-
1
-
-
0035500410
-
Apoptosis and cancer chemotherapy
-
Makin G, Dive C: Apoptosis and cancer chemotherapy. Trends Cell Biol. 2001, 11:S22-6
-
(2001)
Trends Cell Biol.
, vol.11
-
-
Makin, G.1
Dive, C.2
-
2
-
-
0028286119
-
v-raf suppresses apoptosis and promotes growth of interleukin-3-dependent myeloid cells
-
Cleveland JL, Troppmair J, Packham G, Askew DS, Lloyd P, Gonzalez-Garcia M, Nunez G, Ihle JN, Rapp UR: v-raf suppresses apoptosis and promotes growth of interleukin-3-dependent myeloid cells. Oncogene. 1994, 9:2217-26
-
(1994)
Oncogene
, vol.9
, pp. 2217-2226
-
-
Cleveland, J.L.1
Troppmair, J.2
Packham, G.3
Askew, D.S.4
Lloyd, P.5
Gonzalez-Garcia, M.6
Nunez, G.7
Ihle, J.N.8
Rapp, U.R.9
-
3
-
-
0345498292
-
Bcl-2 targets the protein kinase Raf-1 to mitochondria
-
Wang HG, Rapp UR, Reed JC: Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell. 1996, 87:629-38
-
(1996)
Cell
, vol.87
, pp. 629-638
-
-
Wang, H.G.1
Rapp, U.R.2
Reed, J.C.3
-
4
-
-
0035146138
-
Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons
-
Wiese S, Pei G, Karch C, Troppmair J, Holtmann B, Rapp UR, Sendtner M: Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons. Nat Neurosci. 2001, 4:137-42
-
(2001)
Nat. Neurosci.
, vol.4
, pp. 137-142
-
-
Wiese, S.1
Pei, G.2
Karch, C.3
Troppmair, J.4
Holtmann, B.5
Rapp, U.R.6
Sendtner, M.7
-
5
-
-
0035871383
-
Analysis of the transcriptional program induced by Raf in epithelial cells
-
Schulze A, Lehmann K, Jefferies HB, McMahon M, Downward J: Analysis of the transcriptional program induced by Raf in epithelial cells. Genes Dev. 2001, 15:981-94
-
(2001)
Genes Dev.
, vol.15
, pp. 981-994
-
-
Schulze, A.1
Lehmann, K.2
Jefferies, H.B.3
McMahon, M.4
Downward, J.5
-
6
-
-
0035102807
-
Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals
-
von Gise A, Lorenz P, Wellbrock C, Hemmings B, Berberich-Siebelt F, Rapp UR, Troppmair J: Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals. Mol Cell Biol. 2001, 21:2324-36
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 2324-2336
-
-
von Gise, A.1
Lorenz, P.2
Wellbrock, C.3
Hemmings, B.4
Berberich-Siebelt, F.5
Rapp, U.R.6
Troppmair, J.7
-
7
-
-
0035854747
-
Anti-apoptotic Signaling of the Insulin-like Growth Factor-I Receptor through Mitochondrial Translocation of c-Raf and Nedd4
-
Peruzzi F, Prisco M, Morrione A, Valentinis B, Baserga R: Anti-apoptotic Signaling of the Insulin-like Growth Factor-I Receptor through Mitochondrial Translocation of c-Raf and Nedd4. J Biol Chem 2001, 276:25990-6
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25990-25996
-
-
Peruzzi, F.1
Prisco, M.2
Morrione, A.3
Valentinis, B.4
Baserga, R.5
-
8
-
-
0035833318
-
Independent control of cell survival by Raf-1 and Bcl-2 at the mitochondria
-
Zhong J, Troppmair J, Rapp UR: Independent control of cell survival by Raf-1 and Bcl-2 at the mitochondria. Oncogene. 2001, 20:4807-16
-
(2001)
Oncogene
, vol.20
, pp. 4807-4816
-
-
Zhong, J.1
Troppmair, J.2
Rapp, U.R.3
-
9
-
-
0032514363
-
Activation of NF-kappa B by oncogenic Raf in HEK 293 cells occurs through autocrine recruitment of the stress kinase cascade
-
Troppmair J, Hartkamp J, Rapp UR: Activation of NF-kappa B by oncogenic Raf in HEK 293 cells occurs through autocrine recruitment of the stress kinase cascade. Oncogene. 1998, 17:685-90
-
(1998)
Oncogene
, vol.17
, pp. 685-690
-
-
Troppmair, J.1
Hartkamp, J.2
Rapp, U.R.3
-
10
-
-
12944305960
-
Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation
-
Baumann B, Weber CK, Troppmair J, Whiteside S, Israel A, Rapp UR, Wirth T: Raf induces NF-kappaB by membrane shuttle kinase MEKK1, a signaling pathway critical for transformation. Proc Natl Acad Sci U S A. 2000, 97:4615-20
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 4615-4620
-
-
Baumann, B.1
Weber, C.K.2
Troppmair, J.3
Whiteside, S.4
Israel, A.5
Rapp, U.R.6
Wirth, T.7
-
11
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD: The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997, 275:1132-6
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
12
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng TI, Jones DP, Wang X: Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science. 1997, 275:1129-32
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.I.7
Jones, D.P.8
Wang, X.9
-
13
-
-
9844257587
-
Inhibition of Bax channel-forming activity by Bcl-2
-
Antonsson B, Conti F, Ciavatta A, Montessuit S, Lewis S, Martinou I, Bernasconi L, Bernard A, Mermod JJ, Mazzei G, Maundrell K, Gambale F, Sadoul R, Martinou J: Inhibition of Bax channel-forming activity by Bcl-2. Science. 1997, 277:370-2
-
(1997)
Science
, vol.277
, pp. 370-372
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
Montessuit, S.4
Lewis, S.5
Martinou, I.6
Bernasconi, L.7
Bernard, A.8
Mermod, J.J.9
Mazzei, G.10
Maundrell, K.11
Gambale, F.12
Sadoul, R.13
Martinou, J.14
-
14
-
-
0033519705
-
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
-
Shimizu S, Narita M, Tsujimoto Y: Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature. 1999,399:483-7.
