-
1
-
-
27144488229
-
Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma
-
Achanta G., Sasaki R., Feng L., Carew J.S., Lu W., Pelicano H., Keating M.J., and Huang P. Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma. Eur. Mol. Biol. Org. J. 24 (2005) 3482-3492
-
(2005)
Eur. Mol. Biol. Org. J.
, vol.24
, pp. 3482-3492
-
-
Achanta, G.1
Sasaki, R.2
Feng, L.3
Carew, J.S.4
Lu, W.5
Pelicano, H.6
Keating, M.J.7
Huang, P.8
-
2
-
-
0036010219
-
Inhibitors of mitochondrial complex I attenuate the accumulation of hypoxia-inducible factor-1 during hypoxia in Hep3B cells
-
Agani F.H., Pichiule P., Carlos Chavez J., and LaManna J.C. Inhibitors of mitochondrial complex I attenuate the accumulation of hypoxia-inducible factor-1 during hypoxia in Hep3B cells. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 132 (2002) 107-109
-
(2002)
Comp. Biochem. Physiol. A Mol. Integr. Physiol.
, vol.132
, pp. 107-109
-
-
Agani, F.H.1
Pichiule, P.2
Carlos Chavez, J.3
LaManna, J.C.4
-
3
-
-
10744219705
-
Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes
-
Amatschek S., Koenig U., Auer H., Steinlein P., Pacher M., Gruenfelder A., Dekan G., Vogl S., Kubista E., Heider K.H., Stratowa C., Schreiber M., and Sommergruber W. Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes. Cancer Res. 64 (2004) 844-856
-
(2004)
Cancer Res.
, vol.64
, pp. 844-856
-
-
Amatschek, S.1
Koenig, U.2
Auer, H.3
Steinlein, P.4
Pacher, M.5
Gruenfelder, A.6
Dekan, G.7
Vogl, S.8
Kubista, E.9
Heider, K.H.10
Stratowa, C.11
Schreiber, M.12
Sommergruber, W.13
-
4
-
-
0032758657
-
Clear cell sarcoma of kidney in an adolescent and in young adults: a report of four cases with ultrastructural, immunohistochemical, and DNA flow cytometric analysis
-
Amin M.B., de Peralta-Venturina M.N., Ro J.Y., El-Naggar A., Mackay B., Ordonez N., Mani A., and Ayala A. Clear cell sarcoma of kidney in an adolescent and in young adults: a report of four cases with ultrastructural, immunohistochemical, and DNA flow cytometric analysis. Am. J. Surg. Pathol. 23 (1999) 1455-1463
-
(1999)
Am. J. Surg. Pathol.
, vol.23
, pp. 1455-1463
-
-
Amin, M.B.1
de Peralta-Venturina, M.N.2
Ro, J.Y.3
El-Naggar, A.4
Mackay, B.5
Ordonez, N.6
Mani, A.7
Ayala, A.8
-
5
-
-
0035901495
-
Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion
-
Amuthan G., Biswas G., Zhang S.Y., Klein-Szanto A., Vijayasarathy C., and Avadhani N.G. Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion. Eur. Mol. Biol. Org. J. 20 (2001) 1910-1920
-
(2001)
Eur. Mol. Biol. Org. J.
, vol.20
, pp. 1910-1920
-
-
Amuthan, G.1
Biswas, G.2
Zhang, S.Y.3
Klein-Szanto, A.4
Vijayasarathy, C.5
Avadhani, N.G.6
-
6
-
-
0037038669
-
Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells
-
Amuthan G., Biswas G., Ananadatheerthavarada H.K., Vijayasarathy C., Shephard H.M., and Avadhani N.G. Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells. Oncogene 21 (2002) 7839-7849
-
(2002)
Oncogene
, vol.21
, pp. 7839-7849
-
-
Amuthan, G.1
Biswas, G.2
Ananadatheerthavarada, H.K.3
Vijayasarathy, C.4
Shephard, H.M.5
Avadhani, N.G.6
-
7
-
-
24344471384
-
Role of mitochondria in the regulation of hypoxia-inducible factor-1alpha in the rat carotid body glomus cells
-
Baby S.M., Roy A., and Lahiri S. Role of mitochondria in the regulation of hypoxia-inducible factor-1alpha in the rat carotid body glomus cells. Histochem. Cell Biol. 124 (2005) 69-76
-
(2005)
Histochem. Cell Biol.
, vol.124
, pp. 69-76
-
-
Baby, S.M.1
Roy, A.2
Lahiri, S.3
-
8
-
-
22144493866
-
Negative and positive regulation of HIF-1: a complex network
-
Bardos J.I., and Ashcroft M. Negative and positive regulation of HIF-1: a complex network. Biochim. Biophys. Acta 1755 (2005) 107-120
-
(2005)
Biochim. Biophys. Acta
, vol.1755
, pp. 107-120
-
-
Bardos, J.I.1
Ashcroft, M.2
-
9
-
-
0034602950
-
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
-
Baysal B.E., Ferrell R.E., Willett-Brozick J.E., Lawrence E.C., Myssiorek D., Bosch A., van der Mey A., Taschner P.E., Rubinstein W.S., Myers E.N., Richard III C.W., Cornelisse C.J., Devilee P., and Devlin B. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. Science 287 (2000) 848-851
-
(2000)
Science
, vol.287
, pp. 848-851
-
-
Baysal, B.E.1
Ferrell, R.E.2
Willett-Brozick, J.E.3
Lawrence, E.C.4
Myssiorek, D.5
Bosch, A.6
van der Mey, A.7
Taschner, P.E.8
Rubinstein, W.S.9
Myers, E.N.10
Richard III, C.W.11
Cornelisse, C.J.12
Devilee, P.13
Devlin, B.14
-
10
-
-
0034803010
-
Phenotypic dichotomy in mitochondrial complex II genetic disorders
-
Baysal B.E., Rubinstein W.S., and Taschner P.E. Phenotypic dichotomy in mitochondrial complex II genetic disorders. J. Mol. Med. 79 (2001) 495-503
-
(2001)
J. Mol. Med.
, vol.79
, pp. 495-503
-
-
Baysal, B.E.1
Rubinstein, W.S.2
Taschner, P.E.3
-
11
-
-
23844456959
-
Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells
-
Behrend L., Mohr A., Dick T., and Zwacka R.M. Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells. Mol. Cell Biol. 25 (2005) 7758-7769
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 7758-7769
-
-
Behrend, L.1
Mohr, A.2
Dick, T.3
Zwacka, R.M.4
-
12
-
-
33646175288
-
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling
-
Berra E., Ginouves A., and Pouyssegur J. The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling. Eur. Mol. Biol. Org. Rep. 7 (2006) 41-45
-
(2006)
Eur. Mol. Biol. Org. Rep.
, vol.7
, pp. 41-45
-
-
Berra, E.1
Ginouves, A.2
Pouyssegur, J.3
-
13
-
-
0035109346
-
Mitochondrial genome instability in human cancers
-
Bianchi N.O., Bianchi M.S., and Richard S.M. Mitochondrial genome instability in human cancers. Mutat. Res. 488 (2001) 9-23
-
(2001)
Mutat. Res.
, vol.488
, pp. 9-23
-
-
Bianchi, N.O.1
Bianchi, M.S.2
Richard, S.M.3
-
14
-
-
13444256467
-
MITOMAP: a human mitochondrial genome database-2004 update
-
Brandon M.C., Lott M.T., Nguyen K.C., Spolim S., Navathe S.B., Baldi P., and Wallace D.C. MITOMAP: a human mitochondrial genome database-2004 update. Nucleic Acids Res. 33 (2005) D611-D613
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Brandon, M.C.1
Lott, M.T.2
Nguyen, K.C.3
Spolim, S.4
Navathe, S.B.5
Baldi, P.6
Wallace, D.C.7
-
15
-
-
0029394936
-
Hydrogen peroxide and the proliferation of BHK-21 cells
-
Burdon R.H., Alliangana D., and Gill V. Hydrogen peroxide and the proliferation of BHK-21 cells. Free Radic. Res. 23 (1995) 471-486
-
(1995)
Free Radic. Res.
