-
1
-
-
28544442609
-
Protein translocation across biological membranes
-
PMID:16322447
-
Wickner W, Schekman R. Protein translocation across biological membranes. Science 2005; 310:1452-6; PMID:16322447; http://dx.doi.org/10.1126/science.1113752
-
(2005)
Science
, vol.310
, pp. 1452-1456
-
-
Wickner, W.1
Schekman, R.2
-
2
-
-
35748948975
-
In and out of the ER: Protein folding, quality control, degradation, and related human diseases
-
PMID:17928587
-
Hebert DN, Molinari M. In and out of the ER: protein folding, quality control, degradation, and related human diseases. Physiol Rev 2007; 87:1377-408; PMID:17928587; http://dx.doi.org/10.1152/physrev.00050.2006
-
(2007)
Physiol Rev
, vol.87
, pp. 1377-1408
-
-
Hebert, D.N.1
Molinari, M.2
-
3
-
-
10444226462
-
ER stress and the unfolded protein response
-
PMID:15603751
-
Schroder M, Kaufman RJ. ER stress and the unfolded protein response. Mutation Res 2005; 569:29-63; PMID:15603751; http://dx.doi.org/10.1016/j.mrfmmm.2004.06.056
-
(2005)
Mutation Res
, vol.569
, pp. 29-63
-
-
Schroder, M.1
Kaufman, R.J.2
-
4
-
-
34247113888
-
Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: Ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II)
-
Fujita E, Kouroku Y, Isoai A, Kumagai H, Misutani A, Matsuda C, Hayashi YK, Momoi T. Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II). Hum Mol Genet 2007; 16:618-29; http://dx.doi.org/10.1093/hmg/ddm002
-
(2007)
Hum Mol Genet
, vol.16
, pp. 618-629
-
-
Fujita, E.1
Kouroku, Y.2
Isoai, A.3
Kumagai, H.4
Misutani, A.5
Matsuda, C.6
Hayashi, Y.K.7
Momoi, T.8
-
5
-
-
84897986050
-
Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHR
-
PMID:24685158
-
Houck SA, Ren HY, Madden VJ, Bonner JN, Conlin MP, Janovick JA, Conn PM, Cyr DM. Quality control autophagy degrades soluble ERAD-resistant conformers of the misfolded membrane protein GnRHR. Mol Cell 2014; 54:166-79; PMID:24685158; http://dx.doi.org/10.1016/j.molcel.2014.02.025
-
(2014)
Mol Cell
, vol.54
, pp. 166-179
-
-
Houck, S.A.1
Ren, H.Y.2
Madden, V.J.3
Bonner, J.N.4
Conlin, M.P.5
Janovick, J.A.6
Conn, P.M.7
Cyr, D.M.8
-
6
-
-
33846548110
-
ER stress and diseases
-
PMID:17288551
-
Yoshida H. ER stress and diseases. FEBS J 2007; 274:630-58; PMID:17288551; http://dx.doi.org/10.1111/j.1742-4658.2007.05639.x
-
(2007)
FEBS J
, vol.274
, pp. 630-658
-
-
Yoshida, H.1
-
7
-
-
33645156429
-
From acute ER stress to physiological roles of the Unfolded Protein Response
-
PMID:16397578
-
Wu J, Kaufman RJ. From acute ER stress to physiological roles of the Unfolded Protein Response. Cell Death Differ 2006; 13:374-84; PMID:16397578; http://dx.doi.org/10.1038/sj.cdd.4401840
-
(2006)
Cell Death Differ
, vol.13
, pp. 374-384
-
-
Wu, J.1
Kaufman, R.J.2
-
8
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
PMID:10854322
-
Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol 2000; 2:326-32; PMID:10854322; http://dx.doi.org/10.1038/35014014
-
(2000)
Nat Cell Biol
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
9
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
PMID:17565364
-
Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007; 8:519-29; PMID:17565364; http://dx.doi.org/10.1038/nrm2199
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
10
-
-
34249707984
-
Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1
-
PMID:17452628
-
Oikawa D, Kimata Y, Kohno K. Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1. J Cell Sci 2007; 120:1681-8; PMID:17452628; http://dx.doi.org/10.1242/jcs.002808
-
(2007)
J Cell Sci
, vol.120
, pp. 1681-1688
-
-
Oikawa, D.1
Kimata, Y.2
Kohno, K.3
-
11
-
-
33749233991
-
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
-
PMID:16973740
-
Zhou J, Liu CY, Back SH, Clark RL, Peisach D, Xu Z, Kaufman RJ. The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response. Proc Natl Acad Sci USA 2006; 103:14343-8; PMID:16973740; http://dx.doi.org/10.1073/pnas.0606480103
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14343-14348
-
-
Zhou, J.1
Liu, C.Y.2
Back, S.H.3
Clark, R.L.4
Peisach, D.5
Xu, Z.6
Kaufman, R.J.7
-
12
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
PMID:11779464
-
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K. XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 2001; 107:881-91; PMID:11779464; http://dx.doi.org/10.1016/S0092-8674(01)00611-0
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
-
13
-
-
0037083755
-
IRE1-mediated unconventional mRNA splicing and S2Pmediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
-
PMID:11850408
-
Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ. IRE1-mediated unconventional mRNA splicing and S2Pmediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 2002; 16:452-66; PMID:11850408; http://dx.doi. org/10.1101/gad.964702
-
(2002)
Genes Dev
, vol.16
, pp. 452-466
-
-
Lee, K.1
Tirasophon, W.2
Shen, X.3
Michalak, M.4
Prywes, R.5
Okada, T.6
Yoshida, H.7
Mori, K.8
Kaufman, R.J.9
-
14
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
PMID:10650002
-
Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP, Ron D. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 2000; 287:664-6; PMID:10650002; http://dx.doi.org/10.1126/science.287.5453.664
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
Zhang, Y.4
Chung, P.5
Harding, H.P.6
Ron, D.7
-
15
-
-
30944458057
-
Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK
-
PMID:16418533
-
Marciniak SJ, Garcia-Bonilla L, Hu J, Harding HP, Ron D. Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK. J Cell Biol 2006; 172:201-9; PMID:16418533; http://dx. doi.org/10.1083/jcb.200508099
-
(2006)
J Cell Biol
, vol.172
, pp. 201-209
-
-
Marciniak, S.J.1
Garcia-Bonilla, L.2
Hu, J.3
Harding, H.P.4
Ron, D.5
-
16
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
PMID:14517290
-
Cullinan SB, Zhang D, Hannink M, Arvisais E, Kaufman RJ, Diehl JA. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol 2003; 23:7198-209; PMID:14517290; http://dx.doi.org/10.1128/MCB.23.20.7198-7209. 2003
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
17
-
-
0036069980
-
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals
-
PMID:12110171
-
Shen J, Chen X, Hendershot L, Prywes R. ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev Cell 2002; 3:99-111; PMID:12110171; http://dx.doi.org/10.1016/S1534-5807(02)00203-4
-
(2002)
Dev Cell
, vol.3
, pp. 99-111
-
-
Shen, J.1
Chen, X.2
Hendershot, L.3
Prywes, R.4
-
18
-
-
33748789479
-
Mediators of endoplasmic reticulum stress-induced apoptosis
-
PMID:16953201
-
Szegezdi E, Logue SE, Gorman AM, Samali A. Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 2006; 7:880-5; PMID:16953201; http://dx.doi.org/10.1038/sj.embor.7400779
-
(2006)
EMBO Rep
, vol.7
, pp. 880-885
-
-
Szegezdi, E.1
Logue, S.E.2
Gorman, A.M.3
Samali, A.4
-
19
-
-
33751069967
-
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
-
PMID:17090218
-
Rutkowski DT, Arnold SM, Miller CN, Wu J, Li J, Gunnison KM, Mori K, Sadighi Akha AA, Raden D, Kaufman RJ. Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol 2006; 4:e374; PMID:17090218; http://dx.doi.org/10.1371/journal. pbio.0040374
-
(2006)
PLoS Biol
, vol.4
-
-
Rutkowski, D.T.1
Arnold, S.M.2
Miller, C.N.3
Wu, J.4
Li, J.5
Gunnison, K.M.6
Mori, K.7
Sadighi Akha, A.A.8
Raden, D.9
Kaufman, R.J.10
-
20
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
PMID:16825573
-
Hollien J, Weissman JS. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 2006; 313:104-7; PMID:16825573; http://dx.doi.org/10.1126/science.1129631
-
(2006)
Science
, vol.313
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
21
-
-
59649092854
-
Messenger RNA targeting to endoplasmic reticulum stress signalling sites
-
PMID:19079237
-
Aragon T, van Anken E, Pincus D, Serafimova IM, Korennykh AV, Rubio CA, Walter P. Messenger RNA targeting to endoplasmic reticulum stress signalling sites. Nature 2009; 457:736-40; PMID:19079237; http://dx.doi.org/10.1038/nature07641
-
(2009)
Nature
, vol.457
, pp. 736-740
-
-
Aragon, T.1
van Anken, E.2
Pincus, D.3
Serafimova, I.M.4
Korennykh, A.V.5
Rubio, C.A.6
Walter, P.7
-
22
-
-
84867038186
-
Silencing of lipid metabolism genes through IRE1alpha-mediated mRNA decay lowers plasma lipids in mice
-
PMID:23040070
-
So JS, Hur KY, Tarrio M, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Lichtman AH, Iwawaki T, Glimcher LH, et al. Silencing of lipid metabolism genes through IRE1alpha-mediated mRNA decay lowers plasma lipids in mice. Cell Metab 2012; 16:487-99; PMID:23040070; http://dx. doi.org/10.1016/j.cmet.2012.09.004
-
(2012)
Cell Metab
, vol.16
, pp. 487-499
-
-
So, J.S.1
Hur, K.Y.2
Tarrio, M.3
Ruda, V.4
Frank-Kamenetsky, M.5
Fitzgerald, K.6
Koteliansky, V.7
Lichtman, A.H.8
Iwawaki, T.9
Glimcher, L.H.10
-
23
-
-
79958033194
-
Modulating stress responses by the UPRosome: A matter of life and death
-
PMID:21482118
-
Woehlbier U, Hetz C. Modulating stress responses by the UPRosome: a matter of life and death. Trends Biochemical Sci 2011; 36:329-37; PMID:21482118; http://dx.doi.org/10.1016/j.tibs.2011.03.001
-
(2011)
Trends Biochemical Sci
, vol.36
, pp. 329-337
-
-
Woehlbier, U.1
Hetz, C.2
-
24
-
-
0030053047
-
Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention
-
PMID:8647884
-
Pahl HL, Sester M, Burgert HG, Baeuerle PA. Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention. J Cell Biol 1996; 132:511-22; PMID:8647884; http://dx. doi.org/10.1083/jcb.132.4.511
-
(1996)
J Cell Biol
, vol.132
, pp. 511-522
-
-
Pahl, H.L.1
Sester, M.2
Burgert, H.G.3
Baeuerle, P.A.4
-
25
-
-
84868130018
-
ER stress activates NF-kappaB by integrating functions of basal IKK activity, IRE1 and PERK
-
PMID:23110043
-
Tam AB, Mercado EL, Hoffmann A, Niwa M. ER stress activates NF-kappaB by integrating functions of basal IKK activity, IRE1 and PERK. PloS One 2012; 7:e45078; PMID:23110043; http://dx.doi.org/10.1371/journal.pone.0045078
-
(2012)
PloS One
, vol.7
-
-
Tam, A.B.1
Mercado, E.L.2
Hoffmann, A.3
Niwa, M.4
-
26
-
-
36049049392
-
IRE1 signaling affects cell fate during the unfolded protein response
-
PMID:17991856
-
Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, Panning B, Shokat KM, Lavail MM, Walter P. IRE1 signaling affects cell fate during the unfolded protein response. Science 2007; 318:944-9; PMID:17991856; http://dx.doi.org/10.1126/science. 1146361
-
(2007)
Science
, vol.318
, pp. 944-949
-
-
Lin, J.H.1
Li, H.2
Yasumura, D.3
Cohen, H.R.4
Zhang, C.5
Panning, B.6
Shokat, K.M.7
Lavail, M.M.8
Walter, P.9
-
27
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
PMID:14685163
-
Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004; 11:381-9; PMID:14685163; http://dx.doi.org/10.1038/sj.cdd.4401373
-
(2004)
Cell Death Differ
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
28
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
PMID:12667446
-
Harding HP, Zhang Y, Zeng H, Novoa I, Lu PD, Calfon M, Sadri N, Yun C, Popko B, Paules R, et al. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 2003; 11:619-33; PMID:12667446; http://dx. doi.org/10.1016/S1097-2765(03)00105-9
-
(2003)
Mol Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
-
29
-
-
0034973982
-
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
-
PMID:11430820
-
Scheuner D, Song B, McEwen E, Liu C, Laybutt R, Gillespie P, Saunders T, Bonner-Weir S, Kaufman RJ. Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell 2001; 7:1165-76; PMID:11430820; http://dx. doi.org/10.1016/S1097-2765(01)00265-9
-
(2001)
Mol Cell
, vol.7
, pp. 1165-1176
-
-
Scheuner, D.1
Song, B.2
McEwen, E.3
Liu, C.4
Laybutt, R.5
Gillespie, P.6
Saunders, T.7
Bonner-Weir, S.8
Kaufman, R.J.9
-
30
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
PMID:15601821
-
Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R, Nagata K, Harding HP, Ron D. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 2004; 18:3066-77; PMID:15601821; http://dx.doi.org/10.1101/gad.1250704
-
(2004)
Genes Dev
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
Nagata, K.7
Harding, H.P.8
Ron, D.9
-
31
-
-
70349777048
-
Regulation of apoptosis by the unfolded protein response
-
PMID:19609758
-
Fribley A, Zhang K, Kaufman RJ. Regulation of apoptosis by the unfolded protein response. Methods Mol Biol 2009; 559:191-204; PMID:19609758; http://dx.doi.org/10.1007/978-1-60327-017-5_14
-
(2009)
Methods Mol Biol
, vol.559
, pp. 191-204
-
-
Fribley, A.1
Zhang, K.2
Kaufman, R.J.3
-
32
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
PMID:11057897
-
Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000; 103:239-52; PMID:11057897; http://dx.doi.org/10.1016/S0092-8674(00)00116-1
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
33
-
-
0035879276
-
Stressinducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinasedependent and -independent mechanisms
-
PMID:11426938
-
Maytin EV, Ubeda M, Lin JC, Habener JF. Stressinducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinasedependent and -independent mechanisms. Exp Cell Res 2001; 267:193-204; PMID:11426938; http://dx. doi.org/10.1006/excr.2001.5248
-
(2001)
Exp Cell Res
, vol.267
, pp. 193-204
-
-
Maytin, E.V.1
Ubeda, M.2
Lin, J.C.3
Habener, J.F.4
-
34
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulumstress-induced apoptosis and Abeta-induced cell death
-
PMID:15123740
-
Hitomi J, Katayama T, Eguchi Y, Kudo T, Taniguchi M, Koyama Y, Manabe T, Yamagishi S, Bando Y, Imaizumi K, et al. Involvement of caspase-4 in endoplasmic reticulumstress-induced apoptosis and Abeta-induced cell death. J Cell Biol 2004; 165:347-56; PMID:15123740; http://dx.doi.org/10.1083/jcb.200310015
-
(2004)
J Cell Biol
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Koyama, Y.6
Manabe, T.7
Yamagishi, S.8
Bando, Y.9
Imaizumi, K.10
-
35
-
-
80053371703
-
Activation of ER stress and apoptosis by hydrogen peroxide in HeLa cells: Protective role of mild heat preconditioning at 40 ºC
-
PMID:21875624
-
Pallepati P, Averill-Bates DA. Activation of ER stress and apoptosis by hydrogen peroxide in HeLa cells: protective role of mild heat preconditioning at 40 ºC. Biochimica Et Biophysica Acta 2011; 1813:1987-99; PMID:21875624; http://dx.doi.org/10.1016/j.bbamcr.2011.07.021
-
(2011)
Biochimica Et Biophysica Acta
, vol.1813
, pp. 1987-1999
-
-
Pallepati, P.1
Averill-Bates, D.A.2
-
36
-
-
23844481790
-
Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis
-
PMID:15975932
-
Obeng EA, Boise LH. Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis. J Biol Chem 2005; 280:29578-87; PMID:15975932; http://dx.doi.org/10.1074/jbc.M502685200
-
(2005)
J Biol Chem
, vol.280
, pp. 29578-29587
-
-
Obeng, E.A.1
Boise, L.H.2
-
37
-
-
84899762669
-
Endoplasmic reticulum stressmediated activation of p38 MAPK, Caspase-2 and Caspase-8 leads to abrin-induced apoptosis
-
PMID:24664279
-
Mishra R, Karande AA. Endoplasmic reticulum stressmediated activation of p38 MAPK, Caspase-2 and Caspase-8 leads to abrin-induced apoptosis. PloS One 2014; 9:e92586; PMID:24664279; http://dx.doi.org/10.1371/journal.pone.0092586
-
(2014)
PloS One
, vol.9
-
-
Mishra, R.1
Karande, A.A.2
-
38
-
-
0036091476
-
The PERK eukaryotic initiation factor 2 a kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas
-
PMID:11997520
-
Zhang P, McGrath B, Li S, Frank A, Zambito F, Reinert J, Gannon M, Ma K, McNaughton K, Cavener DR. The PERK eukaryotic initiation factor 2 a kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas. Mol Cell Biol 2002; 22:3864-74; PMID:11997520; http://dx.doi.org/10.1128/MCB.22.11.3864-3874.2002
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3864-3874
-
-
Zhang, P.1
McGrath, B.2
Li, S.3
Frank, A.4
Zambito, F.5
Reinert, J.6
Gannon, M.7
Ma, K.8
McNaughton, K.9
Cavener, D.R.10
-
39
-
-
80052342419
-
PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment
-
PMID:21709020
-
Avivar-Valderas A, Salas E, Bobrovnikova-Marjon E, Diehl JA, Nagi C, Debnath J, Aguirre-Ghiso JA. PERK integrates autophagy and oxidative stress responses to promote survival during extracellular matrix detachment.Mol Cell Biol 2011; 31:3616-29; PMID:21709020; http://dx. doi.org/10.1128/MCB.05164-11
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3616-3629
-
-
Avivar-Valderas, A.1
Salas, E.2
Bobrovnikova-Marjon, E.3
Diehl, J.A.4
Nagi, C.5
Debnath, J.6
Aguirre-Ghiso, J.A.7
-
40
-
-
84908478414
-
Endoplasmic reticulum stress-mediated autophagy protects against lipopolysaccharide-induced apoptosis in HL-1 cardiomyocytes
-
PMID:24951501
-
Zou X, Xu J, Yao S, Li J, Yang Y, Yang L. Endoplasmic reticulum stress-mediated autophagy protects against lipopolysaccharide-induced apoptosis in HL-1 cardiomyocytes. Exp Physiol 2014; 99:1348-58; PMID:24951501; http://dx.doi.org/10.1113/expphysiol.2014.079012
-
(2014)
Exp Physiol
, vol.99
, pp. 1348-1358
-
-
Zou, X.1
Xu, J.2
Yao, S.3
Li, J.4
Yang, Y.5
Yang, L.6
-
41
-
-
0037039442
-
Regulation of starvation-and virus-induced autophagy by the eIF2alpha kinase signaling pathway
-
PMID:11756670
-
Talloczy Z, Jiang W, Virgin HW, 4th, Leib DA, Scheuner D, Kaufman RJ, Eskelinen EL, Levine B. Regulation of starvation-and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Proc Natl Acad Sci USA 2002; 99:190-5; PMID:11756670; http://dx.doi.org/10.1073/pnas.012485299
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 190-195
-
-
Talloczy, Z.1
Jiang, W.2
Virgin, H.W.3
Leib, D.A.4
Scheuner, D.5
Kaufman, R.J.6
Eskelinen, E.L.7
Levine, B.8
-
42
-
-
0032452122
-
Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres
-
Tanaka T, Tsujimura T, Takeda K, Sugihara A, Maekawa A, Terada N, Yoshida N, Akira S. Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres. Genes Cells 1998; 3:801-10; http://dx. doi.org/10.1046/j.1365-2443.1998.00230.x
-
(1998)
Genes Cells
, vol.3
, pp. 801-810
-
-
Tanaka, T.1
Tsujimura, T.2
Takeda, K.3
Sugihara, A.4
Maekawa, A.5
Terada, N.6
Yoshida, N.7
Akira, S.8
-
43
-
-
0034213391
-
Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor
-
PMID:10885750
-
Hettmann T, Barton K, Leiden JM. Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor. Dev Biol 2000; 222:110-23; PMID:10885750; http://dx.doi.org/10.1006/dbio.2000.9699
-
(2000)
Dev Biol
, vol.222
, pp. 110-123
-
-
Hettmann, T.1
Barton, K.2
Leiden, J.M.3
-
44
-
-
71449099881
-
Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription
-
PMID:19906842
-
Wang W, Lian N, Li L, Moss HE, Perrien DS, Elefteriou F, Yang X. Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development 2009; 136:4143-53; PMID:19906842; http://dx.doi.org/10.1242/dev.043281
-
(2009)
Development
, vol.136
, pp. 4143-4153
-
-
Wang, W.1
Lian, N.2
Li, L.3
Moss, H.E.4
Perrien, D.S.5
Elefteriou, F.6
Yang, X.7
-
45
-
-
70350539531
-
Atf4 regulates obesity, glucose homeostasis, and energy expenditure
-
PMID:19690063
-
Seo J, Fortuno ES, 3rd, Suh JM, Stenesen D, Tang W, Parks EJ, Adams CM, Townes T, Graff JM. Atf4 regulates obesity, glucose homeostasis, and energy expenditure. Diabetes 2009; 58:2565-73; PMID:19690063; http://dx.doi.org/10.2337/db09-0335
-
(2009)
Diabetes
, vol.58
, pp. 2565-2573
-
-
Seo, J.1
Fortuno, E.S.2
Suh, J.M.3
Stenesen, D.4
Tang, W.5
Parks, E.J.6
Adams, C.M.7
Townes, T.8
Graff, J.M.9
-
46
-
-
0036464604
-
Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice
-
PMID:11806972
-
Masuoka HC, Townes TM. Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice. Blood 2002; 99:736-45; PMID:11806972; http://dx.doi.org/10.1182/blood. V99.3.736
-
(2002)
Blood
, vol.99
, pp. 736-745
-
-
Masuoka, H.C.1
Townes, T.M.2
-
47
-
-
77956232915
-
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress
-
PMID:20631254
-
Yamamoto K, Takahara K, Oyadomari S, Okada T, Sato T, Harada A, Mori K. Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress. Mol Biol Cell 2010; 21:2975-86; PMID:20631254; http://dx.doi.org/10.1091/mbc. E09-02-0133
-
(2010)
Mol Biol Cell
, vol.21
, pp. 2975-2986
-
-
Yamamoto, K.1
Takahara, K.2
Oyadomari, S.3
Okada, T.4
Sato, T.5
Harada, A.6
Mori, K.7
-
48
-
-
34548172495
-
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1
-
PMID:17765680
-
Yamamoto K, Sato T, Matsui T, Sato M, Okada T, Yoshida H, Harada A, Mori K. Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Dev Cell 2007; 13:365-76; PMID:17765680; http://dx.doi.org/10.1016/j. devcel.2007.07.018
-
(2007)
Dev Cell
, vol.13
, pp. 365-376
-
-
Yamamoto, K.1
Sato, T.2
Matsui, T.3
Sato, M.4
Okada, T.5
Yoshida, H.6
Harada, A.7
Mori, K.8
-
49
-
-
84907856144
-
Regulation of the deathassociated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1
-
PMID:25135476
-
Gade P, Manjegowda SB, Nallar SC, Maachani UB, Cross AS, Kalvakolanu DV. Regulation of the deathassociated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1. Mol Cell Biol 2014; 34:4033-48; PMID:25135476; http://dx.doi.org/10.1128/MCB.00397-14
-
(2014)
Mol Cell Biol
, vol.34
, pp. 4033-4048
-
-
Gade, P.1
Manjegowda, S.B.2
Nallar, S.C.3
Maachani, U.B.4
Cross, A.S.5
Kalvakolanu, D.V.6
-
50
-
-
70349756962
-
Function of IRE1 a in the placenta is essential for placental development and embryonic viability
-
PMID:19805353
-
Iwawaki T, Akai R, Yamanaka S, Kohno K. Function of IRE1 a in the placenta is essential for placental development and embryonic viability. Proc Natl Acad Sci USA 2009; 106:16657-62; PMID:19805353; http://dx.doi.org/10.1073/pnas.0903775106
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16657-16662
-
-
Iwawaki, T.1
Akai, R.2
Yamanaka, S.3
Kohno, K.4
-
51
-
-
14944371187
-
The unfolded protein response sensor IRE1-alpha is required at 2 distinct steps in B cell lymphopoiesis
-
PMID:15690081
-
Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ. The unfolded protein response sensor IRE1-alpha is required at 2 distinct steps in B cell lymphopoiesis. J Clin Invest 2005; 115:268-81; PMID:15690081; http://dx.doi.org/10.1172/JCI200521848
-
(2005)
J Clin Invest
, vol.115
, pp. 268-281
-
-
Zhang, K.1
Wong, H.N.2
Song, B.3
Miller, C.N.4
Scheuner, D.5
Kaufman, R.J.6
-
52
-
-
0034650851
-
An essential role in liver development for transcription factor XBP-1
-
PMID:10652269
-
Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, Zhang J, Horton HF, Scott A, Orkin SH, Byrne MC, et al. An essential role in liver development for transcription factor XBP-1. Genes Dev 2000; 14:152-7; PMID:10652269
-
(2000)
Genes Dev
, vol.14
, pp. 152-157
-
-
Reimold, A.M.1
Etkin, A.2
Clauss, I.3
Perkins, A.4
Friend, D.S.5
Zhang, J.6
Horton, H.F.7
Scott, A.8
Orkin, S.H.9
Byrne, M.C.10
-
53
-
-
29244448729
-
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands
-
PMID:16362047
-
Lee AH, Chu GC, Iwakoshi NN, Glimcher LH. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J 2005; 24:4368-80; PMID:16362047; http://dx.doi.org/10.1038/sj.emboj.7600903
-
(2005)
EMBO J
, vol.24
, pp. 4368-4380
-
-
Lee, A.H.1
Chu, G.C.2
Iwakoshi, N.N.3
Glimcher, L.H.4
-
54
-
-
84872311621
-
XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation
-
PMID:23184933
-
Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S, Karamariti E, Xiao Q, Zampetaki A, Zhang Z, et al. XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation. J Biol Chem 2013; 288:859-72; PMID:23184933; http://dx.doi. org/10.1074/jbc.M112.412783
-
(2013)
J Biol Chem
, vol.288
, pp. 859-872
-
-
Margariti, A.1
Li, H.2
Chen, T.3
Martin, D.4
Vizcay-Barrena, G.5
Alam, S.6
Karamariti, E.7
Xiao, Q.8
Zampetaki, A.9
Zhang, Z.10
-
55
-
-
0013865801
-
Functions of lysosomes
-
PMID:5322983
-
De Duve C, Wattiaux R. Functions of lysosomes. Ann Rev Physiol 1966; 28:435-92; PMID:5322983; http://dx.doi.org/10.1146/annurev.ph.28.030166.002251
-
(1966)
Ann Rev Physiol
, vol.28
, pp. 435-492
-
-
De Duve, C.1
Wattiaux, R.2
-
56
-
-
84867246279
-
Autophagy: Mechanism and physiological relevance 'brewed' from yeast studies
-
PMID:22652877
-
Devenish RJ, Klionsky DJ. Autophagy: mechanism and physiological relevance 'brewed' from yeast studies. Front Biosci (Schol Ed) 2012; 4:1354-63; PMID:22652877; http://dx.doi.org/10.2741/S337
-
(2012)
Front Biosci (Schol Ed)
, vol.4
, pp. 1354-1363
-
-
Devenish, R.J.1
Klionsky, D.J.2
-
57
-
-
10744225487
-
A unified nomenclature for yeast autophagy-related genes
-
PMID:14536056
-
Klionsky DJ, Cregg JM, Dunn WA, Jr, Emr SD, Sakai Y, Sandoval IV, Sibirny A, Subramani S, Thumm M, Veenhuis M, et al. A unified nomenclature for yeast autophagy-related genes. Dev Cell 2003; 5:539-45; PMID:14536056; http://dx.doi.org/10.1016/S1534-5807(03)00296-X
-
(2003)
Dev Cell
, vol.5
, pp. 539-545
-
-
Klionsky, D.J.1
Cregg, J.M.2
Dunn, W.A.3
Emr, S.D.4
Sakai, Y.5
Sandoval, I.V.6
Sibirny, A.7
Subramani, S.8
Thumm, M.9
Veenhuis, M.10
-
58
-
-
84858304558
-
The Cytoplasm-to-Vacuole Targeting Pathway: A Historical Perspective
-
PMID:22481942
-
Umekawa M, Klionsky DJ. The Cytoplasm-to-Vacuole Targeting Pathway: A Historical Perspective. Int J Cell Biol 2012; 2012:142634; PMID:22481942; http://dx.doi.org/10.1155/2012/142634
-
(2012)
Int J Cell Biol
, vol.2012
-
-
Umekawa, M.1
Klionsky, D.J.2
-
59
-
-
34147141497
-
Switch between apoptosis and autophagy: Radiation-induced endoplasmic reticulum stress?
