-
1
-
-
0018140371
-
Role of cell shape in growth control
-
Folkman J, Moscona A: Role of cell shape in growth control. Nature 1978, 273:345-349.
-
(1978)
Nature
, vol.273
, pp. 345-349
-
-
Folkman, J.1
Moscona, A.2
-
2
-
-
0028057613
-
Disruption of epithelial cell-matrix interactions induces apoptosis
-
Frisch SM, Francis H: Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 1994, 124:619-626.
-
(1994)
J Cell Biol
, vol.124
, pp. 619-626
-
-
Frisch, S.M.1
Francis, H.2
-
4
-
-
0028335948
-
Anchorage independence, integrins and apoptosis
-
Ruoslahti E, Reed J: Anchorage independence, integrins and apoptosis. Cell 1994, 77:477-478.
-
(1994)
Cell
, vol.77
, pp. 477-478
-
-
Ruoslahti, E.1
Reed, J.2
-
6
-
-
0028314140
-
Apoptosis in human skin development: Morphogenesis, periderm and stem cells
-
Polakowska R, Piacentini M, Bartlett R, Goldsmith L, Haake A: Apoptosis in human skin development: morphogenesis, periderm and stem cells. Dev Dyn 1994, 3:176-188.
-
(1994)
Dev Dyn
, vol.3
, pp. 176-188
-
-
Polakowska, R.1
Piacentini, M.2
Bartlett, R.3
Goldsmith, L.4
Haake, A.5
-
7
-
-
0028589378
-
Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis
-
Hall P, Coates P, Ansari B, Hopwood D: Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci 1994, 107:3569-3577.
-
(1994)
J Cell Sci
, vol.107
, pp. 3569-3577
-
-
Hall, P.1
Coates, P.2
Ansari, B.3
Hopwood, D.4
-
8
-
-
0028927484
-
Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix
-
Boudreau N, Sympson CJ, Werb Z, Bissell MJ: Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science 1995, 267:891-893.
-
(1995)
Science
, vol.267
, pp. 891-893
-
-
Boudreau, N.1
Sympson, C.J.2
Werb, Z.3
Bissell, M.J.4
-
9
-
-
0028818755
-
Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo
-
Coucouvanis E, Martin G: Signals for death and survival: a two-step mechanism for cavitation in the vertebrate embryo. Cell 1995, 83:279-287.
-
(1995)
Cell
, vol.83
, pp. 279-287
-
-
Coucouvanis, E.1
Martin, G.2
-
10
-
-
0029794008
-
Merosin and laminin in myogenesis; specific requirement for merosin in myotube stability and survival
-
Vachon P, Loechel F, Xu H, Wewer U, Engvall E: Merosin and laminin in myogenesis; specific requirement for merosin in myotube stability and survival. J Cell Biol 1996, 134:1483-1487.
-
(1996)
J Cell Biol
, vol.134
, pp. 1483-1487
-
-
Vachon, P.1
Loechel, F.2
Xu, H.3
Wewer, U.4
Engvall, E.5
-
11
-
-
0028670298
-
Integrin αvβ3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen
-
Montgomery A, Reisfeld R, Cheresh D: Integrin αvβ3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Natl Acad Sci USA 1994, 91:8856-8860.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8856-8860
-
-
Montgomery, A.1
Reisfeld, R.2
Cheresh, D.3
-
12
-
-
0030300180
-
Inhibition of pp125FAK in cultured fibroblasts results in apoptosis
-
Hungerford J, Compton J, Matter J, Hoffstrom B, Otey C: Inhibition of pp125FAK in cultured fibroblasts results in apoptosis. J Cell Biol 1996, 135:1383-1390.
-
(1996)
J Cell Biol
, vol.135
, pp. 1383-1390
-
-
Hungerford, J.1
Compton, J.2
Matter, J.3
Hoffstrom, B.4
Otey, C.5
-
13
-
-
0029051340
-
Cellular growth and survival are mediated by β1 integrins in normal human breast epithelium but not in breast carcinoma
-
Howlett A, Bailey N, Damsky C, Peterson O, Bissell M: Cellular growth and survival are mediated by β1 integrins in normal human breast epithelium but not in breast carcinoma. J Cell Sci 1995, 108:1945-1957.
