메뉴 건너뛰기




Volumn 97, Issue 6, 2003, Pages 1573-1581

Levels of hypoxia-inducible factor-1α independently predict prognosis in patients with lymph node negative breast carcinoma

Author keywords

Breast carcinoma; Estrogen receptor; HER 2 neu; Hypoxia inducible factor 1 ; Mitotic activity index; Progesterone receptor; Prognosis

Indexed keywords

EOSIN; ESTROGEN RECEPTOR; HEMATOXYLIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KI 67 ANTIGEN; PROGESTERONE RECEPTOR; VASCULOTROPIN;

EID: 0037443587     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.11246     Document Type: Article
Times cited : (473)

References (39)
  • 1
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
    • Hockel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst. 2001;93:266-276.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 266-276
    • Hockel, M.1    Vaupel, P.2
  • 2
    • 0034006016 scopus 로고    scopus 로고
    • HIF-1: Mediator of physiological and pathophysiological responses to hypoxia
    • Semenza GL. HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol. 2000;88: 1474-1480.
    • (2000) J Appl Physiol , vol.88 , pp. 1474-1480
    • Semenza, G.L.1
  • 3
    • 0034021690 scopus 로고    scopus 로고
    • Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
    • Semenza GL. Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit Rev Biochem Mol Biol. 2000;35:71-103.
    • (2000) Crit Rev Biochem Mol Biol , vol.35 , pp. 71-103
    • Semenza, G.L.1
  • 4
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor-1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular 02 tension
    • Wang GL, Jiang BH, Rue EA, Semenza GL. Hypoxia-inducible factor-1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular 02 tension. Proc Natl Acad Sci USA. 1995;92:5510-5514.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 6
    • 0029753008 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit
    • Huang LE, Arany Z, Livingston DM, Bunn HF. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J Biol Chem. 1996;271:32253-32259.
    • (1996) J Biol Chem , vol.271 , pp. 32253-32259
    • Huang, L.E.1    Arany, Z.2    Livingston, D.M.3    Bunn, H.F.4
  • 8
    • 0033954247 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha
    • Ravi R, Mookerjee B, Bhujwalla ZM, et al. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes Dev. 2000;14:34-44.
    • (2000) Genes Dev , vol.14 , pp. 34-44
    • Ravi, R.1    Mookerjee, B.2    Bhujwalla, Z.M.3
  • 9
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 1999;399:271-275.
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3
  • 10
    • 0033233243 scopus 로고    scopus 로고
    • Regulation of mammalian 02 homeostasis by hypoxia-inducible factor 1
    • Semenza GL. Regulation of mammalian 02 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol. 1999;15: 551-578.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 11
    • 0032053169 scopus 로고    scopus 로고
    • Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression
    • Ratcliffe PJ, O'Rourke JF, Maxwell PH, Pugh CW. Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J Exp Biol. 1998;201:1153-1162.
    • (1998) J Exp Biol , vol.201 , pp. 1153-1162
    • Ratcliffe, P.J.1    O'Rourke, J.F.2    Maxwell, P.H.3    Pugh, C.W.4
  • 12
    • 0030816109 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
    • Maxwell PH, Dachs GU, Gleadle JM, et al. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc Natl Acad Sci USA. 1997;94:8104-8109.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8104-8109
    • Maxwell, P.H.1    Dachs, G.U.2    Gleadle, J.M.3
  • 13
    • 0027043136 scopus 로고
    • Tumor angiogenesis: A new significant and independent prognostic indicator in early-stage breast carcinoma
    • Weidner N, Folkman J, Pozza F, et al. Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst. 1992;84: 1875-1887.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 1875-1887
    • Weidner, N.1    Folkman, J.2    Pozza, F.3
  • 14
    • 0034076192 scopus 로고    scopus 로고
    • Hot spot microvessel density and the mitotic activity index are strong additional prognostic indicators in invasive breast cancer
    • De Jong JS, van Diest PJ, Baak JP. Hot spot microvessel density and the mitotic activity index are strong additional prognostic indicators in invasive breast cancer. Histopathology. 2000;36:306-312.
