HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity

Cancer Cell

Volumn 11, Issue 5, 2007, Pages 407-420

  Zhang, Huafeng ^a   Gao, Ping ^a   Fukuda, Ryo ^a   Kumar, Ganesh ^b   Krishnamachary, Balaji ^a   Zeller, Karen I ^a   Dang, Chi V ^a   Semenza, Gregg L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

CELLCYCLE

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; TRANSCRIPTION FACTOR; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

ARTICLE; BIOGENESIS; CANCER INHIBITION; CELL RESPIRATION; CONTROLLED STUDY; ENERGY METABOLISM; GENE ACTIVITY; GENE REPRESSION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; NUCLEOTIDE SEQUENCE; ONCOGENE C MYC; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 34247614521     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2007.04.001     Document Type: Article

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