7β-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: Oxysterols-induced IL-8 secretion is calcium-dependent

Cell Biology and Toxicology

Volumn 25, Issue 2, 2009, Pages 127-139

  Lemaire Ewing, Stéphanie ^a,b   Berthier, Arnaud ^a,b   Royer, Marie Charlotte ^a,b   Logette, Emmanuelle ^a,b   Corcos, Laurent ^a,b   Bouchot, André ^a,b   Monier, Serge ^a,b   Prunet, Céline ^a,b   Raveneau, Magalie ^b   Rébé, Cédric ^b   Desrumaux, Catherine ^a,b   Lizard, Gérard ^a,b   Néel, Dominique ^c  

^a Institut Médical de Génétique et d Immunologie   (France)

^b UNIVERSITÉ DE BOURGOGNE   (France)

^c HÔPITAL DU BOCAGE   (France)

Author keywords

AP 1; C Fos; Calcium; IL 8; Monocytic cells; Oxysterols

Indexed keywords

25 HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; FLUO 3; INTERLEUKIN 8; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN C FOS; TRANSCRIPTION FACTOR AP 1; 25-HYDROXYCHOLESTEROL; CHOLEST 5 EN 3 BETA,7 ALPHA DIOL; CHOLEST-5-EN-3 BETA,7 ALPHA-DIOL; CHOLESTEROL DERIVATIVE; LOW DENSITY LIPOPROTEIN; NIFEDIPINE; OXIDIZED LOW DENSITY LIPOPROTEIN; VERAPAMIL;

APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL LINE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION; STAINING; WESTERN BLOTTING; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; MONOCYTE; SECRETION;

CALCIUM; CALCIUM CHANNEL BLOCKERS; CELL LINE; GENE EXPRESSION; HUMANS; HYDROXYCHOLESTEROLS; INTERLEUKIN-8; LIPOPROTEINS, LDL; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MONOCYTES; NIFEDIPINE; PROTO-ONCOGENE PROTEINS C-FOS; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1; VERAPAMIL;

EID: 65349111246     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10565-008-9063-0     Document Type: Article

References (34)

