Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: Involvement of the proteasome and ER stress-activated kinase IRE1α

Human Molecular Genetics

Volumn 23, Issue 22, 2014, Pages 5928-5939

  Hyrskyluoto, Alise ^a,b   Bruelle, Céline ^a,b   Lundh, Sofia H ^c   Do, Hai Thi ^a,b   Kivinen, Jenny ^a,b   Rappou, Elisabeth ^a,b   Reijonen, Sami ^b   Waltimo, Tuure ^b   Petersén, Åsa ^c   Lindholm, Dan ^a,b   Korhonen, Laura ^a,b,d  

^a UNIVERSITY OF HELSINKI   (Finland)

^b MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^c LUND UNIVERSITY   (Sweden)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; DEUBIQUITINASE; HUNTINGTIN; INOSITOL REQUIRING ENZYME 1 ALPHA; MEMBRANE PROTEIN; PROTEASOME; UBIQUITIN SPECIFIC PROTEASE 14; UNCLASSIFIED DRUG; ERN1 PROTEIN, MOUSE; PROTEIN AGGREGATE; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, MOUSE; UBIQUITIN; UBIQUITIN THIOLESTERASE; USP14 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL AGGREGATION; CELL DEGENERATION; CELL FUNCTION; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM MEMBRANE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GENE OVEREXPRESSION; HELA CELL LINE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN METABOLISM; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENETICS; HUNTINGTON CHOREA; METABOLISM; PATHOPHYSIOLOGY;

ANIMALS; CELL AGGREGATION; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FEMALE; HUMANS; HUNTINGTON DISEASE; MICE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN AGGREGATES; PROTEIN-SERINE-THREONINE KINASES; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; UBIQUITIN; UBIQUITIN THIOLESTERASE;

EID: 84911440935     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu317     Document Type: Article

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