-
1
-
-
65349085751
-
Clinical investigations in primary care
-
de Souza, L. C., Sarazin, M., Goetz, C., and Dubois, B. (2009) Clinical investigations in primary care Front. Neurol. Neurosci. 24, 1-11
-
(2009)
Front. Neurol. Neurosci.
, vol.24
, pp. 1-11
-
-
De Souza, L.C.1
Sarazin, M.2
Goetz, C.3
Dubois, B.4
-
2
-
-
0035066332
-
Alzheimers disease: Genes, proteins, and therapy
-
Selkoe, D. J. (2001) Alzheimers disease: genes, proteins, and therapy Physiol. Rev. 81, 741-766
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
3
-
-
0023248681
-
Perspectives on the etiology of Alzheimers disease
-
Mozar, H. N., Bal, D. G., and Howard, J. T. (1987) Perspectives on the etiology of Alzheimers disease JAMA, J. Am. Med. Assoc. 257, 1503-1507
-
(1987)
JAMA, J. Am. Med. Assoc.
, vol.257
, pp. 1503-1507
-
-
Mozar, H.N.1
Bal, D.G.2
Howard, J.T.3
-
4
-
-
2342609768
-
State-specific projections through 2025 of Alzheimer disease prevalence
-
Hebert, L. E., Scherr, P. A., Bienias, J. L., Bennett, D. A., and Evans, D. A. (2004) State-specific projections through 2025 of Alzheimer disease prevalence Neurology 62, 1645
-
(2004)
Neurology
, vol.62
, pp. 1645
-
-
Hebert, L.E.1
Scherr, P.A.2
Bienias, J.L.3
Bennett, D.A.4
Evans, D.A.5
-
5
-
-
80054923695
-
Pharmacological treatment of Alzheimer disease
-
Massoud, F. and Leger, G. C. (2011) Pharmacological treatment of Alzheimer disease Can. J. Psychiatry 56, 579-588
-
(2011)
Can. J. Psychiatry
, vol.56
, pp. 579-588
-
-
Massoud, F.1
Leger, G.C.2
-
6
-
-
0141756129
-
Pharmacologic treatment of Alzheimers disease: An update
-
DeLaGarza, V. W. (2003) Pharmacologic treatment of Alzheimers disease: an update Am. Fam. Physician 68, 1365-1372
-
(2003)
Am. Fam. Physician
, vol.68
, pp. 1365-1372
-
-
Delagarza, V.W.1
-
7
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak, H. and Braak, E. (1991) Neuropathological stageing of Alzheimer-related changes Acta Neuropathol. 82, 239-259
-
(1991)
Acta Neuropathol.
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
8
-
-
78149488153
-
Amyloid-independent mechanisms in Alzheimers disease pathogenesis
-
Pimplikar, S. W., Nixon, R. A., Robakis, N. K., Shen, J., and Tsai, L. H. (2010) Amyloid-independent mechanisms in Alzheimers disease pathogenesis J. Neurosci. 30, 14946-14954
-
(2010)
J. Neurosci.
, vol.30
, pp. 14946-14954
-
-
Pimplikar, S.W.1
Nixon, R.A.2
Robakis, N.K.3
Shen, J.4
Tsai, L.H.5
-
9
-
-
0042508791
-
Neuropathologic changes in Alzheimers disease
-
Wenk, G. L. (2003) Neuropathologic changes in Alzheimers disease J. Clin. Psychiatry 64 (Suppl 9) 7-10
-
(2003)
J. Clin. Psychiatry
, vol.64
, Issue.SUPPL. 9
, pp. 7-10
-
-
Wenk, G.L.1
-
10
-
-
0028213511
-
Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: A quantitative evaluation of a one-year autopsy population from a geriatric hospital
-
Bouras, C., Hof, P. R., Giannakopoulos, P., Michel, J. P., and Morrison, J. H. (1994) Regional distribution of neurofibrillary tangles and senile plaques in the cerebral cortex of elderly patients: a quantitative evaluation of a one-year autopsy population from a geriatric hospital Cereb. Cortex 4, 138-150
-
(1994)
Cereb. Cortex
, vol.4
, pp. 138-150
-
-
Bouras, C.1
Hof, P.R.2
Giannakopoulos, P.3
Michel, J.P.4
Morrison, J.H.5
-
11
-
-
0030005625
-
Tau protein and the neurofibrillary pathology of Alzheimers disease
-
Goedert, M. (1996) Tau protein and the neurofibrillary pathology of Alzheimers disease Ann. N.Y. Acad. Sci. 777, 121-131
-
(1996)
Ann. N.Y. Acad. Sci.
, vol.777
, pp. 121-131
-
-
Goedert, M.1
-
12
-
-
2942561028
-
The importance of neuritic plaques and tangles to the development and evolution of AD
-
Tiraboschi, P., Hansen, L. A., Thal, L. J., and Corey-Bloom, J. (2004) The importance of neuritic plaques and tangles to the development and evolution of AD Neurology 62, 1984-1989
-
(2004)
Neurology
, vol.62
, pp. 1984-1989
-
-
Tiraboschi, P.1
Hansen, L.A.2
Thal, L.J.3
Corey-Bloom, J.4
-
13
-
-
33749177143
-
A hundred years of Alzheimers disease research
-
Hardy, J. (2006) A hundred years of Alzheimers disease research Neuron 52, 3-13
-
(2006)
Neuron
, vol.52
, pp. 3-13
-
-
Hardy, J.1
-
14
-
-
0037135111
-
The amyloid hypothesis of Alzheimers disease: Progress and problems on the road to therapeutics
-
Hardy, J. and Selkoe, D. J. (2002) The amyloid hypothesis of Alzheimers disease: progress and problems on the road to therapeutics Science 297, 353-356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
15
-
-
0345636018
-
Amyloid deposition in the hippocampus and entorhinal cortex: Quantitative analysis of a transgenic mouse model
-
Reilly, J. F., Games, D., Rydel, R. E., Freedman, S., Schenk, D., Young, W. G., Morrison, J. H., and Bloom, F. E. (2003) Amyloid deposition in the hippocampus and entorhinal cortex: quantitative analysis of a transgenic mouse model Proc. Natl. Acad. Sci. U.S.A. 100, 4837-4842
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 4837-4842
-
-
Reilly, J.F.1
Games, D.2
Rydel, R.E.3
Freedman, S.4
Schenk, D.5
Young, W.G.6
Morrison, J.H.7
Bloom, F.E.8
-
16
-
-
0022401271
-
Quantitative morphology and regional and laminar distributions of senile plaques in Alzheimers disease
-
Rogers, J. and Morrison, J. H. (1985) Quantitative morphology and regional and laminar distributions of senile plaques in Alzheimers disease J. Neurosci. 5, 2801-2808
-
(1985)
J. Neurosci.
, vol.5
, pp. 2801-2808
-
-
Rogers, J.1
Morrison, J.H.2
-
17
-
-
33645038471
-
A specific amyloid-beta protein assembly in the brain impairs memory
-
Lesne, S., Koh, M. T., Kotilinek, L., Kayed, R., Glabe, C. G., Yang, A., Gallagher, M., and Ashe, K. H. (2006) A specific amyloid-beta protein assembly in the brain impairs memory Nature 440, 352-357
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesne, S.1
Koh, M.T.2
Kotilinek, L.3
Kayed, R.4
Glabe, C.G.5
Yang, A.6
Gallagher, M.7
Ashe, K.H.8
-
18
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer disease and Down syndrome
-
Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L., and Beyreuther, K. (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome Proc. Natl. Acad. Sci. U.S.A. 82, 4245-4249
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
Multhaup, G.4
McDonald, B.L.5
Beyreuther, K.6
-
19
-
-
0034521392
-
Clearance of Alzheimers amyloid-beta(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
-
Shibata, M., Yamada, S., Kumar, S. R., Calero, M., Bading, J., Frangione, B., Holtzman, D. M., Miller, C. A., Strickland, D. K., Ghiso, J., and Zlokovic, B. V. (2000) Clearance of Alzheimers amyloid-beta(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier J. Clin. Invest. 106, 1489-1499
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1489-1499
-
-
Shibata, M.1
Yamada, S.2
Kumar, S.R.3
Calero, M.4
Bading, J.5
Frangione, B.6
Holtzman, D.M.7
Miller, C.A.8
Strickland, D.K.9
Ghiso, J.10
Zlokovic, B.V.11
-
20
-
-
0036462453
-
Alzheimers disease and the amyloid cascade hypothesis: Ten years on
-
Sommer, B. (2002) Alzheimers disease and the amyloid cascade hypothesis: ten years on Curr. Opin. Pharmacol. 2, 87-92
-
(2002)
Curr. Opin. Pharmacol.
