메뉴 건너뛰기




Volumn 55, Issue 1, 2013, Pages 65-78

AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: A role for melatonin and trimetazidine cocktail

Author keywords

AMPK; Autophagy; Cold ischemia reperfusion injury; ER stress; IGL 1 preservation solution; Melatonin; Steatotic liver; Trimetazidine

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; AUTOPHAGY PROTEIN 7; BECLIN 1; CELL PROTEIN; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN 70; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INSTITUT GEORGES LOPEZ SOLUTION; LC3B PROTEIN; MELATONIN; PRESERVATION SOLUTION; PROTEIN KINASE; PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN KINASE R; PROTEIN P62; TRIMETAZIDINE; UNCLASSIFIED DRUG; UNIVERSITY OF WISCONSIN SOLUTION;

EID: 84885190019     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12051     Document Type: Article
Times cited : (95)

References (63)
  • 1
    • 0038487015 scopus 로고    scopus 로고
    • The utility of marginal donors in liver transplantation
    • BUSUTTIL RW, TANAKA K. The utility of marginal donors in liver transplantation. Liver Transpl 2003; 9:651-663.
    • (2003) Liver Transpl , vol.9 , pp. 651-663
    • Busuttil, R.W.1    Tanaka, K.2
  • 2
    • 79954708051 scopus 로고    scopus 로고
    • Liver transplantation using fatty livers: Always feasible?
    • MCCORMACK L, DUTKOWSKI P, EL-BADRY AM et al. Liver transplantation using fatty livers: always feasible? J Hepatol 2011; 54:1055-1062.
    • (2011) J Hepatol , vol.54 , pp. 1055-1062
    • McCormack, L.1    Dutkowski, P.2    El-Badry, A.M.3
  • 3
    • 0033646040 scopus 로고    scopus 로고
    • Mechanisms of ischemic injury are different in the steatotic and normal rat liver
    • SELZNER M, RUDIGER HA, SINDRAM D et al. Mechanisms of ischemic injury are different in the steatotic and normal rat liver. Hepatology 2000; 32:1280-1288.
    • (2000) Hepatology , vol.32 , pp. 1280-1288
    • Selzner, M.1    Rudiger, H.A.2    Sindram, D.3
  • 4
    • 0035087774 scopus 로고    scopus 로고
    • Fatty liver in liver transplantation and surgery
    • SELZNER M, CLAVIEN PA. Fatty liver in liver transplantation and surgery. Semin Liver Dis 2001; 21:105-113.
    • (2001) Semin Liver Dis , vol.21 , pp. 105-113
    • Selzner, M.1    Clavien, P.A.2
  • 6
    • 48949089843 scopus 로고    scopus 로고
    • Current studies on therapeutic approaches for ischemia/reperfusion injury in steatotic livers
    • XU C, YU C, LI Y. Current studies on therapeutic approaches for ischemia/reperfusion injury in steatotic livers. Hepatol Res 2008; 38:851-859.
    • (2008) Hepatol Res , vol.38 , pp. 851-859
    • Xu, C.1    Yu, C.2    Li, Y.3
  • 7
    • 33749348546 scopus 로고    scopus 로고
    • Past and future approaches to ischemia-reperfusion lesion associated with liver transplantation
    • CASILLAS-RAMIREZ A, MOSBAH IB, RAMALHO F et al. Past and future approaches to ischemia-reperfusion lesion associated with liver transplantation. Life Sci 2006; 79:1881-1894.
    • (2006) Life Sci , vol.79 , pp. 1881-1894
    • Casillas-Ramirez, A.1    Mosbah, I.B.2    Ramalho, F.3
  • 8
    • 79551483434 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts
    • ANDERSON CD, UPADHYA G, CONZEN KD et al. Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts. Liver Transpl 2011; 17:189-200.
    • (2011) Liver Transpl , vol.17 , pp. 189-200
    • Anderson, C.D.1    Upadhya, G.2    Conzen, K.D.3
  • 9
    • 79957948453 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress inhibition enhances liver tolerance to ischemia/reperfusion
    • PERALTA C, BRENNER C. Endoplasmic reticulum stress inhibition enhances liver tolerance to ischemia/reperfusion. Curr Med Chem 2011; 18:2016-2024.
