Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 13, 1999, Pages 7421-7426

  Biggs III, William H ^a,d   Meisenhelder, Jill ^c   Hunter, Tony ^c   Cavenee, Webster K ^a,b   Arden, Karen C ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d LUDWIG INSTITUTE FOR CANCER RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; GENETIC ANALYSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL NUCLEUS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; MUTATION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS;

EID: 0033595011     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.13.7421     Document Type: Article

References (47)

1. Kaufmann, E. & Knöchel, W. (1996) Mech. Dev. 57, 3-20.
2. Hromas, R. & Costa, R. (1995) Crit. Rev. Oncol. Hematol. 20, 129-140.
3. Vogt, P. K., Li, J. & Freyaldenhoven, B. S. (1997) Virology 238, 1-7.
4. Barr, F. G. (1997) Curr. Top. Microbiol. Immunol. 220, 113-129.
5. Hillion, J., Le Coniat, M., Jonveaux, P., Berger, R. & Bernard, O. A. (1997) Blood 90, 3714-3719.
6. Borkhardt, A., Repp, R., Haas, O. A., Leis, T., Harbott, J., Kreuder, J., Hammermann, J., Henn, T. & Lampert, F. (1997) Oncogene 14, 195-202.
7. Arden, K. C., Anderson, M. J., Finckenstein, F. G., Czekay, S. & Cavenee, W. K. (1996) Genes Chromosomes Cancer 16, 254-260.
8. Kaffman, A., Rank, N. M., O'Neill, E. M., Huang, L. S. & O'Shea, E. K. (1998) Nature (London) 396, 482-486.
9. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A. & Struhl, K. (1998) in Current Protocols, ed. Chanda, V. B. (Wiley, New York), pp. 15.1.1-15.1.5.
10. Knudsen, K. E., Arden, K. C. & Cavenee, W. K. (1998) J. Biol. Chem. 273, 20213-20222.
11. Franke, T. F., Yang, S. I., Chan, T. O., Datta, K., Kazlauskas, A., Morrison, D. K., Kaplan, D. R. & Tsichlis, P. N. (1995) Cell 81, 727-736.
12. van der Geer, P., Luo, K., Sefton, B. M. & Hunter, T. (1994) in Cell Biology: A Laboratory Manual, ed. Celis, J. E. (Academic, San Diego), pp. 422-446.
13. Alessi, D. R., Caudwell, F. B., Andjelkovic, M., Hemmings, B. A. & Cohen, P. (1996) FEBS Lett. 399, 333-338.
14. Wolff, B., Sanglier, J. J. & Wang, Y. (1997) Chem. Biol. 4, 139-147.
15. Kudo, N., Wolff, B., Sekimoto, T., Schreiner, E. P., Yoneda, Y., Yanagida, M., Horinouchi, S. & Yoshida, M. (1998) Exp. Cell Res. 242, 540-547.
16. Nishi, K., Yoshida, M., Fujiwara, D., Nishikawa, M., Horinouchi, S. & Beppu, T. (1994) J. Biol. Chem. 269, 6320-6324.
17. Ogg, S., Paradis, S., Gottlieb, S., Patterson, G. I., Lee, L., Tissenbaum, H. A. & Ruvkun, G. (1997) Nature (London) 389, 994-999.
18. Lin, K., Dorman, J. B., Rodan, A. & Kenyon, C. (1997) Science 278, 1319-1322.
19. Paradis, S. & Ruvkun, G. (1998) Genes Dev. 12, 2488-2498.
20. Carpenter, C. L. & Cantley, L. C. (1996) Curr. Opin. Cell Biol. 8, 153-158.
21. Hara, K., Yonezawa, K., Sakaue, H., Ando, A., Kotani, K., Kitamura, T., Kitamura, Y., Ueda, H., Stephens, L., Jackson, T. R., et al. (1994) Proc. Natl. Acad. Sci. USA 91, 7415-7419.
