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Volumn 41, Issue 16, 2013, Pages 7683-7699

The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; PHOSPHOTRANSFERASE; PROTEIN GCN2; PROTEIN PERK; UNCLASSIFIED DRUG; AMINO ACID; EIF2AK4 PROTEIN, MOUSE; HEAT SHOCK PROTEIN; INITIATION FACTOR 2; PERK KINASE; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, MOUSE;

EID: 84885455062     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt563     Document Type: Article
Times cited : (840)

References (69)
  • 3
    • 32544446451 scopus 로고    scopus 로고
    • Coping with stress: EIF2 kinases and translational control
    • Wek,R.C., Jiang,H.Y. and Anthony,T.G. (2006) Coping with stress: eIF2 kinases and translational control. Biochem. Soc. Trans., 34, 7-11.
    • (2006) Biochem. Soc. Trans. , vol.34 , pp. 7-11
    • Wek, R.C.1    Jiang, H.Y.2    Anthony, T.G.3
  • 4
    • 0033590451 scopus 로고    scopus 로고
    • Protein translation and folding are coupled by an endoplasmic-reticulum- resident kinase [published erratum appears in Nature 1999 Mar 4;398(6722):90]
    • Harding,H.P., Zhang,Y. and Ron,D. (1999) Protein translation and folding are coupled by an endoplasmic-reticulum- resident kinase [published erratum appears in Nature 1999 Mar 4;398(6722):90]. Nature, 397, 271-274.
    • (1999) Nature , vol.397 , pp. 271-274
    • Harding, H.P.1    Zhang, Y.2    Ron, D.3
  • 5
    • 0002470681 scopus 로고    scopus 로고
    • Mechanism and regulation of intiator methionyl-tRNA binding to ribosomes
    • In: Sonenberg,N., Hershey,J.W.B. and Mathews,M.B. (eds), Translational Control of Gene Expression
    • Hinnebusch,A.G. (2000) Mechanism and regulation of intiator methionyl-tRNA binding to ribosomes. In: Sonenberg,N., Hershey,J.W.B. and Mathews,M.B. (eds), Translational Control of Gene Expression. CSHL Pres, Cold Spring Harbor, NY, pp. 185-243.
    • (2000) CSHL Pres, Cold Spring Harbor, NY , pp. 185-243
    • Hinnebusch, A.G.1
  • 6
    • 0033962298 scopus 로고    scopus 로고
    • A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha
    • Sood,R., Porter,A.C., Olsen,D.A., Cavener,D.R. and Wek,R.C. (2000) A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha. Genetics, 154, 787-801.
    • (2000) Genetics , vol.154 , pp. 787-801
    • Sood, R.1    Porter, A.C.2    Olsen, D.A.3    Cavener, D.R.4    Wek, R.C.5
  • 8
    • 35848935017 scopus 로고    scopus 로고
    • Translational control and the unfolded protein response
    • Wek,R.C. and Cavener,D.R. (2007) Translational control and the unfolded protein response. Antioxid. Redox Signal., 9, 2357-2371.
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 2357-2371
    • Wek, R.C.1    Cavener, D.R.2
  • 10
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding,H.P., Novoa,I.I., Zhang,Y., Zeng,H., Wek,R., Schapira,M. and Ron,D. (2000) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell, 6, 1099-1108.
    • (2000) Mol. Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6    Ron, D.7
  • 11
    • 5444264022 scopus 로고    scopus 로고
    • Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
    • Lu,P.D., Harding,H.P. and Ron,D. (2004) Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response. J. Cell. Biol., 167, 27-33.
    • (2004) J. Cell. Biol. , vol.167 , pp. 27-33
    • Lu, P.D.1    Harding, H.P.2    Ron, D.3
  • 12
    • 3843117589 scopus 로고    scopus 로고
    • Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
    • Vattem,K.M. and Wek,R.C. (2004) Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc. Natl Acad. Sci. USA, 101, 11269-11274.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 11269-11274
    • Vattem, K.M.1    Wek, R.C.2
  • 13
    • 0037025396 scopus 로고    scopus 로고
    • ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene
    • Siu,F., Bain,P.J., LeBlanc-Chaffin,R., Chen,H. and Kilberg,M.S. (2002) ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene. J. Biol. Chem., 277, 24120-24127.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24120-24127
    • Siu, F.1    Bain, P.J.2    Leblanc-Chaffin, R.3    Chen, H.4    Kilberg, M.S.5
  • 14
    • 1242272070 scopus 로고    scopus 로고
    • Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation
    • Averous,J., Bruhat,A., Jousse,C., Carraro,V., Thiel,G. and Fafournoux,P. (2004) Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation. J. Biol. Chem., 279, 5288-5297.
