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Volumn 183, Issue 2, 2013, Pages 626-637

7-ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B

Author keywords

[No Author keywords available]

Indexed keywords

7 OXOCHOLESTEROL; ATG4B PROTEIN; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84880616033     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.04.028     Document Type: Article
Times cited : (109)

References (50)
  • 1
    • 35448981935 scopus 로고    scopus 로고
    • Autophagy: From phenomenology to molecular understanding in less than a decade
    • D.J. Klionsky Autophagy: from phenomenology to molecular understanding in less than a decade Nat Rev Mol Cell Biol 8 2007 931 937
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 931-937
    • Klionsky, D.J.1
  • 2
    • 36148960499 scopus 로고    scopus 로고
    • Induction of autophagy in neurite degeneration of mouse superior cervical ganglion neurons
    • Y. Yang, K. Fukui, T. Koike, and X. Zheng Induction of autophagy in neurite degeneration of mouse superior cervical ganglion neurons Eur J Neurosci 26 2007 2979 2988
    • (2007) Eur J Neurosci , vol.26 , pp. 2979-2988
    • Yang, Y.1    Fukui, K.2    Koike, T.3    Zheng, X.4
  • 3
    • 79959385996 scopus 로고    scopus 로고
    • Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
    • Z. Xie, K. Lau, B. Eby, P. Lozano, C. He, B. Pennington, H. Li, S. Rathi, Y. Dong, R. Tian, D. Kem, and M.H. Zou Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice Diabetes 60 2011 1770 1778
    • (2011) Diabetes , vol.60 , pp. 1770-1778
    • Xie, Z.1    Lau, K.2    Eby, B.3    Lozano, P.4    He, C.5    Pennington, B.6    Li, H.7    Rathi, S.8    Dong, Y.9    Tian, R.10    Kem, D.11    Zou, M.H.12
  • 4
    • 84876220612 scopus 로고    scopus 로고
    • Regulation of interplay between autophagy and apoptosis in the diabetic heart: New role of AMPK
    • M.H. Zou, and Z. Xie Regulation of interplay between autophagy and apoptosis in the diabetic heart: new role of AMPK Autophagy 9 2013 624 625
    • (2013) Autophagy , vol.9 , pp. 624-625
    • Zou, M.H.1    Xie, Z.2
  • 5
    • 80053393865 scopus 로고    scopus 로고
    • AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy
    • Z. Xie, C. He, and M.H. Zou AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy Autophagy 7 2011 1254 1255
    • (2011) Autophagy , vol.7 , pp. 1254-1255
    • Xie, Z.1    He, C.2    Zou, M.H.3
  • 6
    • 61949233502 scopus 로고    scopus 로고
    • Autophagy in atherosclerosis: A cell survival and death phenomenon with therapeutic potential
    • W. Martinet, and G.R. De Meyer Autophagy in atherosclerosis: a cell survival and death phenomenon with therapeutic potential Circ Res 104 2009 304 317
    • (2009) Circ Res , vol.104 , pp. 304-317
    • Martinet, W.1    De Meyer, G.R.2
  • 7
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis
    • R. Stocker, and J.F. Keaney Jr. Role of oxidative modifications in atherosclerosis Physiol Rev 84 2004 1381 1478
    • (2004) Physiol Rev , vol.84 , pp. 1381-1478
    • Stocker, R.1    Keaney, Jr.J.F.2
  • 8
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • R. Scherz-Shouval, E. Shvets, E. Fass, H. Shorer, L. Gil, and Z. Elazar Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 EMBO J 26 2007 1749 1760
    • (2007) EMBO J , vol.26 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6
  • 9
    • 0026686242 scopus 로고
    • Role of oxidized human plasma low density lipoproteins in atherosclerosis: Effects on smooth muscle cell proliferation
    • S. Chatterjee Role of oxidized human plasma low density lipoproteins in atherosclerosis: effects on smooth muscle cell proliferation Mol Cell Biochem 111 1992 143 147