-
(1995)
J Cell Sci
, vol.108
, pp. 1945-1957
-
-
Howlett, A.1
Bailey, N.2
Damsky, C.3
Peterson, O.4
Bissell, M.5
-
14
-
-
0028983407
-
The α5β1 integrin supports survival of cells on fibronectin and upregulates bcl-2 expression
-
Zhang Z, Vuori K, Reed J, Ruoslahti E: The α5β1 integrin supports survival of cells on fibronectin and upregulates bcl-2 expression. Proc Natl Acad Sci USA 1995, 92:6161-6165.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6161-6165
-
-
Zhang, Z.1
Vuori, K.2
Reed, J.3
Ruoslahti, E.4
-
15
-
-
0030584077
-
The adaptor protein Shc couples a class of integrins to the control of cell cycle progression
-
Provides evidence that certain integrins activate mitogen-activated protein kinases through Shc
-
Wary K, Mainiero F, Isakoff S, Marcantonio E, Giancotti F: The adaptor protein Shc couples a class of integrins to the control of cell cycle progression. Cell 1996, 87:733-743. Provides evidence that certain integrins activate mitogen-activated protein kinases through Shc.
-
(1996)
Cell
, vol.87
, pp. 733-743
-
-
Wary, K.1
Mainiero, F.2
Isakoff, S.3
Marcantonio, E.4
Giancotti, F.5
-
16
-
-
0029984473
-
Expression of the integrin α5 subunit in HT29 colon carcinoma cells suppresses apoptosis triggered by serum deprivation
-
O'Brien V, Frisch S, Juliano R: Expression of the integrin α5 subunit in HT29 colon carcinoma cells suppresses apoptosis triggered by serum deprivation. Exp Cell Res 1996, 224:208-213.
-
(1996)
Exp Cell Res
, vol.224
, pp. 208-213
-
-
O'Brien, V.1
Frisch, S.2
Juliano, R.3
-
17
-
-
0028670833
-
Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
-
Brooks P, Montgomery A, Rosenfeld M, Reisfeld R, Hu T, Klier G, Cheresh D: Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994, 79:1157-1164.
-
(1994)
Cell
, vol.79
, pp. 1157-1164
-
-
Brooks, P.1
Montgomery, A.2
Rosenfeld, M.3
Reisfeld, R.4
Hu, T.5
Klier, G.6
Cheresh, D.7
-
18
-
-
0029092648
-
Activation of the p21 pathway of growth arrest and apoptosis by the 14 integrin cytoplasmic domain
-
Clarke A, Lotz M, Chao C, Mercurio A: Activation of the p21 pathway of growth arrest and apoptosis by the [14 integrin cytoplasmic domain. J Biol Chem 1995, 270:22673-22676.
-
(1995)
J Biol Chem
, vol.270
, pp. 22673-22676
-
-
Clarke, A.1
Lotz, M.2
Chao, C.3
Mercurio, A.4
-
19
-
-
0028641601
-
Association of insulin receptor substrate-1 with integrins
-
Vuori K, Ruoslahti E: Association of insulin receptor substrate-1 with integrins. Science 1994, 266:1576-1578.
-
(1994)
Science
, vol.266
, pp. 1576-1578
-
-
Vuori, K.1
Ruoslahti, E.2
-
20
-
-
0030814976
-
αvβ3 integrin associates with activated insulin and PDGFβ receptors and potentiates the biological activity of PDGF
-
in press
-
Schneller M, Vuori K, Ruoslahti E: αvβ3 integrin associates with activated insulin and PDGFβ receptors and potentiates the biological activity of PDGF. EMBO J 1997, in press.
-
(1997)
EMBO J
-
-
Schneller, M.1
Vuori, K.2
Ruoslahti, E.3
-
21
-
-
0027682591
-
Adhesion molecules in cancer: The role of integrins
-
Juliano RL, Varner JA: Adhesion molecules in cancer: the role of integrins. Curr Opin Cell Biol 1993, 5:812-818.
-
(1993)
Curr Opin Cell Biol
, vol.5
, pp. 812-818
-
-
Juliano, R.L.1
Varner, J.A.2
-
22
-
-
0028072225
-
Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells
-
Re F, Zanetti M, Sironi N, Polentarutti L, Lanfrancone E, Dejana E, Colotta F: Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells. J Cell Biol 1994, 127:537-546.