    • (2000) Histopathology , vol.36 , pp. 306-312
    • De Jong, J.S.1    Van Diest, P.J.2    Baak, J.P.3
  • 15
    • 0030982113 scopus 로고    scopus 로고
    • Antiangiogenesis for cancer therapy
    • Harris AL. Antiangiogenesis for cancer therapy. Lancet. 1997;349(Suppl 2):SII13-SII15.
    • (1997) Lancet , vol.349 , Issue.SUPPL. 2
    • Harris, A.L.1
  • 16
    • 0031671095 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma
    • Linderholm B, Tavelin B, Grankvist K, Henriksson R. Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma. J Clin Oncol. 1998;16:3121- 3128.
    • (1998) J Clin Oncol , vol.16 , pp. 3121-3128
    • Linderholm, B.1    Tavelin, B.2    Grankvist, K.3    Henriksson, R.4
  • 17
  • 18
    • 0033986761 scopus 로고    scopus 로고
    • Causes and consequences of tumour acidity and implications for treatment
    • Stubbs M, McSheehy PM, Griffiths JR, Bashford CL. Causes and consequences of tumour acidity and implications for treatment. Mol Med Today. 2000;6:15-19.
    • (2000) Mol Med Today , vol.6 , pp. 15-19
    • Stubbs, M.1    McSheehy, P.M.2    Griffiths, J.R.3    Bashford, C.L.4
  • 19
    • 0035925072 scopus 로고    scopus 로고
    • Levels of hypoxiainducible factor-1alpha during breast carcinogenesis
    • Bos R, Zhong H, Hanrahan CF, et al. Levels of hypoxiainducible factor-1alpha during breast carcinogenesis. J Natl Cancer Inst. 2001;93:309-314.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 309-314
    • Bos, R.1    Zhong, H.2    Hanrahan, C.F.3
  • 20
    • 0035881075 scopus 로고    scopus 로고
    • Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma
    • Chia SK, Wykoff CC, Watson PH, et al. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma. J Clin Oncol. 2001;19:3660-3668.
    • (2001) J Clin Oncol , vol.19 , pp. 3660-3668
    • Chia, S.K.1    Wykoff, C.C.2    Watson, P.H.3
  • 21
    • 0035012605 scopus 로고    scopus 로고
    • Her2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (hif-1alpha) synthesis: Novel mechanism for hif-1-mediated vascular endothelial growth factor expression
    • Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL. Her2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (hif-1alpha) synthesis: novel mechanism for hif-1-mediated vascular endothelial growth factor expression. Mol Cell Biol. 2001;21:3995-4004.
    • (2001) Mol Cell Biol , vol.21 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 22
    • 0034282518 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in earlystage invasive cervical cancer
    • Birner P, Schindl M, Obermair A, Plank C, Breitenecker G, Oberhuber G. Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in earlystage invasive cervical cancer. Cancer Res. 2000;60:4693-4696.
    • (2000) Cancer Res , vol.60 , pp. 4693-4696
    • Birner, P.1    Schindl, M.2    Obermair, A.3    Plank, C.4    Breitenecker, G.5    Oberhuber, G.6
  • 23
    • 0035300410 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha: A novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer
    • Aebersold DM, Burri P, Beer KT, et al. Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer. Cancer Res. 2001;61:2911-2916.
    • (2001) Cancer Res , vol.61 , pp. 2911-2916
    • Aebersold, D.M.1    Burri, P.2    Beer, K.T.3
  • 24
    • 0035395098 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: Its impact on prognosis and on neoangiogenesis
    • Birner P, Gatterbauer B, Oberhuber G, et al. Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis. Cancer. 2001; 92:165-171.
    • (2001) Cancer , vol.92 , pp. 165-171
    • Birner, P.1    Gatterbauer, B.2    Oberhuber, G.3
  • 25
    • 0035860147 scopus 로고    scopus 로고
    • Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival
    • Giatromanolaki A, Koukourakis MI, Sivridis E, et al. Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival. Br J Cancer. 2001;85:881-890.
    • (2001) Br J Cancer , vol.85 , pp. 881-890
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3
  • 26
    • 0342433777 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer
    • Volm M, Koomagi R. Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer. Anticancer Res. 2000;20:1527-1533.
    • (2000) Anticancer Res , vol.20 , pp. 1527-1533
    • Volm, M.1    Koomagi, R.2
  • 27
    • 0036569941 scopus 로고    scopus 로고
    • Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: Relationship to tumor biology and treatment outcome in surgically resected patients
