메뉴 건너뛰기




Volumn 120, Issue 7, 2007, Pages 1451-1458

HIF-1α and CA IX staining in invasive breast carcinomas: Prognosis and treatment outcome

Author keywords

Breast cancer; CA IX; HIF 1 ; Immunohistochemistry; Predictive factor; Prognosis

Indexed keywords

CARBONATE DEHYDRATASE IX; ESTROGEN RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROGESTERONE RECEPTOR; ANTINEOPLASTIC AGENT; CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE; HIF1A PROTEIN, HUMAN; HIF1A PROTEIN, MOUSE; TUMOR ANTIGEN; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 33847649279     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22436     Document Type: Article
Times cited : (207)

References (31)
  • 1
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia: A key regulatory factor in tumour growth
    • Harris AL. Hypoxia: a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 2
    • 0029753008 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit
    • Huang LE, Arany Z, Livingston DM, Bunn HF. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its α subunit. J Biol Chem 1996;271:32253-9.
    • (1996) J Biol Chem , vol.271 , pp. 32253-32259
    • Huang, L.E.1    Arany, Z.2    Livingston, D.M.3    Bunn, H.F.4
  • 4
    • 0030961006 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes
    • Salceda S, Caro J. Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. J Biol Chem 1997;272:22642-7.
    • (1997) J Biol Chem , vol.272 , pp. 22642-22647
    • Salceda, S.1    Caro, J.2
  • 6
    • 0033525830 scopus 로고    scopus 로고
    • Regulation of the hypoxia-inducible transcription factor 1 α by the ubiquitin-proteasome pathway
    • Kallio PJ, Wilson WJ, O'Brien S, Makino Y, Poellinger L. Regulation of the hypoxia-inducible transcription factor 1 α by the ubiquitin-proteasome pathway. J Biol Chem 1999;274:6519-25.
    • (1999) J Biol Chem , vol.274 , pp. 6519-6525
    • Kallio, P.J.1    Wilson, W.J.2    O'Brien, S.3    Makino, Y.4    Poellinger, L.5
  • 9
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL, Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003;3:721-32.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 11
    • 0032514685 scopus 로고    scopus 로고
    • Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes
    • Ivanov SV, Kuzmin I, Wei MH, Pack S, Geil L, Johnson BE, Stanbridge EJ, Lerman MI. Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes. Proc Natl Acad Sci USA 1998;95:12596-601.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12596-12601
    • Ivanov, S.V.1    Kuzmin, I.2    Wei, M.H.3    Pack, S.4    Geil, L.5    Johnson, B.E.6    Stanbridge, E.J.7    Lerman, M.I.8
  • 12
    • 0034024783 scopus 로고    scopus 로고
    • Human tumour-associated cell adhesion protein MN/CA IX: Identification of M75 epitope and of the region mediating cell adhesion
    • Zavada J, Zavadova Z, Pastorek J, Biesova Z, Jezek J, Velek J. Human tumour-associated cell adhesion protein MN/CA IX: identification of M75 epitope and of the region mediating cell adhesion. Br J Cancer 2000;82:1808-13.
    • (2000) Br J Cancer , vol.82 , pp. 1808-1813
    • Zavada, J.1    Zavadova, Z.2    Pastorek, J.3    Biesova, Z.4    Jezek, J.5    Velek, J.6
  • 15
    • 0036278899 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1 α is associated with an unfavorable prognosis in lymph node-positive breast cancer
    • for Austrian Breast and Colorectal Cancer Study Group
    • Schindl M, Schoppmann SF, Samonigg H, Hausmaninger H, Kwasny W, Gnant M, Jakesz R, Kubista E, Birner P, Oberhuber G, for Austrian Breast and Colorectal Cancer Study Group. Overexpression of hypoxia-inducible factor 1 α is associated with an unfavorable prognosis in lymph node-positive breast cancer. Clin Cancer Res 2002;8:1831-7.
    • (2002) Clin Cancer Res , vol.8 , pp. 1831-1837
    • Schindl, M.1    Schoppmann, S.F.2    Samonigg, H.3    Hausmaninger, H.4    Kwasny, W.5    Gnant, M.6    Jakesz, R.7    Kubista, E.8    Birner, P.9    Oberhuber, G.10