-
(1994)
J Cell Biol
, vol.127
, pp. 537-546
-
-
Re, F.1
Zanetti, M.2
Sironi, N.3
Polentarutti, L.4
Lanfrancone, E.5
Dejana, E.6
Colotta, F.7
-
23
-
-
0029775681
-
RGD and other recognition sequences for integrins
-
Ruoslahti E: RGD and other recognition sequences for integrins. Annu Rev Cell Dev Biol 1996, 12:697-715.
-
(1996)
Annu Rev Cell Dev Biol
, vol.12
, pp. 697-715
-
-
Ruoslahti, E.1
-
24
-
-
0028306464
-
LPA stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin and p130. Signaling pathways and cross-talk with PDGF
-
SeufferleinT, Rozengurt E: LPA stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin and p130. Signaling pathways and cross-talk with PDGF. J Biol Chem 1994, 269:9345-9351.
-
(1994)
J Biol Chem
, vol.269
, pp. 9345-9351
-
-
Seufferlein, T.1
Rozengurt, E.2
-
25
-
-
0030953763
-
Geometric control of cell life and death
-
The authors of this paper devised a way of altering cell shape while keeping constant the surface area onto which the cells were attached. The results showed that cell shape is an important regulator of apoptosis
-
Chen CS, Mrkisch M, Huang S, Whitesides GM, Ingber D: Geometric control of cell life and death. Science 1997, 276:1425-1428. The authors of this paper devised a way of altering cell shape while keeping constant the surface area onto which the cells were attached. The results showed that cell shape is an important regulator of apoptosis.
-
(1997)
Science
, vol.276
, pp. 1425-1428
-
-
Chen, C.S.1
Mrkisch, M.2
Huang, S.3
Whitesides, G.M.4
Ingber, D.5
-
26
-
-
0031035693
-
Bcl-2 is the guardian of microtubule integrity
-
Demonstrates the potency with which microtubular pertubations induce apoptosis
-
Haldar S, Basu A, Croce C: Bcl-2 is the guardian of microtubule integrity. Cancer Res 1997, 57:229-233. Demonstrates the potency with which microtubular pertubations induce apoptosis.
-
(1997)
Cancer Res
, vol.57
, pp. 229-233
-
-
Haldar, S.1
Basu, A.2
Croce, C.3
-
27
-
-
0026876908
-
Cell adhesion in invasion and metastasis
-
Behrens J, Frixen U, Schipper J, Weidner M, Birchmeier W: Cell adhesion in invasion and metastasis. Semin Cell Biol 1992, 3:169-178.
-
(1992)
Semin Cell Biol
, vol.3
, pp. 169-178
-
-
Behrens, J.1
Frixen, U.2
Schipper, J.3
Weidner, M.4
Birchmeier, W.5
-
28
-
-
0342981801
-
Wnt signaling goes nuclear
-
Kuhl M, Wedlich D: Wnt signaling goes nuclear. Bioessays 1997, 19:101-104.
-
(1997)
Bioessays
, vol.19
, pp. 101-104
-
-
Kuhl, M.1
Wedlich, D.2
-
29
-
-
0028258533
-
Apoptosis induced by inhibition of intercellular contact
-
Bates R, Buret A, van Helden D, Horton M, Burns G: Apoptosis induced by inhibition of intercellular contact J Cell Biol 1994, 125:403-415.
-
(1994)
J Cell Biol
, vol.125
, pp. 403-415
-
-
Bates, R.1
Buret, A.2
Van Helden, D.3
Horton, M.4
Burns, G.5
-
30
-
-
0028609382
-
Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
-
Schlaepfer DD, Hanks SK, Hunter T, Van der Geer P: Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 1994, 372:786-791.
-
(1994)
Nature
, vol.372
, pp. 786-791
-
-
Schlaepfer, D.D.1
Hanks, S.K.2
Hunter, T.3
Van Der Geer, P.4
-
31
-
-
0027967292
-
A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to PP125FAK
-
Chan P-Y, Kanner SB, Whitney G, Aruffo AA: A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to PP125FAK. J Biol Chem 1994, 269:20567-20574.
-
(1994)
J Biol Chem
, vol.269
, pp. 20567-20574
-
-
Chan, P.-Y.1
Kanner, S.B.2
Whitney, G.3
Aruffo, A.A.4
-
32
-
-
0030458602
-
A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA
-
Frisch S, Vuori K, Kelaita D, Sicks S: A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA. J Cell Biol 1996, 135:1377-1382.