, vol.23
, pp. 471-486
-
-
Burdon, R.H.1
Alliangana, D.2
Gill, V.3
-
16
-
-
0037204026
-
Serial analysis of gene expression in renal carcinoma cells reveals VHL-dependent sensitivity to TNFalpha cytotoxicity
-
Caldwell M.C., Hough C., Furer S., Linehan W.M., Morin P.J., and Gorospe M. Serial analysis of gene expression in renal carcinoma cells reveals VHL-dependent sensitivity to TNFalpha cytotoxicity. Oncogene 21 (2002) 929-936
-
(2002)
Oncogene
, vol.21
, pp. 929-936
-
-
Caldwell, M.C.1
Hough, C.2
Furer, S.3
Linehan, W.M.4
Morin, P.J.5
Gorospe, M.6
-
17
-
-
0037112360
-
The bioenergetic signature of cancer: a marker of tumor progression
-
Cuezva J.M., Krajewska M., de Heredia M.L., Krajewski S., Santamaria G., Kim H., Zapata J.M., Marusawa H., Chamorro M., and Reed J.C. The bioenergetic signature of cancer: a marker of tumor progression. Cancer Res. 62 (2002) 6674-6681
-
(2002)
Cancer Res.
, vol.62
, pp. 6674-6681
-
-
Cuezva, J.M.1
Krajewska, M.2
de Heredia, M.L.3
Krajewski, S.4
Santamaria, G.5
Kim, H.6
Zapata, J.M.7
Marusawa, H.8
Chamorro, M.9
Reed, J.C.10
-
18
-
-
3042820411
-
Renal cell carcinoma
-
Curti B.D. Renal cell carcinoma. J. Am. Med. Assoc. 292 (2004) 97-100
-
(2004)
J. Am. Med. Assoc.
, vol.292
, pp. 97-100
-
-
Curti, B.D.1
-
19
-
-
2642542967
-
Endogenous 2-oxoacids differentially regulate expression of oxygen sensors
-
Dalgard C.L., Lu H., Mohyeldin A., and Verma A. Endogenous 2-oxoacids differentially regulate expression of oxygen sensors. Biochem. J. 380 (2004) 419-424
-
(2004)
Biochem. J.
, vol.380
, pp. 419-424
-
-
Dalgard, C.L.1
Lu, H.2
Mohyeldin, A.3
Verma, A.4
-
21
-
-
0037611068
-
DNA mismatch repair genes in renal cell carcinoma
-
Deguchi M., Shiina H., Igawa M., Kaneuchi M., Nakajima K., and Dahiya R. DNA mismatch repair genes in renal cell carcinoma. J. Urol. 169 (2003) 2365-2371
-
(2003)
J. Urol.
, vol.169
, pp. 2365-2371
-
-
Deguchi, M.1
Shiina, H.2
Igawa, M.3
Kaneuchi, M.4
Nakajima, K.5
Dahiya, R.6
-
22
-
-
20444429105
-
Drugs targeting mitochondrial functions to control tumor cell growth
-
Dias N., and Bailly C. Drugs targeting mitochondrial functions to control tumor cell growth. Biochem Pharmacol 70 (2005) 1-12
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 1-12
-
-
Dias, N.1
Bailly, C.2
-
23
-
-
10644231741
-
The many faces of mitochondrial diseases
-
Di Mauro S. The many faces of mitochondrial diseases. Mitochondrion 4 (2004) 799-807
-
(2004)
Mitochondrion
, vol.4
, pp. 799-807
-
-
Di Mauro, S.1
-
24
-
-
0037364314
-
A role for mitochondrial enzymes in inherited neoplasia and beyond
-
Eng C., Kiuru M., Fernandez M.J., and Aaltonen L.A. A role for mitochondrial enzymes in inherited neoplasia and beyond. Nat. Rev. Cancer 3 (2003) 193-202
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 193-202
-
-
Eng, C.1
Kiuru, M.2
Fernandez, M.J.3
Aaltonen, L.A.4
-
25
-
-
0036400865
-
Hypoxic induction of hypoxia-inducible factor-1alpha and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells
-
Enomoto N., Koshikawa N., Gassmann M., Hayashi J., and Takenaga K. Hypoxic induction of hypoxia-inducible factor-1alpha and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells. Biochem. Biophys. Res. Commun. 297 (2002) 346-352
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.297
, pp. 346-352
-
-
Enomoto, N.1
Koshikawa, N.2
Gassmann, M.3
Hayashi, J.4
Takenaga, K.5
-
26
-
-
0030959772
-
Diagnostic significance of mitochondria in four types of renal epithelial neoplasms: an ultrastructural study of 60 tumors
-
Erlandson R.A., Shek T.W., and Reuter V.E. Diagnostic significance of mitochondria in four types of renal epithelial neoplasms: an ultrastructural study of 60 tumors. Ultrastruct. Pathol. 21 (1997) 409-417
-
(1997)
Ultrastruct. Pathol.
, vol.21
, pp. 409-417
-
-
Erlandson, R.A.1
Shek, T.W.2
Reuter, V.E.3
-
27
-
-
0029781664
-
Expression of oxidative phosphorylation genes in renal tumors and tumoral cell lines
-
Faure Vigny H., Heddi A., Giraud S., Chautard D., and Stepien G. Expression of oxidative phosphorylation genes in renal tumors and tumoral cell lines. Mol. Carcinog. 16 (1996) 165-172
-
(1996)
Mol. Carcinog.
, vol.16
, pp. 165-172
-
-
Faure Vigny, H.1
Heddi, A.2
Giraud, S.3
Chautard, D.4
Stepien, G.5
-
29
-
-
33745026994
-
-
Fruhwald, M.C., Hasselblatt, M., Wirth, S., Kohler, G., Schneppenheim, R., Subero, J.I., Siebert, R., Kordes, U., Jurgens, H., Vormoor, J., 2005, Non-linkage of familial rhabdoid tumors to SMARCB1 implies a second locus for the rhabdoid tumor predisposition syndrome. Pediatr. Blood Cancer.
-
-
-
-
30
-
-
21344455076
-
Losses of 1p and chromosome 14 in renal oncocytomas
-
Fuzesi L., Frank D., Nguyen C., Ringert R.H., Bartels H., and Gunawan B. Losses of 1p and chromosome 14 in renal oncocytomas. Cancer Genet. Cytogenet. 60 (2005) 120-125
-
(2005)
Cancer Genet. Cytogenet.
, vol.60
, pp. 120-125
-
-
Fuzesi, L.1
Frank, D.2
Nguyen, C.3
Ringert, R.H.4
Bartels, H.5
Gunawan, B.6
-
31
-
-
0037377756
-
von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arrays
-
Galban S., Fan J., Martindale J.L., Cheadle C., Hoffman B., Woods M.P., Temeles G., Brieger J., Decker J., and Gorospe M. von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arrays. Mol. Cell. Biol. 23 (2003) 2316-2328
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2316-2328
-
-
Galban, S.1
Fan, J.2
Martindale, J.L.3
Cheadle, C.4
Hoffman, B.5
Woods, M.P.6
Temeles, G.7
Brieger, J.8
Decker, J.9
Gorospe, M.10
-
32
-
-
2942511577
-
Recently elucidated energy catabolism pathways provide opportunities for novel treatments in hepatocellular carcinoma
-
Geschwind J.F., Georgiades C.S., Ko Y.H., and Pedersen P.L. Recently elucidated energy catabolism pathways provide opportunities for novel treatments in hepatocellular carcinoma. Expert Rev. Anticancer Ther. 4 (2004) 449-457
-
(2004)
Expert Rev. Anticancer Ther.