, vol.2
, pp. 87-92
-
-
Sommer, B.1
-
21
-
-
11344265672
-
Interactions between beta-amyloid and central cholinergic neurons: Implications for Alzheimers disease
-
Kar, S., Slowikowski, S. P., Westaway, D., and Mount, H. T. (2004) Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimers disease J. Psychiatry Neurosci. 29, 427-441
-
(2004)
J. Psychiatry Neurosci.
, vol.29
, pp. 427-441
-
-
Kar, S.1
Slowikowski, S.P.2
Westaway, D.3
Mount, H.T.4
-
22
-
-
0029896354
-
Mechanisms of neuronal degeneration in Alzheimers disease
-
Yankner, B. A. (1996) Mechanisms of neuronal degeneration in Alzheimers disease Neuron 16, 921-932
-
(1996)
Neuron
, vol.16
, pp. 921-932
-
-
Yankner, B.A.1
-
23
-
-
78650678688
-
Decreased clearance of CNS beta-amyloid in Alzheimers disease
-
Mawuenyega, K. G., Sigurdson, W., Ovod, V., Munsell, L., Kasten, T., Morris, J. C., Yarasheski, K. E., and Bateman, R. J. (2010) Decreased clearance of CNS beta-amyloid in Alzheimers disease Science 330, 1774
-
(2010)
Science
, vol.330
, pp. 1774
-
-
Mawuenyega, K.G.1
Sigurdson, W.2
Ovod, V.3
Munsell, L.4
Kasten, T.5
Morris, J.C.6
Yarasheski, K.E.7
Bateman, R.J.8
-
24
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimers disease locus
-
Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D. M., Oshima, J., Pettingell, W. H., Yu, C. E., Jondro, P. D., Schmidt, S. D., and Wang, K. 1995, Candidate gene for the chromosome 1 familial Alzheimers disease locus Science 269, 973-977
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
Yu, C.E.7
Jondro, P.D.8
Schmidt, S.D.9
Wang, K.10
-
25
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimers disease
-
Sherrington, R., Rogaev, E. I., Liang, Y., Rogaeva, E. A., Levesque, G., Ikeda, M., Chi, H., Lin, C., Li, G., Holman, K., Tsuda, T., Mar, L., Foncin, J. F., Bruni, A. C., Montesi, M. P., Sorbi, S., Rainero, I., Pinessi, L., Nee, L., Chumakov, I., Pollen, D., Brookes, A., Sanseau, P., Polinsky, R. J., Wasco, W., Da Silva, H. A., Haines, J. L., Perkicak-Vance, M. A., Tanzi, R. E., Roses, A. D., Fraser, P. E., Rommens, J. M., and St George-Hyslop, P. H. (1995) Cloning of a gene bearing missense mutations in early-onset familial Alzheimers disease Nature 375, 754-760
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Rainero, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Pollen, D.21
Brookes, A.22
Sanseau, P.23
Polinsky, R.J.24
Wasco, W.25
Da Silva, H.A.26
Haines, J.L.27
Perkicak-Vance, M.A.28
Tanzi, R.E.29
Roses, A.D.30
Fraser, P.E.31
Rommens, J.M.32
St George-Hyslop, P.H.33
more..
-
26
-
-
33748753481
-
Clearance of amyloid-beta in Alzheimers disease: Progress, problems and perspectives
-
Wang, Y. J., Zhou, H. D., and Zhou, X. F. (2006) Clearance of amyloid-beta in Alzheimers disease: progress, problems and perspectives Drug Discovery Today 11, 931-938
-
(2006)
Drug Discovery Today
, vol.11
, pp. 931-938
-
-
Wang, Y.J.1
Zhou, H.D.2
Zhou, X.F.3
-
27
-
-
0036160489
-
Genotype and phenotype in Alzheimers disease
-
Holmes, C. (2002) Genotype and phenotype in Alzheimers disease Br. J. Psychiatry 180, 131-134
-
(2002)
Br. J. Psychiatry
, vol.180
, pp. 131-134
-
-
Holmes, C.1
-
28
-
-
84863393540
-
Blood-brain barrier P-glycoprotein function in Alzheimers disease
-
van Assema, D. M., Lubberink, M., Bauer, M., van der Flier, W. M., Schuit, R. C., Windhorst, A. D., Comans, E. F., Hoetjes, N. J., Tolboom, N., Langer, O., Muller, M., Scheltens, P., Lammertsma, A. A., and van Berckel, B. N. (2012) Blood-brain barrier P-glycoprotein function in Alzheimers disease Brain 135, 181-189
-
(2012)
Brain
, vol.135
, pp. 181-189
-
-
Van Assema, D.M.1
Lubberink, M.2
Bauer, M.3
Van Der Flier, W.M.4
Schuit, R.C.5
Windhorst, A.D.6
Comans, E.F.7
Hoetjes, N.J.8
Tolboom, N.9
Langer, O.10
Muller, M.11
Scheltens, P.12
Lammertsma, A.A.13
Van Berckel, B.N.14
-
29
-
-
41149157623
-
Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimers disease
-
Weller, R. O., Subash, M., Preston, S. D., Mazanti, I., and Carare, R. O. (2008) Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimers disease Brain Pathol. 18, 253-266
-
(2008)
Brain Pathol.
, vol.18
, pp. 253-266
-
-
Weller, R.O.1
Subash, M.2
Preston, S.D.3
Mazanti, I.4
Carare, R.O.5
-
30
-
-
70349338659
-
The pre-capillary segment of the blood-brain barrier and its relation to perivascular drainage in Alzheimers disease and small vessel disease
-
Thal, D. R. (2009) The pre-capillary segment of the blood-brain barrier and its relation to perivascular drainage in Alzheimers disease and small vessel disease TheScientificWorldJournal 9, 557-563
-
(2009)
TheScientificWorldJournal
, vol.9
, pp. 557-563
-
-
Thal, D.R.1
-
31
-
-
0013117931
-
The role of drug transporters at the blood-brain barrier
-
de Boer, A. G., van der Sandt, I. C., and Gaillard, P. J. (2003) The role of drug transporters at the blood-brain barrier Annu. Rev. Pharmacol. Toxicol. 43, 629-656
-
(2003)
Annu. Rev. Pharmacol. Toxicol.
, vol.43
, pp. 629-656
-
-
De Boer, A.G.1
Van Der Sandt, I.C.2
Gaillard, P.J.3
-
32
-
-
12344262373
-
Blood-brain barrier active efflux transporters: ATP-binding cassette gene family
-
Loscher, W. and Potschka, H. (2005) Blood-brain barrier active efflux transporters: ATP-binding cassette gene family NeuroRx 2, 86-98
-
(2005)
NeuroRx
, vol.2
, pp. 86-98
-
-
Loscher, W.1
Potschka, H.2
-
33
-
-
63249115678
-
The blood-brain barrier in brain homeostasis and neurological diseases
-
Weiss, N., Miller, F., Cazaubon, S., and Couraud, P. O. (2009) The blood-brain barrier in brain homeostasis and neurological diseases Biochim. Biophys. Acta 1788, 842-857
-
(2009)
Biochim. Biophys. Acta
, vol.1788
, pp. 842-857
-
-
Weiss, N.1
Miller, F.2
Cazaubon, S.3
Couraud, P.O.4
-
34
-
-
0034500036
-
The blood-brain barrier and oncology: New insights into function and modulation
-
Bart, J., Groen, H. J., Hendrikse, N. H., van der Graaf, W. T., Vaalburg, W., and de Vries, E. G. (2000) The blood-brain barrier and oncology: new insights into function and modulation Cancer Treat. Rev. 26, 449-462
-
(2000)
Cancer Treat. Rev.
