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Volumn 18, Issue , 2014, Pages 148-162

Involvement of oxysterols in age-related diseases and ageing processes

Author keywords

Age related diseases; Ageing; Oxysterols

Indexed keywords

OXYSTEROL; CHOLESTEROL;

EID: 84908238928     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2014.09.006     Document Type: Review
Times cited : (164)

References (227)
  • 2
    • 84869748975 scopus 로고    scopus 로고
    • Role of ABC transporters in the pathogenesis of Alzheimer's disease
    • Abuznait A.H., Kaddoumi A. Role of ABC transporters in the pathogenesis of Alzheimer's disease. ACS Chem. Neurosci. 2012, 3:820-831.
    • (2012) ACS Chem. Neurosci. , vol.3 , pp. 820-831
    • Abuznait, A.H.1    Kaddoumi, A.2
  • 4
    • 21344469049 scopus 로고    scopus 로고
    • 24S-hydroxycholesterol induces inflammatory gene expression in primary human neural cells
    • Alexandrov P., Cui J.G., Zhao Y., Lukiw W.J. 24S-hydroxycholesterol induces inflammatory gene expression in primary human neural cells. NeuroReport 2005, 16:909-913.
    • (2005) NeuroReport , vol.16 , pp. 909-913
    • Alexandrov, P.1    Cui, J.G.2    Zhao, Y.3    Lukiw, W.J.4
  • 5
    • 54849424320 scopus 로고    scopus 로고
    • Oxysterol-induced osteogenic differentiation of marrow stromal cells is regulated by Dkk-1 inhibitable and PI3-kinase mediated signaling
    • Amantea C.M., Kim W.K., Meliton V., Tetradis S., Parhami F. Oxysterol-induced osteogenic differentiation of marrow stromal cells is regulated by Dkk-1 inhibitable and PI3-kinase mediated signaling. J. Cell. Biochem. 2008, 105:424-436.
    • (2008) J. Cell. Biochem. , vol.105 , pp. 424-436
    • Amantea, C.M.1    Kim, W.K.2    Meliton, V.3    Tetradis, S.4    Parhami, F.5
  • 6
    • 79959599177 scopus 로고    scopus 로고
    • Alzheimer's disease as homeostatic responses to age-related myelin breakdown
    • Bartzokis G. Alzheimer's disease as homeostatic responses to age-related myelin breakdown. Neurobiol. Aging 2011, 32:1341-1371.
    • (2011) Neurobiol. Aging , vol.32 , pp. 1341-1371
    • Bartzokis, G.1
  • 8
    • 0014384685 scopus 로고
    • Formation and metabolism of 3-beta-hydroxycholest-5-en-7-one and cholest-5-ene-3-beta, 7-beta-diol Bile acids and steroids 192
    • Björkhem I., Einarsson K., Johansson G. Formation and metabolism of 3-beta-hydroxycholest-5-en-7-one and cholest-5-ene-3-beta, 7-beta-diol Bile acids and steroids 192. Acta Chem. Scand. 1968, 22:1594-1605.
    • (1968) Acta Chem. Scand. , vol.22 , pp. 1594-1605
    • Björkhem, I.1    Einarsson, K.2    Johansson, G.3
  • 9
    • 0031848338 scopus 로고    scopus 로고
    • Cholesterol homeostasis in human brain: turnover of 24Shydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation
    • Björkhem I., Lütjohann D., Diczfalusy U., Ståhle L., Ahlborg G., Wahren J. Cholesterol homeostasis in human brain: turnover of 24Shydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. J. Lipid Res. 1998, 39:1594-1600.
    • (1998) J. Lipid Res. , vol.39 , pp. 1594-1600
    • Björkhem, I.1    Lütjohann, D.2    Diczfalusy, U.3    Ståhle, L.4    Ahlborg, G.5    Wahren, J.6
  • 10
  • 11
    • 33751096969 scopus 로고    scopus 로고
    • Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain
    • Björkhem I. Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain. J. Intern. Med. 2006, 260:493-508.
    • (2006) J. Intern. Med. , vol.260 , pp. 493-508
    • Björkhem, I.1
  • 12
    • 66349136255 scopus 로고    scopus 로고
    • Are side-chain oxidized oxysterols regulators also in vivo?
    • Björkhem I. Are side-chain oxidized oxysterols regulators also in vivo?. J. Lipid Res. 2009, 50:S213-S218.
    • (2009) J. Lipid Res. , vol.50 , pp. S213-S218
    • Björkhem, I.1
  • 14
    • 84896029025 scopus 로고    scopus 로고
    • Telomerase activation: a potential key modulator for human healthspan and longevity
    • Boccardi V., Paolisso G. Telomerase activation: a potential key modulator for human healthspan and longevity. Ageing Res. Rev. 2014, 15C:1-5.
    • (2014) Ageing Res. Rev. , vol.15 C , pp. 1-5
    • Boccardi, V.1    Paolisso, G.2
  • 15
    • 0029671454 scopus 로고    scopus 로고
    • Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
    • Bodovitz S., Klein W.L. Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J. Biol. Chem. 1996, 271:4436-4440.
    • (1996) J. Biol. Chem. , vol.271 , pp. 4436-4440
    • Bodovitz, S.1    Klein, W.L.2
  • 16
    • 0035856407 scopus 로고    scopus 로고
    • On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells
    • Bogdanovic N., Bretillon L., Lund E.G., Diczfalusy U., Lannfelt L., Winblad B., Russell D.W., Björkhem I. On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells. Neurosci. Lett. 2001, 314:45-48.
    • (2001) Neurosci. Lett. , vol.314 , pp. 45-48
    • Bogdanovic, N.1    Bretillon, L.2    Lund, E.G.3    Diczfalusy, U.4    Lannfelt, L.5    Winblad, B.6    Russell, D.W.7    Björkhem, I.8
  • 17
    • 17144454964 scopus 로고    scopus 로고
    • Insulin secretion in type 2 diabetes: clinical aspects
    • Boitard C. Insulin secretion in type 2 diabetes: clinical aspects. Diabetes Metab. 2002, 28. 4S33-4S38.
    • (2002) Diabetes Metab. , vol.28 , pp. 4S33-4S38
    • Boitard, C.1
  • 18
    • 84908228244 scopus 로고    scopus 로고
    • Evaluation de la toxicité de moules de la CÔte Atlantique Marocaine utilisées comme bioindicateurs de contamination: étude in vivo et in vitro sur des rongeurs et des cellules béta-pancréatiques murines (MIN-6)
    • University of Bourgogne, University of Settat, Dijon, France/Marocco, (Ph.D. Thesis)
    • Boumhras M. Evaluation de la toxicité de moules de la CÔte Atlantique Marocaine utilisées comme bioindicateurs de contamination: étude in vivo et in vitro sur des rongeurs et des cellules béta-pancréatiques murines (MIN-6) 2012, University of Bourgogne, University of Settat, Dijon, France/Marocco, (Ph.D. Thesis).
    • (2012)
    • Boumhras, M.1
  • 21
    • 0035088540 scopus 로고    scopus 로고
    • Cataract blindness-challenges for the 21st century
    • Brian G., Taylor H. Cataract blindness-challenges for the 21st century. Bull. World Health Organ. 2001, 79:249-256.
    • (2001) Bull. World Health Organ. , vol.79 , pp. 249-256
    • Brian, G.1    Taylor, H.2
  • 22
    • 0032890337 scopus 로고    scopus 로고
    • Oxysterols and atherosclerosis
    • Brown A.J., Jessup W. Oxysterols and atherosclerosis. Atherosclerosis 1999, 142:1-28.
    • (1999) Atherosclerosis , vol.142 , pp. 1-28
    • Brown, A.J.1    Jessup, W.2
  • 24
    • 67349270965 scopus 로고    scopus 로고
    • Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
    • Bu G. Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy. Nat. Rev. Neurosci. 2009, 10:333-344.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 333-344
    • Bu, G.1
  • 25
    • 0036452144 scopus 로고    scopus 로고
    • Cholesterol in Alzheimer's disease and tauopathy
    • Burns M., Duff.K. Cholesterol in Alzheimer's disease and tauopathy. Ann. N.Y. Acad. Sci. 2002, 977:367-375.
    • (2002) Ann. N.Y. Acad. Sci. , vol.977 , pp. 367-375
    • Burns, M.1    Duff, K.2
  • 27
    • 84861637114 scopus 로고    scopus 로고
    • Regulation of the expression of interleukin-8 induced by 25-hydroxycholesterol in retinal pigment epithelium cells
    • Catarino S., Bento C.F., Brito A., Murteira E., Fernandes A.F., Pereira P. Regulation of the expression of interleukin-8 induced by 25-hydroxycholesterol in retinal pigment epithelium cells. Acta Ophtalmol. 2012, 90:255-263.
    • (2012) Acta Ophtalmol. , vol.90 , pp. 255-263
    • Catarino, S.1    Bento, C.F.2    Brito, A.3    Murteira, E.4    Fernandes, A.F.5    Pereira, P.6
  • 28
    • 0030026343 scopus 로고    scopus 로고
    • Cholesterol and cataracts
    • Cenedella R.J. Cholesterol and cataracts. Surv. Ophthalmol. 1996, 40:320-337.
    • (1996) Surv. Ophthalmol. , vol.40 , pp. 320-337
    • Cenedella, R.J.1
  • 29
    • 13844255073 scopus 로고    scopus 로고
    • Cholesterol-3-beta, 5-alpha, 6-beta-triol induced genotoxicity through reactive oxygen species formation
    • Cheng Y.W., Kang J.J., Shih Y.L., Lo Y.L., Wang C.F. Cholesterol-3-beta, 5-alpha, 6-beta-triol induced genotoxicity through reactive oxygen species formation. Food Chem. Toxicol. 2005, 43:617-622.