, vol.4
, pp. 449-457
-
-
Geschwind, J.F.1
Georgiades, C.S.2
Ko, Y.H.3
Pedersen, P.L.4
-
33
-
-
0027954044
-
Mutations of the VHL tumour suppressor gene in renal carcinoma
-
Gnarra J.R., Tory K., Weng Y., Schmidt L., Wei M.H., Li H., Latif F., Liu S., Chen F., Duh F.M., Lubensky I., Duan D.R., Florence C., Pozzatti R., Walther M.M., Bander N.H., Grossman H.B., Brauch H., Pomer S., Brooks J.D., Isaacs W.B., Lerman M.I., Zbar B., and Linehan W.M. Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat. Genet. 7 (1994) 85-90
-
(1994)
Nat. Genet.
, vol.7
, pp. 85-90
-
-
Gnarra, J.R.1
Tory, K.2
Weng, Y.3
Schmidt, L.4
Wei, M.H.5
Li, H.6
Latif, F.7
Liu, S.8
Chen, F.9
Duh, F.M.10
Lubensky, I.11
Duan, D.R.12
Florence, C.13
Pozzatti, R.14
Walther, M.M.15
Bander, N.H.16
Grossman, H.B.17
Brauch, H.18
Pomer, S.19
Brooks, J.D.20
Isaacs, W.B.21
Lerman, M.I.22
Zbar, B.23
Linehan, W.M.24
more..
-
34
-
-
17644426380
-
Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells
-
Gong Y., and Agani F.H. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells. Am. J. Physiol. Cell Physiol. 288 (2005) C1023-C1029
-
(2005)
Am. J. Physiol. Cell Physiol.
, vol.288
-
-
Gong, Y.1
Agani, F.H.2
-
35
-
-
0034190297
-
Protein kinase C signaling and oxidative stress
-
Gopalakrishna R., and Jaken S. Protein kinase C signaling and oxidative stress. Free Radic. Biol. Med. 28 (2000) 1349-1361
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 1349-1361
-
-
Gopalakrishna, R.1
Jaken, S.2
-
36
-
-
28544446058
-
Mitochondrial tumour suppressors: a genetic and biochemical update
-
Gottlieb E., and Tomlinson I.P. Mitochondrial tumour suppressors: a genetic and biochemical update. Nat. Rev. Cancer 11 (2005) 857-866
-
(2005)
Nat. Rev. Cancer
, vol.11
, pp. 857-866
-
-
Gottlieb, E.1
Tomlinson, I.P.2
-
37
-
-
0026275091
-
Cellular origin of renal cell carcinoma-an immunohistological study on monoclonal antibodies
-
Gu F.L., Cai S.L., Cai B.J., and Wu C.P. Cellular origin of renal cell carcinoma-an immunohistological study on monoclonal antibodies. Scand. J. Urol. Nephrol. 138 Suppl. (1991) 203-206
-
(1991)
Scand. J. Urol. Nephrol.
, vol.138
, Issue.SUPPL
, pp. 203-206
-
-
Gu, F.L.1
Cai, S.L.2
Cai, B.J.3
Wu, C.P.4
-
38
-
-
0029778997
-
A case of Pearson syndrome associated with multiple renal cysts
-
Gurgey A., Ozalp I., Rotig A., Coskun T., Tekinalp G., Erdem G., Akeoren Z., Caglar M., and Bakkaloglu A. A case of Pearson syndrome associated with multiple renal cysts. Pediatr. Nephrol. 10 (1996) 637-638
-
(1996)
Pediatr. Nephrol.
, vol.10
, pp. 637-638
-
-
Gurgey, A.1
Ozalp, I.2
Rotig, A.3
Coskun, T.4
Tekinalp, G.5
Erdem, G.6
Akeoren, Z.7
Caglar, M.8
Bakkaloglu, A.9
-
39
-
-
13844250595
-
Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression
-
Gwak G.Y., Yoon J.H., Kim K.M., Lee H.S., Chung J.W., and Gores G.J. Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression. J. Hepatol. 42 (2005) 358-364
-
(2005)
J. Hepatol.
, vol.42
, pp. 358-364
-
-
Gwak, G.Y.1
Yoon, J.H.2
Kim, K.M.3
Lee, H.S.4
Chung, J.W.5
Gores, G.J.6
-
40
-
-
16244418734
-
A new role for the von Hippel-Lindau tumor suppressor protein: stimulation of mitochondrial oxidative phosphorylation complex biogenesis
-
Hervouet E., Demont J., Pecina P., Vojtiskova A., Houstek J., Simonnet H., and Godinot C. A new role for the von Hippel-Lindau tumor suppressor protein: stimulation of mitochondrial oxidative phosphorylation complex biogenesis. Carcinogenesis 26 (2005) 531-539
-
(2005)
Carcinogenesis
, vol.26
, pp. 531-539
-
-
Hervouet, E.1
Demont, J.2
Pecina, P.3
Vojtiskova, A.4
Houstek, J.5
Simonnet, H.6
Godinot, C.7
-
41
-
-
0030030467
-
Novel mitochondrial DNA deletion found in a renal cell carcinoma
-
Horton T.M., Petros J.A., Heddi A., Shoffner J., Kaufman A.E., Graham Jr. S.D., Gramlich T., and Wallace D.C. Novel mitochondrial DNA deletion found in a renal cell carcinoma. Genes Chromosomes Cancer 15 (1996) 95-101
-
(1996)
Genes Chromosomes Cancer
, vol.15
, pp. 95-101
-
-
Horton, T.M.1
Petros, J.A.2
Heddi, A.3
Shoffner, J.4
Kaufman, A.E.5
Graham Jr., S.D.6
Gramlich, T.7
Wallace, D.C.8
-
42
-
-
21244488568
-
Congenital clear cell sarcoma of the kidney
-
Hung N.A. Congenital clear cell sarcoma of the kidney. Virchows Arch. 446 (2005) 566-568
-
(2005)
Virchows Arch.
, vol.446
, pp. 566-568
-
-
Hung, N.A.1
-
44
-
-
0037395395
-
Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways
-
Jiang Y., Zhang W., Kondo K., Klco J.M., St Martin T.B., Dufault M.R., Madden S.L., Kaelin Jr. W.G., and Nacht M. Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways. Mol. Cancer Res. 1 (2003) 453-462
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 453-462
-
-
Jiang, Y.1
Zhang, W.2
Kondo, K.3
Klco, J.M.4
St Martin, T.B.5
Dufault, M.R.6
Madden, S.L.7
Kaelin Jr., W.G.8
Nacht, M.9
-
45
-
-
22244440847
-
Proline hydroxylation and gene expression
-
Kaelin W.G. Proline hydroxylation and gene expression. Annu. Rev. Biochem. 74 (2005) 115-128
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 115-128
-
-
Kaelin, W.G.1
-
46
-
-
14644422657
-
Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes, and cancer
-
Kang D., and Hamasaki N. Alterations of mitochondrial DNA in common diseases and disease states: aging, neurodegeneration, heart failure, diabetes, and cancer. Curr. Med. Chem. 12 (2005) 429-441
-
(2005)
Curr. Med. Chem.
, vol.12
, pp. 429-441
-
-
Kang, D.1
Hamasaki, N.2
-
47
-
-
1542373685
-
Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
-
Kelly D.P., and Scarpulla R.C. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev. 18 (2004) 357-368
-
(2004)
Genes Dev.
