-
-
78
-
-
0035900767
-
Glucose catabolism in cancer cells: Identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions
-
Mathupala SP, Rempel A, Pedersen PL. Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions. J Biol Chem. 2001;276:43407-43412.
-
(2001)
J Biol Chem
, vol.276
, pp. 43407-43412
-
-
Mathupala, S.P.1
Rempel, A.2
Pedersen, P.L.3
-
79
-
-
0033585463
-
Hexokinase type II: A novel tumor-specific promoter for gene-targeted therapy differentially expressed and regulated in human cancer cells
-
Katabi MM, Chan HL, Karp SE, Batist G. Hexokinase type II: a novel tumor-specific promoter for gene-targeted therapy differentially expressed and regulated in human cancer cells. Hum Gene Ther. 1999;10:155-164.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 155-164
-
-
Katabi, M.M.1
Chan, H.L.2
Karp, S.E.3
Batist, G.4
-
80
-
-
0033840399
-
Identification and characterization of hexokinase isozyme predominantly expressed in malignant tumor cells
-
Shinohara Y. Identification and characterization of hexokinase isozyme predominantly expressed in malignant tumor cells. Yakugaku Zasshi. 2000;120:657-666.
-
(2000)
Yakugaku Zasshi
, vol.120
, pp. 657-666
-
-
Shinohara, Y.1
-
81
-
-
0032545759
-
Clotrimazole and bifonazole detach hexokinase from mitochondria of melanoma cells
-
Penso J, Beitner R. Clotrimazole and bifonazole detach hexokinase from mitochondria of melanoma cells. Eur J Pharmacol. 1998;342:113-117.
-
(1998)
Eur J Pharmacol
, vol.342
, pp. 113-117
-
-
Penso, J.1
Beitner, R.2
-
83
-
-
33746906633
-
Mitochondria in cancer
-
Kroemer G. Mitochondria in cancer. Oncogene. 2006;25:4630-4632.
-
(2006)
Oncogene
, vol.25
, pp. 4630-4632
-
-
Kroemer, G.1
-
84
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science. 1956;123:309-314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
85
-
-
35148889082
-
Loss of the mitochondrial bioenergetic capacity underlies the glucose avidity of carcinomas
-
Lopez-Rios F, Sanchez-Arago M, Garcia-Garcia E, et al. Loss of the mitochondrial bioenergetic capacity underlies the glucose avidity of carcinomas. Cancer Res. 2007;67:9013-9017.
-
(2007)
Cancer Res
, vol.67
, pp. 9013-9017
-
-
Lopez-Rios, F.1
Sanchez-Arago, M.2
Garcia-Garcia, E.3
-
86
-
-
33745034691
-
Mitochondrial disorders in renal tumors
-
Hervouet E, Godinot C. Mitochondrial disorders in renal tumors. Mitochondrion. 2006;6:105-117.
-
(2006)
Mitochondrion
, vol.6
, pp. 105-117
-
-
Hervouet, E.1
Godinot, C.2
-
87
-
-
33745623631
-
Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: Mechanism of tumorigenesis
-
Bi X, Lin Q, Foo TW, et al. Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis. Mol Cell Proteomics. 2006;5:1119-1130.
-
(2006)
Mol Cell Proteomics
, vol.5
, pp. 1119-1130
-
-
Bi, X.1
Lin, Q.2
Foo, T.W.3
-
89
-
-
33645026054
-
A transcriptome anatomy of human colorectal cancers
-
Lu B, Xu J, Lai M, Zhang H, Chen J. A transcriptome anatomy of human colorectal cancers. BMC Cancer. 2006;6:40.
-
(2006)
BMC Cancer
, vol.6
, pp. 40
-
-
Lu, B.1
Xu, J.2
Lai, M.3
Zhang, H.4
Chen, J.5
-
90
-
-
27944502154
-
Breast carcinomas fulfill the Warburg hypothesis and provide metabolic markers of cancer prognosis
-
Isidoro A, Casado E, Redondo A, et al. Breast carcinomas fulfill the Warburg hypothesis and provide metabolic markers of cancer prognosis. Carcinogenesis. 2005;26:2095-2104.
-
(2005)
Carcinogenesis
, vol.26
, pp. 2095-2104
-
-
Isidoro, A.1
Casado, E.2
Redondo, A.3
-
91
-
-
0037038669
-
Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells
-
Amuthan G, Biswas G, Ananadatheerthavarada HK, Vijayasarathy C, Shephard HM, Avadhani NG. Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells. Oncogene. 2002;21:7839-7849.
-
(2002)
Oncogene
, vol.21
, pp. 7839-7849
-
-
Amuthan, G.1
Biswas, G.2
Ananadatheerthavarada, H.K.3
Vijayasarathy, C.4
Shephard, H.M.5
Avadhani, N.G.6
-
92
-
-
34250624498
-
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck
-
Zhou S, Kachhap S, Sun W, et al. Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. Proc Natl Acad Sci USA. 2007;104:7540-7545.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7540-7545
-
-
Zhou, S.1
Kachhap, S.2
Sun, W.3
-
93
-
-
40749099894
-
Pyruvate kinase M2 is a phosphotyrosine-binding protein
-
Christofk HR, Vander Heiden MG, Wu N, et al. Pyruvate kinase M2 is a phosphotyrosine-binding protein. Nature. 2008;452:181-188.
-
(2008)
Nature
, vol.452
, pp. 181-188
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Wu, N.3
-
94
-
-
40749163248
-
The m2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
Christofk HR, Vander Heiden MG, Harris MH, et al. The m2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature. 2008;452:230-234.
-
(2008)
Nature
, vol.452
, pp. 230-234
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
-
95
-
-
33846002728
-
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
Bonnet S, Archer SL, Lalunis-Turner J, et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell. 2007;11:37-51.
-
(2007)
Cancer Cell
, vol.11
, pp. 37-51
-
-
Bonnet, S.1
Archer, S.L.2
Lalunis-Turner, J.3
-
96
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006;3:177-185.
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
97
-
-
0037189542
-
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
-
Lu H, Forbes RA, Verma A. Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis. J Biol Chem. 2002;277:23111-23115.
-
(2002)
J Biol Chem
, vol.277
, pp. 23111-23115
-
-
Lu, H.1
Forbes, R.A.2
Verma, A.3
-
98
-
-
33846317064
-
Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
-
Wu M, Neilson A, Swift AL, et al. Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells. Am J Physiol Cell Physiol. 2007;292:C125-C136.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Wu, M.1
Neilson, A.2
Swift, A.L.3
-
99
-
-
33947526130
-
AMP-activated protein kinase in the heart: Role during health and disease
-
Arad M, Seidman CE, Seidman JG. AMP-activated protein kinase in the heart: role during health and disease. Circ Res. 2007;100:474-488.
-
(2007)
Circ Res
, vol.100
, pp. 474-488
-
-
Arad, M.1
Seidman, C.E.2
Seidman, J.G.3
-
100
-
-
14544271907
-
AMP-activated protein kinase: Balancing the scales
-
Carling D. AMP-activated protein kinase: balancing the scales. Biochimie. 2005;87:87-91.
-
(2005)
Biochimie
, vol.87
, pp. 87-91
-
-
Carling, D.1
-
101
-
-
34247614521
-
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
-
Zhang H, Gao P, Fukuda R, et al. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell. 2007;11:407-420.
-
(2007)
Cancer Cell
, vol.11
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
-
102
-
-
0034710940
-
Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria
-
Deng Y, Wu X. Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria. Proc Natl Acad Sci USA. 2000;97:12050-12055.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12050-12055
-
-
Deng, Y.1
Wu, X.2
-
103
-
-
33746906633
-
Mitochondria in cancer
-
Kroemer G. Mitochondria in cancer. Oncogene. 2006;25:4630-4632.
-
(2006)
Oncogene
, vol.25
, pp. 4630-4632
-
-
Kroemer, G.1
-
104
-
-
0029890251
-
Molecular basis of hypoxia-induced erythropoietin expression
-
Wang GL, Semenza GL. Molecular basis of hypoxia-induced erythropoietin expression. Curr Opin Hematol. 1996;3:156-162.