    • (2005) Food Chem. Toxicol. , vol.43 , pp. 617-622
    • Cheng, Y.W.1    Kang, J.J.2    Shih, Y.L.3    Lo, Y.L.4    Wang, C.F.5
  • 30
    • 28444468904 scopus 로고    scopus 로고
    • Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy
    • Curcio C.A., Presley J.B., Malek G., Medeiros N.E., Avery D.V., Kruth H.S. Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy. Exp. Eye Res. 2005, 81:731-741.
    • (2005) Exp. Eye Res. , vol.81 , pp. 731-741
    • Curcio, C.A.1    Presley, J.B.2    Malek, G.3    Medeiros, N.E.4    Avery, D.V.5    Kruth, H.S.6
  • 31
    • 77956494238 scopus 로고    scopus 로고
    • The oxysterol 27-hydroxycholesterol increases beta-amyloid and oxidative stress in retinal pigment epithelial cells
    • Dasari B., Prasanthi J.R., Marwarha G., Singh B.B., Ghribi O. The oxysterol 27-hydroxycholesterol increases beta-amyloid and oxidative stress in retinal pigment epithelial cells. BMC Ophthalmol. 2010, 10:22.
    • (2010) BMC Ophthalmol. , vol.10 , pp. 22
    • Dasari, B.1    Prasanthi, J.R.2    Marwarha, G.3    Singh, B.B.4    Ghribi, O.5
  • 32
    • 80051795545 scopus 로고    scopus 로고
    • Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina
    • Dasari B., Prasanthi J.R., Marwarha G., Singh B.B., Ghribi O. Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina. BMC Ophthalmol. 2011, 11:22.
    • (2011) BMC Ophthalmol. , vol.11 , pp. 22
    • Dasari, B.1    Prasanthi, J.R.2    Marwarha, G.3    Singh, B.B.4    Ghribi, O.5
  • 36
    • 0031046475 scopus 로고    scopus 로고
    • Inhibitors of arterial relaxation among components of human oxidized low-density lipoproteins Cholesterol derivatives oxidized in position 7 are potent inhibitors of endothelium-dependent relaxation
    • Deckert V., Perségol L., Viens L., Lizard G., Athias A., Lallemant C., Gambert P., Lagrost L. Inhibitors of arterial relaxation among components of human oxidized low-density lipoproteins Cholesterol derivatives oxidized in position 7 are potent inhibitors of endothelium-dependent relaxation. Circulation 1997, 95:723-731.
    • (1997) Circulation , vol.95 , pp. 723-731
    • Deckert, V.1    Perségol, L.2    Viens, L.3    Lizard, G.4    Athias, A.5    Lallemant, C.6    Gambert, P.7    Lagrost, L.8
  • 37
    • 0036848043 scopus 로고    scopus 로고
    • The impairment of endothelium-dependent arterial relaxation by 7-ketocholesterol is associated with an early activation of protein kinase C
    • Deckert V., Duverneuil L., Poupon S., Monier S., Le Guern N., Lizard G., Masson D., Lagrost L. The impairment of endothelium-dependent arterial relaxation by 7-ketocholesterol is associated with an early activation of protein kinase C. Br. J. Pharmacol. 2002, 137:655-662.
    • (2002) Br. J. Pharmacol. , vol.137 , pp. 655-662
    • Deckert, V.1    Duverneuil, L.2    Poupon, S.3    Monier, S.4    Le Guern, N.5    Lizard, G.6    Masson, D.7    Lagrost, L.8
  • 40
    • 0037975774 scopus 로고    scopus 로고
    • Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas
    • Dentchev T., Milam A.H., Lee V.M., Trojanowski J.Q., Dunaief J.L. Amyloid-beta is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas. Mol. Vision 2003, 9:184-190.
    • (2003) Mol. Vision , vol.9 , pp. 184-190
    • Dentchev, T.1    Milam, A.H.2    Lee, V.M.3    Trojanowski, J.Q.4    Dunaief, J.L.5
  • 42
    • 79955051063 scopus 로고    scopus 로고
    • Linking lipids to Alzheimer's disease: cholesterol and beyond
    • Di Paolo G., Kim T.W. Linking lipids to Alzheimer's disease: cholesterol and beyond. Nat. Rev. Neurosci. 2011, 12:284-296.
    • (2011) Nat. Rev. Neurosci. , vol.12 , pp. 284-296
    • Di Paolo, G.1    Kim, T.W.2
  • 43
    • 84874115453 scopus 로고    scopus 로고
    • On the formation and possible biological role of 25-hydroxycholesterol
    • Diczfalusy U. On the formation and possible biological role of 25-hydroxycholesterol. Biochimie 2013, 95:455-460.
    • (2013) Biochimie , vol.95 , pp. 455-460
    • Diczfalusy, U.1
  • 44
    • 59849104241 scopus 로고    scopus 로고
    • Molecular pathology of age-related macular degeneration
    • Ding X., Patel M., Chan C.C. Molecular pathology of age-related macular degeneration. Prog. Retin. Eye. Res. 2009, 28:1-18.
    • (2009) Prog. Retin. Eye. Res. , vol.28 , pp. 1-18
    • Ding, X.1    Patel, M.2    Chan, C.C.3
  • 48
    • 79952202599 scopus 로고    scopus 로고
    • Ketocholesterol inhibits Na K-ATPase activity by decreasing expression of its α1-subunit and membrane fluidity in human endothelial cells
    • Duran M.J., Pierre S.V., Lesnik P., Pieroni G., Bourdeaux M., Dignat-Georges F., Sampol J., Maixent J.M. ketocholesterol inhibits Na K-ATPase activity by decreasing expression of its α1-subunit and membrane fluidity in human endothelial cells. Cell. Mol. Biol. 2010, 56:1434-1441.
    • (2010) Cell. Mol. Biol. , vol.56 , pp. 1434-1441
    • Duran, M.J.1    Pierre, S.V.2    Lesnik, P.3    Pieroni, G.4    Bourdeaux, M.5    Dignat-Georges, F.6    Sampol, J.7    Maixent, J.M.8
  • 50
    • 84867575586 scopus 로고    scopus 로고
    • Chronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood-brain barrier leakage in rats in vivo
    • Ehrlich D., Humpel C. Chronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood-brain barrier leakage in rats in vivo. J. Neurol. Sci. 2012, 322:92-95.
    • (2012) J. Neurol. Sci. , vol.322 , pp. 92-95
    • Ehrlich, D.1    Humpel, C.2
  • 51
    • 0037421206 scopus 로고    scopus 로고
    • Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
    • Ehehalt R., Keller P., Haass C., Thiele C., Simons K. Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts. J. Cell Biol. 2003, 160:113-123.
    • (2003) J. Cell Biol. , vol.160 , pp. 113-123
    • Ehehalt, R.1    Keller, P.2    Haass, C.3    Thiele, C.4    Simons, K.5
  • 52
    • 34249828178 scopus 로고    scopus 로고
    • Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway
    • Famer D., Meaney S., Mousavi M., Nordberg A., Bjorkhem I., Crisby M. Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway. Biochem. Biophys. Res. Commun. 2007, 359:46-50.
    • (2007) Biochem. Biophys. Res. Commun. , vol.359 , pp. 46-50
    • Famer, D.1    Meaney, S.2    Mousavi, M.3    Nordberg, A.4    Bjorkhem, I.5    Crisby, M.6
  • 54
    • 0001600711 scopus 로고
    • New concepts of human lenticular lipids and their possible role in cataract
    • Feldman G.L., Feldman L.S. New concepts of human lenticular lipids and their possible role in cataract. Invest. Ophtalmol. 1965, 4:162-166.
    • (1965) Invest. Ophtalmol. , vol.4 , pp. 162-166
    • Feldman, G.L.1    Feldman, L.S.2
  • 57
    • 15244360529 scopus 로고    scopus 로고
    • Normative estimates of cross-sectional and longitudinal brain volume decline in aging and AD
    • Fotenos A., Snyder A. Normative estimates of cross-sectional and longitudinal brain volume decline in aging and AD. Neurology 2005, 64:1032-1039.
    • (2005) Neurology , vol.64 , pp. 1032-1039
    • Fotenos, A.1    Snyder, A.2
  • 58
    • 84898808313 scopus 로고    scopus 로고
    • In vivo consequences of cholesterol-24S-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina
    • Fourgeux C., Martine L., Acar N., Bron A.M., Creuzot-Garcher C.P., Bretillon L. In vivo consequences of cholesterol-24S-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina. Biochem. Biophys. Res. Commun. 2014, 446:775-781.
    • (2014) Biochem. Biophys. Res. Commun. , vol.446 , pp. 775-781
    • Fourgeux, C.1    Martine, L.2    Acar, N.3    Bron, A.M.4    Creuzot-Garcher, C.P.5    Bretillon, L.6
  • 60
    • 84864032314 scopus 로고    scopus 로고
    • Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: a paradigm for multifactorial neurodegenerative diseases?
    • Galea E., Launay N., Portero-Otin M., Ruiz M., Pamplona R., Aubourg P., Ferrer I., Pujol A. Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: a paradigm for multifactorial neurodegenerative diseases?. Biochim. Biophys. Acta 2012, 1822:1475-1488.
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 1475-1488
    • Galea, E.1    Launay, N.2    Portero-Otin, M.3    Ruiz, M.4    Pamplona, R.5    Aubourg, P.6    Ferrer, I.7    Pujol, A.8
  • 62
    • 84860520259 scopus 로고    scopus 로고
    • GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease
    • Gao C., Hölscher C., Liu Y., Li L. GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease. Rev. Neurosci. 2011, 23:1-11.
