-
1
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz JD, White E. Autophagy and metabolism. Science. 2010; 330: 1344-8.
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
2
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
-
Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, Sher A, Kehrl JH. Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol. 2012; 13: 255-63.
-
(2012)
Nat Immunol
, vol.13
, pp. 255-263
-
-
Shi, C.S.1
Shenderov, K.2
Huang, N.N.3
Kabat, J.4
Abu-Asab, M.5
Fitzgerald, K.A.6
Sher, A.7
Kehrl, J.H.8
-
3
-
-
64349123107
-
Autophagy mediates the mitotic senescence transition
-
Young AR, Narita M, Ferreira M, Kirschner K, Sadaie M, Darot JF, et al. Autophagy mediates the mitotic senescence transition. Genes Dev. 2009; 23: 798-803.
-
(2009)
Genes Dev
, vol.23
, pp. 798-803
-
-
Young, A.R.1
Narita, M.2
Ferreira, M.3
Kirschner, K.4
Sadaie, M.5
Darot, J.F.6
-
4
-
-
27644514227
-
Another way to die: Autophagic programmed cell death
-
Tsujimoto Y, Shimizu S. Another way to die: autophagic programmed cell death. Cell Death Differ. 2005; 12: 1528-34.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1528-1534
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
5
-
-
79952844773
-
The Unfolded Protein Response, Degradation from the Endoplasmic Reticulum, and Cancer
-
Yien Che Tsai, Allan M. Weissman. The Unfolded Protein Response, Degradation from the Endoplasmic Reticulum, and Cancer. Genes & Cancer. 2010; 7: 764-778.
-
(2010)
Genes & Cancer
, vol.7
, pp. 764-778
-
-
Tsai Yien, C.1
Weissman, A.M.2
-
6
-
-
84863631235
-
Targeting endoplasmic reticulum stress for cancer therapy
-
Schonthal AH. Targeting endoplasmic reticulum stress for cancer therapy. Front Biosci (Schol Ed). 2012; 4: 412-31.
-
(2012)
Front Biosci (Schol Ed)
, vol.4
, pp. 412-431
-
-
Schonthal, A.H.1
-
7
-
-
15944375438
-
Endoplasmic reticulum stress-induced apoptosis is partly mediated by reduced insulin signaling throughphosphatidylinositol 3-kinase/Akt and increased glycogen synthase kinase-3beta in mouse insulinoma cells
-
Srinivasan S, Ohsugi M, Liu Z, Fatrai S, Bernal-Mizrachi E, Permutt MA. Endoplasmic reticulum stress-induced apoptosis is partly mediated by reduced insulin signaling throughphosphatidylinositol 3-kinase/Akt and increased glycogen synthase kinase-3beta in mouse insulinoma cells. Diabetes. 2005; 54: 968-75.
-
(2005)
Diabetes
, vol.54
, pp. 968-975
-
-
Srinivasan, S.1
Ohsugi, M.2
Liu, Z.3
Fatrai, S.4
Bernal-Mizrachi, E.5
Permutt, M.A.6
-
8
-
-
79952310800
-
Adaptive unfolded protein response attenuates alcohol-induced pancreatic damage
-
Lugea A, Tischler D, Nguyen J, Gong J, Gukovsky I, French SW, Gorelick FS, Pandol SJ. Adaptive unfolded protein response attenuates alcohol-induced pancreatic damage. Gastroenterology. 2011; 140: 987-97.
-
(2011)
Gastroenterology
, vol.140
, pp. 987-997
-
-
Lugea, A.1
Tischler, D.2
Nguyen, J.3
Gong, J.4
Gukovsky, I.5
French, S.W.6
Gorelick, F.S.7
Pandol, S.J.8
-
9
-
-
57049117856
-
Cell death and endoplasmic reticulum stress: Disease relevance and therapeutic opportunities
-
Kim I, Xu W, Reed JC. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov. 2008; 7: 1013-30.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 1013-1030
-
-
Kim, I.1
Xu, W.2
Reed, J.C.3
-
10
-
-
84979517834
-
Selection of autophagy or apoptosis in cells exposed to ER-stress depends on ATF4 expression pattern with or without CHOP expression
-
Matsumoto H, Miyazaki S, Matsuyama S, Takeda M, Kawano M, Nakagawa H, et al. Selection of autophagy or apoptosis in cells exposed to ER-stress depends on ATF4 expression pattern with or without CHOP expression. Biol Open. 2013; 2: 1084-90.
