메뉴 건너뛰기




Volumn 7, Issue 4, 2005, Pages 324-330

Hypoxia-inducible factor-1α and the glycolytic phenotype in tumors

Author keywords

Glucose consumption; Glycolysis; Hypoxia inducible factor; Lactate; Warburg effect

Indexed keywords

GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; VON HIPPEL LINDAU PROTEIN;

EID: 18644366801     PISSN: 15228002     EISSN: None     Source Type: Journal    
DOI: 10.1593/neo.04430     Document Type: Article
Times cited : (215)

References (41)
  • 1
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O (1956). On the origin of cancer cells. Science 123, 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 2
    • 0036176751 scopus 로고    scopus 로고
    • Positron emission tomography scanning: Current and future applications
    • Czernin J and Phelps ME (2002). Positron emission tomography scanning: current and future applications. Annu Rev Med 53, 89-112.
    • (2002) Annu Rev Med , vol.53 , pp. 89-112
    • Czernin, J.1    Phelps, M.E.2
  • 4
    • 8844224030 scopus 로고    scopus 로고
    • Microenvironmental and cellular consequences of altered blood flow in tumors
    • Raghunand N, Gatenby RA, and Gillies RJ (2003). Microenvironmental and cellular consequences of altered blood flow in tumors. Br J Radiol 76, S11-S22.
    • (2003) Br J Radiol , vol.76
    • Raghunand, N.1    Gatenby, R.A.2    Gillies, R.J.3
  • 5
    • 0037335608 scopus 로고    scopus 로고
    • A mathematical model of tumor oxygen and glucose mass transport and metabolism with complex reaction kinetics
    • Kirkpatrick JP, Brizel DM, and Dewhirst MW (2003). A mathematical model of tumor oxygen and glucose mass transport and metabolism with complex reaction kinetics. Radiat Res 159, 336-344.
    • (2003) Radiat Res , vol.159 , pp. 336-344
    • Kirkpatrick, J.P.1    Brizel, D.M.2    Dewhirst, M.W.3
  • 6
    • 0030476061 scopus 로고    scopus 로고
    • Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma
    • Kimura H, Braun RD, Ong ET, Hsu R, Secomb TW, Papahadjopoulos D, Hong K, and Dewhirst MW (1996). Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma. Cancer Res 56, 5522-5528.
    • (1996) Cancer Res , vol.56 , pp. 5522-5528
    • Kimura, H.1    Braun, R.D.2    Ong, E.T.3    Hsu, R.4    Secomb, T.W.5    Papahadjopoulos, D.6    Hong, K.7    Dewhirst, M.W.8
  • 7
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis - Correlation in invasive breast carcinoma
    • Weidner N, Semple JP, Welch WR, and Folkman J (1991). Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma. N Engl J Med 324, 1-8.
    • (1991) N Engl J Med , vol.324 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 8
    • 0030935836 scopus 로고    scopus 로고
    • Tumour angiogenesis and prognosis
    • Fox SB (1997). Tumour angiogenesis and prognosis. Histopathology 30, 294-301.
    • (1997) Histopathology , vol.30 , pp. 294-301
    • Fox, S.B.1
  • 10
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza GL and Wang GL (1992). A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12, 5447-5454.
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 13
    • 0035812772 scopus 로고    scopus 로고
    • HIF-1, O(2), and the 3 PHDs: How animal cells signal hypoxia to the nucleus
    • Semenza GL (2001). HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell 107, 1-3.
    • (2001) Cell , vol.107 , pp. 1-3
    • Semenza, G.L.1
  • 16
    • 0028068606 scopus 로고
    • Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
    • Semenza GL, Roth PH, Fang HM, and Wang GL (1994). Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 269, 23757-23763.
    • (1994) J Biol Chem , vol.269 , pp. 23757-23763
    • Semenza, G.L.1    Roth, P.H.2    Fang, H.M.3    Wang, G.L.4
  • 17
    • 0028805375 scopus 로고
    • Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct asacting sequences
    • Ebert BL, Firth JD, and Ratcliffe PJ (1995). Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct asacting sequences. J Biol Chem 270, 29083-29089.
    • (1995) J Biol Chem , vol.270 , pp. 29083-29089
    • Ebert, B.L.1    Firth, J.D.2    Ratcliffe, P.J.3
  • 20
    • 0029039195 scopus 로고
    • Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
    • Levy AP, Levy NS, Wegner S, and Goldberg MA (1995). Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem 270, 13333-13340.
    • (1995) J Biol Chem , vol.270 , pp. 13333-13340
    • Levy, A.P.1    Levy, N.S.2    Wegner, S.3    Goldberg, M.A.4
  • 21
    • 0028019589 scopus 로고
    • Regulation of erythropoietin production. New insights into molecular mechanisms of oxygen homeostasis
    • Semenza GL (1994). Regulation of erythropoietin production. New insights into molecular mechanisms of oxygen homeostasis. Hematol Oncol Clin North Am 8, 863-884.
