Activation of transcription factor NF-κB by the adenovirus E3/19K protein requires its ER retention

Journal of Cell Biology

Volumn 132, Issue 4, 1996, Pages 511-522

  Pahl, Heike L ^a   Sester, Martina ^b   Burgert, Hans Gerhard ^b   Baeuerle, Patrick A ^b,c  

^a UNIVERSITY OF FREIBURG   (Germany)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4,5 TRIMETHOXYBENZOIC ACID 8 (DIETHYLAMINO)OCTYL ESTER; ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM ION; CELL MEMBRANE PROTEIN; CYCLOPIAZONIC ACID; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; THAPSIGARGIN; VIRUS PROTEIN;

ADENOVIRUS; ARTICLE; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; ENDOPLASMIC RETICULUM; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPRECIPITATION; MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ADENOVIRUS E3 PROTEINS; ENDOPLASMIC RETICULUM; GENE TRANSFER TECHNIQUES; HELA CELLS; HUMANS; MUTATION; NF-KAPPA B; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS);

ADENOVIRIDAE; EUKARYOTA;

EID: 0030053047     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.132.4.511     Document Type: Article

References (52)

1. Andersson, M., S. Pääbo, T. Nilsson, and P.A. Peterson. 1985. Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance. Cell. 43:215-225.
2. Angel, P , and M. Karin. 1991. The role of jun, fos and the AP-1 complex in cell proliferation and transformation. Biochem. Biophys Acta. 1072:129-157.
3. k gene. Comparison of three H-2K locus alleles Nucleic Acids Res. 12:9473-9487.
4. Baeuerle, P.A , and D, Baltimore. 1988. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor Cell. 53:211-217.
5. Baeuerle, P.A., and T. Henkel. 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12:141-179.
6. Beg, A.A., T.S. Finco, P.V. Nantermet, and A.S. Baldwin Jr 1993. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκB-α: a mechanism for NF-κB activation. Mol. Cell. Biol. 13:3301-3310.
7. Beg, A.A., S.M. Ruben, R.I. Scheinman, S. Haskill, C A Rosen, and A.J. Baldwin. 1992. IκB interacts with the nuclear localization sequences of the subunits of NF-κB: a mechanism for cytoplasmic retention Genes Dev. 6.1899-1913.
8. Bost, K.L., and M.J. Mason. 1995. Thapsigargin and cyclopiazonic acid initiate rapid and dramatic increase of IL-6 mRNA expression and IL-6 secretion in murine peritoneal macrophages. J Immunol. 155:285-296.
9. Burgert, H.-G., and S. Kvist. 1985. An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens. Cell. 41.987-997.
10. Burgert, H.-G., J.L. Maryanski, and S. Kvist. 1987. "E3/19K" protein of adenovirus type 2 inhibits lysis of cytotoxic T lymphocytes by blocking cell surface expression of histocompatibility class I antigens. Proc. Natl. Acad. Sci. USA. 84 1356-1360.
11. 2+ antagonist 8-(N,N diethylamino) octyl 3,4,5-trimethoxybenzoate hydrochloride in smooth and skeletal muscles. Br J. Pharmacol. 53.279-285.
12. Cosson, P., and F. Letourneur. 1994. Coatomer interaction with Di-lysine endoplasmic reticulum retention motifs. Science (Wash. DC). 263:1629-1631.
13. Cox, J.H., J.R. Bennink, and J.W. Yewdell. 1991. Retention of adenovirus E19 glycoprotein in the endoplasmic reticulum is essential to its ability to block antigen presentation. J. Exp. Med. 174:1629-1637.
