-
1
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz JD, White E. Autophagy and metabolism. Science 2010; 330:1344-1348.
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
2
-
-
4544385218
-
Autophagy: Many paths to the same end
-
DOI 10.1023/B:MCBI.0000041848.57020.57
-
Cuervo AM. Autophagy: many paths to the same end. Mol Cell Biochem 2004; 263:55-72. (Pubitemid 39256145)
-
(2004)
Molecular and Cellular Biochemistry
, vol.263
, Issue.1
, pp. 55-72
-
-
Cuervo, A.M.1
-
4
-
-
77957654940
-
Autophagic degradation of active caspase-8: A crosstalk mechanism between autophagy and apoptosis
-
Hou W, Han J, Lu C, Goldstein LA, Rabinowich H. Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis. Autophagy 2010; 6:891-900.
-
(2010)
Autophagy
, vol.6
, pp. 891-900
-
-
Hou, W.1
Han, J.2
Lu, C.3
Goldstein, L.A.4
Rabinowich, H.5
-
5
-
-
77955172368
-
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
-
Gao C, Cao W, Bao L, et al. Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation. Nat Cell Biol 2010; 12:781-790.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 781-790
-
-
Gao, C.1
Cao, W.2
Bao, L.3
-
7
-
-
78649348967
-
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
-
Sengupta S, Peterson TR, Sabatini DM. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol Cell 2010; 40:310-322.
-
(2010)
Mol Cell
, vol.40
, pp. 310-322
-
-
Sengupta, S.1
Peterson, T.R.2
Sabatini, D.M.3
-
8
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
-
Hosokawa N, Hara T, Kaizuka T, et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell 2009; 20:1981-1991.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
-
9
-
-
66449083078
-
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
-
Ganley IG, Lam du H, Wang J, Ding X, Chen S, Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J Biol Chem 2009; 284:12297-12305.
-
(2009)
J Biol Chem
, vol.284
, pp. 12297-12305
-
-
Ganley, I.G.1
Lam Du, H.2
Wang, J.3
Ding, X.4
Chen, S.5
Jiang, X.6
-
10
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
Jung CH, Jun CB, Ro SH, et al. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell 2009; 20:1992-2003.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
-
11
-
-
67549110195
-
A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy
-
Mercer CA, Kaliappan A, Dennis PB. A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy. Autophagy 2009; 5:649-662.
-
(2009)
Autophagy
, vol.5
, pp. 649-662
-
-
Mercer, C.A.1
Kaliappan, A.2
Dennis, P.B.3
-
12
-
-
70349644856
-
Atg101, a novel mammalian autophagy protein interacting with Atg13
-
Hosokawa N, Sasaki T, Iemura S, Natsume T, Hara T, Mizushima N. Atg101, a novel mammalian autophagy protein interacting with Atg13. Autophagy 2009; 5:973-979.
-
(2009)
Autophagy
, vol.5
, pp. 973-979
-
-
Hosokawa, N.1
Sasaki, T.2
Iemura, S.3
Natsume, T.4
Hara, T.5
Mizushima, N.6
-
13
-
-
77957728513
-
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
-
Di Bartolomeo S, Corazzari M, Nazio F, et al. The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy. J Cell Biol 2010; 191:155-168.
-
(2010)
J Cell Biol
, vol.191
, pp. 155-168
-
-
Di Bartolomeo, S.1
Corazzari, M.2
Nazio, F.3
-
14
-
-
33745086418
-
Assortment of phosphatidylinositol 3-kinase complexes-Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae
-
DOI 10.1091/mbc.E05-09-0841
-
Obara K, Sekito T, Ohsumi Y. Assortment of phosphati-dylinositol 3-kinase complexes - Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. Mol Biol Cell 2006; 17:1527-1539. (Pubitemid 44011573)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.4
, pp. 1527-1539
-
-
Obara, K.1
Sekito, T.2
Ohsumi, Y.3
-
15
-
-
77950491704
-
New insights into the function of Atg9
-
Webber JL, Tooze SA. New insights into the function of Atg9. FEBS Lett 2010; 584:1319-1326.
-
(2010)
FEBS Lett
, vol.584
, pp. 1319-1326
-
-
Webber, J.L.1
Tooze, S.A.2
-
16
-
-
33750366092
-
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes
-
DOI 10.1242/jcs.03172
-
Young AR, Chan EY, Hu XW, et al. Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci 2006; 119:3888-3900. (Pubitemid 44614440)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.18
, pp. 3888-3900
-
-
Young, A.R.J.1
Chan, E.Y.W.2
Hu, X.W.3
Kochl, R.4
Crawshaw, S.G.5
High, S.6
Halley, D.W.7
Lippincott-Schwartz, J.8
Tooze, S.A.9
-
17
-
-
79951805767
-
Atg1-mediated myosin II activation regulates autophago-some formation during starvation-induced autophagy
-
Tang HW, Wang YB, Wang SL, Wu MH, Lin SY, Chen GC. Atg1-mediated myosin II activation regulates autophago-some formation during starvation-induced autophagy. EMBO J 2011; 30:636-651.
-
(2011)
EMBO J
, vol.30
, pp. 636-651
-
-
Tang, H.W.1
Wang, Y.B.2
Wang, S.L.3
Wu, M.H.4
Lin, S.Y.5
Chen, G.C.6
-
18
-
-
79956095420
-
Autophagosome formation and molecular mechanism of autophagy
-
Tanida I. Autophagosome formation and molecular mechanism of autophagy. Antioxid Redox Signal 2011; 14:2201-2214.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 2201-2214
-
-
Tanida, I.1
-
19
-
-
77951237303
-
The Beclin 1 interactome
-
He C, Levine B. The Beclin 1 interactome. Curr Opin Cell Biol 2010; 22:140-149.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 140-149
-
-
He, C.1
Levine, B.2
-
20
-
-
77953543377
-
The Beclin 1-VPS34 complex - At the crossroads of autophagy and beyond
-
Funderburk SF, Wang QJ, Yue Z. The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond. Trends Cell Biol 2010; 20:355-362.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 355-362
-
-
Funderburk, S.F.1
Wang, Q.J.2
Yue, Z.3
-
21
-
-
77953726483
-
Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
-
Polson HE, de Lartigue J, Rigden DJ, et al. Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation. Autophagy 2010; 6:506-522.
-
(2010)
Autophagy
, vol.6
, pp. 506-522
-
-
Polson, H.E.1
De Lartigue, J.2
Rigden, D.J.3
-
22
-
-
0038325675
-
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
-
DOI 10.1242/jcs.00381
-
Mizushima N, Kuma A, Kobayashi Y, et al. Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci 2003; 116:1679-1688. (Pubitemid 36582155)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.9
, pp. 1679-1688
-
-
Mizushima, N.1
Kuma, A.2
Kobayashi, Y.3
Yamamoto, A.4
Matsubae, M.5
Takao, T.6
Natsume, T.7
Ohsumi, Y.8
Yoshimori, T.9
-
23
-
-
0037166241
-
Formation of the 350-kDa Apg12-Apg Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast
-
DOI 10.1074/jbc.M111889200
-
Kuma A, Mizushima N, Ishihara N, Ohsumi Y. Formation of the approximately 350-kDa Apg12-Apg5. Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 2002; 277:18619-18625. (Pubitemid 34952416)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.21
, pp. 18619-18625
-
-
Kuma, A.1
Mizushima, N.2
Ishihara, N.3
Ohsumi, Y.4
-
24
-
-
43949143804
-
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
-
Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 2008; 19:2092-2100.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2092-2100
-
-
Fujita, N.1
Itoh, T.2
Omori, H.3
Fukuda, M.4
Noda, T.5
Yoshimori, T.6
-
25
-
-
4344604111
-
A receptor-associated protein-phospholipid conjugates
-
DOI 10.1074/jbc.M401461200
-
Tanida I, Sou YS, Ezaki J, Minematsu-Ikeguchi N, Ueno T, Kominami E. HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. J Biol Chem 2004; 279:36268-36276. (Pubitemid 39128963)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.35
, pp. 36268-36276
-
-
Tanida, I.1
Sou, Y.-S.2
Ezaki, J.3
Minematsu-Ikeguchi, N.4
Ueno, T.5
Kominami, E.6
-
26
-
-
3242888703
-
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
-
DOI 10.1242/jcs.01131
-
Kabeya Y, Mizushima N, Yamamoto A, Oshitani-Okamoto S, Ohsumi Y, Yoshimori T. LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci 2004; 117:2805-2812. (Pubitemid 38997262)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2805-2812
-
-
Kabeya, Y.1
Mizushima, N.2
Yamamoto, A.3
Oshitani-Okamoto, S.4
Ohsumi, Y.5
Yoshimori, T.6
-
27
-
-
33645120442
-
Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes
-
Kochl R, Hu XW, Chan EY, Tooze SA. Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes. Traffic 2006; 7:129-145.
-
(2006)
Traffic
, vol.7
, pp. 129-145
-
-
Kochl, R.1
Hu, X.W.2
Chan, E.Y.3
Tooze, S.A.4
-
28
-
-
79953153833
-
The late stage of autophagy: Cellular events and molecular regulation
-
Tong J, Yan X, Yu L. The late stage of autophagy: cellular events and molecular regulation. Protein Cell 2010; 1:907-915.
-
(2010)
Protein Cell
, vol.1
, pp. 907-915
-
-
Tong, J.1
Yan, X.2
Yu, L.3
-
29
-
-
40449139980
-
The itinerary of autophagosomes: From peripheral formation to kiss-and-run fusion with lysosomes
-
DOI 10.1111/j.1600-0854.2008.00701.x
-
Jahreiss L, Menzies FM, Rubinsztein DC. The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes. Traffic 2008; 9:574-587. (Pubitemid 351351616)
-
(2008)
Traffic
, vol.9
, Issue.4
, pp. 574-587
-
-
Jahreiss, L.1
Menzies, F.M.2
Rubinsztein, D.C.3
-
30
-
-
33845407202
-
Atg22 recycles amino acids to link the degradative and recycling functions of autophagy
-
DOI 10.1091/mbc.E06-06-0479
-
Yang Z, Huang J, Geng J, Nair U, Klionsky DJ. Atg22 recycles amino acids to link the degradative and recycling functions of autophagy. Mol Biol Cell 2006; 17:5094-5104. (Pubitemid 44907353)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.12
, pp. 5094-5104
-
-
Yang, Z.1
Huang, J.2
Geng, J.3
Nair, U.4
Klionsky, D.J.5
-
31
-
-
50249084987
-
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
-
Axe EL, Walker SA, Manifava M, et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 2008; 182:685-701.