-
(2013)
Biol Open
, vol.2
, pp. 1084-1090
-
-
Matsumoto, H.1
Miyazaki, S.2
Matsuyama, S.3
Takeda, M.4
Kawano, M.5
Nakagawa, H.6
-
11
-
-
33750440743
-
ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1
-
Hiroshi S, Hideaki O, Akihiko Y, Hiroki Y. ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1. J Cell Sci. 2006; 119: 3958-3966.
-
(2006)
J Cell Sci
, vol.119
, pp. 3958-3966
-
-
Hiroshi, S.1
Hideaki, O.2
Akihiko, Y.3
Hiroki, Y.4
-
12
-
-
84878638092
-
Anticancer Effects of Bufalin on Human Hepatocellular Carcinoma HepG2 Cells: Roles of Apoptosis andAutophagy
-
Miao Q, Bi LL, Li X, Miao S, Zhang J, Zhang S, et al. Anticancer Effects of Bufalin on Human Hepatocellular Carcinoma HepG2 Cells: Roles of Apoptosis andAutophagy. Int J Mol Sci. 2013; 14: 1370-82.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 1370-1382
-
-
Miao, Q.1
Bi, L.L.2
Li, X.3
Miao, S.4
Zhang, J.5
Zhang, S.6
-
13
-
-
80052267544
-
Bufalin induces autophagy- mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation
-
Xie CM, Chan WY, Yu S, Zhao J, Cheng CH. Bufalin induces autophagy- mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation. Free Radic Biol Med. 2011; 51: 1365-75.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 1365-1375
-
-
Xie, C.M.1
Chan, W.Y.2
Yu, S.3
Zhao, J.4
Cheng, C.H.5
-
14
-
-
84863578695
-
Visualization and measurement of ATP levels in living cells replicating hepatitis C virus genome RNA
-
Ando T, Imamura H, Suzuki R, Aizaki H, Watanabe T, Wakita T, Suzuki T. Visualization and measurement of ATP levels in living cells replicating hepatitis C virus genome RNA. PLoS Pathog. 2012; 8: e1002561.
-
(2012)
PLoS Pathog
, vol.8
-
-
Ando, T.1
Imamura, H.2
Suzuki, R.3
Aizaki, H.4
Watanabe, T.5
Wakita, T.6
Suzuki, T.7
-
15
-
-
79958723738
-
Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of spinocerebellar ataxia type 12 (SCA12)
-
Wang YC, Lee CM, Lee LC, Tung LC, Hsieh-Li HM, Lee-Chen GJ, et al. Mitochondrial dysfunction and oxidative stress contribute to the pathogenesis of spinocerebellar ataxia type 12 (SCA12). J Biol Chem. 2011; 286: 21742-54.
-
(2011)
J Biol Chem
, vol.286
, pp. 21742-21754
-
-
Wang, Y.C.1
Lee, C.M.2
Lee, L.C.3
Tung, L.C.4
Hsieh-Li, H.M.5
Lee-Chen, G.J.6
-
16
-
-
84863811994
-
Oridonin up-regulates expression of P21 and induces autophagy and apoptosis in human prostate cancer cells
-
Li X, Li X, Wang J, Ye Z, Li JC. Oridonin up-regulates expression of P21 and induces autophagy and apoptosis in human prostate cancer cells. Int J Biol Sci. 2012; 8: 901-12.
-
(2012)
Int J Biol Sci
, vol.8
, pp. 901-912
-
-
Li, X.1
Li, X.2
Wang, J.3
Ye, Z.4
Li, J.C.5
-
17
-
-
80755175797
-
Hepatitis B virus X protein reduces starvation-induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway
-
Mao Y, Da L, Tang H, Yang J, Lei Y, Tiollais P, et al. Hepatitis B virus X protein reduces starvation-induced cell death through activation of autophagy and inhibition of mitochondrial apoptotic pathway. Biochem Biophys Res Commun. 2011; 415: 68-74.