    • (2011) Rev. Neurosci. , vol.23 , pp. 1-11
    • Gao, C.1    Hölscher, C.2    Liu, Y.3    Li, L.4
  • 64
    • 79960933719 scopus 로고    scopus 로고
    • Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: implications regarding the vulnerability of atherosclerotic lesions
    • Gargiulo S., Sottero B., Gamba P., Chiarpotto E., Poli G., Leonarduzzi G. Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: implications regarding the vulnerability of atherosclerotic lesions. Free Radic. Biol. Med. 2011, 51:844-855.
    • (2011) Free Radic. Biol. Med. , vol.51 , pp. 844-855
    • Gargiulo, S.1    Sottero, B.2    Gamba, P.3    Chiarpotto, E.4    Poli, G.5    Leonarduzzi, G.6
  • 65
    • 84903706776 scopus 로고    scopus 로고
    • Metalloproteinases and metalloproteinase inhibitors in age-related diseases
    • Gargiulo S., Gamba P., Poli G., Leonarduzzi G. Metalloproteinases and metalloproteinase inhibitors in age-related diseases. Curr. Pharm. Des. 2014, 20:2993-3018.
    • (2014) Curr. Pharm. Des. , vol.20 , pp. 2993-3018
    • Gargiulo, S.1    Gamba, P.2    Poli, G.3    Leonarduzzi, G.4
  • 66
    • 84880838774 scopus 로고    scopus 로고
    • B cell localization: regulation by EBI2 and its oxysterol ligand
    • Gatto D., Brink R. B cell localization: regulation by EBI2 and its oxysterol ligand. Trends Immunol. 2013, 34:336-341.
    • (2013) Trends Immunol. , vol.34 , pp. 336-341
    • Gatto, D.1    Brink, R.2
  • 67
    • 33645068185 scopus 로고    scopus 로고
    • Liver X receptors in cardiovascular and metabolic disease
    • Geyeregger R., Zeyda M., Stulnig T.M. Liver X receptors in cardiovascular and metabolic disease. Cell Mol. Life Sci. 2006, 63:524-539.
    • (2006) Cell Mol. Life Sci. , vol.63 , pp. 524-539
    • Geyeregger, R.1    Zeyda, M.2    Stulnig, T.M.3
  • 68
    • 33746299216 scopus 로고    scopus 로고
    • High cholesterol content in neurons increases BACE, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus
    • Ghribi O., Larsen B., Schrag M., Herman M.M. High cholesterol content in neurons increases BACE, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus. Exp. Neurol. 2006, 200:460-467.
    • (2006) Exp. Neurol. , vol.200 , pp. 460-467
    • Ghribi, O.1    Larsen, B.2    Schrag, M.3    Herman, M.M.4
  • 69
  • 72
    • 0142213542 scopus 로고    scopus 로고
    • The free radical theory of aging
    • Harman D. The free radical theory of aging. Antioxid. Redox Signal. 2003, 5:557-561.
    • (2003) Antioxid. Redox Signal. , vol.5 , pp. 557-561
    • Harman, D.1
  • 74
    • 84880616033 scopus 로고    scopus 로고
    • 7 Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B. Am
    • He C., Zhu H., Zhang W., Okon I., Wang Q., Li H., Le Y.Z., Xie Z. 7 Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B. Am. J. Pathol. 2013, 183:626-637.
    • (2013) J. Pathol. , vol.183 , pp. 626-637
    • He, C.1    Zhu, H.2    Zhang, W.3    Okon, I.4    Wang, Q.5    Li, H.6    Le, Y.Z.7    Xie, Z.8
  • 75
    • 84881234258 scopus 로고    scopus 로고
    • Fast LC-MS/MS analysis of free oxysterols derived from reactive oxygen species in human plasma and carotid plaque
    • Helmschrodt C., Becker S., Schröter J., Hecht M., Aust G., Thiery J., Ceglarek U. Fast LC-MS/MS analysis of free oxysterols derived from reactive oxygen species in human plasma and carotid plaque. Clin. Chim. Acta 2013, 425:3-8.
    • (2013) Clin. Chim. Acta , vol.425 , pp. 3-8
    • Helmschrodt, C.1    Becker, S.2    Schröter, J.3    Hecht, M.4    Aust, G.5    Thiery, J.6    Ceglarek, U.7
  • 78
    • 13444302715 scopus 로고    scopus 로고
    • Sequential roles of Hedgehog and Wnt signaling in osteoblast development
    • Hu H., Hilton M.J., Tu X., Yu K., Ornitz D.M., Long F. Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development 2005, 132:49-60.
    • (2005) Development , vol.132 , pp. 49-60
    • Hu, H.1    Hilton, M.J.2    Tu, X.3    Yu, K.4    Ornitz, D.M.5    Long, F.6
  • 79
    • 84862780347 scopus 로고    scopus 로고
    • Sterculic acid antagonizes 7-ketocholesterol-mediated inflammation and inhibits choroidal neovascularization
    • Huang J.D., Amaral J., Lee J.W., Larrayoz I.M., Rodriguez I.R. Sterculic acid antagonizes 7-ketocholesterol-mediated inflammation and inhibits choroidal neovascularization. Biochim. Biophys. Acta 2012, 1821:637-646.
    • (2012) Biochim. Biophys. Acta , vol.1821 , pp. 637-646
    • Huang, J.D.1    Amaral, J.2    Lee, J.W.3    Larrayoz, I.M.4    Rodriguez, I.R.5
  • 80
    • 74149083432 scopus 로고    scopus 로고
    • Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease
    • Hudry E., Van Dam D., Kulik W., De Deyn P.P., Stet F.S., Ahouansou O., Benraiss A., Delacourte A., Bougnères P., Aubourg P., Cartier N. Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease. Mol. Ther. 2010, 18:44-53.
    • (2010) Mol. Ther. , vol.18 , pp. 44-53
    • Hudry, E.1    Van Dam, D.2    Kulik, W.3    De Deyn, P.P.4    Stet, F.S.5    Ahouansou, O.6    Benraiss, A.7    Delacourte, A.8    Bougnères, P.9    Aubourg, P.10    Cartier, N.11
  • 81
    • 80051471752 scopus 로고    scopus 로고
    • Pathways of cholesterol oxidation via non-enzymatic mechanisms
    • Iuliano L. Pathways of cholesterol oxidation via non-enzymatic mechanisms. Chem. Phys. Lipids 2011, 164:457-468.
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 457-468
    • Iuliano, L.1
  • 82
    • 66549106850 scopus 로고    scopus 로고
    • Alzheimer's Disease Neuroimaging Initiative, Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease, implications for sequence of pathological events in Alzheimer's disease
    • Jack C.R., Lowe V.J., Weigand S.D., Wiste H.J., Senjem M.L., Knopman D.S., Shiung M.M., Gunter J.L., Boeve B.F., Kemp B.J., Weiner M., Petersen R.C. Alzheimer's Disease Neuroimaging Initiative, Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease, implications for sequence of pathological events in Alzheimer's disease. Brain 2009, 132:1355-1365.
    • (2009) Brain , vol.132 , pp. 1355-1365
    • Jack, C.R.1    Lowe, V.J.2    Weigand, S.D.3    Wiste, H.J.4    Senjem, M.L.5    Knopman, D.S.6    Shiung, M.M.7    Gunter, J.L.8    Boeve, B.F.9    Kemp, B.J.10    Weiner, M.11    Petersen, R.C.12
  • 84
    • 65549154386 scopus 로고    scopus 로고
    • The retinal oxysterol pathway: a unifying hypothesis for the cause of age-related macular degeneration
    • Javitt N.B., Javitt J.C. The retinal oxysterol pathway: a unifying hypothesis for the cause of age-related macular degeneration. Curr. Opin. Ophthalmol. 2009, 20:151-157.
    • (2009) Curr. Opin. Ophthalmol. , vol.20 , pp. 151-157
    • Javitt, N.B.1    Javitt, J.C.2
  • 85
    • 84867647498 scopus 로고    scopus 로고
    • Inflammation in aging: cause, effect, or both?
    • Jenny N.S. Inflammation in aging: cause, effect, or both?. Discovery Med. 2012, 13:451-460.
    • (2012) Discovery Med. , vol.13 , pp. 451-460
    • Jenny, N.S.1
  • 86
    • 33846259385 scopus 로고    scopus 로고
    • Autophagy of vascular smooth muscle cells in atherosclerotic lesions
    • Jia G., Cheng G., Agrawal D.K. Autophagy of vascular smooth muscle cells in atherosclerotic lesions. Autophagy 2007, 3:63-64.
    • (2007) Autophagy , vol.3 , pp. 63-64
    • Jia, G.1    Cheng, G.2    Agrawal, D.K.3
  • 94
    • 84898816567 scopus 로고    scopus 로고
    • Oxysterols and symptomatic versus asymptomatic human atherosclerotic plaque
    • Khatib S., Vaya J. Oxysterols and symptomatic versus asymptomatic human atherosclerotic plaque. Biochem. Biophys. Res. Commun. 2014, 446:709-713.
    • (2014) Biochem. Biophys. Res. Commun. , vol.446 , pp. 709-713
    • Khatib, S.1    Vaya, J.2
  • 95
    • 38449113816 scopus 로고    scopus 로고
    • 20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism
    • Kim W.K., Meliton V., Amantea C.M., Hahn T.J., Parhami F. 20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism. J. Bone Miner. Res. 2007, 22:1711-1719.
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 1711-1719
    • Kim, W.K.1    Meliton, V.2    Amantea, C.M.3    Hahn, T.J.4    Parhami, F.5
  • 96
    • 47749155975 scopus 로고    scopus 로고
    • Effects of amyloid β-peptides on the lysis tension of lipid bilayer vesicles containing oxysterols
    • Kim D.H., Frangos J.A. Effects of amyloid β-peptides on the lysis tension of lipid bilayer vesicles containing oxysterols. Biophys. J. 2008, 95:620-628.