-
(2008)
J Cell Biol
, vol.182
, pp. 685-701
-
-
Axe, E.L.1
Walker, S.A.2
Manifava, M.3
-
32
-
-
77952495224
-
Mitochondria supply membranes for autophagosome biogenesis during starvation
-
Hailey DW, Rambold AS, Satpute-Krishnan P, et al. Mitochondria supply membranes for autophagosome biogenesis during starvation. Cell 2010; 141:656-667.
-
(2010)
Cell
, vol.141
, pp. 656-667
-
-
Hailey, D.W.1
Rambold, A.S.2
Satpute-Krishnan, P.3
-
33
-
-
77955131007
-
Plasma membrane contributes to the formation of preautophagosomal structures
-
Ravikumar B, Moreau K, Jahreiss L, Puri C, Rubinsztein DC. Plasma membrane contributes to the formation of preautophagosomal structures. Nat cell biol 2010; 12:747-757.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 747-757
-
-
Ravikumar, B.1
Moreau, K.2
Jahreiss, L.3
Puri, C.4
Rubinsztein, D.C.5
-
34
-
-
70349641036
-
Nuclear membranederived autophagy, a novel process that participates in the presentation of endogenous viral antigens during HSV-1 infection
-
English L, Chemali M, Desjardins M. Nuclear membranederived autophagy, a novel process that participates in the presentation of endogenous viral antigens during HSV-1 infection. Autophagy 2009; 5:1026-1029.
-
(2009)
Autophagy
, vol.5
, pp. 1026-1029
-
-
English, L.1
Chemali, M.2
Desjardins, M.3
-
35
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu M, Waguri S, Chiba T, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441:880-884.
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
-
36
-
-
34249714158
-
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
-
DOI 10.1038/nm1574, PII NM1574
-
Nakai A, Yamaguchi O, Takeda T, et al. The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress. Nat Med 2007; 13:619-624. (Pubitemid 46828485)
-
(2007)
Nature Medicine
, vol.13
, Issue.5
, pp. 619-624
-
-
Nakai, A.1
Yamaguchi, O.2
Takeda, T.3
Higuchi, Y.4
Hikoso, S.5
Taniike, M.6
Omiya, S.7
Mizote, I.8
Matsumura, Y.9
Asahi, M.10
Nishida, K.11
Hori, M.12
Mizushima, N.13
Otsu, K.14
-
37
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T, Nakamura K, Matsui M, et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441:885-889.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
-
38
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
DOI 10.1083/jcb.200412022
-
Komatsu M, Waguri S, Ueno T, et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 2005; 169:425-434. (Pubitemid 40686693)
-
(2005)
Journal of Cell Biology
, vol.169
, Issue.3
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
Ezaki, J.7
Mizushima, N.8
Ohsumi, Y.9
Uchiyama, Y.10
Kominami, E.11
Tanaka, K.12
Chiba, T.13
-
39
-
-
0036345454
-
CHIP is associated with Parkin, a gene responsible for familial Parkinson's Disease, and enhances its ubiquitin ligase activity
-
DOI 10.1016/S1097-2765(02)00583-X
-
Imai Y, Soda M, Hatakeyama S, et al. CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol Cell 2002; 10:55-67. (Pubitemid 34876562)
-
(2002)
Molecular Cell
, vol.10
, Issue.1
, pp. 55-67
-
-
Imai, Y.1
Soda, M.2
Hatakeyama, S.3
Akagi, T.4
Hashikawa, T.5
Nakayama, K.-I.6
Takahashi, R.7
-
40
-
-
0346727127
-
Protein degradation and protection against misfolded or damaged proteins
-
DOI 10.1038/nature02263
-
Goldberg AL. Protein degradation and protection against misfolded or damaged proteins. Nature 2003; 426:895-899. (Pubitemid 38056882)
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 895-899
-
-
Goldberg, A.L.1
-
41
-
-
60849099049
-
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates
-
Kirkin V, Lamark T, Sou YS, et al. A role for NBR1 in autophagosomal degradation of ubiquitinated substrates. Mol Cell 2009; 33:505-516.
-
(2009)
Mol Cell
, vol.33
, pp. 505-516
-
-
Kirkin, V.1
Lamark, T.2
Sou, Y.S.3
-
42
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy*[S]
-
DOI 10.1074/jbc.M702824200
-
Pankiv S, Clausen TH, Lamark T, et al. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282:24131-24145. (Pubitemid 47328003)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.33
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.-A.5
Outzen, H.6
Overvatn, A.7
Bjorkoy, G.8
Johansen, T.9
-
43
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
-
DOI 10.1016/j.cell.2007.10.035, PII S0092867407013542
-
Komatsu M, Waguri S, Koike M, et al. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 2007; 131:1149-1163. (Pubitemid 350235021)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
Sou, Y.-s.4
Ueno, T.5
Hara, T.6
Mizushima, N.7
Iwata, J.-i.8
Ezaki, J.9
Murata, S.10
Hamazaki, J.11
Nishito, Y.12
Iemura, S.-i.13
Natsume, T.14
Yanagawa, T.15
Uwayama, J.16
Warabi, E.17
Yoshida, H.18
Ishii, T.19
Kobayashi, A.20
Yamamoto, M.21
Yue, Z.22
Uchiyama, Y.23
Kominami, E.24
Tanaka, K.25
more..
-
44
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
DOI 10.1038/nature05853, PII NATURE05853
-
Pandey UB, Nie Z, Batlevi Y, et al. HDAC6 rescues neurode-generation and provides an essential link between autophagy and the UPS. Nature 2007; 447:859-863. (Pubitemid 46920134)
-
(2007)
Nature
, vol.447
, Issue.7146
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
Nedelsky, N.B.6
Schwartz, S.L.7
Diprospero, N.A.8
Knight, M.A.9
Schuldiner, O.10
Padmanabhan, R.11
Hild, M.12
Berry, D.L.13
Garza, D.14
Hubbert, C.C.15
Yao, T.-P.16
Baehrecke, E.H.17
Taylor, J.P.18
-
45
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
DOI 10.1016/S0092-8674(03)00939-5
-
Kawaguchi Y, Kovacs JJ, McLaurin A, Vance JM, Ito A, Yao TP. The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell 2003; 115:727-738. (Pubitemid 38030301)
-
(2003)
Cell
, vol.115
, Issue.6
, pp. 727-738
-
-
Kawaguchi, Y.1
Kovacs, J.J.2
McLaurin, A.3
Vance, J.M.4
Ito, A.5
Yao, T.-P.6
-
46
-
-
79952319773
-
Mitochondria removal by autophagy
-
Wang K, Klionsky DJ. Mitochondria removal by autophagy. Autophagy 2011; 7:297-300.
-
(2011)
Autophagy
, vol.7
, pp. 297-300
-
-
Wang, K.1
Klionsky, D.J.2
-
47
-
-
4644273585
-
Uth1p is involved in the autophagic degradation of mitochondria
-
DOI 10.1074/jbc.M406960200
-
Kissova I, Deffieu M, Manon S, Camougrand N. Uth1p is involved in the autophagic degradation of mitochondria. J Biol Chem 2004; 279:39068-39074. (Pubitemid 39296069)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.37
, pp. 39068-39074
-
-
Kissova, I.1
Deffieu, M.2
Manon, S.3
Camougrand, N.4
-
48
-
-
34247172582
-
Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival
-
DOI 10.1074/jbc.M605940200
-
Tal R, Winter G, Ecker N, Klionsky DJ, Abeliovich H. Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival. J Biol Chem 2007; 282:5617-5624. (Pubitemid 47093789)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.8
, pp. 5617-5624
-
-
Tal, R.1
Winter, G.2
Ecker, N.3
Klionsky, D.J.4
Abeliovich, H.5
-
49
-
-
37649017266
-
NIX is required for programmed mitochondrial clearance during reticulocyte maturation
-
Schweers RL, Zhang J, Randall MS, et al. NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proc Natl Acad Sci USA 2007; 104:19500-19505.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19500-19505
-
-
Schweers, R.L.1
Zhang, J.2
Randall, M.S.3
-
50
-
-
79954577302
-
Targeting mitochondrial dysfunction: Role for PINK1 and Parkin in mitochondrial quality control
-
Narendra DP, Youle RJ. Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control. Antioxid Redox Signal 2011; 14:1929-1938.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 1929-1938
-
-
Narendra, D.P.1
Youle, R.J.2
-
51
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza C, Zhou C, Huang Y, et al. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc Natl Acad Sci USA 2010; 107:378-383.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
-
52
-
-
77957686348
-
Uncovering the roles of PINK1 and parkin in mitophagy
-
Matsuda N, Tanaka K. Uncovering the roles of PINK1 and parkin in mitophagy. Autophagy 2010; 6:952-954.
-
(2010)
Autophagy
, vol.6
, pp. 952-954
-
-
Matsuda, N.1
Tanaka, K.2
-
53
-
-
56049091236
-
PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
-
Kim Y, Park J, Kim S, et al. PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem Biophys Res Commun 2008; 377:975-980.
-
(2008)
Biochem Biophys Res Commun
, vol.377
, pp. 975-980
-
-
Kim, Y.1
Park, J.2
Kim, S.3
-
54
-
-
67349239050
-
Parkin stabilizes PINK1 through direct interaction
-
Shiba K, Arai T, Sato S, et al. Parkin stabilizes PINK1 through direct interaction. Biochem Biophys Res Commun 2009; 383:331-335.
-
(2009)
Biochem Biophys Res Commun
, vol.383
, pp. 331-335
-
-
Shiba, K.1
Arai, T.2
Sato, S.3
-
55
-
-
77952242572
-
The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy
-
Michiorri S, Gelmetti V, Giarda E, et al. The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy. Cell Death Differ 2010; 17:962-974.
-
(2010)
Cell Death Differ
, vol.17
, pp. 962-974
-
-
Michiorri, S.1
Gelmetti, V.2
Giarda, E.3
-
56
-
-
77956416339
-
Autophagy in mammalian development and differentiation
-
Mizushima N, Levine B. Autophagy in mammalian development and differentiation. Nat Cell Biol 2010; 12:823-830.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 823-830
-
-
Mizushima, N.1
Levine, B.2
-
57
-
-
77950501572
-
Autophagy in the fission yeast Schizosaccharomyces pombe
-
Mukaiyama H, Nakase M, Nakamura T, Kakinuma Y, Takegawa K. Autophagy in the fission yeast Schizosaccharomyces pombe. FEBS Lett 2010; 584:1327-1334.
