메뉴 건너뛰기




Volumn 80, Issue 12, 1999, Pages 1892-1897

Acidic environment causes apoptosis by increasing caspase activity

Author keywords

Acidic stress; Apoptosis; Bax; Caspases; PARP cleavage; pH

Indexed keywords

ACID; CASPASE; CASPASE 3; CELL DNA; DNA FRAGMENT; PROTEIN BAX;

EID: 0032788570     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690617     Document Type: Article
Times cited : (161)

References (41)
  • 1
    • 84965835844 scopus 로고
    • The anaerobic and aerobic glycolysis of normal and tumor tissues
    • Academic Press, New York
    • Aisenberg AC (1961) The anaerobic and aerobic glycolysis of normal and tumor tissues, In: The Glycolysis and Respiration of Tumors. pp. 1-53. Academic Press, New York.
    • (1961) The Glycolysis and Respiration of Tumors , pp. 1-53
    • Aisenberg, A.C.1
  • 2
    • 0028881847 scopus 로고
    • DNA-dependent protein kinase is one of a subset of autoantigens specifically cleared early during apoptosis
    • Casciola-Rosen LA, Anhalt GJ and Rosen A (1995) DNA-dependent protein kinase is one of a subset of autoantigens specifically cleared early during apoptosis, J Exp Med 182: 1625-1634
    • (1995) J Exp Med , vol.182 , pp. 1625-1634
    • Casciola-Rosen, L.A.1    Anhalt, G.J.2    Rosen, A.3
  • 3
    • 0023947709 scopus 로고
    • The role of low intracellular or extracellular pH in sensitization to hyperthermia
    • Chu G and Dewey WC (1988) The role of low intracellular or extracellular pH in sensitization to hyperthermia. Radiat Res 114: 154-167
    • (1988) Radiat Res , vol.114 , pp. 154-167
    • Chu, G.1    Dewey, W.C.2
  • 4
    • 0029245192 scopus 로고
    • The bcl-2 gene family
    • Craig RW (1995) The bcl-2 gene family. Semin Cancer Biol 6: 35-43
    • (1995) Semin Cancer Biol , vol.6 , pp. 35-43
    • Craig, R.W.1
  • 5
    • 0029099845 scopus 로고
    • Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B
    • Darmon AJ, Nicholson DW and Bleackley RC (1995) Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Natural 377: 466-448
    • (1995) Natural , vol.377 , pp. 466-1448
    • Darmon, A.J.1    Nicholson, D.W.2    Bleackley, R.C.3
  • 8
    • 0030044324 scopus 로고    scopus 로고
    • ICE AP3, a novel mammalian homologue of the Caenorhabditis elegans cells death protein Ced 3, is activated during Fas- and tumor necrosis factor-induced apoptosis
    • Duan H, Chinnaiyan AM, Hudson PL, Wing JP, He WW and Dixit VM (1996) ICE AP3, a novel mammalian homologue of the Caenorhabditis elegans cells death protein Ced 3, is activated during Fas- and tumor necrosis factor-induced apoptosis. J Biol Chem 271: 1021-1625
    • (1996) J Biol Chem , vol.271 , pp. 1021-1625
    • Duan, H.1    Chinnaiyan, A.M.2    Hudson, P.L.3    Wing, J.P.4    He, W.W.5    Dixit, V.M.6
  • 9
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor/CAD
    • Enari M, Sakahira H, Yokoyama H, Iwamatsa A and Nagata S (1998) A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor/CAD. Nature 391: 43-50
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Iwamatsa, A.4    Nagata, S.5
  • 10
    • 0030985808 scopus 로고    scopus 로고
    • Intracellular acidification induces apoptosis by stimulating ICE-like protease activity
    • Furlong IJ, Ascaso R, Rivas AL and Collins MKL (1997) Intracellular acidification induces apoptosis by stimulating ICE-like protease activity. J Cell Science 110: 653-661
    • (1997) J Cell Science , vol.110 , pp. 653-661
    • Furlong, I.J.1    Ascaso, R.2    Rivas, A.L.3    Collins, M.K.L.4
  • 11
    • 0025771650 scopus 로고
    • Are cancer cells acidic?
    • Griffiths JJ (1991) Are cancer cells acidic? Br J Cancer 64: 425-427
    • (1991) Br J Cancer , vol.64 , pp. 425-427
    • Griffiths, J.J.1
  • 12
    • 0001496579 scopus 로고
    • Extracellular compartments of solid tumors
    • Backer JJ (ed): Cancer, Plenum Press: New York
    • Gullino PM (1975) Extracellular compartments of solid tumors. In Biology of Tumors: Cellular Biology and Growth, Backer JJ (ed) Vol. 3: Cancer, pp. 327-354, Plenum Press: New York.