    • (1992) Mol Cell Biochem , vol.111 , pp. 143-147
    • Chatterjee, S.1
  • 10
    • 0032890337 scopus 로고    scopus 로고
    • Oxysterols and atherosclerosis
    • A.J. Brown, and W. Jessup Oxysterols and atherosclerosis Atherosclerosis 142 1999 1 28
    • (1999) Atherosclerosis , vol.142 , pp. 1-28
    • Brown, A.J.1    Jessup, W.2
  • 11
    • 10644244534 scopus 로고    scopus 로고
    • 7-ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells
    • W. Martinet, B.M. De, D.M. Schrijvers, G.R. De Meyer, A.G. Herman, and M.M. Kockx 7-ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells Arterioscler Thromb Vasc Biol 24 2004 2296 2301
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2296-2301
    • Martinet, W.1    De, B.M.2    Schrijvers, D.M.3    De Meyer, G.R.4    Herman, A.G.5    Kockx, M.M.6
  • 12
    • 0037098448 scopus 로고    scopus 로고
    • 7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells
    • A. Ghelli, A.M. Porcelli, C. Zanna, and M. Rugolo 7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells Arch Biochem Biophys 402 2002 208 217
    • (2002) Arch Biochem Biophys , vol.402 , pp. 208-217
    • Ghelli, A.1    Porcelli, A.M.2    Zanna, C.3    Rugolo, M.4
  • 13
    • 0036683701 scopus 로고    scopus 로고
    • Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: Comparison with various pro-apoptotic chemicals
    • C. Miguet-Alfonsi, C. Prunet, S. Monier, G. Bessede, S. Lemaire-Ewing, A. Berthier, F. Menetrier, D. Neel, P. Gambert, and G. Lizard Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals Biochem Pharmacol 64 2002 527 541
    • (2002) Biochem Pharmacol , vol.64 , pp. 527-541
    • Miguet-Alfonsi, C.1    Prunet, C.2    Monier, S.3    Bessede, G.4    Lemaire-Ewing, S.5    Berthier, A.6    Menetrier, F.7    Neel, D.8    Gambert, P.9    Lizard, G.10
  • 14
    • 67650083087 scopus 로고    scopus 로고
    • Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis
    • Z. Xie, Y. Dong, J. Zhang, R. Scholz, D. Neumann, and M.H. Zou Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis Mol Cell Biol 29 2009 3582 3596
    • (2009) Mol Cell Biol , vol.29 , pp. 3582-3596
    • Xie, Z.1    Dong, Y.2    Zhang, J.3    Scholz, R.4    Neumann, D.5    Zou, M.H.6
  • 15
    • 39449096289 scopus 로고    scopus 로고
    • Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells
    • Z. Xie, Y. Dong, R. Scholz, D. Neumann, and M.H. Zou Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells Circulation 117 2008 952 962
    • (2008) Circulation , vol.117 , pp. 952-962
    • Xie, Z.1    Dong, Y.2    Scholz, R.3    Neumann, D.4    Zou, M.H.5
  • 17
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • M.W. Pfaffl A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 29 2001 e45
    • (2001) Nucleic Acids Res , vol.29 , pp. 45
    • Pfaffl, M.W.1
  • 18
    • 84875450015 scopus 로고    scopus 로고
    • Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes
    • C. He, H. Zhu, H. Li, M.H. Zou, and Z. Xie Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes Diabetes 62 2013 1270 1281
    • (2013) Diabetes , vol.62 , pp. 1270-1281
    • He, C.1    Zhu, H.2    Li, H.3    Zou, M.H.4    Xie, Z.5
  • 19
    • 77952073547 scopus 로고    scopus 로고
    • Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients
    • C. He, H.C. Choi, and Z. Xie Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients Am J Pathol 176 2010 2542 2549
    • (2010) Am J Pathol , vol.176 , pp. 2542-2549
    • He, C.1    Choi, H.C.2    Xie, Z.3
  • 20
    • 84869192260 scopus 로고    scopus 로고
    • Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice
