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Volumn 34, Issue 21, 2014, Pages 4033-4048

Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; ACTIVATING TRANSCRIPTION FACTOR 6; APOPTOSIS SIGNAL REGULATING KINASE 1; CCAAT ENHANCER BINDING PROTEIN BETA; DEATH ASSOCIATED PROTEIN KINASE; DEATH ASSOCIATED PROTEIN KINASE 1; GAMMA INTERFERON; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 11; MITOGEN ACTIVATED PROTEIN KINASE 12; MITOGEN ACTIVATED PROTEIN KINASE 13; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; UNCLASSIFIED DRUG;

EID: 84907856144     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00397-14     Document Type: Article
Times cited : (63)

References (53)
  • 2
    • 40949118144 scopus 로고    scopus 로고
    • The interferon signaling network and transcription factor C/EBP-beta
    • Li H, Gade P, Xiao W, Kalvakolanu DV. 2007. The interferon signaling network and transcription factor C/EBP-beta. Cell. Mol. Immunol. 4:407-418. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782719/
    • (2007) Cell. Mol. Immunol. , vol.4 , pp. 407-418
    • Li, H.1    Gade, P.2    Xiao, W.3    Kalvakolanu, D.V.4
  • 3
    • 42149123787 scopus 로고    scopus 로고
    • Critical role for transcription factor C/EBP-beta in regulating the expression of deathassociated protein kinase 1
    • Gade P, Roy SK, Li H, Nallar SC, Kalvakolanu DV. 2008. Critical role for transcription factor C/EBP-beta in regulating the expression of deathassociated protein kinase 1. Mol. Cell. Biol. 28:2528-2548. http://dx.doi.org/10.1128/MCB.00784-07.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 2528-2548
    • Gade, P.1    Roy, S.K.2    Li, H.3    Nallar, S.C.4    Kalvakolanu, D.V.5
  • 4
    • 0034725041 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein-beta regulates interferon-induced transcription through a novel element
    • Roy SK, Wachira SJ, Weihua X, Hu J, Kalvakolanu DV. 2000. CCAAT/enhancer-binding protein-beta regulates interferon-induced transcription through a novel element. J. Biol. Chem. 275:12626-12632. http://dx.doi.org/10.1074/jbc.275.17.12626.
    • (2000) J. Biol. Chem. , vol.275 , pp. 12626-12632
    • Roy, S.K.1    Wachira, S.J.2    Weihua, X.3    Hu, J.4    Kalvakolanu, D.V.5
  • 5
    • 33746359639 scopus 로고    scopus 로고
    • The death-associated protein kinases: structure, function, and beyond
    • Bialik S, Kimchi A. 2006. The death-associated protein kinases: structure, function, and beyond. Annu. Rev. Biochem. 75:189-210. http://dx.doi.org/10.1146/annurev.biochem.75.103004.142615.
    • (2006) Annu. Rev. Biochem. , vol.75 , pp. 189-210
    • Bialik, S.1    Kimchi, A.2
  • 6
    • 84862977176 scopus 로고    scopus 로고
    • An IFN-gammastimulated ATF6-C/EBP-beta-signaling pathway critical for the expression of death associated protein kinase 1 and induction of autophagy
    • Gade P, Ramachandran G, Maachani UB, Rizzo MA, Okada T, Prywes R, Cross AS, Mori K, Kalvakolanu DV. 2012. An IFN-gammastimulated ATF6-C/EBP-beta-signaling pathway critical for the expression of death associated protein kinase 1 and induction of autophagy. Proc. Natl. Acad. Sci. U. S. A. 109:10316-10321. http://dx.doi.org/10.1073/pnas.1119273109.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 10316-10321
    • Gade, P.1    Ramachandran, G.2    Maachani, U.B.3    Rizzo, M.A.4    Okada, T.5    Prywes, R.6    Cross, A.S.7    Mori, K.8    Kalvakolanu, D.V.9
  • 7
    • 0347285295 scopus 로고    scopus 로고
    • A trip to the ER: coping with stress
    • Rutkowski DT, Kaufman RJ. 2004. A trip to the ER: coping with stress. Trends Cell. Biol. 14:20-28. http://dx.doi.org/10.1016/j.tcb.2003.11.001.