-
(1999)
Nature
, vol.399
, pp. 483-487
-
-
Shimizu, S.1
Narita, M.2
Tsujimoto, Y.3
-
15
-
-
0034724190
-
BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death
-
Shimizu S, Konishi A, Kodama T, Tsujimoto Y: BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death. Natl Acad Sci U S A. 2000, 97:3100-5
-
(2000)
Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 3100-3105
-
-
Shimizu, S.1
Konishi, A.2
Kodama, T.3
Tsujimoto, Y.4
-
16
-
-
0032526544
-
Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant
-
Salomoni P, Wasik MA, Riedel RF, Reiss K, Choi JK, Skorski T, Calabretta B: Expression of constitutively active Raf-1 in the mitochondria restores antiapoptotic and leukemogenic potential of a transformation-deficient BCR/ABL mutant. J Exp Med. 1998, 187:1995-2007
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1995-2007
-
-
Salomoni, P.1
Wasik, M.A.2
Riedel, R.F.3
Reiss, K.4
Choi, J.K.5
Skorski, T.6
Calabretta, B.7
-
17
-
-
0022110323
-
A yeast mutant temperature-sensitive for mitochondrial assembly is deficient in a mitochondrial protease activity that cleaves imported precursor polypeptides
-
Yaffe MP, Ohta S, Schatz G: A yeast mutant temperature-sensitive for mitochondrial assembly is deficient in a mitochondrial protease activity that cleaves imported precursor polypeptides. Embo J 1985, 4:2069-74
-
(1985)
Embo J.
, vol.4
, pp. 2069-2074
-
-
Yaffe, M.P.1
Ohta, S.2
Schatz, G.3
-
18
-
-
0026596576
-
Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase
-
Bruder JT, Heidecker G, Rapp UR: Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase. Genes Dev. 1992, 6:545-56
-
(1992)
Genes Dev.
, vol.6
, pp. 545-556
-
-
Bruder, J.T.1
Heidecker, G.2
Rapp, U.R.3
-
19
-
-
0034989234
-
The Ras-Raf relationship: An unfinished puzzle
-
Kerkhoff E, Rapp UR: The Ras-Raf relationship: an unfinished puzzle. Adv Enzyme Regul. 2001, 41:261-7
-
(2001)
Adv. Enzyme Regul.
, vol.41
, pp. 261-267
-
-
Kerkhoff, E.1
Rapp, U.R.2
-
20
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
Budihardjo I, Oliver H, Lutter M, Luo X, Wang X: Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol. 1999, 15:269-90
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 269-290
-
-
Budihardjo, I.1
Oliver, H.2
Lutter, M.3
Luo, X.4
Wang, X.5
-
21
-
-
0028341536
-
Permeation of hydrophilic solutes through mitochondrial outer membranes: Review on mitochondrial porins
-
Benz R: Permeation of hydrophilic solutes through mitochondrial outer membranes: review on mitochondrial porins. Biochim Biophys Acta. 1994, 1197:167-96
-
(1994)
Biochim. Biophys. Acta
, vol.1197
, pp. 167-196
-
-
Benz, R.1
-
22
-
-
0032550363
-
The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins
-
Marzo I, Brenner C, Zamzami N, Susin SA, Beutner G, Brdiczka D, Remy R, Xie ZH, Reed JC, Kroemer G: The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins. J Exp Med. 1998, 187:1261-71
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1261-1271
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
Susin, S.A.4
Beutner, G.5
Brdiczka, D.6
Remy, R.7
Xie, Z.H.8
Reed, J.C.9
Kroemer, G.10
-
23
-
-
0031008145
-
Role of the mitochondrial permeability transition pore in apoptosis
-
Hirsch T, Marzo I, Kroemer G: Role of the mitochondrial permeability transition pore in apoptosis. Biosci Rep. 1997, 17:67-76
-
(1997)
Biosci. Rep.