    • (1975) Biology of Tumors: Cellular Biology and Growth , vol.3 , pp. 327-354
    • Gullino, P.M.1
  • 13
    • 0018612975 scopus 로고
    • The pH of the cytoplasm as an important factor in the survival of vitro cultured malignant cells after hyperthermia. Effects of carbonylcyanide-3-chlorophylhydrazone
    • Haveman J (1979) The pH of the cytoplasm as an important factor in the survival of vitro cultured malignant cells after hyperthermia. Effects of carbonylcyanide-3-chlorophylhydrazone. Eur J Cancer 15: 1281-1288
    • (1979) Eur J Cancer , vol.15 , pp. 1281-1288
    • Haveman, J.1
  • 14
    • 0024348433 scopus 로고
    • Hydrogen ion-mediated enhancement of cytotoxicity of bischlorethylating drug in rat mammary carcionoma cells in vitro
    • Jahde E, Glusenkamp KH, Klunder I, Hulser DF, Tietze LF and Rajewsky MF (1989) Hydrogen ion-mediated enhancement of cytotoxicity of bischlorethylating drug in rat mammary carcionoma cells in vitro. Cancer Res 49: 2965-2972
    • (1989) Cancer Res , vol.49 , pp. 2965-2972
    • Jahde, E.1    Glusenkamp, K.H.2    Klunder, I.3    Hulser, D.F.4    Tietze, L.F.5    Rajewsky, M.F.6
  • 15
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly(ADP)-ribose polymerase: An early marker of chemotherapy-induced apoptosis
    • Kaufmann SH, Desnoyers S, Ottaviano Y, Davidson NE and Poirier GG (1993) Specific proteolytic cleavage of poly(ADP)-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res 53: 3976-3985
    • (1993) Cancer Res , vol.53 , pp. 3976-3985
    • Kaufmann, S.H.1    Desnoyers, S.2    Ottaviano, Y.3    Davidson, N.E.4    Poirier, G.G.5
  • 17
    • 0029794385 scopus 로고    scopus 로고
    • The ICE family of cysteine proteases as effectors of cell death
    • Kumar S and Lavin MF (1996) The ICE family of cysteine proteases as effectors of cell death. Cell Death Differ 3: 255-267
    • (1996) Cell Death Differ , vol.3 , pp. 255-267
    • Kumar, S.1    Lavin, M.F.2
  • 18
    • 0028102478 scopus 로고
    • Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE
    • Lazebnik YA, Kaufman SH, Desnoyers S, Poirier GG and Earnshaw WC (1994) Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371: 346-347
    • (1994) Nature , vol.371 , pp. 346-347
    • Lazebnik, Y.A.1    Kaufman, S.H.2    Desnoyers, S.3    Poirier, G.G.4    Earnshaw, W.C.5
  • 20
    • 0029061847 scopus 로고
    • Modification of intracellular pH and thermotolerance development by amiloride
    • Liu JCK and Fox MH (1995) Modification of intracellular pH and thermotolerance development by amiloride. Int J Hyperthermia 11: 511-523
    • (1995) Int J Hyperthermia , vol.11 , pp. 511-523
    • Liu, J.C.K.1    Fox, M.H.2
  • 21
    • 0030040930 scopus 로고    scopus 로고
    • The relationship between intracellular pH and heat sensitivity in a thermoresistant cell line
    • Liu F-F, Sherar MD and Hill RP (1996) The relationship between intracellular pH and heat sensitivity in a thermoresistant cell line. Radiat Res 145: 144-149
    • (1996) Radiat Res , vol.145 , pp. 144-149
    • Liu, F.-F.1    Sherar, M.D.2    Hill, R.P.3
  • 22
    • 0027769836 scopus 로고
    • The effect of the chemotherapeutic drug VP-16 on poly(ADP-ribosylation) in apoptotic HeLa cells
    • Negri C, Bernardi R, Braghetti A, Ricotti GC and Scovassi AI (1993) The effect of the chemotherapeutic drug VP-16 on poly(ADP-ribosylation) in apoptotic HeLa cells. Carcinogenesis 14: 2559-2564
    • (1993) Carcinogenesis , vol.14 , pp. 2559-2564
    • Negri, C.1    Bernardi, R.2    Braghetti, A.3    Ricotti, G.C.4    Scovassi, A.I.5
  • 24
    • 0029989610 scopus 로고    scopus 로고
    • Effect of intracellular acidity and ionomycin on apoptosis in HL-60 cells
    • Park HJ, Makepeace CM, Lyons JC and Song CW (1996) Effect of intracellular acidity and ionomycin on apoptosis in HL-60 cells. Eur J Cancer 32A: 540-546
    • (1996) Eur J Cancer , vol.32 A , pp. 540-546
    • Park, H.J.1    Makepeace, C.M.2    Lyons, J.C.3    Song, C.W.4