    • Beasley NJ, Leek R, Alam M, et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res. 2002;62:2493-2497.
    • (2002) Cancer Res , vol.62 , pp. 2493-2497
    • Beasley, N.J.1    Leek, R.2    Alam, M.3
  • 28
    • 0037169870 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 alpha (HIF-1 alpha) gene expression in human ovarian carcinoma
    • Nakayama K, Kanzaki A, Hata K, et al. Hypoxia-inducible factor 1 alpha (HIF-1 alpha) gene expression in human ovarian carcinoma. Cancer Lett. 2002;176:215-223.
    • (2002) Cancer Lett , vol.176 , pp. 215-223
    • Nakayama, K.1    Kanzaki, A.2    Hata, K.3
  • 29
    • 0025916196 scopus 로고
    • Prognosis and breast cancer. Recognition of lethal and favorable prognostic types
    • Page DL. Prognosis and breast cancer. Recognition of lethal and favorable prognostic types. Am J Surg Pathol. 1991;15: 334-349.
    • (1991) Am J Surg Pathol , vol.15 , pp. 334-349
    • Page, D.L.1
  • 30
    • 0029122836 scopus 로고
    • Comparison of the prognostic value of four methods to assess mitotic activity in 186 invasive breast cancer patients: Classical and random mitotic activity assessments with correction for volume percentage of epithelium
    • Jannink I, van Diest PI, Baak JP. Comparison of the prognostic value of four methods to assess mitotic activity in 186 invasive breast cancer patients: classical and random mitotic activity assessments with correction for volume percentage of epithelium. Hum Pathol. 1995;26:1086-1092.
    • (1995) Hum Pathol , vol.26 , pp. 1086-1092
    • Jannink, I.1    Van Diest, P.I.2    Baak, J.P.3
  • 31
    • 0020315439 scopus 로고
    • Histological typing of breast tumors
    • World Health Organization. Histological typing of breast tumors. Tumori. 1982;68:181-198.
    • (1982) Tumori , vol.68 , pp. 181-198
  • 32
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer; experience from a large study with long-term follow-up
    • Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer; experience from a large study with long-term follow-up. Histopathology. 1991;19:403-410.
    • (1991) Histopathology , vol.19 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 34
    • 0037080449 scopus 로고    scopus 로고
    • Biologic correlates of (18)fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography
    • Bos R, van der Hoeven JJM, van der Wall E, et al. Biologic correlates of (18)fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography. J Clin Oncol. 2002;20:379-387.
    • (2002) J Clin Oncol , vol.20 , pp. 379-387
    • Bos, R.1    Van der Hoeven, J.J.M.2    Van der Wall, E.3
  • 35
    • 0033571682 scopus 로고    scopus 로고
    • Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
    • Zhong H, De Marzo AM, Laughner E, et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res. 1999;59:5830-5835.
    • (1999) Cancer Res , vol.59 , pp. 5830-5835
    • Zhong, H.1    De Marzo, A.M.2    Laughner, E.3
  • 36
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature. 2000;407:249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 37
    • 0026569544 scopus 로고
    • Quality control in immunocytochemistry: Experiences with the oestrogen receptor assay
    • Bosman FT, de Goeij AF, Rousch M. Quality control in immunocytochemistry: experiences with the oestrogen receptor assay. J Clin Pathol. 1992;45:120-124.
    • (1992) J Clin Pathol , vol.45 , pp. 120-124
    • Bosman, F.T.1    De Goeij, A.F.2    Rousch, M.3
  • 38
    • 0026772950 scopus 로고
    • Reproducibility of mitosis counting in 2469 breast cancer specimens: Results from the Multicenter Morphometric Mammary Carcinoma Project
    • van Diest PJ, Baak JP, Matze-Cok P, et al. Reproducibility of mitosis counting in 2469 breast cancer specimens: results from the Multicenter Morphometric Mammary Carcinoma Project. Hum Pathol. 1992;23:603-607.
    • (1992) Hum Pathol , vol.23 , pp. 603-607
    • Van Diest, P.J.1    Baak, J.P.2    Matze-Cok, P.3
  • 39
    • 0034000338 scopus 로고    scopus 로고
    • Prognostic value of vascular endothelial growth factor in breast cancer
    • Gasparini G. Prognostic value of vascular endothelial growth factor in breast cancer. Oncologist. 2000;5(Suppl 1):37-44.
    • (2000) Oncologist , vol.5 , Issue.SUPPL. 1 , pp. 37-44
    • Gasparini, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.