Fast LC-MS/MS analysis of free oxysterols derived from reactive oxygen species in human plasma and carotid plaque

Clinica Chimica Acta

Volumn 425, Issue , 2013, Pages 3-8

  Helmschrodt, Christin ^a,b   Becker, Susen ^a,b   Schröter, Jenny ^a   Hecht, Max ^a   Aust, Gabriela ^b   Thiery, Joachim ^a,b   Ceglarek, Uta ^a,b  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Atherosclerotic plaque; Fast chromatography; Free oxysterol; Oxysterol; Reactive oxygen species; Tandem mass spectrometry

Indexed keywords

5,6 ALPHA EPOXYCHOLESTEROL; 5,6 BETA EPOXYCHOLESTEROL; 7 OXOCHOLESTEROL; 7ALPHA HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; CHOLESTANETRIOL; CHOLESTEROL; OXYSTEROL; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD SAMPLING; CAROTID ATHEROSCLEROSIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIMIT OF DETECTION; LIPID BLOOD LEVEL; LIPID COMPOSITION; LIPID PEROXIDATION; LIQUID LIQUID EXTRACTION; MALE; MIDDLE AGED; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RELIABILITY; SEPARATION TECHNIQUE; STEROL ANALYSIS; TANDEM MASS SPECTROMETRY;

-HYDROXYCHOLESTEROL; -OHC; 5,6-Α-EC; 5,6-Α-EPOXYCHOLESTEROL; 5,6-Β-EC; 5,6-Β-EPOXYCHOLESTEROL; 7-KC; 7-KETOCHOLESTEROL; 7-Α- AND 7-Β-HYDROXYCHOLESTEROL; 7-Α/Β-OHC; APCI; ATHEROSCLEROTIC PLAQUE; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION; BHT; BUTYLATED HYDROXYTOLUENE; CAROTID ENDARTERECTOMY; CE; CEA; CHOLESTANE-3Β,5Α,6Β-TRIOL; CID; COEFFICIENT OF VARIATION; COLLISION ENERGY; COLLISION EXIT POTENTIAL; COLLISION INDUCED DISSOCIATION; CV; CXP; DECLUSTERING POTENTIAL; DP; EP; EXTENSIONS POTENTIAL; FAST CHROMATOGRAPHY; FREE OXYSTEROL; GAS CHROMATOGRAPHY MASS SPECTROMETRY; GC-MS; HCL; HIGH CONCENTRATED QUALITY CONTROL; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HPLC; HQC; HYDROCHLORIC ACID; LC; LC-MS/MS; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; LIQUID-LIQUID EXTRACTION; LLE; LLOQ; LOD; LOW CONCENTRATED QUALITY CONTROL; LOWER LEVEL OF QUANTIFICATION; LQC; MEDIUM CONCENTRATED QUALITY CONTROL; MQC; MRM; MULTIPLE REACTING MONITORING; NA(2)SO(4); NAOH; NATIVE QUALITY CONTROL; NQC; OXYSTEROL; PATHOLOGICAL CONCENTRATED QUALITY CONTROL; PQC; QC; QUALITY CONTROLS; REACTIVE OXYGEN SPECIES; ROS; S/N; SIGNAL-TO-NOISE RATIO; SODIUM HYDROXIDE; SODIUM SULFATE; SOLID PHASE EXTRACTION; SPE; TANDEM MASS SPECTROMETRY; TRIOL;

CALIBRATION; CAROTID ARTERIES; CHOLESTEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; FEMALE; HUMANS; HYDROXYCHOLESTEROLS; ISOMERISM; KETOCHOLESTEROLS; LIMIT OF DETECTION; LIQUID-LIQUID EXTRACTION; MALE; MASS SPECTROMETRY; MIDDLE AGED; PLAQUE, ATHEROSCLEROTIC; REACTIVE OXYGEN SPECIES; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84881234258     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2013.06.022     Document Type: Article

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