Quality Control Autophagy Degrades Soluble ERAD-Resistant Conformers of the Misfolded Membrane Protein GnRHR

Molecular Cell

Volumn 54, Issue 1, 2014, Pages 166-179

  Houck, Scott A ^a   Ren, Hong Yu ^a   Madden, Victoria J ^a   Bonner, Jacob N ^a   Conlin, Michael P ^a   Janovick, JoAnn ^b   Conn, P Michael ^b   Cyr, Douglas M ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; BORTEZOMIB; CHLOROQUINE; GONADORELIN RECEPTOR; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P97; ATM PROTEIN; BIOLOGICAL MARKER; CALNEXIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PROTEASOME; SEL1L PROTEIN; TRITON X 100; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL MIGRATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; MOLECULAR INTERACTION; NONHUMAN; PROTEIN CONFORMATION; PROTEIN FOLDING; QUALITY CONTROL; COS 7 CELL LINE; ENDOPLASMIC RETICULUM; LYSOSOME; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN LOCALIZATION; WESTERN BLOTTING;

ANIMALS; AUTOPHAGY; CERCOPITHECUS AETHIOPS; CLASS III PHOSPHATIDYLINOSITOL 3-KINASES; COS CELLS; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; HSP40 HEAT-SHOCK PROTEINS; HUMANS; KINETICS; MODELS, MOLECULAR; MUTATION; PROTEASOME INHIBITORS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN TRANSPORT; PROTEOLYSIS; RECEPTORS, LHRH; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84897986050     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.02.025     Document Type: Article

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