-
(2010)
FEBS Lett
, vol.584
, pp. 1327-1334
-
-
Mukaiyama, H.1
Nakase, M.2
Nakamura, T.3
Kakinuma, Y.4
Takegawa, K.5
-
58
-
-
0037705403
-
Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum
-
DOI 10.1074/jbc.M212467200
-
Otto GP, Wu MY, Kazgan N, Anderson OR, Kessin RH. Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum. J Biol Chem 2003; 278:17636-17645. (Pubitemid 36799365)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.20
, pp. 17636-17645
-
-
Otto, G.P.1
Wu, M.Y.2
Kazgan, N.3
Anderson, O.R.4
Kessin, R.H.5
-
59
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. elegans
-
DOI 10.1126/science.1087782
-
Melendez A, Talloczy Z, Seaman M, Eskelinen EL, Hall DH, Levine B. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 2003; 301:1387-1391. (Pubitemid 37075816)
-
(2003)
Science
, vol.301
, Issue.5638
, pp. 1387-1391
-
-
Melendez, A.1
Talloczy, Z.2
Seaman, M.3
Eskelinen, E.-L.4
Hall, D.H.5
Levine, B.6
-
60
-
-
23944448372
-
Inactivation of the autophagy Gene bec-1 triggers apoptotic cell death in C. elegans
-
DOI 10.1016/j.cub.2005.07.035, PII S0960982205007906
-
Takacs-Vellai K, Vellai T, Puoti A, et al. Inactivation of the autophagy gene bec-1 triggers apoptotic cell death in C. elegans. Curr Biol 2005; 15:1513-1517. (Pubitemid 41187492)
-
(2005)
Current Biology
, vol.15
, Issue.16
, pp. 1513-1517
-
-
Takacs-Vellai, K.1
Vellai, T.2
Puoti, A.3
Passannante, M.4
Wicky, C.5
Streit, A.6
Kovacs, A.L.7
Muller, F.8
-
61
-
-
0036387157
-
Steroid regulation of midgut cell death during Drosophila development
-
Lee CY, Cooksey BA, Baehrecke EH. Steroid regulation of midgut cell death during Drosophila development. Dev Biol 2002; 250:101-111.
-
(2002)
Dev Biol
, vol.250
, pp. 101-111
-
-
Lee, C.Y.1
Cooksey, B.A.2
Baehrecke, E.H.3
-
62
-
-
36849088609
-
Growth Arrest and Autophagy Are Required for Salivary Gland Cell Degradation in Drosophila
-
DOI 10.1016/j.cell.2007.10.048, PII S009286740701402X
-
Berry DL, Baehrecke EH. Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila. Cell 2007; 131:1137-1148. (Pubitemid 350235023)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1137-1148
-
-
Berry, D.L.1
Baehrecke, E.H.2
-
63
-
-
36849021043
-
Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila
-
DOI 10.1101/gad.1600707
-
Juhasz G, Erdi B, Sass M, Neufeld TP. Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. Genes Dev 2007; 21:3061-3066. (Pubitemid 350223523)
-
(2007)
Genes and Development
, vol.21
, Issue.23
, pp. 3061-3066
-
-
Juhasz, G.1
Erdi, B.2
Sass, M.3
Neufeld, T.P.4
-
64
-
-
70449727080
-
Autophagy promotes synapse development in Drosophila
-
Shen W, Ganetzky B. Autophagy promotes synapse development in Drosophila. J Cell Biol 2009; 187:71-79.
-
(2009)
J Cell Biol
, vol.187
, pp. 71-79
-
-
Shen, W.1
Ganetzky, B.2
-
65
-
-
46849115787
-
Autophagy is essential for preimplantation development of mouse embryos
-
DOI 10.1126/science.1154822
-
Tsukamoto S, Kuma A, Murakami M, Kishi C, Yamamoto A, Mizushima N. Autophagy is essential for preimplantation development of mouse embryos. Science 2008; 321:117-120. (Pubitemid 351956245)
-
(2008)
Science
, vol.321
, Issue.5885
, pp. 117-120
-
-
Tsukamoto, S.1
Kuma, A.2
Murakami, M.3
Kishi, C.4
Yamamoto, A.5
Mizushima, N.6
-
66
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
DOI 10.1073/pnas.2436255100
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 2003; 100:15077-15082. (Pubitemid 37518019)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.25
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
67
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
DOI 10.1172/JCI200320039
-
Qu X, Yu J, Bhagat G, et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 2003; 112:1809-1820. (Pubitemid 38063704)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
Rosen, J.7
Eskelinen, E.-L.8
Mizushima, N.9
Ohsumi, Y.10
Cattoretti, G.11
Levine, B.12
-
68
-
-
33847404337
-
Autophagy Gene-Dependent Clearance of Apoptotic Cells during Embryonic Development
-
DOI 10.1016/j.cell.2006.12.044, PII S009286740700178X
-
Qu X, Zou Z, Sun Q, et al. Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell 2007; 128:931-946. (Pubitemid 46341412)
-
(2007)
Cell
, vol.128
, Issue.5
, pp. 931-946
-
-
Qu, X.1
Zou, Z.2
Sun, Q.3
Luby-Phelps, K.4
Cheng, P.5
Hogan, R.N.6
Gilpin, C.7
Levine, B.8
-
69
-
-
43149090064
-
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
-
DOI 10.1083/jcb.200712064
-
Hara T, Takamura A, Kishi C, et al. FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol 2008; 181:497-510. (Pubitemid 351645039)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.3
, pp. 497-510
-
-
Hara, T.1
Takamura, A.2
Kishi, C.3
Iemura, S.-I.4
Natsume, T.5
Guan, J.-L.6
Mizushima, N.7
-
70
-
-
34347344990
-
Ambra1 regulates autophagy and development of the nervous system
-
DOI 10.1038/nature05925, PII NATURE05925
-
Fimia GM, Stoykova A, Romagnoli A, et al. Ambra1 regulates autophagy and development of the nervous system. Nature 2007; 447:1121-1125. (Pubitemid 47014434)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1121-1125
-
-
Maria Fimia, G.1
Stoykova, A.2
Romagnoli, A.3
Giunta, L.4
Di Bartolomeo, S.5
Nardacci, R.6
Corazzari, M.7
Fuoco, C.8
Ucar, A.9
Schwartz, P.10
Gruss, P.11
Piacentini, M.12
Chowdhury, K.13
Cecconi, F.14
-
71
-
-
34547132328
-
Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
-
DOI 10.1074/jbc.M701194200
-
Marino G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N, Lopez-Otin C. Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J Biol Chem 2007; 282:18573-18583. (Pubitemid 47100226)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.25
, pp. 18573-18583
-
-
Marino, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
Lopez-Otin, C.6
-
72
-
-
57549094368
-
The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice
-
Sou YS, Waguri S, Iwata J, et al. The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice. Mol Biol Cell 2008; 19:4762-4775.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 4762-4775
-
-
Sou, Y.S.1
Waguri, S.2
Iwata, J.3
-
73
-
-
73949083594
-
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
-
Saitoh T, Fujita N, Hayashi T, et al. Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Proc Natl Acad Sci USA 2009; 106:20842-20846.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20842-20846
-
-
Saitoh, T.1
Fujita, N.2
Hayashi, T.3
-
74
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh T, Fujita N, Jang MH, et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 2008; 456:264-268.
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
-
75
-
-
51649124519
-
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
-
Kundu M, Lindsten T, Yang CY, et al. Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. Blood 2008; 112:1493-1502.
-
(2008)
Blood
, vol.112
, pp. 1493-1502
-
-
Kundu, M.1
Lindsten, T.2
Yang, C.Y.3
-
76
-
-
11144245626
-
The role of autophagy during the early neonatal starvation period
-
DOI 10.1038/nature03029
-
Kuma A, Hatano M, Matsui M, et al. The role of autophagy during the early neonatal starvation period. Nature 2004; 432:1032-1036. (Pubitemid 40052234)
-
(2004)
Nature
, vol.432
, Issue.7020
, pp. 1032-1036
-
-
Kuma, A.1
Hatano, M.2
Matsui, M.3
Yamamoto, A.4
Nakaya, H.5
Yoshimori, T.6
Ohsumi, Y.7
Tokuhisa, T.8
Mizushima, N.9
-
77
-
-
77953744638
-
Nonredundant role of Atg7 in mitochondrial clearance during erythroid development
-
Mortensen M, Simon AK. Nonredundant role of Atg7 in mitochondrial clearance during erythroid development. Autophagy 2010; 6:423-425.
-
(2010)
Autophagy
, vol.6
, pp. 423-425
-
-
Mortensen, M.1
Simon, A.K.2
-
78
-
-
64249123646
-
Autophagy is essential for mitochondrial clearance in mature T lymphocytes
-
Pua HH, Guo J, Komatsu M, He YW. Autophagy is essential for mitochondrial clearance in mature T lymphocytes. J Immunol 2009; 182:4046-4055.
-
(2009)
J Immunol
, vol.182
, pp. 4046-4055
-
-
Pua, H.H.1
Guo, J.2
Komatsu, M.3
He, Y.W.4
-
79
-
-
73449117508
-
Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice
-
Baerga R, Zhang Y, Chen PH, Goldman S, Jin S. Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice. Autophagy 2009; 5:1118-1130.
-
(2009)
Autophagy
, vol.5
, pp. 1118-1130
-
-
Baerga, R.1
Zhang, Y.2
Chen, P.H.3
Goldman, S.4
Jin, S.5
-
80
-
-
79954583401
-
Autophagic degradation of mitochondria in white adipose tissue differentiation
-
Goldman SJ, Zhang Y, Jin S. Autophagic degradation of mitochondria in white adipose tissue differentiation. Antioxid Redox Signal 2011; 14:1971-1978.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 1971-1978
-
-
Goldman, S.J.1
Zhang, Y.2
Jin, S.3
-
81
-
-
73949124173
-
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
-
Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, Jin S. Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis. Proc Natl Acad Sci USA 2009; 106:19860-19865.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 19860-19865
-
-
Zhang, Y.1
Goldman, S.2
Baerga, R.3
Zhao, Y.4
Komatsu, M.5
Jin, S.6
-
82
-
-
74149087187
-
Autophagy impairment inhibits differentiation of glioma stem/progenitor cells
-
Zhao Y, Huang Q, Yang J, et al. Autophagy impairment inhibits differentiation of glioma stem/progenitor cells. Brain Res 2010; 1313:250-258.
-
(2010)
Brain Res
, vol.1313
, pp. 250-258
-
-
Zhao, Y.1
Huang, Q.2
Yang, J.3
-
83
-
-
39149111914
-
Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells
-
Zeng M, Zhou JN. Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells. Cell Signal 2008; 20:659-665.