, vol.18
, pp. 357-368
-
-
Kelly, D.P.1
Scarpulla, R.C.2
-
48
-
-
3343003878
-
Downregulation of Bcl-2 sensitises interferon-resistant renal cancer cells to Fas
-
Kelly J.D., Dai J., Eschwege P., Goldberg J.S., Duggan B.P., Williamson K.E., Bander N.H., and Nanus D.M. Downregulation of Bcl-2 sensitises interferon-resistant renal cancer cells to Fas. Br. J. Cancer 91 (2004) 164-170
-
(2004)
Br. J. Cancer
, vol.91
, pp. 164-170
-
-
Kelly, J.D.1
Dai, J.2
Eschwege, P.3
Goldberg, J.S.4
Duggan, B.P.5
Williamson, K.E.6
Bander, N.H.7
Nanus, D.M.8
-
49
-
-
4744341871
-
Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP
-
Ko Y.H., Smith B.L., Wang Y., Pomper M.G., Rini D.A., Torbenson M.S., Hullihen J., and Pedersen P.L. Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP. Biochem. Biophys. Res. Commun. 324 (2004) 269-275
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.324
, pp. 269-275
-
-
Ko, Y.H.1
Smith, B.L.2
Wang, Y.3
Pomper, M.G.4
Rini, D.A.5
Torbenson, M.S.6
Hullihen, J.7
Pedersen, P.L.8
-
50
-
-
0033828955
-
Renal oncocytoma with prominent intracytoplasmic vacuoles of mitochondrial origin
-
Koller A., Kain R., Haitel A., Mazal P.R., Asboth F., and Susani M. Renal oncocytoma with prominent intracytoplasmic vacuoles of mitochondrial origin. Histopathology 37 (2000) 264-268
-
(2000)
Histopathology
, vol.37
, pp. 264-268
-
-
Koller, A.1
Kain, R.2
Haitel, A.3
Mazal, P.R.4
Asboth, F.5
Susani, M.6
-
51
-
-
2342597973
-
Inhibition of HIF-2 alpha is sufficient to suppress pVHL-defective tumor growth
-
Kondo K., Kim W.Y., Lechpammer M., and Kaelin Jr. W.G. Inhibition of HIF-2 alpha is sufficient to suppress pVHL-defective tumor growth. PLoS Biol. 1 (2003) E83
-
(2003)
PLoS Biol.
, vol.1
-
-
Kondo, K.1
Kim, W.Y.2
Lechpammer, M.3
Kaelin Jr., W.G.4
-
52
-
-
0026664420
-
Mitochondrial and chromosomal DNA alterations in human chromophobe renal cell carcinomas
-
Kovacs A., Storkel S., Thoenes W., and Kovacs G. Mitochondrial and chromosomal DNA alterations in human chromophobe renal cell carcinomas. J. Pathol. 167 (1992) 273-277
-
(1992)
J. Pathol.
, vol.167
, pp. 273-277
-
-
Kovacs, A.1
Storkel, S.2
Thoenes, W.3
Kovacs, G.4
-
53
-
-
0031255567
-
The Heidelberg classification of renal cell tumours
-
Kovacs G., Akhtar M., Beckwith B.J., Bugert P., Cooper C.S., Delahunt B., Eble J.N., Fleming S., Ljungberg B., Medeiros L.J., Moch H., Reuter V.E., Ritz E., Roos G., Schmidt D., Srigley J.R., Storkel S., van den Berg E., and Zbar B. The Heidelberg classification of renal cell tumours. J. Pathol. 183 (1997) 131-133
-
(1997)
J. Pathol.
, vol.183
, pp. 131-133
-
-
Kovacs, G.1
Akhtar, M.2
Beckwith, B.J.3
Bugert, P.4
Cooper, C.S.5
Delahunt, B.6
Eble, J.N.7
Fleming, S.8
Ljungberg, B.9
Medeiros, L.J.10
Moch, H.11
Reuter, V.E.12
Ritz, E.13
Roos, G.14
Schmidt, D.15
Srigley, J.R.16
Storkel, S.17
van den Berg, E.18
Zbar, B.19
-
54
-
-
0036151647
-
Renal epithelial neoplasms: the diagnostic implications of electron microscopic study in 55 cases
-
Krishnan B., and Truong L.D. Renal epithelial neoplasms: the diagnostic implications of electron microscopic study in 55 cases. Hum. Pathol. 33 (2002) 68-79
-
(2002)
Hum. Pathol.
, vol.33
, pp. 68-79
-
-
Krishnan, B.1
Truong, L.D.2
-
55
-
-
2342586552
-
Resistance of rho(0) cells against apoptosis
-
Lee M.S., Kim J.Y., and Park S.Y. Resistance of rho(0) cells against apoptosis. Ann. NY Acad. Sci. 1011 (2004) 146-153
-
(2004)
Ann. NY Acad. Sci.
, vol.1011
, pp. 146-153
-
-
Lee, M.S.1
Kim, J.Y.2
Park, S.Y.3
-
57
-
-
16844366524
-
Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging
-
Lemasters J.J. Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging. Rejuv. Res. 8 (2005) 3-5
-
(2005)
Rejuv. Res.
, vol.8
, pp. 3-5
-
-
Lemasters, J.J.1
-
58
-
-
0242608613
-
The genetic basis of cancer of the kidney
-
Linehan W.M., Walther M.M., and Zbar B. The genetic basis of cancer of the kidney. J. Urol. 70 (2003) 2163-2172
-
(2003)
J. Urol.
, vol.70
, pp. 2163-2172
-
-
Linehan, W.M.1
Walther, M.M.2
Zbar, B.3
-
59
-
-
4644239258
-
Genetic basis of cancer of the kidney: disease-specific approaches to therapy
-
Linehan W.M., Vasselli J., Srinivasan R., Walther M.M., Merino M., Choyke P., Vocke C., Schmidt L., Isaacs J.S., Glenn G., Toro J., Zbar B., Bottaro D., and Neckers L. Genetic basis of cancer of the kidney: disease-specific approaches to therapy. Clin. Cancer Res. 10 (2004) 6282S-6289S
-
(2004)
Clin. Cancer Res.
, vol.10
-
-
Linehan, W.M.1
Vasselli, J.2
Srinivasan, R.3
Walther, M.M.4
Merino, M.5
Choyke, P.6
Vocke, C.7
Schmidt, L.8
Isaacs, J.S.9
Glenn, G.10
Toro, J.11
Zbar, B.12
Bottaro, D.13
Neckers, L.14
-
60
-
-
14644440800
-
The genetic basis of cancer of kidney cancer: implications for gene-specific clinical management
-
Linehan W.M., Grubb R.L., Coleman J.A., Zbar B., and Walther M. The genetic basis of cancer of kidney cancer: implications for gene-specific clinical management. BJU Int. 95 Suppl. 2 (2005) 2-7
-
(2005)
BJU Int.
, vol.95
, Issue.SUPPL. 2
, pp. 2-7
-
-
Linehan, W.M.1
Grubb, R.L.2
Coleman, J.A.3
Zbar, B.4
Walther, M.5
-
61
-
-
29644442625
-
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1
-
Lu H., Dalgard C., Mohyeldin A., McFate T., Tait A.S., and Verma A. Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. J. Biol. Chem. 280 (2005) 41928-41939
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 41928-41939
-
-
Lu, H.1
Dalgard, C.2
Mohyeldin, A.3
McFate, T.4
Tait, A.S.5
Verma, A.6
-
62
-
-
9744268261
-
Von Hippel-Lindau disease
-
Maher E.R. Von Hippel-Lindau disease. Curr. Mol. Med. 4 (2004) 833-842
-
(2004)
Curr. Mol. Med.
, vol.4
, pp. 833-842
-
-
Maher, E.R.1
-
63
-
-
9144268968
-
Solid renal tumor severity in von Hippel-Lindau disease is related to germline deletion length and location
-
Maranchie J.K., Afonso A., Albert P.S., Kalyandrug S., Phillips J.L., Zhou S., Peterson J., Ghadimi B.M., Hurley K., Riss J., Vasselli J.R., Ried T., Zbar B., Choyke P., Walther M.M., Klausner R.D., and Linehan W.M. Solid renal tumor severity in von Hippel-Lindau disease is related to germline deletion length and location. Hum. Mutat. 23 (2004) 40-46
-
(2004)
Hum. Mutat.