, vol.26
, pp. 449-462
-
-
Bart, J.1
Groen, H.J.2
Hendrikse, N.H.3
Van Der Graaf, W.T.4
Vaalburg, W.5
De Vries, E.G.6
-
35
-
-
13244298981
-
Potential role of drug transporters in the pathogenesis of medically intractable epilepsy
-
Kwan, P. and Brodie, M. J. (2005) Potential role of drug transporters in the pathogenesis of medically intractable epilepsy Epilepsia 46, 224-235
-
(2005)
Epilepsia
, vol.46
, pp. 224-235
-
-
Kwan, P.1
Brodie, M.J.2
-
36
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
Gottesman, M. M., Fojo, T., and Bates, S. E. (2002) Multidrug resistance in cancer: role of ATP-dependent transporters Nat. Rev. Cancer 2, 48-58
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
37
-
-
79954483841
-
Transport of drugs across the blood-brain barrier in Alzheimers disease
-
Nicolazzo, J. A. and Mehta, D. C. (2010) Transport of drugs across the blood-brain barrier in Alzheimers disease Ther. Delivery 1, 595-611
-
(2010)
Ther. Delivery
, vol.1
, pp. 595-611
-
-
Nicolazzo, J.A.1
Mehta, D.C.2
-
38
-
-
79959863415
-
Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: Investigation of P-glycoprotein as a novel therapeutic target for Alzheimers disease
-
Abuznait, A. H., Cain, C., Ingram, D., Burk, D., and Kaddoumi, A. (2011) Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimers disease J. Pharm. Pharmacol. 63, 1111-1118
-
(2011)
J. Pharm. Pharmacol.
, vol.63
, pp. 1111-1118
-
-
Abuznait, A.H.1
Cain, C.2
Ingram, D.3
Burk, D.4
Kaddoumi, A.5
-
39
-
-
63349089378
-
P-gp transporter and its role in neurodegenerative diseases
-
Rapposelli, S., Digiacomo, M., and Balsamo, A. (2009) P-gp transporter and its role in neurodegenerative diseases Curr. Top. Med. Chem. 9, 209-217
-
(2009)
Curr. Top. Med. Chem.
, vol.9
, pp. 209-217
-
-
Rapposelli, S.1
Digiacomo, M.2
Balsamo, A.3
-
40
-
-
67349142021
-
Neurovascular mechanisms and blood-brain barrier disorder in Alzheimers disease
-
Bell, R. D. and Zlokovic, B. V. (2009) Neurovascular mechanisms and blood-brain barrier disorder in Alzheimers disease Acta Neuropathol. 118, 103-113
-
(2009)
Acta Neuropathol.
, vol.118
, pp. 103-113
-
-
Bell, R.D.1
Zlokovic, B.V.2
-
41
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut, F., Tsuruo, T., Hamada, H., Gottesman, M. M., Pastan, I., and Willingham, M. C. (1987) Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues Proc. Natl. Acad. Sci. U.S.A. 84, 7735-7738
-
(1987)
Proc. Natl. Acad. Sci. U.S.A.
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
42
-
-
0030823912
-
P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain
-
Beaulieu, E., Demeule, M., Ghitescu, L., and Beliveau, R. (1997) P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain Biochem. J. 326 (Pt 2) 539-544
-
(1997)
Biochem. J.
, vol.326
, Issue.PART 2
, pp. 539-544
-
-
Beaulieu, E.1
Demeule, M.2
Ghitescu, L.3
Beliveau, R.4
-
43
-
-
46949098349
-
Modulation of P-glycoprotein at the blood-brain barrier: Opportunities to improve central nervous system pharmacotherapy
-
Miller, D. S., Bauer, B., and Hartz, A. M. (2008) Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy Pharmacol. Rev. 60, 196-209
-
(2008)
Pharmacol. Rev.
, vol.60
, pp. 196-209
-
-
Miller, D.S.1
Bauer, B.2
Hartz, A.M.3
-
44
-
-
0034214069
-
Functional expression of P-glycoprotein and multidrug resistance-associated protein (Mrp1) in primary cultures of rat astrocytes
-
Decleves, X., Regina, A., Laplanche, J. L., Roux, F., Boval, B., Launay, J. M., and Scherrmann, J. M. (2000) Functional expression of P-glycoprotein and multidrug resistance-associated protein (Mrp1) in primary cultures of rat astrocytes J. Neurosci. Res. 60, 594-601
-
(2000)
J. Neurosci. Res.
, vol.60
, pp. 594-601
-
-
Decleves, X.1
Regina, A.2
Laplanche, J.L.3
Roux, F.4
Boval, B.5
Launay, J.M.6
Scherrmann, J.M.7
-
45
-
-
2442673340
-
Involvement of P-glycoprotein in the transport of saquinavir and indinavir in rat brain microvessel endothelial and microglia cell lines
-
Ronaldson, P. T., Lee, G., Dallas, S., and Bendayan, R. (2004) Involvement of P-glycoprotein in the transport of saquinavir and indinavir in rat brain microvessel endothelial and microglia cell lines Pharm. Res. 21, 811-818
-
(2004)
Pharm. Res.
, vol.21
, pp. 811-818
-
-
Ronaldson, P.T.1
Lee, G.2
Dallas, S.3
Bendayan, R.4
-
46
-
-
2042451616
-
Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures
-
Ronaldson, P. T., Bendayan, M., Gingras, D., Piquette-Miller, M., and Bendayan, R. (2004) Cellular localization and functional expression of P-glycoprotein in rat astrocyte cultures J. Neurochem. 89, 788-800
-
(2004)
J. Neurochem.
, vol.89
, pp. 788-800
-
-
Ronaldson, P.T.1
Bendayan, M.2
Gingras, D.3
Piquette-Miller, M.4
Bendayan, R.5
-
47
-
-
59849129439
-
ABC transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) expression in the developing human CNS
-
Daood, M., Tsai, C., Ahdab-Barmada, M., and Watchko, J. F. (2008) ABC transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) expression in the developing human CNS Neuropediatrics 39, 211-218
-
(2008)
Neuropediatrics
, vol.39
, pp. 211-218
-
-
Daood, M.1
Tsai, C.2
Ahdab-Barmada, M.3
Watchko, J.F.4
-
48
-
-
16244367423
-
Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables
-
Volk, H., Potschka, H., and Loscher, W. (2005) Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables J. Histochem. Cytochem. 53, 517-531
-
(2005)
J. Histochem. Cytochem.
, vol.53
, pp. 517-531
-
-
Volk, H.1
Potschka, H.2
Loscher, W.3
-
49
-
-
0347033287
-
Expression and cellular distribution of multidrug transporter proteins in two major causes of medically intractable epilepsy: Focal cortical dysplasia and glioneuronal tumors
-
Aronica, E., Gorter, J. A., Jansen, G. H., van Veelen, C. W., van Rijen, P. C., Leenstra, S., Ramkema, M., Scheffer, G. L., Scheper, R. J., and Troost, D. (2003) Expression and cellular distribution of multidrug transporter proteins in two major causes of medically intractable epilepsy: focal cortical dysplasia and glioneuronal tumors Neuroscience 118, 417-429
-
(2003)
Neuroscience
, vol.118
, pp. 417-429
-
-
Aronica, E.1
Gorter, J.A.2
Jansen, G.H.3
Van Veelen, C.W.4
Van Rijen, P.C.5
Leenstra, S.6
Ramkema, M.7
Scheffer, G.L.8
Scheper, R.J.9
Troost, D.10
-
50
-
-
34547699433
-
Expression and cellular distribution of multidrug resistance-related proteins in patients with focal cortical dysplasia
-
Ak, H., Ay, B., Tanriverdi, T., Sanus, G. Z., Is, M., Sar, M., Oz, B., Ozkara, C., Ozyurt, E., and Uzan, M. (2007) Expression and cellular distribution of multidrug resistance-related proteins in patients with focal cortical dysplasia Seizure 16, 493-503
-
(2007)
Seizure
, vol.16
, pp. 493-503
-
-
Ak, H.1
Ay, B.2
Tanriverdi, T.3
Sanus, G.Z.4
Is, M.5
Sar, M.6
Oz, B.7
Ozkara, C.8
Ozyurt, E.9
Uzan, M.10
-
51
-
-
1242298755
-
Transient expression of MDR-1/P-glycoprotein in a model of partial cortical devascularization
-
Ramos, A. J., Lazarowski, A., Villar, M. J., and Brusco, A. (2004) Transient expression of MDR-1/P-glycoprotein in a model of partial cortical devascularization Cell. Mol. Neurobiol. 24, 101-107
-
(2004)
Cell. Mol. Neurobiol.