-
(2008)
Cell Signal
, vol.20
, pp. 659-665
-
-
Zeng, M.1
Zhou, J.N.2
-
84
-
-
67649607465
-
Autophagy, immunity, and microbial adaptations
-
Deretic V, Levine B. Autophagy, immunity, and microbial adaptations. Cell Host Microbe 2009; 5:527-549.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 527-549
-
-
Deretic, V.1
Levine, B.2
-
85
-
-
8344247016
-
Autophagy defends cells against invading group A Streptococcus
-
DOI 10.1126/science.1103966
-
Nakagawa I, Amano A, Mizushima N, et al. Autophagy defends cells against invading group A Streptococcus. Science 2004; 306:1037-1040. (Pubitemid 39482907)
-
(2004)
Science
, vol.306
, Issue.5698
, pp. 1037-1040
-
-
Nakagawa, I.1
Amano, A.2
Mizushima, N.3
Yamamoto, A.4
Yamaguchi, H.5
Kamimoto, T.6
Nara, A.7
Funao, J.8
Nakata, M.9
Tsuda, K.10
Hamada, S.11
Yoshimori, T.12
-
86
-
-
13244256806
-
Escape of intracellular Shigella from autophagy
-
DOI 10.1126/science.1106036
-
Ogawa M, Yoshimori T, Suzuki T, Sagara H, Mizushima N, Sasakawa C. Escape of intracellular Shigella from autophagy. Science 2005; 307:727-731. (Pubitemid 40194643)
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 727-731
-
-
Ogawa, M.1
Yoshimori, T.2
Suzuki, T.3
Sagara, H.4
Mizushima, N.5
Sasakawa, C.6
-
87
-
-
10944253145
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
-
DOI 10.1016/j.cell.2004.11.038, PII S0092867404011067
-
Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004; 119:753-766. (Pubitemid 40017683)
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 753-766
-
-
Gutierrez, M.G.1
Master, S.S.2
Singh, S.B.3
Taylor, G.A.4
Colombo, M.I.5
Deretic, V.6
-
88
-
-
33744958258
-
Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole
-
DOI 10.1074/jbc.M509157200
-
Birmingham CL, Smith AC, Bakowski MA, Yoshimori T, Brumell JH. Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole. J Biol Chem 2006; 281:11374-11383. (Pubitemid 43855562)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.16
, pp. 11374-11383
-
-
Birmingham, C.L.1
Smith, A.C.2
Bakowski, M.A.3
Yoshimori, T.4
Brumell, J.H.5
-
89
-
-
47849094901
-
Autophagic control of listeria through intracellular innate immune recognition in drosophila
-
Yano T, Mita S, Ohmori H, et al. Autophagic control of listeria through intracellular innate immune recognition in drosophila. Nat Immunol 2008; 9:908-916.
-
(2008)
Nat Immunol
, vol.9
, pp. 908-916
-
-
Yano, T.1
Mita, S.2
Ohmori, H.3
-
90
-
-
33748331335
-
CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes
-
DOI 10.1172/JCI28796
-
Andrade RM, Wessendarp M, Gubbels MJ, Striepen B, Subauste CS. CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes. J Clin Invest 2006; 116:2366-2377. (Pubitemid 44330135)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.9
, pp. 2366-2377
-
-
Andrade, R.M.1
Wessendarp, M.2
Gubbels, M.-J.3
Striepen, B.4
Subauste, C.S.5
-
91
-
-
33644609471
-
PKR-dependent autophagic degradation of herpes simplex virus type 1
-
Talloczy Z, Virgin HWt, Levine B. PKR-dependent autophagic degradation of herpes simplex virus type 1. Autophagy 2006; 2:24-29.
-
(2006)
Autophagy
, vol.2
, pp. 24-29
-
-
Talloczy, Z.1
Virgin, H.W.T.2
Levine, B.3
-
92
-
-
0001488499
-
Protection against fatal sindbis virus encephalitis by Beclin, a novel Bcl-2-interacting protein
-
Liang XH, Kleeman LK, Jiang HH, et al. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J Virol 1998; 72:8586-8596. (Pubitemid 28471796)
-
(1998)
Journal of Virology
, vol.72
, Issue.11
, pp. 8586-8596
-
-
Liang, X.H.1
Kleeman, L.K.2
Jiang, H.H.3
Gordon, G.4
Goldman, J.E.5
Berry, G.6
Herman, B.7
Levine, B.8
-
93
-
-
19344368318
-
Autophagy regulates programmed cell death during the plant innate immune response
-
DOI 10.1016/j.cell.2005.03.007, PII S0092867405002400
-
Liu Y, Schiff M, Czymmek K, Talloczy Z, Levine B, Dinesh-Kumar SP. Autophagy regulates programmed cell death during the plant innate immune response. Cell 2005; 121:567-577. (Pubitemid 40720010)
-
(2005)
Cell
, vol.121
, Issue.4
, pp. 567-577
-
-
Liu, Y.1
Schiff, M.2
Czymmek, K.3
Talloczy, Z.4
Levine, B.5
Dinesh-Kumar, S.P.6
-
94
-
-
70350450808
-
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
-
Thurston TL, Ryzhakov G, Bloor S, von Muhlinen N, Randow F. The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat Immunol 2009; 10:1215-1221.
-
(2009)
Nat Immunol
, vol.10
, pp. 1215-1221
-
-
Thurston, T.L.1
Ryzhakov, G.2
Bloor, S.3
Von Muhlinen, N.4
Randow, F.5
-
95
-
-
74049126112
-
The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway
-
Zheng YT, Shahnazari S, Brech A, Lamark T, Johansen T, Brumell JH. The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway. J Immunol 2009; 183:5909-5916.
-
(2009)
J Immunol
, vol.183
, pp. 5909-5916
-
-
Zheng, Y.T.1
Shahnazari, S.2
Brech, A.3
Lamark, T.4
Johansen, T.5
Brumell, J.H.6
-
96
-
-
73649110275
-
Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide
-
Yu HB, Kielczewska A, Rozek A, et al. Sequestosome-1/p62 is the key intracellular target of innate defense regulator peptide. J Biol Chem 2009; 284:36007-36011.
-
(2009)
J Biol Chem
, vol.284
, pp. 36007-36011
-
-
Yu, H.B.1
Kielczewska, A.2
Rozek, A.3
-
97
-
-
33947715151
-
HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein
-
DOI 10.1016/j.chom.2006.12.001, PII S1931312807000029
-
Orvedahl A, Alexander D, Talloczy Z, et al. HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein. Cell Host Microbe 2007; 1:23-35. (Pubitemid 46506007)
-
(2007)
Cell Host and Microbe
, vol.1
, Issue.1
, pp. 23-35
-
-
Orvedahl, A.1
Alexander, D.2
Talloczy, Z.3
Sun, Q.4
Wei, Y.5
Zhang, W.6
Burns, D.7
Leib, D.A.8
Levine, B.9
-
98
-
-
67649585835
-
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
-
Kyei GB, Dinkins C, Davis AS, et al. Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J Cell Biol 2009; 186:255-268.
-
(2009)
J Cell Biol
, vol.186
, pp. 255-268
-
-
Kyei, G.B.1
Dinkins, C.2
Davis, A.S.3
-
99
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
DOI 10.1016/j.cell.2005.07.002, PII S0092867405006926
-
Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122:927-939. (Pubitemid 41345209)
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Xiao, H.L.5
Mizushima, N.6
Packer, M.7
Schneider, M.D.8
Levine, B.9
-
100
-
-
58149095737
-
Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11
-
Sinha S, Colbert CL, Becker N, Wei Y, Levine B. Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11. Autophagy 2008; 4:989-997.
-
(2008)
Autophagy
, vol.4
, pp. 989-997
-
-
Sinha, S.1
Colbert, C.L.2
Becker, N.3
Wei, Y.4
Levine, B.5
-
101
-
-
38049029041
-
Human cytomegalovirus controls a new autophagy-dependent cellular antiviral defense mechanism
-
Chaumorcel M, Souquere S, Pierron G, Codogno P, Esclatine A. Human cytomegalovirus controls a new autophagy-dependent cellular antiviral defense mechanism. Autophagy 2008; 4:46-53.
-
(2008)
Autophagy
, vol.4
, pp. 46-53
-
-
Chaumorcel, M.1
Souquere, S.2
Pierron, G.3
Codogno, P.4
Esclatine, A.5
-
102
-
-
57749100267
-
MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages
-
Shi CS, Kehrl JH. MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages. J Biol Chem 2008; 283:33175-33182.
-
(2008)
J Biol Chem
, vol.283
, pp. 33175-33182
-
-
Shi, C.S.1
Kehrl, J.H.2
-
103
-
-
77953858790
-
TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy
-
Shi CS, Kehrl JH. TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy. Sci Signal 2010; 3:ra42.
-
(2010)
Sci Signal
, vol.3
-
-
Shi, C.S.1
Kehrl, J.H.2
-
104
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, Carneiro LA, Ramjeet M, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 2010; 11:55-62.
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
-
105
-
-
34548700401
-
T Helper 2 Cytokines Inhibit Autophagic Control of Intracellular Mycobacterium tuberculosis
-
DOI 10.1016/j.immuni.2007.07.022, PII S1074761307004177
-
Harris J, De Haro SA, Master SS, et al. T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. Immunity 2007; 27:505-517. (Pubitemid 47418681)
-
(2007)
Immunity
, vol.27
, Issue.3
, pp. 505-517
-
-
Harris, J.1
De Haro, S.A.2
Master, S.S.3
Keane, J.4
Roberts, E.A.5
Delgado, M.6
Deretic, V.7
-
106
-
-
62449110463
-
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
-
Tal MC, Sasai M, Lee HK, Yordy B, Shadel GS, Iwasaki A. Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc Natl Acad Sci USA 2009; 106:2770-2775.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2770-2775
-
-
Tal, M.C.1
Sasai, M.2
Lee, H.K.3
Yordy, B.4
Shadel, G.S.5
Iwasaki, A.6
-
107
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira K, Haspel JA, Rathinam VA, et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 2011; 12:222-30.
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
-
108
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011; 469:221-225.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
109
-
-
79953176280
-
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
-
Harris J, Hartman M, Roche C, et al. Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. J Biol Chem 2011; 286:9587-9597.
-
(2011)
J Biol Chem
, vol.286
, pp. 9587-9597
-
-
Harris, J.1
Hartman, M.2
Roche, C.3
-
110
-
-
41449106674
-
The autophagy gene ATG5 plays an essential role in B lymphocyte development
-
Miller BC, Zhao Z, Stephenson LM, et al. The autophagy gene ATG5 plays an essential role in B lymphocyte development. Autophagy 2008; 4:309-314. (Pubitemid 351458091)
-
(2008)
Autophagy
, vol.4
, Issue.3
, pp. 309-314
-
-
Miller, B.C.1
Zhao, Z.2
Stephenson, L.M.3
Cadwell, K.4
Pua, H.H.5
Lee, H.K.6
Mizushima, N.7
Iwasaki, A.8
He, Y.-W.9
Swat, W.10
Virgin IV, H.W.11
-
111
-
-
33846461678
-
A critical role for the autophagy gene Atg5 in T cell survival and proliferation
-
DOI 10.1084/jem.20061303
-
Pua HH, Dzhagalov I, Chuck M, Mizushima N, He YW. A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J Exp Med 2007; 204:25-31. (Pubitemid 46148752)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.1
, pp. 25-31
-
-
Pua, H.H.1
Dzhagalov, I.2
Chuck, M.3
Mizushima, N.4
He, Y.-W.5
-
112
-
-
55949083821
-
FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells
-
Bell BD, Leverrier S, Weist BM, et al. FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells. Proc Natl Acad Sci USA 2008; 105:16677-16682.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16677-16682
-
-
Bell, B.D.1
Leverrier, S.2
Weist, B.M.3
-
113
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell K, Liu J Y, Brown SL, et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 2008; 456:259-263.
