In vivo consequences of cholesterol-24S-hydroxylase (CYP46A1) inhibition by voriconazole on cholesterol homeostasis and function in the rat retina

Biochemical and Biophysical Research Communications

Volumn 446, Issue 3, 2014, Pages 775-781

  Fourgeux, Cynthia ^a   Martine, Lucy ^a   Acar, Niyazi ^a   Bron, Alain M ^a,b   Creuzot Garcher, Catherine P ^a,b   Bretillon, Lionel ^a  

^a CENTRE DES SCIENCES DU GOÛT ET DE L ALIMENTATION   (France)

^b DIJON UNIVERSITY HOSPITAL   (France)

Author keywords

Cholesterol homeostasis; CYP46A1; Glia; Retinal ganglion cell; Voriconazole

Indexed keywords

CHEMOKINE; CHOLESTEROL; CHOLESTEROL 24S HYDROXYLASE; CYTOKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MINOCYCLINE; MONOCYTE CHEMOTACTIC PROTEIN 1; OXYGENASE; UNCLASSIFIED DRUG; VORICONAZOLE;

ANIMAL EXPERIMENT; ARTICLE; B WAVE; BRAIN CORTEX; CELL ACTIVATION; CHOLESTEROL HOMEOSTASIS; CONTROLLED STUDY; ELECTRORETINOGRAM; ELECTRORETINOGRAPHY; ENZYME INHIBITION; GLIA CELL; HOMEOSTASIS; LIPID BLOOD LEVEL; MALE; MASS FRAGMENTOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA; RETINA GANGLION CELL; UPREGULATION;

CHOLESTEROL HOMEOSTASIS; CYP46A1; GLIA; RETINAL GANGLION CELL; VORICONAZOLE;

ANIMALS; CHOLESTEROL; CYTOKINES; ELECTRORETINOGRAPHY; ENZYME INHIBITORS; HOMEOSTASIS; HYDROXYCHOLESTEROLS; MALE; MICROGLIA; NERVE TISSUE PROTEINS; NEUROGLIA; PYRIMIDINES; RATS; RATS, WISTAR; RETINA; STEROID HYDROXYLASES; TRIAZOLES; UP-REGULATION;

EID: 84898808313     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.01.118     Document Type: Article

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