, vol.23
, pp. 40-46
-
-
Maranchie, J.K.1
Afonso, A.2
Albert, P.S.3
Kalyandrug, S.4
Phillips, J.L.5
Zhou, S.6
Peterson, J.7
Ghadimi, B.M.8
Hurley, K.9
Riss, J.10
Vasselli, J.R.11
Ried, T.12
Zbar, B.13
Choyke, P.14
Walther, M.M.15
Klausner, R.D.16
Linehan, W.M.17
-
64
-
-
0036260697
-
Cellular response to oxidative stress: signaling for suicide and survival
-
Martindale J.L., and Holbrook N.J. Cellular response to oxidative stress: signaling for suicide and survival. J. Cell Physiol. 192 (2002) 1-15
-
(2002)
J. Cell Physiol.
, vol.192
, pp. 1-15
-
-
Martindale, J.L.1
Holbrook, N.J.2
-
65
-
-
1642494855
-
2-deoxy-d-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo
-
Maschek G., Savaraj N., Priebe W., Braunschweiger P., Hamilton K., Tidmarsh G.F., De Young L.R., and Lampidis T.J. 2-deoxy-d-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo. Cancer Res. 64 (2004) 31-34
-
(2004)
Cancer Res.
, vol.64
, pp. 31-34
-
-
Maschek, G.1
Savaraj, N.2
Priebe, W.3
Braunschweiger, P.4
Hamilton, K.5
Tidmarsh, G.F.6
De Young, L.R.7
Lampidis, T.J.8
-
66
-
-
24344488419
-
The HIF pathway in cancer
-
Maxwell P.H. The HIF pathway in cancer. Semin. Cell Dev. Biol. 16 (2005) 523-530
-
(2005)
Semin. Cell Dev. Biol.
, vol.16
, pp. 523-530
-
-
Maxwell, P.H.1
-
67
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell P.H., Wiesener M.S., Chang G.W., Clifford S.C., Vaux E.C., Cockman M.E., Wykoff C.C., Pugh C.W., Maher E.R., and Ratcliffe P.J. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399 (1999) 271-275
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
68
-
-
0037837724
-
Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex
-
Maynard M.A., Qi H., Chung J., Lee E.H., Kondo Y., Hara S., Conaway R.C., Conaway J.W., and Ohh M. Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. J. Biol. Chem. 278 (2003) 11032-11040
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11032-11040
-
-
Maynard, M.A.1
Qi, H.2
Chung, J.3
Lee, E.H.4
Kondo, Y.5
Hara, S.6
Conaway, R.C.7
Conaway, J.W.8
Ohh, M.9
-
69
-
-
3042742575
-
Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma
-
Meierhofer D., Mayr J.A., Foetschl U., Berger A., Fink K., Schmeller N., Hacker G.W., Hauser-Kronberger C., Kofler B., and Sperl W. Decrease of mitochondrial DNA content and energy metabolism in renal cell carcinoma. Carcinogenesis 25 (2004) 1005-1010
-
(2004)
Carcinogenesis
, vol.25
, pp. 1005-1010
-
-
Meierhofer, D.1
Mayr, J.A.2
Foetschl, U.3
Berger, A.4
Fink, K.5
Schmeller, N.6
Hacker, G.W.7
Hauser-Kronberger, C.8
Kofler, B.9
Sperl, W.10
-
70
-
-
0037202189
-
Renal cancer: cytogenetic and molecular genetic aspects
-
Meloni-Ehrig A.M. Renal cancer: cytogenetic and molecular genetic aspects. Am. J. Med. Genet. 115 (2002) 164-172
-
(2002)
Am. J. Med. Genet.
, vol.115
, pp. 164-172
-
-
Meloni-Ehrig, A.M.1
-
71
-
-
20044376659
-
Downregulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significance
-
Mizutani Y., Nakanishi H., Yamamoto K., Li Y.N., Matsubara H., Mikami K., Okihara K., Kawauchi A., Bonavida B., and Miki T. Downregulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significance. J. Clin. Oncol. 23 (2005) 448-454
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 448-454
-
-
Mizutani, Y.1
Nakanishi, H.2
Yamamoto, K.3
Li, Y.N.4
Matsubara, H.5
Mikami, K.6
Okihara, K.7
Kawauchi, A.8
Bonavida, B.9
Miki, T.10
-
73
-
-
20044362590
-
Lifestyle factors, exposures, genetic susceptibility, and renal cell cancer risk: a review
-
Moore L.E., Wilson R.T., and Campleman S.L. Lifestyle factors, exposures, genetic susceptibility, and renal cell cancer risk: a review. Cancer Invest. 23 (2005) 240-255
-
(2005)
Cancer Invest.
, vol.23
, pp. 240-255
-
-
Moore, L.E.1
Wilson, R.T.2
Campleman, S.L.3
-
74
-
-
4644354183
-
Prognostic factors for survival of patients with stage IV renal cell carcinoma: memorial sloan-kettering cancer center experience
-
Motzer R.J., Bacik J., and Mazumdar M. Prognostic factors for survival of patients with stage IV renal cell carcinoma: memorial sloan-kettering cancer center experience. Clin. Cancer Res. 10 (2004) 6302S-6303S
-
(2004)
Clin. Cancer Res.
, vol.10
-
-
Motzer, R.J.1
Bacik, J.2
Mazumdar, M.3
-
75
-
-
0346243921
-
Concomitant loss of mitochondria and the DNA repair protein hOGG1 in clear cell carcinoma of the kidney
-
Mukunyadzi P., Huang H., Liu K., and Fan C.Y. Concomitant loss of mitochondria and the DNA repair protein hOGG1 in clear cell carcinoma of the kidney. Appl. Immunohistochem. Mol. Morphol. 11 (2003) 334-338
-
(2003)
Appl. Immunohistochem. Mol. Morphol.
, vol.11
, pp. 334-338
-
-
Mukunyadzi, P.1
Huang, H.2
Liu, K.3
Fan, C.Y.4
-
76
-
-
0036836501
-
Somatic mitochondrial DNA mutations in human chromophobe renal cell carcinomas
-
Nagy A., Wilhelm M., Sukosd F., Ljungberg B., and Kovacs G. Somatic mitochondrial DNA mutations in human chromophobe renal cell carcinomas. Genes Chromosom. Cancer 35 (2002) 256-260
-
(2002)
Genes Chromosom. Cancer
, vol.35
, pp. 256-260
-
-
Nagy, A.1
Wilhelm, M.2
Sukosd, F.3
Ljungberg, B.4
Kovacs, G.5
-
77
-
-
0037314430
-
Mutations of mtDNA in renal cell tumours arising in end-stage renal disease
-
Nagy A., Wilhelm M., and Kovacs G. Mutations of mtDNA in renal cell tumours arising in end-stage renal disease. J. Pathol. 199 (2003) 237-242
-
(2003)
J. Pathol.
, vol.199
, pp. 237-242
-
-
Nagy, A.1
Wilhelm, M.2
Kovacs, G.3
-
78
-
-
4143105824
-
Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations
-
Neumann H.P., Pawlu C., Peczkowska M., Bausch B., McWhinney S.R., Muresan M., Buchta M., Franke G., Klisch J., Bley T.A., Hoegerle S., Boedeker C.C., Opocher G., Schipper J., Januszewicz A., Eng C., and European-American Paraganglioma Study Group. Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations. J. Am. Med. Assoc. 292 (2004) 943-945
-
(2004)
J. Am. Med. Assoc.
, vol.292
, pp. 943-945
-
-
Neumann, H.P.1
Pawlu, C.2
Peczkowska, M.3
Bausch, B.4
McWhinney, S.R.5
Muresan, M.6
Buchta, M.7
Franke, G.8
Klisch, J.9
Bley, T.A.10
Hoegerle, S.11
Boedeker, C.C.12
Opocher, G.13
Schipper, J.14
Januszewicz, A.15
Eng, C.16
European-American Paraganglioma Study Group17
-
79
-
-
18044364791
-
Mechanism of the tumor suppressive effect of MnSOD overexpression
-
Oberley L.W. Mechanism of the tumor suppressive effect of MnSOD overexpression. Biomed. Pharmacother. 59 (2005) 143-148
-
(2005)
Biomed. Pharmacother.