    • (2004) J. Biol. Chem. , vol.279 , pp. 5288-5297
    • Averous, J.1    Bruhat, A.2    Jousse, C.3    Carraro, V.4    Thiel, G.5    Fafournoux, P.6
  • 16
    • 0037073799 scopus 로고    scopus 로고
    • Differences in the molecular mechanisms involved in the transcriptional activation of the CHOP and asparagine synthetase genes in response to amino acid deprivation or activation of the unfolded protein response
    • Bruhat,A., Averous,J., Carraro,V., Zhong,C., Reimold,A.M., Kilberg,M.S. and Fafournoux,P. (2002) Differences in the molecular mechanisms involved in the transcriptional activation of the CHOP and asparagine synthetase genes in response to amino acid deprivation or activation of the unfolded protein response. J. Biol. Chem., 277, 48107-48114.
    • (2002) J. Biol. Chem. , vol.277 , pp. 48107-48114
    • Bruhat, A.1    Averous, J.2    Carraro, V.3    Zhong, C.4    Reimold, A.M.5    Kilberg, M.S.6    Fafournoux, P.7
  • 17
    • 72049124015 scopus 로고    scopus 로고
    • ATF4-dependent transcription mediates signaling of amino acid limitation
    • Kilberg,M.S., Shan,J. and Su,N. (2009) ATF4-dependent transcription mediates signaling of amino acid limitation. Trends Endocrinol. Metab., 20, 436-443.
    • (2009) Trends Endocrinol. Metab. , vol.20 , pp. 436-443
    • Kilberg, M.S.1    Shan, J.2    Su, N.3
  • 18
    • 58049203872 scopus 로고    scopus 로고
    • C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene
    • Su,N. and Kilberg,M.S. (2008) C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene. J. Biol. Chem., 283, 35106-35117.
    • (2008) J. Biol. Chem. , vol.283 , pp. 35106-35117
    • Su, N.1    Kilberg, M.S.2
  • 19
    • 10944269132 scopus 로고    scopus 로고
    • Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized histone acetylation
    • Chen,H., Pan,Y.X., Dudenhausen,E.E. and Kilberg,M.S. (2004) Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized histone acetylation. J. Biol. Chem., 279, 50829-50839.
    • (2004) J. Biol. Chem. , vol.279 , pp. 50829-50839
    • Chen, H.1    Pan, Y.X.2    Dudenhausen, E.E.3    Kilberg, M.S.4
  • 22
    • 74849136799 scopus 로고    scopus 로고
    • Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia
    • Rzymski,T., Milani,M., Singleton,D.C. and Harris,A.L. (2009) Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia. Cell Cycle, 8, 3838-3847.
    • (2009) Cell Cycle , vol.8 , pp. 3838-3847
    • Rzymski, T.1    Milani, M.2    Singleton, D.C.3    Harris, A.L.4
  • 24
    • 0032940099 scopus 로고    scopus 로고
    • CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI
    • Sok,J., Wang,X.Z., Batchvarova,N., Kuroda,M., Harding,H. and Ron,D. (1999) CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI. Mol. Cell. Biol., 19, 495-504.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 495-504
    • Sok, J.1    Wang, X.Z.2    Batchvarova, N.3    Kuroda, M.4    Harding, H.5    Ron, D.6
  • 25
    • 34548188741 scopus 로고    scopus 로고
    • Selfeating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri,M.C., Zalckvar,E., Kimchi,A. and Kroemer,G. (2007) Selfeating and self-killing: crosstalk between autophagy and apoptosis. Nat. Rev. Mol. Cell Biol., 8, 741-752.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 26
    • 36249025723 scopus 로고    scopus 로고
    • Autophagy: Process and function
    • Mizushima,N. (2007) Autophagy: process and function. Genes Dev., 21, 2861-2873.