    • (2011) Curr Med Chem , vol.18 , pp. 2016-2024
    • Peralta, C.1    Brenner, C.2
  • 10
    • 79958757918 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemiareperfusion
    • BEN MOSBAH I, ALFANY-FERNANDEZ I, MARTEL C et al. Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemiareperfusion. Cell Death Dis 2010; 1:e52.
    • (2010) Cell Death Dis , vol.1
    • Ben Mosbah, I.1    Alfany-Fernandez, I.2    Martel, C.3
  • 11
    • 70349575224 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: An unrecognized actor in solid organ transplantation
    • PALLET N, FOUGERAY S, BEAUNE P et al. Endoplasmic reticulum stress: an unrecognized actor in solid organ transplantation. Transplantation 2009; 88:605-613.
    • (2009) Transplantation , vol.88 , pp. 605-613
    • Pallet, N.1    Fougeray, S.2    Beaune, P.3
  • 12
    • 84859351533 scopus 로고    scopus 로고
    • IGL-1 solution reduces endoplasmic reticulum stress and apoptosis in rat liver transplantation
    • MOSBAH IB, ZAOUALI MA, MARTEL C et al. IGL-1 solution reduces endoplasmic reticulum stress and apoptosis in rat liver transplantation. Cell Death Dis 2012; 3:e279.
    • (2012) Cell Death Dis , vol.3
    • Mosbah, I.B.1    Zaouali, M.A.2    Martel, C.3
  • 13
    • 77956400005 scopus 로고    scopus 로고
    • Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance
    • YANG L, LI P, FU S et al. Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab 2010; 11:467-478.
    • (2010) Cell Metab , vol.11 , pp. 467-478
    • Yang, L.1    Li, P.2    Fu, S.3
  • 15
    • 68349136834 scopus 로고    scopus 로고
    • Impaired autophagic clearance after cold preservation of fatty livers correlates with tissue necrosis upon reperfusion and is reversed by hypothermic reconditioning
    • MINOR T, STEGEMANN J, HIRNER A et al. Impaired autophagic clearance after cold preservation of fatty livers correlates with tissue necrosis upon reperfusion and is reversed by hypothermic reconditioning. Liver Transpl 2009; 15:798-805.
    • (2009) Liver Transpl , vol.15 , pp. 798-805
    • Minor, T.1    Stegemann, J.2    Hirner, A.3
  • 16
  • 17
    • 79959997977 scopus 로고    scopus 로고
    • Ischemic preconditioning induces autophagy and limits necrosis in human recipients of fatty liver grafts, decreasing the incidence of rejection episodes
    • DEGLI ESPOSTI D, SEBAGH M, PHAM P et al. Ischemic preconditioning induces autophagy and limits necrosis in human recipients of fatty liver grafts, decreasing the incidence of rejection episodes. Cell Death Dis 2011; 2:e111.
    • (2011) Cell Death Dis , vol.2
    • Degli Esposti, D.1    Sebagh, M.2    Pham, P.3
  • 19
    • 77955107132 scopus 로고    scopus 로고
    • Hypoxia inducible factor-1alpha accumulation in steatotic liver preservation: Role of nitric oxide
    • ZAOUALI MA, BEN MOSBAH I, BONCOMPAGNI E et al. Hypoxia inducible factor-1alpha accumulation in steatotic liver preservation: role of nitric oxide. World J Gastroenterol 2010; 16:3499-3509.
    • (2010) World J Gastroenterol , vol.16 , pp. 3499-3509
    • Zaouali, M.A.1    Ben Mosbah, I.2    Boncompagni, E.3
  • 20
    • 79951625166 scopus 로고    scopus 로고
    • Melatonin protects steatotic and nonsteatotic liver grafts against cold ischemia and reperfusion injury
    • ZAOUALI MA, REITER RJ, PADRISSA-ALTES S et al. Melatonin protects steatotic and nonsteatotic liver grafts against cold ischemia and reperfusion injury. J Pineal Res 2011; 50:213-221.
