SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition

Journal of Biological Chemistry

Volumn 284, Issue 17, 2009, Pages 11318-11325

  Noh, Jee Yeon ^a,b   Lee, Huikyong ^b   Song, Sungmin ^b   Kim, Nam Soon ^c   Im, Wooseok ^d   Kim, Manho ^d   Seo, Hyemyung ^e   Chung, Chul Woong ^a   Chang, Jae Woong ^b   Ferrante, Robert J ^f   Yoo, Young Jun ^a   Ryu, Hoon ^f   Jung, Yong Keun ^b  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Seoul National University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^d Seoul National University Hospital   (South Korea)

^e Hanyang University   (South Korea)

^f BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL-BASED; DOWN-REGULATION; ECTOPIC EXPRESSIONS; ENDOCYTOSIS PATHWAY; ENDOPLASMIC RETICULUM STRESS; ER STRESS; HUNTINGTON DISEASE; INTRAPERITONEAL INJECTIONS; MUTANT HUNTINGTIN; POLYGLUTAMINE; POLYGLUTAMINE PROTEINS; STRIATAL NEURONS; STRIATUM; TUNICAMYCIN; UBIQUITIN;

PROTEINS;

COMPLEMENTARY DNA; HUNTINGTIN; MEMBRANE PROTEIN; MUTANT PROTEIN; POLYGLUTAMINE; SECRETORY CARRIER MEMBRANE PROTEIN 5; TUNICAMYCIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; HDH PROTEIN, RAT; NERVE PROTEIN; NUCLEAR PROTEIN; PEPTIDE; SCAMP5 PROTEIN, HUMAN; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, HUMAN; SLC6A4 PROTEIN, MOUSE;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; ENDOCYTOSIS; ENDOPLASMIC RETICULUM STRESS; EXPERIMENTAL MOUSE; HUMAN; HUMAN CELL; HUMAN TISSUE; HUNTINGTON CHOREA; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; UPREGULATION; ANIMAL; BRAIN; ENDOPLASMIC RETICULUM; GENETICS; METABOLISM; MUTATION; PRENATAL DEVELOPMENT; TRANSGENIC MOUSE;

MUS;

ANIMALS; BRAIN; CARRIER PROTEINS; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; HUMANS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; RATS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; UP-REGULATION;

EID: 66449112462     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807620200     Document Type: Article

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