, vol.24
, pp. 101-107
-
-
Ramos, A.J.1
Lazarowski, A.2
Villar, M.J.3
Brusco, A.4
-
52
-
-
0035112889
-
Beta-Amyloid efflux mediated by p-glycoprotein
-
Lam, F. C., Liu, R., Lu, P., Shapiro, A. B., Renoir, J. M., Sharom, F. J., and Reiner, P. B. (2001) beta-Amyloid efflux mediated by p-glycoprotein J. Neurochem. 76, 1121-1128
-
(2001)
J. Neurochem.
, vol.76
, pp. 1121-1128
-
-
Lam, F.C.1
Liu, R.2
Lu, P.3
Shapiro, A.B.4
Renoir, J.M.5
Sharom, F.J.6
Reiner, P.B.7
-
53
-
-
35148859731
-
MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimers amyloid-beta peptides - Implications for the mechanisms of Abeta clearance at the blood-brain barrier
-
Kuhnke, D., Jedlitschky, G., Grube, M., Krohn, M., Jucker, M., Mosyagin, I., Cascorbi, I., Walker, L. C., Kroemer, H. K., Warzok, R. W., and Vogelgesang, S. (2007) MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimers amyloid-beta peptides - implications for the mechanisms of Abeta clearance at the blood-brain barrier Brain Pathol. 17, 347-353
-
(2007)
Brain Pathol.
, vol.17
, pp. 347-353
-
-
Kuhnke, D.1
Jedlitschky, G.2
Grube, M.3
Krohn, M.4
Jucker, M.5
Mosyagin, I.6
Cascorbi, I.7
Walker, L.C.8
Kroemer, H.K.9
Warzok, R.W.10
Vogelgesang, S.11
-
54
-
-
27644489474
-
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model
-
Cirrito, J. R., Deane, R., Fagan, A. M., Spinner, M. L., Parsadanian, M., Finn, M. B., Jiang, H., Prior, J. L., Sagare, A., Bales, K. R., Paul, S. M., Zlokovic, B. V., Piwnica-Worms, D., and Holtzman, D. M. (2005) P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model J. Clin. Invest. 115, 3285-3290
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 3285-3290
-
-
Cirrito, J.R.1
Deane, R.2
Fagan, A.M.3
Spinner, M.L.4
Parsadanian, M.5
Finn, M.B.6
Jiang, H.7
Prior, J.L.8
Sagare, A.9
Bales, K.R.10
Paul, S.M.11
Zlokovic, B.V.12
Piwnica-Worms, D.13
Holtzman, D.M.14
-
55
-
-
0036797713
-
Deposition of Alzheimers beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans
-
Vogelgesang, S., Cascorbi, I., Schroeder, E., Pahnke, J., Kroemer, H. K., Siegmund, W., Kunert-Keil, C., Walker, L. C., and Warzok, R. W. (2002) Deposition of Alzheimers beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans Pharmacogenetics 12, 535-541
-
(2002)
Pharmacogenetics
, vol.12
, pp. 535-541
-
-
Vogelgesang, S.1
Cascorbi, I.2
Schroeder, E.3
Pahnke, J.4
Kroemer, H.K.5
Siegmund, W.6
Kunert-Keil, C.7
Walker, L.C.8
Warzok, R.W.9
-
56
-
-
2942723107
-
The role of P-glycoprotein in cerebral amyloid angiopathy; Implications for the early pathogenesis of Alzheimers disease
-
Vogelgesang, S., Warzok, R. W., Cascorbi, I., Kunert-Keil, C., Schroeder, E., Kroemer, H. K., Siegmund, W., Walker, L. C., and Pahnke, J. (2004) The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimers disease Curr. Alzheimer Res. 1, 121-125
-
(2004)
Curr. Alzheimer Res.
, vol.1
, pp. 121-125
-
-
Vogelgesang, S.1
Warzok, R.W.2
Cascorbi, I.3
Kunert-Keil, C.4
Schroeder, E.5
Kroemer, H.K.6
Siegmund, W.7
Walker, L.C.8
Pahnke, J.9
-
57
-
-
77957963537
-
Amyloid efflux transporter expression at the blood-brain barrier declines in normal aging
-
Silverberg, G. D., Messier, A. A., Miller, M. C., Machan, J. T., Majmudar, S. S., Stopa, E. G., Donahue, J. E., and Johanson, C. E. (2010) Amyloid efflux transporter expression at the blood-brain barrier declines in normal aging J. Neuropathol. Exp. Neurol. 69, 1034-1043
-
(2010)
J. Neuropathol. Exp. Neurol.
, vol.69
, pp. 1034-1043
-
-
Silverberg, G.D.1
Messier, A.A.2
Miller, M.C.3
MacHan, J.T.4
Majmudar, S.S.5
Stopa, E.G.6
Donahue, J.E.7
Johanson, C.E.8
-
58
-
-
80052672466
-
Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice
-
Brenn, A., Grube, M., Peters, M., Fischer, A., Jedlitschky, G., Kroemer, H. K., Warzok, R. W., and Vogelgesang, S. (2011) Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice Int. J. Alzheimer's Dis. 2011, 690121
-
(2011)
Int. J. Alzheimer's Dis.
, vol.2011
, pp. 690121
-
-
Brenn, A.1
Grube, M.2
Peters, M.3
Fischer, A.4
Jedlitschky, G.5
Kroemer, H.K.6
Warzok, R.W.7
Vogelgesang, S.8
-
59
-
-
77957352509
-
ABC efflux transporters in brain vasculature of Alzheimers subjects
-
Wijesuriya, H. C., Bullock, J. Y., Faull, R. L., Hladky, S. B., and Barrand, M. A. (2010) ABC efflux transporters in brain vasculature of Alzheimers subjects Brain Res. 1358, 228-238
-
(2010)
Brain Res.
, vol.1358
, pp. 228-238
-
-
Wijesuriya, H.C.1
Bullock, J.Y.2
Faull, R.L.3
Hladky, S.B.4
Barrand, M.A.5
-
60
-
-
40849102300
-
LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-beta peptide in a blood-brain barrier in vitro model
-
Nazer, B., Hong, S., and Selkoe, D. J. (2008) LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-beta peptide in a blood-brain barrier in vitro model Neurobiol. Dis. 30, 94-102
-
(2008)
Neurobiol. Dis.
, vol.30
, pp. 94-102
-
-
Nazer, B.1
Hong, S.2
Selkoe, D.J.3
-
61
-
-
33750017850
-
Functional characterization of the brain-to-blood efflux clearance of human amyloid-beta peptide (1-40) across the rat blood-brain barrier
-
Ito, S., Ohtsuki, S., and Terasaki, T. (2006) Functional characterization of the brain-to-blood efflux clearance of human amyloid-beta peptide (1-40) across the rat blood-brain barrier Neurosci. Res. 56, 246-252
-
(2006)
Neurosci. Res.
, vol.56
, pp. 246-252
-
-
Ito, S.1
Ohtsuki, S.2
Terasaki, T.3
-
62
-
-
67349212434
-
P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-beta
-
Tai, L. M., Loughlin, A. J., Male, D. K., and Romero, I. A. (2009) P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-beta J. Cereb. Blood Flow Metab. 29, 1079-1083
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 1079-1083
-
-
Tai, L.M.1
Loughlin, A.J.2
Male, D.K.3
Romero, I.A.4
-
63
-
-
78650659385
-
Apical-to-basolateral transport of amyloid-beta peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by P-glycoprotein
-
Candela, P., Gosselet, F., Saint-Pol, J., Sevin, E., Boucau, M. C., Boulanger, E., Cecchelli, R., and Fenart, L. (2010) Apical-to-basolateral transport of amyloid-beta peptides through blood-brain barrier cells is mediated by the receptor for advanced glycation end-products and is restricted by P-glycoprotein J. Alzheimer's Dis. 22, 849-859
-
(2010)
J. Alzheimer's Dis.
, vol.22
, pp. 849-859
-
-
Candela, P.1
Gosselet, F.2
Saint-Pol, J.3
Sevin, E.4
Boucau, M.C.5
Boulanger, E.6
Cecchelli, R.7
Fenart, L.8
-
64
-
-
0036644903
-
Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918
-
Kruijtzer, C. M., Beijnen, J. H., Rosing, H., ten Bokkel Huinink, W. W., Schot, M., Jewell, R. C., Paul, E. M., and Schellens, J. H. (2002) Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918 J. Clin. Oncol. 20, 2943-2950
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 2943-2950
-
-
Kruijtzer, C.M.1
Beijnen, J.H.2
Rosing, H.3
Ten Bokkel Huinink, W.W.4
Schot, M.5
Jewell, R.C.6
Paul, E.M.7
Schellens, J.H.8
-
65
-
-
85007163375
-
Enhanced Brain Amyloid-beta Clearance by Rifampicin and Caffeine as a Possible Protective Mechanism against Alzheimers Disease
-
Qosa, H., Abuznait, A. H., Hill, R. A., and Kaddoumi, A. (2012) Enhanced Brain Amyloid-beta Clearance by Rifampicin and Caffeine as a Possible Protective Mechanism against Alzheimers Disease J. Alzheimers Dis. 30, 1-15
-
(2012)