, vol.59
, pp. 143-148
-
-
Oberley, L.W.1
-
80
-
-
26444488636
-
A molecular chaperone for mitochondrial complex I assembly is mutated in a progressive encephalopathy
-
Ogilvie I., Kennaway N.G., and Shoubridge E.A. A molecular chaperone for mitochondrial complex I assembly is mutated in a progressive encephalopathy. J. Clin. Invest. 115 (2005) 2784-2792
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2784-2792
-
-
Ogilvie, I.1
Kennaway, N.G.2
Shoubridge, E.A.3
-
81
-
-
0028169262
-
Formation of 8-hydroxy-2′-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in human renal-cell carcinoma
-
Okamoto K., Toyokuni S., Uchida K., Ogawa O., Takenewa J., Kakehi Y., Kinoshita H., Hattori-Nakakuki Y., Hiai H., and Yoshida O. Formation of 8-hydroxy-2′-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in human renal-cell carcinoma. Int. J. Cancer 58 (1994) 825-829
-
(1994)
Int. J. Cancer
, vol.58
, pp. 825-829
-
-
Okamoto, K.1
Toyokuni, S.2
Uchida, K.3
Ogawa, O.4
Takenewa, J.5
Kakehi, Y.6
Kinoshita, H.7
Hattori-Nakakuki, Y.8
Hiai, H.9
Yoshida, O.10
-
82
-
-
0037056002
-
Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention
-
Pedersen P.L., Mathupala S., Rempel A., Geschwind J.F., and Ko Y.H. Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention. Biochim. Biophys. Acta 1555 (2002) 14-20
-
(2002)
Biochim. Biophys. Acta
, vol.1555
, pp. 14-20
-
-
Pedersen, P.L.1
Mathupala, S.2
Rempel, A.3
Geschwind, J.F.4
Ko, Y.H.5
-
83
-
-
2942593991
-
ROS stress in cancer cells and therapeutic implications
-
Pelicano H., Carney D., and Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist. Updat. 7 (2004) 97-110
-
(2004)
Drug Resist. Updat.
, vol.7
, pp. 97-110
-
-
Pelicano, H.1
Carney, D.2
Huang, P.3
-
84
-
-
23944484674
-
Pediatric renal tumors: practical updates for the pathologist
-
Perlman E.J. Pediatric renal tumors: practical updates for the pathologist. Pediatr. Dev. Pathol. 8 (2005) 320-338
-
(2005)
Pediatr. Dev. Pathol.
, vol.8
, pp. 320-338
-
-
Perlman, E.J.1
-
85
-
-
20744445650
-
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
-
Raval R.R., Lau K.W., Tran M.G., Sowter H.M., Mandriota S.J., Li J.L., Pugh C.W., Maxwell P.H., Harris A.L., and Ratcliffe P.J. Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol. Cell Biol. 25 (2005) 5675-5686
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 5675-5686
-
-
Raval, R.R.1
Lau, K.W.2
Tran, M.G.3
Sowter, H.M.4
Mandriota, S.J.5
Li, J.L.6
Pugh, C.W.7
Maxwell, P.H.8
Harris, A.L.9
Ratcliffe, P.J.10
-
86
-
-
4444258772
-
Natural antisense transcripts of HIF-1alpha are conserved in rodents
-
Rossignol F., de Laplanche E., Mounier R., Bonnefont J., Cayre A., Godinot C., Simonnet H., and Clottes E. Natural antisense transcripts of HIF-1alpha are conserved in rodents. Gene 339 (2004) 121-130
-
(2004)
Gene
, vol.339
, pp. 121-130
-
-
Rossignol, F.1
de Laplanche, E.2
Mounier, R.3
Bonnefont, J.4
Cayre, A.5
Godinot, C.6
Simonnet, H.7
Clottes, E.8
-
87
-
-
0037362890
-
HIF hydroxylation and the mammalien oxygen-sensing pathway
-
Safran M., and Kaelin Jr. G. HIF hydroxylation and the mammalien oxygen-sensing pathway. J. Clin. Invest. 111 (2003) 779-783
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 779-783
-
-
Safran, M.1
Kaelin Jr., G.2
-
88
-
-
27144503330
-
Renal cell carcinoma in a pediatric patient with an inherited mitochondrial mutation
-
Sangkhathat S., Kusafuka T., Yoneda A., Kuroda S., Tanaka M., Sakai N., and Fukuzawa M. Renal cell carcinoma in a pediatric patient with an inherited mitochondrial mutation. Pediatr. Surg. Int. 21 (2005) 745-748
-
(2005)
Pediatr. Surg. Int.
, vol.21
, pp. 745-748
-
-
Sangkhathat, S.1
Kusafuka, T.2
Yoneda, A.3
Kuroda, S.4
Tanaka, M.5
Sakai, N.6
Fukuzawa, M.7
-
89
-
-
18144378426
-
A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1alpha
-
Sanjuan-Pla A., Cervera A.M., Apostolova N., Garcia-Bou R., Victor V.M., Murphy M.P., and McCreath K.J. A targeted antioxidant reveals the importance of mitochondrial reactive oxygen species in the hypoxic signaling of HIF-1alpha. Fed. Eur. Biochem. Soc. Lett. 579 (2005) 2669-2674
-
(2005)
Fed. Eur. Biochem. Soc. Lett.
, vol.579
, pp. 2669-2674
-
-
Sanjuan-Pla, A.1
Cervera, A.M.2
Apostolova, N.3
Garcia-Bou, R.4
Victor, V.M.5
Murphy, M.P.6
McCreath, K.J.7
-
90
-
-
0035838128
-
Differential expression of the subunits of the glucose-6-phosphatase system in the clear cell type of human renal cell carcinoma-no evidence for an overexpression of protein kinase B
-
Schmoll D., Balabanov S., Schwarck D., Burchell A., Kleist B., Zimmermann U., and Walther R. Differential expression of the subunits of the glucose-6-phosphatase system in the clear cell type of human renal cell carcinoma-no evidence for an overexpression of protein kinase B. Cancer Lett. 167 (2001) 85-90
-
(2001)
Cancer Lett.
, vol.167
, pp. 85-90
-
-
Schmoll, D.1
Balabanov, S.2
Schwarck, D.3
Burchell, A.4
Kleist, B.5
Zimmermann, U.6
Walther, R.7
-
91
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
-
Selak M.A., Armour S.M., MacKenzie E.D., Boulahbel H., Watson D.G., Mansfield K.D., Pan Y., Simon M.C., Thompson C.B., and Gottlieb E. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell. 7 (2005) 77-85
-
(2005)
Cancer Cell.
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
Pan, Y.7
Simon, M.C.8
Thompson, C.B.9
Gottlieb, E.10
-
92
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza G.L. Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3 (2003) 721-732
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
93
-
-
0024458411
-
A human adult Wilms' tumor. Histologic, ultrastructural, and cytogenetic analysis
-
Sherwood J.B., Bard R., Bhargava M., Burns E.R., and Iqbal M.A. A human adult Wilms' tumor. Histologic, ultrastructural, and cytogenetic analysis. Cancer Genet. Cytogenet. 42 (1989) 35-42
-
(1989)
Cancer Genet. Cytogenet.
, vol.42
, pp. 35-42
-
-
Sherwood, J.B.1
Bard, R.2
Bhargava, M.3
Burns, E.R.4
Iqbal, M.A.5
-
94
-
-
0034214361
-
The von Hippel-Lindau tumor suppressor targets to mitochondria
-
Shiao Y.H., Resau J.H., Nagashima K., Anderson L.M., and Ramakrishna G. The von Hippel-Lindau tumor suppressor targets to mitochondria. Cancer Res. 60 (2000) 2816-2819
-
(2000)
Cancer Res.