, vol.17
, pp. 67-76
-
-
Hirsch, T.1
Marzo, I.2
Kroemer, G.3
-
24
-
-
0029862706
-
Mitochondrial control of nuclear apoptosis
-
Zamzami N, Susin SA, Marchetti P, Hirsch T, Gomez-Monterrey I, Castedo M, Kroemer G: Mitochondrial control of nuclear apoptosis. J Exp Med. 1996, 183:1533-44
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1533-1544
-
-
Zamzami, N.1
Susin, S.A.2
Marchetti, P.3
Hirsch, T.4
Gomez-Monterrey, I.5
Castedo, M.6
Kroemer, G.7
-
25
-
-
0034697365
-
Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c
-
Shimizu S, Ide T, Yanagida T, Tsujimoto Y: Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c. J Biol Chem. 2000, 275:12321-5
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12321-12325
-
-
Shimizu, S.1
Ide, T.2
Yanagida, T.3
Tsujimoto, Y.4
-
26
-
-
0035931765
-
Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells
-
Shimizu S, Matsuoka Y, Shinohara Y, Yoneda Y, Tsujimoto Y: Essential role of voltage-dependent anion channel in various forms of apoptosis in mammalian cells. J Cell Biol. 2001, 152:237-50
-
(2001)
J. Cell Biol.
, vol.152
, pp. 237-250
-
-
Shimizu, S.1
Matsuoka, Y.2
Shinohara, Y.3
Yoneda, Y.4
Tsujimoto, Y.5
-
27
-
-
0027168907
-
Identification of the major phosphorylation sites of the Raf-1 kinase
-
Morrison DK, Heidecker G, Rapp UR, Copeland TD: Identification of the major phosphorylation sites of the Raf-1 kinase. J Biol Chem. 1993, 268:17309-16
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17309-17316
-
-
Morrison, D.K.1
Heidecker, G.2
Rapp, U.R.3
Copeland, T.D.4
-
28
-
-
0026872512
-
Studies on human porin. VII. The channel properties of the human B-lymphocyte membrane-derived "Porin 31HL" are similar to those of mitochondrial porins
-
Benz R, Maier E, Thinnes FP, Gotz H, Hilschmann N: Studies on human porin. VII. The channel properties of the human B-lymphocyte membrane-derived "Porin 31HL" are similar to those of mitochondrial porins. Biol Chem Hoppe Seyler. 1992, 373:295-303
-
(1992)
Biol. Chem. Hoppe Seyler
, vol.373
, pp. 295-303
-
-
Benz, R.1
Maier, E.2
Thinnes, F.P.3
Gotz, H.4
Hilschmann, N.5
-
29
-
-
0031857554
-
Conformational changes in the mitochondrial channel protein, VDAC, and their functional implications
-
Mannella CA: Conformational changes in the mitochondrial channel protein, VDAC, and their functional implications. J Struct Biol. 1998, 121:207-18
-
(1998)
J. Struct. Biol.
, vol.121
, pp. 207-218
-
-
Mannella, C.A.1
-
30
-
-
0035380462
-
Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane
-
Vander Heiden MG, Li XX, Gottleib E, Hill RB, Thompson CB, Colombini M: Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane. J Biol Chem. 2001, 276:19414-9
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19414-19419
-
-
Vander Heiden, M.G.1
Li, X.X.2
Gottleib, E.3
Hill, R.B.4
Thompson, C.B.5
Colombini, M.6
-
31
-
-
0033942156
-
Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis
-
Gottlieb E, Vander Heiden MG, Thompson CB: Bcl-x(L) prevents the initial decrease in mitochondrial membrane potential and subsequent reactive oxygen species production during tumor necrosis factor alpha-induced apoptosis. Mol Cell Biol. 2000, 20:5680-9
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 5680-5689
-
-
Gottlieb, E.1
Vander Heiden, M.G.2
Thompson, C.B.3
-
32
-
-
0034712944
-
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival
-
Vander Heiden MG, Chandel NS, Li XX, Schumacker PT, Colombini M, Thompson CB: Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival. Proc Natl Acad Sci U S A. 2000, 97:4666-71
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 4666-4671
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Li, X.X.3
Schumacker, P.T.4
Colombini, M.5
Thompson, C.B.6
-
33
-
-
0024347661
-
Interaction of non-classical detergents with the mitochondrial porin. A new purification procedure and characterization of the pore-forming unit
-
De Pinto V, Benz R, Palmieri F: Interaction of non-classical detergents with the mitochondrial porin. A new purification procedure and characterization of the pore-forming unit. Eur J Biochem. 1989, 183:179-87
-
(1989)
Eur. J. Biochem.
, vol.183
, pp. 179-187
-
-
De Pinto, V.1
Benz, R.2
Palmieri, F.3
|