    • H. Li, M. Xu, J. Lee, C. He, and Z. Xie Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice Am J Physiol Endocrinol Metab 303 2012 E1234 E1244
    • (2012) Am J Physiol Endocrinol Metab , vol.303
    • Li, H.1    Xu, M.2    Lee, J.3    He, C.4    Xie, Z.5
  • 21
    • 0031573401 scopus 로고    scopus 로고
    • A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: Applications in detecting the activity of phagocyte NADPH oxidase and other oxidases
    • M. Zhou, Z. Diwu, N. Panchuk-Voloshina, and R.P. Haugland A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases Anal Biochem 253 1997 162 168
    • (1997) Anal Biochem , vol.253 , pp. 162-168
    • Zhou, M.1    Diwu, Z.2    Panchuk-Voloshina, N.3    Haugland, R.P.4
  • 22
    • 77957656800 scopus 로고    scopus 로고
    • Synthetic substrates for measuring activity of autophagy proteases: Autophagins (Atg4)
    • C.W. Shu, M. Drag, M. Bekes, D. Zhai, G.S. Salvesen, and J.C. Reed Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4) Autophagy 6 2010 936 947
    • (2010) Autophagy , vol.6 , pp. 936-947
    • Shu, C.W.1    Drag, M.2    Bekes, M.3    Zhai, D.4    Salvesen, G.S.5    Reed, J.C.6
  • 23
    • 0342316532 scopus 로고    scopus 로고
    • Oxysterols: Modulators of cholesterol metabolism and other processes
    • G.J. Schroepfer Jr. Oxysterols: modulators of cholesterol metabolism and other processes Physiol Rev 80 2000 361 554
    • (2000) Physiol Rev , vol.80 , pp. 361-554
    • Schroepfer, Jr.G.J.1
  • 24
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • N. Mizushima, T. Yoshimori, and B. Levine Methods in mammalian autophagy research Cell 140 2010 313 326
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 25
    • 68049108407 scopus 로고    scopus 로고
    • N-acetylcysteine prevents neointima formation in experimental venous bypass grafts
    • G.R. de, A. Tintu, F. Stassen, G. Kloppenburg, C. Bruggeman, and E. Rouwet N-acetylcysteine prevents neointima formation in experimental venous bypass grafts Br J Surg 96 2009 941 950
    • (2009) Br J Surg , vol.96 , pp. 941-950
    • De, G.R.1    Tintu, A.2    Stassen, F.3    Kloppenburg, G.4    Bruggeman, C.5    Rouwet, E.6
  • 27
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • K. Bedard, and K.H. Krause The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology Physiol Rev 87 2007 245 313
    • (2007) Physiol Rev , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 28
    • 0035844030 scopus 로고    scopus 로고
    • Novel gp91(phox) homologues in vascular smooth muscle cells: Nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways
    • B. Lassegue, D. Sorescu, K. Szocs, Q. Yin, M. Akers, Y. Zhang, S.L. Grant, J.D. Lambeth, and K.K. Griendling Novel gp91(phox) homologues in vascular smooth muscle cells: nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways Circ Res 88 2001 888 894
    • (2001) Circ Res , vol.88 , pp. 888-894
    • Lassegue, B.1    Sorescu, D.2    Szocs, K.3    Yin, Q.4    Akers, M.5    Zhang, Y.6    Grant, S.L.7    Lambeth, J.D.8    Griendling, K.K.9
  • 35
    • 34548037901 scopus 로고    scopus 로고
    • Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
    • M. Hoyer-Hansen, and M. Jaattela Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium Cell Death Differ 14 2007 1576 1582
    • (2007) Cell Death Differ , vol.14 , pp. 1576-1582
    • Hoyer-Hansen, M.1    Jaattela, M.2
  • 36
    • 22244446505 scopus 로고    scopus 로고
    • The mammalian unfolded protein response
    • M. Schroder, and R.J. Kaufman The mammalian unfolded protein response Annu Rev Biochem 74 2005 739 789
    • (2005) Annu Rev Biochem , vol.74 , pp. 739-789
    • Schroder, M.1    Kaufman, R.J.2
  • 39
    • 78650882643 scopus 로고    scopus 로고
