Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer

British Journal of Cancer

Volumn 93, Issue 12, 2005, Pages 1372-1381

  Lin, H J ^a   Hsieh, F C ^b   Song, H ^c   Lin, J ^a,b,d  

^a OHIO STATE UNIVERSITY   (United States)

^b THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

AKT; Breast cancer; mTOR; p70S6K; PDK 1; Phosphorylation

Indexed keywords

3 PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FOCAL ADHESION KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN ANTIBODY; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN SHC; S6 KINASE; STAT3 PROTEIN; TELOMERASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; BREAST; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL CULTURE; CANCER INVASION; CANCER TISSUE; CELL IMMORTALIZATION; CELL STRAIN MCF 7; DOWNSTREAM PROCESSING; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ASSAY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; METASTASIS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TISSUE MICROARRAY; WESTERN BLOTTING;

BREAST NEOPLASMS; CARCINOMA; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; HUMANS; NEOPLASM INVASIVENESS; PHENOTYPE; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 28644435769     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602862     Document Type: Article

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