J. Alzheimers Dis.
, vol.30
, pp. 1-15
-
-
Qosa, H.1
Abuznait, A.H.2
Hill, R.A.3
Kaddoumi, A.4
-
66
-
-
0013615899
-
RAGE and amyloid-beta peptide neurotoxicity in Alzheimers disease
-
Yan, S. D., Chen, X., Fu, J., Chen, M., Zhu, H., Roher, A., Slattery, T., Zhao, L., Nagashima, M., Morser, J., Migheli, A., Nawroth, P., Stern, D., and Schmidt, A. M. (1996) RAGE and amyloid-beta peptide neurotoxicity in Alzheimers disease Nature 382, 685-691
-
(1996)
Nature
, vol.382
, pp. 685-691
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
Chen, M.4
Zhu, H.5
Roher, A.6
Slattery, T.7
Zhao, L.8
Nagashima, M.9
Morser, J.10
Migheli, A.11
Nawroth, P.12
Stern, D.13
Schmidt, A.M.14
-
67
-
-
4944230477
-
Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier
-
Bauer, B., Hartz, A. M., Fricker, G., and Miller, D. S. (2004) Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier Mol. Pharmacol. 66, 413-419
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 413-419
-
-
Bauer, B.1
Hartz, A.M.2
Fricker, G.3
Miller, D.S.4
-
68
-
-
77951078680
-
Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimers disease
-
Hartz, A. M., Miller, D. S., and Bauer, B. (2010) Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimers disease Mol. Pharmacol. 77, 715-723
-
(2010)
Mol. Pharmacol.
, vol.77
, pp. 715-723
-
-
Hartz, A.M.1
Miller, D.S.2
Bauer, B.3
-
69
-
-
77953258151
-
The role of ATP-binding cassette transporter A1 in Alzheimers disease and neurodegeneration
-
Koldamova, R., Fitz, N. F., and Lefterov, I. (2010) The role of ATP-binding cassette transporter A1 in Alzheimers disease and neurodegeneration Biochim. Biophys. Acta 1801, 824-830
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 824-830
-
-
Koldamova, R.1
Fitz, N.F.2
Lefterov, I.3
-
70
-
-
14844319827
-
MRNA expression of the ATP-binding cassette transporter subfamily A (ABCA) in rat and human brain capillary endothelial cells
-
Ohtsuki, S., Watanabe, Y., Hori, S., Suzuki, H., Bhongsatiern, J., Fujiyoshi, M., Kamoi, M., Kamiya, N., Takanaga, H., and Terasaki, T. (2004) mRNA expression of the ATP-binding cassette transporter subfamily A (ABCA) in rat and human brain capillary endothelial cells Biol. Pharm. Bull. 27, 1437-1440
-
(2004)
Biol. Pharm. Bull.
, vol.27
, pp. 1437-1440
-
-
Ohtsuki, S.1
Watanabe, Y.2
Hori, S.3
Suzuki, H.4
Bhongsatiern, J.5
Fujiyoshi, M.6
Kamoi, M.7
Kamiya, N.8
Takanaga, H.9
Terasaki, T.10
-
71
-
-
76449103011
-
Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus
-
Akram, A., Schmeidler, J., Katsel, P., Hof, P. R., and Haroutunian, V. (2010) Increased expression of cholesterol transporter ABCA1 is highly correlated with severity of dementia in AD hippocampus Brain Res. 1318, 167-177
-
(2010)
Brain Res.
, vol.1318
, pp. 167-177
-
-
Akram, A.1
Schmeidler, J.2
Katsel, P.3
Hof, P.R.4
Haroutunian, V.5
-
72
-
-
40949149021
-
ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-beta peptide (1-40) at the blood-brain barrier
-
Akanuma, S., Ohtsuki, S., Doi, Y., Tachikawa, M., Ito, S., Hori, S., Asashima, T., Hashimoto, T., Yamada, K., Ueda, K., Iwatsubo, T., and Terasaki, T. (2008) ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-beta peptide (1-40) at the blood-brain barrier Neurochem. Int. 52, 956-961
-
(2008)
Neurochem. Int.
, vol.52
, pp. 956-961
-
-
Akanuma, S.1
Ohtsuki, S.2
Doi, Y.3
Tachikawa, M.4
Ito, S.5
Hori, S.6
Asashima, T.7
Hashimoto, T.8
Yamada, K.9
Ueda, K.10
Iwatsubo, T.11
Terasaki, T.12
-
73
-
-
84862878635
-
Brain Pericytes ABCA1 Expression Mediates Cholesterol Efflux but not Cellular Amyloid-beta Peptide Accumulation
-
Saint-Pol, J., Vandenhaute, E., Boucau, M. C., Candela, P., Dehouck, L., Cecchelli, R., Dehouck, M. P., Fenart, L., and Gosselet, F. (2012) Brain Pericytes ABCA1 Expression Mediates Cholesterol Efflux but not Cellular Amyloid-beta Peptide Accumulation J. Alzheimer's Dis. 30, 489-503
-
(2012)
J. Alzheimer's Dis.
, vol.30
, pp. 489-503
-
-
Saint-Pol, J.1
Vandenhaute, E.2
Boucau, M.C.3
Candela, P.4
Dehouck, L.5
Cecchelli, R.6
Dehouck, M.P.7
Fenart, L.8
Gosselet, F.9
-
74
-
-
69149109381
-
Greasing the wheels of Abeta clearance in Alzheimers disease: The role of lipids and apolipoprotein e
-
Fan, J., Donkin, J., and Wellington, C. (2009) Greasing the wheels of Abeta clearance in Alzheimers disease: the role of lipids and apolipoprotein E Biofactors 35, 239-248
-
(2009)
Biofactors
, vol.35
, pp. 239-248
-
-
Fan, J.1
Donkin, J.2
Wellington, C.3
-
75
-
-
33750576450
-
Apolipoprotein-E modulates the cytotoxic effect of beta-amyloid on rat brain endothelium in an isoform-dependent specific manner
-
Folin, M., Baiguera, S., Guidolin, D., Di Liddo, R., Grandi, C., De Carlo, E., Nussdorfer, G. G., and Parnigotto, P. P. (2006) Apolipoprotein-E modulates the cytotoxic effect of beta-amyloid on rat brain endothelium in an isoform-dependent specific manner Int. J. Mol. Med. 17, 821-826
-
(2006)
Int. J. Mol. Med.
, vol.17
, pp. 821-826
-
-
Folin, M.1
Baiguera, S.2
Guidolin, D.3
Di Liddo, R.4
Grandi, C.5
De Carlo, E.6
Nussdorfer, G.G.7
Parnigotto, P.P.8
-
76
-
-
84863504256
-
Apolipoprotein e and apolipoprotein e receptors: Normal biology and roles in Alzheimer disease
-
Holtzman, D. M., Herz, J., and Bu, G. (2012) Apolipoprotein e and apolipoprotein e receptors: normal biology and roles in Alzheimer disease Cold Spring Harbor Perspect. Med. 2, a006312
-
(2012)
Cold Spring Harbor Perspect. Med.
, vol.2
, pp. 006312
-
-
Holtzman, D.M.1
Herz, J.2
Bu, G.3
-
78
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimers disease in late onset families
-
Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., and Pericak-Vance, M. A. (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimers disease in late onset families Science 261, 921-923
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
79
-
-
57449084208
-
ApoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain
-
Deane, R., Sagare, A., Hamm, K., Parisi, M., Lane, S., Finn, M. B., Holtzman, D. M., and Zlokovic, B. V. (2008) apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain J. Clin. Invest. 118, 4002-4013
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 4002-4013
-
-
Deane, R.1
Sagare, A.2
Hamm, K.3
Parisi, M.4
Lane, S.5
Finn, M.B.6
Holtzman, D.M.7
Zlokovic, B.V.8
-
80
-
-
79959772357
-
Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance
-
Castellano, J. M., Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., Goate, A. M., Bales, K. R., Paul, S. M., Bateman, R. J., and Holtzman, D. M. (2011) Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance Sci. Transl. Med. 3, 89ra57
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Castellano, J.M.1
Kim, J.2
Stewart, F.R.3
Jiang, H.4
Demattos, R.B.5
Patterson, B.W.6
Fagan, A.M.7
Morris, J.C.8
Mawuenyega, K.G.9
Cruchaga, C.10
Goate, A.M.11
Bales, K.R.12
Paul, S.M.13
Bateman, R.J.14
Holtzman, D.M.15
-
81
-
-
38849086036
-
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease
-
Wahrle, S. E., Jiang, H., Parsadanian, M., Kim, J., Li, A., Knoten, A., Jain, S., Hirsch-Reinshagen, V., Wellington, C. L., Bales, K. R., Paul, S. M., and Holtzman, D. M. (2008) Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease J. Clin. Invest. 118, 671-682
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 671-682
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Kim, J.4
Li, A.5
Knoten, A.6
Jain, S.7
Hirsch-Reinshagen, V.8
Wellington, C.L.9
Bales, K.R.10
Paul, S.M.11
Holtzman, D.M.12
-
82
-
-
0034214329
-
Lipidation of apolipoprotein e influences its isoform-specific interaction with Alzheimers amyloid beta peptides
-
Tokuda, T., Calero, M., Matsubara, E., Vidal, R., Kumar, A., Permanne, B., Zlokovic, B., Smith, J. D., Ladu, M. J., Rostagno, A., Frangione, B., and Ghiso, J. (2000) Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimers amyloid beta peptides Biochem. J. 348 (Pt 2) 359-365
-
(2000)
Biochem. J.