    • (2011) J Pineal Res , vol.50 , pp. 213-221
    • Zaouali, M.A.1    Reiter, R.J.2    Padrissa-Altes, S.3
  • 21
    • 78649849920 scopus 로고    scopus 로고
    • Insulin like growth factor-1 increases fatty liver preservation in IGL-1 solution
    • ZAOUALI MA, PADRISSA-ALTES S, BEN MOSBAH I et al. Insulin like growth factor-1 increases fatty liver preservation in IGL-1 solution. World J Gastroenterol 2010; 16:5693-5700.
    • (2010) World J Gastroenterol , vol.16 , pp. 5693-5700
    • Zaouali, M.A.1    Padrissa-Altes, S.2    Ben Mosbah, I.3
  • 22
    • 67650475370 scopus 로고    scopus 로고
    • Melatonin - A pleiotropic molecule involved in pathophysiological processes following organ transplantation
    • FILDES JE, YONAN N, KEEVIL BG. Melatonin-a pleiotropic molecule involved in pathophysiological processes following organ transplantation. Immunology 2009; 127:443-449.
    • (2009) Immunology , vol.127 , pp. 443-449
    • Fildes, J.E.1    Yonan, N.2    Keevil, B.G.3
  • 23
    • 79954419394 scopus 로고    scopus 로고
    • The use of high-dose melatonin in liver resection is safe: First clinical experience
    • NICKKHOLGH A, SCHNEIDER H, SOBIREY M et al. The use of high-dose melatonin in liver resection is safe: first clinical experience. J Pineal Res 2011; 50:381-388.
    • (2011) J Pineal Res , vol.50 , pp. 381-388
    • Nickkholgh, A.1    Schneider, H.2    Sobirey, M.3
  • 24
    • 1642562820 scopus 로고    scopus 로고
    • Regulation of antioxidant enzymes: A significant role for melatonin
    • RODRIGUEZ C, MAYO JC, SAINZ RM et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res 2004; 36:1-9.
    • (2004) J Pineal Res , vol.36 , pp. 1-9
    • Rodriguez, C.1    Mayo, J.C.2    Sainz, R.M.3
  • 25
    • 84866264682 scopus 로고    scopus 로고
    • Melatonin attenuates inflammation and promotes regeneration in rabbits with fulminant hepatitis of viral origin
    • LALIENA A, SAN MIGUEL B, CRESPO I et al. Melatonin attenuates inflammation and promotes regeneration in rabbits with fulminant hepatitis of viral origin. J Pineal Res 2012; 53:270-278.
    • (2012) J Pineal Res , vol.53 , pp. 270-278
    • Laliena, A.1    San Miguel, B.2    Crespo, I.3
  • 26
    • 79960380554 scopus 로고    scopus 로고
    • Melatonin as a natural ally against oxidative stress: A physicochemical examination
    • GALANO A, TAN DX, REITER RJ. Melatonin as a natural ally against oxidative stress: a physicochemical examination. J Pineal Res 2011; 51:1-16.
    • (2011) J Pineal Res , vol.51 , pp. 1-16
    • Galano, A.1    Tan, D.X.2    Reiter, R.J.3
  • 27
    • 80051665420 scopus 로고    scopus 로고
    • Melatonin reduces lipid peroxidation and apoptotic-like changes in stallion spermatozoa
    • da SILVA CM, MACIAS-GARCIA B, MIRO-MORAN A et al. Melatonin reduces lipid peroxidation and apoptotic-like changes in stallion spermatozoa. J Pineal Res 2011; 51:172-179.
    • (2011) J Pineal Res , vol.51 , pp. 172-179
    • Da Silva, C.M.1    Macias-Garcia, B.2    Miro-Moran, A.3
  • 28
    • 83555166114 scopus 로고    scopus 로고
    • Melatonin attenuates decrease of protein phosphatase 2A subunit B in ischemic brain injury
    • KOH PO. Melatonin attenuates decrease of protein phosphatase 2A subunit B in ischemic brain injury. J Pineal Res 2012; 52:57-61.