    • Reactive oxygen species and vascular biology: Implications in human hypertension
    • R.M. Touyz, and A.M. Briones Reactive oxygen species and vascular biology: implications in human hypertension Hypertens Res 34 2011 5 14
    • (2011) Hypertens Res , vol.34 , pp. 5-14
    • Touyz, R.M.1    Briones, A.M.2
  • 40
    • 0037423403 scopus 로고    scopus 로고
    • Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy
    • G. Marino, J.A. Uria, X.S. Puente, V. Quesada, J. Bordallo, and C. Lopez-Otin Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy J Biol Chem 278 2003 3671 3678
    • (2003) J Biol Chem , vol.278 , pp. 3671-3678
    • Marino, G.1    Uria, J.A.2    Puente, X.S.3    Quesada, V.4    Bordallo, J.5    Lopez-Otin, C.6
  • 42
    • 0034676037 scopus 로고    scopus 로고
    • The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
    • T. Kirisako, Y. Ichimura, H. Okada, Y. Kabeya, N. Mizushima, T. Yoshimori, M. Ohsumi, T. Takao, T. Noda, and Y. Ohsumi The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway J Cell Biol 151 2000 263 276
    • (2000) J Cell Biol , vol.151 , pp. 263-276
    • Kirisako, T.1    Ichimura, Y.2    Okada, H.3    Kabeya, Y.4    Mizushima, N.5    Yoshimori, T.6    Ohsumi, M.7    Takao, T.8    Noda, T.9    Ohsumi, Y.10
  • 44
    • 0037193474 scopus 로고    scopus 로고
    • DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
    • B. Inbal, S. Bialik, I. Sabanay, G. Shani, and A. Kimchi DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death J Cell Biol 157 2002 455 468
    • (2002) J Cell Biol , vol.157 , pp. 455-468
    • Inbal, B.1    Bialik, S.2    Sabanay, I.3    Shani, G.4    Kimchi, A.5
  • 45
    • 41149116150 scopus 로고    scopus 로고
    • Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells
    • B.G. Hill, P. Haberzettl, Y. Ahmed, S. Srivastava, and A. Bhatnagar Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells Biochem J 410 2008 525 534
    • (2008) Biochem J , vol.410 , pp. 525-534
    • Hill, B.G.1    Haberzettl, P.2    Ahmed, Y.3    Srivastava, S.4    Bhatnagar, A.5
  • 46
    • 33846259385 scopus 로고    scopus 로고
    • Autophagy of vascular smooth muscle cells in atherosclerotic lesions
    • G. Jia, G. Cheng, and D.K. Agrawal Autophagy of vascular smooth muscle cells in atherosclerotic lesions Autophagy 3 2007 63 64
    • (2007) Autophagy , vol.3 , pp. 63-64
    • Jia, G.1    Cheng, G.2    Agrawal, D.K.3
  • 47
    • 47249152694 scopus 로고    scopus 로고
    • Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells
    • W. Martinet, D.M. Schrijvers, J.P. Timmermans, and H. Bult Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells Br J Pharmacol 154 2008 1236 1246
    • (2008) Br J Pharmacol , vol.154 , pp. 1236-1246
    • Martinet, W.1    Schrijvers, D.M.2    Timmermans, J.P.3    Bult, H.4
  • 49
    • 22344444616 scopus 로고    scopus 로고
    • Does autophagy contribute to cell death?
    • J. Debnath, E.H. Baehrecke, and G. Kroemer Does autophagy contribute to cell death? Autophagy 1 2005 66 74
    • (2005) Autophagy , vol.1 , pp. 66-74
    • Debnath, J.1    Baehrecke, E.H.2    Kroemer, G.3
  • 50
    • 0013921992 scopus 로고
    • Atherosclerosis in rabbits. Architectural and subcellular alterations of smooth muscle cells of aortas in response to hyperlipemia
    • H. Imai, K.T. Lee, S. Pastori, E. Panlilio, R. Florentin, and W.A. Thomas Atherosclerosis in rabbits. Architectural and subcellular alterations of smooth muscle cells of aortas in response to hyperlipemia Exp Mol Pathol 5 1966 273 310
    • (1966) Exp Mol Pathol , vol.5 , pp. 273-310
    • Imai, H.1    Lee, K.T.2    Pastori, S.3    Panlilio, E.4    Florentin, R.5    Thomas, W.A.6


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