, vol.348
, Issue.PART 2
, pp. 359-365
-
-
Tokuda, T.1
Calero, M.2
Matsubara, E.3
Vidal, R.4
Kumar, A.5
Permanne, B.6
Zlokovic, B.7
Smith, J.D.8
Ladu, M.J.9
Rostagno, A.10
Frangione, B.11
Ghiso, J.12
-
83
-
-
4243215848
-
Apolipoprotein e isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimers disease
-
Holtzman, D. M., Bales, K. R., Tenkova, T., Fagan, A. M., Parsadanian, M., Sartorius, L. J., Mackey, B., Olney, J., McKeel, D., Wozniak, D., and Paul, S. M. (2000) Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimers disease Proc. Natl. Acad. Sci. U.S.A. 97, 2892-2897
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 2892-2897
-
-
Holtzman, D.M.1
Bales, K.R.2
Tenkova, T.3
Fagan, A.M.4
Parsadanian, M.5
Sartorius, L.J.6
MacKey, B.7
Olney, J.8
McKeel, D.9
Wozniak, D.10
Paul, S.M.11
-
84
-
-
0034796318
-
Human apolipoprotein E4 accelerates beta-amyloid deposition in APPsw transgenic mouse brain
-
Carter, D. B., Dunn, E., McKinley, D. D., Stratman, N. C., Boyle, T. P., Kuiper, S. L., Oostveen, J. A., Weaver, R. J., Boller, J. A., and Gurney, M. E. (2001) Human apolipoprotein E4 accelerates beta-amyloid deposition in APPsw transgenic mouse brain Ann. Neurol. 50, 468-475
-
(2001)
Ann. Neurol.
, vol.50
, pp. 468-475
-
-
Carter, D.B.1
Dunn, E.2
McKinley, D.D.3
Stratman, N.C.4
Boyle, T.P.5
Kuiper, S.L.6
Oostveen, J.A.7
Weaver, R.J.8
Boller, J.A.9
Gurney, M.E.10
-
85
-
-
84863016392
-
Up-regulation of ATP binding cassette transporter A1 expression by very low density lipoprotein receptor and apolipoprotein e receptor 2
-
Chen, X., Guo, Z., Okoro, E. U., Zhang, H., Zhou, L., Lin, X., Rollins, A. T., and Yang, H. (2012) Up-regulation of ATP binding cassette transporter A1 expression by very low density lipoprotein receptor and apolipoprotein E receptor 2 J. Biol. Chem. 287, 3751-3759
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 3751-3759
-
-
Chen, X.1
Guo, Z.2
Okoro, E.U.3
Zhang, H.4
Zhou, L.5
Lin, X.6
Rollins, A.T.7
Yang, H.8
-
86
-
-
84861637607
-
Apolipoprotein-E controls adenosine triphosphate-binding cassette transporters ABCB1 and ABCC1 on cerebral microvessels after methamphetamine intoxication
-
ElAli, A., Urrutia, A., Rubio-Araiz, A., Hernandez-Jimenez, M., Colado, M. I., Doeppner, T. R., and Hermann, D. M. (2012) Apolipoprotein-E controls adenosine triphosphate-binding cassette transporters ABCB1 and ABCC1 on cerebral microvessels after methamphetamine intoxication Stroke 43, 1647-1653
-
(2012)
Stroke
, vol.43
, pp. 1647-1653
-
-
Elali, A.1
Urrutia, A.2
Rubio-Araiz, A.3
Hernandez-Jimenez, M.4
Colado, M.I.5
Doeppner, T.R.6
Hermann, D.M.7
-
87
-
-
4644361588
-
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE
-
Wahrle, S. E., Jiang, H., Parsadanian, M., Legleiter, J., Han, X., Fryer, J. D., Kowalewski, T., and Holtzman, D. M. (2004) ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE J. Biol. Chem. 279, 40987-40993
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40987-40993
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Legleiter, J.4
Han, X.5
Fryer, J.D.6
Kowalewski, T.7
Holtzman, D.M.8
-
88
-
-
30044442937
-
Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease
-
Wahrle, S. E., Jiang, H., Parsadanian, M., Hartman, R. E., Bales, K. R., Paul, S. M., and Holtzman, D. M. (2005) Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease J. Biol. Chem. 280, 43236-43242
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 43236-43242
-
-
Wahrle, S.E.1
Jiang, H.2
Parsadanian, M.3
Hartman, R.E.4
Bales, K.R.5
Paul, S.M.6
Holtzman, D.M.7
-
89
-
-
30044441879
-
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease
-
Hirsch-Reinshagen, V., Maia, L. F., Burgess, B. L., Blain, J. F., Naus, K. E., McIsaac, S. A., Parkinson, P. F., Chan, J. Y., Tansley, G. H., Hayden, M. R., Poirier, J., Van Nostrand, W., and Wellington, C. L. (2005) The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease J. Biol. Chem. 280, 43243-43256
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 43243-43256
-
-
Hirsch-Reinshagen, V.1
Maia, L.F.2
Burgess, B.L.3
Blain, J.F.4
Naus, K.E.5
McIsaac, S.A.6
Parkinson, P.F.7
Chan, J.Y.8
Tansley, G.H.9
Hayden, M.R.10
Poirier, J.11
Van Nostrand, W.12
Wellington, C.L.13
-
90
-
-
30044438463
-
Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice
-
Koldamova, R., Staufenbiel, M., and Lefterov, I. (2005) Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice J. Biol. Chem. 280, 43224-43235
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 43224-43235
-
-
Koldamova, R.1
Staufenbiel, M.2
Lefterov, I.3
-
91
-
-
0037969631
-
22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion
-
Koldamova, R. P., Lefterov, I. M., Ikonomovic, M. D., Skoko, J., Lefterov, P. I., Isanski, B. A., DeKosky, S. T., and Lazo, J. S. (2003) 22R-hydroxycholesterol and 9-cis-retinoic acid induce ATP-binding cassette transporter A1 expression and cholesterol efflux in brain cells and decrease amyloid beta secretion J. Biol. Chem. 278, 13244-13256
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13244-13256
-
-
Koldamova, R.P.1
Lefterov, I.M.2
Ikonomovic, M.D.3
Skoko, J.4
Lefterov, P.I.5
Isanski, B.A.6
Dekosky, S.T.7
Lazo, J.S.8
-
92
-
-
34047250984
-
Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein e discs and suppression of amyloid-beta peptide generation
-
Kim, W. S., Rahmanto, A. S., Kamili, A., Rye, K. A., Guillemin, G. J., Gelissen, I. C., Jessup, W., Hill, A. F., and Garner, B. (2007) Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation J. Biol. Chem. 282, 2851-2861
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2851-2861
-
-
Kim, W.S.1
Rahmanto, A.S.2
Kamili, A.3
Rye, K.A.4
Guillemin, G.J.5
Gelissen, I.C.6
Jessup, W.7
Hill, A.F.8
Garner, B.9
-
93
-
-
44649197748
-
ApoE promotes the proteolytic degradation of Abeta
-
Jiang, Q., Lee, C. Y., Mandrekar, S., Wilkinson, B., Cramer, P., Zelcer, N., Mann, K., Lamb, B., Willson, T. M., Collins, J. L., Richardson, J. C., Smith, J. D., Comery, T. A., Riddell, D., Holtzman, D. M., Tontonoz, P., and Landreth, G. E. (2008) ApoE promotes the proteolytic degradation of Abeta Neuron 58, 681-693
-
(2008)
Neuron
, vol.58
, pp. 681-693
-
-
Jiang, Q.1
Lee, C.Y.2
Mandrekar, S.3
Wilkinson, B.4
Cramer, P.5
Zelcer, N.6
Mann, K.7
Lamb, B.8
Willson, T.M.9
Collins, J.L.10
Richardson, J.C.11
Smith, J.D.12
Comery, T.A.13
Riddell, D.14
Holtzman, D.M.15
Tontonoz, P.16
Landreth, G.E.17
-
94
-
-
0042346382
-
Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion
-
Sun, Y., Yao, J., Kim, T. W., and Tall, A. R. (2003) Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion J. Biol. Chem. 278, 27688-27694