    • (2008) Biophys. J. , vol.95 , pp. 620-628
    • Kim, D.H.1    Frangos, J.A.2
  • 97
    • 58849154028 scopus 로고    scopus 로고
    • Impact of 27-hydroxycholesterol on amyloid-beta peptide production and ATP-binding cassette transporter expression in primary human neurons
    • Kim W.S., Chan S.L., Hill A.F., Guillemin G.J., Garner B. Impact of 27-hydroxycholesterol on amyloid-beta peptide production and ATP-binding cassette transporter expression in primary human neurons. J. Alzheimers Dis. 2009, 16:121-131.
    • (2009) J. Alzheimers Dis. , vol.16 , pp. 121-131
    • Kim, W.S.1    Chan, S.L.2    Hill, A.F.3    Guillemin, G.J.4    Garner, B.5
  • 99
    • 65349164191 scopus 로고    scopus 로고
    • Serum 24S-hydroxycholesterol and hippocampal size in middle-aged normal individuals
    • Koschack J., Lütjohann D., Schmidt-Samoa C., Irle E. Serum 24S-hydroxycholesterol and hippocampal size in middle-aged normal individuals. Neurobiol. Aging 2009, 30:898-902.
    • (2009) Neurobiol. Aging , vol.30 , pp. 898-902
    • Koschack, J.1    Lütjohann, D.2    Schmidt-Samoa, C.3    Irle, E.4
  • 100
    • 84862851803 scopus 로고    scopus 로고
    • Interactions of amyloid â peptide Z. Kristofiková, 1-40 and cerebrosterol
    • Krištofiková Z., Kříž Z., Rípová D., Koča J. Interactions of amyloid â peptide Z. Kristofiková, 1-40 and cerebrosterol. Neurochem. Res. 2012, 37:604-613.
    • (2012) Neurochem. Res. , vol.37 , pp. 604-613
    • Krištofiková, Z.1    Kříž, Z.2    Rípová, D.3    Koča, J.4
  • 101
    • 77956801100 scopus 로고    scopus 로고
    • 7-Ketocholesterol-induced inflammation: involvement of multiple kinase signaling pathways via NF kappa B but independently of reactive oxygen species formation
    • Larrayoz I.M., Huang J.D., Lee J.W., Pascual I., Rodriguez I.R. 7-Ketocholesterol-induced inflammation: involvement of multiple kinase signaling pathways via NF kappa B but independently of reactive oxygen species formation. Invest. Ophthalmol. Visual Sci. 2010, 51:4942-4955.
    • (2010) Invest. Ophthalmol. Visual Sci. , vol.51 , pp. 4942-4955
    • Larrayoz, I.M.1    Huang, J.D.2    Lee, J.W.3    Pascual, I.4    Rodriguez, I.R.5
  • 102
    • 34547118363 scopus 로고    scopus 로고
    • In vivo interconversion of 7beta-hydroxycholesterol and 7-ketocholesterol, potential surrogate markers for oxidative stress
    • Larsson H., Böttiger Y., Iuliano L., Diczfalusy U. In vivo interconversion of 7beta-hydroxycholesterol and 7-ketocholesterol, potential surrogate markers for oxidative stress. Free Radical Biol. Med. 2007, 43:695-701.
    • (2007) Free Radical Biol. Med. , vol.43 , pp. 695-701
    • Larsson, H.1    Böttiger, Y.2    Iuliano, L.3    Diczfalusy, U.4
  • 103
    • 77957372866 scopus 로고    scopus 로고
    • APOE and cholesterol homeostasis in Alzheimer's disease
    • Leduc V., Jasmin-Bélanger S., Poirier J. APOE and cholesterol homeostasis in Alzheimer's disease. Trends Mol. Med. 2010, 16:469-477.
    • (2010) Trends Mol. Med. , vol.16 , pp. 469-477
    • Leduc, V.1    Jasmin-Bélanger, S.2    Poirier, J.3
  • 105
    • 0032421830 scopus 로고    scopus 로고
    • Different patterns of IL-1beta secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7alpha-, 7beta-hydroxycholesterol, or 7-ketocholesterol
    • Lemaire S., Lizard G., Monier S., Miguet C., Gueldry S., Volot F., Gambert P., Néel D. Different patterns of IL-1beta secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7alpha-, 7beta-hydroxycholesterol, or 7-ketocholesterol. FEBS Lett. 1998, 440:434-439.
    • (1998) FEBS Lett. , vol.440 , pp. 434-439
    • Lemaire, S.1    Lizard, G.2    Monier, S.3    Miguet, C.4    Gueldry, S.5    Volot, F.6    Gambert, P.7    Néel, D.8
  • 107
    • 65349111246 scopus 로고    scopus 로고
    • 7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent
    • Lemaire-Ewing S., Berthier A., Royer M.C., Logette E., Corcos L., Bouchot A., Monier S., Prunet C., Raveneau M., Rébé C., Desrumaux C., Lizard G., Néel D. 7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent. Cell Biol. Toxicol. 2009, 25:127-139.
    • (2009) Cell Biol. Toxicol. , vol.25 , pp. 127-139
    • Lemaire-Ewing, S.1    Berthier, A.2    Royer, M.C.3    Logette, E.4    Corcos, L.5    Bouchot, A.6    Monier, S.7    Prunet, C.8    Raveneau, M.9    Rébé, C.10    Desrumaux, C.11    Lizard, G.12    Néel, D.13
  • 110
    • 80051472136 scopus 로고    scopus 로고
    • Oxysterols as biomarkers in neurodegenerative diseases
    • Leoni V., Caccia C. Oxysterols as biomarkers in neurodegenerative diseases. Chem. Phys. Lipids 2011, 164:515-524.
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 515-524
    • Leoni, V.1    Caccia, C.2
  • 111
    • 79959196891 scopus 로고    scopus 로고
    • Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols
    • Li W., Ghosh M., Eftekhari S., Yuan X.M. Lipid accumulation and lysosomal pathways contribute to dysfunction and apoptosis of human endothelial cells caused by 7-oxysterols. Biochem. Biophys. Res. Commun. 2011, 409:711-716.
    • (2011) Biochem. Biophys. Res. Commun. , vol.409 , pp. 711-716
    • Li, W.1    Ghosh, M.2    Eftekhari, S.3    Yuan, X.M.4
  • 112
    • 0033802397 scopus 로고    scopus 로고
    • Digitalis and digitalis like compounds down-regulate gene expression of the intracellular signaling protein 14-3-3 in rat lens
    • Lichtstein D., McGowan M.H., Russell P., Carper D.A. Digitalis and digitalis like compounds down-regulate gene expression of the intracellular signaling protein 14-3-3 in rat lens. Hypertens. Res. 2000, 23:S51-S53.
    • (2000) Hypertens. Res. , vol.23 , pp. S51-S53
    • Lichtstein, D.1    McGowan, M.H.2    Russell, P.3    Carper, D.A.4
  • 113
    • 84874931751 scopus 로고    scopus 로고
    • Reactive oxygen species and the free radical theory of aging
    • Liochev S.I. Reactive oxygen species and the free radical theory of aging. Free Radical Biol. Med. 2013, 60:1-4.
    • (2013) Free Radical Biol. Med. , vol.60 , pp. 1-4
    • Liochev, S.I.1
  • 114
    • 8844228191 scopus 로고    scopus 로고
    • Cholestane-3beta, 5alpha, 6beta-triol promotes vascular smooth muscle cells calcification
    • Liu H., Yuan L., Xu S., Zhang T., Wang K. Cholestane-3beta, 5alpha, 6beta-triol promotes vascular smooth muscle cells calcification. Life Sci. 2004, 76:533-543.
    • (2004) Life Sci. , vol.76 , pp. 533-543
    • Liu, H.1    Yuan, L.2    Xu, S.3    Zhang, T.4    Wang, K.5
  • 115
    • 68149158208 scopus 로고    scopus 로고
    • Suppressor mechanisms in immune aging
    • Liu Y., Sharpless N.E. Suppressor mechanisms in immune aging. Curr. Opin. Immunol. 2009, 21:431-439.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 431-439
    • Liu, Y.1    Sharpless, N.E.2
  • 116
    • 26444540441 scopus 로고    scopus 로고
    • Cholestane-3beta, 5alpha, 6beta-triol inhibits osteoblastic differentiation and promotes apoptosis of rat bone marrow stromal cells
    • Liu H., Yuan L., Xu S., Wang K., Zhang T. Cholestane-3beta, 5alpha, 6beta-triol inhibits osteoblastic differentiation and promotes apoptosis of rat bone marrow stromal cells. J. Cell Biochem. 2005, 96:198-208.
    • (2005) J. Cell Biochem. , vol.96 , pp. 198-208
    • Liu, H.1    Yuan, L.2    Xu, S.3    Wang, K.4    Zhang, T.5
  • 119
    • 63249096864 scopus 로고    scopus 로고
    • Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases
    • Lordan S., Mackrill J.J., O'Brien N.M. Oxysterols and mechanisms of apoptotic signaling: implications in the pathology of degenerative diseases. J. Nutr. Biochem. 2009, 20:321-336.
    • (2009) J. Nutr. Biochem. , vol.20 , pp. 321-336
    • Lordan, S.1    Mackrill, J.J.2    O'Brien, N.M.3
  • 120
    • 52049099354 scopus 로고    scopus 로고
    • Role of oxidative stress and nitric oxide in atherothrombosis
    • Lubos E., Handy D.E., Loscalzo J. Role of oxidative stress and nitric oxide in atherothrombosis. Front Biosci. 2008, 13:5323-5344.
