-
1
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
Review; 214 references
-
Vaupel P, Kallinowski F, and Okunieff P (1989). Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 49, 6449-65 [Review; 214 references].
-
(1989)
Cancer Res
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
2
-
-
0025880555
-
2H nuclear magnetic resonance studies
-
2H nuclear magnetic resonance studies. Cancer Res 51, 3289-95.
-
(1991)
Cancer Res
, vol.51
, pp. 3289-3295
-
-
Okunieff, P.1
Dols, S.2
Lee, J.3
Singer, S.4
Vaupel, P.5
Neuringer, L.J.6
Beshah, K.7
-
3
-
-
0021732164
-
The relevance of tumour pH to the treatment of malignant disease
-
Wike-Hooley JL, Haveman J, and Reinhold HS (1984). The relevance of tumour pH to the treatment of malignant disease. Radiother Oncol 2, 343-66.
-
(1984)
Radiother Oncol
, vol.2
, pp. 343-366
-
-
Wike-Hooley, J.L.1
Haveman, J.2
Reinhold, H.S.3
-
4
-
-
0025771650
-
Are cancer cells acidic?
-
Griffiths JR (1991). Are cancer cells acidic? Br J Cancer 64, 425-27.
-
(1991)
Br J Cancer
, vol.64
, pp. 425-427
-
-
Griffiths, J.R.1
-
5
-
-
0028465482
-
31p-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate
-
31p-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. Am J Physiol 267, t-203.
-
(1994)
Am J Physiol
, vol.267
-
-
Gillies, R.J.1
Liu, Z.2
Bhujwalla, Z.3
-
6
-
-
0032942766
-
1H MRSI
-
1H MRSI. Magn Reson Med 41, 743-50.
-
(1999)
Magn Reson Med
, vol.41
, pp. 743-750
-
-
Van Sluis, R.1
Bhujwalla, Z.M.2
Raghunand, N.3
Ballesteros, P.4
Alvarez, J.5
Cerdan, S.6
Galons, J.P.7
Gillies, R.J.8
-
7
-
-
0032565578
-
Mutagenesis induced by the tumor microenvironment
-
Review; 47 references
-
Yuan J, and Glazer PM (1998). Mutagenesis induced by the tumor microenvironment. Mutat Res 400, 439-46 [Review; 47 references].
-
(1998)
Mutat Res
, vol.400
, pp. 439-446
-
-
Yuan, J.1
Glazer, P.M.2
-
8
-
-
0034662615
-
Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH
-
Yuan J, Narayanan L, Rockwell S, and Glazer PM (2000). Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH. Cancer Res 60, 4372-76.
-
(2000)
Cancer Res
, vol.60
, pp. 4372-4376
-
-
Yuan, J.1
Narayanan, L.2
Rockwell, S.3
Glazer, P.M.4
-
9
-
-
0026623304
-
Clastogenicity of low pH to various cultured mammalian cells
-
Morita T, Nagaki T, Fukuda I, and Okumura K (1992). Clastogenicity of low pH to various cultured mammalian cells. Mutat Res 268, 297-305.
-
(1992)
Mutat Res
, vol.268
, pp. 297-305
-
-
Morita, T.1
Nagaki, T.2
Fukuda, I.3
Okumura, K.4
-
10
-
-
0025302535
-
Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.70
-
LeBoeuf RA, Kerckaert GA, Aardema MJ, and Gibson DP (1990). Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.70. Cancer Res 59, 3722-29.
-
(1990)
Cancer Res
, vol.59
, pp. 3722-3729
-
-
LeBoeuf, R.A.1
Kerckaert, G.A.2
Aardema, M.J.3
Gibson, D.P.4
-
11
-
-
0035866784
-
Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation
-
Chen EY, Mazure NM, Cooper JA, and Giaccia AJ (2001). Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation. Cancer Res 61, 2429-33.
-
(2001)
Cancer Res
, vol.61
, pp. 2429-2433
-
-
Chen, E.Y.1
Mazure, N.M.2
Cooper, J.A.3
Giaccia, A.J.4
-
12
-
-
0036194956
-
Combined vascular and extracellular pH imaging of solid tumors
-
Bhujwalla ZM, Artemov D, Ballesteros P, Cerdan S, Gillies RJ, and Solaiyappan M (2002). Combined vascular and extracellular pH imaging of solid tumors. NMR Biomed 15 (2), 114-19.
-
(2002)
NMR Biomed
, vol.15
, Issue.2
, pp. 114-119
-
-
Bhujwalla, Z.M.1
Artemov, D.2
Ballesteros, P.3
Cerdan, S.4
Gillies, R.J.5
Solaiyappan, M.6
-
13
-
-
0029982979
-
Acidic pH enhances the invasive behavior of human melanoma cells
-
Martinez-Zaguilan R, Seftor EA, Seftor REB, Chu Y-W, Gillies RJ, and Hendrix MJC (1996). Acidic pH enhances the invasive behavior of human melanoma cells. Clin Ex Metastasis 14, 176-86.