-
(1996)
Curr Opin Hematol
, vol.3
, pp. 156-162
-
-
Wang, G.L.1
Semenza, G.L.2
-
105
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 1999;399:271-275.
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
-
107
-
-
10444223878
-
The hypoxia-inducible factor and tumor progression along the angiogenic pathway
-
Brahimi-Horn MC, Pouyssegur J. The hypoxia-inducible factor and tumor progression along the angiogenic pathway. Int Rev Cytol. 2005;242:157-213.
-
(2005)
Int Rev Cytol
, vol.242
, pp. 157-213
-
-
Brahimi-Horn, M.C.1
Pouyssegur, J.2
-
108
-
-
33845630758
-
Harnessing the hypoxia-inducible factor in cancer and ischemic disease
-
Brahimi-Horn MC, Pouyssegur J. Harnessing the hypoxia-inducible factor in cancer and ischemic disease. Biochem Pharmacol. 2007;73:450-457.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 450-457
-
-
Brahimi-Horn, M.C.1
Pouyssegur, J.2
-
109
-
-
33744457297
-
HIF-1: Hypoxia-inducible factor or dysoxia-inducible factor?
-
Lopez-Lazaro M. HIF-1: hypoxia-inducible factor or dysoxia-inducible factor? FASEB J. 2006;20:828-832.
-
(2006)
FASEB J
, vol.20
, pp. 828-832
-
-
Lopez-Lazaro, M.1
-
110
-
-
22144493866
-
Negative and positive regulation of HIF-1: A complex network
-
Bardos JI, Ashcroft M. Negative and positive regulation of HIF-1: a complex network. Biochim Biophys Acta. 2005;1755:107-120.
-
(2005)
Biochim Biophys Acta
, vol.1755
, pp. 107-120
-
-
Bardos, J.I.1
Ashcroft, M.2
-
111
-
-
33947498749
-
Hypoxia inducible factor-1 mediates effects of insulin on pancreatic cancer cells and disturbs host energy homeostasis
-
Wang F, Li SS, Segersvard R, et al. Hypoxia inducible factor-1 mediates effects of insulin on pancreatic cancer cells and disturbs host energy homeostasis. Am J Pathol. 2007;170:469-477.
-
(2007)
Am J Pathol
, vol.170
, pp. 469-477
-
-
Wang, F.1
Li, S.S.2
Segersvard, R.3
-
112
-
-
28644439593
-
Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer
-
Zhang D, Tai LK, Wong LL, Chiu LL, Sethi SK, Koay ES. Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer. Mol Cell Proteomics. 2005;4:1686-1696.
-
(2005)
Mol Cell Proteomics
, vol.4
, pp. 1686-1696
-
-
Zhang, D.1
Tai, L.K.2
Wong, L.L.3
Chiu, L.L.4
Sethi, S.K.5
Koay, E.S.6
-
113
-
-
1642453685
-
Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling
-
Kasuno K, Takabuchi S, Fukuda K, et al. Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling. J Biol Chem. 2004;279:2550-2558.
-
(2004)
J Biol Chem
, vol.279
, pp. 2550-2558
-
-
Kasuno, K.1
Takabuchi, S.2
Fukuda, K.3
-
114
-
-
0036710591
-
Signal transduction to hypoxia-inducible factor 1
-
Semenza G. Signal transduction to hypoxia-inducible factor 1. Biochem Pharmacol. 2002;64:993-998.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 993-998
-
-
Semenza, G.1
-
115
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza G. Targeting HIF-1 for cancer therapy. Nat Rev Cancer. 2003;3:1-13.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 1-13
-
-
Semenza, G.1
-
116
-
-
35348988020
-
Gene expression profile of B 16(F10) murine melanoma cells exposed to hypoxic conditions in vitro
-
Olbryt M, Jarzab M, Jazowiecka-Rakus J, Simek K, Szala S, Sochanik A. Gene expression profile of B 16(F10) murine melanoma cells exposed to hypoxic conditions in vitro. Gene Expr. 2006;13:191-203.
-
(2006)
Gene Expr
, vol.13
, pp. 191-203
-
-
Olbryt, M.1
Jarzab, M.2
Jazowiecka-Rakus, J.3
Simek, K.4
Szala, S.5
Sochanik, A.6
-
118
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
-
Talks KL, Turley H, Gatter KC, et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol. 2000;157:411-421.
-
(2000)
Am J Pathol
, vol.157
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
-
119
-
-
0037443587
-
Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma
-
Bos R, van der Groep P, Greijer AE, et al. Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma. Cancer. 2003;97:1573-1581.
-
(2003)
Cancer
, vol.97
, pp. 1573-1581
-
-
Bos, R.1
van der Groep, P.2
Greijer, A.E.3
-
120
-
-
0035027828
-
Transcription factor HIF-1 is a necessary mediator of the Pasteur effect in mammalian cells
-
Seagroves T, Ryan HE, Lu H, et al. Transcription factor HIF-1 is a necessary mediator of the Pasteur effect in mammalian cells. Mol Cell Biol. 2001;21:3436-3444.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3436-3444
-
-
Seagroves, T.1
Ryan, H.E.2
Lu, H.3
-
121
-
-
18644366801
-
Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors
-
Robey IF, Lien AD, Welsh SJ, Baggett BK, Gillies RJ. Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors. Neoplasia. 2005;7:324-330.
-
(2005)
Neoplasia
, vol.7
, pp. 324-330
-
-
Robey, I.F.1
Lien, A.D.2
Welsh, S.J.3
Baggett, B.K.4
Gillies, R.J.5
-
124
-
-
0034698178
-
Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
-
Osthus RC, Shim H, Kim S, et al. Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc. J Biol Chem. 2000;275:21797-21800.
-
(2000)
J Biol Chem
, vol.275
, pp. 21797-21800
-
-
Osthus, R.C.1
Shim, H.2
Kim, S.3
-
126
-
-
0030921103
-
c-Myc transactivation of LDH-A: Implications for tumor metabolism and growth
-
Shim H, Dolde C, Lewis BC, et al. c-Myc transactivation of LDH-A: implications for tumor metabolism and growth. Proc Natl Acad Sci USA. 1997;94:6658-6663.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6658-6663
-
-
Shim, H.1
Dolde, C.2
Lewis, B.C.3
-
127
-
-
0033039867
-
-
Papas KK, Sun L, Roos ES, Gounarides JS, Shapiro M, Nalin CM. Change in lactate production in Myc-transformed cells precedes apoptosis and can be inhibited by Bcl-2 overexpression. FEBS Lett. 1999;446:338-342.
-
Papas KK, Sun L, Roos ES, Gounarides JS, Shapiro M, Nalin CM. Change in lactate production in Myc-transformed cells precedes apoptosis and can be inhibited by Bcl-2 overexpression. FEBS Lett. 1999;446:338-342.
-
-
-
-
128
-
-
3142631736
-
HIF-1alpha induces cell cycle arrest by functionally counteracting Myc
-
Koshiji M, Kageyama Y, Pete EA, Horikawa I, Barrett JC, Huang LE. HIF-1alpha induces cell cycle arrest by functionally counteracting Myc. EMBO J. 2004;23:1949-1956.
-
(2004)
EMBO J
, vol.23
, pp. 1949-1956
-
-
Koshiji, M.1
Kageyama, Y.2
Pete, E.A.3
Horikawa, I.4
Barrett, J.C.5
Huang, L.E.6
-
129
-
-
34247614521
-
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
-
Zhang H, Gao P, Fukuda R, et al. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell. 2007;11:407-420.
-
(2007)
Cancer Cell
, vol.11
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
-
130
-
-
35649014840
-
Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
-
Kim JW, Gao P, Liu YC, Semenza GL, Dang CV. Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol Cell Biol. 2007;27:7381-7393.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7381-7393
-
-
Kim, J.W.1
Gao, P.2
Liu, Y.C.3
Semenza, G.L.4
Dang, C.V.5
-
132
-
-
0036632368
-
The phosphatidylinositol 3-kinase AKT pathway in human cancer
-
Vivanco I, Sawyers CL. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer. 2002;2:489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
133
-
-
0141927222
-
Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer
-
Gao N, Zhang Z, Jiang BH, Shi X. Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer. Biochem Biophys Res Commun. 2003;310:1124-1132.