    • (2008) Front Biosci. , vol.13 , pp. 5323-5344
    • Lubos, E.1    Handy, D.E.2    Loscalzo, J.3
  • 121
    • 0032545281 scopus 로고    scopus 로고
    • CDNA cloning of mouse and human cholesterol 25-hydroxylases, polytoptic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism
    • Lund E., Kerr T.A., Sakai J., Li W.P., Russell D.W. cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytoptic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism. J. Biol. Chem. 1998, 273:34316-34327.
    • (1998) J. Biol. Chem. , vol.273 , pp. 34316-34327
    • Lund, E.1    Kerr, T.A.2    Sakai, J.3    Li, W.P.4    Russell, D.W.5
  • 122
    • 0033594903 scopus 로고    scopus 로고
    • CDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain
    • Lund E.G., Guileyardo J.M., Russell D.W. cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:7238-7243.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 7238-7243
    • Lund, E.G.1    Guileyardo, J.M.2    Russell, D.W.3
  • 125
    • 0029446145 scopus 로고
    • From cholesterol to oxysterols current data
    • Luu B. From cholesterol to oxysterols current data. C.R. Seances Soc. Biol. Fil. 1995, 189:827-837.
    • (1995) C.R. Seances Soc. Biol. Fil. , vol.189 , pp. 827-837
    • Luu, B.1
  • 126
    • 51949086031 scopus 로고    scopus 로고
    • Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol
    • Malvitte L., Montange T., Vejux A., Joffre C., Bron A., Creuzot-Garcher C., Lizard G. Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol. Curr. Eye Res. 2008, 33:769-781.
    • (2008) Curr. Eye Res. , vol.33 , pp. 769-781
    • Malvitte, L.1    Montange, T.2    Vejux, A.3    Joffre, C.4    Bron, A.5    Creuzot-Garcher, C.6    Lizard, G.7
  • 129
    • 77953269718 scopus 로고    scopus 로고
    • Brain cholesterol in normal and pathological aging
    • Martin M., Dotti C.G., Ledesma M.D. Brain cholesterol in normal and pathological aging. Biochim. Biophys. Acta 2010, 1801:934-944.
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 934-944
    • Martin, M.1    Dotti, C.G.2    Ledesma, M.D.3
  • 131
    • 47749117627 scopus 로고    scopus 로고
    • Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain
    • Mast N., White M.A., Bjorkhem I., Johnson E.F., Stout C.D., Pikuleva I.A. Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:9546-9551.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 9546-9551
    • Mast, N.1    White, M.A.2    Bjorkhem, I.3    Johnson, E.F.4    Stout, C.D.5    Pikuleva, I.A.6
  • 132
    • 0030902933 scopus 로고    scopus 로고
    • Increased oxysterol contents in diabetic rat hearts: their involvement in diabetic cardiomyopathy
    • Matsui H., Okumura K., Mukawa H., Hibino M., Toki Y., Ito T. Increased oxysterol contents in diabetic rat hearts: their involvement in diabetic cardiomyopathy. Can. J. Cardiol. 1997, 13:373-379.
    • (1997) Can. J. Cardiol. , vol.13 , pp. 373-379
    • Matsui, H.1    Okumura, K.2    Mukawa, H.3    Hibino, M.4    Toki, Y.5    Ito, T.6
  • 133
    • 84872498729 scopus 로고    scopus 로고
    • Role of cholesterol in APP metabolism and its significance in Alzheimer's disease pathogenesis
    • Maulik M., Westaway D., Jhamandas J.H., Kar S. Role of cholesterol in APP metabolism and its significance in Alzheimer's disease pathogenesis. Mol. Neurobiol. 2013, 47:37-63.
    • (2013) Mol. Neurobiol. , vol.47 , pp. 37-63
    • Maulik, M.1    Westaway, D.2    Jhamandas, J.H.3    Kar, S.4
  • 134
    • 0032990716 scopus 로고    scopus 로고
    • +-ATPase inhibitors down-regulate gene expression of the intracellular signaling protein 14-3-3 in rat lens
    • +-ATPase inhibitors down-regulate gene expression of the intracellular signaling protein 14-3-3 in rat lens. J. Pharmacol. Exp. Ther. 1999, 289:1559-1563.
    • (1999) J. Pharmacol. Exp. Ther. , vol.289 , pp. 1559-1563
    • McGowan, M.H.1    Russell, P.2    Carper, D.A.3    Lichtstein, D.4
  • 135
    • 79952969257 scopus 로고    scopus 로고
    • Correlation between serum content of the main COPs (cholesterol oxidation products) from autoxidation and cardiovascular risk factors
    • Menéndez-Carreño M., Varo N., Mugueta C., Restituto P., Ansorena D., Astiasarán I. Correlation between serum content of the main COPs (cholesterol oxidation products) from autoxidation and cardiovascular risk factors. Nutr. Hosp. 2011, 26:144-151.
    • (2011) Nutr. Hosp. , vol.26 , pp. 144-151
    • Menéndez-Carreño, M.1    Varo, N.2    Mugueta, C.3    Restituto, P.4    Ansorena, D.5    Astiasarán, I.6
  • 136
    • 0034746291 scopus 로고    scopus 로고
    • Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death
    • Miguet C., Monier S., Bettaieb A., Athias A., Besséde G., Laubriet A., Lemaire S., Néel D., Gambert P., Lizard G. Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. Cell Death Differ. 2001, 8:83-99.
    • (2001) Cell Death Differ. , vol.8 , pp. 83-99
    • Miguet, C.1    Monier, S.2    Bettaieb, A.3    Athias, A.4    Besséde, G.5    Laubriet, A.6    Lemaire, S.7    Néel, D.8    Gambert, P.9    Lizard, G.10
  • 137
    • 84895817637 scopus 로고    scopus 로고
    • Sirtuins in neurodegenerative diseases: an update on potential mechanisms
    • Min S.W., Sohn P.D., Cho S.H., Swanson R.A., Gan L. Sirtuins in neurodegenerative diseases: an update on potential mechanisms. Front. Aging Neurosci. 2013, 25(5):53.
    • (2013) Front. Aging Neurosci. , vol.25 , Issue.5 , pp. 53
    • Min, S.W.1    Sohn, P.D.2    Cho, S.H.3    Swanson, R.A.4    Gan, L.5
  • 138
    • 77954217091 scopus 로고    scopus 로고
    • Interaction of two oxysterols, 7-ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes
    • Mintzer E., Charles G., Gordon S. Interaction of two oxysterols, 7-ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes. Chem. Phys. Lipids 2010, 163:586-593.
    • (2010) Chem. Phys. Lipids , vol.163 , pp. 586-593
    • Mintzer, E.1    Charles, G.2    Gordon, S.3
  • 143
    • 84871489412 scopus 로고    scopus 로고
    • The molecular mechanisms underlying the pharmacological actions of estrogens SERMs and oxysterols: implications for the treatment and prevention of osteoporosis
    • Nelson E.R., Wardell S.E., McDonnell D.P. The molecular mechanisms underlying the pharmacological actions of estrogens SERMs and oxysterols: implications for the treatment and prevention of osteoporosis. Bone 2013, 53:42-50.
    • (2013) Bone , vol.53 , pp. 42-50
    • Nelson, E.R.1    Wardell, S.E.2    McDonnell, D.P.3
  • 144
    • 84887043169 scopus 로고    scopus 로고
    • Improved synthesis and in vitro evaluation of the cytotoxic profile of oxysterols oxidized at C4 (4α- and 4β-hydroxycholesterol) and C7 (7-ketocholesterol, 7α- and 7β-hydroxycholesterol) on cells of the central nervous system
    • Nury T., Samadi M., Zarrouk A., Riedinger J.M., Lizard G. Improved synthesis and in vitro evaluation of the cytotoxic profile of oxysterols oxidized at C4 (4α- and 4β-hydroxycholesterol) and C7 (7-ketocholesterol, 7α- and 7β-hydroxycholesterol) on cells of the central nervous system. Eur. J. Med. Chem. 2013, 70:558-567.
    • (2013) Eur. J. Med. Chem. , vol.70 , pp. 558-567
    • Nury, T.1    Samadi, M.2    Zarrouk, A.3    Riedinger, J.M.4    Lizard, G.5
  • 145
    • 84898825859 scopus 로고    scopus 로고
    • Induction of oxiapoptophagy, a mixed mode of cell death associated with oxidative stress, apoptosis and autophagy, on 7-ketocholesterol-treated 158N murine oligodendrocytes: impairment by α-tocopherol
    • Nury T., Zarrouk A., Vejux A., Doria M., Riedinger J.M., Delage-Mourroux R., Lizard G. Induction of oxiapoptophagy, a mixed mode of cell death associated with oxidative stress, apoptosis and autophagy, on 7-ketocholesterol-treated 158N murine oligodendrocytes: impairment by α-tocopherol. Biochem. Biophys. Res. Commun. 2014, 446:714-719.
    • (2014) Biochem. Biophys. Res. Commun. , vol.446 , pp. 714-719
    • Nury, T.1    Zarrouk, A.2    Vejux, A.3    Doria, M.4    Riedinger, J.M.5    Delage-Mourroux, R.6    Lizard, G.7
  • 146
    • 85028217080 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase 1: regeneration of active glucocorticoids is only part of the story
    • (pii: S0960-0760(14)00190-3)
    • Odermatt A., Klusonova P. 11β-Hydroxysteroid dehydrogenase 1: regeneration of active glucocorticoids is only part of the story. J. Steroid Biochem. Mol. Biol. 2014, (pii: S0960-0760(14)00190-3). 10.1016/j.jsbmb.2014.08.011.