-
PMID:17377498
-
Moretti L, Cha YI, Niermann KJ, Lu B. Switch between apoptosis and autophagy: radiation-induced endoplasmic reticulum stress? Cell Cycle 2007; 6:793-8; PMID:17377498; http://dx.doi.org/10.4161/cc.6.7.4036
-
(2007)
Cell Cycle
, vol.6
, pp. 793-798
-
-
Moretti, L.1
Cha, Y.I.2
Niermann, K.J.3
Lu, B.4
-
60
-
-
84923285482
-
Lysosome: Regulator of lipid degradation pathways
-
PMID:25061009
-
Settembre C, Ballabio A. Lysosome: regulator of lipid degradation pathways. Trends Cell Biol 2014; 24:743-50; PMID:25061009; http://dx.doi.org/10.1016/j.tcb.2014.06.006
-
(2014)
Trends Cell Biol
, vol.24
, pp. 743-750
-
-
Settembre, C.1
Ballabio, A.2
-
61
-
-
77956404377
-
Eaten alive: A history of macroautophagy
-
PMID:20811353
-
Yang Z, Klionsky DJ. Eaten alive: a history of macroautophagy. Nat Cell Biol 2010; 12:814-22; PMID:20811353; http://dx.doi.org/10.1038/ncb0910-814
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
62
-
-
34250864795
-
Protein turnover via autophagy: Implications for metabolism
-
PMID:17311494
-
Mizushima N, Klionsky DJ. Protein turnover via autophagy: implications for metabolism. Annu Rev Nutri 2007; 27:19-40; PMID:17311494; http://dx. doi.org/10.1146/annurev.nutr.27.061406.093749
-
(2007)
Annu Rev Nutri
, vol.27
, pp. 19-40
-
-
Mizushima, N.1
Klionsky, D.J.2
-
63
-
-
46849115787
-
Autophagy is essential for preimplantation development of mouse embryos
-
PMID:18599786
-
Tsukamoto S, Kuma A, Murakami M, Kishi C, Yamamoto A, Mizushima N. Autophagy is essential for preimplantation development of mouse embryos. Science 2008; 321:117-20; PMID:18599786; http://dx.doi.org/10.1126/science.1154822
-
(2008)
Science
, vol.321
, pp. 117-120
-
-
Tsukamoto, S.1
Kuma, A.2
Murakami, M.3
Kishi, C.4
Yamamoto, A.5
Mizushima, N.6
-
64
-
-
82255183165
-
Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission
-
PMID:22033522
-
Al Rawi S, Louvet-Vallee S, Djeddi A, Sachse M, Culetto E, Hajjar C, Boyd L, Legouis R, Galy V. Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission. Science 2011; 334:1144-7; PMID:22033522http://dx.doi. org/10.1126/science.1211878
-
(2011)
Science
, vol.334
, pp. 1144-1147
-
-
Al Rawi, S.1
Louvet-Vallee, S.2
Djeddi, A.3
Sachse, M.4
Culetto, E.5
Hajjar, C.6
Boyd, L.7
Legouis, R.8
Galy, V.9
-
65
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
PMID:15525940
-
Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, Ohsumi Y, Tokuhisa T, Mizushima N. The role of autophagy during the early neonatal starvation period. Nature 2004; 432:1032-6; PMID:15525940; http://dx.doi.org/10.1038/nature03029
-
(2004)
Nature
, vol.432
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
Yamamoto, A.4
Nakaya, H.5
Yoshimori, T.6
Ohsumi, Y.7
Tokuhisa, T.8
Mizushima, N.9
-
66
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
PMID:18305538
-
Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451:1069-75; PMID:18305538; http://dx.doi.org/10.1038/nature06639
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
67
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signaling regulation
-
PMID:20034776
-
Yang Z, Klionsky DJ. Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol 2010; 22:124-31; PMID:20034776; http://dx.doi.org/10.1016/j.ceb.2009.11.014
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
68
-
-
77956416339
-
Autophagy in mammalian development and differentiation
-
PMID:20811354
-
Mizushima N, Levine B. Autophagy in mammalian development and differentiation. Nat Cell Biol 2010; 12:823-30; PMID:20811354; http://dx.doi.org/10.1038/ncb0910-823
-
(2010)
Nat Cell Biol
, vol.12
, pp. 823-830
-
-
Mizushima, N.1
Levine, B.2
-
69
-
-
84864318195
-
Chaperone-mediated autophagy: A unique way to enter the lysosome world
-
PMID:22748206
-
Kaushik S, Cuervo AM. Chaperone-mediated autophagy: a unique way to enter the lysosome world. Trends Cell Biol 2012; 22:407-17; PMID:22748206; http://dx.doi.org/10.1016/j.tcb.2012.05.006
-
(2012)
Trends Cell Biol
, vol.22
, pp. 407-417
-
-
Kaushik, S.1
Cuervo, A.M.2
-
70
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
PMID:19653858
-
He C, Klionsky DJ. Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 2009; 43:67-93; PMID:19653858; http://dx.doi.org/10.1146/annurev-genet-102808-114910
-
(2009)
Annu Rev Genet
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
71
-
-
77950994646
-
Autophagy: Cellular and molecular mechanisms
-
PMID:20225336
-
Glick D, Barth S, Macleod KF. Autophagy: cellular and molecular mechanisms. J Pathol 2010; 221:3-12; PMID:20225336; http://dx.doi.org/10.1002/path.2697
-
(2010)
J Pathol
, vol.221
, pp. 3-12
-
-
Glick, D.1
Barth, S.2
Macleod, K.F.3
-
72
-
-
0038309329
-
The molecular mechanism of autophagy
-
PMID:12865942
-
Wang CW, Klionsky DJ. The molecular mechanism of autophagy. Mol Med 2003; 9:65-76; PMID:12865942
-
(2003)
Mol Med
, vol.9
, pp. 65-76
-
-
Wang, C.W.1
Klionsky, D.J.2
-
73
-
-
84855500993
-
Autophagy: For better or for worse
-
PMID:21912435
-
Wirawan E, Vanden Berghe T, Lippens S, Agostinis P, Vandenabeele P. Autophagy: for better or for worse. Cell Res 2012; 22:43-61; PMID:21912435; http://dx.doi.org/10.1038/cr.2011.152
-
(2012)
Cell Res
, vol.22
, pp. 43-61
-
-
Wirawan, E.1
Vanden Berghe, T.2
Lippens, S.3
Agostinis, P.4
Vandenabeele, P.5
-
74
-
-
67549110195
-
A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy
-
PMID:19287211
-
Mercer CA, Kaliappan A, Dennis PB. A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy. Autophagy 2009; 5:649-62; PMID:19287211; http://dx.doi.org/10.4161/auto.5.5.8249
-
(2009)
Autophagy
, vol.5
, pp. 649-662
-
-
Mercer, C.A.1
Kaliappan, A.2
Dennis, P.B.3
-
75
-
-
84865805718
-
Two hits are better than one: Targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment
-
PMID:22564882
-
Martelli AM, Chiarini F, Evangelisti C, Cappellini A, Buontempo F, Bressanin D, Fini M, McCubrey JA. Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment. Oncotarget 2012; 3:371-94; PMID:22564882; http://dx.doi.org/10.18632/oncotarget.477
-
(2012)
Oncotarget
, vol.3
, pp. 371-394
-
-
Martelli, A.M.1
Chiarini, F.2
Evangelisti, C.3
Cappellini, A.4
Buontempo, F.5
Bressanin, D.6
Fini, M.7
McCubrey, J.A.8
-
76
-
-
70349919804
-
Coordination ofmembrane events during autophagy by multiple class III PI3-kinase complexes
-
PMID:19797076
-
Simonsen A, Tooze SA.Coordination ofmembrane events during autophagy by multiple class III PI3-kinase complexes. J Cell Biol 2009; 186:773-82; PMID:19797076; http://dx.doi.org/10.1083/jcb.200907014
-
(2009)
J Cell Biol
, vol.186
, pp. 773-782
-
-
Simonsen, A.1
Tooze, S.A.2
-
77
-
-
78650936005
-
The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression
-
PMID:21062745
-
Sun Q, Zhang J, Fan W, Wong KN, Ding X, Chen S, Zhong Q. The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression. J Biol Chem 2011; 286:185-91; PMID:21062745; http://dx.doi.org/10.1074/jbc. M110.126425
-
(2011)
J Biol Chem
, vol.286
, pp. 185-191
-
-
Sun, Q.1
Zhang, J.2
Fan, W.3
Wong, K.N.4
Ding, X.5
Chen, S.6
Zhong, Q.7
-
78
-
-
0001488499
-
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
-
PMID:9765397
-
Liang XH, Kleeman LK, Jiang HH, Gordon G, Goldman JE, Berry G, Herman B, Levine B. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol 1998; 72:8586-96; PMID:9765397
-
(1998)
J Virol
, vol.72
, pp. 8586-8596
-
-
Liang, X.H.1
Kleeman, L.K.2
Jiang, H.H.3
Gordon, G.4
Goldman, J.E.5
Berry, G.6
Herman, B.7
Levine, B.8
-
79
-
-
14044277429
-
The molecular machinery of autophagy: Unanswered questions
-
PMID:15615779
-
Klionsky DJ. The molecular machinery of autophagy: unanswered questions. J Cell Sci 2005; 118:7-18; PMID:15615779; http://dx.doi.org/10.1242/jcs.01620
-
(2005)
J Cell Sci
, vol.118
, pp. 7-18
-
-
Klionsky, D.J.1
-
80
-
-
0035286734
-
Molecular dissection of autophagy: Two ubiquitin-like systems
-
PMID:11265251
-
Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2001; 2:211-6; PMID:11265251; http://dx.doi.org/10.1038/35056522
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 211-216
-
-
Ohsumi, Y.1
-
81
-
-
0037401983
-
Role of the Apg12 conjugation system in mammalian autophagy
-
PMID:12672448
-
Mizushima N, Yoshimori T, Ohsumi Y. Role of the Apg12 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 2003; 35:553-61; PMID:12672448; http://dx.doi.org/10.1016/S1357-2725(02)00343-6
-
(2003)
Int J Biochem Cell Biol
, vol.35
, pp. 553-561
-
-
Mizushima, N.1
Yoshimori, T.2
Ohsumi, Y.3
-
82
-
-
38049098543
-
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy
-
PMID:17986448
-
Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y. The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem 2007; 282:37298-302; PMID:17986448; http://dx.doi.org/10.1074/jbc.C700195200
-
(2007)
J Biol Chem
, vol.282
, pp. 37298-37302
-
-
Hanada, T.1
Noda, N.N.2
Satomi, Y.3
Ichimura, Y.4
Fujioka, Y.5
Takao, T.6
Inagaki, F.7
Ohsumi, Y.8
-
83
-
-
34248203863
-
Structure of Atg5.Atg16, a complex essential for autophagy
-
PMID:17192262
-
Matsushita M, Suzuki NN, Obara K, Fujioka Y, Ohsumi Y, Inagaki F. Structure of Atg5.Atg16, a complex essential for autophagy. J Biol Chem 2007; 282:6763-72; PMID:17192262
-
(2007)
J Biol Chem
, vol.282
, pp. 6763-6772
-
-
Matsushita, M.1
Suzuki, N.N.2
Obara, K.3
Fujioka, Y.4
Ohsumi, Y.5
Inagaki, F.6
-
84
-
-
65649136884
-
The structure of Atg4BLC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy
-
PMID:19322194
-
Satoo K, Noda NN, Kumeta H, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F. The structure of Atg4BLC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. Embo J 2009; 28:1341-50; PMID:19322194; http://dx.doi.org/10.1038/emboj.2009.80
-
(2009)
Embo J
, vol.28
, pp. 1341-1350
-
-
Satoo, K.1
Noda, N.N.2
Kumeta, H.3
Fujioka, Y.4
Mizushima, N.5
Ohsumi, Y.6
Inagaki, F.7
-
85
-
-
4344624322
-
LC3 conjugation system in mammalian autophagy
-
PMID:15325588
-
Tanida I, Ueno T, Kominami E. LC3 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 2004; 36:2503-18; PMID:15325588; http://dx. doi.org/10.1016/j.biocel.2004.05.009
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2503-2518
-
-
Tanida, I.1
Ueno, T.2
Kominami, E.3
-
86
-
-
77951221542
-
The role of the Atg1/ULK1 complex in autophagy regulation
-
PMID:20056399
-
Mizushima N. The role of the Atg1/ULK1 complex in autophagy regulation. Curr Opin Cell Biol 2010; 22:132-9; PMID:20056399; http://dx.doi.org/10.1016/j.ceb.2009.12.004
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 132-139
-
-
Mizushima, N.1
-
87
-
-
47149089713
-
Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes
-
PMID:18388399
-
Kimura S, Noda T, Yoshimori T. Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes. Cell Struct Funct 2008; 33:109-22; PMID:18388399; http://dx.doi.org/10.1247/csf.08005
-
(2008)
Cell Struct Funct
, vol.33
, pp. 109-122
-
-
Kimura, S.1
Noda, T.2
Yoshimori, T.3
-
88
-
-
76149086512
-
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
-
PMID:20100911
-
Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T. FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. J Cell Biol 2010; 188:253-69; PMID:20100911; http://dx. doi.org/10.1083/jcb.200907015
-
(2010)
J Cell Biol
, vol.188
, pp. 253-269
-
-
Pankiv, S.1
Alemu, E.A.2
Brech, A.3
Bruun, J.A.4
Lamark, T.5
Overvatn, A.6
Bjørkøy, G.7
Johansen, T.8
-
89
-
-
7244255989
-
Role for Rab7 in maturation of late autophagic vacuoles
-
PMID:15340014
-
Jager S, Bucci C, Tanida I, Ueno T, Kominami E, Saftig P, Eskelinen EL. Role for Rab7 in maturation of late autophagic vacuoles. J Cell Sci 2004; 117:4837-48; PMID:15340014; http://dx.doi.org/10.1242/jcs.01370
-
(2004)
J Cell Sci
, vol.117
, pp. 4837-4848
-
-
Jager, S.1
Bucci, C.2
Tanida, I.3
Ueno, T.4
Kominami, E.5
Saftig, P.6
Eskelinen, E.L.7
-
90
-
-
79959415069
-
Biogenesis and cargo selectivity of autophagosomes
-
PMID:21548784
-
Weidberg H, Shvets E, Elazar Z. Biogenesis and cargo selectivity of autophagosomes. Annu Rev Biochem 2011; 80:125-56; PMID:21548784; http://dx.doi. org/10.1146/annurev-biochem-052709-094552
-
(2011)
Annu Rev Biochem
, vol.80
, pp. 125-156
-
-
Weidberg, H.1
Shvets, E.2
Elazar, Z.3
-
91
-
-
46449120732
-
Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
-
PMID:18552835
-
Liang C, Lee JS, Inn KS, Gack MU, Li Q, Roberts EA, Vergne I, Deretic V, Feng P, Akazawa C, et al. Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking. Nature Cell Biol 2008; 10:776-87; PMID:18552835; http://dx.doi.org/10.1038/ncb1740
-
(2008)
Nature Cell Biol
, vol.10
, pp. 776-787
-
-
Liang, C.1
Lee, J.S.2
Inn, K.S.3
Gack, M.U.4
Li, Q.5
Roberts, E.A.6
Vergne, I.7
Deretic, V.8
Feng, P.9
Akazawa, C.10
-
92
-
-
84869034809
-
Reduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblasts
-
PMID:22949512
-