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 1124-1132
-
-
Gao, N.1
Zhang, Z.2
Jiang, B.H.3
Shi, X.4
-
134
-
-
13844273087
-
PI3K-Akt pathway: Its functions and alterations in human cancer
-
Osaki M, Oshimura M, Ito H. PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis. 2004;9:667-676.
-
(2004)
Apoptosis
, vol.9
, pp. 667-676
-
-
Osaki, M.1
Oshimura, M.2
Ito, H.3
-
135
-
-
13844273087
-
PI3K-Akt pathway: Its functions and alterations in human cancer
-
Osaki M, Oshimura M, Ito H. PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis. 2004;9:667-676.
-
(2004)
Apoptosis
, vol.9
, pp. 667-676
-
-
Osaki, M.1
Oshimura, M.2
Ito, H.3
-
136
-
-
4444223702
-
Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling
-
Ihle NT, Williams R, Chow S, et al. Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling. Mol Cancer Ther. 2004;3:763-772.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 763-772
-
-
Ihle, N.T.1
Williams, R.2
Chow, S.3
-
137
-
-
0032189381
-
Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
-
Coffer PJ, Jin J, Woodgett JR. Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J. 1998;335:1-13.
-
(1998)
Biochem J
, vol.335
, pp. 1-13
-
-
Coffer, P.J.1
Jin, J.2
Woodgett, J.R.3
-
138
-
-
30944442856
-
The Akt pathway in human breast cancer: A tissue-array-based analysis
-
Bose S, Chandran S, Mirocha JM, Bose N. The Akt pathway in human breast cancer: a tissue-array-based analysis. Mod Pathol. 2006;19:238-245.
-
(2006)
Mod Pathol
, vol.19
, pp. 238-245
-
-
Bose, S.1
Chandran, S.2
Mirocha, J.M.3
Bose, N.4
-
139
-
-
28644435769
-
Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer
-
Lin HJ, Hsieh FC, Song H, Lin J. Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer. Br J Cancer. 2005;93:1372-1381.
-
(2005)
Br J Cancer
, vol.93
, pp. 1372-1381
-
-
Lin, H.J.1
Hsieh, F.C.2
Song, H.3
Lin, J.4
-
140
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
Elstrom RL, Bauer DE, Buzzai M, et al. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res. 2004;64:3892-3899.
-
(2004)
Cancer Res
, vol.64
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
-
141
-
-
26644449670
-
The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells
-
She QB, Solit DB, Ye Q, O'Reilly KE, Lobo J, Rosen N. The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells. Cancer Cell. 2005;8:287-297.
-
(2005)
Cancer Cell
, vol.8
, pp. 287-297
-
-
She, Q.B.1
Solit, D.B.2
Ye, Q.3
O'Reilly, K.E.4
Lobo, J.5
Rosen, N.6
-
143
-
-
20544449673
-
The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation
-
Buzzai M, Bauer DE, Jones RG, et al. The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation. Oncogene. 2005;24:4165-4173.
-
(2005)
Oncogene
, vol.24
, pp. 4165-4173
-
-
Buzzai, M.1
Bauer, D.E.2
Jones, R.G.3
-
145
-
-
0027234492
-
A comparison of the biological activities of wild-type and mutant p53
-
Zambetti GP, Levine AJ. A comparison of the biological activities of wild-type and mutant p53. FASEB J. 1993;7:855-865.
-
(1993)
FASEB J
, vol.7
, pp. 855-865
-
-
Zambetti, G.P.1
Levine, A.J.2
-
146
-
-
0026718812
-
The p53 tumor suppressor protein, a modulator of cell proliferation
-
Ullrich SJ, Anderson CW, Mercer WE, Appella E. The p53 tumor suppressor protein, a modulator of cell proliferation. J Biol Chem. 1992;267:15259-15262.
-
(1992)
J Biol Chem
, vol.267
, pp. 15259-15262
-
-
Ullrich, S.J.1
Anderson, C.W.2
Mercer, W.E.3
Appella, E.4
-
147
-
-
0033013985
-
Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts
-
Vaziri H, Squire JA, Pandita TK, et al. Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts. Mol Cell Biol. 1999;19:2373-2379.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2373-2379
-
-
Vaziri, H.1
Squire, J.A.2
Pandita, T.K.3
-
148
-
-
34249681337
-
-
Bensaad K, Vousden KH. p53: new roles in metabolism. Trends Cell Biol. 2007;17:286-291.
-
Bensaad K, Vousden KH. p53: new roles in metabolism. Trends Cell Biol. 2007;17:286-291.
-
-
-
-
149
-
-
11144333835
-
Global investigation of p53-induced apoptosis through quantitative proteomic profiling using comparative amino acid-coded tagging
-
Gu S, Liu Z, Pan S, et al. Global investigation of p53-induced apoptosis through quantitative proteomic profiling using comparative amino acid-coded tagging. Mol Cell Proteomics. 2004;3:998-1008.
-
(2004)
Mol Cell Proteomics
, vol.3
, pp. 998-1008
-
-
Gu, S.1
Liu, Z.2
Pan, S.3
-
150
-
-
1942506067
-
The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
-
Schwartzenberg-Bar-Yoseph F, Armoni M, Karnieli E. The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res. 2004;64:2627-2633.
-
(2004)
Cancer Res
, vol.64
, pp. 2627-2633
-
-
Schwartzenberg-Bar-Yoseph, F.1
Armoni, M.2
Karnieli, E.3
-
151
-
-
33745149291
-
p53 regulates mitochondrial respiration
-
Matoba S, Kang JG, Patino WD, et al. p53 regulates mitochondrial respiration. Science. 2006;312:1650-1653.
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
-
152
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
Bensaad K, Tsuruta A, Selak MA, et al. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell. 2006;126:107-120.
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
-
153
-
-
0030898182
-
Identification of PRG1, a novel progestin-responsive gene with sequence homology to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
-
Hamilton JA, Callaghan MJ, Sutherland RL, Watts CK. Identification of PRG1, a novel progestin-responsive gene with sequence homology to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Mol Endocrinol. 1997;11:490-502.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 490-502
-
-
Hamilton, J.A.1
Callaghan, M.J.2
Sutherland, R.L.3
Watts, C.K.4
-
154
-
-
33747505788
-
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and tumor cell glycolysis
-
Chesney J. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and tumor cell glycolysis. Curr Opin Clin Nutr Metab Care. 2006;9:535-539.
-
(2006)
Curr Opin Clin Nutr Metab Care
, vol.9
, pp. 535-539
-
-
Chesney, J.1
-
155
-
-
9144236903
-
Identification and characterization of the hypoxia-responsive element of the human placental 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene
-
Fukasawa M, Tsuchiya T, Takayama E, et al. Identification and characterization of the hypoxia-responsive element of the human placental 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene. J Biochem (Tokyo). 2004;136:273-277.
-
(2004)
J Biochem (Tokyo)
, vol.136
, pp. 273-277
-
-
Fukasawa, M.1
Tsuchiya, T.2
Takayama, E.3
-
156
-
-
0037108709
-
High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers
-
Atsumi T, Chesney J, Metz C, et al. High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers. Cancer Res. 2002;62:5881-5887.
-
(2002)
Cancer Res
, vol.62
, pp. 5881-5887
-
-
Atsumi, T.1
Chesney, J.2
Metz, C.3
-
157
-
-
23844517036
-
Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer
-
Bando H, Atsumi T, Nishio T, et al. Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer. Clin Cancer Res. 2005;11:5784-5792.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5784-5792
-
-
Bando, H.1
Atsumi, T.2
Nishio, T.3
-
158
-
-
0033057367
-
An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: Role in tumor cell glycolysis and the Warburg effect
-
Chesney J, Mitchell R, Benigni F, et al. An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect. Proc Natl Acad Sci USA. 1999;96:3047-3052.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3047-3052
-
-
Chesney, J.1
Mitchell, R.2
Benigni, F.3
-
160
-
-
0024376173
-
-
Bos JL. ras oncogenes in human cancer: a review. Cancer Res. 1989;49:4682-4689.