    • (1994) Hematol Oncol Clin North Am , vol.8 , pp. 863-884
    • Semenza, G.L.1
  • 25
    • 2442701892 scopus 로고    scopus 로고
    • Lineage infidelity of MDA-MB-435 cells: Expression of melanocyte proteins in a breast cancer cell line
    • Sellappan S, Grijalva R, Zhou X, Yang W, Eli MB, Mills GB, and Yu D (2004). Lineage infidelity of MDA-MB-435 cells: expression of melanocyte proteins in a breast cancer cell line. Cancer Res 64, 3479-3485.
    • (2004) Cancer Res , vol.64 , pp. 3479-3485
    • Sellappan, S.1    Grijalva, R.2    Zhou, X.3    Yang, W.4    Eli, M.B.5    Mills, G.B.6    Yu, D.7
  • 27
    • 0344608877 scopus 로고    scopus 로고
    • Dominant-negative hypoxia-inducible factor-1 alpha reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism
    • Chen J, Zhao S, Nakada K, Kuge Y, Tamaki N, Okada F, Wang J, Shindo M, Higashino F, Takeda K, et al. (2003). Dominant-negative hypoxia-inducible factor-1 alpha reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism. Am J Pathol 162, 1283-1291.
    • (2003) Am J Pathol , vol.162 , pp. 1283-1291
    • Chen, J.1    Zhao, S.2    Nakada, K.3    Kuge, Y.4    Tamaki, N.5    Okada, F.6    Wang, J.7    Shindo, M.8    Higashino, F.9    Takeda, K.10
  • 28
    • 4444369682 scopus 로고    scopus 로고
    • Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha
    • Welsh S, Williams R, Kirkpatrick L, Paine-Murrieta G, and Powis G (2004). Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha. Mol Cancer Ther 3, 233-244.
    • (2004) Mol Cancer Ther , vol.3 , pp. 233-244
    • Welsh, S.1    Williams, R.2    Kirkpatrick, L.3    Paine-Murrieta, G.4    Powis, G.5
  • 32
    • 0035077154 scopus 로고    scopus 로고
    • Von Hippel-Lindau tumour suppressor gene is not involved in sporadic human breast cancer
    • Sourvinos G, Miyakis S, Liloglou TL, Field JK, and Spandidos DA (2001). Von Hippel-Lindau tumour suppressor gene is not involved in sporadic human breast cancer. Tumour Biol 22, 131-136.
    • (2001) Tumour Biol , vol.22 , pp. 131-136
    • Sourvinos, G.1    Miyakis, S.2    Liloglou, T.L.3    Field, J.K.4    Spandidos, D.A.5
  • 33
    • 0037131271 scopus 로고    scopus 로고
    • Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha
    • Chan DA, Sutphin PD, Denko NC, and Giaccia AJ (2002). Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha. J Biol Chem 277, 40112-40117.
    • (2002) J Biol Chem , vol.277 , pp. 40112-40117
    • Chan, D.A.1    Sutphin, P.D.2    Denko, N.C.3    Giaccia, A.J.4
  • 34
    • 0037044578 scopus 로고    scopus 로고
    • Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia
    • Karni R, Dor Y, Keshet E, Meyuhas O, and Levitzki A (2002). Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia. J Biol Chem 277, 42919-42925.
    • (2002) J Biol Chem , vol.277 , pp. 42919-42925
    • Karni, R.1    Dor, Y.2    Keshet, E.3    Meyuhas, O.4    Levitzki, A.5
  • 36
    • 0037119415 scopus 로고    scopus 로고
    • Hsp90 regulates a von Hippel Lindau - Independent hypoxia-inducible factor-1 alpha-degradative pathway
    • Isaacs JS, Jung YJ, Mimnaugh EG, Martinez A, Cuttitta F, and Neckers LM (2002). Hsp90 regulates a von Hippel Lindau - independent hypoxia-inducible factor-1 alpha-degradative pathway. J Biol Chem 277, 29936-29944.
    • (2002) J Biol Chem , vol.277 , pp. 29936-29944
    • Isaacs, J.S.1    Jung, Y.J.2    Mimnaugh, E.G.3    Martinez, A.4    Cuttitta, F.5    Neckers, L.M.6
  • 37
    • 0037189542 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis
    • Lu H, Forbes RA, and Verma A (2002). Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis. J Biol Chem 277, 23111-23115.
    • (2002) J Biol Chem , vol.277 , pp. 23111-23115
    • Lu, H.1    Forbes, R.A.2    Verma, A.3
  • 39
    • 0042242676 scopus 로고    scopus 로고
    • The glycolytic phenotype in carcinogenesis and tumor invasion: Insights through mathematical models
    • Gatenby RA and Gawlinski ET (2003). The glycolytic phenotype in carcinogenesis and tumor invasion: insights through mathematical models. Cancer Res 63, 3847-3854.
    • (2003) Cancer Res , vol.63 , pp. 3847-3854
    • Gatenby, R.A.1    Gawlinski, E.T.2
  • 40
    • 0030499036 scopus 로고    scopus 로고
    • Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia
    • Berggren M, Gallegos A, Gasdaska JR, Gasdaska PY, Warneke J, and Powis G (1996). Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia. Anticancer Res 16, 3459-3466.
    • (1996) Anticancer Res , vol.16 , pp. 3459-3466
    • Berggren, M.1    Gallegos, A.2    Gasdaska, J.R.3    Gasdaska, P.Y.4    Warneke, J.5    Powis, G.6
  • 41
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW (2001). A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29, e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.