    • (2004) Trends Cell. Biol. , vol.14 , pp. 20-28
    • Rutkowski, D.T.1    Kaufman, R.J.2
  • 8
    • 0032693671 scopus 로고    scopus 로고
    • Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
    • Haze K, Yoshida H, Yanagi H, Yura T, Mori K. 1999. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol. Biol. Cell 10:3787-3799. http://dx.doi.org/10.1091/mbc.10.11.3787.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 3787-3799
    • Haze, K.1    Yoshida, H.2    Yanagi, H.3    Yura, T.4    Mori, K.5
  • 9
    • 0036069980 scopus 로고    scopus 로고
    • ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals
    • Shen J, Chen X, Hendershot L, Prywes R. 2002. ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev. Cell 3:99-111. http://dx.doi.org/10.1016/S1534-5807(02)00203-4.
    • (2002) Dev. Cell , vol.3 , pp. 99-111
    • Shen, J.1    Chen, X.2    Hendershot, L.3    Prywes, R.4
  • 10
    • 15944408402 scopus 로고    scopus 로고
    • ER stress signaling by regulated proteolysis of ATF6
    • Shen J, Prywes R. 2005. ER stress signaling by regulated proteolysis of ATF6. Methods 35:382-389. http://dx.doi.org/10.1016/j.ymeth.2004.10.011.
    • (2005) Methods , vol.35 , pp. 382-389
    • Shen, J.1    Prywes, R.2
  • 11
    • 9144253936 scopus 로고    scopus 로고
    • The ASK1-MAP kinase cascades in mammalian stress response
    • Matsukawa J, Matsuzawa A, Takeda K, Ichijo H. 2004. The ASK1-MAP kinase cascades in mammalian stress response. J. Biochem. 136:261-265. http://dx.doi.org/10.1093/jb/mvh134.
    • (2004) J. Biochem. , vol.136 , pp. 261-265
    • Matsukawa, J.1    Matsuzawa, A.2    Takeda, K.3    Ichijo, H.4
  • 12
    • 33846603289 scopus 로고    scopus 로고
    • Pathophysiological roles of ASK1-MAP kinase signaling pathways
    • Nagai H, Noguchi T, Takeda K, Ichijo H. 2007. Pathophysiological roles of ASK1-MAP kinase signaling pathways. J. Biochem. Mol. Biol. 40:1-6. http://dx.doi.org/10.5483/BMBRep.2007.40.1.001.
    • (2007) J. Biochem. Mol. Biol. , vol.40 , pp. 1-6
    • Nagai, H.1    Noguchi, T.2    Takeda, K.3    Ichijo, H.4
  • 14
    • 68549083479 scopus 로고    scopus 로고
    • Downregulation of the transcriptional mediator subunit Med1 contributes to the loss of expression of metastasis-associated dapk1 in human cancers and cancer cells
    • Gade P, Singh AK, Roy SK, Reddy SP, Kalvakolanu DV. 2009. Downregulation of the transcriptional mediator subunit Med1 contributes to the loss of expression of metastasis-associated dapk1 in human cancers and cancer cells. Int. J. Cancer 125:1566-1574. http://dx.doi.org/10.1002/ijc.24493.
    • (2009) Int. J. Cancer , vol.125 , pp. 1566-1574
    • Gade, P.1    Singh, A.K.2    Roy, S.K.3    Reddy, S.P.4    Kalvakolanu, D.V.5
  • 16
    • 0030051528 scopus 로고    scopus 로고
    • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ. 1996. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol. 16:1247-1255.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1247-1255
    • Raingeaud, J.1    Whitmarsh, A.J.2    Barrett, T.3    Derijard, B.4    Davis, R.J.5
  • 17
    • 78650115068 scopus 로고    scopus 로고
    • Expression, purification, and characterization of antiplumbagin single-chain variable fragment antibody in Sf9 insect cell
    • Sakamoto S, Taura F, Tsuchihashi R, Putalun W, Kinjo J, Tanaka H, Morimoto S. 2010. Expression, purification, and characterization of antiplumbagin single-chain variable fragment antibody in Sf9 insect cell. Hybridoma 29:481-488. http://dx.doi.org/10.1089/hyb.2010.0052.