-
(1996)
Clin Ex Metastasis
, vol.14
, pp. 176-186
-
-
Martinez-Zaguilan, R.1
Seftor, E.A.2
Seftor, R.E.B.3
Chu, Y.-W.4
Gillies, R.J.5
Hendrix, M.J.C.6
-
14
-
-
0028618307
-
Pericellular pH affects distribution and secretion of cathepsin B in malignant cells
-
Rozhin J, Sameni M, Ziegler G, and Sloane BF (1994). Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. Cancer Res 54, 6517-25.
-
(1994)
Cancer Res
, vol.54
, pp. 6517-6525
-
-
Rozhin, J.1
Sameni, M.2
Ziegler, G.3
Sloane, B.F.4
-
15
-
-
0025771024
-
Glucose starvation and acidosis: Effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells
-
Schlappack OK, Zimmermann A, and Hill RP (1991). Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells. Br J Cancer 64, 663-70.
-
(1991)
Br J Cancer
, vol.64
, pp. 663-670
-
-
Schlappack, O.K.1
Zimmermann, A.2
Hill, R.P.3
-
16
-
-
0032904346
-
Enhancement of chemotherapy by manipulation of tumour pH
-
Raghunand N, He X, van Sluis R, Mahoney B, Baggett B, Taylor CW, Paine-Murrieta G, Roe D, Bhujwalla ZM, and Gillies RJ (1999). Enhancement of chemotherapy by manipulation of tumour pH. Br J Cancer 80, 1005-11.
-
(1999)
Br J Cancer
, vol.80
, pp. 1005-1011
-
-
Raghunand, N.1
He, X.2
Van Sluis, R.3
Mahoney, B.4
Baggett, B.5
Taylor, C.W.6
Paine-Murrieta, G.7
Roe, D.8
Bhujwalla, Z.M.9
Gillies, R.J.10
-
17
-
-
0034884690
-
Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone
-
Raghunand N, Mahoney B, van Sluis R, Baggett B, and Gillies RJ (2001). Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone. Neoplasia 3, 227-35.
-
(2001)
Neoplasia
, vol.3
, pp. 227-235
-
-
Raghunand, N.1
Mahoney, B.2
Van Sluis, R.3
Baggett, B.4
Gillies, R.J.5
-
18
-
-
0029948108
-
Microvascular studies on the origins of perfusion-limited hypoxia
-
Dewhirst MW, Kimura H, Rehmus SW, Braun RD, Papahadjopoulos D, Hong K, and Secomb TW (1996). Microvascular studies on the origins of perfusion-limited hypoxia. Br J Cancer Suppl 27, S247-51.
-
(1996)
Br J Cancer Suppl
, vol.27
-
-
Dewhirst, M.W.1
Kimura, H.2
Rehmus, S.W.3
Braun, R.D.4
Papahadjopoulos, D.5
Hong, K.6
Secomb, T.W.7
-
19
-
-
0033170557
-
Causes and effects of heterogeneous perfusion in tumors
-
Review; 161 references
-
Gillies RJ, Schornack PA, Secomb TW, and Raghunand N (1999). Causes and effects of heterogeneous perfusion in tumors. Neoplasia 1, 197-207 [Review; 161 references].
-
(1999)
Neoplasia
, vol.1
, pp. 197-207
-
-
Gillies, R.J.1
Schornack, P.A.2
Secomb, T.W.3
Raghunand, N.4
-
20
-
-
0037112366
-
Overexpression of vascular endothelial growth factor 165 drives peritumor interstitial convection and induces lymphatic drain: Magnetic resonance imaging, confocal microscopy, and histological tracking of triple-labeled albumin
-
Dafni HI (2002). Overexpression of vascular endothelial growth factor 165 drives peritumor interstitial convection and induces lymphatic drain: magnetic resonance imaging, confocal microscopy, and histological tracking of triple-labeled albumin. Cancer Res 62, 6731-39.
-
(2002)
Cancer Res
, vol.62
, pp. 6731-6739
-
-
Dafni, H.I.1
-
21
-
-
84966192535
-
The histological structure of some human lung cancers and the possible implications for radiotherapy
-
Thomlinson RH, and Gray LH (1955). The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer 9, 539-49.
-
(1955)
Br J Cancer
, vol.9
, pp. 539-549
-
-
Thomlinson, R.H.1
Gray, L.H.2
-
22
-
-
0018286639
-
Oxygen diffusion distance and development of necrosis in multicell spheroids
-
Franko AJ, and Sutherland RM (1979). Oxygen diffusion distance and development of necrosis in multicell spheroids. Radiat Res 79, 439-53.