14. Dahllöf, B., M. Wallin, and S. Kvist. 1991. The endoplasmic retention signal of the E3/19K protein of adenovirus-2 is microtubule binding. J Biol. Chem. 266 1804-1808.
15. Deryckere, F., C. Ebenau-Jehle, W.S.M Wold, and H.-G. Burgert. 1995. Tumor necrosis factor α increases expression of adenovirus E3 proteins. Immunobiol. 193:186-192.
16. Evans, A.S. 1958. Latent adenovirus infections of the human respiratory tract. Am. J. Hyg. 67.562-629.
17. Fox, J., C. Brandt, F. Wassermann, C. Hall, I. Spigland, A. Kogan, and L. Elverback. 1969. The virus watch program: a continuing surveillance of viral infections in metropolitan New York families. Am J. Epidemiol. 89: 25-75
18. Fox, J.P., C E. Hall, and M.K. Cooney. 1977. The Seattle virus watch. VII. Observations of adenovirus infections. Am. J. Epidemiol. 105:362-396.
19. Gabathuler, R., and S. Kvist. 1990. The endoplasmic reticulum retention signal of the E3/19K protein of adenovirus type 2 consists of three separate amino acid segments at the carboxy terminus. J. Cell Biol. 111:1803-1810.
20. Gething, M.-J., and J. Sambrook. 1992. Protein folding in the cell Nature (Lond.). 355:33-44.
21. Ginsberg, H.S., U. Lundholm-Beauchamp, R.L Horstwood, B. Pernis, W.S.M. Wold, R.M. Chanock, and G.A. Prince. 1991. A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia. Proc. Natl. Acad. Sci. USA. 88:1651-1655.
22. 2+-transport ATPase in rat skeletal muscle sarcoplasmic reticulum vesicles. Biochem. Pharmacol. 37:978-981.
23. Graham, F L , and A.J. van der Eb. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 52:456-467.
24. Grilli, M., J.J.-L. Chin, and M.J. Lenardo. 1993. NF-κB and rel - participants in a multiform transcriptional regulatory system Int. Rev. Cytol. 143:1-62.
25. Henkel, T., T. Machleidt, I. Alkalay, Y. Ben-Neriah, M. Kronke, and P.A. Baeuerle 1993. Rapid proteolytic degradation of IκB-α induced by stimulation of cells with phorbol ester, cytokines and liposaccharides is a necessary step in the activation of NF-κB. Nature (Lond.). 365:182-184.
26. Hérissé, J., G. Courtois, and F. Galibert. 1980. Nucleotide sequence of the EcoRI D fragment of adenovirus 2 genome. Nucleic Acids Res 8:2173-2192.
27. Higuchi, R., B. Krummel, and R K. Saiki. 1988. A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions Nucleic Acids Res. 16:7351-7367.
28. Israel, A., O. LeBail, D Hatat, J. Piette, M. Kieran, F Logeat, D. Wallach, M. Fellous, and P. Kourilsky. 1989. TNF stimulates expression of mouse MHC class 1 genes by inducing an NF-κB-like enhancer binding activity which displaces constitutive factors. EMBO (Eur. Mol. Biol. Organ.) J. 8: 3793-3800.
29. Jackson, M.R., T. Nilsson, and P.A. Peterson. 1990. Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum. EMBO (Eur. Mol. Biol. Organ.) J. 9:3153-3162.
30. Jackson, M.R., T. Nilsson, and P.A. Peterson. 1993. Retrieval of transmembrane proteins to the endoplasmic reticulum. J. Cell Biol. 121:317-333.
31. Körner, H., U. Fritzsche, and H.-G. Burgert. 1992. Tumor necrosis factor α stimulates expression of adenovirus early region 3 proteins: implications for viral persistence. Proc. Natl Acad. Sci. USA. 89:11857-11861.
32. d gene. EMBO (Eur. Mol. Biol. Organ.) J. 2:245-254.
33. Letourneur, F , E.C. Gaynor, S. Hennecke, C. Démollière, R Duden, S. Emr, H. Riezman, and P. Cosson. 1994. Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum. Cell 79: 1199-1207.