22. Jimenez, C., Jones, D. R., Rodriguez-Viciana, P., Gonzalez-Garcia, A., Leonardo, E., Wennström, S., von Kobbe, C., Toran, J. L., Calvo, V., Copin, S. G., et al. (1998) EMBO J. 17, 743-753.
23. Qian, X. & Costa, R. H. (1995) Nucleic Acids Res. 23, 1184-1191.
24. Taagepera, S., McDonald, D., Loeb, J. E., Whitaker, L. L., McElroy, A. K., Wang, J. Y. & Hope, T. J. (1998) Proc. Natl. Acad. Sci. USA 95, 7457-7462.
25. Kim, F. J., Beeche, A. A., Hunter, J. J., Chin, D. J. & Hope, T. J. (1996) Mol. Cell. Biol. 16, 5147-5155.
26. Montminy, M. (1997) Annu. Rev. Biochem. 66, 807-822.
27. Karin, M. & Hunter, T. (1995) Curr. Biol. 5, 747-757.
28. Alessi, D. R. & Cohen, P. (1998) Curr. Opin. Genet. Dev. 8, 55-62.
29. Coffer, P. J., Jin, J. & Woodgett, J. R. (1998) Biochem. J. 335, 1-13.
30. Downward, J. (1998) Curr. Opin. Cell Biol. 10, 262-267.
31. Blume-Jensen, P., Janknecht, R. & Hunter, T. (1998) Curr. Biol. 8, 779-782.
32. Cardone, M. H., Roy, N., Stennicke, H. R., Savlesen, G. S., Franke, T. F., Stanbridge, E., Frisch, S. & Reed, J. C. (1998) Science 282, 1318-1321.
33. Cross, D. A., Alessi, D. R., Cohen, P., Andjelkovich, M. & Hemmings, B. A. (1995) Nature (London) 378, 785-789.
34. Reif, K., Burgering, B. M. & Cantrell, D. A. (1997) J. Biol. Chem. 272, 14426-14433.
35. Anderson, M. J., Viars, C. S., Czekay, S., Cavenee, W. K. & Arden, K. C. (1998) Genomics 47, 187-199.
36. Toker, A. & Cantley, L. C. (1997) Nature (London) 387, 673-676.
37. Konishi, H., Kuroda, S., Tanaka, M., Matsuzaki, H., Ono, Y., Kameyama, K., Haga, T. & Kikkawa, U. (1995) Biochem. Biophys. Res. Commun. 216, 526-534.
38. Cheng, J. Q., Godwin, A. K., Bellacosa, A., Taguchi, T., Franke, T. F., Hamilton, T. C., Tsichlis, P. N. & Testa, J. R. (1992) Proc. Natl. Acad. Sci. USA 89, 9267-9271.
39. Coffer, P. J. & Woodgett, J. R. (1991) Eur. J. Biochem. 201, 475-481.
40. Jones, P. F., Jakubowicz, T., Pitossi, F. J., Maurer, F. & Hemmings, B. A. (1991) Proc. Natl. Acad. Sci. USA 88, 4171-4175.
41. Bellacosa, A., Testa, J. R., Staal, S. P. & Tsichlis, P. N. (1991) Science 254, 274-277.
42. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y. & Greenberg, M. E. (1997) Cell 91, 231-241.
43. Liu, A. X., Testa, J. R., Hamilton, T. C., Jove, R., Nicosia, S. V. & Cheng, J. Q. (1998) Cancer Res. 58, 2973-2977.
44. Bellacosa, A., de Feo, D., Godwin, A. K., Bell, D. W., Cheng, J. Q., Altomar, D. A., Wan, M., Dubeau, L., Scambia, G., Masciollo, V., et al. (1995) Int. J. Cancer 64, 280-285.
45. Beals, C. R., Sheridan, C. M., Turck, C. W., Gardner, P. & Crabtree, G. R. (1997) Science 275, 1930-1934.
46. Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J. & Greenberg, M. E. (1999) Cell 96, 857-868.
47. Kops, G. J., de Ruiter, N. D., De Vries-Smits, A. M., Powell, D. R., Bos, J. L. & Burgering, B. M. (1999) Nature (London) 398, 630-634.