-
Bos JL. ras oncogenes in human cancer: a review. Cancer Res. 1989;49:4682-4689.
-
-
-
-
161
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer. 2003;3:11-22.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
162
-
-
0034684620
-
Signal transduction and the Ets family of transcription factors
-
Yordy JS, Muise-Helmericks RC. Signal transduction and the Ets family of transcription factors. Oncogene. 2000;19:6503-6513.
-
(2000)
Oncogene
, vol.19
, pp. 6503-6513
-
-
Yordy, J.S.1
Muise-Helmericks, R.C.2
-
163
-
-
0033635157
-
Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma
-
Pacold ME, Suire S, Perisic O, et al. Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma. Cell. 2000;103:931-943.
-
(2000)
Cell
, vol.103
, pp. 931-943
-
-
Pacold, M.E.1
Suire, S.2
Perisic, O.3
-
164
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana P, Warne PH, Dhand R, et al. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature. 1994;370:527-532.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
-
166
-
-
33745472798
-
E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition
-
Blum R, Nakdimon I, Goldberg L, et al. E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition. Int J Cancer. 2006;119:527-538.
-
(2006)
Int J Cancer
, vol.119
, pp. 527-538
-
-
Blum, R.1
Nakdimon, I.2
Goldberg, L.3
-
167
-
-
0035909527
-
Metabolic cooperation between different oncogenes during cell transformation: Interaction between activated ras and HPV-16 E7
-
Mazurek S, Zwerschke W, Jansen-Durr P, Eigenbrodt E. Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7. Oncogene. 2001;20:6891-6898.
-
(2001)
Oncogene
, vol.20
, pp. 6891-6898
-
-
Mazurek, S.1
Zwerschke, W.2
Jansen-Durr, P.3
Eigenbrodt, E.4
-
168
-
-
17844383964
-
Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements
-
Ramanathan A, Wang C, Schreiber SL. Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci USA. 2005;102:5992-5997.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5992-5997
-
-
Ramanathan, A.1
Wang, C.2
Schreiber, S.L.3
-
169
-
-
21344473888
-
K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts
-
Vizan P, Boros LG, Figueras A, et al. K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts. Cancer Res. 2005;65:5512-5515.
-
(2005)
Cancer Res
, vol.65
, pp. 5512-5515
-
-
Vizan, P.1
Boros, L.G.2
Figueras, A.3
-
171
-
-
0031465906
-
Proliferation of human malignant astrocytomas is dependent on Ras activation
-
Guha A, Feldkamp MM, Lau N, Boss G, Pawson A. Proliferation of human malignant astrocytomas is dependent on Ras activation. Oncogene. 1997;15:2755-2765.
-
(1997)
Oncogene
, vol.15
, pp. 2755-2765
-
-
Guha, A.1
Feldkamp, M.M.2
Lau, N.3
Boss, G.4
Pawson, A.5
-
172
-
-
13444283313
-
Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death
-
Blum R, Jacob-Hirsch J, Amariglio N, Rechavi G, Kloog Y. Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. Cancer Res. 2005;65:999-1006.
-
(2005)
Cancer Res
, vol.65
, pp. 999-1006
-
-
Blum, R.1
Jacob-Hirsch, J.2
Amariglio, N.3
Rechavi, G.4
Kloog, Y.5
-
173
-
-
0025854920
-
Regulation of 6-phosphofructo-1-kinase activity in ras-transformed rat-1 fibroblasts
-
Kole HK, Resnick RJ, Van Doren M, Racker E. Regulation of 6-phosphofructo-1-kinase activity in ras-transformed rat-1 fibroblasts. Arch Biochem Biophys. 1991;286:586-590.
-
(1991)
Arch Biochem Biophys
, vol.286
, pp. 586-590
-
-
Kole, H.K.1
Resnick, R.J.2
Van Doren, M.3
Racker, E.4
-
174
-
-
0022364146
-
Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes
-
Racker E, Resnick RJ, Feldman R. Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes. Proc Natl Acad Sci USA. 1985;82:3535-3538.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 3535-3538
-
-
Racker, E.1
Resnick, R.J.2
Feldman, R.3
-
175
-
-
33747487110
-
Ras transformation requires metabolic control by 6-phosphofructo-2-kinase
-
Telang S, Yalcin A, Clem AL, et al. Ras transformation requires metabolic control by 6-phosphofructo-2-kinase. Oncogene. 2006;25:7225-7234.
-
(2006)
Oncogene
, vol.25
, pp. 7225-7234
-
-
Telang, S.1
Yalcin, A.2
Clem, A.L.3
-
176
-
-
0026467983
-
Double role for pyruvate kinase type M2 in the expansion of phosphometabolite pools found in tumor cells
-
Eigenbrodt E, Reinacher M, Scheefers-Borchel U, Scheefers H, Friis R. Double role for pyruvate kinase type M2 in the expansion of phosphometabolite pools found in tumor cells. Crit Rev Oncog. 1992;3:91-115.
-
(1992)
Crit Rev Oncog
, vol.3
, pp. 91-115
-
-
Eigenbrodt, E.1
Reinacher, M.2
Scheefers-Borchel, U.3
Scheefers, H.4
Friis, R.5
-
177
-
-
0030683603
-
The role of phosphometabolites in cell proliferation, energy metabolism, and tumor therapy
-
Mazurek S, Boschek CB, Eigenbrodt E. The role of phosphometabolites in cell proliferation, energy metabolism, and tumor therapy. J Bioenerg Biomembr. 1997;29:315-330.
-
(1997)
J Bioenerg Biomembr
, vol.29
, pp. 315-330
-
-
Mazurek, S.1
Boschek, C.B.2
Eigenbrodt, E.3
-
178
-
-
0031040469
-
Effect of extracellular AMP on cell proliferation and metabolism of breast cancer cell lines with high and low glycolytic rates
-
Mazurek S, Michel A, Eigenbrodt E. Effect of extracellular AMP on cell proliferation and metabolism of breast cancer cell lines with high and low glycolytic rates. J Biol Chem. 1997;272:4941-4952.
-
(1997)
J Biol Chem
, vol.272
, pp. 4941-4952
-
-
Mazurek, S.1
Michel, A.2
Eigenbrodt, E.3
-
179
-
-
33846591472
-
Genetic intra-tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours
-
Khalique L, Ayhan A, Weale ME, Jacobs IJ, Ramus SJ, Gayther SA. Genetic intra-tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours. J Pathol. 2007;211:286-295.
-
(2007)
J Pathol
, vol.211
, pp. 286-295
-
-
Khalique, L.1
Ayhan, A.2
Weale, M.E.3
Jacobs, I.J.4
Ramus, S.J.5
Gayther, S.A.6
-
180
-
-
39049176440
-
Chromosome 22 array-CGH profiling of breast cancer delimited minimal common regions of genomic imbalances and revealed frequent intra-tumoral genetic heterogeneity
-
Benetkiewicz M, Piotrowski A, Diaz De Ståhl T, et al. Chromosome 22 array-CGH profiling of breast cancer delimited minimal common regions of genomic imbalances and revealed frequent intra-tumoral genetic heterogeneity. Int J Oncol. 2006;29:935-945.
-
(2006)
Int J Oncol
, vol.29
, pp. 935-945
-
-
Benetkiewicz, M.1
Piotrowski, A.2
Diaz, D.3
Ståhl, T.4
-
181
-
-
16444374716
-
Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer
-
Pan H, Califano J, Ponte JF, et al. Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer. Cancer Res. 2005;65:1664-1669.
-
(2005)
Cancer Res
, vol.65
, pp. 1664-1669
-
-
Pan, H.1
Califano, J.2
Ponte, J.F.3
-
182
-
-
19844364343
-
Evolution of intratumoral genetic heterogeneity during colorectal cancer progression
-
Losi L, Baisse B, Bouzourene H, Benhattar J. Evolution of intratumoral genetic heterogeneity during colorectal cancer progression. Carcinogenesis. 2005;26:916-922.