-
(1996)
J Cell Biol
, vol.135
, pp. 1377-1382
-
-
Frisch, S.1
Vuori, K.2
Kelaita, D.3
Sicks, S.4
-
33
-
-
0029739950
-
Control of adhesion-dependent cell survival by focal adhesion kinase
-
This paper demonstrates that focal adhesion kinase may control anoikis
-
Frisch S, Vuori K, Ruoslahti E, Chan-Hui PY: Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 1996, 134:793-799. This paper demonstrates that focal adhesion kinase may control anoikis.
-
(1996)
J Cell Biol
, vol.134
, pp. 793-799
-
-
Frisch, S.1
Vuori, K.2
Ruoslahti, E.3
Chan-Hui, P.Y.4
-
34
-
-
0029848157
-
Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells
-
Xu L-H, Owens LV, Sturge GC, Yang X, Liu ET, Craven RJ, Cance WG: Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells. Cell Growth Differ 1996, 7:413-418.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 413-418
-
-
Xu, L.-H.1
Owens, L.V.2
Sturge, G.C.3
Yang, X.4
Liu, E.T.5
Craven, R.J.6
Cance, W.G.7
-
36
-
-
0030904561
-
The PI 3-kinase/AKT signaling pathway delivers an anti-apoptotic signal
-
Kennedy S, Wagner A, Conzen S, Jordan J, Bellacosa A, Tsichlis P, Hay N: The PI 3-kinase/AKT signaling pathway delivers an anti-apoptotic signal. Genes Dev 1997, 11:703-713.
-
(1997)
Genes Dev
, vol.11
, pp. 703-713
-
-
Kennedy, S.1
Wagner, A.2
Conzen, S.3
Jordan, J.4
Bellacosa, A.5
Tsichlis, P.6
Hay, N.7
-
37
-
-
0028972616
-
Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance
-
Reed J: Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance. Curr Opin Oncol 1995, 7:541-546.
-
(1995)
Curr Opin Oncol
, vol.7
, pp. 541-546
-
-
Reed, J.1
-
38
-
-
0030038229
-
Suppression of p53 activity and p21 expression by vascular cell integrin αvβ3 during angiogenesis
-
Stromblad S, Becker J, Yebra M, Brooks P, Cheresh D: Suppression of p53 activity and p21 expression by vascular cell integrin αvβ3 during angiogenesis. J Clin Invest 1996, 98:426-433.
-
(1996)
J Clin Invest
, vol.98
, pp. 426-433
-
-
Stromblad, S.1
Becker, J.2
Yebra, M.3
Brooks, P.4
Cheresh, D.5
-
39
-
-
0028823892
-
Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast
-
Waskiewicz A, Cooper J: Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast Curr Opin Cell Biol 1995, 7:798-805.
-
(1995)
Curr Opin Cell Biol
, vol.7
, pp. 798-805
-
-
Waskiewicz, A.1
Cooper, J.2
-
40
-
-
0030175485
-
Mitogen-activated protein kinase cascades and regulation of gene expression
-
Su B, Karin M: Mitogen-activated protein kinase cascades and regulation of gene expression. Curr Opin Immunol 1996, 8:402-411.
-
(1996)
Curr Opin Immunol
, vol.8
, pp. 402-411
-
-
Su, B.1
Karin, M.2
-
41
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME: Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995, 270:1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
42
-
-
0029912189
-
Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases
-
Demonstrates that bcl-2 functions upstream of caspases in apoptosis
-
Chinnaiyan AM, Orth K, O'Rourke K, Duan H, GPoirier GG, Dixit VM: Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases. J Biol Chem 1996, 271:4573-4576. Demonstrates that bcl-2 functions upstream of caspases in apoptosis.
-
(1996)
J Biol Chem
, vol.271
, pp. 4573-4576
-
-
Chinnaiyan, A.M.1
Orth, K.2
O'Rourke, K.3
Duan, H.4
GPoirier, G.G.5
Dixit, V.M.6
-
43
-
-
0030755579
-
Regulation of anoikis: MEKK-1 activation requires cleavage by caspases
-
This paper ties caspases to the activation of MEKK-1
-
Cardone M, Salvesen G, Widmann C, Johnson G, Frisch S: Regulation of anoikis: MEKK-1 activation requires cleavage by caspases. Cell 1997, 90:315-323. This paper ties caspases to the activation of MEKK-1.