    • (2014) J. Steroid Biochem. Mol. Biol.
    • Odermatt, A.1    Klusonova, P.2
  • 147
    • 84890826882 scopus 로고    scopus 로고
    • Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death
    • Okabe A., Urano Y., Itoh S., Suda N., Kotani R., Nishimura Y., Saito Y., Noguchi N. Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death. Redox Biol. 2013, 2:28-35.
    • (2013) Redox Biol. , vol.2 , pp. 28-35
    • Okabe, A.1    Urano, Y.2    Itoh, S.3    Suda, N.4    Kotani, R.5    Nishimura, Y.6    Saito, Y.7    Noguchi, N.8
  • 148
    • 84884293024 scopus 로고    scopus 로고
    • Oxysterol-binding proteins: sterol and phosphoinositide sensors coordinating transport, signaling and metabolism
    • Olkkonen V.M., Li S. Oxysterol-binding proteins: sterol and phosphoinositide sensors coordinating transport, signaling and metabolism. Prog. Lipid Res. 2013, 52:529-538.
    • (2013) Prog. Lipid Res. , vol.52 , pp. 529-538
    • Olkkonen, V.M.1    Li, S.2
  • 153
    • 77952960864 scopus 로고    scopus 로고
    • GSK-3beta: a central kinase for neurodegenerative diseases?
    • Petit-Paitel A. GSK-3beta: a central kinase for neurodegenerative diseases?. Med. Sci. (Paris) 2010, 26:516-521.
    • (2010) Med. Sci. (Paris) , vol.26 , pp. 516-521
    • Petit-Paitel, A.1
  • 155
    • 33645106219 scopus 로고    scopus 로고
    • Cholesterol-metabolizing cytochromes P450
    • Pikuleva I.A. Cholesterol-metabolizing cytochromes P450. Drug Metab. Dispos. 2006, 34:513-520.
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 513-520
    • Pikuleva, I.A.1
  • 156
    • 84925545770 scopus 로고    scopus 로고
    • Cholesterol in the retina: the best is yet to come
    • Pikuleva I.A., Curcio C.A. Cholesterol in the retina: the best is yet to come. Prog. Retin. Eye Res 2014, 41C:64-89.
    • (2014) Prog. Retin. Eye Res , vol.41 C , pp. 64-89
    • Pikuleva, I.A.1    Curcio, C.A.2
  • 157
    • 84878798159 scopus 로고    scopus 로고
    • Oxysterols in the pathogenesis of major chronic diseases
    • Poli G., Biasi F., Leonarduzzi G. Oxysterols in the pathogenesis of major chronic diseases. Redox Biol. 2013, 1:125-130.
    • (2013) Redox Biol. , vol.1 , pp. 125-130
    • Poli, G.1    Biasi, F.2    Leonarduzzi, G.3
  • 159
    • 62149140601 scopus 로고    scopus 로고
    • Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells
    • Prasanthi J.R., Huls A., Thomasson S., Thompson A., Schommer E., Ghribi O. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells. Mol. Neurodegener. 2009, 4:1.
    • (2009) Mol. Neurodegener. , vol.4 , pp. 1
    • Prasanthi, J.R.1    Huls, A.2    Thomasson, S.3    Thompson, A.4    Schommer, E.5    Ghribi, O.6
  • 161
    • 29544448727 scopus 로고    scopus 로고
    • High circulating levels of 7beta- and 7alpha-hydroxycholesterol and presence of apoptotic and oxidative markers in arterial lesions of normocholesterolemic atherosclerotic patients undergoing endarterectomy
    • Prunet C., Petit J.M., Ecarnot-Laubriet A., Athias A., Miguet-Alfonsi C., Rohmer J.F., Steinmetz E., Néel D., Gambert P., Lizard G. High circulating levels of 7beta- and 7alpha-hydroxycholesterol and presence of apoptotic and oxidative markers in arterial lesions of normocholesterolemic atherosclerotic patients undergoing endarterectomy. Pathol. Biol. (Paris) 2006, 54:22-32.
    • (2006) Pathol. Biol. (Paris) , vol.54 , pp. 22-32
    • Prunet, C.1    Petit, J.M.2    Ecarnot-Laubriet, A.3    Athias, A.4    Miguet-Alfonsi, C.5    Rohmer, J.F.6    Steinmetz, E.7    Néel, D.8    Gambert, P.9    Lizard, G.10
  • 162
    • 11844287647 scopus 로고    scopus 로고
    • Ozone exposure in vivo and formation of biologically active oxysterols in the lung
    • Pulfer M.K., Taube C., Gelfand E., Murphy R.C. Ozone exposure in vivo and formation of biologically active oxysterols in the lung. J. Pharmacol. Exp. Ther. 2005, 312:256-264.
    • (2005) J. Pharmacol. Exp. Ther. , vol.312 , pp. 256-264
    • Pulfer, M.K.1    Taube, C.2    Gelfand, E.3    Murphy, R.C.4
  • 163
    • 80051472674 scopus 로고    scopus 로고
    • α-Tocopherol impairs 7-ketocholesterol-induced caspase-3-dependent apoptosis involving GSK-3 activation and Mcl-1 degradation on 158N murine oligodendrocytes
    • Ragot K., Delmas D., Athias A., Nury T., Baarine M., Lizard G. α-Tocopherol impairs 7-ketocholesterol-induced caspase-3-dependent apoptosis involving GSK-3 activation and Mcl-1 degradation on 158N murine oligodendrocytes. Chem. Phys. Lipids 2011, 164:469-478.
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 469-478
    • Ragot, K.1    Delmas, D.2    Athias, A.3    Nury, T.4    Baarine, M.5    Lizard, G.6
  • 165
    • 0017368476 scopus 로고    scopus 로고
    • Fecal bile acids and cholesterol metabolites of patients with ulcerative colitis, a high-risk group for development of colon cancer
    • Reddy B.S., Martin C.W., Wynder E.L. Fecal bile acids and cholesterol metabolites of patients with ulcerative colitis, a high-risk group for development of colon cancer. Cancer Res. 1997, 37:1697-1701.
    • (1997) Cancer Res. , vol.37 , pp. 1697-1701
    • Reddy, B.S.1    Martin, C.W.2    Wynder, E.L.3
  • 166
    • 0018749426 scopus 로고
    • Effect of cholesterol metabolites and promoting effect of lithocholic acid in colon carcinogenesis in germ-free and conventional F344 rats
    • Reddy B.S., Watanabe K. Effect of cholesterol metabolites and promoting effect of lithocholic acid in colon carcinogenesis in germ-free and conventional F344 rats. Cancer Res. 1979, 39:1521-1524.
    • (1979) Cancer Res. , vol.39 , pp. 1521-1524
    • Reddy, B.S.1    Watanabe, K.2
  • 168
    • 33947573706 scopus 로고    scopus 로고
    • Oxysterol-induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC- and PKA-dependent pathway
    • Richardson J.A., Amantea C.M., Kianmahd B., Tetradis S., Lieberman J.R., Hahn T.J., Parhami F. Oxysterol-induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC- and PKA-dependent pathway. J. Biol. Chem. 2007, 100:1131-1145.
    • (2007) J. Biol. Chem. , vol.100 , pp. 1131-1145
    • Richardson, J.A.1    Amantea, C.M.2    Kianmahd, B.3    Tetradis, S.4    Lieberman, J.R.5    Hahn, T.J.6    Parhami, F.7
  • 169
    • 0026732689 scopus 로고
    • The prevention and treatment of osteoporosis
    • Riggs B.L., Melton L.J. The prevention and treatment of osteoporosis. New Engl. J. Med. 1992, 327:620-627.
    • (1992) New Engl. J. Med. , vol.327 , pp. 620-627
    • Riggs, B.L.1    Melton, L.J.2
  • 170
    • 84867799739 scopus 로고    scopus 로고
    • The Hedgehog signal transduction network
    • Robbins D.J., Fei D.L., Riobo N.A. The Hedgehog signal transduction network. Sci. Signal. 2012, 5(246):re6.
    • (2012) Sci. Signal. , vol.5 , Issue.246 , pp. re6
    • Robbins, D.J.1    Fei, D.L.2    Riobo, N.A.3
  • 172
    • 44349141839 scopus 로고    scopus 로고
    • Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1
    • Romeo G.R., Kazlauskas A. Oxysterol and diabetes activate STAT3 and control endothelial expression of profilin-1 via OSBP1. J. Biol. Chem. 2008, 283:9595-9605.
    • (2008) J. Biol. Chem. , vol.283 , pp. 9595-9605
    • Romeo, G.R.1    Kazlauskas, A.2
  • 173
    • 67650179212 scopus 로고    scopus 로고
    • 7-ketocholesterol incorporation into sphingolipid/cholesterol-enriched (lipid raft) domains is impaired by vitamin E: a specific role for alpha-tocopherol with consequences on cell death
    • Royer M.C., Lemaire-Ewing S., Desrumaux C., Monier S., Pais de Barros J.P., Athias A., Néel D., Lagrost L. 7-ketocholesterol incorporation into sphingolipid/cholesterol-enriched (lipid raft) domains is impaired by vitamin E: a specific role for alpha-tocopherol with consequences on cell death. J. Biol. Chem. 2009, 284:15826-15834.
    • (2009) J. Biol. Chem. , vol.284 , pp. 15826-15834
    • Royer, M.C.1    Lemaire-Ewing, S.2    Desrumaux, C.3    Monier, S.4    Pais de Barros, J.P.5    Athias, A.6    Néel, D.7    Lagrost, L.8
  • 174
    • 77952741778 scopus 로고    scopus 로고
    • Plant sterols and stanols for healthy ageing
    • Rudkowska I. Plant sterols and stanols for healthy ageing. Maturitas 2010, 66:158-162.