Tatti M, Motta M, Di Bartolomeo S, Scarpa S, Cianfanelli V, Cecconi F, Salvioli R. Reduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblasts. Hum Mol Genet 2012; 21:5159-73; PMID:22949512; http://dx.doi.org/10.1093/hmg/dds367
-
(2012)
Hum Mol Genet
, vol.21
, pp. 5159-5173
-
-
Tatti, M.1
Motta, M.2
Di Bartolomeo, S.3
Scarpa, S.4
Cianfanelli, V.5
Cecconi, F.6
Salvioli, R.7
-
93
-
-
33845459165
-
Autophagy is activated for cell survival after endoplasmic reticulum stress
-
PMID:17030611
-
Ogata M, Hino S, Saito A, Morikawa K, Kondo S, Kanemoto S, Murakami T, Taniguchi M, Tanii I, Yoshinaga K, et al. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol 2006; 26:9220-31; PMID:17030611; http://dx. doi.org/10.1128/MCB.01453-06
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9220-9231
-
-
Ogata, M.1
Hino, S.2
Saito, A.3
Morikawa, K.4
Kondo, S.5
Kanemoto, S.6
Murakami, T.7
Taniguchi, M.8
Tanii, I.9
Yoshinaga, K.10
-
94
-
-
33845480131
-
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
-
PMID:17132049
-
Bernales S, McDonald KL, Walter P. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol 2006; 4:e423; PMID:17132049; http://dx.doi.org/10.1371/journal.pbio.0040423
-
(2006)
PLoS Biol
, vol.4
-
-
Bernales, S.1
McDonald, K.L.2
Walter, P.3
-
95
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
PMID:7481820
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270:1326-31; PMID:7481820; http://dx.doi.org/10.1126/science.270.5240.1326
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
96
-
-
84904980461
-
Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells
-
Cheng X, Liu H, Jiang CC, Fang L, Chen C, Zhang XD, Jiang ZW. Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells. Int J Mol Med 2014; 34:772-81
-
(2014)
Int J Mol Med
, vol.34
, pp. 772-781
-
-
Cheng, X.1
Liu, H.2
Jiang, C.C.3
Fang, L.4
Chen, C.5
Zhang, X.D.6
Jiang, Z.W.7
-
97
-
-
44949237240
-
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
-
PMID:18570871
-
Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008; 30:678-88; PMID:18570871; http://dx.doi.org/10.1016/j.molcel.2008.06.001
-
(2008)
Mol Cell
, vol.30
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
98
-
-
60149098492
-
The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells
-
PMID:19060920
-
Li DD, Wang LL, Deng R, Tang J, Shen Y, Guo JF, Wang Y, Xia LP, Feng GK, Liu QQ, et al. The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells. Oncogene 2009; 28:886-98; PMID:19060920; http://dx.doi.org/10.1038/onc.2008.441
-
(2009)
Oncogene
, vol.28
, pp. 886-898
-
-
Li, D.D.1
Wang, L.L.2
Deng, R.3
Tang, J.4
Shen, Y.5
Guo, J.F.6
Wang, Y.7
Xia, L.P.8
Feng, G.K.9
Liu, Q.Q.10
-
99
-
-
84878772042
-
Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response
-
PMID:24024137
-
Haberzettl P, Hill BG. Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response. Redox Biol 2013; 1:56-64; PMID:24024137; http://dx.doi. org/10.1016/j.redox.2012.10.003
-
(2013)
Redox Biol
, vol.1
, pp. 56-64
-
-
Haberzettl, P.1
Hill, B.G.2
-
100
-
-
34548299555
-
Linking of autophagy to ubiquitinproteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
-
PMID:17620365
-
Ding WX, Ni HM, Gao W, Yoshimori T, Stolz DB, Ron D, Yin XM. Linking of autophagy to ubiquitinproteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am J Pathol 2007; 171:513-24; PMID:17620365; http://dx.doi.org/10.2353/ajpath.2007.070188
-
(2007)
Am J Pathol
, vol.171
, pp. 513-524
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Yoshimori, T.4
Stolz, D.B.5
Ron, D.6
Yin, X.M.7
-
101
-
-
53549089861
-
Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation
-
PMID:18769111
-
Wei Y, Sinha S, Levine B. Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation. Autophagy 2008; 4:949-51; PMID:18769111; http://dx.doi.org/10.4161/auto.6788
-
(2008)
Autophagy
, vol.4
, pp. 949-951
-
-
Wei, Y.1
Sinha, S.2
Levine, B.3
-
102
-
-
84872036691
-
Structure of the human ATG12ÃTG5 conjugate required for LC3 lipidation in autophagy
-
PMID:23202584
-
Otomo C, Metlagel Z, Takaesu G, Otomo T. Structure of the human ATG12ÃTG5 conjugate required for LC3 lipidation in autophagy. Nat Struct Mol Biol 2013; 20:59-66; PMID:23202584; http://dx.doi.org/10.1038/nsmb.2431
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 59-66
-
-
Otomo, C.1
Metlagel, Z.2
Takaesu, G.3
Otomo, T.4
-
103
-
-
84885455062
-
The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression
-
PMID:23804767
-
B'Chir W, Maurin AC, Carraro V, Averous J, Jousse C, Muranishi Y, Parry L, Stepien G, Fafournoux P, Bruhat A. The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression. Nucleic Acids Res 2013; 41:7683-99; PMID:23804767; http://dx.doi.org/10.1093/nar/gkt563
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 7683-7699
-
-
B'Chir, W.1
Maurin, A.C.2
Carraro, V.3
Averous, J.4
Jousse, C.5
Muranishi, Y.6
Parry, L.7
Stepien, G.8
Fafournoux, P.9
Bruhat, A.10
-
104
-
-
33846211417
-
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
-
PMID:16794605
-
Kouroku Y, Fujita E, Tanida I, Ueno T, Isoai A, Kumagai H, Ogawa S, Kaufman RJ, Kominami E, Momoi T. ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. Cell Death Differ 2007; 14:230-9; PMID:16794605; http://dx.doi.org/10.1038/sj. cdd.4401984
-
(2007)
Cell Death Differ
, vol.14
, pp. 230-239
-
-
Kouroku, Y.1
Fujita, E.2
Tanida, I.3
Ueno, T.4
Isoai, A.5
Kumagai, H.6
Ogawa, S.7
Kaufman, R.J.8
Kominami, E.9
Momoi, T.10
-
105
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
PMID:20038797
-
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, et al. The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J Clin Invest 2010; 120:127-41; PMID:20038797; http://dx.doi.org/10.1172/JCI40027
-
(2010)
J Clin Invest
, vol.120
, pp. 127-141
-
-
Rouschop, K.M.1
van den Beucken, T.2
Dubois, L.3
Niessen, H.4
Bussink, J.5
Savelkouls, K.6
Keulers, T.7
Mujcic, H.8
Landuyt, W.9
Voncken, J.W.10
-
106
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
PMID:11158311
-
McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 2001; 21:1249-59; PMID:11158311; http://dx.doi.org/10.1128/MCB.21.4.1249-1259.2001
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
107
-
-
84870546460
-
ER stress-mediated autophagy promotes Mycdependent transformation and tumor growth
-
PMID:23143306
-
Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, et al. ER stress-mediated autophagy promotes Mycdependent transformation and tumor growth. J Clin Invest 2012; 122:4621-34; PMID:23143306; http://dx.doi.org/10.1172/JCI62973
-
(2012)
J Clin Invest
, vol.122
, pp. 4621-4634
-
-
Hart, L.S.1
Cunningham, J.T.2
Datta, T.3
Dey, S.4
Tameire, F.5
Lehman, S.L.6
Qiu, B.7
Zhang, H.8
Cerniglia, G.9
Bi, M.10
-
108
-
-
84959544375
-
Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 a kinase (eIF2alpha) pathway protect ovarian cancer cells from metformin-induced apoptosis
-
Forthcoming; PMID:25663310
-
Moon HS, Kim B, Gwak H, Suh DH, Song YS. Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 a kinase (eIF2alpha) pathway protect ovarian cancer cells from metformin-induced apoptosis. Mol Carcinog 2015; Forthcoming; PMID:25663310; http://dx. doi.org/10.1002/mc.22284
-
(2015)
Mol Carcinog
-
-
Moon, H.S.1
Kim, B.2
Gwak, H.3
Suh, D.H.4
Song, Y.S.5
-
109
-
-
84887999522
-
Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation
-
PMID:23916134
-
Bruning A, Rahmeh M, Friese K. Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation. Mol Oncol 2013; 7:1012-8; PMID:23916134; http://dx.doi.org/10.1016/j.molonc.2013.07.010
-
(2013)
Mol Oncol
, vol.7
, pp. 1012-1018
-
-
Bruning, A.1
Rahmeh, M.2
Friese, K.3
-
110
-
-
66249085237
-
The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib
-
PMID:19417138
-
Milani M, Rzymski T, Mellor HR, Pike L, Bottini A, Generali D, Harris AL. The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib. Cancer Res 2009; 69:4415-23; PMID:19417138; http://dx.doi.org/10.1158/0008-5472.CAN-08-2839
-
(2009)
Cancer Res
, vol.69
, pp. 4415-4423
-
-
Milani, M.1
Rzymski, T.2
Mellor, H.R.3
Pike, L.4
Bottini, A.5
Generali, D.6
Harris, A.L.7
-
111
-
-
64249134706
-
VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidification
-
PMID:19379691
-
Ramachandran N, Munteanu I, Wang P, Aubourg P, Rilstone JJ, Israelian N, Naranian T, Paroutis P, Guo R, Ren ZP, et al.VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidification. Cell 2009; 137:235-46; PMID:19379691; http://dx.doi.org/10.1016/j.cell.2009.01.054
-
(2009)
Cell
, vol.137
, pp. 235-246
-
-
Ramachandran, N.1
Munteanu, I.2
Wang, P.3
Aubourg, P.4
Rilstone, J.J.5
Israelian, N.6
Naranian, T.7
Paroutis, P.8
Guo, R.9
Ren, Z.P.10
-
112
-
-
65549101724
-
HspB8 participates in protein quality control by a non-chaperone-like mechanism that requires eIF2{a} phosphorylation
-
PMID:19114712
-
Carra S, Brunsting JF, Lambert H, Landry J, Kampinga HH. HspB8 participates in protein quality control by a non-chaperone-like mechanism that requires eIF2{a} phosphorylation. J Biol Chem 2009; 284:5523-32; PMID:19114712; http://dx.doi.org/10.1074/jbc.M807440200
-
(2009)
J Biol Chem
, vol.284
, pp. 5523-5532
-
-
Carra, S.1
Brunsting, J.F.2
Lambert, H.3
Landry, J.4
Kampinga, H.H.5
-
113
-
-
79952846029
-
Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent manner
-
Yung HW, Charnock-Jones DS, Burton GJ. Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent manner. PloS one 2011; 6:e17894;
-
(2011)
PloS one
, vol.6
-
-
Yung, H.W.1
Charnock-Jones, D.S.2
Burton, G.J.3
-
114
-
-
84869447873
-
IFNG and autophagy: A critical role for the ER-stress mediator ATF6 in controlling bacterial infections
-
PMID:22874566
-
Kalvakolanu DV, Gade P. IFNG and autophagy: a critical role for the ER-stress mediator ATF6 in controlling bacterial infections. Autophagy 2012; 8:1673-4; PMID:22874566; http://dx.doi.org/10.4161/auto.21403
-
(2012)
Autophagy
, vol.8
, pp. 1673-1674
-
-
Kalvakolanu, D.V.1
Gade, P.2
-
115
-
-
56349138968
-
DAPkinase is a mediator of endoplasmic reticulum stressinduced caspase activation and autophagic cell death
-
PMID:18806755
-
Gozuacik D, Bialik S, Raveh T, Mitou G, Shohat G, Sabanay H, Mizushima N, Yoshimori T, Kimchi A. DAPkinase is a mediator of endoplasmic reticulum stressinduced caspase activation and autophagic cell death. Cell Death Differ 2008; 15:1875-86; PMID:18806755; http://dx.doi.org/10.1038/cdd.2008.121
-
(2008)
Cell Death Differ
, vol.15
, pp. 1875-1886
-
-
Gozuacik, D.1
Bialik, S.2
Raveh, T.3
Mitou, G.4
Shohat, G.5
Sabanay, H.6
Mizushima, N.7
Yoshimori, T.8
Kimchi, A.9
-
116
-
-
61849102389
-
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy
-
PMID:19180116
-
Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R, Kimchi A. DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy. EMBO Rep 2009; 10:285-92; PMID:19180116; http://dx.doi.org/10.1038/embor.2008.246
-
(2009)
EMBO Rep
, vol.10
, pp. 285-292
-
-
Zalckvar, E.1
Berissi, H.2
Mizrachy, L.3
Idelchuk, Y.4
Koren, I.5
Eisenstein, M.6
Sabanay, H.7
Pinkas-Kramarski, R.8
Kimchi, A.9
-
117
-
-
77953139736
-
Fighting disease by selective autophagy of aggregate-prone proteins
-
PMID:20412801
-
Knaevelsrud H, Simonsen A. Fighting disease by selective autophagy of aggregate-prone proteins. FEBS Lett 2010; 584:2635-45; PMID:20412801; http://dx. doi.org/10.1016/j.febslet.2010.04.041
-
(2010)
FEBS Lett
, vol.584
, pp. 2635-2645
-
-
Knaevelsrud, H.1
Simonsen, A.2
-
118
-
-
77953506788
-
ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy
-
PMID:20104019
-
Qin L, Wang Z, Tao L, Wang Y. ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy. Autophagy 2010; 6:239-47; PMID:20104019; http://dx. doi.org/10.4161/auto.6.2.11062
-
(2010)
Autophagy
, vol.6
, pp. 239-247
-
-
Qin, L.1
Wang, Z.2
Tao, L.3
Wang, Y.4
-
119
-
-
10344253840
-
Critical role of endogenous Akt/IAPs andMEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
-
PMID:15339911
-
Hu P, Han Z, Couvillon AD, Exton JH. Critical role of endogenous Akt/IAPs andMEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J Biol Chem 2004; 279:49420-9; PMID:15339911; http://dx.doi.org/10.1074/jbc.M407700200
-
(2004)
J Biol Chem
, vol.279
, pp. 49420-49429
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Exton, J.H.4
-
120
-
-
69849109361
-
Activation of the Akt-NF-kappaB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response
-
PMID:19561103
-
Yamazaki H, Hiramatsu N, Hayakawa K, Tagawa Y, Okamura M, Ogata R, Huang T, Nakajima S, Yao J, Paton AW, et al. Activation of the Akt-NF-kappaB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response. J Immunol 2009; 183:1480-7; PMID:19561103; http://dx.doi. org/10.4049/jimmunol.0900017
-
(2009)
J Immunol
, vol.183
, pp. 1480-1487
-
-
Yamazaki, H.1
Hiramatsu, N.2
Hayakawa, K.3
Tagawa, Y.4
Okamura, M.5
