The RUN domain of Rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression

Journal of Biological Chemistry

Volumn 286, Issue 1, 2011, Pages 185-191

  Sun, Qiming ^a   Zhang, Jing ^a   Fan, Weiliang ^a   Wong, Kwun Ngok ^a   Ding, Xiaojun ^b   Chen, She ^b   Zhong, Qing ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; CATALYTIC SUBUNITS; DELETION MUTANTS; DOMAIN-CONTAINING PROTEINS; LIPID KINASE; MOLECULAR MECHANISM; NEGATIVE REGULATORS; PHOSPHATIDYLINOSITOL 3-KINASE; RUBICON;

BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE CLASS 3; PHOSPHOTRANSFERASE; PROTEIN VPS34; RUN DOMAIN PROTEIN AS BECLIN 1 INTERACTING AND CYSTEINE RICH CONTAINING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DELETION MUTANT; ENZYME ACTIVITY; ENZYME INHIBITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

AUTOPHAGY; CLASS III PHOSPHATIDYLINOSITOL 3-KINASES; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; TUMOR SUPPRESSOR PROTEINS;

EID: 78650936005     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.126425     Document Type: Article

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