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
-
114
-
-
77955146917
-
Autophagy and adaptive immunity
-
Crotzer VL, Blum JS. Autophagy and adaptive immunity. Immunology 2010; 131:9-17.
-
(2010)
Immunology
, vol.131
, pp. 9-17
-
-
Crotzer, V.L.1
Blum, J.S.2
-
115
-
-
67349269904
-
Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection
-
English L, Chemali M, Duron J, et al. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat Immunol 2009; 10:480-487.
-
(2009)
Nat Immunol
, vol.10
, pp. 480-487
-
-
English, L.1
Chemali, M.2
Duron, J.3
-
116
-
-
76949091325
-
In vivo requirement for Atg5 in antigen presentation by dendritic cells
-
Lee HK, Mattei LM, Steinberg BE, et al. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity 2010; 32:227-239.
-
(2010)
Immunity
, vol.32
, pp. 227-239
-
-
Lee, H.K.1
Mattei, L.M.2
Steinberg, B.E.3
-
117
-
-
67549117101
-
Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells
-
Uhl M, Kepp O, Jusforgues-Saklani H, Vicencio JM, Kroemer G, Albert ML. Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells. Cell Death Differ 2009; 16:991-1005.
-
(2009)
Cell Death Differ
, vol.16
, pp. 991-1005
-
-
Uhl, M.1
Kepp, O.2
Jusforgues-Saklani, H.3
Vicencio, J.M.4
Kroemer, G.5
Albert, M.L.6
-
118
-
-
33947134377
-
Autophagy-dependent viral recognition by plasmacytoid dendritic cells
-
DOI 10.1126/science.1136880
-
Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 2007; 315:1398-1401. (Pubitemid 46399546)
-
(2007)
Science
, vol.315
, Issue.5817
, pp. 1398-1401
-
-
Lee, H.K.1
Lund, J.M.2
Ramanathan, B.3
Mizushima, N.4
Iwasaki, A.5
-
119
-
-
52149099867
-
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
-
Nedjic J, Aichinger M, Emmerich J, Mizushima N, Klein L. Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature 2008; 455:396-400.
-
(2008)
Nature
, vol.455
, pp. 396-400
-
-
Nedjic, J.1
Aichinger, M.2
Emmerich, J.3
Mizushima, N.4
Klein, L.5
-
121
-
-
57649149333
-
Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009
-
Kroemer G, Galluzzi L, Vandenabeele P, et al. Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 2009; 16:3-11.
-
(2009)
Cell Death Differ
, vol.16
, pp. 3-11
-
-
Kroemer, G.1
Galluzzi, L.2
Vandenabeele, P.3
-
122
-
-
77956172813
-
Physiological role of autophagy as an intracellular recycling system: With an emphasis on nutrient metabolism
-
Kuma A, Mizushima N. Physiological role of autophagy as an intracellular recycling system: with an emphasis on nutrient metabolism. Semin Cell Dev Biol 2010; 21:683-690.
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 683-690
-
-
Kuma, A.1
Mizushima, N.2
-
123
-
-
41449109334
-
Induction of autophagy during extracellular matrix detachment promotes cell survival
-
DOI 10.1091/mbc.E07-10-1092
-
Fung C, Lock R, Gao S, Salas E, Debnath J. Induction of autophagy during extracellular matrix detachment promotes cell survival. Mol Biol Cell 2008; 19:797-806. (Pubitemid 351481798)
-
(2008)
Molecular Biology of the Cell
, vol.19
, Issue.3
, pp. 797-806
-
-
Fung, C.1
Lock, R.2
Gao, S.3
Salas, E.4
Debnath, J.5
-
124
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
DOI 10.1016/j.cell.2004.11.046, PII S009286740401150X
-
Lum JJ, Bauer DE, Kong M, et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 2005; 120:237-248. (Pubitemid 40174766)
-
(2005)
Cell
, vol.120
, Issue.2
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
Harris, M.H.4
Li, C.5
Lindsten, T.6
Thompson, C.B.7
-
125
-
-
0842279780
-
Caspases function in autophagic programmed cell death in Drosophila
-
DOI 10.1242/dev.00933
-
Martin DN, Baehrecke EH. Caspases function in autophagic programmed cell death in Drosophila. Development 2004; 131:275-284. (Pubitemid 38181368)
-
(2004)
Development
, vol.131
, Issue.2
, pp. 275-284
-
-
Martin, D.N.1
Baehrecke, E.H.2
-
126
-
-
33746691954
-
Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
-
DOI 10.1172/JCI26185
-
Espert L, Denizot M, Grimaldi M, et al. Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. J Clin Invest 2006; 116:2161-2172. (Pubitemid 44162325)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.8
, pp. 2161-2172
-
-
Espert, L.1
Denizot, M.2
Grimaldi, M.3
Robert-Hebmann, V.4
Gay, B.5
Varbanov, M.6
Codogno, P.7
Biard-Piechaczyk, M.8
-
127
-
-
33745885329
-
DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis
-
DOI 10.1016/j.cell.2006.05.034, PII S0092867406007598
-
Crighton D, Wilkinson S, O'Prey J, et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006; 126:121-134. (Pubitemid 44040988)
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
Syed, N.4
Smith, P.5
Harrison, P.R.6
Gasco, M.7
Garrone, O.8
Crook, T.9
Ryan, K.M.10
-
128
-
-
77955903343
-
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
-
Nezis IP, Shravage BV, Sagona AP, et al. Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis. J Cell Biol 2010; 190:523-531.
-
(2010)
J Cell Biol
, vol.190
, pp. 523-531
-
-
Nezis, I.P.1
Shravage, B.V.2
Sagona, A.P.3
-
129
-
-
20144381544
-
Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death
-
Pyo JO, Jang MH, Kwon YK, et al. Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem 2005; 280:20722-20729.
-
(2005)
J Biol Chem
, vol.280
, pp. 20722-20729
-
-
Pyo, J.O.1
Jang, M.H.2
Kwon, Y.K.3
-
130
-
-
77951249136
-
Lysosome dysfunction triggers Atg7-dependent neural apoptosis
-
Walls KC, Ghosh AP, Franklin AV, et al. Lysosome dysfunction triggers Atg7-dependent neural apoptosis. J Biol Chem 2010; 285:10497-10507.
-
(2010)
J Biol Chem
, vol.285
, pp. 10497-10507
-
-
Walls, K.C.1
Ghosh, A.P.2
Franklin, A.V.3
-
131
-
-
79958276489
-
GX015-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy
-
Heidari N, Hicks MA, Harada H. GX015-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy. Cell Death Dis 2010; 1:e76.
-
(2010)
Cell Death Dis
, vol.1
-
-
Heidari, N.1
Hicks, M.A.2
Harada, H.3
-
132
-
-
77955637249
-
ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death
-
Radoshevich L, Murrow L, Chen N, et al. ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death. Cell 2010; 142:590-600.
-
(2010)
Cell
, vol.142
, pp. 590-600
-
-
Radoshevich, L.1
Murrow, L.2
Chen, N.3
-
133
-
-
33749162486
-
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
-
DOI 10.1038/ncb1482, PII NCB1482
-
Yousefi S, Perozzo R, Schmid I, et al. Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 2006; 8:1124-1132. (Pubitemid 44473608)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.10
, pp. 1124-1132
-
-
Yousefi, S.1
Perozzo, R.2
Schmid, I.3
Ziemiecki, A.4
Schaffner, T.5
Scapozza, L.6
Brunner, T.7
Simon, H.-U.8
-
134
-
-
75149171923
-
Control of basal autophagy by calpain1 mediated cleavage of ATG5
-
Xia HG, Zhang L, Chen G, et al. Control of basal autophagy by calpain1 mediated cleavage of ATG5. Autophagy 2010; 6:61-66.
-
(2010)
Autophagy
, vol.6
, pp. 61-66
-
-
Xia, H.G.1
Zhang, L.2
Chen, G.3
-
135
-
-
78649636176
-
Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
-
Wirawan E, Vandewalle L, Kersse K, et al. Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria. Cell Death Dis 2010; 1:e18.
-
(2010)
Cell Death Dis
, vol.1
-
-
Wirawan, E.1
Vandewalle, L.2
Kersse, K.3
-
136
-
-
69649090647
-
Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis
-
Betin VM, Lane JD. Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. J Cell Sci 2009; 122:2554-2566.
-
(2009)
J Cell Sci
, vol.122
, pp. 2554-2566
-
-
Betin, V.M.1
Lane, J.D.2
-
137
-
-
48249092267
-
Bcl-2 family members: Dual regulators of apoptosis and autophagy
-
Levine B, Sinha S, Kroemer G. Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 2008; 4:600-606.
-
(2008)
Autophagy
, vol.4
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, G.3
-
138
-
-
34249037565
-
L-beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
-
DOI 10.1074/jbc.M700492200
-
Oberstein A, Jeffrey PD, Shi Y. Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. J Biol Chem 2007; 282:13123-13132. (Pubitemid 47100641)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.17
, pp. 13123-13132
-
-
Oberstein, A.1
Jeffrey, P.D.2
Shi, Y.3
-
140
-
-
79953796695
-
Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy
-
Strappazzon F, Vietri-Rudan M, Campello S, et al. Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy. EMBO J 2011; 30:1195-1208.
-
(2011)
EMBO J
, vol.30
, pp. 1195-1208
-
-
Strappazzon, F.1
Vietri-Rudan, M.2
Campello, S.3
-
141
-
-
70449529788
-
FLIP-mediated autophagy regulation in cell death control
-
Lee JS, Li Q, Lee J Y, et al. FLIP-mediated autophagy regulation in cell death control. Nat Cell Biol 2009; 11:1355-1362.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1355-1362
-
-
Lee, J.S.1
Li, Q.2
Lee, J.Y.3
-
142
-
-
67650270918
-
Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL
-
Zalckvar E, Berissi H, Eisenstein M, Kimchi A. Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL. Autophagy 2009; 5:720-722.