  • 19
    • 0141751743 scopus 로고    scopus 로고
    • The presence of a fibrotic focus in invasive breast carcinoma correlates with the expression of carbonic anhydrase IX and is a marker of hypoxia and poor prognosis
    • Colpaert CG, Vermeulen PB, Fox SB, Harris AL, Dirix LY, Van Marck EA. The presence of a fibrotic focus in invasive breast carcinoma correlates with the expression of carbonic anhydrase IX and is a marker of hypoxia and poor prognosis. Breast Cancer Res Treat 2003;81:137-47.
    • (2003) Breast Cancer Res Treat , vol.81 , pp. 137-147
    • Colpaert, C.G.1    Vermeulen, P.B.2    Fox, S.B.3    Harris, A.L.4    Dirix, L.Y.5    Van Marck, E.A.6
  • 21
    • 0043123069 scopus 로고    scopus 로고
    • Carbonic anhydrase-9 expression levels and prognosis in human breast cancer: Association with treatment outcome
    • Span PN, Bussink J, Manders P, Beex LV, Sweep CG. Carbonic anhydrase-9 expression levels and prognosis in human breast cancer: association with treatment outcome. Br J Cancer 2003;89:271-6.
    • (2003) Br J Cancer , vol.89 , pp. 271-276
    • Span, P.N.1    Bussink, J.2    Manders, P.3    Beex, L.V.4    Sweep, C.G.5
  • 22
    • 0642275613 scopus 로고    scopus 로고
    • aHIF but not HIF-1α transcript is a poor prognostic marker in human breast cancer
    • Cayre A, Rossignol F, Clottes E, Penault-Llorca F. aHIF but not HIF-1α transcript is a poor prognostic marker in human breast cancer. Breast Cancer Res 2003;5:R223-R230.
    • (2003) Breast Cancer Res , vol.5
    • Cayre, A.1    Rossignol, F.2    Clottes, E.3    Penault-Llorca, F.4
  • 24
    • 33646423829 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1α is a prognostic marker in premenopausal patients with intermediate to highly differentiated breast cancer but not a predictive marker for tamoxifen response
    • Kronblad A, Jirstrom K, Ryden L, Nordenskjold B, Landberg G. Hypoxia inducible factor-1α is a prognostic marker in premenopausal patients with intermediate to highly differentiated breast cancer but not a predictive marker for tamoxifen response. Int J Cancer 2006;118:2609-16.
    • (2006) Int J Cancer , vol.118 , pp. 2609-2616
    • Kronblad, A.1    Jirstrom, K.2    Ryden, L.3    Nordenskjold, B.4    Landberg, G.5
  • 25
    • 0041465022 scopus 로고    scopus 로고
    • HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia
    • Berra E, Benizri E, Ginouvès A, Volmat V, Roux D, Pouysségur J. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia. EMBO J 2003;22:4082-90.
    • (2003) EMBO J , vol.22 , pp. 4082-4090
    • Berra, E.1    Benizri, E.2    Ginouvès, A.3    Volmat, V.4    Roux, D.5    Pouysségur, J.6
  • 26
    • 0032725554 scopus 로고    scopus 로고
    • p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1α (HIF-1α) and enhance the transcriptional activity of HIF-1
    • Richard DE, Berra E, Gothié E, Roux D, Pouysségur J. p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1α (HIF-1α) and enhance the transcriptional activity of HIF-1. J Biol Chem 1999;274:32631-7.
    • (1999) J Biol Chem , vol.274 , pp. 32631-32637
    • Richard, D.E.1    Berra, E.2    Gothié, E.3    Roux, D.4    Pouysségur, J.5
  • 28
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown JM, Wilson WR, Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 2004;4:437-47.
    • (2004) Nat Rev Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 31
    • 0034759792 scopus 로고    scopus 로고
    • Hypoxia reduces hormone responsiveness of human breast cancer cells
    • Kurebayashi J, Otsuki T, Moriya T, Sonoo H. Hypoxia reduces hormone responsiveness of human breast cancer cells. Jpn J Cancer Res 2001;92:1093-101.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 1093-1101
    • Kurebayashi, J.1    Otsuki, T.2    Moriya, T.3    Sonoo, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.