    • (2010) Hybridoma , vol.29 , pp. 481-488
    • Sakamoto, S.1    Taura, F.2    Tsuchihashi, R.3    Putalun, W.4    Kinjo, J.5    Tanaka, H.6    Morimoto, S.7
  • 19
    • 49649103791 scopus 로고    scopus 로고
    • Bacillus anthracis spores and lethal toxin induce IL-1beta via functionally distinct signaling pathways
    • Kang TJ, Basu S, Zhang L, Thomas KE, Vogel SN, Baillie L, Cross AS. 2008. Bacillus anthracis spores and lethal toxin induce IL-1beta via functionally distinct signaling pathways. Eur. J. Immunol. 38:1574-1584. http: //dx.doi.org/10.1002/eji.200838141.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 1574-1584
    • Kang, T.J.1    Basu, S.2    Zhang, L.3    Thomas, K.E.4    Vogel, S.N.5    Baillie, L.6    Cross, A.S.7
  • 20
    • 84904982625 scopus 로고    scopus 로고
    • The role of MAPK signalling pathways in the response to endoplasmic reticulum stress
    • Darling NJ, Cook SJ. 2014. The role of MAPK signalling pathways in the response to endoplasmic reticulum stress. Biochim. Biophys. Acta 1843: 2150-2163. http://dx.doi.org/10.1016/j.bbamcr.2014.01.009.
    • (2014) Biochim. Biophys. Acta , vol.1843 , pp. 2150-2163
    • Darling, N.J.1    Cook, S.J.2
  • 21
    • 33645932601 scopus 로고    scopus 로고
    • DAPk protein family and cancer
    • Gozuacik D, Kimchi A. 2006. DAPk protein family and cancer. Autophagy 2:74-79.
    • (2006) Autophagy , vol.2 , pp. 74-79
    • Gozuacik, D.1    Kimchi, A.2
  • 22
    • 77952580741 scopus 로고    scopus 로고
    • The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses
    • Lee YR, Yuan WC, Ho HC, Chen CH, Shih HM, Chen RH. 2010. The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses. EMBO J. 29:1748-1761. http://dx.doi.org /10.1038/emboj.2010.62.
    • (2010) EMBO J , vol.29 , pp. 1748-1761
    • Lee, Y.R.1    Yuan, W.C.2    Ho, H.C.3    Chen, C.H.4    Shih, H.M.5    Chen, R.H.6
  • 23
    • 67650270918 scopus 로고    scopus 로고
    • Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL
    • Zalckvar E, Berissi H, Eisenstein M, Kimchi A. 2009. Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL. Autophagy 5:720-722. http://dx.doi.org/10.4161/auto.5.5.8625.
    • (2009) Autophagy , vol.5 , pp. 720-722
    • Zalckvar, E.1    Berissi, H.2    Eisenstein, M.3    Kimchi, A.4
  • 24
    • 84856951833 scopus 로고    scopus 로고
    • Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase
    • Mor I, Carlessi R, Ast T, Feinstein E, Kimchi A. 2012. Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase. Oncogene 31:683-693. http://dx.doi.org/10.1038/onc.2011.264.
    • (2012) Oncogene , vol.31 , pp. 683-693
    • Mor, I.1    Carlessi, R.2    Ast, T.3    Feinstein, E.4    Kimchi, A.5
  • 25
    • 0036019933 scopus 로고    scopus 로고
    • Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice
    • Matsuzawa A, Nishitoh H, Tobiume K, Takeda K, Ichijo H. 2002. Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice. Antioxid. Redox Signal. 4:415-425. http://dx.doi.org/10.1089/15230860260196218.
    • (2002) Antioxid. Redox Signal. , vol.4 , pp. 415-425
    • Matsuzawa, A.1    Nishitoh, H.2    Tobiume, K.3    Takeda, K.4    Ichijo, H.5
  • 26
    • 0036606540 scopus 로고    scopus 로고
    • ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
    • Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H. 2002. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev. 16:1345-1355. http://dx.doi.org/10.1101/gad.992302.
    • (2002) Genes Dev , vol.16 , pp. 1345-1355
    • Nishitoh, H.1    Matsuzawa, A.2    Tobiume, K.3    Saegusa, K.4    Takeda, K.5    Inoue, K.6    Hori, S.7    Kakizuka, A.8    Ichijo, H.9
  • 27
    • 33748983344 scopus 로고    scopus 로고
    • Topics on the Na_/Ca2_exchanger: responses of Na_/Ca2_exchanger to interferongamma and nitric oxide in cultured microglia
    • Matsuda T, Nagano T, Takemura M, Baba A. 2006. Topics on the Na_/Ca2_exchanger: responses of Na_/Ca2_exchanger to interferongamma and nitric oxide in cultured microglia. J. Pharmacol. Sci. 102:22-http://dx.doi.org/10.1254/jphs.FMJ06002X4.