Ogata, R.6
Huang, T.7
Nakajima, S.8
Yao, J.9
Paton, A.W.10
-
121
-
-
84876694384
-
AKT inhibition mitigates GRP78 (glucose-regulated protein) expression and contribution to chemoresistance in endometrial cancers
-
PMID:23280503
-
Gray MJ, Mhawech-Fauceglia P, Yoo E, Yang W, Wu E, Lee AS, Lin YG. AKT inhibition mitigates GRP78 (glucose-regulated protein) expression and contribution to chemoresistance in endometrial cancers. Int J Cancer 2013; 133:21-30; PMID:23280503; http://dx.doi.org/10.1002/ijc.27994
-
(2013)
Int J Cancer
, vol.133
, pp. 21-30
-
-
Gray, M.J.1
Mhawech-Fauceglia, P.2
Yoo, E.3
Yang, W.4
Wu, E.5
Lee, A.S.6
Lin, Y.G.7
-
122
-
-
84859962402
-
GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells
-
PMID:22529978
-
Chang YJ, Huang YP, Li ZL, Chen CH. GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells. PloS one 2012; 7:e35123; PMID:22529978; http://dx.doi.org/10.1371/journal.pone.0035123
-
(2012)
PloS one
, vol.7
-
-
Chang, Y.J.1
Huang, Y.P.2
Li, Z.L.3
Chen, C.H.4
-
123
-
-
84860468095
-
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling
-
PMID:22444729
-
Appenzeller-Herzog C, Hall MN. Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling. Trends Cell Biol 2012; 22:274-82; PMID:22444729; http://dx.doi.org/10.1016/j.tcb.2012.02.006
-
(2012)
Trends Cell Biol
, vol.22
, pp. 274-282
-
-
Appenzeller-Herzog, C.1
Hall, M.N.2
-
124
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
PMID:12172553
-
Inoki K, Li Y, Zhu T, Wu J, Guan KL. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 2002; 4:648-57; PMID:12172553; http://dx.doi.org/10.1038/ncb839
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
125
-
-
65949106140
-
Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner
-
PMID:19420259
-
Di Nardo A, Kramvis I, Cho N, Sadowski A, Meikle L, Kwiatkowski DJ, Sahin M. Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner. J Neurosci 2009; 29:5926-37; PMID:19420259; http://dx. doi.org/10.1523/JNEUROSCI.0778-09.2009
-
(2009)
J Neurosci
, vol.29
, pp. 5926-5937
-
-
Di Nardo, A.1
Kramvis, I.2
Cho, N.3
Sadowski, A.4
Meikle, L.5
Kwiatkowski, D.J.6
Sahin, M.7
-
126
-
-
84923585428
-
Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine
-
PMID:25498902
-
Johnson CE, Hunt DK, Wiltshire M, Herbert TP, Sampson JR, Errington RJ, Davies DM, Tee AR. Endoplasmic reticulum stress and cell death in mTORC1-overactive cells is induced by nelfinavir and enhanced by chloroquine. Mol Oncol 2015; 9:675-88; PMID:25498902; http://dx.doi.org/10.1016/j.molonc.2014.11.005
-
(2015)
Mol Oncol
, vol.9
, pp. 675-688
-
-
Johnson, C.E.1
Hunt, D.K.2
Wiltshire, M.3
Herbert, T.P.4
Sampson, J.R.5
Errington, R.J.6
Davies, D.M.7
Tee, A.R.8
-
127
-
-
63049095364
-
Activating transcription factor 4 and CCAAT/enhancer-binding proteinb negatively regulate the mammalian target of rapamycin via Redd1 expression in response to oxidative and endoplasmic reticulum stress
-
PMID:19439225
-
Jin HO, Seo SK, Woo SH, Kim ES, Lee HC, Yoo DH, An S, Choe TB, Lee SJ, Hong SI, et al. Activating transcription factor 4 and CCAAT/enhancer-binding proteinb negatively regulate the mammalian target of rapamycin via Redd1 expression in response to oxidative and endoplasmic reticulum stress. Free Radica Biol Med 2009; 46:1158-67; PMID:19439225; http://dx.doi.org/10.1016/j.freeradbiomed.2009.01.015
-
(2009)
Free Radica Biol Med
, vol.46
, pp. 1158-1167
-
-
Jin, H.O.1
Seo, S.K.2
Woo, S.H.3
Kim, E.S.4
Lee, H.C.5
Yoo, D.H.6
An, S.7
Choe, T.B.8
Lee, S.J.9
Hong, S.I.10
-
128
-
-
0026828422
-
IL-2 potentiates the IL-3 production by ConA activated mouse splenic T cells
-
Wu J, Wang ML, Qiu SL, Han JK, Zhu DX. IL-2 potentiates the IL-3 production by ConA activated mouse splenic T cells. Shi Yan Sheng Wu Xue Bao 1992; 25:25-30
-
(1992)
Shi Yan Sheng Wu Xue Bao
, vol.25
, pp. 25-30
-
-
Wu, J.1
Wang, M.L.2
Qiu, S.L.3
Han, J.K.4
Zhu, D.X.5
-
129
-
-
84867852387
-
Induction of REDD1 gene expression in the liver in response to endoplasmic reticulum stress is mediated through a PERK, eIF2alpha phosphorylation, ATF4-dependent cascade
-
PMID:23000413
-
Kimball SR, Jefferson LS. Induction of REDD1 gene expression in the liver in response to endoplasmic reticulum stress is mediated through a PERK, eIF2alpha phosphorylation, ATF4-dependent cascade. Biochem Biophys Res Commun 2012; 427:485-9; PMID:23000413; http://dx.doi.org/10.1016/j. bbrc.2012.09.074
-
(2012)
Biochem Biophys Res Commun
, vol.427
, pp. 485-489
-
-
Kimball, S.R.1
Jefferson, L.S.2
-
130
-
-
84855696465
-
mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway
-
PMID:21779001
-
Kato H, Nakajima S, Saito Y, Takahashi S, Katoh R, Kitamura M. mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway. Cell Death Differ 2012; 19:310-20; PMID:21779001; http://dx.doi.org/10.1038/cdd.2011.98
-
(2012)
Cell Death Differ
, vol.19
, pp. 310-320
-
-
Kato, H.1
Nakajima, S.2
Saito, Y.3
Takahashi, S.4
Katoh, R.5
Kitamura, M.6
-
131
-
-
78650174233
-
The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis
-
PMID:20616807
-
Kang YJ, Lu MK, Guan KL. The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis. Cell Death Differ 2011; 18:133-44; PMID:20616807; http://dx.doi. org/10.1038/cdd.2010.82
-
(2011)
Cell Death Differ
, vol.18
, pp. 133-144
-
-
Kang, Y.J.1
Lu, M.K.2
Guan, K.L.3
-
132
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
PMID:19425170
-
Salazar M, Carracedo A, Salanueva IJ, Hernandez-Tiedra S, Lorente M, Egia A, Vázquez P, Blázquez C, Torres S, García S, et al. Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest 2009; 119:1359-72; PMID:19425170http://dx.doi.org/10.1172/JCI37948
-
(2009)
J Clin Invest
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
Carracedo, A.2
Salanueva, I.J.3
Hernandez-Tiedra, S.4
Lorente, M.5
Egia, A.6
Vázquez, P.7
Blázquez, C.8
Torres, S.9
García, S.10
-
133
-
-
17144417669
-
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
-
PMID:15775988
-
Ohoka N, Yoshii S, Hattori T, Onozaki K, Hayashi H. TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. EMBO J 2005; 24:1243-55; PMID:15775988; http://dx. doi.org/10.1038/sj.emboj.7600596
-
(2005)
EMBO J
, vol.24
, pp. 1243-1255
-
-
Ohoka, N.1
Yoshii, S.2
Hattori, T.3
Onozaki, K.4
Hayashi, H.5
-
134
-
-
34447503956
-
TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway
-
PMID:17369260
-
Jousse C, Deval C, Maurin AC, Parry L, Cherasse Y, Chaveroux C, Lefloch R, Lenormand P, Bruhat A, Fafournoux P. TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway. J Biol Chem 2007; 282:15851-61; PMID:17369260; http://dx.doi.org/10.1074/jbc.M611723200
-
(2007)
J Biol Chem
, vol.282
, pp. 15851-15861
-
-
Jousse, C.1
Deval, C.2
Maurin, A.C.3
Parry, L.4
Cherasse, Y.5
Chaveroux, C.6
Lefloch, R.7
Lenormand, P.8
Bruhat, A.9
Fafournoux, P.10
-
135
-
-
84890149646
-
Where is mTOR and what is it doing there?
-
PMID:24385483
-
Betz C, Hall MN. Where is mTOR and what is it doing there? J cell Biol 2013; 203:563-74; PMID:24385483; http://dx.doi.org/10.1083/jcb.201306041
-
(2013)
J cell Biol
, vol.203
, pp. 563-574
-
-
Betz, C.1
Hall, M.N.2
-
136
-
-
79952119614
-
ER stress inhibits mTORC2 and Akt signaling through GSK-3beta-mediated phosphorylation of rictor
-
PMID:21343617
-
Chen CH, Shaikenov T, Peterson TR, Aimbetov R, Bissenbaev AK, Lee SW, Wu J, Lin HK, Sarbassov dos D. ER stress inhibits mTORC2 and Akt signaling through GSK-3beta-mediated phosphorylation of rictor. Sci Signal 2011; 4:ra10; PMID:21343617; http://dx.doi.org/10.1126/scisignal.2001731
-
(2011)
Sci Signal
, vol.4
-
-
Chen, C.H.1
Shaikenov, T.2
Peterson, T.R.3
Aimbetov, R.4
Bissenbaev, A.K.5
Lee, S.W.6
Wu, J.7
Lin, H.K.8
Sarbassov dos, D.9
-
137
-
-
84875765138
-
Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3beta-dependent inhibition of apoptosis and ER stress
-
PMID:23474308
-
Dong M, Hu N, Hua Y, Xu X, Kandadi MR, Guo R, Jiang S, Nair S, Hu D, Ren J. Chronic Akt activation attenuated lipopolysaccharide-induced cardiac dysfunction via Akt/GSK3beta-dependent inhibition of apoptosis and ER stress. Biochim Biophys Acta 2013; 1832:848-63; PMID:23474308; http://dx.doi.org/10.1016/j.bbadis.2013.02.023
-
(2013)
Biochim Biophys Acta
, vol.1832
, pp. 848-863
-
-
Dong, M.1
Hu, N.2
Hua, Y.3
Xu, X.4
Kandadi, M.R.5
Guo, R.6
Jiang, S.7
Nair, S.8
Hu, D.9
Ren, J.10
-
138
-
-
63849149937
-
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth
-
PMID:19245654
-
Shaw RJ. LKB1 and AMP-activated protein kinase control of mTOR signalling and growth. Acta Physiol (Oxf) 2009; 196:65-80; PMID:19245654; http://dx. doi.org/10.1111/j.1748-1716.2009.01972.x
-
(2009)
Acta Physiol (Oxf)
, vol.196
, pp. 65-80
-
-
Shaw, R.J.1
-
139
-
-
79251587803
-
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
-
PMID:21205641
-
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, et al. Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science 2011; 331:456-61; PMID:21205641; http://dx.doi.org/10.1126/science.1196371
-
(2011)
Science
, vol.331
, pp. 456-461
-
-
Egan, D.F.1
Shackelford, D.B.2
Mihaylova, M.M.3
Gelino, S.4
Kohnz, R.A.5
Mair, W.6
Vasquez, D.S.7
Joshi, A.8
Gwinn, D.M.9
Taylor, R.10
-
140
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
PMID:21258367
-
Kim J, Kundu M, Viollet B, Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 2011; 13:132-41; PMID:21258367; http://dx.doi.org/10.1038/ncb2152
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
141
-
-
84871618876
-
Activation of AMP-activated protein kinase inhibits albumin-induced endoplasmic reticulum stress and apoptosis through inhibition of reactive oxygen species
-
PMID:23108012
-
Lee EK, Jeong JU, Chang JW, Yang WS, Kim SB, Park SK, Park JS, Lee SK. Activation of AMP-activated protein kinase inhibits albumin-induced endoplasmic reticulum stress and apoptosis through inhibition of reactive oxygen species. Nephron Exp Nephrol 2012; 121:e38-48; PMID:23108012; http://dx.doi.org/10.1159/000342802
-
(2012)
Nephron Exp Nephrol
, vol.121
, pp. e38-e48
-
-
Lee, E.K.1
Jeong, J.U.2
Chang, J.W.3
Yang, W.S.4
Kim, S.B.5
Park, S.K.6
Park, J.S.7
Lee, S.K.8
-
142
-
-
27144489669
-
AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress
-
PMID:16227605
-
Terai K, Hiramoto Y, Masaki M, Sugiyama S, Kuroda T, Hori M, Kawase I, Hirota H. AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress. Mol Cell Biol 2005; 25:9554-75; PMID:16227605; http://dx.doi.org/10.1128/MCB.25.21.9554-9575.2005
-
(2005)
Mol Cell Biol
, vol.25
, pp. 9554-9575
-
-
Terai, K.1
Hiramoto, Y.2
Masaki, M.3
Sugiyama, S.4
Kuroda, T.5
Hori, M.6
Kawase, I.7
Hirota, H.8
-
143
-
-
84864059240
-
Metformin accelerates the growth of BRAF V600E-driven melanoma by upregulating VEGF-A
-
PMID:22576211
-
Martin MJ, Hayward R, Viros A, Marais R. Metformin accelerates the growth of BRAF V600E-driven melanoma by upregulating VEGF-A. Cancer Discov 2012; 2:344-55; PMID:22576211; http://dx.doi.org/10.1158/2159-8290.CD-11-0280
-
(2012)
Cancer Discov
, vol.2
, pp. 344-355
-
-
Martin, M.J.1
Hayward, R.2
Viros, A.3
Marais, R.4
-
144
-
-
84878231533
-
Ultraviolet (UV) and Hydrogen Peroxide Activate Ceramide-ER Stress-AMPK Signaling Axis to Promote Retinal Pigment Epithelium (RPE) Cell Apoptosis
-
PMID:23685869
-
Yao J, Bi HE, Sheng Y, Cheng LB, Wendu RL, Wang CH, Cao GF, Jiang Q. Ultraviolet (UV) and Hydrogen Peroxide Activate Ceramide-ER Stress-AMPK Signaling Axis to Promote Retinal Pigment Epithelium (RPE) Cell Apoptosis. Int J Mol Sci 2013; 14:10355-68; PMID:23685869; http://dx.doi.org/10.3390/ijms140510355
-
(2013)
Int J Mol Sci
, vol.14
, pp. 10355-10368
-
-
Yao, J.1
Bi, H.E.2
Sheng, Y.3
Cheng, L.B.4
Wendu, R.L.5
Wang, C.H.6
Cao, G.F.7
Jiang, Q.8
-
145
-
-
84877578475
-
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
-
PMID:23624402
-
Han J, Back SH, Hur J, Lin YH, Gildersleeve R, Shan J, Yuan CL, Krokowski D, Wang S, Hatzoglou M, et al. ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat Cell Biol 2013; 15:481-90; PMID:23624402; http://dx.doi.org/10.1038/ncb2738
-
(2013)
Nat Cell Biol
, vol.15
, pp. 481-490
-
-
Han, J.1
Back, S.H.2
Hur, J.3
Lin, Y.H.4
Gildersleeve, R.5
Shan, J.6
Yuan, C.L.7
Krokowski, D.8
Wang, S.9
Hatzoglou, M.10
-
146
-
-
84896721859
-
Bufalin induces the interplay between apoptosis and autophagy in glioma cells through endoplasmic reticulum stress
-
PMID:24550689
-
Shen S, Zhang Y, Wang Z, Liu R, Gong X. Bufalin induces the interplay between apoptosis and autophagy in glioma cells through endoplasmic reticulum stress. Int J Biol Sci 2014; 10:212-24; PMID:24550689; http://dx.doi.org/10.7150/ijbs.8056
-
(2014)
Int J Biol Sci
, vol.10
, pp. 212-224
-
-
Shen, S.1
Zhang, Y.2
Wang, Z.3
Liu, R.4
Gong, X.5
-
147
-
-
84885582468
-
Regulation of autophagy during ECMdetachment is linked to a selective inhibition of mTORC1 by PERK