1. M Akhtar JL Watson A Nazli DM [tmp] McKay 2003 Bacterial DNA evokes epithelial IL-8 production by a MAPK-dependent, NFkB-independent pathway FASEB J 17 1319 21
2. P Angel M Karin 1991 The role of jun, Fos and the AP-1 complex in cell-proliferation and transformation Biochem Biophys Acta 1072 129 57 (Pubitemid 121007534)
3. 2+ oscillations, MAP-kinase activation and apoptosis in human aortic smooth muscle cells Atherosclerosis 153 23 35
4. A Berthier S Lemaire-Ewing C Prunet S Monier A Athias G Bessède JP Pais de Barros A Laubriet P Gambert G Lizard D Néel 2004 Involvement of a calcium-dependent dephosphorylation of BAD associated with the localization of Trpc-1 within lipid rafts in 7-ketocholesterol-induced THP-1 cell apoptosis Cell Death Differ 11 897 905 (Pubitemid 39139748)
5. A Berthier S Lemaire-Ewing C Prunet T Montange A Vejux JP Pais de Barros S Monier P Gambert G Lizard D Néel 2005 7-Ketocholesterol-induced apoptosis. Involvement of several pro-apoptotic but also anti-apoptotic calcium-dependent transduction pathways FEBS J 272 3093 104 (Pubitemid 40904696)
6. M Christ B Luu JE Mejia I Moosbrugger P Bischoff 1993 Apoptosis induced by oxysterols in murine lymphoma cells and in normal thymocytes Immunology 78 455 60 (Pubitemid 23076243)
7. SM Colles KC Irwin GM Chisolm 1996 Roles of multiple oxidized LDL lipids in cellular injury: dominance of 7 beta-hydroperoxycholesterol J Lipid Res 37 2018 28 (Pubitemid 26307682)
8. I Dikic G Tokiwa S Lev SA Courtneidge J Schlessinger 1996 A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation Nature 383 547 50 (Pubitemid 26346184)
9. HA Emanuel CA Hassel PB Addis SD Bergman JH Zavoral 1991 Plasma cholesterol oxidation products (oxysterols) in human subjects fed a meal rich in oxysterols J Food Sci 56 843 7
10. CS Hill R Treisman 1995 Transcriptional regulation by extracellular signals: mechanisms and specificity Cell 80 199 211
11. M Karin 1995 The regulation of AP-1 activity by mitogen-activated protein kinases J Biol Chem 270 16483 6
12. T Kikuchi K Hagiwara Y Honda K Gomi T Kobayashi H Takahashi Y Tokue A Watanabe T Nukiwa 2002 Clarithromycin supresses lipopolysaccharide-induced interleukin-8 production by human monocytes through AP-1 and NF-kappa B transcription factors J Antimicrob Chemother 49 745 55 (Pubitemid 34537634)
13. 2+-induced IL-8 production in human mast cells Cytokine 32 226 33 (Pubitemid 43148978)
14. AE Koch PJ Polverini SL Kunkel LA Harlow LA DiPietro VM Elner SG Elner RM Strieter 1992 Interleukin-8 as a macrophage-derived mediator of angiogenesis Science 258 1798 801 (Pubitemid 23087348)
15. CG Larsen AO Anderson E Appella JJ Oppenheim K Matsushima 1989 The neutrophil-activating protein (NAP-1) is also chemotactic for T-lymphocytes Science 243 1464 6 (Pubitemid 19087128)
16. S Lemaire-Ewing C Prunet T Montange A Vejux A Berthier G Bessède L Corcos P Gambert D Néel G Lizard 2005 Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols Cell Biol Toxicol 21 97 114 (Pubitemid 41253203)
17. Y Liu LM Hultén O Wiklund 1997 Macrophages isolated from human atherosclerotic plaques produce IL-8, and oxysterols may have a regulatory function for IL-8 production Arterioscler Thromb Vasc Biol 17 317 23 (Pubitemid 27098190)
18. G Lizard M Moisant C Cordelet S Monier P Gambert L Lagrost 1997 Induction of similar features of apoptosis in human and bovine vascular endothelial cells treated by 7-ketocholesterol J Pathol 183 330 8 (Pubitemid 27505220)
19. 2-terminal kinase p38s and extracellular signal-regulated kinase 5 Mol Cell Biol 19 4289 301 (Pubitemid 29242004)
20. 2+ Biochem J 269 513 19 (Pubitemid 20236047)
21. C Miguet-Alfonsi C Prunet S Monier G Bessède S Lemaire-Ewing A Berthier F Ménétrier D Néel P Gambert G Lizard 2002 Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7b-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals Biochem Pharmacol 64 527 41
22. S Monier M Samadi C Prunet M Denance A Laubriet A Athias A Berthier E Steinmetz G Jurgens A Negre-Salvayre G Bessede S Lemaire-Ewing D Néel P Gambert G Lizard 2003 Impairment of the cytototic and oxidative activities of 7 beta-hydroxycholesterol and 7-ketocholesterol by esterification with oleate Biochem Biophys Res Commun 303 814 24 (Pubitemid 36384928)
23. P Monje MJ Marinissen JS Gutkind 2003 Phosphorylation of the carboxyl-terminal transactivation domain of c-Fos by extracellular signal-regulated kinase mediates the transcriptional activation of AP-1 and cellular transformation induced by platelet-derived growth factor Mol Cell Biol 23 7030 43 (Pubitemid 37214669)
24. DW Morel JR Hessler GM Chisolm 1983 Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid J Lipid Res 24 1070 6
25. R Murakami F Kambe H Mitsuyama K Okumura T Murohara S Niwata R Yamamoto H Seo 2003 Cyclosporin A enhances interleukin-8 expression by inducing activator protein-1 in human aortic smooth muscle cells Arterioscler Thromb Vasc Biol 23 2034 40 (Pubitemid 37433197)
26. S Okamoto N Mukaida K Yasumoto N Rice Y Ishikawa H Horiguchi S Murakami K Matsushima 1994 The interleukin-8 AP-1 and kB-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization J Biol Chem 269 8582 9 (Pubitemid 24200286)
27. R Ross 1993 The pathogenesis of atherosclerosis a perspective for the1990s Nature 362 801 8
28. EK Rydberg L Salomonsson LM Hultén K Norén G Bondjers O Wiklund T Bjornheden BG Ohlsson 2003 Hypoxia increases 25-hydroxycholesterol- induced interleukin-8 secretion in human macrophages Atherosclerosis. 170 245 52 (Pubitemid 37377796)
29. SA Sharma MK Tummuru MJ Blaser LD Kerr 1998 Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappa B in gastric epithelial cells J Immunol 160 2401 7 (Pubitemid 28119924)
30. A Simonini M Moscucci DW Muller ER Bates FD Pagani MD Burdick RM Strieter 2000 IL-8 is an angiogenic factor in human coronary atherectomy tissue Circulation. 101 1519 26 (Pubitemid 30180887)
31. PK Smith RI Krohn GT Hermanson AK Mallia FH Gartner MD Provenzano EK Fujimoto NM Goeke BJ Olson DC Klenk 1985 (1985) Measurement of protein using bicinchonic acid Anal Biochem 150 76 85 (Pubitemid 16258399)
32. 2+-induced apoptosis through calcineurin dephosphorylation of BAD Science. 284 339 43 (Pubitemid 129523456)
33. J Yin X Chaufour C [tmp] McLachlan M [tmp] McGuire G White N King B Hambly 2000 Apoptosis of vascular smooth muscle cells induced by cholesterol and its oxides in vitro and in vivo Atherosclerosis. 148 365 74 (Pubitemid 30064468)
34. YM Zhu DA Bradbury L Pang AJ Knox 2003 Transcriptional regulation of Interleukin (IL)-8 by bradykinin in human airway smooth muscle cells involves prostanoid-dependent activation of AP-1 and nuclear factor (NF)-IL-6 and prostanoid-independent activation of NF-kappaB J Biol Chem 278 29366 75 (Pubitemid 36935854)