An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: Implications for clonal selection during colorectal carcinogenesis

Oncogene

Volumn 18, Issue 21, 1999, Pages 3199-3204

  Williams, A C ^a   Collard, T J ^a   Paraskeva, C ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Apoptosis; Colon; p53; pH; pRb

Indexed keywords

PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN;

ACIDIFICATION; ADENOMA; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL CYCLE G1 PHASE; CELL PH; CELL SURVIVAL; COLORECTAL CANCER; CULTURE MEDIUM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACIDS; ADENOMA; APOPTOSIS; CELL SURVIVAL; COLORECTAL NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; HUMANS; RETINOBLASTOMA PROTEIN; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0033609365     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202660     Document Type: Article

References (32)

1. Baker SJ, Preisiner AC, Jessup JM, Paraskeva C, Markowitz S, Wilson JKV, Hamilton S and Vogelstein B. (1990). Cancer Res., 50, 7717-7722.
2. Banks L, Matlashewski G and Crawford L. (1986). European J. Biochem., 159, 529-534.
3. Bedi A, Pasricha PJ, Akhtar AJ, Barber JP, Bedi GC, Giardiello FM, Zehnbauer BA, Hamilton SR and Jones RJ. (1995). Cancer Res., 55, 1811-1816.
4. Bracey TS, Miller JC, Preece A and Paraskeva C. (1995). Oncogene, 10, 2391-2396.
5. Butt AJ, Hague A and Paraskeva C. (1997). Cell Death and Diff., 4, 725-732.
6. Collins MKL, Furlong IJ, Malade P, Ascaso R, Oliver J and Lopez-Rigas A. (1996). J. Cell Sci., 109, 2393-2399.
7. Desoignie R and Sellin JH. (1994). Gastroenterology, 107, 347-356.
8. Elder DJE, Hague A, Hicks DJ and Paraskeva C. (1996). Cancer Res., 56, 2273-2276.
9. Gavrieli Y, Sherman Y and Bensasson SA. (1992). J. Cell Biol., 119, 493-501.
10. Gerweck LE and Seetharaman K. (1996). Cancer Res., 56, 1194-1198.
11. Gottlieb RA, Giesing HA, Engler RL and Baboir BM. (1995). Blood, 86, 2414-2418.
12. Graeber TG, Osmanian C, Jacks T, Housman DE, Kock CJ, Lowe SW and Giaccia AJ. (1996). Nature, 379, 88-91.
13. Griffiths JR. (1991). Br. J. Cancer, 64, 425-427.
14. Hague A, Bracey TS, Hicks DJ, Reed JC and Paraskeva C. (1998). Carcinogenesis, 19, 1691-1695.
15. Hague A, Manning AM, Hanlon KA, Huschtscha LI, Hart D and Paraskeva C. (1993). Int. J. Cancer, 55, 498-505.
16. Hall PA, Coates PJ, Ansari B and Hopwood D. (1994). J. Cell Sci., 107, 3569-3577.
17. Levine AJ. (1997). Cell, 88, 323-331.
18. Linke SP, Clarkin KC, Dileonardo A, Tsou A and Wahl GM. (1996). Gene Dev., 10, 934-947.
19. Manning AM, Williams AC, Game SM and Paraskeva C. (1991). Oncogene, 6, 1471-1476.
20. Morana S, Li J, Springer EW and Eastman A. (1994). Int. J. Oncol., 5, 153-158.
21. O'Connor PM, Jackman J, Jondle D, Bhatia K, Magrath I and Kohn KW. (1993). Cancer Res., 53, 4776-4780.
22. Paraskeva C, Buckle BG, Sheer D and Wigley CB. (1984). Int. J. Cancer, 34, 49-56.
23. PerezSala D, CulladoEscobar D and Mollinedo F. (1995). J. Biol. Chem., 270, 6235-6242.
24. Reynolds JE, Li J, Craig RW and Eastman A. (1996). Exp. Cell Res., 225, 430-436.
25. Sasaki Y, Hada R, Nakajima H, Fukuda S and Munakata A. (1997). Am. J. Gastro., 92, 114-118.
26. Shemtov MM, Cheng DLW, Kong L, Shu WP, Sassaroli M, Droller and Lui BCS. (1995). J. Urol., 154, 269-274.
27. Tsuji M and Dubois RN. (1995). Cell, 83, 493-501.
28. van der Stappen JWJ, Williams AC, Maciewicz RA and Paraskeva C. (1996). Int. J. Cancer, 67, 547-554.
29. Williams AC, Browne SJ, Yeudal WA. Paterson IC, Marshall CJ, Lane DP and Paraskeva C. (1993). Oncogene, 8, 3063-3072.
30. Williams AC, Miller JC, Collard TJ, Bracey TS, Cosulich S and Paraskeva C. (1995). Oncogene, 11, 141-149.
31. Wolf CM, Morana SJ and Eastman A. (1997). Cell Death and Diff., 4, 125-129.
32. Zoran DL, Barhoumi R, Burghardt RC, Chapkin RS and Lupton JR. (1997). Nutr. Cancer, 27, 222-230.