    • (2006) J. Pharmacol. Sci. , vol.102 , pp. 22-26
    • Matsuda, T.1    Nagano, T.2    Takemura, M.3    Baba, A.4
  • 28
    • 0038034358 scopus 로고    scopus 로고
    • Interferongamma induces reactive oxygen species and endoplasmic reticulum stress at the hepatic apoptosis
    • Watanabe Y, Suzuki O, Haruyama T, Akaike T. 2003. Interferongamma induces reactive oxygen species and endoplasmic reticulum stress at the hepatic apoptosis. J. Cell. Biochem. 89:244-253. http://dx.doi.org/10.1002/jcb.10501.
    • (2003) J. Cell. Biochem. , vol.89 , pp. 244-253
    • Watanabe, Y.1    Suzuki, O.2    Haruyama, T.3    Akaike, T.4
  • 30
    • 0036314984 scopus 로고    scopus 로고
    • Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response
    • Ma Y, Brewer JW, Diehl JA, Hendershot LM. 2002. Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response. J. Mol. Biol. 318:1351-1365. http://dx.doi.org/10.1016/S0022-2836(02)00234-6.
    • (2002) J. Mol. Biol. , vol.318 , pp. 1351-1365
    • Ma, Y.1    Brewer, J.W.2    Diehl, J.A.3    Hendershot, L.M.4
  • 31
    • 0026546365 scopus 로고
    • CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
    • Ron D, Habener JF. 1992. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev. 6:439-453. http://dx.doi.org/10.1101/gad.6.3.439.
    • (1992) Genes Dev , vol.6 , pp. 439-453
    • Ron, D.1    Habener, J.F.2
  • 32
    • 0032493662 scopus 로고    scopus 로고
    • p38 mito genactivated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6.
    • Thuerauf DJ, Arnold ND, Zechner D, Hanford DS, DeMartin KM, McDonough PM, Prywes R, Glembotski CC. 1998. p38 mitogenactivated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor ATF6. J. Biol. Chem. 273:20636- 20643.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20636-20643
    • Thuerauf, D.J.1    Arnold, N.D.2    Zechner, D.3    Hanford, D.S.4    DeMartin, K.M.5    McDonough, P.M.6    Prywes, R.7    Glembotski, C.C.8
  • 33
    • 38449085054 scopus 로고    scopus 로고
    • The interferon-stimulated genes: targets of direct signaling by interferons, double-stranded RNA, and viruses
    • Sen GC, Sarkar SN. 2007. The interferon-stimulated genes: targets of direct signaling by interferons, double-stranded RNA, and viruses. Curr. Top. Microbiol. Immunol. 316:233-250.
    • (2007) Curr. Top. Microbiol. Immunol. , vol.316 , pp. 233-250
    • Sen, G.C.1    Sarkar, S.N.2
  • 34
    • 84880376355 scopus 로고    scopus 로고
    • Emerging regulation and functions of autophagy
    • Boya P, Reggiori F, Codogno P. 2013. Emerging regulation and functions of autophagy. Nat. Cell Biol. 15:713-720. http://dx.doi.org/10.1038/ncb2788.
    • (2013) Nat. Cell Biol. , vol.15 , pp. 713-720
    • Boya, P.1    Reggiori, F.2    Codogno, P.3
  • 35
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine B, Mizushima N, Virgin HW. 2011. Autophagy in immunity and inflammation. Nature 469:323-335. http://dx.doi.org/10.1038/nature09782.
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 37
    • 84873407151 scopus 로고    scopus 로고
    • Non-autophagic roles of autophagy-related proteins
    • Subramani S, Malhotra V. 2013. Non-autophagic roles of autophagy-related proteins. EMBO Rep. 14:143-151. http://dx.doi.org/10.1038/embor.2012.220.
