Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1822, Issue 9, 2012, Pages 1475-1488

  Galea, Elena ^a,b   Launay, Nathalie ^c,d   Portero Otin, Manuel ^e   Ruiz, Montserrat ^c,d   Pamplona, Reinald ^e   Aubourg, Patrick ^f   Ferrer, Isidre ^c,d   Pujol, Aurora ^b,c,d  

^a INSTITUT DE NEUROCIÈNCIES   (Spain)

^b INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^c BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

^e UNIVERSITY OF LLEIDA   (Spain)

^f UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Adrenoleukodystrophy; Fatty acid; Metabolic failure; Mitochondria; Neurodegenerative disease; Oxidative stress

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; GLUTATHIONE; LEVODOPA; PIOGLITAZONE; RASAGILINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; VERY LONG CHAIN FATTY ACID;

ADRENOLEUKODYSTROPHY; ALZHEIMER DISEASE; BIOENERGY; CELL MEMBRANE; DRUG EFFICACY; ENERGY METABOLISM; GLYCOLYSIS; HOMEOSTASIS; HUMAN; HUNTINGTON CHOREA; INFLAMMATION; MITOCHONDRION; NERVE FIBER DEGENERATION; NONHUMAN; OXIDATION REDUCTION POTENTIAL; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PEROXISOME; PRIORITY JOURNAL; REVIEW;

ADRENOLEUKODYSTROPHY; ANIMALS; ANTIOXIDANTS; AXONS; CELL MEMBRANE; HUMANS; INFLAMMATION; MITOCHONDRIA; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; PEROXISOMES; REACTIVE OXYGEN SPECIES;

ANIMALIA; MUS;

EID: 84864032314     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2012.02.005     Document Type: Review

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