, vol.60
, pp. 2816-2819
-
-
Shiao, Y.H.1
Resau, J.H.2
Nagashima, K.3
Anderson, L.M.4
Ramakrishna, G.5
-
95
-
-
16444386967
-
-
Shidara, Y., Yamagata, K., Kanamori, T., Nakano, K., Kwong, J.Q., Manfredi, G., Oda, H., and Ohta, S., 2005. Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis. Cancer Res 65, 1655-1663.
-
-
-
-
96
-
-
0036262039
-
Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma
-
Simonnet H., Alazard N., Pfeiffer K., Gallou C., Beroud C., Demont J., Bouvier R., Schagger H., and Godinot C. Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma. Carcinogenesis 23 (2002) 759-768
-
(2002)
Carcinogenesis
, vol.23
, pp. 759-768
-
-
Simonnet, H.1
Alazard, N.2
Pfeiffer, K.3
Gallou, C.4
Beroud, C.5
Demont, J.6
Bouvier, R.7
Schagger, H.8
Godinot, C.9
-
97
-
-
0141814602
-
Mitochondrial complex I is deficient in renal oncocytomas
-
Simonnet H., Demont J., Pfeiffer K., Guenaneche L., Bouvier R., Brandt U., Schagger H., and Godinot C. Mitochondrial complex I is deficient in renal oncocytomas. Carcinogenesis 24 (2003) 1461-1466
-
(2003)
Carcinogenesis
, vol.24
, pp. 1461-1466
-
-
Simonnet, H.1
Demont, J.2
Pfeiffer, K.3
Guenaneche, L.4
Bouvier, R.5
Brandt, U.6
Schagger, H.7
Godinot, C.8
-
98
-
-
23644434087
-
Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis
-
Singh K.K., Kulawiec M., Still I., Desouki M.M., Geradts J., and Matsui S. Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis. Gene 354 (2005) 140-146
-
(2005)
Gene
, vol.354
, pp. 140-146
-
-
Singh, K.K.1
Kulawiec, M.2
Still, I.3
Desouki, M.M.4
Geradts, J.5
Matsui, S.6
-
100
-
-
0141988698
-
Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia
-
Sowter H.M., Raval R.R., Moore J.W., Ratcliffe P.J., and Harris A.L. Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. Cancer Res. 63 (2003) 6130-6134
-
(2003)
Cancer Res.
, vol.63
, pp. 6130-6134
-
-
Sowter, H.M.1
Raval, R.R.2
Moore, J.W.3
Ratcliffe, P.J.4
Harris, A.L.5
-
101
-
-
0026492106
-
Carbohydrate metabolism in human renal clear cell carcinomas
-
Steinberg P., Storkel S., Oesch F., and Thoenes W. Carbohydrate metabolism in human renal clear cell carcinomas. Lab. Invest. 67 (1992) 506-511
-
(1992)
Lab. Invest.
, vol.67
, pp. 506-511
-
-
Steinberg, P.1
Storkel, S.2
Oesch, F.3
Thoenes, W.4
-
102
-
-
0028265754
-
Analysis of nuclear and mitochondrial DNA alterations in thyroid and renal oncocytic tumors
-
Tallini G., Ladanyi M., Rosai J., and Jhanwar S.C. Analysis of nuclear and mitochondrial DNA alterations in thyroid and renal oncocytic tumors. Cytogenet. Cell Genet. 66 (1994) 253-259
-
(1994)
Cytogenet. Cell Genet.
, vol.66
, pp. 253-259
-
-
Tallini, G.1
Ladanyi, M.2
Rosai, J.3
Jhanwar, S.C.4
-
103
-
-
29744461227
-
Antitumor effect of parathyroid hormone-related protein neutralizing antibody in human renal cell carcinoma in vitro and in vivo
-
Talon I., Lindner V., Sourbier C., Schordan E., Rothhut S., Barthelmebs M., Lang H., Helwig J.J., and Massfelder T. Antitumor effect of parathyroid hormone-related protein neutralizing antibody in human renal cell carcinoma in vitro and in vivo. Carcinogenesis 27 (2006) 73-83
-
(2006)
Carcinogenesis
, vol.27
, pp. 73-83
-
-
Talon, I.1
Lindner, V.2
Sourbier, C.3
Schordan, E.4
Rothhut, S.5
Barthelmebs, M.6
Lang, H.7
Helwig, J.J.8
Massfelder, T.9
-
104
-
-
0033585496
-
aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia
-
Thrash-Bingham C.A., and Tartof K.D. aHIF: a natural antisense transcript overexpressed in human renal cancer and during hypoxia. J. Natl. Cancer Inst. 91 (1999) 143-151
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 143-151
-
-
Thrash-Bingham, C.A.1
Tartof, K.D.2
-
105
-
-
0033839840
-
Ultrastructural observations on mitochondria and microvesicles in renal oncocytoma, chromophobe renal cell carcinoma, and eosinophilic variant of conventional (clear cell) renal cell carcinoma
-
Tickoo S.K., Lee M.W., Eble J.N., Amin M., Christopherson T., Zarbo R.J., and Amin M.B. Ultrastructural observations on mitochondria and microvesicles in renal oncocytoma, chromophobe renal cell carcinoma, and eosinophilic variant of conventional (clear cell) renal cell carcinoma. Am. J. Surg. Pathol. 24 (2000) 1247-1256
-
(2000)
Am. J. Surg. Pathol.
, vol.24
, pp. 1247-1256
-
-
Tickoo, S.K.1
Lee, M.W.2
Eble, J.N.3
Amin, M.4
Christopherson, T.5
Zarbo, R.J.6
Amin, M.B.7
-
106
-
-
18544365990
-
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
-
Tomlinson I.P., Alam N.A., Rowan A.J., Barclay E., Jaeger E.E., Kelsell D., Leigh I., Gorman P., Lamlum H., Rahman S., Roylance R.R., Olpin S., Bevan S., Barker K., Hearle N., Houlston R.S., Kiuru M., Lehtonen R., Karhu A., Vilkki S., Laiho P., Eklund C., Vierimaa O., Aittomaki K., Hietala M., Sistonen P., Paetau A., Salovaara R., Herva R., Launonen V., and Aaltonen L.A. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat. Genet. 30 (2002) 406-410
-
(2002)
Nat. Genet.
, vol.30
, pp. 406-410
-
-
Tomlinson, I.P.1
Alam, N.A.2
Rowan, A.J.3
Barclay, E.4
Jaeger, E.E.5
Kelsell, D.6
Leigh, I.7
Gorman, P.8
Lamlum, H.9
Rahman, S.10
Roylance, R.R.11
Olpin, S.12
Bevan, S.13
Barker, K.14
Hearle, N.15
Houlston, R.S.16
Kiuru, M.17
Lehtonen, R.18
Karhu, A.19
Vilkki, S.20
Laiho, P.21
Eklund, C.22
Vierimaa, O.23
Aittomaki, K.24
Hietala, M.25
Sistonen, P.26
Paetau, A.27
Salovaara, R.28
Herva, R.29
Launonen, V.30
Aaltonen, L.A.31
more..
-
107
-
-
0042861598
-
Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect
-
Unwin R.D., Craven R.A., Harnden P., Hanrahan S., Totty N., Knowles M., Eardley I., Selby P.J., and Banks R.E. Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect. Proteomics (2003) 1620-1632
-
(2003)
Proteomics
, pp. 1620-1632
-
-
Unwin, R.D.1
Craven, R.A.2
Harnden, P.3
Hanrahan, S.4
Totty, N.5
Knowles, M.6
Eardley, I.7
Selby, P.J.8
Banks, R.E.9
-
108
-
-
23844434673
-
AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cell
-
Urbano A., Lakshmanan U., Choo P.H., Kwan J.C., Ng P.Y., Guo K., Dhakshinamoorthy S., and Porter A. AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cell. Eur. Mol. Biol. Org. J. 24 (2005) 2815-2826
-
(2005)
Eur. Mol. Biol. Org. J.