    • (2010) Maturitas , vol.66 , pp. 158-162
    • Rudkowska, I.1
  • 175
    • 69249213701 scopus 로고    scopus 로고
    • Esterified cholesterol is highly localized to Bruch's membrane, as revealed by lipid histochemistry in wholemounts of human choroid
    • Rudolf M., Curcio C.A. Esterified cholesterol is highly localized to Bruch's membrane, as revealed by lipid histochemistry in wholemounts of human choroid. J. Histochem. Cytochem. 2009, 57:731-739.
    • (2009) J. Histochem. Cytochem. , vol.57 , pp. 731-739
    • Rudolf, M.1    Curcio, C.A.2
  • 176
    • 84884331435 scopus 로고    scopus 로고
    • Interrelationship between ATP-binding cassette transporters and oxysterols
    • Ruiz J.L., Fernandes L.R., Levy D., Bydlowski S.P. Interrelationship between ATP-binding cassette transporters and oxysterols. Biochem. Pharmacol. 2013, 86:80-88.
    • (2013) Biochem. Pharmacol. , vol.86 , pp. 80-88
    • Ruiz, J.L.1    Fernandes, L.R.2    Levy, D.3    Bydlowski, S.P.4
  • 177
    • 0037378889 scopus 로고    scopus 로고
    • Isolation and lipid characterization of cholesterol-enriched fractions in cortical and nuclear human lens fibers
    • Rujoi M., Jin J., Borchman D., Tang D., Yappert M.C. Isolation and lipid characterization of cholesterol-enriched fractions in cortical and nuclear human lens fibers. Invest. Ophthalmol. Visual Sci. 2003, 44:1634-1642.
    • (2003) Invest. Ophthalmol. Visual Sci. , vol.44 , pp. 1634-1642
    • Rujoi, M.1    Jin, J.2    Borchman, D.3    Tang, D.4    Yappert, M.C.5
  • 178
    • 0034672672 scopus 로고    scopus 로고
    • Oxysterol biosynthetic enzymes
    • Russell D.W. Oxysterol biosynthetic enzymes. Biochim. Biophys. Acta 2000, 1529:126-135.
    • (2000) Biochim. Biophys. Acta , vol.1529 , pp. 126-135
    • Russell, D.W.1
  • 179
  • 180
    • 84982064807 scopus 로고
    • Photosensitized autoxidation of steroids preparation of steroid hydroperoxides by means of phototoxic photosentitizers
    • Schenck G.O., Gollnick K., Neümuller O.A. Photosensitized autoxidation of steroids preparation of steroid hydroperoxides by means of phototoxic photosentitizers. Liebigs Ann. 1957, 603:46.
    • (1957) Liebigs Ann. , vol.603 , pp. 46
    • Schenck, G.O.1    Gollnick, K.2    Neümuller, O.A.3
  • 181
    • 48249108656 scopus 로고    scopus 로고
    • Lipid homeostasis in macrophages-implications for atherosclerosis
    • Schmitz G., Grandl M. Lipid homeostasis in macrophages-implications for atherosclerosis. Rev. Physiol. Biochem. Pharmacol. 2008, 160:93-125.
    • (2008) Rev. Physiol. Biochem. Pharmacol. , vol.160 , pp. 93-125
    • Schmitz, G.1    Grandl, M.2
  • 182
    • 67349096844 scopus 로고    scopus 로고
    • Endolysosomal phospholipidosis and cytosolic lipid droplet storage and release in macrophages
    • Schmitz G., Grandl M. Endolysosomal phospholipidosis and cytosolic lipid droplet storage and release in macrophages. Biochim. Biophys. Acta 2009, 1791:524-539.
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 524-539
    • Schmitz, G.1    Grandl, M.2
  • 183
    • 0025941838 scopus 로고
    • Structure and function of lamellar bodies, lipid-protein complexes involved in storage and secretion of cellular lipids
    • Schmitz G., Müller G. Structure and function of lamellar bodies, lipid-protein complexes involved in storage and secretion of cellular lipids. J. Lipid Res. 1991, 32:1539-1570.
    • (1991) J. Lipid Res. , vol.32 , pp. 1539-1570
    • Schmitz, G.1    Müller, G.2
  • 184
    • 84884218102 scopus 로고    scopus 로고
    • Dietary cholesterol increases ventricular volume and narrows cerebrovascular diameter in a rabbit model of Alzheimer's disease
    • Schreurs B.G., Smith-Bell C.A., Lemieux S.K. Dietary cholesterol increases ventricular volume and narrows cerebrovascular diameter in a rabbit model of Alzheimer's disease. Neuroscience 2013, 254:61-69.
    • (2013) Neuroscience , vol.254 , pp. 61-69
    • Schreurs, B.G.1    Smith-Bell, C.A.2    Lemieux, S.K.3
  • 185
    • 0342316532 scopus 로고    scopus 로고
    • Oxysterols: modulators of cholesterol metabolism and other processes
    • Schroepfer G.J. Oxysterols: modulators of cholesterol metabolism and other processes. Physiol. Rev. 2000, 80:361-554.
    • (2000) Physiol. Rev. , vol.80 , pp. 361-554
    • Schroepfer, G.J.1
  • 186
    • 2442513350 scopus 로고    scopus 로고
    • Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme
    • Schweizer R.A., Zürcher M., Balazs Z., Dick B., Odermatt A. Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme. J. Biol. Chem. 2004, 279:18415-18424.
    • (2004) J. Biol. Chem. , vol.279 , pp. 18415-18424
    • Schweizer, R.A.1    Zürcher, M.2    Balazs, Z.3    Dick, B.4    Odermatt, A.5
  • 187
    • 84904614112 scopus 로고    scopus 로고
    • Why AMD is a disease of ageing and not of development: mechanisms and insights
    • Sharma K., Sharma N.K., Anand A. Why AMD is a disease of ageing and not of development: mechanisms and insights. Front. Aging Neurosci. 2014, 6:151.
    • (2014) Front. Aging Neurosci. , vol.6 , pp. 151
    • Sharma, K.1    Sharma, N.K.2    Anand, A.3
  • 188
    • 77958057683 scopus 로고    scopus 로고
    • Macrophages, oxysterols and atherosclerosis
    • Shibata N., Glass C.K. Macrophages, oxysterols and atherosclerosis. Circ. J. 2010, 74:2045-2051.
    • (2010) Circ. J. , vol.74 , pp. 2045-2051
    • Shibata, N.1    Glass, C.K.2
  • 189
    • 0038153121 scopus 로고    scopus 로고
    • Osteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cells
    • Silva J., Beckedorf A., Bieberich E. Osteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cells. J. Biol. Chem. 2003, 278:25376-25385.
    • (2003) J. Biol. Chem. , vol.278 , pp. 25376-25385
    • Silva, J.1    Beckedorf, A.2    Bieberich, E.3
  • 190
    • 84896943168 scopus 로고    scopus 로고
    • Cancer. Cholesterol and cancer, in the balance
    • Silvente-Poirot S., Poirot M. Cancer. Cholesterol and cancer, in the balance. Science 2014, 343:1445-1446.
    • (2014) Science , vol.343 , pp. 1445-1446
    • Silvente-Poirot, S.1    Poirot, M.2
  • 192
    • 77249130073 scopus 로고    scopus 로고
    • Controlling the angiogenic switch in developing atherosclerotic plaques: possible targets for therapeutic intervention
    • Slevin M., Krupinski J., Badimon L. Controlling the angiogenic switch in developing atherosclerotic plaques: possible targets for therapeutic intervention. J. Angiogenes Res. 2009, 1:4.
    • (2009) J. Angiogenes Res. , vol.1 , pp. 4
    • Slevin, M.1    Krupinski, J.2    Badimon, L.3
  • 194
    • 0023243055 scopus 로고
    • Cholesterol autoxidation 1981-1986
    • Smith L.L. Cholesterol autoxidation 1981-1986. Chem. Phys. Lipids 1987, 44:87-125.
    • (1987) Chem. Phys. Lipids , vol.44 , pp. 87-125
    • Smith, L.L.1
  • 196
    • 0025057160 scopus 로고
    • Lipid compositions of different regions of the human brain during aging
    • Söderberg M., Edlund C., Kristensson K., Dallner G. Lipid compositions of different regions of the human brain during aging. J. Neurochem. 1990, 54:415-423.
    • (1990) J. Neurochem. , vol.54 , pp. 415-423
    • Söderberg, M.1    Edlund, C.2    Kristensson, K.3    Dallner, G.4
  • 198
    • 84883181808 scopus 로고    scopus 로고
    • Sterols and oxysterols in immune cell function
    • Spann N.J., Glass C.K. Sterols and oxysterols in immune cell function. Nat. Immunol. 2013, 14:893-900.
    • (2013) Nat. Immunol. , vol.14 , pp. 893-900
    • Spann, N.J.1    Glass, C.K.2
  • 199
    • 0028177562 scopus 로고
    • Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
    • Sparks D.L., Scheff S.W., Hunsaker J.C., Liu H., Landers T., Gross D.R. Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol. Exp. Neurol. 1994, 126:88-94.
    • (1994) Exp. Neurol. , vol.126 , pp. 88-94
    • Sparks, D.L.1    Scheff, S.W.2    Hunsaker, J.C.3    Liu, H.4    Landers, T.5    Gross, D.R.6
  • 200
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • Stocker R., Keaney J.F. Role of oxidative modifications in atherosclerosis. Physiology 2004, 84:1381-1478.