    • (2012) J Pineal Res , vol.52 , pp. 57-61
    • Koh, P.O.1
  • 29
    • 84863560234 scopus 로고    scopus 로고
    • Melatonin inhibits type 1 interferon signaling of toll-like receptor 4 via heme oxygenase-1 induction in hepatic ischemia/reperfusion
    • KANG JW, LEE SM. Melatonin inhibits type 1 interferon signaling of toll-like receptor 4 via heme oxygenase-1 induction in hepatic ischemia/reperfusion. J Pineal Res 2012; 53:67-76.
    • (2012) J Pineal Res , vol.53 , pp. 67-76
    • Kang, J.W.1    Lee, S.M.2
  • 30
    • 22844452666 scopus 로고    scopus 로고
    • Exogenous melatonin enhances bile flow and ATP levels after cold storage and reperfusion in rat liver: Implications for liver transplantation
    • VAIRETTI M, FERRIGNO A, BERTONE R et al. Exogenous melatonin enhances bile flow and ATP levels after cold storage and reperfusion in rat liver: implications for liver transplantation. J Pineal Res 2005; 38:223-230.
    • (2005) J Pineal Res , vol.38 , pp. 223-230
    • Vairetti, M.1    Ferrigno, A.2    Bertone, R.3
  • 31
    • 33645762336 scopus 로고    scopus 로고
    • In situ demonstration of improvement of liver mitochondria function by melatonin after cold ischemia
    • FREITAS I, BERTONE V, GUARNASCHELLI C et al. In situ demonstration of improvement of liver mitochondria function by melatonin after cold ischemia. In Vivo 2006; 20:229-237.
    • (2006) Vivo , vol.20 , pp. 229-237
    • Freitas, I.1    Bertone, V.2    Guarnaschelli, C.3
  • 32
    • 33645055643 scopus 로고    scopus 로고
    • Trimetazidine: Is it a promising drug for use in steatotic grafts?
    • BEN MOSBAH I, CASILLAS-RAMIREZ A, XAUS C et al. Trimetazidine: Is it a promising drug for use in steatotic grafts? World J Gastroenterol 2006; 12:908-914
    • (2006) World J Gastroenterol , vol.12 , pp. 908-914
    • Ben Mosbah, I.1    Casillas-Ramirez, A.2    Xaus, C.3
  • 33
    • 33947383092 scopus 로고    scopus 로고
    • Addition of adenosine monophosphate-activated protein kinase activators to University of Wisconsin solution: A way of protecting rat steatotic livers
    • BEN MOSBAH I, MASSIP-SALCEDO M, FERNANDEZ-MONTEIRO I et al. Addition of adenosine monophosphate-activated protein kinase activators to University of Wisconsin solution: a way of protecting rat steatotic livers. Liver Transpl 2007; 13:410-425.
    • (2007) Liver Transpl , vol.13 , pp. 410-425
    • Ben Mosbah, I.1    Massip-Salcedo, M.2    Fernandez-Monteiro, I.3
  • 34
    • 77955983382 scopus 로고    scopus 로고
    • AMP-activated protein kinase as a target for preconditioning in transplantation medicine
    • BOUMA HR, KETELAAR ME, YARD BA et al. AMP-activated protein kinase as a target for preconditioning in transplantation medicine. Transplantation 2010; 90:353-358.
    • (2010) Transplantation , vol.90 , pp. 353-358
    • Bouma, H.R.1    Ketelaar, M.E.2    Yard, B.A.3
  • 35
    • 34147168105 scopus 로고    scopus 로고
    • Distinct roles of autophagy in the heart during ischemia and reperfusion: Roles of AMPactivated protein kinase and Beclin 1 in mediating autophagy
    • MATSUI Y, TAKAGI H, QU X et al. Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMPactivated protein kinase and Beclin 1 in mediating autophagy. Circ Res 2007; 100:914-922.
    • (2007) Circ Res , vol.100 , pp. 914-922
    • Matsui, Y.1    Takagi, H.2    Qu, X.3
  • 36
    • 43949145630 scopus 로고    scopus 로고
    • The role of autophagy during ischemia/reperfusion
    • SADOSHIMA J. The role of autophagy during ischemia/reperfusion. Autophagy 2008; 4:402-403.