-
(1979)
Radiat Res
, vol.79
, pp. 439-453
-
-
Franko, A.J.1
Sutherland, R.M.2
-
23
-
-
0032415845
-
Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels
-
Secomb TW, Hsu R, Braun RD, Ross JR, Gross JF, and Dewhirst MW (1998). Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels. Adv Exp Med Biol 454, 629-34.
-
(1998)
Adv Exp Med Biol
, vol.454
, pp. 629-634
-
-
Secomb, T.W.1
Hsu, R.2
Braun, R.D.3
Ross, J.R.4
Gross, J.F.5
Dewhirst, M.W.6
-
24
-
-
0030614893
-
2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
-
2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nature 3, 177-82.
-
(1997)
Nature
, vol.3
, pp. 177-182
-
-
Helmlinger, G.1
Yuan, F.2
Jain, M.D.3
Jain, R.4
-
25
-
-
0032927078
-
31p magnetic resonance spectroscopy
-
31p magnetic resonance spectroscopy. Biochem Pharmacol 57, 309-12.
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 309-312
-
-
Raghunand, N.1
Altbach, M.I.2
Van Sluis, R.3
Baggett, B.4
Taylor, C.W.5
Bhujwalla, Z.M.6
Gillies, R.J.7
-
27
-
-
0023119889
-
Effect of fixed or mobile buffer ions on proton mobility
-
Junge W, and McLaughlin S (1987). Effect of fixed or mobile buffer ions on proton mobility. Biochim Biophys Acta 890, 1-5.
-
(1987)
Biochim Biophys Acta
, vol.890
, pp. 1-5
-
-
Junge, W.1
McLaughlin, S.2
-
28
-
-
0028058177
-
Time-dependent diffusion of water in a biological model system
-
Latour LL, Svoboda K, Mitra PP, and Sotak CH (1994). Time-dependent diffusion of water in a biological model system. Proc Natl Acad Sci USA 91, 1229-33.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1229-1233
-
-
Latour, L.L.1
Svoboda, K.2
Mitra, P.P.3
Sotak, C.H.4
-
29
-
-
0016193990
-
Buffer-facilitated proton transport pH profile of bound enzymes
-
Engasser JM, and Horvath C (1974). Buffer-facilitated proton transport pH profile of bound enzymes. Biochim Biophys Acta 358, 178-92.
-
(1974)
Biochim Biophys Acta
, vol.358
, pp. 178-192
-
-
Engasser, J.M.1
Horvath, C.2
-
30
-
-
11744384413
-
The Grotthuss mechanism
-
Agmon N (2002). The Grotthuss mechanism. Chem Phys Lett 244, 456-62.
-
(2002)
Chem Phys Lett
, vol.244
, pp. 456-462
-
-
Agmon, N.1
-
31
-
-
0025047493
-
Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions
-
Gillies RJ, Martinez-Zaguilan R, Martinez GM, Serrano R, and Perona R (1990). Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions. Proc Natl Acad Sci USA 87, 7414-18.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7414-7418
-
-
Gillies, R.J.1
Martinez-Zaguilan, R.2
Martinez, G.M.3
Serrano, R.4
Perona, R.5
-
32
-
-
0000575007
-
A stirred bath technique for diffusivity measurements in cell matrices
-
Chresand TJ, Dale BE, Hanson SL, and Gillies RJ (1988). A stirred bath technique for diffusivity measurements in cell matrices. Biotechnol Bioeng 32, 1029-36.
-
(1988)
Biotechnol Bioeng
, vol.32
, pp. 1029-1036
-
-
Chresand, T.J.1
Dale, B.E.2
Hanson, S.L.3
Gillies, R.J.4
-
34
-
-
0003880161
-
-
Garland Publishing, New York and London
-
Alberts B, Bray D, Lewis J, Raff M, Roberts K, and Watson JD (1994). Molecular Biology of the Cell. Garland Publishing, New York and London.
-
(1994)
Molecular Biology of the Cell
-
-
Alberts, B.1
Bray, D.2
Lewis, J.3
Raff, M.4
Roberts, K.5
Watson, J.D.6
-
35
-
-
0035021707
-
A tabulated summary of the FDG PET literature
-
Gambhir SS, Czernin J, Schwimmer J, Silverman DH, Coleman RE, and Phelps ME (2001). A tabulated summary of the FDG PET literature. J Nucl Med 42, 1S-93S.
-
(2001)
J Nucl Med
, vol.42
-
-
Gambhir, S.S.1
Czernin, J.2
Schwimmer, J.3
Silverman, D.H.4
Coleman, R.E.5
Phelps, M.E.6
-
36
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O (1956). On the origin of cancer cells. Science 123, 309-314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
37
-
-
0019883373
-
Warburg effect revisited: Merger of biochemistry and molecular biology
-
Racker E, and Spector M (1981). Warburg effect revisited: merger of biochemistry and molecular biology. Science 213, 303-307.