-
(2011)
Biochem Biophys Res Commun
, vol.415
, pp. 68-74
-
-
Mao, Y.1
Da, L.2
Tang, H.3
Yang, J.4
Lei, Y.5
Tiollais, P.6
-
18
-
-
76449083770
-
The molecular mechanism of mitochondria autophagy in yeast
-
Kanki T, Klionsky DJ. The molecular mechanism of mitochondria autophagy in yeast. Mol Microbiol. 2010; 75: 795-800.
-
(2010)
Mol Microbiol
, vol.75
, pp. 795-800
-
-
Kanki, T.1
Klionsky, D.J.2
-
19
-
-
0036289016
-
AMP-activated protein kinase kinase: Detection with recombinant AMPK alpha1 subunit
-
Hamilton SR, O'Donnell JB Jr, Hammet A, Stapleton D, Habinowski SA, Means AR, et al. AMP-activated protein kinase kinase: detection with recombinant AMPK alpha1 subunit. Biochem Biophys Res Commun. 2002; 293: 892-8.
-
(2002)
Biochem Biophys Res Commun
, vol.293
, pp. 892-898
-
-
Hamilton, S.R.1
O'Donnell Jr., J.B.2
Hammet, A.3
Stapleton, D.4
Habinowski, S.A.5
Means, A.R.6
-
20
-
-
84862908818
-
AMPK and mTOR in cellular energy homeostasis and drug targets
-
Inoki K, Kim J, Guan KL. AMPK and mTOR in cellular energy homeostasis and drug targets. Annu Rev Pharmacol Toxicol. 2012; 52: 381-400.
-
(2012)
Annu Rev Pharmacol Toxicol
, vol.52
, pp. 381-400
-
-
Inoki, K.1
Kim, J.2
Guan, K.L.3
-
21
-
-
84874112079
-
The critical roles of endoplasmic reticulum chaperones and unfolded Protein response in tumorigenesis andanticancer therapies
-
Luo B, Lee AS. The critical roles of endoplasmic reticulum chaperones and unfolded Protein response in tumorigenesis andanticancer therapies. Oncogene. 2013; 32: 805-18.
-
(2013)
Oncogene
, vol.32
, pp. 805-818
-
-
Luo, B.1
Lee, A.S.2
-
22
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell. 2010; 140: 900-17.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
23
-
-
68949202516
-
Role of the unfolded protein response regulator BiP in development, cancer, and neurological disorders
-
Wang M, Wey S, Zhang Y, Ye R, Lee AS. Role of the unfolded protein response regulator BiP in development, cancer, and neurological disorders. Antioxid Redox Signal. 2009; 11: 2307-16.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2307-2316
-
-
Wang, M.1
Wey, S.2
Zhang, Y.3
Ye, R.4
Lee, A.S.5
-
24
-
-
79954417021
-
HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs
-
Muller C, Salvayre R, Nègre-Salvayre A, Vindis C. HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs. Cell Death Differ. 2011; 18: 817-28.
-
(2011)
Cell Death Differ
, vol.18
, pp. 817-828
-
-
Muller, C.1
Salvayre, R.2
Nègre-Salvayre, A.3
Vindis, C.4
-
25
-
-
0037039442
-
Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway
-
Tallóczy Z, Jiang W, Virgin HW 4th, Leib DA, Scheuner D, Kaufman RJ, et al. Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Proc Natl Acad Sci USA. 2002; 99: 190-5.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 190-195
-
-
Tallóczy, Z.1
Jiang, W.2
Virgin, H.W.3
Leib, D.A.4
Scheuner, D.5
Kaufman, R.J.6
-
26
-
-
70350525582
-
STAT3 Regulation of Glioblastoma Pathogenesis
-
i
-
Núria de la Iglesia, Sidharth V. Puram, Azad Bonni. STAT3 Regulation of Glioblastoma Pathogenesis. Curr Mol Med. 2009; 9: 580-590.