    • (2007) Genes Dev. , vol.21 , pp. 2861-2873
    • Mizushima, N.1
  • 27
    • 81055144784 scopus 로고    scopus 로고
    • Autophagy: Renovation of cells and tissues
    • Mizushima,N. and Komatsu,M. (2011) Autophagy: renovation of cells and tissues. Cell, 147, 728-741.
    • (2011) Cell , vol.147 , pp. 728-741
    • Mizushima, N.1    Komatsu, M.2
  • 28
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine,B. and Kroemer,G. (2008) Autophagy in the pathogenesis of disease. Cell, 132, 27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 29
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima,N., Levine,B., Cuervo,A.M. and Klionsky,D.J. (2008) Autophagy fights disease through cellular self-digestion. Nature, 451, 1069-1075.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 31
    • 43249109174 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress responses
    • Schroder,M. (2008) Endoplasmic reticulum stress responses. Cell Mol. Life Sci., 65, 862-894.
    • (2008) Cell Mol. Life Sci. , vol.65 , pp. 862-894
    • Schroder, M.1
  • 32
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • Kroemer,G., Marino,G. and Levine,B. (2010) Autophagy and the integrated stress response. Mol. Cell., 40, 280-293.
    • (2010) Mol. Cell. , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 38
    • 79952355107 scopus 로고    scopus 로고
    • Selective autophagy mediated by autophagic adapter proteins
    • Johansen,T. and Lamark,T. (2011) Selective autophagy mediated by autophagic adapter proteins. Autophagy, 7, 279-296.
    • (2011) Autophagy , vol.7 , pp. 279-296
    • Johansen, T.1    Lamark, T.2
  • 39
    • 58449089596 scopus 로고    scopus 로고
    • Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2- dependent and GCN2-independent pathways
    • Deval,C., Chaveroux,C., Maurin,A.C., Cherasse,Y., Parry,L., Carraro,V., Milenkovic,D., Ferrara,M., Bruhat,A., Jousse,C. et al. (2009) Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2- dependent and GCN2-independent pathways. FEBS J., 276, 707-718.
    • (2009) FEBS J. , vol.276 , pp. 707-718
    • Deval, C.1    Chaveroux, C.2    Maurin, A.C.3    Cherasse, Y.4    Parry, L.5    Carraro, V.6    Milenkovic, D.7    Ferrara, M.8    Bruhat, A.9    Jousse, C.10
  • 40
    • 4444220680 scopus 로고    scopus 로고
    • Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation
    • Seibenhener,M.L., Babu,J.R., Geetha,T., Wong,H.C., Krishna,N.R. and Wooten,M.W. (2004) Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. Mol. Cell. Biol., 24, 8055-8068.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 8055-8068
    • Seibenhener, M.L.1    Babu, J.R.2    Geetha, T.3    Wong, H.C.4    Krishna, N.R.5    Wooten, M.W.6
  • 41
    • 27944504351 scopus 로고    scopus 로고
    • P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    • Bjorkoy,G., Lamark,T., Brech,A., Outzen,H., Perander,M., Overvatn,A., Stenmark,H. and Johansen,T. (2005) p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell. Biol., 171, 603-614.
    • (2005) J. Cell. Biol. , vol.171 , pp. 603-614
    • Bjorkoy, G.1    Lamark, T.2    Brech, A.3    Outzen, H.4    Perander, M.5    Overvatn, A.6    Stenmark, H.7    Johansen, T.8
  • 44
    • 0024852591 scopus 로고
    • Transcriptional activity of the human thymidine kinase gene determined by a method using the polymerase chain reaction and an intron-specific probe
    • Lipson,K.E. and Baserga,R. (1989) Transcriptional activity of the human thymidine kinase gene determined by a method using the polymerase chain reaction and an intron-specific probe. Proc. Natl Acad. Sci. USA, 86, 9774-9777.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 9774-9777
    • Lipson, K.E.1    Baserga, R.2
  • 45
    • 0033830234 scopus 로고    scopus 로고
    • Amino acids control mammalian gene transcription: Activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter
    • Bruhat,A., Jousse,C., Carraro,V., Reimold,A.M., Ferrara,M. and Fafournoux,P. (2000) Amino acids control mammalian gene transcription: activating transcription factor 2 is essential for the amino acid responsiveness of the CHOP promoter. Mol. Cell. Biol., 20, 7192-7204.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7192-7204
    • Bruhat, A.1    Jousse, C.2    Carraro, V.3    Reimold, A.M.4    Ferrara, M.5    Fafournoux, P.6
  • 46
    • 0026546365 scopus 로고
    • CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant- negative inhibitor of gene transcription
    • Ron,D. and Habener,J.F. (1992) CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant- negative inhibitor of gene transcription. Genes Dev., 6, 439-453.