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27688-27694
-
-
Sun, Y.1
Yao, J.2
Kim, T.W.3
Tall, A.R.4
-
95
-
-
0032568552
-
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons
-
Simons, M., Keller, P., De Strooper, B., Beyreuther, K., Dotti, C. G., and Simons, K. (1998) Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons Proc. Natl. Acad. Sci. U.S.A. 95, 6460-6464
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
96
-
-
0345669752
-
Alzheimers disease: The cholesterol connection
-
Puglielli, L., Tanzi, R. E., and Kovacs, D. M. (2003) Alzheimers disease: the cholesterol connection Nat. Neurosci. 6, 345-351
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 345-351
-
-
Puglielli, L.1
Tanzi, R.E.2
Kovacs, D.M.3
-
97
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10
-
Kojro, E., Gimpl, G., Lammich, S., Marz, W., and Fahrenholz, F. (2001) Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10 Proc. Natl. Acad. Sci. U.S.A. 98, 5815-5820
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 5815-5820
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
Marz, W.4
Fahrenholz, F.5
-
98
-
-
0033776534
-
ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine
-
Hamon, Y., Broccardo, C., Chambenoit, O., Luciani, M. F., Toti, F., Chaslin, S., Freyssinet, J. M., Devaux, P. F., McNeish, J., Marguet, D., and Chimini, G. (2000) ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine Nat. Cell Biol. 2, 399-406
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 399-406
-
-
Hamon, Y.1
Broccardo, C.2
Chambenoit, O.3
Luciani, M.F.4
Toti, F.5
Chaslin, S.6
Freyssinet, J.M.7
Devaux, P.F.8
McNeish, J.9
Marguet, D.10
Chimini, G.11
-
99
-
-
0034693064
-
Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1
-
Wang, N., Silver, D. L., Costet, P., and Tall, A. R. (2000) Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1 J. Biol. Chem. 275, 33053-33058
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33053-33058
-
-
Wang, N.1
Silver, D.L.2
Costet, P.3
Tall, A.R.4
-
100
-
-
0037108819
-
Liver X receptors in the central nervous system: From lipid homeostasis to neuronal degeneration
-
Wang, L., Schuster, G. U., Hultenby, K., Zhang, Q., Andersson, S., and Gustafsson, J. A. (2002) Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration Proc. Natl. Acad. Sci. U.S.A. 99, 13878-13883
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 13878-13883
-
-
Wang, L.1
Schuster, G.U.2
Hultenby, K.3
Zhang, Q.4
Andersson, S.5
Gustafsson, J.A.6
-
101
-
-
85047684678
-
Regulation of cholesterol homeostasis by the liver X receptors in the central nervous system
-
Whitney, K. D., Watson, M. A., Collins, J. L., Benson, W. G., Stone, T. M., Numerick, M. J., Tippin, T. K., Wilson, J. G., Winegar, D. A., and Kliewer, S. A. (2002) Regulation of cholesterol homeostasis by the liver X receptors in the central nervous system Mol. Endocrinol. 16, 1378-1385
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 1378-1385
-
-
Whitney, K.D.1
Watson, M.A.2
Collins, J.L.3
Benson, W.G.4
Stone, T.M.5
Numerick, M.J.6
Tippin, T.K.7
Wilson, J.G.8
Winegar, D.A.9
Kliewer, S.A.10
-
102
-
-
14244255485
-
The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimers disease
-
Koldamova, R. P., Lefterov, I. M., Staufenbiel, M., Wolfe, D., Huang, S., Glorioso, J. C., Walter, M., Roth, M. G., and Lazo, J. S. (2005) The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimers disease J. Biol. Chem. 280, 4079-4088
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4079-4088
-
-
Koldamova, R.P.1
Lefterov, I.M.2
Staufenbiel, M.3
Wolfe, D.4
Huang, S.5
Glorioso, J.C.6
Walter, M.7
Roth, M.G.8
Lazo, J.S.9
-
103
-
-
33947610707
-
The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimers disease
-
Riddell, D. R., Zhou, H., Comery, T. A., Kouranova, E., Lo, C. F., Warwick, H. K., Ring, R. H., Kirksey, Y., Aschmies, S., Xu, J., Kubek, K., Hirst, W. D., Gonzales, C., Chen, Y., Murphy, E., Leonard, S., Vasylyev, D., Oganesian, A., Martone, R. L., Pangalos, M. N., Reinhart, P. H., and Jacobsen, J. S. (2007) The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimers disease Mol. Cell. Neurosci. 34, 621-628
-
(2007)
Mol. Cell. Neurosci.
, vol.34
, pp. 621-628
-
-
Riddell, D.R.1
Zhou, H.2
Comery, T.A.3
Kouranova, E.4
Lo, C.F.5
Warwick, H.K.6
Ring, R.H.7
Kirksey, Y.8
Aschmies, S.9
Xu, J.10
Kubek, K.11
Hirst, W.D.12
Gonzales, C.13
Chen, Y.14
Murphy, E.15
Leonard, S.16
Vasylyev, D.17
Oganesian, A.18
Martone, R.L.19
Pangalos, M.N.20
Reinhart, P.H.21
Jacobsen, J.S.22
more..
-
104
-
-
79958773215
-
Liver X receptor activation restores memory in aged AD mice without reducing amyloid
-
Vanmierlo, T., Rutten, K., Dederen, J., Bloks, V. W., van Vark-van der Zee, L. C., Kuipers, F., Kiliaan, A., Blokland, A., Sijbrands, E. J., Steinbusch, H., Prickaerts, J., Lutjohann, D., and Mulder, M. (2011) Liver X receptor activation restores memory in aged AD mice without reducing amyloid Neurobiol. Aging 32, 1262-1272
-
(2011)
Neurobiol. Aging
, vol.32
, pp. 1262-1272
-
-
Vanmierlo, T.1
Rutten, K.2
Dederen, J.3
Bloks, V.W.4
Van Vark-Van Der Zee, L.C.5
Kuipers, F.6
Kiliaan, A.7
Blokland, A.8
Sijbrands, E.J.9
Steinbusch, H.10
Prickaerts, J.11
Lutjohann, D.12
Mulder, M.13
-
105
-
-
79956311751
-
Critical role of astroglial apolipoprotein e and liver X receptor-alpha expression for microglial Abeta phagocytosis
-
Terwel, D., Steffensen, K. R., Verghese, P. B., Kummer, M. P., Gustafsson, J. A., Holtzman, D. M., and Heneka, M. T. (2011) Critical role of astroglial apolipoprotein E and liver X receptor-alpha expression for microglial Abeta phagocytosis J. Neurosci. 31, 7049-7059
-
(2011)
J. Neurosci.
, vol.31
, pp. 7049-7059
-
-
Terwel, D.1
Steffensen, K.R.2
Verghese, P.B.3
Kummer, M.P.4
Gustafsson, J.A.5
Holtzman, D.M.6
Heneka, M.T.7
-
106
-
-
0037073670
-
Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels
-
Fukumoto, H., Deng, A., Irizarry, M. C., Fitzgerald, M. L., and Rebeck, G. W. (2002) Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels J. Biol. Chem. 277, 48508-48513
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48508-48513
-
-
Fukumoto, H.1
Deng, A.2
Irizarry, M.C.3
Fitzgerald, M.L.4
Rebeck, G.W.5
-
107
-
-
84860377430
-
MiR-106b impairs cholesterol efflux and increases Abeta levels by repressing ABCA1 expression
-
Kim, J., Yoon, H., Ramirez, C. M., Lee, S. M., Hoe, H. S., and Fernandez-Hernando, C. (2012) miR-106b impairs cholesterol efflux and increases Abeta levels by repressing ABCA1 expression Exp. Neurol. 235, 476-483
-
(2012)
Exp. Neurol.