-
(2009)
Curr Mol Med
, vol.9
, pp. 580-590
-
-
de Iglesia Núria, L.1
Puram, S.V.2
Bonn, A.3
-
27
-
-
35349030825
-
Rhein induces apoptosis through induction of endoplasmic reticulum stress and Ca2+-dependent mitochondrial death pathway in human nasopharyngeal carcinoma cells
-
Lin ML, Chen SS, Lu YC, Liang RY, Ho YT, Yang CY, Chung JG. Rhein induces apoptosis through induction of endoplasmic reticulum stress and Ca2+-dependent mitochondrial death pathway in human nasopharyngeal carcinoma cells. Anticancer Res. 2007; 27: 3313-22.
-
(2007)
Anticancer Res
, vol.27
, pp. 3313-3322
-
-
Lin, M.L.1
Chen, S.S.2
Lu, Y.C.3
Liang, R.Y.4
Ho, Y.T.5
Yang, C.Y.6
Chung, J.G.7
-
28
-
-
79951857650
-
Unfolded protein response in cancer: The physician's perspective
-
Li X, Zhang K, Li Z. Unfolded protein response in cancer: the physician's perspective. J Hematol Oncol. 2011; 4: 8.
-
(2011)
J Hematol Oncol
, vol.4
, pp. 8
-
-
Li, X.1
Zhang, K.2
Li, Z.3
-
29
-
-
84863425318
-
Apoptosis, autophagy and ER stress in mevalonate cascade inhibition- induced cell death of human atrialfibroblasts
-
Ghavami S, Yeganeh B, Stelmack GL, Kashani HH, Sharma P, Cunnington R, et al. Apoptosis, autophagy and ER stress in mevalonate cascade inhibition- induced cell death of human atrialfibroblasts. Cell Death Dis. 2012; 3: e330.
-
(2012)
Cell Death Dis
, vol.e330
, pp. 3
-
-
Ghavami, S.1
Yeganeh, B.2
Stelmack, G.L.3
Kashani, H.H.4
Sharma, P.5
Cunnington, R.6
-
30
-
-
0032940099
-
CHOP-Dependent Stress-Inducible Expression of a Novel Form of Carbonic Anhydrase VI
-
Sok J, Wang X, Batchvarova N, Kuroda M, Harding H, Ron D. CHOP-Dependent Stress-Inducible Expression of a Novel Form of Carbonic Anhydrase VI. Mol Cell Biol. 1999; 19: 495-504.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 495-504
-
-
Sok, J.1
Wang, X.2
Batchvarova, N.3
Kuroda, M.4
Harding, H.5
Ron, D.6
-
31
-
-
77951252041
-
Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response
-
Ma Y, Shimizu Y, Mann M, Jin Y, Hendershot L. Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response. Cell Stress Chaperones. 2010; 15: 281-293.
-
(2010)
Cell Stress Chaperones
, vol.15
, pp. 281-293
-
-
Ma, Y.1
Shimizu, Y.2
Mann, M.3
Jin, Y.4
Hendershot, L.5
-
32
-
-
84863425318
-
Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts
-
Ghavami S, Yeganeh B, Stelmack G, Kashani H, Sharma P, Cunnington R, et al. Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts. Cell Death Dis. 2012; 3: e330.
-
(2012)
Cell Death Dis
, vol.e330
, pp. 3
-
-
Ghavami, S.1
Yeganeh, B.2
Stelmack, G.3
Kashani, H.4
Sharma, P.5
Cunnington, R.6
-
33
-
-
79952348567
-
Caspase-4 directly activates caspase-9 in endoplasmic reticulum stress-induced apoptosis in SH-SY5Y cells
-
Yamamuro A, Kishino T, Ohshima Y, Yoshioka Y, Kimura T, Kasai A, et al. Caspase-4 directly activates caspase-9 in endoplasmic reticulum stress-induced apoptosis in SH-SY5Y cells. J Pharmacol Sci. 2011; 115: 239-243.