-
(1981)
Science
, vol.213
, pp. 303-307
-
-
Racker, E.1
Spector, M.2
-
38
-
-
0036554644
-
Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism
-
Helmlinger G, Sckell A, Dellian M, Forbes NS, and Jain RK (2002). Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism. Clin Cancer Res 8, 1284-91.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1284-1291
-
-
Helmlinger, G.1
Sckell, A.2
Dellian, M.3
Forbes, N.S.4
Jain, R.K.5
-
39
-
-
0024308302
-
Reduction of intracellular pH as a possible mechanism for killing cells in acidic regions of solid tumors: Effects of carbonylcyanide-3-chlorophenylhydrazone
-
Newell KJ, and Tannock IF (1989). Reduction of intracellular pH as a possible mechanism for killing cells in acidic regions of solid tumors: effects of carbonylcyanide-3-chlorophenylhydrazone. Cancer Res 49, 4477-82.
-
(1989)
Cancer Res
, vol.49
, pp. 4477-4482
-
-
Newell, K.J.1
Tannock, I.F.2
-
40
-
-
0031748828
-
The contribution of lactic acid to acidification of tumours: Studies of variant cells lacking lactate dehydrogenase
-
Yamagata M, Hasuda K, Stamato T, and Tannock IF (1998). The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase. Br J Cancer 77, 1726-31.
-
(1998)
Br J Cancer
, vol.77
, pp. 1726-1731
-
-
Yamagata, M.1
Hasuda, K.2
Stamato, T.3
Tannock, I.F.4
-
41
-
-
0033179481
-
Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes
-
Ainscow EK, and Brand MD (1999). Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. Eur J Biochem 263, 671-85.
-
(1999)
Eur J Biochem
, vol.263
, pp. 671-685
-
-
Ainscow, E.K.1
Brand, M.D.2
-
42
-
-
0034687243
-
Metabolic control: A new solution to an old problem
-
Hardie DG (2000). Metabolic control: a new solution to an old problem. Curr Biol 10, 757-59.
-
(2000)
Curr Biol
, vol.10
, pp. 757-759
-
-
Hardie, D.G.1
-
43
-
-
0034687210
-
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia
-
Marsin AS, Bertrand L, Rider MH, Deprez J, Beauloye C, Vincint MF, van den Berghe G, Carling D, and Julius D (2000). Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia. Curr Biol 10, 1247-55.
-
(2000)
Curr Biol
, vol.10
, pp. 1247-1255
-
-
Marsin, A.S.1
Bertrand, L.2
Rider, M.H.3
Deprez, J.4
Beauloye, C.5
Vincint, M.F.6
Van den Berghe, G.7
Carling, D.8
Julius, D.9
-
44
-
-
0035027828
-
Transcription factor HIF-1 is a necessary mediator of the Pasteur effect in mammalian cells
-
Seagroves T, Ryan HE, Lu H, Wouters BG, Knapp AG, Thibault P, Laderoute K, and Johnson RS (2001). Transcription factor HIF-1 is a necessary mediator of the Pasteur effect in mammalian cells. Mol Cell Biol 21, 3436-44.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3436-3444
-
-
Seagroves, T.1
Ryan, H.E.2
Lu, H.3
Wouters, B.G.4
Knapp, A.G.5
Thibault, P.6
Laderoute, K.7
Johnson, R.S.8
-
45
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
-
Zhong H, De Marzo AM, Laughner E, Lim M, Hilton DA, Zagzag D, Buechler P, Isaacs WB, Semenza GL, and Simons JW (1999). Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res 59, 5830-35.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
Buechler, P.7
Isaacs, W.B.8
Semenza, G.L.9
Simons, J.W.10
-
46
-
-
0001620276
-
Current pulses involving chloride and potassium efflux relieve pressure in pelvetia embryos
-
Nuccitelli R, and Jaffe LF (1976). Current pulses involving chloride and potassium efflux relieve pressure in pelvetia embryos. Planta (Berlin) 131, 315-20.
-
(1976)
Planta (Berlin)
, vol.131
, pp. 315-320
-
-
Nuccitelli, R.1
Jaffe, L.F.2
-
47
-
-
0016945107
-
The ionic components of the current pulses generated by developing fucoid eggs
-
Nuccitelli R, and Jaffe LF (1976). The ionic components of the current pulses generated by developing fucoid eggs. Dev Biol 49, 518-31.
-
(1976)
Dev Biol
, vol.49
, pp. 518-531
-
-
Nuccitelli, R.1
Jaffe, L.F.2
|