, vol.24
, pp. 2815-2826
-
-
Urbano, A.1
Lakshmanan, U.2
Choo, P.H.3
Kwan, J.C.4
Ng, P.Y.5
Guo, K.6
Dhakshinamoorthy, S.7
Porter, A.8
-
110
-
-
0035880239
-
Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain
-
Vaux E.C., Metzen E., Yeates K.M., and Ratcliffe P.J. Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. Blood 98 (2001) 296-302
-
(2001)
Blood
, vol.98
, pp. 296-302
-
-
Vaux, E.C.1
Metzen, E.2
Yeates, K.M.3
Ratcliffe, P.J.4
-
111
-
-
0035874947
-
VHL and FHIT loss of heterozygosity is common in all renal cancer morphotypes but differs in pattern and prognostic significance
-
Velickovic M., Delahunt B., Storkel S., and Grebem S.K. VHL and FHIT loss of heterozygosity is common in all renal cancer morphotypes but differs in pattern and prognostic significance. Cancer Res. 61 (2001) 4815-4819
-
(2001)
Cancer Res.
, vol.61
, pp. 4815-4819
-
-
Velickovic, M.1
Delahunt, B.2
Storkel, S.3
Grebem, S.K.4
-
112
-
-
0036097950
-
Intragenic PTEN/MMAC1 loss of heterozygosity in conventional (clear-cell) renal cell carcinoma is associated with poor patient prognosis
-
Velickovic M., Delahunt B., McIver B., and Grebe S.K. Intragenic PTEN/MMAC1 loss of heterozygosity in conventional (clear-cell) renal cell carcinoma is associated with poor patient prognosis. Mod. Pathol. 15 (2002) 479-485
-
(2002)
Mod. Pathol.
, vol.15
, pp. 479-485
-
-
Velickovic, M.1
Delahunt, B.2
McIver, B.3
Grebe, S.K.4
-
113
-
-
27144528747
-
Human mitochondrial complex I assembly is mediated by NDUFAF1
-
Vogel R.O., Janssen R.J., Ugalde C., Grovenstein M., Huijbens R.J., Visch H.J., van den Heuvel L.P., Willems P.H., Zeviani M., Smeitink J.A., and Nijtmans L.G. Human mitochondrial complex I assembly is mediated by NDUFAF1. Fed. Eur. Biochem. Soc. J. 272 (2005) 5317-5326
-
(2005)
Fed. Eur. Biochem. Soc. J.
, vol.272
, pp. 5317-5326
-
-
Vogel, R.O.1
Janssen, R.J.2
Ugalde, C.3
Grovenstein, M.4
Huijbens, R.J.5
Visch, H.J.6
van den Heuvel, L.P.7
Willems, P.H.8
Zeviani, M.9
Smeitink, J.A.10
Nijtmans, L.G.11
-
114
-
-
17144416530
-
Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells
-
Wang V., Davis D.A., Haque M., Huang L.E., and Yarchoan R. Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells. Cancer Res. 65 (2005) 3299-3306
-
(2005)
Cancer Res.
, vol.65
, pp. 3299-3306
-
-
Wang, V.1
Davis, D.A.2
Haque, M.3
Huang, L.E.4
Yarchoan, R.5
-
115
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science 123 (1956) 309-314
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
116
-
-
0001768994
-
-
Warburg O. (Ed), Constable and Co., London
-
Warburg O., Wind F., and Neglers E. In: Warburg O. (Ed). Metabolism of Tumours (1930), Constable and Co., London 254-270
-
(1930)
Metabolism of Tumours
, pp. 254-270
-
-
Warburg, O.1
Wind, F.2
Neglers, E.3
-
118
-
-
31444444162
-
Integration of oxygen signaling at the consensus HRE
-
Wenger R.H., Stehl D.P., and Camenish G. Integration of oxygen signaling at the consensus HRE. Sci. STKE 306 (2005) 12
-
(2005)
Sci. STKE
, vol.306
, pp. 12
-
-
Wenger, R.H.1
Stehl, D.P.2
Camenish, G.3
-
119
-
-
1942533531
-
Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene
-
Wykoff C.C., Sotiriou C., Cockman M.E., Ratcliffe P.J., Maxwell P., Liu E., and Harris A.L. Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene. Br. J. Cancer 90 (2004) 1235-1244
-
(2004)
Br. J. Cancer
, vol.90
, pp. 1235-1244
-
-
Wykoff, C.C.1
Sotiriou, C.2
Cockman, M.E.3
Ratcliffe, P.J.4
Maxwell, P.5
Liu, E.6
Harris, A.L.7
-
120
-
-
6944247736
-
Disturbed balance of expression between XIAP and Smac/DIABLO during tumour progression in renal cell carcinomas
-
Yan Y., Mahotka C., Heikaus S., Shibata T., Wethkamp N., Liebmann J., Suschek C.V., Guo Y., Gabbert H.E., Gerharz C.D., and Ramp U. Disturbed balance of expression between XIAP and Smac/DIABLO during tumour progression in renal cell carcinomas. Br. J. Cancer 91 (2004) 1349-1357
-
(2004)
Br. J. Cancer
, vol.91
, pp. 1349-1357
-
-
Yan, Y.1
Mahotka, C.2
Heikaus, S.3
Shibata, T.4
Wethkamp, N.5
Liebmann, J.6
Suschek, C.V.7
Guo, Y.8
Gabbert, H.E.9
Gerharz, C.D.10
Ramp, U.11
-
121
-
-
4644229716
-
Bevacizumab for patients with metastatic renal cancer: an update
-
Yang J.C. Bevacizumab for patients with metastatic renal cancer: an update. Clin. Cancer Res. 10 (2004) 6367S-6370S
-
(2004)
Clin. Cancer Res.
, vol.10
-
-
Yang, J.C.1
-
122
-
-
21344446106
-
-
Yang, X.J., Tan, M.H., Kim, H.L., Ditlev, J.A., Betten, M.W., Png, C.E., Kort, E.J., Futami, K., Furge, K.A., Takahashi, M., Kanayama, H.O., Tan, P.H., Teh, B.S., Luan, C., Wang, K., Pins, M., Tretiakova, M., Anema, J., Kahnoski, R., Nicol, T., Stadler, W., Vogelzang, N.G., Amato, R., Seligson, D., Figlin, R., Belldegrun, A., Rogers, C.G., Teh, B.T., 2005. A molecular classification of papillary renal cell carcinoma. Cancer Res 65, 5628-5637.
-
-
-
-
123
-
-
11144222884
-
Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression
-
Yoshimura H., Dhar D.K., Kohno H., Kubota H., Fujii T., Ueda S., Kinugasa S., Tachibana M., and Nagasue N. Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression. Clin. Cancer Res. 10 (2004) 8554-8560
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 8554-8560
-
-
Yoshimura, H.1
Dhar, D.K.2
Kohno, H.3
Kubota, H.4
Fujii, T.5
Ueda, S.6
Kinugasa, S.7
Tachibana, M.8
Nagasue, N.9
-
124
-
-
0032869860
-
Histopathology and molecular genetics of renal tumors toward unification of a classification system
-
Zambrano N.R., Lubensky I.A., Merino M.J., Linehan W.M., and Walther M.M. Histopathology and molecular genetics of renal tumors toward unification of a classification system. J. Urol. 162 (1999) 1246-1258
-
(1999)
J. Urol.
, vol.162
, pp. 1246-1258
-
-
Zambrano, N.R.1
Lubensky, I.A.2
Merino, M.J.3
Linehan, W.M.4
Walther, M.M.5
-
125
-
-
1442324401
-
Renal oncocytomas with rearrangements involving 11q13 contain breakpoints near CCND1
-
Zanssen S., Gunawan B., Fuzesi L., Warburton D., and Schon E.A. Renal oncocytomas with rearrangements involving 11q13 contain breakpoints near CCND1. Cancer Genet. Cytogenet. 149 (2004) 120-124
-
(2004)
Cancer Genet. Cytogenet.
, vol.149
, pp. 120-124
-
-
Zanssen, S.1
Gunawan, B.2
Fuzesi, L.3
Warburton, D.4
Schon, E.A.5
|