    • (2008) Autophagy , vol.4 , pp. 402-403
    • Sadoshima, J.1
  • 37
    • 27744579061 scopus 로고    scopus 로고
    • Adenosine monophosphate-activated protein kinase and nitric oxide in rat steatotic liver transplantation
    • CARRASCO-CHAUMEL E, ROSELLO-CATAFAU J, BARTRONS R et al. Adenosine monophosphate-activated protein kinase and nitric oxide in rat steatotic liver transplantation. J Hepatol 2005; 43:997-1006.
    • (2005) J Hepatol , vol.43 , pp. 997-1006
    • Carrasco-Chaumel, E.1    Rosello-Catafau, J.2    Bartrons, R.3
  • 38
    • 79958272650 scopus 로고    scopus 로고
    • Apoptosis and autophagy in cold preservation ischemia
    • TURKMEN K, MARTIN J, AKCAY A et al. Apoptosis and autophagy in cold preservation ischemia. Transplantation 2011; 91:1192-1197.
    • (2011) Transplantation , vol.91 , pp. 1192-1197
    • Turkmen, K.1    Martin, J.2    Akcay, A.3
  • 39
    • 68049103917 scopus 로고    scopus 로고
    • Activation and signaling by the AMP-activated protein kinase in endothelial cells
    • FISSLTHALER B, FLEMING I. Activation and signaling by the AMP-activated protein kinase in endothelial cells. Circ Res 2009; 105:114-127.
    • (2009) Circ Res , vol.105 , pp. 114-127
    • Fisslthaler, B.1    Fleming, I.2
  • 40
    • 0141960109 scopus 로고    scopus 로고
    • AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells
    • LEE M,HWANG JT, LEE HJ et al. AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells. J Biol Chem 2003; 278:39653-39661.
    • (2003) J Biol Chem , vol.278 , pp. 39653-39661
    • Lee Mhwang, J.T.1    Lee, H.J.2
  • 41
    • 40949088023 scopus 로고    scopus 로고
    • Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion
    • LOOR G, SCHUMACKER PT. Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion. Cell Death Differ 2008; 15:686-690.
    • (2008) Cell Death Differ , vol.15 , pp. 686-690
    • Loor, G.1    Schumacker, P.T.2
  • 42
    • 23744449508 scopus 로고    scopus 로고
    • HO-1 induction by HIF-1: A new mechanism for delayed cardioprotection?
    • DAWN B, BOLLI R. HO-1 induction by HIF-1: A new mechanism for delayed cardioprotection? Am J Physiol Heart Circ Physiol 2005; 289:H522-H524.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Dawn, B.1    Bolli, R.2
  • 43
    • 0035189594 scopus 로고    scopus 로고
    • Adenosine monophosphate-activated protein kinase mediates the protective effects of ischemic preconditioning on hepatic ischemia-reperfusion injury in the rat
    • PERALTA C, BARTRONS R, SERAFIN A et al. Adenosine monophosphate-activated protein kinase mediates the protective effects of ischemic preconditioning on hepatic ischemia-reperfusion injury in the rat. Hepatology 2001; 34:1164-1173.
    • (2001) Hepatology , vol.34 , pp. 1164-1173
    • Peralta, C.1    Bartrons, R.2    Serafin, A.3
  • 44
    • 33751243296 scopus 로고    scopus 로고
    • Melatonin abates liver ischemia/ reperfusion injury by improving the balance between nitric oxide and endothelin
    • ZHANG WH, LI JY, ZHOU Y. Melatonin abates liver ischemia/ reperfusion injury by improving the balance between nitric oxide and endothelin. Hepatobiliary Pancreat Dis Int 2006; 5:574-579.
    • (2006) Hepatobiliary Pancreat Dis Int , vol.5 , pp. 574-579
    • Zhang, W.H.1    Li, J.Y.2    Zhou, Y.3
  • 45
    • 3042511840 scopus 로고    scopus 로고
    • Role of Akt signaling in mitochondrial survival pathway triggered by hypoxic preconditioning
    • UCHIYAMA T, ENGELMAN RM, MAULIK N et al. Role of Akt signaling in mitochondrial survival pathway triggered by hypoxic preconditioning. Circulation 2004; 109:3042-3049.