-
(2005)
Carcinogenesis
, vol.26
, pp. 916-922
-
-
Losi, L.1
Baisse, B.2
Bouzourene, H.3
Benhattar, J.4
-
183
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer. 2004;4:891-899.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
184
-
-
35448940364
-
Adaptive landscapes and emergent phenotypes: Why do cancers have high glycolysis?
-
Gillies RJ, Gatenby RA. Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis? J Bioenerg Biomembr. 2007;39:251-257.
-
(2007)
J Bioenerg Biomembr
, vol.39
, pp. 251-257
-
-
Gillies, R.J.1
Gatenby, R.A.2
-
185
-
-
34447094919
-
Glycolysis in cancer: A potential target for therapy
-
Gatenby RA, Gillies RJ. Glycolysis in cancer: a potential target for therapy. Int J Biochem Cell Biol. 2007;39:1358-1366.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 1358-1366
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
186
-
-
34547124566
-
Hypoxia and adaptive landscapes in the evolution of carcinogenesis
-
Gillies RJ, Gatenby RA. Hypoxia and adaptive landscapes in the evolution of carcinogenesis. Cancer Metastasis Rev. 2007;26:311-317.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 311-317
-
-
Gillies, R.J.1
Gatenby, R.A.2
-
187
-
-
0347694776
-
Cancer metabolism: Facts, fantasy, and fiction
-
Zu X, Guppy M. Cancer metabolism: facts, fantasy, and fiction. Biochem Biophys Res Commun. 2008;313:459-465.
-
(2008)
Biochem Biophys Res Commun
, vol.313
, pp. 459-465
-
-
Zu, X.1
Guppy, M.2
-
188
-
-
0037093411
-
Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells
-
Guppy M, Leedman P, Zu X, Russell V. Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells. Biochem J. 2002;364:309-315.
-
(2002)
Biochem J
, vol.364
, pp. 309-315
-
-
Guppy, M.1
Leedman, P.2
Zu, X.3
Russell, V.4
-
190
-
-
0035226522
-
Why are cancers acidic? A carrier-mediated diffusion model for H+ transport in the interstitial fluid
-
Griffiths JR, McIntyre DJ, Howe FA, Stubbs M. Why are cancers acidic? A carrier-mediated diffusion model for H+ transport in the interstitial fluid. Novartis Found Symp. 2001;240:46-62.
-
(2001)
Novartis Found Symp
, vol.240
, pp. 46-62
-
-
Griffiths, J.R.1
McIntyre, D.J.2
Howe, F.A.3
Stubbs, M.4
-
191
-
-
0036554644
-
Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism
-
Helmlinger G, Sckell A, Dellian M, Forbes NS, Jain RK. Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism. Clin Cancer Res. 2002;8:1284-1291.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1284-1291
-
-
Helmlinger, G.1
Sckell, A.2
Dellian, M.3
Forbes, N.S.4
Jain, R.K.5
-
192
-
-
33749495312
-
Estradiol stimulates the biosynthetic pathways of breast cancer cells: Detection by metabolic flux analysis
-
Forbes NS, Meadows AL, Clark DS, Blanch HW. Estradiol stimulates the biosynthetic pathways of breast cancer cells: detection by metabolic flux analysis. Metab Eng. 2006;8:639-652.
-
(2006)
Metab Eng
, vol.8
, pp. 639-652
-
-
Forbes, N.S.1
Meadows, A.L.2
Clark, D.S.3
Blanch, H.W.4
-
193
-
-
24144498480
-
Rapid simulation and analysis of isotopomer distributions using constraints based on enzyme mechanisms: An example from HT29 cancer cells
-
Selivanov VA, Meshalkina LE, Solovjeva ON, et al. Rapid simulation and analysis of isotopomer distributions using constraints based on enzyme mechanisms: an example from HT29 cancer cells. Bioinformatics. 2005;21:3558-3564.
-
(2005)
Bioinformatics
, vol.21
, pp. 3558-3564
-
-
Selivanov, V.A.1
Meshalkina, L.E.2
Solovjeva, O.N.3
-
194
-
-
33751569560
-
Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer
-
Ramos-Montoya A, Lee WN, Bassilian S, et al. Pentose phosphate cycle oxidative and nonoxidative balance: a new vulnerable target for overcoming drug resistance in cancer. Int J Cancer. 2006;119:2733-2741.
-
(2006)
Int J Cancer
, vol.119
, pp. 2733-2741
-
-
Ramos-Montoya, A.1
Lee, W.N.2
Bassilian, S.3
-
195
-
-
0027619301
-
Dehydrogenases of pentose phosphate pathway and cervical carcinogenesis
-
Kumar A, Pundir CS, Sharma S, Sharma A. Dehydrogenases of pentose phosphate pathway and cervical carcinogenesis. Indian J Exp Biol. 1993;31:569-570.
-
(1993)
Indian J Exp Biol
, vol.31
, pp. 569-570
-
-
Kumar, A.1
Pundir, C.S.2
Sharma, S.3
Sharma, A.4
-
196
-
-
33847755430
-
Adaptation of energy metabolism in breast cancer brain metastases
-
Chen EI, Hewel J, Krueger JS, et al. Adaptation of energy metabolism in breast cancer brain metastases. Cancer Res. 2007;67:1472-1486.
-
(2007)
Cancer Res
, vol.67
, pp. 1472-1486
-
-
Chen, E.I.1
Hewel, J.2
Krueger, J.S.3
-
197
-
-
0031974007
-
Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: Is cancer a disease of cellular glucose metabolism?
-
Boros LG, Lee PW, Brandes JL, et al. Nonoxidative pentose phosphate pathways and their direct role in ribose synthesis in tumors: is cancer a disease of cellular glucose metabolism? Med Hypotheses. 1998;50:55-59.
-
(1998)
Med Hypotheses
, vol.50
, pp. 55-59
-
-
Boros, L.G.1
Lee, P.W.2
Brandes, J.L.3
-
198
-
-
0035984647
-
Going malignant: The hypoxia-cancer connection in the prostate
-
Hochachka PW, Rupert JL, Goldenberg L, Gleave M, Kozlowski P. Going malignant: the hypoxia-cancer connection in the prostate. Bioessays. 2002;24:749-757.
-
(2002)
Bioessays
, vol.24
, pp. 749-757
-
-
Hochachka, P.W.1
Rupert, J.L.2
Goldenberg, L.3
Gleave, M.4
Kozlowski, P.5
-
199
-
-
33751569560
-
Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer
-
Ramos-Montoya A, Lee WN, Bassilian S, et al. Pentose phosphate cycle oxidative and nonoxidative balance: a new vulnerable target for overcoming drug resistance in cancer. Int J Cancer. 2006;119:2733-2741.
-
(2006)
Int J Cancer
, vol.119
, pp. 2733-2741
-
-
Ramos-Montoya, A.1
Lee, W.N.2
Bassilian, S.3
-
200
-
-
0028301959
-
Fatty acid synthesis: A potential selective target for antineoplastic therapy
-
Kuhajda FP, Jenner K, Wood FD, et al. Fatty acid synthesis: a potential selective target for antineoplastic therapy. Proc Natl Acad Sci USA. 1994;91:6379-6383.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6379-6383
-
-
Kuhajda, F.P.1
Jenner, K.2
Wood, F.D.3
-
201
-
-
34447300423
-
Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer
-
Knowles LM, Smith JW. Genome-wide changes accompanying knockdown of fatty acid synthase in breast cancer. BMC Genomics. 2007;8:168.
-
(2007)
BMC Genomics
, vol.8
, pp. 168
-
-
Knowles, L.M.1
Smith, J.W.2
-
202
-
-
0035984647
-
Going malignant: The hypoxia-cancer connection in the prostate
-
Hochachka PW, Rupert JL, Goldenberg L, Gleave M, Kozlowski P. Going malignant: the hypoxia-cancer connection in the prostate. Bioessays. 2002;24:749-757.
-
(2002)
Bioessays
, vol.24
, pp. 749-757
-
-
Hochachka, P.W.1
Rupert, J.L.2
Goldenberg, L.3
Gleave, M.4
Kozlowski, P.5
-
203
-
-
0027619301
-
Dehydrogenases of pentose phosphate pathway and cervical carcinogenesis
-
Kumar A, Pundir CS, Sharma S, Sharma A. Dehydrogenases of pentose phosphate pathway and cervical carcinogenesis. Indian J Exp Biol. 1993;31:569-570.
