Sterculic acid antagonizes 7-ketocholesterol-mediated inflammation and inhibits choroidal neovascularization

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1821, Issue 4, 2012, Pages 637-646

  Huang, Jiahn Dar ^a   Amaral, Juan ^a   Lee, Jung Wha ^a   Larrayoz, Ignacio M ^a,b   Rodriguez, Ignacio R ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b CENTER FOR BIOMEDICAL RESEARCH OF LA RIOJA CIBIR   (Spain)

Author keywords

7 ketocholesterol; CHOP; ER stress; Inflammation; RPE; Sterculic acid

Indexed keywords

7 OXOCHOLESTEROL; FATTY ACID DERIVATIVE; STERCULIC ACID; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; INFLAMMATION; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; RETINA MACULA AGE RELATED DEGENERATION; SUBRETINAL NEOVASCULARIZATION;

ANIMALS; CELLS, CULTURED; CHOROIDAL NEOVASCULARIZATION; CYCLOPROPANES; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITORS; FATTY ACIDS; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOBLOTTING; INFLAMMATION; INFLAMMATION MEDIATORS; KETOCHOLESTEROLS; LASERS; MALE; RATS; RATS, INBRED BN; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTOR CHOP; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

RATTUS;

EID: 84862780347     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2012.01.013     Document Type: Article

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