-
(1997)
Cell
, vol.90
, pp. 315-323
-
-
Cardone, M.1
Salvesen, G.2
Widmann, C.3
Johnson, G.4
Frisch, S.5
-
44
-
-
0030998713
-
Induction of apoptosis by the transcription factor c-jun
-
Provides a possible mechanism for the induction of apoptosis by Jun amino-terminal kinases
-
Bossy-Wetzel E, Bakiri L, Yaniv M: Induction of apoptosis by the transcription factor c-jun. EMBO J 1997, 16:1695-1709. Provides a possible mechanism for the induction of apoptosis by Jun amino-terminal kinases.
-
(1997)
EMBO J
, vol.16
, pp. 1695-1709
-
-
Bossy-Wetzel, E.1
Bakiri, L.2
Yaniv, M.3
-
45
-
-
0031285250
-
Activation of the IκBα kinase complex by MEKK-1, a kinase of the JNK pathway
-
Lee F, Hagler J, Che Z, Maniatis T: Activation of the IκBα kinase complex by MEKK-1, a kinase of the JNK pathway. Cell 1997, 88:213-222.
-
(1997)
Cell
, vol.88
, pp. 213-222
-
-
Lee, F.1
Hagler, J.2
Che, Z.3
Maniatis, T.4
-
46
-
-
0030988914
-
Cell anchorage regulates apoptosis through the retinoblastoma tumor suppressor/E2F pathway
-
Demonstrates that bcl-2 suppresses the expression of cyclin dependent kinase inhibitors in suspended cells, thus maintaining the retinoblastoma protein (Rb) in a hyperphosphorylated, inactive state. This paper also shows a role for Rb-mediated growth arrest in anoikis
-
Day M, Foster R, Day K, Zhao X, Humphrey P, Swanson P, Postigo A, Zhang S, Dean D: Cell anchorage regulates apoptosis through the retinoblastoma tumor suppressor/E2F pathway. J Biol Chem 1997, 272:8125-8128. Demonstrates that bcl-2 suppresses the expression of cyclin dependent kinase inhibitors in suspended cells, thus maintaining the retinoblastoma protein (Rb) in a hyperphosphorylated, inactive state. This paper also shows a role for Rb-mediated growth arrest in anoikis.
-
(1997)
J Biol Chem
, vol.272
, pp. 8125-8128
-
-
Day, M.1
Foster, R.2
Day, K.3
Zhao, X.4
Humphrey, P.5
Swanson, P.6
Postigo, A.7
Zhang, S.8
Dean, D.9
-
47
-
-
0030026679
-
Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase
-
Hannigan GE, Leung-Hagesteijn CL, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, Bell JC, Dedhar S: Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase. Nature 1996, 379:91-96.
-
(1996)
Nature
, vol.379
, pp. 91-96
-
-
Hannigan, G.E.1
Leung-Hagesteijn, C.L.2
Fitz-Gibbon, L.3
Coppolino, M.G.4
Radeva, G.5
Filmus, J.6
Bell, J.C.7
Dedhar, S.8
-
48
-
-
0029770721
-
Activation of Pyk2 by stress signals and coupling with JNK signaling pathway
-
Tokiwa G, Dikic I, Lev S, Schlessinger J: Activation of Pyk2 by stress signals and coupling with JNK signaling pathway. Science 1996, 273:792-794.
-
(1996)
Science
, vol.273
, pp. 792-794
-
-
Tokiwa, G.1
Dikic, I.2
Lev, S.3
Schlessinger, J.4
-
49
-
-
0030222377
-
Rho: A connection between membrane receptor signalling and the cytoskeleton
-
Machesky LM, Hall A: Rho: a connection between membrane receptor signalling and the cytoskeleton. Trends Cell Biol 1996, 6:304-310.
-
(1996)
Trends Cell Biol
, vol.6
, pp. 304-310
-
-
Machesky, L.M.1
Hall, A.2
-
50
-
-
0030033193
-
Transducers of life and death: TNF receptor superfamily and associated proteins
-
Baker SJ, Reddy EP: Transducers of life and death: TNF receptor superfamily and associated proteins. Oncogens 1996, 12:1-9.
-
(1996)
Oncogens
, vol.12
, pp. 1-9
-
-
Baker, S.J.1
Reddy, E.P.2
|