    • (2004) Physiology , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney, J.F.2
  • 201
    • 0028099263 scopus 로고
    • Membrane lipids of adult human brain: lipid composition of frontal and temporal lobe in subjects of age 20 to 100 years
    • Svennerholm L., Boström K., Jungbjer B., Olsson L. Membrane lipids of adult human brain: lipid composition of frontal and temporal lobe in subjects of age 20 to 100 years. J. Neurochem. 1994, 63:1802-1811.
    • (1994) J. Neurochem. , vol.63 , pp. 1802-1811
    • Svennerholm, L.1    Boström, K.2    Jungbjer, B.3    Olsson, L.4
  • 204
    • 45249117903 scopus 로고    scopus 로고
    • High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice
    • Thirumangalakudi L., Prakasam A., Zhang R., Bimonte-Nelson H., Sambamurti K., Kindy M.S., Bhat N.R. High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice. J. Neurochem. 2008, 106:475-485.
    • (2008) J. Neurochem. , vol.106 , pp. 475-485
    • Thirumangalakudi, L.1    Prakasam, A.2    Zhang, R.3    Bimonte-Nelson, H.4    Sambamurti, K.5    Kindy, M.S.6    Bhat, N.R.7
  • 205
    • 79751472085 scopus 로고    scopus 로고
    • Peroxisome metabolism and cellular aging
    • Titorenko V.I., Terlecky S.R. Peroxisome metabolism and cellular aging. Traffic 2011, 12:252-259.
    • (2011) Traffic , vol.12 , pp. 252-259
    • Titorenko, V.I.1    Terlecky, S.R.2
  • 206
    • 38449105997 scopus 로고    scopus 로고
    • The aging process and potential interventions to extend life expectancy
    • Tosato M., Zamboni V., Ferrini A., Cesari M. The aging process and potential interventions to extend life expectancy. Clin. Interventions Aging 2007, 2:401-412.
    • (2007) Clin. Interventions Aging , vol.2 , pp. 401-412
    • Tosato, M.1    Zamboni, V.2    Ferrini, A.3    Cesari, M.4
  • 209
    • 34548231638 scopus 로고    scopus 로고
    • Oxysterols, cholesterol homeostasis, and Alzheimer disease
    • Vaya J., Schipper H.M. Oxysterols, cholesterol homeostasis, and Alzheimer disease. J. Neurochem. 2007, 102:1727-1737.
    • (2007) J. Neurochem. , vol.102 , pp. 1727-1737
    • Vaya, J.1    Schipper, H.M.2
  • 210
    • 80051472916 scopus 로고    scopus 로고
    • Oxysterols formation as a reflection of biochemical pathways: summary of in vitro and in vivo studies
    • Vaya J., Szuchman A., Tavori H., Aluf Y. Oxysterols formation as a reflection of biochemical pathways: summary of in vitro and in vivo studies. Chem. Phys. Lipids 2011, 164:438-442.
    • (2011) Chem. Phys. Lipids , vol.164 , pp. 438-442
    • Vaya, J.1    Szuchman, A.2    Tavori, H.3    Aluf, Y.4
  • 211
    • 20144388767 scopus 로고    scopus 로고
    • 7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry FRET biphoton spectral imaging microscopy, and subcellular fractionation
    • Vejux A., Kahn E., Dumas D., Bessède G., Ménétrier F., Athias A., Riedinger J.M., Frouin F., Stoltz J.F., Ogier-Denis E., Todd-Pokropek A., Lizard G. 7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry FRET biphoton spectral imaging microscopy, and subcellular fractionation. Cytometry A 2005, 64:87-100.
    • (2005) Cytometry A , vol.64 , pp. 87-100
    • Vejux, A.1    Kahn, E.2    Dumas, D.3    Bessède, G.4    Ménétrier, F.5    Athias, A.6    Riedinger, J.M.7    Frouin, F.8    Stoltz, J.F.9    Ogier-Denis, E.10    Todd-Pokropek, A.11    Lizard, G.12
  • 212
    • 57049189735 scopus 로고    scopus 로고
    • Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis
    • Vejux A., Guyot S., Montange T., Riedinger J.M., Kahn E., Lizard G. Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis. J. Nutr. Biochem. 2009, 20:45-61.
    • (2009) J. Nutr. Biochem. , vol.20 , pp. 45-61
    • Vejux, A.1    Guyot, S.2    Montange, T.3    Riedinger, J.M.4    Kahn, E.5    Lizard, G.6
  • 213
    • 67349159434 scopus 로고    scopus 로고
    • Cytotoxic effects of oxysterols associated with human diseases: induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis
    • Vejux A., Lizard G. Cytotoxic effects of oxysterols associated with human diseases: induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis. Mol. Aspects Med. 2009, 30:153-170.
    • (2009) Mol. Aspects Med. , vol.30 , pp. 153-170
    • Vejux, A.1    Lizard, G.2
  • 214
    • 84860317712 scopus 로고    scopus 로고
    • Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments
    • Vejux A., Samadi M., Lizard G. Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments. J. Ophthalmol. 2011, 2011:471947.
    • (2011) J. Ophthalmol. , vol.2011 , pp. 471947
    • Vejux, A.1    Samadi, M.2    Lizard, G.3
  • 215
    • 69449104587 scopus 로고    scopus 로고
    • Early cortical lens opacities: a short overview
    • Vrensen G.F. Early cortical lens opacities: a short overview. Acta Ophtalmol 2009, 87:602-610.
    • (2009) Acta Ophtalmol , vol.87 , pp. 602-610
    • Vrensen, G.F.1
  • 217
    • 84908258389 scopus 로고    scopus 로고
    • Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation
    • (pii: S0891-5849(14)00343-8)
    • Vurusaner B., Gamba P., Testa G., Gargiulo S., Biasi F., Zerbinati C., Iuliano L., Leonarduzzi G., Basaga H., Poli G. Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation. Free Radical Biol. Med. 2014, (pii: S0891-5849(14)00343-8). 10.1016/j.freeradbiomed.2014.07.026.
    • (2014) Free Radical Biol. Med.
    • Vurusaner, B.1    Gamba, P.2    Testa, G.3    Gargiulo, S.4    Biasi, F.5    Zerbinati, C.6    Iuliano, L.7    Leonarduzzi, G.8    Basaga, H.9    Poli, G.10
  • 218
    • 0942290630 scopus 로고    scopus 로고
    • Relationship between sterol/steroid structure and participation in ordered lipid domains (lipid rafts): implications for lipid raft structure and function
    • Wang J., Megha London E. Relationship between sterol/steroid structure and participation in ordered lipid domains (lipid rafts): implications for lipid raft structure and function. Biochemistry 2004, 43:1010-1018.
    • (2004) Biochemistry , vol.43 , pp. 1010-1018
    • Wang, J.1    Megha London, E.2
  • 221
    • 84899490048 scopus 로고    scopus 로고
    • Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis
    • Wood W.G., Li L., Müller W.E., Eckert G.P. Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis. J. Neurochem. 2014, 129:559-572.
    • (2014) J. Neurochem. , vol.129 , pp. 559-572
    • Wood, W.G.1    Li, L.2    Müller, W.E.3    Eckert, G.P.4
  • 222
    • 34447628317 scopus 로고    scopus 로고
    • A rabbit model of Alzheimer's disease: valid at neuropathological, cognitive, and therapeutic levels
    • Woodruff-Pak D.S., Agelan A., Del Valle L. A rabbit model of Alzheimer's disease: valid at neuropathological, cognitive, and therapeutic levels. J. Alzheimers Dis. 2007, 11:371-383.
    • (2007) J. Alzheimers Dis. , vol.11 , pp. 371-383
    • Woodruff-Pak, D.S.1    Agelan, A.2    Del Valle, L.3
  • 223
    • 1542724860 scopus 로고    scopus 로고
    • Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis
    • Yoon J.H., Canbay A.E., Werneburg N.W., Lee S.P., Gores G.J. Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis. Hepatology 2004, 39:732-738.
    • (2004) Hepatology , vol.39 , pp. 732-738
    • Yoon, J.H.1    Canbay, A.E.2    Werneburg, N.W.3    Lee, S.P.4    Gores, G.J.5
  • 224
    • 0033950037 scopus 로고    scopus 로고
    • Lysosomal destabilization during macrophage damage induced by cholesterol oxidation products
    • Yuan X.M., Li W., Brunk U.T., Dalen H., Chang Y.H., Sevanian A. Lysosomal destabilization during macrophage damage induced by cholesterol oxidation products. Free Radical Biol. Med. 2000, 28:208-218.
    • (2000) Free Radical Biol. Med. , vol.28 , pp. 208-218
    • Yuan, X.M.1    Li, W.2    Brunk, U.T.3    Dalen, H.4    Chang, Y.H.5    Sevanian, A.6
  • 226
    • 84904733173 scopus 로고    scopus 로고
    • Synaptic membrane rafts: traffic lights for local neurotrophin signaling?
    • Zonta B., Minichiello L. Synaptic membrane rafts: traffic lights for local neurotrophin signaling?. Front. Synaptic Neurosci. 2013, 5(9).
    • (2013) Front. Synaptic Neurosci. , vol.5 , Issue.9
    • Zonta, B.1    Minichiello, L.2
  • 227
    • 80053557887 scopus 로고    scopus 로고
    • Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case control study
    • Zuliani G., Donnorso M.P., Bosi C., Passaro A., Dalla Nora E., Zurlo A., Bonetti F., Mozzi A.F., Cortese C. Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case control study. BMC Neurol. 2011, 11:121.
    • (2011) BMC Neurol. , vol.11 , pp. 121
    • Zuliani, G.1    Donnorso, M.P.2    Bosi, C.3    Passaro, A.4    Dalla Nora, E.5    Zurlo, A.6    Bonetti, F.7    Mozzi, A.F.8    Cortese, C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.