-
(2009)
Autophagy
, vol.5
, pp. 720-722
-
-
Zalckvar, E.1
Berissi, H.2
Eisenstein, M.3
Kimchi, A.4
-
143
-
-
44949237240
-
JNK1-mediated phosphorylation of bcl-2 regulates starvation-induced autophagy
-
DOI 10.1016/j.molcel.2008.06.001, PII S1097276508003894
-
Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008; 30:678-688. (Pubitemid 351818252)
-
(2008)
Molecular Cell
, vol.30
, Issue.6
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
144
-
-
78650746461
-
Involvement of caspase-9 in autophagy-mediated cell survival pathway
-
Jeong HS, Choi HY, Lee ER, et al. Involvement of caspase-9 in autophagy-mediated cell survival pathway. Biochim Biophys Acta 2011; 1813:80-90.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 80-90
-
-
Jeong, H.S.1
Choi, H.Y.2
Lee, E.R.3
-
145
-
-
50249145608
-
A dual role of p53 in the control of autophagy
-
Tasdemir E, Chiara Maiuri M, Morselli E, et al. A dual role of p53 in the control of autophagy. Autophagy 2008; 4:810-814.
-
(2008)
Autophagy
, vol.4
, pp. 810-814
-
-
Tasdemir, E.1
Chiara Maiuri, M.2
Morselli, E.3
-
146
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
DOI 10.1038/ncb1730, PII NCB1730
-
Tasdemir E, Maiuri MC, Galluzzi L, et al. Regulation of autophagy by cytoplasmic p53. Nat cell biol 2008; 10:676-687. (Pubitemid 351772933)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.6
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.5
D'Amelio, M.6
Criollo, A.7
Morselli, E.8
Zhu, C.9
Harper, F.10
Nannmark, U.11
Samara, C.12
Pinton, P.13
Vicencio, J.M.14
Carnuccio, R.15
Moll, U.M.16
Madeo, F.17
Paterlini-Brechot, P.18
Rizzuto, R.19
Szabadkai, G.20
Pierron, G.21
Blomgren, K.22
Tavernarakis, N.23
Codogno, P.24
Cecconi, F.25
Kroemer, G.26
more..
-
147
-
-
20444363122
-
The coordinate regulation of the p53 and mTOR pathways in cells
-
DOI 10.1073/pnas.0502857102
-
Feng Z, Zhang H, Levine AJ, Jin S. The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci USA 2005; 102:8204-8209. (Pubitemid 40800067)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.23
, pp. 8204-8209
-
-
Feng, Z.1
Zhang, H.2
Levine, A.J.3
Jin, S.4
-
148
-
-
65549085701
-
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
-
Jin Z, Li Y, Pitti R, et al. Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell 2009; 137:721-735.
-
(2009)
Cell
, vol.137
, pp. 721-735
-
-
Jin, Z.1
Li, Y.2
Pitti, R.3
-
149
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K, Mathew R, Beaudoin B, et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006; 10:51-64.
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
-
150
-
-
34548434775
-
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
-
Suzuki T, Franchi L, Toma C, et al. Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages. PLoS Pathog 2007; 3:e111.
-
(2007)
PLoS Pathog
, vol.3
-
-
Suzuki, T.1
Franchi, L.2
Toma, C.3
-
151
-
-
37349037902
-
Autophagy is required for necrotic cell death in Caenorhabditis elegans
-
DOI 10.1038/sj.cdd.4402231, PII 4402231, Special issue on Tumor stress, cell death and the ensuing immune response
-
Samara C, Syntichaki P, Tavernarakis N. Autophagy is required for necrotic cell death in Caenorhabditis elegans. Cell Death Differ 2008; 15:105-112. (Pubitemid 350286178)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.1
, pp. 105-112
-
-
Samara, C.1
Syntichaki, P.2
Tavernarakis, N.3
-
152
-
-
77955865105
-
Inhibition of PI3k class III-dependent autophagy prevents apoptosis and necrosis by oxidative stress in dopaminergic neuroblastoma cells
-
Castino R, Bellio N, Follo C, Murphy D, Isidoro C. Inhibition of PI3k class III-dependent autophagy prevents apoptosis and necrosis by oxidative stress in dopaminergic neuroblastoma cells. Toxicol Sci 2010; 117:152-162.
-
(2010)
Toxicol Sci
, vol.117
, pp. 152-162
-
-
Castino, R.1
Bellio, N.2
Follo, C.3
Murphy, D.4
Isidoro, C.5
-
153
-
-
2642553881
-
Regulation of an ATG7-beclin 1 program of autophaglic cell death by caspase-8
-
DOI 10.1126/science.1096645
-
Yu L, Alva A, Su H, et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004; 304:1500-1502. (Pubitemid 38720930)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1500-1502
-
-
Yu, L.1
Alva, A.2
Su, H.3
Dutt, P.4
Freundt, E.5
Welsh, S.6
Baehrecke, E.H.7
Lenardo, M.J.8
-
154
-
-
33645521571
-
Autophagic programmed cell death by selective catalase degradation
-
Yu L, Wan F, Dutta S, et al. Autophagic programmed cell death by selective catalase degradation. Proc Natl Acad Sci USA 2006; 103:4952-4957.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 4952-4957
-
-
Yu, L.1
Wan, F.2
Dutta, S.3
-
155
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptopic programmed cell death dependent on autophagy genes
-
DOI 10.1038/ncb1192
-
Shimizu S, Kanaseki T, Mizushima N, et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004; 6:1221-1228. (Pubitemid 39625121)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.12
, pp. 1221-1228
-
-
Shimizu, S.1
Kanaseki, T.2
Mizushima, N.3
Mizuta, T.4
Arakawa-Kobayashi, S.5
Thompson, C.B.6
Tsujimoto, Y.7
-
156
-
-
38049123578
-
Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress
-
Ullman E, Fan Y, Stawowczyk M, Chen HM, Yue Z, Zong WX. Autophagy promotes necrosis in apoptosis-deficient cells in response to ER stress. Cell Death Differ 2008; 15:422-425.
-
(2008)
Cell Death Differ
, vol.15
, pp. 422-425
-
-
Ullman, E.1
Fan, Y.2
Stawowczyk, M.3
Chen, H.M.4
Yue, Z.5
Zong, W.X.6
-
157
-
-
33745864334
-
Deficiency in apoptotic effectors Bax and Bak reveals an autophagic cell death pathway initiated by photodamage to the endoplasmic reticulum
-
Buytaert E, Callewaert G, Vandenheede JR, Agostinis P. Deficiency in apoptotic effectors Bax and Bak reveals an autophagic cell death pathway initiated by photodamage to the endoplasmic reticulum. Autophagy 2006; 2:238-240. (Pubitemid 44030895)
-
(2006)
Autophagy
, vol.2
, Issue.3
, pp. 238-240
-
-
Buytaert, E.1
Callewaert, G.2
Vandenheede, J.R.3
Agostinis, P.4
-
158
-
-
77951171023
-
Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance
-
Bonapace L, Bornhauser BC, Schmitz M, et al. Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance. J Clin Invest 2010; 120:1310-1323.
-
(2010)
J Clin Invest
, vol.120
, pp. 1310-1323
-
-
Bonapace, L.1
Bornhauser, B.C.2
Schmitz, M.3
-
159
-
-
0033153320
-
The interaction of p62 with RIP links the atypical PKCs to NF-κB activation
-
DOI 10.1093/emboj/18.11.3044
-
Sanz L, Sanchez P, Lallena MJ, Diaz-Meco MT, Moscat J. The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation. EMBO J 1999; 18:3044-3053. (Pubitemid 29255613)
-
(1999)
EMBO Journal
, vol.18
, Issue.11
, pp. 3044-3053
-
-
Sanz, L.1
Sanchez, P.2
Lallena, M.-J.3
Diaz-Meco, M.T.4
Moscat, J.5
-
160
-
-
79651473201
-
Neutrophil extracellular trap cell death requires both autophagy and superoxide generation
-
Remijsen Q, Berghe TV, Wirawan E, et al. Neutrophil extracellular trap cell death requires both autophagy and superoxide generation. Cell Res 2011; 21:290-304.
-
(2011)
Cell Res
, vol.21
, pp. 290-304
-
-
Remijsen, Q.1
Berghe, T.V.2
Wirawan, E.3
-
162
-
-
33846210657
-
Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans
-
Jia K, Hart AC, Levine B. Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans. Autophagy 2007; 3:21-25. (Pubitemid 46100705)
-
(2007)
Autophagy
, vol.3
, Issue.1
, pp. 21-25
-
-
Jia, K.1
Hart, A.C.2
Levine, B.3
-
163
-
-
0141766912
-
Demography of dietary restriction and death in Drosophila
-
DOI 10.1126/science.1086016
-
Mair W, Goymer P, Pletcher SD, Partridge L. Demography of dietary restriction and death in Drosophila. Science 2003; 301:1731-1733. (Pubitemid 37174368)
-
(2003)
Science
, vol.301
, Issue.5640
, pp. 1731-1733
-
-
Mair, W.1
Goymer, P.2
Pletcher, S.D.3
Partridge, L.4
-
164
-
-
69449106873
-
Autophagy is required for extension of yeast chronological life span by rapamycin
-
Alvers AL, Wood MS, Hu D, Kaywell AC, Dunn WA Jr, Aris JP. Autophagy is required for extension of yeast chronological life span by rapamycin. Autophagy 2009; 5:847-849.
-
(2009)
Autophagy
, vol.5
, pp. 847-849
-
-
Alvers, A.L.1
Wood, M.S.2
Hu, D.3
Kaywell, A.C.4
Dunn Jr., W.A.5
Aris, J.P.6
-
165
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009; 460:392-395.
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
-
166
-
-
77950656808
-
Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol
-
Morselli E, Galluzzi L, Kepp O, et al. Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol. Aging 2009; 1:961-970.
-
(2009)
Aging
, vol.1
, pp. 961-970
-
-
Morselli, E.1
Galluzzi, L.2
Kepp, O.3
-
167
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
DOI 10.1038/nature02789
-
Wood JG, Rogina B, Lavu S, et al. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 2004; 430:686-689. (Pubitemid 39061685)
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 686-689
-
-
Wood, J.G.1
Regina, B.2
Lavu, S.3
Hewitz, K.4
Helfand, S.L.5
Tatar, M.6
Sinclair, D.7
-
168
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
DOI 10.1038/nature01960
-
Howitz KT, Bitterman KJ, Cohen HY, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003; 425:191-196. (Pubitemid 37150899)
-
(2003)
Nature
, vol.425
, Issue.6954
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.-L.10
Scherer, B.11
Sinclair, D.A.12
-
169
-
-
41549138483
-
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
-
DOI 10.1073/pnas.0712145105
-
Lee IH, Cao L, Mostoslavsky R, et al. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci USA 2008; 105:3374-3379. (Pubitemid 351723560)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.9
, pp. 3374-3379
-
-
In, H.L.1
Cao, L.2
Mostoslavsky, R.3
Lombard, D.B.4
Liu, J.5
Bruns, N.E.6
Tsokos, M.7
Alt, F.W.8
Finkel, T.9
-
170
-
-
75149128169
-
The life spanprolonging effect of sirtuin-1 is mediated by autophagy
-
Morselli E, Maiuri MC, Markaki M, et al. The life spanprolonging effect of sirtuin-1 is mediated by autophagy. Autophagy 2010; 6:186-188.