    • (2004) Circulation , vol.109 , pp. 3042-3049
    • Uchiyama, T.1    Engelman, R.M.2    Maulik, N.3
  • 46
    • 73549099329 scopus 로고    scopus 로고
    • Hypoxic preconditioning reinforces HIF-alpha-dependent HSP70 signaling to reduce ischemic renal failure-induced renal tubular apoptosis and autophagy
    • YEH CH, HSU SP, YANG CC et al. Hypoxic preconditioning reinforces HIF-alpha-dependent HSP70 signaling to reduce ischemic renal failure-induced renal tubular apoptosis and autophagy. Life Sci 2010; 86:115-123.
    • (2010) Life Sci , vol.86 , pp. 115-123
    • Yeh, C.H.1    Hsu, S.P.2    Yang, C.C.3
  • 47
    • 33646497683 scopus 로고    scopus 로고
    • Heat shock proteins and mitogen-activated protein kinases in steatotic livers undergoing ischemia-reperfusion: Some answers
    • MASSIP-SALCEDO M, CASILLAS-RAMIREZ A, FRANCO-GOU R et al. Heat shock proteins and mitogen-activated protein kinases in steatotic livers undergoing ischemia-reperfusion: some answers. Am J Pathol 2006; 168:1474-1485.
    • (2006) Am J Pathol , vol.168 , pp. 1474-1485
    • Massip-Salcedo, M.1    Casillas-Ramirez, A.2    Franco-Gou, R.3
  • 48
    • 84855475121 scopus 로고    scopus 로고
    • The multiple functions of heme oxygenase-1 in the liver
    • SASS G, BARIKBIN R, TIEGS G. The multiple functions of heme oxygenase-1 in the liver. Z Gastroenterol 2012; 50:34-40.
    • (2012) Z Gastroenterol , vol.50 , pp. 34-40
    • Sass, G.1    Barikbin, R.2    Tiegs, G.3
  • 49
    • 0036240068 scopus 로고    scopus 로고
    • Extended preservation of rat liver graft by induction of heme oxygenase-1
    • REDAELLI CA, TIAN YH, SCHAFFNER T et al. Extended preservation of rat liver graft by induction of heme oxygenase-1. Hepatology 2002; 35:1082-1092.
    • (2002) Hepatology , vol.35 , pp. 1082-1092
    • Redaelli, C.A.1    Tian, Y.H.2    Schaffner, T.3
  • 50
    • 0037180940 scopus 로고    scopus 로고
    • Heme oxygenase-1 overexpression protects rat hearts from cold ischemia/reperfusion injury via an antiapoptotic pathway
    • KATORI M, BUELOW R, KE B et al. Heme oxygenase-1 overexpression protects rat hearts from cold ischemia/reperfusion injury via an antiapoptotic pathway. Transplantation 2002; 73:287-292.
    • (2002) Transplantation , vol.73 , pp. 287-292
    • Katori, M.1    Buelow, R.2    Ke, B.3
  • 53
    • 34447558382 scopus 로고    scopus 로고
    • Melatonin attenuates arsenite-induced apoptosis in rat brain: Involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of alpha-synuclein
    • LIN AM, FANG SF, CHAO PL et al. Melatonin attenuates arsenite-induced apoptosis in rat brain: involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of alpha-synuclein. J Pineal Res 2007; 43:163-171.
    • (2007) J Pineal Res , vol.43 , pp. 163-171
    • Lin, A.M.1    Fang, S.F.2    Chao, P.L.3
  • 54
    • 27144489669 scopus 로고    scopus 로고
    • AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress
    • TERAI K, HIRAMOTO Y, MASAKI M et al. AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress. Mol Cell Biol 2005; 25:9554-9575.