-
(1993)
Indian J Exp Biol
, vol.31
, pp. 569-570
-
-
Kumar, A.1
Pundir, C.S.2
Sharma, S.3
Sharma, A.4
-
204
-
-
33344456073
-
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted
-
Langbein S, Zerilli M, Zur HA, et al. Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted. Br J Cancer. 2006;94:578-585.
-
(2006)
Br J Cancer
, vol.94
, pp. 578-585
-
-
Langbein, S.1
Zerilli, M.2
HA, Z.3
-
206
-
-
8844249356
-
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH
-
Svastova E, Hulikova A, Rafajova M, et al. Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH. FEBS Lett. 2004;577:439-445.
-
(2004)
FEBS Lett
, vol.577
, pp. 439-445
-
-
Svastova, E.1
Hulikova, A.2
Rafajova, M.3
-
207
-
-
33847649279
-
HIF-1alpha and CA IX staining in invasive breast carcinomas: Prognosis and treatment outcome
-
Trastour C, Benizri E, Ettore F, et al. HIF-1alpha and CA IX staining in invasive breast carcinomas: prognosis and treatment outcome. Int J Cancer. 2007;120:1451-1458.
-
(2007)
Int J Cancer
, vol.120
, pp. 1451-1458
-
-
Trastour, C.1
Benizri, E.2
Ettore, F.3
-
208
-
-
0035420015
-
1H magnetic resonance spectroscopic imaging: Comparison with maps of metabolites
-
1H magnetic resonance spectroscopic imaging: comparison with maps of metabolites. Cancer Res. 2001;61:6524-6531.
-
(2001)
Cancer Res
, vol.61
, pp. 6524-6531
-
-
Garcia-Martin, M.L.1
Herigault, G.2
Remy, C.3
-
209
-
-
33646917296
-
The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism
-
Ullah MS, Davies AJ, Halestrap AP. The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism. J Biol Chem. 2006;281:9030-9037.
-
(2006)
J Biol Chem
, vol.281
, pp. 9030-9037
-
-
Ullah, M.S.1
Davies, A.J.2
Halestrap, A.P.3
-
210
-
-
0035237389
-
pHi, aerobic glycolysis and vascular endothelial growth factor in tumour growth
-
Pouyssegur J, Franchi A, Pages G. pHi, aerobic glycolysis and vascular endothelial growth factor in tumour growth. Novartis Found Symp. 2001;240:186-196.
-
(2001)
Novartis Found Symp
, vol.240
, pp. 186-196
-
-
Pouyssegur, J.1
Franchi, A.2
Pages, G.3
-
211
-
-
0345389967
-
pH and drug resistance. II. Turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs
-
Raghunand N, Martinez-Zaguilan R, Wright SH, Gillies RJ. pH and drug resistance. II. Turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs. Biochem Pharmacol. 1999;57:1047-1058.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 1047-1058
-
-
Raghunand, N.1
Martinez-Zaguilan, R.2
Wright, S.H.3
Gillies, R.J.4
-
212
-
-
0027373117
-
Vacuolar type proton ATPases are functionally expressed in the plasma membranes of human tumor cells
-
Martinez-Zaguilan R, Lynch RM, Martinez GM, Gillies RJ. Vacuolar type proton ATPases are functionally expressed in the plasma membranes of human tumor cells. Am J Physiol. 1993;265:c1015-c1029.
-
(1993)
Am J Physiol
, vol.265
-
-
Martinez-Zaguilan, R.1
Lynch, R.M.2
Martinez, G.M.3
Gillies, R.J.4
-
213
-
-
0021732164
-
The relevance of tumour pH to the treatment of malignant disease
-
Wike-Hooley JL, Haveman J, Reinhold HS. The relevance of tumour pH to the treatment of malignant disease. Radiother Oncol. 1984;2:343-366.
-
(1984)
Radiother Oncol
, vol.2
, pp. 343-366
-
-
Wike-Hooley, J.L.1
Haveman, J.2
Reinhold, H.S.3
-
214
-
-
0024379967
-
Acid pH in tumors and its potential for therapeutic exploitation
-
Tannock IF, Rotin D. Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res. 1989;49:4373-4384.
-
(1989)
Cancer Res
, vol.49
, pp. 4373-4384
-
-
Tannock, I.F.1
Rotin, D.2
-
216
-
-
0030614893
-
2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
-
2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nature. 1997;3:177-182.
-
(1997)
Nature
, vol.3
, pp. 177-182
-
-
Helmlinger, G.1
Yuan, F.2
Jain, M.D.3
Jain, R.4
-
217
-
-
0027388949
-
Studies with glycolysis-deficient cells suggest that production of lactic acid is not the only cause of tumor acidity
-
Newell K, Franchi A, Pouyssegur J, Tannock I. Studies with glycolysis-deficient cells suggest that production of lactic acid is not the only cause of tumor acidity. Proc Natl Acad Sci USA. 1993;90:1127-1131.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1127-1131
-
-
Newell, K.1
Franchi, A.2
Pouyssegur, J.3
Tannock, I.4
-
218
-
-
0036554644
-
Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism
-
Helmlinger G, Sckell A, Dellian M, Forbes NS, Jain RK. Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism. Clin Cancer Res. 2002;8:1284-1291.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1284-1291
-
-
Helmlinger, G.1
Sckell, A.2
Dellian, M.3
Forbes, N.S.4
Jain, R.K.5
-
219
-
-
0020149736
-
Down-regulation of the hexose transport system: Metabolic basis studied with a fibroblast mutant lacking phosphoglucose isomerase
-
Ullrey DB, Franchi A, Pouyssegur J, Kalckar HM. Down-regulation of the hexose transport system: metabolic basis studied with a fibroblast mutant lacking phosphoglucose isomerase. Proc Natl Acad Sci USA. 1982;79:3777-3779.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 3777-3779
-
-
Ullrey, D.B.1
Franchi, A.2
Pouyssegur, J.3
Kalckar, H.M.4
-
220
-
-
33746149756
-
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
-
Rofstad EK, Mathiesen B, Kindem K, Galappathi K. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res. 2006;66:6699-6707.
-
(2006)
Cancer Res
, vol.66
, pp. 6699-6707
-
-
Rofstad, E.K.1
Mathiesen, B.2
Kindem, K.3
Galappathi, K.4
-
221
-
-
0034651918
-
Cathepsin D in breast cancer: Mechanisms and clinical applications, a 1999 overview
-
Rochefort H, Garcia M, Glondu M, et al. Cathepsin D in breast cancer: mechanisms and clinical applications, a 1999 overview. Clin Chim Acta. 2000;291:157-170.
-
(2000)
Clin Chim Acta
, vol.291
, pp. 157-170
-
-
Rochefort, H.1
Garcia, M.2
Glondu, M.3
-
224
-
-
70449246776
-
Calculation of intracellular pH from the distribution of 5,5-dimethyl-2,4-oxazolidinedione (DMO): Application to skeletal muscle of the dog
-
Waddell WJ, Butler TC. Calculation of intracellular pH from the distribution of 5,5-dimethyl-2,4-oxazolidinedione (DMO): application to skeletal muscle of the dog. J Clin Invest. 1959;38:720-729.
-
(1959)
J Clin Invest
, vol.38
, pp. 720-729
-
-
Waddell, W.J.1
Butler, T.C.2
-
226
-
-
0025771650
-
Are cancer cells acidic?
-
Griffiths JR. Are cancer cells acidic? Br J Cancer. 1991;64:425-427.
-
(1991)
Br J Cancer
, vol.64
, pp. 425-427
-
-
Griffiths, J.R.1
-
227
-
-
0028465482
-
31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate
-
31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. Am J Physiol. 1994;267:C195-C203.
-
(1994)
Am J Physiol
, vol.267
-
-
Gillies, R.J.1
Liu, Z.2
Bhujwalla, Z.3
-
230
-
-
0036194956
-
Combined vascular and extracellular pH imaging of solid tumors
-
Bhujwalla ZM, Artemov D, Ballesteros P, Cerdan S, Gillies RJ, Solaiyappan M. Combined vascular and extracellular pH imaging of solid tumors. NMR Biomed. 2002;15:114-119.
