Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy

Nature Cell Biology

Volumn 14, Issue 8, 2012, Pages 829-837

  Van Der Vos, Kristan E ^a,e   Eliasson, Pernilla ^a   Proikas Cezanne, Tassula ^b   Vervoort, Stephin J ^a,d   Van Boxtel, Ruben ^a   Putker, Marrit ^a   Van Zutphen, Iris J ^a   Mauthe, Mario ^b   Zellmer, Sebastian ^c   Pals, Cornelieke ^a   Verhagen, Liesbeth P ^a   Koerkamp, Marian J A Groot ^a   Koen Braat, A ^a,d   Dansen, Tobias B ^a   Holstege, Frank C ^a   Gebhardt, Rolf ^c   Burgering, Boudewijn M ^a   Coffer, Paul J ^a,d  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE AMMONIA LIGASE; GLUTAMINE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN KINASE B; PROTEIN P62; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR FOXO4; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; AMINO ACID SYNTHESIS; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL LEVEL; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; METABOLIC REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALS; AUTOPHAGY; BASE SEQUENCE; BLOTTING, WESTERN; CELL PROLIFERATION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GLUTAMATE SYNTHASE; GLUTAMINE; HUMANS; MICE; MICROARRAY ANALYSIS; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOL 3-KINASES; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES; RATS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

EID: 84864878724     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2536     Document Type: Article

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