-
PMID:23160380
-
Avivar-Valderas A, Bobrovnikova-Marjon E, Alan Diehl J, Bardeesy N, Debnath J, Aguirre-Ghiso JA. Regulation of autophagy during ECMdetachment is linked to a selective inhibition of mTORC1 by PERK. Oncogene 2013; 32:4932-40; PMID:23160380; http://dx.doi.org/10.1038/onc.2012.512
-
(2013)
Oncogene
, vol.32
, pp. 4932-4940
-
-
Avivar-Valderas, A.1
Bobrovnikova-Marjon, E.2
Alan Diehl, J.3
Bardeesy, N.4
Debnath, J.5
Aguirre-Ghiso, J.A.6
-
148
-
-
0028283948
-
Molecular and cellular physiology of intracellular calcium stores
-
PMID:8036248
-
Pozzan T, Rizzuto R, Volpe P, Meldolesi J. Molecular and cellular physiology of intracellular calcium stores. Physiol Rev 1994; 74:595-636; PMID:8036248
-
(1994)
Physiol Rev
, vol.74
, pp. 595-636
-
-
Pozzan, T.1
Rizzuto, R.2
Volpe, P.3
Meldolesi, J.4
-
149
-
-
80054776671
-
Endoplasmic-reticulum calcium depletion and disease
-
Mekahli D, Bultynck G, Parys JB, De Smedt H, Missiaen L. Endoplasmic-reticulum calcium depletion and disease. Cold Spring Harb Perspect Biol 2011; 3: a004317; http://dx.doi.org/10.1101/cshperspect. a004317
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
-
-
Mekahli, D.1
Bultynck, G.2
Parys, J.B.3
De Smedt, H.4
Missiaen, L.5
-
150
-
-
33846189759
-
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-b, and Bcl-2
-
PMID:17244528
-
Hoyer-Hansen M, Bastholm L, Szyniarowski P, Campanella M, Szabadkai G, Farkas T, Bianchi K, Fehrenbacher N, Elling F, Rizzuto R, et al. Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-b, and Bcl-2. Mol Cell 2007; 25:193-205; PMID:17244528; http://dx.doi.org/10.1016/j. molcel.2006.12.009
-
(2007)
Mol Cell
, vol.25
, pp. 193-205
-
-
Hoyer-Hansen, M.1
Bastholm, L.2
Szyniarowski, P.3
Campanella, M.4
Szabadkai, G.5
Farkas, T.6
Bianchi, K.7
Fehrenbacher, N.8
Elling, F.9
Rizzuto, R.10
-
151
-
-
79251534395
-
Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes
-
PMID:21191072
-
Jia W, Pua HH, Li QJ, He YW. Autophagy regulates endoplasmic reticulum homeostasis and calcium mobilization in T lymphocytes. J Immunol 2011; 186:1564-74; PMID:21191072; http://dx.doi.org/10.4049/jimmunol.1001822
-
(2011)
J Immunol
, vol.186
, pp. 1564-1574
-
-
Jia, W.1
Pua, H.H.2
Li, Q.J.3
He, Y.W.4
-
152
-
-
50249137038
-
Induction of macroautophagy by exogenously introduced calcium
-
PMID:18560273
-
Gao W, Ding WX, Stolz DB, Yin XM. Induction of macroautophagy by exogenously introduced calcium. Autophagy 2008; 4:754-61; PMID:18560273; http://dx.doi.org/10.4161/auto.6360
-
(2008)
Autophagy
, vol.4
, pp. 754-761
-
-
Gao, W.1
Ding, W.X.2
Stolz, D.B.3
Yin, X.M.4
-
153
-
-
84871354290
-
Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis
-
PMID:23285000
-
Chen X, Li M, Chen D, Gao W, Guan JL, Komatsu M, Yin XM. Autophagy induced by calcium phosphate precipitates involves endoplasmic reticulum membranes in autophagosome biogenesis. PloS One 2012; 7:e52347; PMID:23285000; http://dx.doi.org/10.1371/journal.pone.0052347
-
(2012)
PloS One
, vol.7
-
-
Chen, X.1
Li, M.2
Chen, D.3
Gao, W.4
Guan, J.L.5
Komatsu, M.6
Yin, X.M.7
-
154
-
-
34247380330
-
Regulation of autophagy by the inositol trisphosphate receptor
-
PMID:17256008
-
Criollo A, Maiuri MC, Tasdemir E, Vitale I, Fiebig AA, Andrews D, Molgó J, Díaz J, Lavandero S, Harper F, et al. Regulation of autophagy by the inositol trisphosphate receptor. Cell Death Differ 2007; 14:1029-39; PMID:17256008
-
(2007)
Cell Death Differ
, vol.14
, pp. 1029-1039
-
-
Criollo, A.1
Maiuri, M.C.2
Tasdemir, E.3
Vitale, I.4
Fiebig, A.A.5
Andrews, D.6
Molgó, J.7
Díaz, J.8
Lavandero, S.9
Harper, F.10
-
155
-
-
25444483066
-
Lithium induces autophagy by inhibiting inositol monophosphatase
-
PMID:16186256
-
Sarkar S, Floto RA, Berger Z, Imarisio S, Cordenier A, Pasco M, Cook LJ, Rubinsztein DC. Lithium induces autophagy by inhibiting inositol monophosphatase. J Cell Biol 2005; 170:1101-11; PMID:16186256; http://dx.doi. org/10.1083/jcb.200504035
-
(2005)
J Cell Biol
, vol.170
, pp. 1101-1111
-
-
Sarkar, S.1
Floto, R.A.2
Berger, Z.3
Imarisio, S.4
Cordenier, A.5
Pasco, M.6
Cook, L.J.7
Rubinsztein, D.C.8
-
156
-
-
63249083149
-
2+ channels in endoplasmic reticulum stress and b-cell death
-
PMID:19033399
-
2+ channels in endoplasmic reticulum stress and b-cell death. Diabetes 2009; 58:422-32; PMID:19033399; http://dx. doi.org/10.2337/db07-1762
-
(2009)
Diabetes
, vol.58
, pp. 422-432
-
-
Luciani, D.S.1
Gwiazda, K.S.2
Yang, T.L.3
Kalynyak, T.B.4
Bychkivska, Y.5
Frey, M.H.6
Jeffrey, K.D.7
Sampaio, A.V.8
Underhill, T.M.9
Johnson, J.D.10
-
157
-
-
77952759763
-
Role of inositol trisphosphate receptors in autophagy in DT40 cells
-
PMID:20308071
-
Khan MT, Joseph SK. Role of inositol trisphosphate receptors in autophagy in DT40 cells. J Biol Chem 2010; 285:16912-20; PMID:20308071; http://dx. doi.org/10.1074/jbc.M110.114207
-
(2010)
J Biol Chem
, vol.285
, pp. 16912-16920
-
-
Khan, M.T.1
Joseph, S.K.2
-
158
-
-
27144458505
-
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
-
PMID:16148948
-
Bi M, Naczki C, Koritzinsky M, Fels D, Blais J, Hu N, Harding H, Novoa I, Varia M, Raleigh J, et al. ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. EMBO J 2005; 24:3470-81; PMID:16148948; http://dx.doi. org/10.1038/sj.emboj.7600777
-
(2005)
EMBO J
, vol.24
, pp. 3470-3481
-
-
Bi, M.1
Naczki, C.2
Koritzinsky, M.3
Fels, D.4
Blais, J.5
Hu, N.6
Harding, H.7
Novoa, I.8
Varia, M.9
Raleigh, J.10
-
159
-
-
32444433450
-
Hypoxia-induced energy stress regulates mRNA translation and cell growth
-
PMID:16483933
-
Liu L, Cash TP, Jones RG, Keith B, Thompson CB, Simon MC. Hypoxia-induced energy stress regulates mRNA translation and cell growth. Mol Cell 2006; 21:521-31; PMID:16483933; http://dx.doi.org/10.1016/j.molcel.2006.01.010
-
(2006)
Mol Cell
, vol.21
, pp. 521-531
-
-
Liu, L.1
Cash, T.P.2
Jones, R.G.3
Keith, B.4
Thompson, C.B.5
Simon, M.C.6
-
160
-
-
81555210958
-
2+/calmodulin-dependent kinase (CaMK) signaling via CaMKI and AMP-activated protein kinase contributes to the regulation of WIPI-1 at the onset of autophagy
-
PMID:21896713
-
2+/calmodulin-dependent kinase (CaMK) signaling via CaMKI and AMP-activated protein kinase contributes to the regulation of WIPI-1 at the onset of autophagy. Mol Pharmacol 2011; 80:1066-75; PMID:21896713; http://dx.doi.org/10.1124/mol.111.071761
-
(2011)
Mol Pharmacol
, vol.80
, pp. 1066-1075
-
-
Pfisterer, S.G.1
Mauthe, M.2
Codogno, P.3
Proikas-Cezanne, T.4
-
161
-
-
0036261146
-
Effect of hypoxia on calcium influx and calcium/calmodulin-dependent kinase activity in cortical neuronal nuclei of the guinea pig fetus during development
-
PMID:11967487
-
Maulik D, Ashraf QM, Mishra OP, Delivoria-Papadopoulos M. Effect of hypoxia on calcium influx and calcium/calmodulin-dependent kinase activity in cortical neuronal nuclei of the guinea pig fetus during development. Am J Obstetr Gynecol 2002; 186:658-62; PMID:11967487; http://dx.doi.org/10.1067/mob.2002.122392
-
(2002)
Am J Obstetr Gynecol
, vol.186
, pp. 658-662
-
-
Maulik, D.1
Ashraf, Q.M.2
Mishra, O.P.3
Delivoria-Papadopoulos, M.4
-
162
-
-
50249187551
-
Regulation of ER stressinduced macroautophagy by protein kinase C
-
PMID:18670192
-
Sakaki K, Kaufman RJ. Regulation of ER stressinduced macroautophagy by protein kinase C. Autophagy 2008; 4:841-3; PMID:18670192; http://dx.doi.org/10.4161/auto.6607
-
(2008)
Autophagy
, vol.4
, pp. 841-843
-
-
Sakaki, K.1
Kaufman, R.J.2
-
163
-
-
47249157360
-
Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum
-
PMID:18356160
-
Sakaki K, Wu J, Kaufman RJ. Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum. J Biol Chem 2008; 283:15370-80; PMID:18356160; http://dx.doi.org/10.1074/jbc.M710209200
-
(2008)
J Biol Chem
, vol.283
, pp. 15370-15380
-
-
Sakaki, K.1
Wu, J.2
Kaufman, R.J.3
-
164
-
-
84877101291
-
Intracellular signaling in ER stress-induced autophagy in skeletal muscle cells
-
PMID:23388382
-
Madaro L, Marrocco V, Carnio S, Sandri M, Bouche M. Intracellular signaling in ER stress-induced autophagy in skeletal muscle cells. FASEB J 2013; 27:1990-2000; PMID:23388382; http://dx.doi.org/10.1096/fj.12-215475
-
(2013)
FASEB J
, vol.27
, pp. 1990-2000
-
-
Madaro, L.1
Marrocco, V.2
Carnio, S.3
Sandri, M.4
Bouche, M.5
-
165
-
-
84883282553
-
Role of intracellular calcium in proteasome inhibitor-induced endoplasmic reticulum stress, autophagy, and cell death
-
PMID:23893020
-
Williams JA, Hou Y, Ni HM, Ding WX. Role of intracellular calcium in proteasome inhibitor-induced endoplasmic reticulum stress, autophagy, and cell death. Pharmaceutical Res 2013; 30:2279-89; PMID:23893020; http://dx.doi.org/10.1007/s11095-013-1139-8
-
(2013)
Pharmaceutical Res
, vol.30
, pp. 2279-2289
-
-
Williams, J.A.1
Hou, Y.2
Ni, H.M.3
Ding, W.X.4
-
166
-
-
84881565288
-
The lysosome: From waste bag to potential therapeutic target
-
PMID:23918283
-
Appelqvist H, Waster P, Kagedal K, Ollinger K. The lysosome: from waste bag to potential therapeutic target. J Mol Cell Biol 2013; 5:214-26; PMID:23918283; http://dx. doi.org/10.1093/jmcb/mjt022
-
(2013)
J Mol Cell Biol
, vol.5
, pp. 214-226
-
-
Appelqvist, H.1
Waster, P.2
Kagedal, K.3
Ollinger, K.4
-
167
-
-
84861122472
-
Endoplasmic reticulum protein BI-1 regulates Ca(2)(+)-mediated bioenergetics to promote autophagy
-
PMID:22588718
-
Sano R, Hou YC, Hedvat M, Correa RG, Shu CW, Krajewska M, Diaz PW, Tamble CM, Quarato G, Gottlieb RA, et al. Endoplasmic reticulum protein BI-1 regulates Ca(2)(+)-mediated bioenergetics to promote autophagy. Genes Dev 2012; 26:1041-54; PMID:22588718; http://dx.doi.org/10.1101/gad.184325.111
-
(2012)
Genes Dev
, vol.26
, pp. 1041-1054
-
-
Sano, R.1
Hou, Y.C.2
Hedvat, M.3
Correa, R.G.4
Shu, C.W.5
Krajewska, M.6
Diaz, P.W.7
Tamble, C.M.8
Quarato, G.9
Gottlieb, R.A.10
-
168
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
PMID:21189453
-
Johansen T, Lamark T. Selective autophagy mediated by autophagic adapter proteins. Autophagy 2011; 7:279-96; PMID:21189453; http://dx.doi.org/10.4161/auto.7.3.14487
-
(2011)
Autophagy
, vol.7
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
169
-
-
78650467974
-
Mechanisms of mitophagy
-
PMID:21179058
-
Youle RJ, Narendra DP. Mechanisms of mitophagy. Nat Rev Mol Cell Biol 2011; 12:9-14; PMID:21179058; http://dx.doi.org/10.1038/nrm3028
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 9-14
-
-
Youle, R.J.1
Narendra, D.P.2
-
170
-
-
69349102568
-
Selective types of autophagy in yeast
-
PMID:19264099
-
Kraft C, Reggiori F, Peter M. Selective types of autophagy in yeast. Biochim Biophys Acta 2009; 1793:1404-12; PMID:19264099; http://dx.doi.org/10.1016/j.bbamcr.2009.02.006
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 1404-1412
-
-
Kraft, C.1
Reggiori, F.2
Peter, M.3
-
171
-
-
84883414890
-
The LIR motif - Crucial for selective autophagy
-
PMID:23908376
-
Birgisdottir AB, Lamark T, Johansen T. The LIR motif - crucial for selective autophagy. J Cell Sci 2013; 126:3237-47; PMID:23908376
-
(2013)
J Cell Sci
, vol.126
, pp. 3237-3247
-
-
Birgisdottir, A.B.1
Lamark, T.2
Johansen, T.3
-
172
-
-
34548259958
-
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
PMID:17580304
-
Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282:24131-45; PMID:17580304; http://dx.doi.org/10.1074/jbc. M702824200
-
(2007)
J Biol Chem
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.A.5
Outzen, H.6
Øvervatn, A.7
Bjørkøy, G.8
Johansen, T.9
-
173
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
-
PMID:18083104
-
Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, et al. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 2007; 131:1149-63; PMID:18083104; http://dx.doi.org/10.1016/j.cell.2007.10.035
-
(2007)
Cell
, vol.131
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
Sou, Y.S.4
Ueno, T.5
Hara, T.6
Mizushima, N.7
Iwata, J.8
Ezaki, J.9
Murata, S.10
-
174
-
-
67650517556
-
NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets
-
PMID:19502794
-
Lamark T, Kirkin V, Dikic I, Johansen T. NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets. Cell Cycle 2009; 8:1986-90; PMID:19502794; http://dx.doi.org/10.4161/cc.8.13.8892
-
(2009)
Cell Cycle
, vol.8
, pp. 1986-1990
-
-
Lamark, T.1
Kirkin, V.2
Dikic, I.3
Johansen, T.4
-
175
-
-
84934449989
-
Regulation of endoplasmic reticulum turnover by selective autophagy
-
PMID:26040720
-
Khaminets A, Heinrich T, Mari M, Grumati P, Huebner AK, Akutsu M, Liebmann L, Stolz A, Nietzsche S, Koch N, et al. Regulation of endoplasmic reticulum turnover by selective autophagy. Nature 2015; 522:354-8; PMID:26040720; http://dx.doi. org/10.1038/nature14498
-
(2015)
Nature
, vol.522
, pp. 354-358
-
-
Khaminets, A.1
Heinrich, T.2
Mari, M.3
Grumati, P.4
Huebner, A.K.5
Akutsu, M.6
Liebmann, L.7
Stolz, A.8