-
(2002)
NMR Biomed
, vol.15
, pp. 114-119
-
-
Bhujwalla, Z.M.1
Artemov, D.2
Ballesteros, P.3
Cerdan, S.4
Gillies, R.J.5
Solaiyappan, M.6
-
232
-
-
0033038869
-
Transmembrane pH gradients in vivo: Measurements using fluorinated vitamin B6 derivatives
-
Mason RP. Transmembrane pH gradients in vivo: measurements using fluorinated vitamin B6 derivatives. Curr Med Chem. 1999;6:481-499.
-
(1999)
Curr Med Chem
, vol.6
, pp. 481-499
-
-
Mason, R.P.1
-
234
-
-
32544443295
-
High resolution pH(e) imaging of rat glioma using pH-dependent relaxivity
-
Garcia-Martin ML, Martinez GV, Raghunand N, Sherry AD, Zhang S, Gillies RJ. High resolution pH(e) imaging of rat glioma using pH-dependent relaxivity. Magn Reson Med. 2006;55:309-315.
-
(2006)
Magn Reson Med
, vol.55
, pp. 309-315
-
-
Garcia-Martin, M.L.1
Martinez, G.V.2
Raghunand, N.3
Sherry, A.D.4
Zhang, S.5
Gillies, R.J.6
-
235
-
-
0033517750
-
A novel pH-sensitive MRI contrast agent
-
Zhang S, Wu K, Sherry AD. A novel pH-sensitive MRI contrast agent. Angewandte Chemie. 1999;38:3192-3194.
-
(1999)
Angewandte Chemie
, vol.38
, pp. 3192-3194
-
-
Zhang, S.1
Wu, K.2
Sherry, A.D.3
-
237
-
-
33748342737
-
R2/R1 ratiometric procedure for a concentration-independent, pH-responsive, Gd(III)-based MRI agent
-
Aime S, Fedeli F, Sanino A, Terreno EA. R2/R1 ratiometric procedure for a concentration-independent, pH-responsive, Gd(III)-based MRI agent. J Am Chem Soc. 2006;128:11326-11327.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 11326-11327
-
-
Aime, S.1
Fedeli, F.2
Sanino, A.3
Terreno, E.A.4
-
238
-
-
32544443295
-
High resolution pH(e) imaging of rat glioma using pH-dependent relaxivity
-
Garcia-Martin ML, Martinez GV, Raghunand N, Sherry AD, Zhang S, Gillies RJ. High resolution pH(e) imaging of rat glioma using pH-dependent relaxivity. Magn Reson Med. 2006;55:309-315.
-
(2006)
Magn Reson Med
, vol.55
, pp. 309-315
-
-
Garcia-Martin, M.L.1
Martinez, G.V.2
Raghunand, N.3
Sherry, A.D.4
Zhang, S.5
Gillies, R.J.6
-
239
-
-
0037310125
-
Renal and systemic pH imaging by contrast-enhanced MRI
-
Raghunand N, Howison C, Sherry AD, Zhang S, Gillies RJ. Renal and systemic pH imaging by contrast-enhanced MRI. Magn Reson Med. 2003;49:249-257.
-
(2003)
Magn Reson Med
, vol.49
, pp. 249-257
-
-
Raghunand, N.1
Howison, C.2
Sherry, A.D.3
Zhang, S.4
Gillies, R.J.5
-
240
-
-
0033766573
-
Determination of pH using water protons and chemical exchange dependent saturation transfer (CEST)
-
Ward KM, Balaban RS. Determination of pH using water protons and chemical exchange dependent saturation transfer (CEST). Magn Reson Med. 2000;44:799-802.
-
(2000)
Magn Reson Med
, vol.44
, pp. 799-802
-
-
Ward, K.M.1
Balaban, R.S.2
-
241
-
-
0034145982
-
A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST)
-
Ward KM, Aletras AH, Balaban RS. A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST). J Magn Reson. 2000;143:79-87.
-
(2000)
J Magn Reson
, vol.143
, pp. 79-87
-
-
Ward, K.M.1
Aletras, A.H.2
Balaban, R.S.3
-
242
-
-
0042466426
-
Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI
-
Zhou J, Payen JF, Wilson DA, Traystman RJ, van Zijl PC. Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI. Nat Med. 2003;9:1085-1090.
-
(2003)
Nat Med
, vol.9
, pp. 1085-1090
-
-
Zhou, J.1
Payen, J.F.2
Wilson, D.A.3
Traystman, R.J.4
van Zijl, P.C.5
-
243
-
-
0036204319
-
Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications
-
Aime S, Barge A, Delli CD, et al. Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications. Magn Reson Med. 2002;47:639-648.
-
(2002)
Magn Reson Med
, vol.47
, pp. 639-648
-
-
Aime, S.1
Barge, A.2
Delli, C.D.3
-
244
-
-
33744523144
-
Paramagnetic lanthanide complexes as PARACEST agents for medical imaging
-
Woods M, Woessner DE, Sherry AD. Paramagnetic lanthanide complexes as PARACEST agents for medical imaging. Chem Soc Rev. 2006;35:500-511.
-
(2006)
Chem Soc Rev
, vol.35
, pp. 500-511
-
-
Woods, M.1
Woessner, D.E.2
Sherry, A.D.3
-
245
-
-
33750071412
-
Sensitivity enhancement of multidimensional NMR experiments by paramagnetic relaxation effects
-
Cai S, Seu C, Kovacs Z, Sherry AD, Chen Y. Sensitivity enhancement of multidimensional NMR experiments by paramagnetic relaxation effects. J Am Chem Soc. 2006;128:13474-13478.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 13474-13478
-
-
Cai, S.1
Seu, C.2
Kovacs, Z.3
Sherry, A.D.4
Chen, Y.5
-
247
-
-
34247892289
-
1H-MRS as prognostic parameters in patients with non-small-cell lung cancer
-
1H-MRS as prognostic parameters in patients with non-small-cell lung cancer. J Magn Reson Imaging. 2007;25:992-999.
-
(2007)
J Magn Reson Imaging
, vol.25
, pp. 992-999
-
-
Yokota, H.1
Guo, J.2
Matoba, M.3
-
248
-
-
34547171180
-
1H NMR spectroscopy in conjunction with multivariate data analysis
-
1H NMR spectroscopy in conjunction with multivariate data analysis. J Proteome Res. 2007;6:2605-2614.
-
(2007)
J Proteome Res
, vol.6
, pp. 2605-2614
-
-
Yang, Y.1
Li, C.2
Nie, X.3
-
251
-
-
21144433425
-
MRS of oligodendroglial tumors: Correlation with histopathology and genetic subtypes
-
Jenkinson MD, Smith TS, Joyce K, et al. MRS of oligodendroglial tumors: correlation with histopathology and genetic subtypes. Neurology. 2005;64:2085-2089.
-
(2005)
Neurology
, vol.64
, pp. 2085-2089
-
-
Jenkinson, M.D.1
Smith, T.S.2
Joyce, K.3
-
252
-
-
0037189542
-
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
-
Lu H, Forbes RA, Verma A. Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis. J Biol Chem. 2002;277:23111-23115.
-
(2002)
J Biol Chem
, vol.277
, pp. 23111-23115
-
-
Lu, H.1
Forbes, R.A.2
Verma, A.3
-
253
-
-
0036347515
-
Lactate stimulates fibroblast expression of hyaluronan and CD44: The Warburg effect revisited
-
Stern R, Shuster S, Neudecker BA, Formby B. Lactate stimulates fibroblast expression of hyaluronan and CD44: the Warburg effect revisited. Exp Cell Res. 2002;276:24-31.
-
(2002)
Exp Cell Res
, vol.276
, pp. 24-31
-
-
Stern, R.1
Shuster, S.2
Neudecker, B.A.3
Formby, B.4
-
254
-
-
31544439615
-
99mTc-HMDP scintigraphy for the detection of bone metastases in patients with breast cancer
-
99mTc-HMDP scintigraphy for the detection of bone metastases in patients with breast cancer. Ann Nucl Med. 2005;19:573-579.