    • (2005) Mol Cell Biol , vol.25 , pp. 9554-9575
    • Terai, K.1    Hiramoto, Y.2    Masaki, M.3
  • 55
    • 79953284583 scopus 로고    scopus 로고
    • AMP-activated protein kinase activation during cardioplegia-induced hypoxia/reoxygenation injury attenuates cardiomyocytic apoptosis via reduction of endoplasmic reticulum stress
    • YEH CH, CHEN TP, WANG YC et al. AMP-activated protein kinase activation during cardioplegia-induced hypoxia/reoxygenation injury attenuates cardiomyocytic apoptosis via reduction of endoplasmic reticulum stress. Mediators Inflamm 2010; 2010:130636.
    • (2010) Mediators Inflamm , vol.2010 , pp. 130636
    • Yeh, C.H.1    Chen, T.P.2    Wang, Y.C.3
  • 56
    • 43949096967 scopus 로고    scopus 로고
    • Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes
    • KIM JS, NITTA T, MOHUCZY D et al. Impaired autophagy: a mechanism of mitochondrial dysfunction in anoxic rat hepatocytes. Hepatology 2008; 47:1725-1736.
    • (2008) Hepatology , vol.47 , pp. 1725-1736
    • Kim, J.S.1    Nitta, T.2    Mohuczy, D.3
  • 57
    • 43949114864 scopus 로고    scopus 로고
    • Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion
    • MATSUI Y, KYOI S, TAKAGI H et al. Molecular mechanisms and physiological significance of autophagy during myocardial ischemia and reperfusion. Autophagy 2008; 4:409-415.
    • (2008) Autophagy , vol.4 , pp. 409-415
    • Matsui, Y.1    Kyoi, S.2    Takagi, H.3
  • 58
    • 65949095803 scopus 로고    scopus 로고
    • Autophagy regulates lipid metabolism
    • SINGH R, KAUSHIK S, WANG Y et al. Autophagy regulates lipid metabolism. Nature 2009; 458:1131-1135.
    • (2009) Nature , vol.458 , pp. 1131-1135
    • Singh, R.1    Kaushik, S.2    Wang, Y.3
  • 59
    • 80052617116 scopus 로고    scopus 로고
    • Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression
    • INAMI Y, YAMASHINA S, IZUMI K et al. Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression. Biochem Biophys Res Commun 2011; 412:618-625.
    • (2011) Biochem Biophys Res Commun , vol.412 , pp. 618-625
    • Inami, Y.1    Yamashina, S.2    Izumi, K.3
  • 60
    • 84863889307 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy
    • EVANKOVICH J, ZHANG R, CARDINAL JS et al. Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy. Am J Physiol Gastrointest Liver Physiol 2012; 303:G189-G198.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.303
    • Evankovich, J.1    Zhang, R.2    Cardinal, J.S.3
  • 61
    • 43749108141 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-gamma during hepatic ischemia is age-dependent
    • SHIN T, KUBOKI S, HUBER N et al. Activation of peroxisome proliferator-activated receptor-gamma during hepatic ischemia is age-dependent. J Surg Res 2008; 147:200-205.
    • (2008) J Surg Res , vol.147 , pp. 200-205
    • Shin, T.1    Kuboki, S.2    Huber, N.3
  • 62
    • 81855221944 scopus 로고    scopus 로고
    • Autophagy suppresses age-dependent ischemia and reperfusion injury in livers of mice
    • 1412188-2199
    • WANG JH, AHN IS, FISCHER TD et al. Autophagy suppresses age-dependent ischemia and reperfusion injury in livers of mice. Gastroenterology 2011; 1412188-2199:e6.
    • (2011) Gastroenterology
    • Wang, J.H.1    Ahn, I.S.2    Fischer, T.D.3
  • 63
    • 84864347965 scopus 로고    scopus 로고
    • Role of melatonin in the regulation of autophagy and mitophagy: A review
    • COTO-MONTES A, BOGA JA, ROSALES-CORRAL S et al. Role of melatonin in the regulation of autophagy and mitophagy: a review. Mol Cell Endocrinol 2012; 361:12-23.
    • (2012) Mol Cell Endocrinol , vol.361 , pp. 12-23
    • Coto-Montes, A.1    Boga, J.A.2    Rosales-Corral, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.