-
(2010)
Autophagy
, vol.6
, pp. 186-188
-
-
Morselli, E.1
Maiuri, M.C.2
Markaki, M.3
-
171
-
-
70449529855
-
Induction of autophagy by spermidine promotes longevity
-
Eisenberg T, Knauer H, Schauer A, et al. Induction of autophagy by spermidine promotes longevity. Nat Cell Biol 2009; 11:1305-1314.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1305-1314
-
-
Eisenberg, T.1
Knauer, H.2
Schauer, A.3
-
172
-
-
38449102148
-
Resveratrol induces proapoptotic endoplasmic reticulum stress in human colon cancer cells
-
Park JW, Woo KJ, Lee JT, et al. Resveratrol induces proapoptotic endoplasmic reticulum stress in human colon cancer cells. Oncol Rep 2007; 18:1269-1273.
-
(2007)
Oncol Rep
, vol.18
, pp. 1269-1273
-
-
Park, J.W.1
Woo, K.J.2
Lee, J.T.3
-
173
-
-
0029560552
-
The effect of age on formation and elimination of autophagic vacuoles in mouse hepatocytes
-
Terman A. The effect of age on formation and elimination of autophagic vacuoles in mouse hepatocytes. Gerontology 1995; 41 Suppl 2:319-326. (Pubitemid 26019927)
-
(1995)
Gerontology
, vol.41
, Issue.SUPPL. 2
, pp. 319-326
-
-
Terman, A.1
-
174
-
-
33745026738
-
Autophagy and aging: The importance of maintaining "clean," cells
-
Cuervo AM, Bergamini E, Brunk UT, Droge W, Ffrench M, Terman A. Autophagy and aging: the importance of maintaining "clean" cells. Autophagy 2005; 1:131-140.
-
(2005)
Autophagy
, vol.1
, pp. 131-140
-
-
Cuervo, A.M.1
Bergamini, E.2
Brunk, U.T.3
Droge, W.4
Ffrench, M.5
Terman, A.6
-
176
-
-
77953699668
-
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer
-
Dalby KN, Tekedereli I, Lopez-Berestein G, Ozpolat B. Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. Autophagy 2010; 6:322-329.
-
(2010)
Autophagy
, vol.6
, pp. 322-329
-
-
Dalby, K.N.1
Tekedereli, I.2
Lopez-Berestein, G.3
Ozpolat, B.4
-
178
-
-
79951847989
-
Principles and current strategies for targeting autophagy for cancer treatment
-
Amaravadi RK, Lippincott-Schwartz J, Yin XM, et al. Principles and current strategies for targeting autophagy for cancer treatment. Clin Cancer Res 2011; 17:654-666.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 654-666
-
-
Amaravadi, R.K.1
Lippincott-Schwartz, J.2
Yin, X.M.3
-
179
-
-
69949106925
-
The double-edged sword of autophagy modulation in cancer
-
White E, DiPaola RS. The double-edged sword of autophagy modulation in cancer. Clin Cancer Res 2009; 15:5308-5316.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5308-5316
-
-
White, E.1
DiPaola, R.S.2
-
180
-
-
19944434059
-
Inhibition of macroautophagy triggers apoptosis
-
DOI 10.1128/MCB.25.3.1025-1040.2005
-
Boya P, Gonzalez-Polo RA, Casares N, et al. Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol 2005; 25:1025-1040. (Pubitemid 40165810)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.3
, pp. 1025-1040
-
-
Boya, P.1
Gonzalez-Polo, R.-A.2
Casares, N.3
Perfettini, J.-L.4
Dessen, P.5
Larochette, N.6
Metivier, D.7
Meley, D.8
Souquere, S.9
Yoshimori, T.10
Pierron, G.11
Codogno, P.12
Kroemer, G.13
-
181
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
Guo JY, Chen HY, Mathew R, et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev 2011; 25:460-470.
-
(2011)
Genes Dev
, vol.25
, pp. 460-470
-
-
Guo, J.Y.1
Chen, H.Y.2
Mathew, R.3
-
182
-
-
79952229430
-
Pancreatic cancers require autophagy for tumor growth
-
Yang S, Wang X, Contino G, et al. Pancreatic cancers require autophagy for tumor growth. Genes Dev 2011; 25:717-729.
-
(2011)
Genes Dev
, vol.25
, pp. 717-729
-
-
Yang, S.1
Wang, X.2
Contino, G.3
-
183
-
-
77957681100
-
ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy
-
Dewaele M, Maes H, Agostinis P. ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy. Autophagy 2010; 6:838-854.
-
(2010)
Autophagy
, vol.6
, pp. 838-854
-
-
Dewaele, M.1
Maes, H.2
Agostinis, P.3
-
184
-
-
33846794896
-
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
-
DOI 10.1172/JCI28833
-
Amaravadi RK, Yu D, Lum JJ, et al. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J Clin Invest 2007; 117:326-336. (Pubitemid 46203961)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.2
, pp. 326-336
-
-
Amaravadi, R.K.1
Yu, D.2
Lum, J.J.3
Bui, T.4
Christophorou, M.A.5
Evan, G.I.6
Thomas-Tikhonenko, A.7
Thompson, C.B.8
-
185
-
-
77953289524
-
Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model
-
Li J, Hou N, Faried A, Tsutsumi S, Kuwano H. Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model. Eur J Cancer 2010; 46:1900-1909.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1900-1909
-
-
Li, J.1
Hou, N.2
Faried, A.3
Tsutsumi, S.4
Kuwano, H.5
-
186
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132:27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
187
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999; 402:672-676. (Pubitemid 129516338)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
188
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
Liang C, Feng P, Ku B, et al. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 2006; 8:688-699.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
-
189
-
-
0344142468
-
Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
-
DOI 10.1006/geno.1999.5851
-
Aita VM, Liang XH, Murty VV, et al. Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics 1999; 59:59-65. (Pubitemid 29339873)
-
(1999)
Genomics
, vol.59
, Issue.1
, pp. 59-65
-
-
Aita, V.M.1
Liang, X.H.2
Murty, V.V.V.S.3
Pincus, D.L.4
Yu, W.5
Cayanis, E.6
Kalachikov, S.7
Gilliam, T.C.8
Levine, B.9
-
190
-
-
34347404887
-
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
-
DOI 10.1101/gad.1565707
-
Karantza-Wadsworth V, Patel S, Kravchuk O, et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev 2007; 21:1621-1635. (Pubitemid 47026367)
-
(2007)
Genes and Development
, vol.21
, Issue.13
, pp. 1621-1635
-
-
Karantza-Wadsworth, V.1
Patel, S.2
Kravchuk, O.3
Chen, G.4
Mathew, R.5
Jin, S.6
White, E.7
-
191
-
-
34249863298
-
Autophagy suppresses tumor progression by limiting chromosomal instability
-
DOI 10.1101/gad.1545107
-
Mathew R, Kongara S, Beaudoin B, et al. Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev 2007; 21:1367-1381. (Pubitemid 46871040)
-
(2007)
Genes and Development
, vol.21
, Issue.11
, pp. 1367-1381
-
-
Mathew, R.1
Kongara, S.2
Beaudoin, B.3
Karp, C.M.4
Bray, K.5
Degenhardt, K.6
Chen, G.7
Jin, S.8
White, E.9
-
192
-
-
34249274942
-
Beclin 1 gene inhibits tumor growth in colon cancer cell lines
-
Koneri K, Goi T, Hirono Y, Katayama K, Yamaguchi A. Beclin 1 gene inhibits tumor growth in colon cancer cell lines. Anticancer Res 2007; 27:1453-1457. (Pubitemid 46807222)
-
(2007)
Anticancer Research
, vol.27
, Issue.3 B
, pp. 1453-1457
-
-
Koneri, K.1
Goi, T.2
Hirono, Y.3
Katayama, K.4
Yamaguchi, A.5
-
193
-
-
77949324323
-
Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells
-
Yoo BH, Wu X, Li Y, et al. Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells. J Biol Chem 2010; 285:5438-5449.
-
(2010)
J Biol Chem
, vol.285
, pp. 5438-5449
-
-
Yoo, B.H.1
Wu, X.2
Li, Y.3
-
194
-
-
34147161141
-
Tissue transglutaminase inhibits autophagy in pancreatic cancer cells
-
DOI 10.1158/1541-7786.MCR-06-0229
-
Akar U, Ozpolat B, Mehta K, Fok J, Kondo Y, Lopez-Berestein G. Tissue transglutaminase inhibits autophagy in pancreatic cancer cells. Mol Cancer Res 2007; 5:241-249. (Pubitemid 46569775)
-
(2007)
Molecular Cancer Research
, vol.5
, Issue.3
, pp. 241-249
-
-
Akar, U.1
Ozpolat, B.2
Mehta, K.3
Fok, J.4
Kondo, Y.5
Lopez-Berestein, G.6
-
195
-
-
48249087666
-
Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells
-
Akar U, Chaves-Reyez A, Barria M, et al. Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells. Autophagy 2008; 4:669-679.
-
(2008)
Autophagy
, vol.4
, pp. 669-679
-
-
Akar, U.1
Chaves-Reyez, A.2
Barria, M.3
-
196
-
-
33751034682
-
Aggregate-prone proteins are cleared from the cytosol by autophagy: Therapeutic implications
-
DOI 10.1016/S0070-2153(06)76003-3, PII S0070215306760033
-
Williams A, Jahreiss L, Sarkar S, et al. Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications. Curr Top Dev Biol 2006; 76:89-101. (Pubitemid 44760539)
-
(2006)
Current Topics in Developmental Biology
, vol.76
, pp. 89-101
-
-
Williams, A.1
Jahreiss, L.2
Sarkar, S.3
Saiki, S.4
Menzies, F.M.5
Ravikumar, B.6
Rubinsztein, D.C.7
-
197
-
-
77953139736
-
Fighting disease by selective autophagy of aggregate-prone proteins
-
Knaevelsrud H, Simonsen A. Fighting disease by selective autophagy of aggregate-prone proteins. FEBS Lett 2010; 584:2635-2645.
-
(2010)
FEBS Lett
, vol.584
, pp. 2635-2645
-
-
Knaevelsrud, H.1
Simonsen, A.2
-
198
-
-
70350550208
-
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases
-
Spencer B, Potkar R, Trejo M, et al. Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases. J Neurosci 2009; 29:13578-13588.