-
(2005)
Ann Nucl Med
, vol.19
, pp. 573-579
-
-
Abe, K.1
Sasaki, M.2
Kuwabara, Y.3
-
255
-
-
0030984978
-
Axillary lymph node metastases: Screening with [F-18]2-deoxy-2-fluoro-D-glucose (FDG) PET
-
Adler LP, Faulhaber PF, Schnur KC, et al. Axillary lymph node metastases: screening with [F-18]2-deoxy-2-fluoro-D-glucose (FDG) PET. Radiology. 1997;203:323-327.
-
(1997)
Radiology
, vol.203
, pp. 323-327
-
-
Adler, L.P.1
Faulhaber, P.F.2
Schnur, K.C.3
-
256
-
-
9544248690
-
Assessment of axillary lymph node involvement in breast cancer patients with positron emission tomography using radiolabeled 2-(fluorine-18)-fluoro-2-deoxy-D-glucose
-
Avril N, Dose J, Janicke F, et al. Assessment of axillary lymph node involvement in breast cancer patients with positron emission tomography using radiolabeled 2-(fluorine-18)-fluoro-2-deoxy-D-glucose. J Natl Cancer Inst. 1996;88:1204-1209.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1204-1209
-
-
Avril, N.1
Dose, J.2
Janicke, F.3
-
257
-
-
29144506286
-
The role of hybrid PET/CT in the evaluation of patients with cervical cancer
-
Amit A, Beck D, Lowenstein L, et al. The role of hybrid PET/CT in the evaluation of patients with cervical cancer. Gynecol Oncol. 2006;100:65-69.
-
(2006)
Gynecol Oncol
, vol.100
, pp. 65-69
-
-
Amit, A.1
Beck, D.2
Lowenstein, L.3
-
258
-
-
0035214254
-
The impact of FDG-PET on the management algorithm for recurrent colorectal cancer
-
Arulampalam T, Costa D, Visvikis D, et al. The impact of FDG-PET on the management algorithm for recurrent colorectal cancer. Eur J Nucl Med. 2001;28:1758-1765.
-
(2001)
Eur J Nucl Med
, vol.28
, pp. 1758-1765
-
-
Arulampalam, T.1
Costa, D.2
Visvikis, D.3
-
259
-
-
1842539580
-
FDG-PET for the pre-operative evaluation of colorectal liver metastases
-
Arulampalam TH, Francis DL, Visvikis D, et al. FDG-PET for the pre-operative evaluation of colorectal liver metastases. Eur J Surg Oncol. 2004;30:286-291.
-
(2004)
Eur J Surg Oncol
, vol.30
, pp. 286-291
-
-
Arulampalam, T.H.1
Francis, D.L.2
Visvikis, D.3
-
261
-
-
0031882858
-
Staging of primary colorectal carcinomas with fluorine-18 fluorodeoxyglucose whole-body PET: Correlation with histopathologic and CT findings
-
Abdel-Nabi H, Doerr RJ, Lamonica DM, et al. Staging of primary colorectal carcinomas with fluorine-18 fluorodeoxyglucose whole-body PET: correlation with histopathologic and CT findings. Radiology. 1998;206:755-760.
-
(1998)
Radiology
, vol.206
, pp. 755-760
-
-
Abdel-Nabi, H.1
Doerr, R.J.2
Lamonica, D.M.3
-
262
-
-
0031595329
-
18-FFDG PET with conventional imaging modalities (CT, MRI, US) in lymph node staging of head and neck cancer
-
18-FFDG PET with conventional imaging modalities (CT, MRI, US) in lymph node staging of head and neck cancer. Eur J Nucl Med. 1998;25:1255-1260.
-
(1998)
Eur J Nucl Med
, vol.25
, pp. 1255-1260
-
-
Adams, S.1
Baum, R.P.2
Stuckensen, T.3
-
263
-
-
34547905766
-
Detection of metastases in patients with cutaneous melanoma using FDG-PET/CT
-
Akcali C, Zincirkeser S, Erbagcy Z, et al. Detection of metastases in patients with cutaneous melanoma using FDG-PET/CT. J Int Med Res. 2007;35:547-553.
-
(2007)
J Int Med Res
, vol.35
, pp. 547-553
-
-
Akcali, C.1
Zincirkeser, S.2
Erbagcy, Z.3
-
267
-
-
0031664230
-
Fluorine-18 deoxyglucose positron emission tomography for the detection of bone metastases in patients with non-small cell lung cancer
-
Bury T, Barreto A, Daenen F, et al. Fluorine-18 deoxyglucose positron emission tomography for the detection of bone metastases in patients with non-small cell lung cancer. Eur J Nucl Med. 1998;25:1244-1247.
-
(1998)
Eur J Nucl Med
, vol.25
, pp. 1244-1247
-
-
Bury, T.1
Barreto, A.2
Daenen, F.3
-
268
-
-
34447571766
-
18F-FDG PET/CT in characterizing ovarian lesions and staging ovarian cancer: Correlation with transvaginal ultrasonography, computed tomography, and histology
-
18F-FDG PET/CT in characterizing ovarian lesions and staging ovarian cancer: correlation with transvaginal ultrasonography, computed tomography, and histology. Nucl Med Commun. 2007;28:589-595.
-
(2007)
Nucl Med Commun
, vol.28
, pp. 589-595
-
-
Castellucci, P.1
Perrone, A.M.2
Picchio, M.3
-
269
-
-
0038639067
-
18F-2-deoxyglucose positron emission tomography in patients with prostatespecific antigen relapse after treatment for localized prostate cancer
-
18F-2-deoxyglucose positron emission tomography in patients with prostatespecific antigen relapse after treatment for localized prostate cancer. Urol Int. 2003;70:311-315.
-
(2003)
Urol Int
, vol.70
, pp. 311-315
-
-
Chang, C.H.1
Wu, H.C.2
Tsai, J.J.3
-
270
-
-
34147187307
-
FDG PET in detecting primary and recurrent malignant salivary gland tumors
-
Cermik TF, Mavi A, Acikgoz G, et al. FDG PET in detecting primary and recurrent malignant salivary gland tumors. Clin Nucl Med. 2007;32:286-291.
-
(2007)
Clin Nucl Med
, vol.32
, pp. 286-291
-
-
Cermik, T.F.1
Mavi, A.2
Acikgoz, G.3
-
271
-
-
0141670441
-
18F]FDG PET in characterising renal cancer and detecting distant metastases: A comparison with CT
-
18F]FDG PET in characterising renal cancer and detecting distant metastases: a comparison with CT. Eur J Nucl Med Mol Imaging. 2003;30:1236-1245.
-
(2003)
Eur J Nucl Med Mol Imaging
, vol.30
, pp. 1236-1245
-
-
Aide, N.1
Cappele, O.2
Bottet, P.3
-
272
-
-
0141649403
-
18F-fluoro-2- deoxyglucose positron emission tomography: A preliminary report
-
18F-fluoro-2- deoxyglucose positron emission tomography: a preliminary report. Urol Int. 2003;71:306-309.
-
(2003)
Urol Int
, vol.71
, pp. 306-309
-
-
Chang, C.H.1
Shiau, Y.C.2
Shen, Y.Y.3
-
273
-
-
18844423748
-
Improvement in preoperative staging of gastric adenocarcinoma with positron emission tomography
-
Chen J, Cheong JH, Yun MJ, et al. Improvement in preoperative staging of gastric adenocarcinoma with positron emission tomography. Cancer. 2005;103:2383-2390.
-
(2005)
Cancer
, vol.103
, pp. 2383-2390
-
-
Chen, J.1
Cheong, J.H.2
Yun, M.J.3
-
274
-
-
0343527906
-
Improved detection of individual nodal involvement in squamous cell carcinoma of the esophagus by FDG PET
-
Choi JY, Lee KH, Shim YM, et al. Improved detection of individual nodal involvement in squamous cell carcinoma of the esophagus by FDG PET. J Nucl Med. 2000;41:808-815.
-
(2000)
J Nucl Med
, vol.41
, pp. 808-815
-
-
Choi, J.Y.1
Lee, K.H.2
Shim, Y.M.3
|