    • (1992) Genes Dev. , vol.6 , pp. 439-453
    • Ron, D.1    Habener, J.F.2
  • 47
    • 0034109871 scopus 로고    scopus 로고
    • Molecular interactions involved in the transactivation of the human T-cell leukemia virus type 1 promoter mediated by Tax and CREB-2 (ATF-4)
    • Gachon,F., Thebault,S., Peleraux,A., Devaux,C. and Mesnard,J.M. (2000) Molecular interactions involved in the transactivation of the human T-cell leukemia virus type 1 promoter mediated by Tax and CREB-2 (ATF-4). Mol. Cell. Biol., 20, 3470-3481.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3470-3481
    • Gachon, F.1    Thebault, S.2    Peleraux, A.3    Devaux, C.4    Mesnard, J.M.5
  • 49
    • 0017697151 scopus 로고
    • Induction of autophagy by amino-acid deprivation in perfused rat liver
    • Mortimore,G.E. and Schworer,C.M. (1977) Induction of autophagy by amino-acid deprivation in perfused rat liver. Nature, 270, 174-176.
    • (1977) Nature , vol.270 , pp. 174-176
    • Mortimore, G.E.1    Schworer, C.M.2
  • 51
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima,N., Yoshimori,T. and Levine,B. (2010) Methods in mammalian autophagy research. Cell, 140, 313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 53
    • 17144417669 scopus 로고    scopus 로고
    • TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
    • Ohoka,N., Yoshii,S., Hattori,T., Onozaki,K. and Hayashi,H. (2005) TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. EMBO J., 24, 1243-1255.
    • (2005) EMBO J. , vol.24 , pp. 1243-1255
    • Ohoka, N.1    Yoshii, S.2    Hattori, T.3    Onozaki, K.4    Hayashi, H.5
  • 54
    • 0030814110 scopus 로고    scopus 로고
    • Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post- transcriptional levels
    • Bruhat,A., Jousse,C., Wang,X.Z., Ron,D., Ferrara,M. and Fafournoux,P. (1997) Amino acid limitation induces expression of CHOP, a CCAAT/enhancer binding protein-related gene, at both transcriptional and post- transcriptional levels. J. Biol. Chem., 272, 17588-17593.
    • (1997) J. Biol. Chem. , vol.272 , pp. 17588-17593
    • Bruhat, A.1    Jousse, C.2    Wang, X.Z.3    Ron, D.4    Ferrara, M.5    Fafournoux, P.6
  • 56
    • 0029928173 scopus 로고    scopus 로고
    • Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element
    • Ubeda,M., Wang,X.Z., Zinszner,H., Wu,I., Habener,J.F. and Ron,D. (1996) Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element. Mol. Cell. Biol., 16, 1479-1489.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1479-1489
    • Ubeda, M.1    Wang, X.Z.2    Zinszner, H.3    Wu, I.4    Habener, J.F.5    Ron, D.6
  • 57
    • 78650961487 scopus 로고    scopus 로고
    • Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro
    • Ke,P.Y. and Chen,S.S. (2011) Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro. J. Clin. Invest., 121, 37-56.
    • (2011) J. Clin. Invest. , vol.121 , pp. 37-56
    • Ke, P.Y.1    Chen, S.S.2
  • 58
    • 77956172813 scopus 로고    scopus 로고
    • Physiological role of autophagy as an intracellular recycling system: With an emphasis on nutrient metabolism
    • Kuma,A. and Mizushima,N. (2010) Physiological role of autophagy as an intracellular recycling system: with an emphasis on nutrient metabolism. Semin. Cell. Dev. Biol., 21, 683-690.