-
(2011)
J Pharmacol Sci
, vol.115
, pp. 239-243
-
-
Yamamuro, A.1
Kishino, T.2
Ohshima, Y.3
Yoshioka, Y.4
Kimura, T.5
Kasai, A.6
-
34
-
-
84883658015
-
Dengue 2 infection of HepG2 liver cells results in endoplasmic reticulum stress and induction of multiple pathways of cell death
-
Thepparit C, Khakpoor A, Khongwichit S, Wikan N, Fongsaran C, Chingsuwanrote P, et al. Dengue 2 infection of HepG2 liver cells results in endoplasmic reticulum stress and induction of multiple pathways of cell death. BMC Res Notes. 2013; 6: 372.
-
(2013)
BMC Res Notes
, vol.6
, pp. 372
-
-
Thepparit, C.1
Khakpoor, A.2
Khongwichit, S.3
Wikan, N.4
Fongsaran, C.5
Chingsuwanrote, P.6
-
36
-
-
63849308518
-
Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells
-
Oh SH, Lim SC. Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells. J Pharmacol Exp Ther. 2009; 329: 112-22.
-
(2009)
J Pharmacol Exp Ther
, vol.329
, pp. 112-122
-
-
Oh, S.H.1
Lim, S.C.2
-
37
-
-
65949095803
-
Autophagy regulates lipid metabolism
-
Singh R, Kaushik S, Wang Y, Xiang YQ, Novak I, Komatsu M, et al. Autophagy regulates lipid metabolism. Nature. 2009; 458: 1131-1135.
-
(2009)
Nature
, vol.458
, pp. 1131-1135
-
-
Singh, R.1
Kaushik, S.2
Wang, Y.3
Xiang, Y.Q.4
Novak, I.5
Komatsu, M.6
-
38
-
-
78650835111
-
Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway
-
Vucicevic L, Misirkic M, Janjetovic K, Vilimanovich U, Sudar E, Isenovic E, et al. Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway. Autophagy. 2011; 7: 40-50.
-
(2011)
Autophagy
, vol.7
, pp. 40-50
-
-
Vucicevic, L.1
Misirkic, M.2
Janjetovic, K.3
Vilimanovich, U.4
Sudar, E.5
Isenovic, E.6
-
39
-
-
79951827477
-
AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor
-
Liu JL, Mao Z, Gallick GE, Yung WK. AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor. Neuro Oncol. 2011; 13: 184-94.
-
(2011)
Neuro Oncol
, vol.13
, pp. 184-194
-
-
Liu, J.L.1
Mao, Z.2
Gallick, G.E.3
Yung, W.K.4
-
40
-
-
84860877843
-
Maurizi MR. 4-O-carboxymethyl ascochlorin causes ER stress and induced autophagy in human hepatocellular carcinoma cells
-
Kang JH, Chang YC, Maurizi MR. 4-O-carboxymethyl ascochlorin causes ER stress and induced autophagy in human hepatocellular carcinoma cells. J Biol Chem. 2012; 287: 15661-71.
-
(2012)
J Biol Chem
, vol.287
, pp. 15661-15671
-
-
Kang, J.H.1
Chang, Y.C.2
-
41
-
-
84857217832
-
ER stress and its functional link to mitochondria: Role in cell survival and death
-
Malhotra JD, Kaufman RJ. ER stress and its functional link to mitochondria: role in cell survival and death. Cold Spring Harb Perspect Biol. 2011; 3: a004424.
-
(2011)
Cold Spring Harb Perspect Biol
, vol.a004424
, pp. 3
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
42
-
-
77955006485
-
Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells
-
Meister S, Frey B, Lang VR, Gaipl US, Schett G, Schlötzer-Schrehardt U, et al. Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells. Neoplasia. 2010 Jul;12(7):550-61.
-
(2010)
Neoplasia
, vol.12
, Issue.7
, pp. 550-561
-
-
Meister, S.1
Frey, B.2
Lang, V.R.3
Gaipl, U.S.4
Schett, G.5
Schlötzer-Schrehardt, U.6
|