Nietzsche, S.9
Koch, N.10
-
176
-
-
67650234499
-
NBR1 cooperates with p62 in selective autophagy of ubiquitinated targets
-
PMID:19398892
-
Kirkin V, Lamark T, Johansen T, Dikic I. NBR1 cooperates with p62 in selective autophagy of ubiquitinated targets. Autophagy 2009; 5:732-3; PMID:19398892; http://dx. doi.org/10.4161/auto.5.5.8566
-
(2009)
Autophagy
, vol.5
, pp. 732-733
-
-
Kirkin, V.1
Lamark, T.2
Johansen, T.3
Dikic, I.4
-
177
-
-
60849099049
-
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates
-
PMID:19250911
-
Kirkin V, Lamark T, Sou YS, Bjorkoy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, et al. A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell 2009; 33:505-16; PMID:19250911; http://dx.doi. org/10.1016/j.molcel.2009.01.020
-
(2009)
Mol Cell
, vol.33
, pp. 505-516
-
-
Kirkin, V.1
Lamark, T.2
Sou, Y.S.3
Bjorkoy, G.4
Nunn, J.L.5
Bruun, J.A.6
Shvets, E.7
McEwan, D.G.8
Clausen, T.H.9
Wild, P.10
-
178
-
-
67650246357
-
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy
-
PMID:19619494
-
Okamoto K, Kondo-Okamoto N, Ohsumi Y. Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 2009; 17:87-97; PMID:19619494; http://dx.doi. org/10.1016/j.devcel.2009.06.013
-
(2009)
Dev Cell
, vol.17
, pp. 87-97
-
-
Okamoto, K.1
Kondo-Okamoto, N.2
Ohsumi, Y.3
-
179
-
-
84871000478
-
The role of ALFY in selective autophagy
-
PMID:22653340
-
Isakson P, Holland P, Simonsen A. The role of ALFY in selective autophagy. Cell Death Differ 2013; 20:12-20; PMID:22653340; http://dx.doi.org/10.1038/cdd.2012.66
-
(2013)
Cell Death Differ
, vol.20
, pp. 12-20
-
-
Isakson, P.1
Holland, P.2
Simonsen, A.3
-
180
-
-
79959939343
-
BAG3 and friends: Co-chaperones in selective autophagy during aging and disease
-
PMID:21681022
-
Behl C. BAG3 and friends: co-chaperones in selective autophagy during aging and disease. Autophagy 2011; 7:795-8; PMID:21681022; http://dx.doi.org/10.4161/auto.7.7.15844
-
(2011)
Autophagy
, vol.7
, pp. 795-798
-
-
Behl, C.1
-
181
-
-
84907042769
-
ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery
-
PMID:25052096
-
Schuck S, Gallagher CM, Walter P. ER-phagy mediates selective degradation of endoplasmic reticulum independently of the core autophagy machinery. J Cell Sci 2014; 127:4078-88; PMID:25052096; http://dx.doi.org/10.1242/jcs.154716
-
(2014)
J Cell Sci
, vol.127
, pp. 4078-4088
-
-
Schuck, S.1
Gallagher, C.M.2
Walter, P.3
-
182
-
-
5444222234
-
XBP1: A link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum
-
PMID:15466483
-
Sriburi R, Jackowski S, Mori K, Brewer JW. XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. J Cell Biol 2004; 167:35-41; PMID:15466483; http://dx.doi.org/10.1083/jcb.200406136
-
(2004)
J Cell Biol
, vol.167
, pp. 35-41
-
-
Sriburi, R.1
Jackowski, S.2
Mori, K.3
Brewer, J.W.4
-
183
-
-
84907892583
-
Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy
-
PMID:25126734
-
Zhang X, Yuan Y, Jiang L, Zhang J, Gao J, Shen Z, Zheng Y, Deng T, Yan H, Li W, et al. Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy. Autophagy 2014; 10:1801-13; PMID:25126734; http://dx.doi.org/10.4161/auto.32136
-
(2014)
Autophagy
, vol.10
, pp. 1801-1813
-
-
Zhang, X.1
Yuan, Y.2
Jiang, L.3
Zhang, J.4
Gao, J.5
Shen, Z.6
Zheng, Y.7
Deng, T.8
Yan, H.9
Li, W.10
-
184
-
-
84878225746
-
Functional and morphological impact of ER stress on mitochondria
-
PMID:23629871
-
Vannuvel K, Renard P, Raes M, Arnould T. Functional and morphological impact of ER stress on mitochondria. J Cell Physiol 2013; 228:1802-18; PMID:23629871; http://dx.doi.org/10.1002/jcp.24360
-
(2013)
J Cell Physiol
, vol.228
, pp. 1802-1818
-
-
Vannuvel, K.1
Renard, P.2
Raes, M.3
Arnould, T.4
-
185
-
-
84889968303
-
p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling
-
PMID:24269898
-
Rubio N, Verrax J, Dewaele M, Verfaillie T, Johansen T, Piette J, Agostinis P. p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling. Free Radic Biol Med 2014; 67:292-303; PMID:24269898; http://dx.doi. org/10.1016/j.freeradbiomed.2013.11.010
-
(2014)
Free Radic Biol Med
, vol.67
, pp. 292-303
-
-
Rubio, N.1
Verrax, J.2
Dewaele, M.3
Verfaillie, T.4
Johansen, T.5
Piette, J.6
Agostinis, P.7
-
186
-
-
84860471873
-
Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
-
PMID:22337954
-
Vidal RL, Figueroa A, Court FA, Thielen P, Molina C, Wirth C, Caballero B, Kiffin R, Segura-Aguilar J, Cuervo AM, et al. Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy. Hum Mol Genet 2012; 21:2245-62; PMID:22337954; http://dx.doi.org/10.1093/hmg/dds040
-
(2012)
Hum Mol Genet
, vol.21
, pp. 2245-2262
-
-
Vidal, R.L.1
Figueroa, A.2
Court, F.A.3
Thielen, P.4
Molina, C.5
Wirth, C.6
Caballero, B.7
Kiffin, R.8
Segura-Aguilar, J.9
Cuervo, A.M.10
-
187
-
-
70349627027
-
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
-
PMID:19762508
-
Hetz C, Thielen P, Matus S, Nassif M, Court F, Kiffin R, Martinez G, Cuervo AM, Brown RH, Glimcher LH. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Genes Dev 2009; 23:2294-306; PMID:19762508; http://dx.doi.org/10.1101/gad.1830709
-
(2009)
Genes Dev
, vol.23
, pp. 2294-2306
-
-
Hetz, C.1
Thielen, P.2
Matus, S.3
Nassif, M.4
Court, F.5
Kiffin, R.6
Martinez, G.7
Cuervo, A.M.8
Brown, R.H.9
Glimcher, L.H.10
-
188
-
-
84911440935
-
Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: Involvement of the proteasome and ER stress-activated kinase IRE1alpha
-
PMID:24951540
-
Hyrskyluoto A, Bruelle C, Lundh SH, Do HT, Kivinen J, Rappou E, Reijonen S, Waltimo T, Petersén Å, Lindholm D, et al. Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1alpha. Hum Mol Genet 2014; 23:5928-39; PMID:24951540; http://dx.doi.org/10.1093/hmg/ddu317
-
(2014)
Hum Mol Genet
, vol.23
, pp. 5928-5939
-
-
Hyrskyluoto, A.1
Bruelle, C.2
Lundh, S.H.3
Do, H.T.4
Kivinen, J.5
Rappou, E.6
Reijonen, S.7
Waltimo, T.8
Petersén, Å.9
Lindholm, D.10
-
189
-
-
83455169115
-
IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux
-
PMID:21954231
-
Lee H, Noh JY, Oh Y, Kim Y, Chang JW, Chung CW, Lee ST, Kim M, Ryu H, Jung YK. IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux. Hum Mol Genet 2012; 21:101-14; PMID:21954231; http://dx.doi.org/10.1093/hmg/ddr445
-
(2012)
Hum Mol Genet
, vol.21
, pp. 101-114
-
-
Lee, H.1
Noh, J.Y.2
Oh, Y.3
Kim, Y.4
Chang, J.W.5
Chung, C.W.6
Lee, S.T.7
Kim, M.8
Ryu, H.9
Jung, Y.K.10
-
190
-
-
84892611707
-
The ubiquitin-specific protease 14 (USP14) is a critical regulator of long-term memory formation
-
Jarome TJ, Kwapis JL, Hallengren JJ, Wilson SM, Helmstetter FJ. The ubiquitin-specific protease 14 (USP14) is a critical regulator of long-term memory formation. Learn Mem 2014; 21:9-13
-
(2014)
Learn Mem
, vol.21
, pp. 9-13
-
-
Jarome, T.J.1
Kwapis, J.L.2
Hallengren, J.J.3
Wilson, S.M.4
Helmstetter, F.J.5
-
191
-
-
84864878724
-
Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy
-
PMID:22820375
-
van der Vos KE, Eliasson P, Proikas-Cezanne T, Vervoort SJ, van Boxtel R, Putker M, van Zutphen IJ, Mauthe M, Zellmer S, Pals C, et al. Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy. Nat Cell Biol 2012; 14:829-37; PMID:22820375; http://dx.doi.org/10.1038/ncb2536
-
(2012)
Nat Cell Biol
, vol.14
, pp. 829-837
-
-
van der Vos, K.E.1
Eliasson, P.2
Proikas-Cezanne, T.3
Vervoort, S.J.4
van Boxtel, R.5
Putker, M.6
van Zutphen, I.J.7
Mauthe, M.8
Zellmer, S.9
Pals, C.10
-
192
-
-
84929966579
-
Cell proliferation is a key determinant of the outcome of FOXO3a activation
-
PMID:25935481
-
Poulsen RC, Carr AJ, Hulley PA. Cell proliferation is a key determinant of the outcome of FOXO3a activation. Biochem Biophys Res Commun 2015; 462:78-84; PMID:25935481; http://dx.doi.org/10.1016/j. bbrc.2015.04.112
-
(2015)
Biochem Biophys Res Commun
, vol.462
, pp. 78-84
-
-
Poulsen, R.C.1
Carr, A.J.2
Hulley, P.A.3
-
193
-
-
0036839685
-
Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D
-
PMID:12391153
-
Schmidt M, Fernandez de Mattos S, van der Horst A, Klompmaker R, Kops GJ, Lam EW, Burgering BM, Medema RH. Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D. Mol Cell Biol 2002; 22:7842-52; PMID:12391153; http://dx.doi.org/10.1128/MCB.22.22.7842-7852.2002
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7842-7852
-
-
Schmidt, M.1
Fernandez de Mattos, S.2
van der Horst, A.3
Klompmaker, R.4
Kops, G.J.5
Lam, E.W.6
Burgering, B.M.7
Medema, R.H.8
-
194
-
-
84883515877
-
Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: Of gene prioritization and context dependence
-
PMID:23781200
-
Parmentier F, Lejeune FX, Neri C. Pathways to decoding the clinical potential of stress response FOXO-interaction networks for Huntington's disease: of gene prioritization and context dependence. Frontiers Aging Neurosci 2013; 5:22; PMID:23781200; http://dx.doi.org/10.3389/fnagi.2013.00022
-
(2013)
Frontiers Aging Neurosci
, vol.5
, pp. 22
-
-
Parmentier, F.1
Lejeune, F.X.2
Neri, C.3
-
195
-
-
41549135942
-
FoxO transcription factors in the maintenance of cellular homeostasis during aging
-
PMID:18394876
-
Salih DA, Brunet A. FoxO transcription factors in the maintenance of cellular homeostasis during aging. Curr Opin Cell Biol 2008; 20:126-36; PMID:18394876; http://dx.doi.org/10.1016/j. ceb.2008.02.005
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 126-136
-
-
Salih, D.A.1
Brunet, A.2
-
196
-
-
41849128523
-
The FoxO code
-
PMID:18391970
-
Calnan DR, Brunet A. The FoxO code. Oncogene 2008; 27:2276-88; PMID:18391970; http://dx.doi. org/10.1038/onc.2008.21
-
(2008)
Oncogene
, vol.27
, pp. 2276-2288
-
-
Calnan, D.R.1
Brunet, A.2
-
197
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
PMID:10102273
-
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 1999; 96:857-68; PMID:10102273; http://dx.doi. org/10.1016/S0092-8674(00)80595-4
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
198
-
-
0034661826
-
Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues
-
PMID:10880363
-
Furuyama T, Nakazawa T, Nakano I, Mori N. Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochemical J 2000; 349:629-34; PMID:10880363; http://dx.doi.org/10.1042/bj3490629
-
(2000)
Biochemical J
, vol.349
, pp. 629-634
-
-
Furuyama, T.1
Nakazawa, T.2
Nakano, I.3
Mori, N.4
-
199
-
-
0033595011
-
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
-
Biggs WH, 3rd, Meisenhelder J, Hunter T, Cavenee WK, Arden KC. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc Natl Acad Sci USA 1999; 96:7421-6
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7421-7426
-
-
Biggs, W.H.1
Meisenhelder, J.2
Hunter, T.3
Cavenee, W.K.4
Arden, K.C.5
-
200
-
-
84880415788
-
Forkhead box class O transcription factors in liver function and disease
-
PMID:23855308
-
Tikhanovich I, Cox J, Weinman SA. Forkhead box class O transcription factors in liver function and disease. J Gastroenterol Hepatol 2013; 28 Suppl 1:125-31; PMID:23855308; http://dx.doi.org/10.1111/jgh.12021
-
(2013)
J Gastroenterol Hepatol
, vol.28
, pp. 125-131
-
-
Tikhanovich, I.1
Cox, J.2
Weinman, S.A.3
-
201
-
-
0037018148
-
Fourteen-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport
-
PMID:11864996
-
Brunet A, Kanai F, Stehn J, Xu J, Sarbassova D, Frangioni JV, Dalal SN, DeCaprio JA, Greenberg ME, Yaffe MB. Fourteen-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport. J Cell Biol 2002; 156:817-28; PMID:11864996; http://dx.doi.org/10.1083/jcb.200112059
-
(2002)
J Cell Biol
, vol.156
, pp. 817-828
-
-
Brunet, A.1
Kanai, F.2
Stehn, J.3
Xu, J.4
Sarbassova, D.5
Frangioni, J.V.6
Dalal, S.N.7
DeCaprio, J.A.8
Greenberg, M.E.9
Yaffe, M.B.10
-
202
-
-
23944495537
-
Fourteen-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4
-
PMID:16114898
-
Obsilova V, Vecer J, Herman P, Pabianova A, Sulc M, Teisinger J, Boura E, Obsil T. Fourteen-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4. Biochemistry 2005; 44:11608-17; PMID:16114898; http://dx.doi.org/10.1021/bi050618r
-
(2005)
Biochemistry
, vol.44
, pp. 11608-11617
-
-
Obsilova, V.1
Vecer, J.2
Herman, P.3
Pabianova, A.4
Sulc, M.5
Teisinger, J.6
Boura, E.7
Obsil, T.8
-
203
-
-
79951720176
-
JNK regulates FoxOdependent autophagy in neurons
-
PMID:21325132
-
Xu P, Das M, Reilly J, Davis RJ. JNK regulates FoxOdependent autophagy in neurons. Genes Dev 2011; 25:310-22; PMID:21325132; http://dx.doi.org/10.1101/gad.1984311
-
(2011)
Genes Dev
, vol.25
, pp. 310-322
-
-
Xu, P.1
Das, M.2
Reilly, J.3
Davis, R.J.4
-
204
-
-
79952381078
-
Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction
-
PMID:21317886
-
Zhou Y, Lee J, Reno CM, Sun C, Park SW, Chung J, Lee J, Fisher SJ, White MF, Biddinger SB, et al. Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction. Nature Med 2011; 17:356-65; PMID:21317886; http://dx.doi.org/10.1038/nm.2293
-
(2011)
Nature Med
, vol.17
, pp. 356-365
-
-
Zhou, Y.1
Lee, J.2
Reno, C.M.3