    • (2010) Semin. Cell. Dev. Biol. , vol.21 , pp. 683-690
    • Kuma, A.1    Mizushima, N.2
  • 60
    • 77954366843 scopus 로고    scopus 로고
    • Molecular symbiosis of CHOP and C/EBP beta isoform LIP contributes to endoplasmic reticulum stress-induced apoptosis
    • Chiribau,C.B., Gaccioli,F., Huang,C.C., Yuan,C.L. and Hatzoglou,M. (2010) Molecular symbiosis of CHOP and C/EBP beta isoform LIP contributes to endoplasmic reticulum stress-induced apoptosis. Mol. Cell. Biol., 30, 3722-3731.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 3722-3731
    • Chiribau, C.B.1    Gaccioli, F.2    Huang, C.C.3    Yuan, C.L.4    Hatzoglou, M.5
  • 62
    • 0028899789 scopus 로고
    • Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
    • Blommaart,E.F., Luiken,J.J., Blommaart,P.J., van Woerkom,G.M. and Meijer,A.J. (1995) Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J. Biol. Chem., 270, 2320-2326.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2320-2326
    • Blommaart, E.F.1    Luiken, J.J.2    Blommaart, P.J.3    Van Woerkom, G.M.4    Meijer, A.J.5
  • 64
    • 84865302358 scopus 로고    scopus 로고
    • Mechanisms and regulation of autophagosome formation
    • Kraft,C. and Martens,S. (2012) Mechanisms and regulation of autophagosome formation. Curr. Opin. Cell. Biol., 24, 496-501.
    • (2012) Curr. Opin. Cell. Biol. , vol.24 , pp. 496-501
    • Kraft, C.1    Martens, S.2
  • 66
    • 36448968532 scopus 로고    scopus 로고
    • FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells
    • Zhao,J., Brault,J.J., Schild,A., Cao,P., Sandri,M., Schiaffino,S., Lecker,S.H. and Goldberg,A.L. (2007) FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab., 6, 472-483.
    • (2007) Cell Metab. , vol.6 , pp. 472-483
    • Zhao, J.1    Brault, J.J.2    Schild, A.3    Cao, P.4    Sandri, M.5    Schiaffino, S.6    Lecker, S.H.7    Goldberg, A.L.8
  • 67
    • 0025728532 scopus 로고
    • A quantitative model for translational control of the GCN4 gene of Saccharomyces cerevisiae
    • Abastado,J.P., Miller,P.F. and Hinnebusch,A.G. (1991) A quantitative model for translational control of the GCN4 gene of Saccharomyces cerevisiae. New Biol., 3, 511-524.
    • (1991) New Biol. , vol.3 , pp. 511-524
    • Abastado, J.P.1    Miller, P.F.2    Hinnebusch, A.G.3
  • 68
    • 34548299555 scopus 로고    scopus 로고
    • Linking of autophagy to ubiquitinproteasome system is important for the regulation of endoplasmic reticulum stress and cell viability
    • Ding,W.X., Ni,H.M., Gao,W., Yoshimori,T., Stolz,D.B., Ron,D. and Yin,X.M. (2007) Linking of autophagy to ubiquitinproteasome system is important for the regulation of endoplasmic reticulum stress and cell viability. Am. J. Pathol., 171, 513-524.
    • (2007) Am. J. Pathol. , vol.171 , pp. 513-524
    • Ding, W.X.1    Ni, H.M.2    Gao, W.3    Yoshimori, T.4    Stolz, D.B.5    Ron, D.6    Yin, X.M.7
  • 69
    • 79959415069 scopus 로고    scopus 로고
    • Biogenesis and cargo selectivity of autophagosomes
    • Weidberg,H., Shvets,E. and Elazar,Z. (2011) Biogenesis and cargo selectivity of autophagosomes. Annu. Rev. Biochem., 80, 125-156.
    • (2011) Annu. Rev. Biochem. , vol.80 , pp. 125-156
    • Weidberg, H.1    Shvets, E.2    Elazar, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.