Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH

FEBS Letters

Volumn 577, Issue 3, 2004, Pages 439-445

  Švastová, Eliška ^a   Hulíková, Alžbeta ^a   Rafajová, Monika ^a   Zat'Ovičová, Miriam ^a   Gibadulinová, Adriana ^a   Casini, Angela ^b   Cecchi, Alessandro ^b   Scozzafava, Andrea ^b   Supuran, Claudiu T ^b   Pastorek, Jaromír ^a   Pastoreková, Silvia ^a  

^a INSTITUTE OF VIROLOGY   (Slovakia)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

CA, deletion mutant of CA IX lacking the catalytic domain; PG, deletion mutant of CA IX lacking the proteoglycan like domain; AE, anion exchanger; CA, carbonic anhydrase; CAI, carbonic anhydrase inhibitor; HIF, hypoxia inducible factor

Indexed keywords

4 (2 AMINOETHYL)BENZENESULFONAMIDE; 4 (2,4,6 TRIMETHYLPYRIDINIUM N METHYLCARBOXAMIDO)BENZENESULFONAMIDE PERCHLORATE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE IX; FLUORESCEIN THIOREIDO HOMOSULFANILAMIDE; SULFONAMIDE; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVE SITE; FEMALE; HUMAN; HUMAN CELL; HYPOXIA; HYPOXIC CELL; NONHUMAN; PRIORITY JOURNAL;

ACIDOSIS; ANIMALS; ANTIGENS, NEOPLASM; BINDING SITES; BIOTINYLATION; CARBONIC ANHYDRASES; CELL HYPOXIA; CELL LINE; CLONING, MOLECULAR; CULTURE MEDIA; DOGS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; ISOENZYMES; MOLECULAR STRUCTURE; PRECIPITIN TESTS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; SULFONAMIDES; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 8844249356     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.10.043     Document Type: Article

References (32)

1. Stubbs M., McSheehy P.M.J., Griffiths J.R., Bashford C.L. Mol. Med. Today. 6:2000;15-19
2. Fukumura D., Xu L., Chen Y., Gohongi T., Seed B., Jain R.K. Cancer Res. 61:2001;6020-6024
3. Kato Y., Nakayama Y., Umeda M., Miyazaki K. J. Biol. Chem. 267:1992;11424-11430
4. Martinez-Zaguilan R., Seftor E.A., Seftor R.E., Chu Y.W., Gillies R.J., Hendrix M.J. Clin. Exp. Metastasis. 14:1992;176-186
5. Fischer B., Muller B., Fischer K.G., Baur N., Kreutz W. Clin. Immunol. 96:2000;252-263
6. Gerweck L.E. Semin. Radiat. Oncol. 8:1998;176-182
7. Newell K., Franchi A., Pouyssegur J., Tannock I. Proc. Natl. Acad. Sci. USA. 90:1993;1127-1131
8. Yamagata M., Hasuda K., Stamato T., Tannock I.F. Br. J. Cancer. 77:1998;1726-1731
9. Helmlinger G., Sckell A., Dellian M., Forbes N.S., Jain R.K. Clin. Cancer Res. 8:2002;1284-1291
10. Supuran C.T., Scozzafava A., Casini A. Med. Res. Rev. 23:2003;146-189
11. Pastorek J., Pastorekova S., Callebaut I., Mornon J.P., Zelnik V., Opavsky R., Zatovicova M., Liao S., Portetelle D., Stanbridge E.J., Zavada J., Burny A., Kettmann R. Oncogene. 9:1994;2788-2888
12. Opavsky R., Pastorekova S., Zelnik V., Gibadulinova A., Stanbridge E.J., Zavada J., Kettmann R., Pastorek J. Genomics. 33:1996;480-487
13. Wingo T., Tu C., Laipis P.J., Silverman D.N. Biochem. Biophys. Res. Commun. 288:2001;666-669
14. Pastorekova S., Pastorek J. Supuran C.T., Scozzafava A., Conway J. Carbonic Anhydrase, its Inhibitors and Activators. 2004;253-272 CRC Press, Boca Raton, FL, USA
15. Wykoff C., Beasley N., Watson P., Turner L., Pastorek J., Wilson G., Turley H., Maxwell P., Pugh C., Ratcliffe P., Harris A. Cancer Res. 60:2000;7075-7083
16. Potter C.P.S., Harris A.L. Br. J. Cancer. 89:2003;2-7
17. Svastova E., Zilka N., Zatovicova M., Gibadulinova A., Ciampor F., Pastorek J., Pastorekova S. Exp. Cell Res. 290:2003;332-345
18. Scozzafava A., Briganti F., Ilies M., Supuran C.T. J. Med. Chem. 43:2000;292-300
19. Supuran C.T., Scozzafava A., Jurca B.C., Ilies M.A. Eur. J. Med. Chem. 33:1998;83-93
20. Zatovicova M., Tarabkova K., Svastova E., Gibadulinova A., Mucha A., Jakubickova L., Biesova Z., Rafajova M., Gut M.O., Parkkila S., Parkkila A.K., Waheed A., Sly W.S., Horak I., Pastorek J., Pastorekova S. J. Immunol. Methods. 282:2003;117-134
21. Pastorekova S., Závadova Z., Kostal M., Babusikova O., Zavada J. Virology. 187:1992;620-626
22. Vullo D., Franchi M., Gallori E., Pastorek J., Scozzafava A., Pastorekova S., Supuran C.T. Bioorg. Med. Chem. Lett. 13:2003;1005-1009
23. Pastorekova S., Casini A., Scozzafava A., Vullo D., Pastorek J., Supuran C.T. Bioorg. Med. Chem. Lett. 14:2004;869-873
24. Zavada J., Zavadova Z., Pastorek J., Biesova Z., Jezek J., Velek J. Br. J. Cancer. 82:2000;1808-1813
25. Semenza G.L. Nat. Rev. Cancer. 3:2003;721-732
26. Teicher B.A., Liu S.D., Liu L.T., Holden S.A., Herman T.S. Anticancer Res. 13:1993;1549-1556
27. Casini A., Scozzafava A., Mastrolorenzo A., Supuran C.T. Cur. Cancer Drug Targets. 2:2002;55-75
28. Sterling D., Reithmeier R.A.F., Casey J.R. J. Biol. Chem. 276:2001;47886-47894
29. Sterling D., Alvarez B.V., Casey J.R. J. Biol. Chem. 277:2002;25239-25246
30. Ivanov S.V., Kuzmin I., Wei M.H., Pack S., Geil L., Johnson B.E., Stanbridge E.J., Lerman M.I. Proc. Natl. Acad. Sci. USA. 95:1998;12596-12601
31. Karumanchi S.A., Jiang L., Knebelmann B., Stuart-Tilley A.K., Alper S.L., Sukhatme V.P. Physiol. Genom. 5:2001;119-128
32. Mekhail K., Gunaratnam L., Boncalzi M.E., Lee S. Nat. Cell Biol. 6:2004;642-647