-
(2009)
J Neurosci
, vol.29
, pp. 13578-13588
-
-
Spencer, B.1
Potkar, R.2
Trejo, M.3
-
199
-
-
45749114895
-
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
-
DOI 10.1172/JCI33585
-
Pickford F, Masliah E, Britschgi M, et al. The autophagyrelated protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J Clin Invest 2008; 118:2190-2199. (Pubitemid 351872337)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.6
, pp. 2190-2199
-
-
Pickford, F.1
Masliah, E.2
Britschgi, M.3
Lucin, K.4
Narasimhan, R.5
Jaeger, P.A.6
Small, S.7
Spencer, B.8
Rockenstein, E.9
Levine, B.10
Wyss-Coray, T.11
-
200
-
-
77956215864
-
Regulation of amyloid precursor protein processing by the Beclin 1 complex
-
Jaeger PA, Pickford F, Sun CH, Lucin KM, Masliah E, Wyss-Coray T. Regulation of amyloid precursor protein processing by the Beclin 1 complex. PLoS One 2010; 5:e11102.
-
(2010)
PLoS One
, vol.5
-
-
Jaeger, P.A.1
Pickford, F.2
Sun, C.H.3
Lucin, K.M.4
Masliah, E.5
Wyss-Coray, T.6
-
202
-
-
77954486784
-
Laforin, the most common protein mutated in Lafora disease, regulates autophagy
-
Aguado C, Sarkar S, Korolchuk VI, et al. Laforin, the most common protein mutated in Lafora disease, regulates autophagy. Hum Mol Genet 2010; 19:2867-2876.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 2867-2876
-
-
Aguado, C.1
Sarkar, S.2
Korolchuk, V.I.3
-
203
-
-
33744916798
-
Regulation of intracellular accumulation of mutant huntingtin by beclin 1
-
DOI 10.1074/jbc.M600364200
-
Shibata M, Lu T, Furuya T, et al. Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1. J Biol Chem 2006; 281:14474-14485. (Pubitemid 43848378)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.20
, pp. 14474-14485
-
-
Shibata, M.1
Lu, T.2
Furuya, T.3
Degterev, A.4
Mizushima, N.5
Yoshimori, T.6
MacDonald, M.7
Yankner, B.8
Yuan, J.9
-
204
-
-
79955964504
-
Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain
-
Rohn TT, Wirawan E, Brown RJ, Harris JR, Masliah E, Vandenabeele P. Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain. Neurobiol Dis 2011; 43:68-78.
-
(2011)
Neurobiol Dis
, vol.43
, pp. 68-78
-
-
Rohn, T.T.1
Wirawan, E.2
Brown, R.J.3
Harris, J.R.4
Masliah, E.5
Vandenabeele, P.6
-
205
-
-
77956396747
-
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
-
Luciani A, Villella VR, Esposito S, et al. Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition. Nat Cell Biol 2010; 12:863-875.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 863-875
-
-
Luciani, A.1
Villella, V.R.2
Esposito, S.3
-
206
-
-
78149319082
-
Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration
-
Grumati P, Coletto L, Sabatelli P, et al. Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration. Nat Med 2010; 16:1313-1320.
-
(2010)
Nat Med
, vol.16
, pp. 1313-1320
-
-
Grumati, P.1
Coletto, L.2
Sabatelli, P.3
-
207
-
-
46449126749
-
Lysosomal myopathies: An excessive build-up in autopha-gosomes is too much to handle
-
Malicdan MC, Noguchi S, Nonaka I, Saftig P, Nishino I. Lysosomal myopathies: an excessive build-up in autopha-gosomes is too much to handle. Neuromuscul Disord 2008; 18:521-529.
-
(2008)
Neuromuscul Disord
, vol.18
, pp. 521-529
-
-
Malicdan, M.C.1
Noguchi, S.2
Nonaka, I.3
Saftig, P.4
Nishino, I.5
-
208
-
-
57649173518
-
The role of autophagy in the heart
-
Nishida K, Kyoi S, Yamaguchi O, Sadoshima J, Otsu K. The role of autophagy in the heart. Cell Death Differ 2009; 16:31-38.
-
(2009)
Cell Death Differ
, vol.16
, pp. 31-38
-
-
Nishida, K.1
Kyoi, S.2
Yamaguchi, O.3
Sadoshima, J.4
Otsu, K.5
-
209
-
-
17044440789
-
Primary LAMP-2 deficiency causes X-linked vacoular cardiomyopathy and myopathy (Danon disease)
-
DOI 10.1038/35022604
-
Nishino I, Fu J, Tanji K, et al. Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature 2000; 406:906-910. (Pubitemid 30664268)
-
(2000)
Nature
, vol.406
, Issue.6798
, pp. 906-910
-
-
Nishino, I.1
Fu, J.2
Tanji, K.3
Yamada, T.4
Shimojo, S.5
Koori, T.6
Mora, M.7
Riggs, J.E.8
Oh, S.J.9
Koga, Y.10
Sue, C.M.11
Yamamoto, A.12
Murakami, N.13
Shanske, S.14
Byrne, E.15
Bonilla, E.16
Honaka, I.17
DiMauro, S.18
Hirano, M.19
-
210
-
-
33744536558
-
Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury
-
DOI 10.1016/j.yjmcc.2006.03.428, PII S0022282806005190
-
Valentim L, Laurence KM, Townsend PA, et al. Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury. J Mol Cell Cardiol 2006; 40:846-852. (Pubitemid 43817043)
-
(2006)
Journal of Molecular and Cellular Cardiology
, vol.40
, Issue.6
, pp. 846-852
-
-
Valentim, L.1
Laurence, K.M.2
Townsend, P.A.3
Carroll, C.J.4
Soond, S.5
Scarabelli, T.M.6
Knight, R.A.7
Latchman, D.S.8
Stephanou, A.9
-
211
-
-
34147168105
-
Distinct roles of autophagy in the heart during ischemia and reperfusion: Roles of AMP-activated protein kinase and beclin 1 in mediating autophagy
-
DOI 10.1161/01.RES.0000261924.76669.36
-
Matsui Y, Takagi H, Qu X, et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ Res 2007; 100:914-922. (Pubitemid 46555697)
-
(2007)
Circulation Research
, vol.100
, Issue.6
, pp. 914-922
-
-
Matsui, Y.1
Takagi, H.2
Qu, X.3
Abdellatif, M.4
Sakoda, H.5
Asano, T.6
Levine, B.7
Sadoshima, J.8
-
212
-
-
78049498575
-
Alpha1-antitrypsin deficiency and autophagy
-
Marciniak SJ, Lomas DA. Alpha1-antitrypsin deficiency and autophagy. N Engl J Med 2010; 363:1863-1864.
-
(2010)
N Engl J Med
, vol.363
, pp. 1863-1864
-
-
Marciniak, S.J.1
Lomas, D.A.2
-
213
-
-
77954597127
-
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis
-
Hidvegi T, Ewing M, Hale P, et al. An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis. Science 2010; 329:229-232.
-
(2010)
Science
, vol.329
, pp. 229-232
-
-
Hidvegi, T.1
Ewing, M.2
Hale, P.3
-
214
-
-
77955292017
-
Role of autophagy in diabetes and mitochondria
-
Jung HS, Lee MS. Role of autophagy in diabetes and mitochondria. Ann N Y Acad Sci 2010; 1201:79-83.
-
(2010)
Ann N y Acad Sci
, vol.1201
, pp. 79-83
-
-
Jung, H.S.1
Lee, M.S.2
-
215
-
-
64549101639
-
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability
-
Kang MR, Kim MS, Oh JE, et al. Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. J Pathol 2009; 217:702-706.
-
(2009)
J Pathol
, vol.217
, pp. 702-706
-
-
Kang, M.R.1
Kim, M.S.2
Oh, J.E.3
-
216
-
-
77952272127
-
Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors
-
Li Z, Chen B, Wu Y, Jin F, Xia Y, Liu X. Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors. BMC Cancer 2010; 10:98.
-
(2010)
BMC Cancer
, vol.10
, pp. 98
-
-
Li, Z.1
Chen, B.2
Wu, Y.3
Jin, F.4
Xia, Y.5
Liu, X.6
-
217
-
-
34249825782
-
Somatic mutations of BECN1, an autophagy-related gene, in human cancers
-
DOI 10.1111/j.1600-0463.2007.apm-640.x
-
Lee JW, Jeong EG, Lee SH, Yoo NJ. Somatic mutations of BECN1, an autophagy-related gene, in human cancers. APMIS 2007; 115:750-756. (Pubitemid 46854994)
-
(2007)
APMIS
, vol.115
, Issue.6
, pp. 750-756
-
-
Lee, J.W.1
Jeong, E.G.2
Lee, S.H.3
Yoo, N.J.4
Lee, S.H.5
-
218
-
-
0036648240
-
Truncating mutations of RB1CC1 in human breast cancer
-
Chano T, Kontani K, Teramoto K, Okabe H, Ikegawa S. Truncating mutations of RB1CC1 in human breast cancer. Nat Genet 2002; 31:285-288.
-
(2002)
Nat Genet
, vol.31
, pp. 285-288
-
-
Chano, T.1
Kontani, K.2
Teramoto, K.3
Okabe, H.4
Ikegawa, S.5
-
219
-
-
78449273851
-
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
-
Knaevelsrud H, Ahlquist T, Merok MA, et al. UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy. Autophagy 2010; 6:863-870.
-
(2010)
Autophagy
, vol.6
, pp. 863-870
-
-
Knaevelsrud, H.1
Ahlquist, T.2
Merok, M.A.3
-
220
-
-
1242296021
-
Manipulation of nonsense mediated decay identifies gene mutations in colon cancer cells with microsatellite instability
-
DOI 10.1038/sj.onc.1207178
-
Ionov Y, Nowak N, Perucho M, Markowitz S, Cowell JK. Manipulation of nonsense mediated decay identifies gene mutations in colon cancer cells with microsatellite instability. Oncogene 2004; 23:639-645. (Pubitemid 38241265)
-
(2004)
Oncogene
, vol.23
, Issue.3
, pp. 639-645
-
-
Ionov, Y.1
Nowak, N.2
Perucho, M.3
Markowitz, S.4
Cowell, J.K.5
-
221
-
-
45049083880
-
Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability
-
Kim MS, Jeong EG, Ahn CH, Kim SS, Lee SH, Yoo NJ. Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability. Hum Pathol 2008; 39:1059-1063.
-
(2008)
Hum Pathol
, vol.39
, pp. 1059-1063
-
-
Kim, M.S.1
Jeong, E.G.2
Ahn, C.H.3
Kim, S.S.4
Lee, S.H.5
Yoo, N.J.6
|