  • 26
    • 0031889132 scopus 로고    scopus 로고
    • Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
    • Sakahira H, Enari M and Nagata S (1998) Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391: 96-99
    • (1998) Nature , vol.391 , pp. 96-99
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 29
    • 0002639767 scopus 로고
    • Intra- and extracellular pH in solid tumors: Influence on therapeutic response. In
    • B Teicher (ed). Marcel Dekker: New York
    • Song CW, Lyons JC and Luo Y (1993b) Intra- and extracellular pH in solid tumors: Influence on therapeutic response. In: Drug Resistance in Oncolgy, B Teicher (ed), pp. 25-51. Marcel Dekker: New York
    • (1993) Drug Resistance in Oncolgy , pp. 25-51
    • Song, C.W.1    Lyons, J.C.2    Luo, Y.3
  • 33
    • 0032525874 scopus 로고    scopus 로고
    • Apoptosis and perturbation of cell cycle progression in an acidic environment after hyperthermia
    • Takasu T, Lyons JC, Park HJ and Song CW (1998) Apoptosis and perturbation of cell cycle progression in an acidic environment after hyperthermia. Cancer Res 58: 2504-2508
    • (1998) Cancer Res , vol.58 , pp. 2504-2508
    • Takasu, T.1    Lyons, J.C.2    Park, H.J.3    Song, C.W.4
  • 34
    • 0024379967 scopus 로고
    • Acid pH in tumors and its potential for therapeutic exploitation
    • Tannock IF and Rotin D (1989) Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res 49: 4373-4384
    • (1989) Cancer Res , vol.49 , pp. 4373-4384
    • Tannock, I.F.1    Rotin, D.2
  • 36
    • 0021732164 scopus 로고
    • The relevance of tumour pH to the treatment of malignant disease
    • Wike-Hooley JL, Haveman J and Reinbold HS (1984) The relevance of tumour pH to the treatment of malignant disease. Radiother Oncol 2: 344-366
    • (1984) Radiother Oncol , vol.2 , pp. 344-366
    • Wike-Hooley, J.L.1    Haveman, J.2    Reinbold, H.S.3
  • 37
    • 0031561725 scopus 로고    scopus 로고
    • The temporal relationship between protein phosphatase, ICE/CED-3 proteases, intracellular acidification, and DNA fragmentation in apoptosis
    • Wolf CM, Reynolds JE, Morana SJ and Eastman A (1997) The temporal relationship between protein phosphatase, ICE/CED-3 proteases, intracellular acidification, and DNA fragmentation in apoptosis. Exp Cell Res 230: 22-27
    • (1997) Exp Cell Res , vol.230 , pp. 22-27
    • Wolf, C.M.1    Reynolds, J.E.2    Morana, S.J.3    Eastman, A.4
  • 38
    • 0001606206 scopus 로고
    • Major deletions in the gene encoding the p53 tumor antigen causes lack of p53 expression in HL-60 cells
    • Wolf D and Rolter V (1985) Major deletions in the gene encoding the p53 tumor antigen causes lack of p53 expression in HL-60 cells. Proc Natl Acad Sci USA 82: 790-794
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 790-794
    • Wolf, D.1    Rolter, V.2
  • 39
    • 0032525332 scopus 로고    scopus 로고
    • 2+-dependent endonuclease (AN34) from etoposide-treated human leukemia HL-60 cells undergoing apoptosis
    • 2+-dependent endonuclease (AN34) from etoposide-treated human leukemia HL-60 cells undergoing apoptosis. Cancer Res 58: 2576-2582
    • (1998) Cancer Res , vol.58 , pp. 2576-2582
    • Yoshida, A.1    Pourquier, P.2    Pommier, Y.3
  • 41
    • 0032126479 scopus 로고    scopus 로고
    • Death of tumor cells after intracellular acidification is dependent on stress-activated protein kinases (SAPK/JNK) pathway activation and cannot be inhibited by Bcl-2 expression or interleukin 1 β-converting enzyme inhibition
    • Zanke BW, Lee C, Arab S and Tannock IF (1998) Death of tumor cells after intracellular acidification is dependent on stress-activated protein kinases (SAPK/JNK) pathway activation and cannot be inhibited by Bcl-2 expression or interleukin 1 β-converting enzyme inhibition. Cancer Res 58: 2801-2808
    • (1998) Cancer Res , vol.58 , pp. 2801-2808
    • Zanke, B.W.1    Lee, C.2    Arab, S.3    Tannock, I.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.