    • (2013) EMBO Rep , vol.14 , pp. 143-151
    • Subramani, S.1    Malhotra, V.2
  • 38
    • 43949145220 scopus 로고    scopus 로고
    • DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing
    • Harrison B, Kraus M, Burch L, Stevens C, Craig A, Gordon-Weeks P, Hupp TR. 2008. DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing. J. Biol. Chem. 283:9999- 10014. http://dx.doi.org/10.1074/jbc.M706040200.
    • (2008) J. Biol. Chem. , vol.283 , pp. 9999-10014
    • Harrison, B.1    Kraus, M.2    Burch, L.3    Stevens, C.4    Craig, A.5    Gordon-Weeks, P.6    Hupp, T.R.7
  • 39
    • 84874005088 scopus 로고    scopus 로고
    • Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling
    • Shiizaki S, Naguro I, Ichijo H. 2013. Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling. Adv. Biol. Regul. 53:135-144. http://dx.doi.org/10.1016/j.jbior.2012.09.006.
    • (2013) Adv. Biol. Regul. , vol.53 , pp. 135-144
    • Shiizaki, S.1    Naguro, I.2    Ichijo, H.3
  • 40
    • 36849043546 scopus 로고    scopus 로고
    • Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1
    • Fujino G, Noguchi T, Matsuzawa A, Yamauchi S, Saitoh M, Takeda K, Ichijo H. 2007. Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1. Mol. Cell. Biol. 27:8152-8163. http://dx.doi.org/10.1128/MCB.00227-07.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 8152-8163
    • Fujino, G.1    Noguchi, T.2    Matsuzawa, A.3    Yamauchi, S.4    Saitoh, M.5    Takeda, K.6    Ichijo, H.7
  • 41
    • 0025736597 scopus 로고
    • A genetic tool used to identify thioredoxin asa mediator of a growth inhibitory signal
    • Deiss LP, Kimchi A. 1991. A genetic tool used to identify thioredoxin asa mediator of a growth inhibitory signal. Science 252:117-120. http://dx.doi.org/10.1126/science.1901424.
    • (1991) Science , vol.252 , pp. 117-120
    • Deiss, L.P.1    Kimchi, A.2
  • 42
    • 71449117666 scopus 로고    scopus 로고
    • Ubiquitin-like sequence in ASK1 plays critical roles in the recognition and stabilization by USP9X and oxidative stress-induced cell death
    • Nagai H, Noguchi T, Homma K, Katagiri K, Takeda K, Matsuzawa A, Ichijo H. 2009. Ubiquitin-like sequence in ASK1 plays critical roles in the recognition and stabilization by USP9X and oxidative stress-induced cell death. Mol. Cell 36:805-818. http://dx.doi.org/10.1016/j.molcel.2009.10.016.
    • (2009) Mol. Cell , vol.36 , pp. 805-818
    • Nagai, H.1    Noguchi, T.2    Homma, K.3    Katagiri, K.4    Takeda, K.5    Matsuzawa, A.6    Ichijo, H.7
  • 43
    • 61849102389 scopus 로고    scopus 로고
    • DAP- kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-X(L) and induction of autophagy
    • Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R, Kimchi A. 2009. DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-X(L) and induction of autophagy. EMBO Rep. 10:285- 292. http://dx.doi.org/10.1038/embor.2008.246.
    • (2009) EMBO Rep , vol.10 , pp. 285-292
    • Zalckvar, E.1    Berissi, H.2    Mizrachy, L.3    Idelchuk, Y.4    Koren, I.5    Eisenstein, M.6    Sabanay, H.7    Pinkas-Kramarski, R.8    Kimchi, A.9
  • 45
    • 57749100267 scopus 로고    scopus 로고
    • MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages
    • Shi CS, Kehrl JH. 2008. MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages. J. Biol. Chem. 283:33175-33182. http://dx.doi.org/10.1074/jbc.M804478200.
    • (2008) J. Biol. Chem. , vol.283 , pp. 33175-33182
    • Shi, C.S.1    Kehrl, J.H.2
  • 49
    • 0345166111 scopus 로고    scopus 로고
    • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
    • Yue Z, Jin S, Yang C, Levine AJ, Heintz N. 2003. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc. Natl. Acad. Sci. U. S. A. 100:15077-15082. http://dx.doi.org/10.1073/pnas.2436255100.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 15077-15082
    • Yue, Z.1    Jin, S.2    Yang, C.3    Levine, A.J.4    Heintz, N.5


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