34. Libermann, T.A., and D. Baltimore. 1990. Activation of interleukin-6 gene expression through the NF-κB transcription factor. Mol. Cell Biol. 10: 2327-2334.
35. Lucocq, J.M., G. Warren, and J. Pryde. 1991. Okadaic acid induces Golgi apparatus fragmentation and arrest of intracellular transport. J. Cell Sci 100:753-759.
36. 2+ antagonist, 8-(N,N diethylamino) octyl 3,4,5-trimethoxybenzoate hydrochloride (TMB-8): studies in smooth muscles. Eur. J. Pharmacol. 27:25-35.
37. Meyer, M., W.H. Caselmann, V. Schluter, R. Schreck, P.H. Hofschneider, and P.A. Baeuerle. 1992. Hepatitis B virus transactivator MHBst: activation of NF-κB, selective inhibition by antioxidants and integral membrane localization. EMBO (Eur. Mol. Biol. Organ.) J. 11:2991-3001.
38. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO (Eur. Mol. Biol. Organ.) J. 12:2005-2015
39. Owen, M J., A M. Kissonerghis, and H.F. Lodish. 1980. Biosynthesis of HLA-A and HLA-B antigens in vivo. J. Biol Chem. 255:9678-9684.
40. Pahl, H.L., and P.A. Baeuerle. 1995. Expression of influenza hemagglutinin activates transcription factor NF-κB. J. Virol. 69:1480-1484.
41. Pahl, H.L., and P.A. Baeuerle. 1995. A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-κB. EMBO (Eur. Mol. Biol. Organ.) J. 14:2580-2588.
42. Pahl, H.L., T.C. Burns, and D.G. Tenen. 1991. Optimization of transient transfection into human myeloid cell lines using a luciferase reporter gene. Exp. Hematol. 19.1038-1041.
43. b gene expression in metastatic tumor cells. J. Exp. Med. 177:1651-1662.
44. Schmidt, K.N., E.B.-M. Traenckner, and P.A. Baeuerle. 1995. Induction of oxidative stress by okadaic acid is required for activation of transcription factor NF-κB. J. Biol. Chem. 270:27136-27142.
45. Sester, M., and H.-G. Burgert. 1994. Conserved cysteine residues within the E3/19K protein of adenovirus type 2 are essential for binding to major histocompatibility complex antigens. J. Virol. 68:5423-5432.
46. Sun, S.-C , P.A. Ganchi, C. Béraud, D.W Ballard, and W.C. Greene. 1994. Autoregulation of the NF-κB transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs. Proc. Natl. Acad. Sci. USA. 87:1346-1350.
47. 2+-ATPase. Proc Natl Acad Sci USA. 87:2466-2470.
48. Tong-Starksen, S.E., P.A. Luciw, and B.M. Peterlin. 1989. Signalling through T lymphocyte surface proteins, TCR/CD3 and CD28, activates the HIV-1 long terminal repeat. J Immunol. 142:702-707.
49. Traenckner, E.B.-M., H.L. Pahl, T Henkel, K.N. Schmidt, S. Wilk, and P.A. Baeuerle. 1995. Phosphorylation of human IκB-α on serine 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli EMBO (Eur. Mol Biol. Organ) J 14:2876-2883.
50. Traenckner, E.B.-M., S. Wilk, and P.A Baeuerle 1994. A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB. EMBO (Eur Mol. Biol. Organ.) J 13:5433-5441
51. Williams, J.L., J. Garcia, D. Harrich, L. Pearson, F. Wu, and R. Gaynor. 1990 Lymphoid specific gene expression of the adenovirus early region 3 promoter is mediated by NF-κB binding motifs. EMBO (Eur. Mol. Biol. Organ.) J. 9.4435-4442
52. Zabel, U., T. Henkel, M.S. Silva, and P.A. Baeuerle 1993 Nuclear uptake control of NF-κB by MAD-3, an IκB protein present in the nucleus. EMBO (Eur. Mol. Biol. Organ) J. 12:201-211.