Sun, C.4
Park, S.W.5
Chung, J.6
Lee, J.7
Fisher, S.J.8
White, M.F.9
Biddinger, S.B.10
-
205
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
PMID:12050113
-
Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 2002; 16:1345-55; PMID:12050113; http://dx.doi.org/10.1101/gad.992302
-
(2002)
Genes Dev
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
Hori, S.7
Kakizuka, A.8
Ichijo, H.9
-
206
-
-
73449097110
-
XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy
-
PMID:19855189
-
Matus S, Nassif M, Glimcher LH, Hetz C. XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy. Autophagy 2009; 5:1226-8; PMID:19855189; http://dx.doi.org/10.4161/auto.5.8.10247
-
(2009)
Autophagy
, vol.5
, pp. 1226-1228
-
-
Matus, S.1
Nassif, M.2
Glimcher, L.H.3
Hetz, C.4
-
207
-
-
84901062946
-
Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD
-
Gonzalez-Rodriguez A, Mayoral R, Agra N, Valdecantos MP, Pardo V, Miquilena-Colina ME, Vargas-Castrillón J, Lo Iacono O, Corazzari M, Fimia GM, et al. Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD. Cell Death Dis 2014; 5: e1179; http://dx.doi.org/10.1038/cddis.2014.162
-
(2014)
Cell Death Dis
, vol.5
-
-
Gonzalez-Rodriguez, A.1
Mayoral, R.2
Agra, N.3
Valdecantos, M.P.4
Pardo, V.5
Miquilena-Colina, M.E.6
Vargas-Castrillón, J.7
Lo Iacono, O.8
Corazzari, M.9
Fimia, G.M.10
-
208
-
-
66449112462
-
SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition
-
PMID:19240033
-
Noh JY, Lee H, Song S, Kim NS, Im W, Kim M, Seo H, Chung CW, Chang JW, Ferrante RJ, et al. SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition. J Biol Chem 2009; 284:11318-25; PMID:19240033; http://dx. doi.org/10.1074/jbc.M807620200
-
(2009)
J Biol Chem
, vol.284
, pp. 11318-11325
-
-
Noh, J.Y.1
Lee, H.2
Song, S.3
Kim, N.S.4
Im, W.5
Kim, M.6
Seo, H.7
Chung, C.W.8
Chang, J.W.9
Ferrante, R.J.10
-
209
-
-
0035105295
-
The stressinduced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex
-
PMID:11239470
-
Cavalli V, Vilbois F, Corti M, Marcote MJ, Tamura K, Karin M, Arkinstall S, Gruenberg J. The stressinduced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex. Mol Cell 2001; 7:421-32; PMID:11239470; http://dx.doi.org/10.1016/S1097-2765(01)00189-7
-
(2001)
Mol Cell
, vol.7
, pp. 421-432
-
-
Cavalli, V.1
Vilbois, F.2
Corti, M.3
Marcote, M.J.4
Tamura, K.5
Karin, M.6
Arkinstall, S.7
Gruenberg, J.8
-
210
-
-
84876408458
-
Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion
-
PMID:23337583
-
Zhou J, Tan SH, Nicolas V, Bauvy C, Yang ND, Zhang J, Xue Y, Codogno P, Shen HM. Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion. Cell Res 2013; 23:508-23; PMID:23337583; http://dx.doi.org/10.1038/cr.2013.11
-
(2013)
Cell Res
, vol.23
, pp. 508-523
-
-
Zhou, J.1
Tan, S.H.2
Nicolas, V.3
Bauvy, C.4
Yang, N.D.5
Zhang, J.6
Xue, Y.7
Codogno, P.8
Shen, H.M.9
-
211
-
-
42249106042
-
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
-
PMID:18391949
-
Williams A, Sarkar S, Cuddon P, Ttofi EK, Saiki S, Siddiqi FH, Jahreiss L, Fleming A, Pask D, Goldsmith P, et al. Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nat Chem Biol 2008; 4:295-305; PMID:18391949; http://dx.doi.org/10.1038/nchembio.79
-
(2008)
Nat Chem Biol
, vol.4
, pp. 295-305
-
-
Williams, A.1
Sarkar, S.2
Cuddon, P.3
Ttofi, E.K.4
Saiki, S.5
Siddiqi, F.H.6
Jahreiss, L.7
Fleming, A.8
Pask, D.9
Goldsmith, P.10
-
212
-
-
79959346132
-
Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest
-
PMID:21700220
-
Ganley IG, Wong PM, Gammoh N, Jiang X. Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest. Mol Cell 2011; 42:731-43; PMID:21700220; http://dx.doi.org/10.1016/j.molcel.2011.04.024
-
(2011)
Mol Cell
, vol.42
, pp. 731-743
-
-
Ganley, I.G.1
Wong, P.M.2
Gammoh, N.3
Jiang, X.4
-
213
-
-
77949915406
-
2+ increase
-
PMID:20114074
-
2+ increase. Cell Signal 2010; 22:914-25; PMID:20114074; http://dx.doi.org/10.1016/j.cellsig.2010.01.015
-
(2010)
Cell Signal
, vol.22
, pp. 914-925
-
-
Grotemeier, A.1
Alers, S.2
Pfisterer, S.G.3
Paasch, F.4
Daubrawa, M.5
Dieterle, A.6
Viollet, B.7
Wesselborg, S.8
Proikas-Cezanne, T.9
Stork, B.10
-
214
-
-
84885664839
-
Modulation of intracellular calcium homeostasis blocks autophagosome formation
-
PMID:23970164
-
Engedal N, Torgersen ML, Guldvik IJ, Barfeld SJ, Bakula D, Saetre F, Hagen LK, Patterson JB, Proikas-Cezanne T, Seglen PO, et al. Modulation of intracellular calcium homeostasis blocks autophagosome formation. Autophagy 2013; 9:1475-90; PMID:23970164; http://dx.doi.org/10.4161/auto.25900
-
(2013)
Autophagy
, vol.9
, pp. 1475-1490
-
-
Engedal, N.1
Torgersen, M.L.2
Guldvik, I.J.3
Barfeld, S.J.4
Bakula, D.5
Saetre, F.6
Hagen, L.K.7
Patterson, J.B.8
Proikas-Cezanne, T.9
Seglen, P.O.10
-
215
-
-
80055089069
-
Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice
-
Yu Z, Wang AM, Adachi H, Katsuno M, Sobue G, Yue Z, Robins DM, Lieberman AP. Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice. PLoS Genet 2011; 7:e1002321
-
(2011)
PLoS Genet
, vol.7
-
-
Yu, Z.1
Wang, A.M.2
Adachi, H.3
Katsuno, M.4
Sobue, G.5
Yue, Z.6
Robins, D.M.7
Lieberman, A.P.8
-
216
-
-
84885190019
-
AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: A role for melatonin and trimetazidine cocktail
-
PMID:23551302
-
Zaouali MA, Boncompagni E, Reiter RJ, Bejaoui M, Freitas I, Pantazi E, Folch-Puy E, Abdennebi HB, Garcia-Gil FA, Roselló-Catafau J. AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail. J Pineal Res 2013; 55:65-78; PMID:23551302; http://dx.doi.org/10.1111/jpi.12051
-
(2013)
J Pineal Res
, vol.55
, pp. 65-78
-
-
Zaouali, M.A.1
Boncompagni, E.2
Reiter, R.J.3
Bejaoui, M.4
Freitas, I.5
Pantazi, E.6
Folch-Puy, E.7
Abdennebi, H.B.8
Garcia-Gil, F.A.9
Roselló-Catafau, J.10
-
217
-
-
67650649726
-
A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway
-
PMID:19562034
-
Arsham AM, Neufeld TP. A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway. PloS One 2009; 4: e6068; PMID:19562034; http://dx.doi.org/10.1371/journal.pone.0006068
-
(2009)
PloS One
, vol.4
-
-
Arsham, A.M.1
Neufeld, T.P.2
-
218
-
-
56749104288
-
Inclusion-body myositis: Muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer and Parkinson disease brains
-
PMID:18974994
-
Askanas V, Engel WK. Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer and Parkinson disease brains. Acta Neuropathol 2008; 116:583-95; PMID:18974994; http://dx.doi.org/10.1007/s00401-008-0449-0
-
(2008)
Acta Neuropathol
, vol.116
, pp. 583-595
-
-
Askanas, V.1
Engel, W.K.2
-
219
-
-
80655130325
-
Thapsigargin distinguishes membrane fusion in the late stages of endocytosis and autophagy
-
PMID:21921693
-
Ganley IG, Wong PM, Jiang X. Thapsigargin distinguishes membrane fusion in the late stages of endocytosis and autophagy. Autophagy 2011; 7:1397-9; PMID:21921693; http://dx.doi.org/10.4161/auto.7.11.17651
-
(2011)
Autophagy
, vol.7
, pp. 1397-1399
-
-
Ganley, I.G.1
Wong, P.M.2
Jiang, X.3
-
220
-
-
84925775785
-
The membrane peroxin PEX3 induces peroxisome-ubiquitination-linked pexophagy
-
PMID:25007327
-
Yamashita S, Abe K, Tatemichi Y, Fujiki Y. The membrane peroxin PEX3 induces peroxisome-ubiquitination-linked pexophagy. Autophagy 2014; 10:1549-64; PMID:25007327; http://dx.doi.org/10.4161/auto.29329
-
(2014)
Autophagy
, vol.10
, pp. 1549-1564
-
-
Yamashita, S.1
Abe, K.2
Tatemichi, Y.3
Fujiki, Y.4
-
221
-
-
82955207614
-
Cell differentiation: Midbody remnants - Junk or fate factors?
-
PMID:22153165
-
Schink KO, Stenmark H. Cell differentiation: midbody remnants - junk or fate factors? Current Biol: CB 2011; 21:R958-60; PMID:22153165; http://dx. doi.org/10.1016/j.cub.2011.10.035
-
(2011)
Current Biol: CB
, vol.21
, pp. R958-R960
-
-
Schink, K.O.1
Stenmark, H.2
-
222
-
-
79953144994
-
Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death
-
PMID:21173155
-
Grasso D, Ropolo A, Lo Re A, Boggio V, Molejon MI, Iovanna JL, Gonzalez CD, Urrutia R, Vaccaro MI. Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death. J Biol Chem 2011; 286:8308-24; PMID:21173155; http://dx.doi.org/10.1074/jbc.M110.197301
-
(2011)
J Biol Chem
, vol.286
, pp. 8308-8324
-
-
Grasso, D.1
Ropolo, A.2
Lo Re, A.3
Boggio, V.4
Molejon, M.I.5
Iovanna, J.L.6
Gonzalez, C.D.7
Urrutia, R.8
Vaccaro, M.I.9
-
223
-
-
84896714242
-
Dissection of the role of p62/Sqstm1 in activation of Nrf2 during xenophagy
-
PMID:24492006
-
Ishimura R, Tanaka K, Komatsu M. Dissection of the role of p62/Sqstm1 in activation of Nrf2 during xenophagy. FEBS Letters 2014; 588:822-8; PMID:24492006; http://dx.doi.org/10.1016/j. febslet.2014.01.045
-
(2014)
FEBS Letters
, vol.588
, pp. 822-828
-
-
Ishimura, R.1
Tanaka, K.2
Komatsu, M.3
-
224
-
-
84934449988
-
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
-
PMID:26040717
-
Mochida K, Oikawa Y, Kimura Y, Kirisako H, Hirano H, Ohsumi Y, Nakatogawa H. Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus. Nature 2015; 522:359-62; PMID:26040717; http://dx.doi.org/10.1038/nature14506
-
(2015)
Nature
, vol.522
, pp. 359-362
-
-
Mochida, K.1
Oikawa, Y.2
Kimura, Y.3
Kirisako, H.4
Hirano, H.5
Ohsumi, Y.6
Nakatogawa, H.7
-
225
-
-
84938782094
-
A Role for Macro-ER-Phagy in ER Quality Control
-
PMID:26181331
-
Lipatova Z, Segev N. A Role for Macro-ER-Phagy in ER Quality Control. PLoS Genet 2015; 11: e1005390; PMID:26181331
-
(2015)
PLoS Genet
, vol.11
-
-
Lipatova, Z.1
Segev, N.2
-
226
-
-
34250794495
-
XBP1 controls diverse cell type-and condition-specific transcriptional regulatory networks
-
PMID:17612490
-
Acosta-Alvear D, Zhou Y, Blais A, Tsikitis M, Lents NH, Arias C, Lennon CJ, Kluger Y, Dynlacht BD. XBP1 controls diverse cell type-and condition-specific transcriptional regulatory networks. Mol Cell 2007; 27:53-66; PMID:17612490; http://dx.doi.org/10.1016/j.molcel.2007.06.011
-
(2007)
Mol Cell
, vol.27
, pp. 53-66
-
-
Acosta-Alvear, D.1
Zhou, Y.2
Blais, A.3
Tsikitis, M.4
Lents, N.H.5
Arias, C.6
Lennon, C.J.7
Kluger, Y.8
Dynlacht, B.D.9
-
227
-
-
3142658576
-
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
-
PMID:15345222
-
Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, Zhao H, Yu X, Yang L, Tan BK, Rosenwald A, et al. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004; 21:81-93; PMID:15345222; http://dx.doi. org/10.1016/j.immuni.2004.06.010
-
(2004)
Immunity
, vol.21
, pp. 81-93
-
-
Shaffer, A.L.1
Shapiro-Shelef, M.2
Iwakoshi, N.N.3
Lee, A.H.4
Qian, S.B.5
Zhao, H.6
Yu, X.7
Yang, L.8
Tan, B.K.9
Rosenwald, A.10
-
228
-
-
33750440743
-
ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1
-
PMID:16954146
-
Shiraishi H, Okamoto H, Yoshimura A, Yoshida H. ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1. J Cell Sci 2006; 119:3958-66; PMID:16954146; http://dx.doi.org/10.1242/jcs.03160
-
(2006)
J Cell Sci
, vol.119
, pp. 3958-3966
-
-
Shiraishi, H.1
Okamoto, H.2
Yoshimura, A.3
Yoshida, H.4
-
229
-
-
84889889353
-
Nrf2 and Nrf1 signaling and ER stress crosstalk: Implication for proteasomal degradation and autophagy
-
PMID:23800989
-
Digaleh H, Kiaei M, Khodagholi F. Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy. Cell Mol Life Sci 2013; 70:4681-94; PMID:23800989; http://dx.doi.org/10.1007/s00018-013-1409-y
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 4681-4694
-
-
Digaleh, H.1
Kiaei, M.2
Khodagholi, F.3
-
230
-
-
77955947900
-
Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy
-
PMID:20145727
-
Verfaillie T, Salazar M, Velasco G, Agostinis P. Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy. Int J Cell Biol 2010; 2010:930509; PMID:20145727; http://dx.doi.org/10.1155/2010/930509
-
(2010)
Int J Cell Biol
, vol.2010
-
-
Verfaillie, T.1
Salazar, M.2
Velasco, G.3
Agostinis, P.4
-
231
-
-
0036837864
-
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha
-
PMID:12370288
-
Koumenis C, Naczki C, Koritzinsky M, Rastani S, Diehl A, Sonenberg N, Koromilas A, Wouters BG. Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha. Mol Cell Biol 2002; 22:7405-16; PMID:12370288; http://dx.doi.org/10.1128/MCB.22.21.7405-7416.2002
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7405-7416
-
-
Koumenis, C.1
Naczki, C.2
Koritzinsky, M.3
Rastani, S.4
Diehl, A.5
Sonenberg, N.6
Koromilas, A.7
Wouters, B.G.8
-
232
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
PMID:22116877
-
Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011; 334:1081-6; PMID:22116877; http://dx. doi.org/10.1126/science.1209038
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
233
-
-
0037066741
-
The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi
-
PMID:11821395
-
Chen X, Shen J, Prywes R. The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi. J Biol Chem 2002; 277:13045-52; PMID:11821395; http://dx.doi.org/10.1074/jbc. M110636200
-
(2002)
J Biol Chem
, vol.277
, pp. 13045-13052
-
-
Chen, X.1
Shen, J.2
Prywes, R.3
|