, vol.235
, pp. 476-483
-
-
Kim, J.1
Yoon, H.2
Ramirez, C.M.3
Lee, S.M.4
Hoe, H.S.5
Fernandez-Hernando, C.6
-
108
-
-
77953285846
-
Increased ATP-binding cassette transporter A1 expression in Alzheimers disease hippocampal neurons
-
Kim, W. S., Bhatia, S., Elliott, D. A., Agholme, L., Kagedal, K., McCann, H., Halliday, G. M., Barnham, K. J., and Garner, B. (2010) Increased ATP-binding cassette transporter A1 expression in Alzheimers disease hippocampal neurons J. Alzheimer's Dis. 21, 193-205
-
(2010)
J. Alzheimer's Dis.
, vol.21
, pp. 193-205
-
-
Kim, W.S.1
Bhatia, S.2
Elliott, D.A.3
Agholme, L.4
Kagedal, K.5
McCann, H.6
Halliday, G.M.7
Barnham, K.J.8
Garner, B.9
-
109
-
-
34147169863
-
Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid-beta peptide levels in vivo
-
Hirsch-Reinshagen, V., Chan, J. Y., Wilkinson, A., Tanaka, T., Fan, J., Ou, G., Maia, L. F., Singaraja, R. R., Hayden, M. R., and Wellington, C. L. (2007) Physiologically regulated transgenic ABCA1 does not reduce amyloid burden or amyloid-beta peptide levels in vivo J. Lipid Res. 48, 914-923
-
(2007)
J. Lipid Res.
, vol.48
, pp. 914-923
-
-
Hirsch-Reinshagen, V.1
Chan, J.Y.2
Wilkinson, A.3
Tanaka, T.4
Fan, J.5
Ou, G.6
Maia, L.F.7
Singaraja, R.R.8
Hayden, M.R.9
Wellington, C.L.10
-
110
-
-
0034665001
-
Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2
-
Zhao, L. X., Zhou, C. J., Tanaka, A., Nakata, M., Hirabayashi, T., Amachi, T., Shioda, S., Ueda, K., and Inagaki, N. (2000) Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2 Biochem. J. 350 (Pt 3) 865-872
-
(2000)
Biochem. J.
, vol.350
, Issue.PART 3
, pp. 865-872
-
-
Zhao, L.X.1
Zhou, C.J.2
Tanaka, A.3
Nakata, M.4
Hirabayashi, T.5
Amachi, T.6
Shioda, S.7
Ueda, K.8
Inagaki, N.9
-
111
-
-
33645296057
-
ABCA2 is a marker of neural progenitors and neuronal subsets in the adult rodent brain
-
Broccardo, C., Nieoullon, V., Amin, R., Masmejean, F., Carta, S., Tassi, S., Pophillat, M., Rubartelli, A., Pierres, M., Rougon, G., Nieoullon, A., Chazal, G., and Chimini, G. (2006) ABCA2 is a marker of neural progenitors and neuronal subsets in the adult rodent brain J. Neurochem. 97, 345-355
-
(2006)
J. Neurochem.
, vol.97
, pp. 345-355
-
-
Broccardo, C.1
Nieoullon, V.2
Amin, R.3
Masmejean, F.4
Carta, S.5
Tassi, S.6
Pophillat, M.7
Rubartelli, A.8
Pierres, M.9
Rougon, G.10
Nieoullon, A.11
Chazal, G.12
Chimini, G.13
-
112
-
-
33846028781
-
The ABCA2 transporter: Intracellular roles in trafficking and metabolism of LDL-derived cholesterol and sterol-related compounds
-
Mack, J. T., Townsend, D. M., Beljanski, V., and Tew, K. D. (2007) The ABCA2 transporter: intracellular roles in trafficking and metabolism of LDL-derived cholesterol and sterol-related compounds Curr. Drug Metab. 8, 47-57
-
(2007)
Curr. Drug Metab.
, vol.8
, pp. 47-57
-
-
MacK, J.T.1
Townsend, D.M.2
Beljanski, V.3
Tew, K.D.4
-
113
-
-
7944226987
-
Association of ABCA2 expression with determinants of Alzheimers disease
-
Chen, Z. J., Vulevic, B., Ile, K. E., Soulika, A., Davis, W., Jr., Reiner, P. B., Connop, B. P., Nathwani, P., Trojanowski, J. Q., and Tew, K. D. (2004) Association of ABCA2 expression with determinants of Alzheimers disease FASEB J. 18, 1129-1131
-
(2004)
FASEB J.
, vol.18
, pp. 1129-1131
-
-
Chen, Z.J.1
Vulevic, B.2
Ile, K.E.3
Soulika, A.4
Davis Jr., W.5
Reiner, P.B.6
Connop, B.P.7
Nathwani, P.8
Trojanowski, J.Q.9
Tew, K.D.10
-
114
-
-
81755172001
-
The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells
-
Davis, W., Jr. (2011) The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells Biochim. Biophys. Acta 1811, 1152-1164
-
(2011)
Biochim. Biophys. Acta
, vol.1811
, pp. 1152-1164
-
-
Davis Jr., W.1
-
115
-
-
3042563663
-
Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells
-
Davis, W., Jr., Boyd, J. T., Ile, K. E., and Tew, K. D. (2004) Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells Biochim. Biophys. Acta 1683, 89-100
-
(2004)
Biochim. Biophys. Acta
, vol.1683
, pp. 89-100
-
-
Davis Jr., W.1
Boyd, J.T.2
Ile, K.E.3
Tew, K.D.4
-
116
-
-
0042733013
-
Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production
-
Grbovic, O. M., Mathews, P. M., Jiang, Y., Schmidt, S. D., Dinakar, R., Summers-Terio, N. B., Ceresa, B. P., Nixon, R. A., and Cataldo, A. M. (2003) Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production J. Biol. Chem. 278, 31261-31268
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31261-31268
-
-
Grbovic, O.M.1
Mathews, P.M.2
Jiang, Y.3
Schmidt, S.D.4
Dinakar, R.5
Summers-Terio, N.B.6
Ceresa, B.P.7
Nixon, R.A.8
Cataldo, A.M.9
-
117
-
-
19944429282
-
ABCA2 is a strong genetic risk factor for early-onset Alzheimers disease
-
Mace, S., Cousin, E., Ricard, S., Genin, E., Spanakis, E., Lafargue-Soubigou, C., Genin, B., Fournel, R., Roche, S., Haussy, G., Massey, F., Soubigou, S., Brefort, G., Benoit, P., Brice, A., Campion, D., Hollis, M., Pradier, L., Benavides, J., and Deleuze, J. F. (2005) ABCA2 is a strong genetic risk factor for early-onset Alzheimers disease Neurobiol. Dis. 18, 119-125
-
(2005)
Neurobiol. Dis.
, vol.18
, pp. 119-125
-
-
MacE, S.1
Cousin, E.2
Ricard, S.3
Genin, E.4
Spanakis, E.5
Lafargue-Soubigou, C.6
Genin, B.7
Fournel, R.8
Roche, S.9
Haussy, G.10
Massey, F.11
Soubigou, S.12
Brefort, G.13
Benoit, P.14
Brice, A.15
Campion, D.16
Hollis, M.17
Pradier, L.18
Benavides, J.19
Deleuze, J.F.20
more..
-
118
-
-
33745804992
-
Ethnicity-dependent genetic association of ABCA2 with sporadic Alzheimers disease
-
Wollmer, M. A., Kapaki, E., Hersberger, M., Muntwyler, J., Brunner, F., Tsolaki, M., Akatsu, H., Kosaka, K., Michikawa, M., Molyva, D., Paraskevas, G. P., Lutjohann, D., von Eckardstein, A., Hock, C., Nitsch, R. M., and Papassotiropoulos, A. (2006) Ethnicity-dependent genetic association of ABCA2 with sporadic Alzheimers disease Am. J. Med. Genet., Part B 141B, 534-536
-
(2006)
Am. J. Med. Genet., Part B
, vol.141
, pp. 534-536
-
-
Wollmer, M.A.1
Kapaki, E.2
Hersberger, M.3
Muntwyler, J.4
Brunner, F.5
Tsolaki, M.6
Akatsu, H.7
Kosaka, K.8
Michikawa, M.9
Molyva, D.10
Paraskevas, G.P.11
Lutjohann, D.12
Von Eckardstein, A.13
Hock, C.14
Nitsch, R.M.15
Papassotiropoulos, A.16
-
119
-
-
79958857741
-
The ATP-binding cassette transporter-2 (ABCA2) increases endogenous amyloid precursor protein expression and Abeta fragment generation
-
Davis, W., Jr. (2010) The ATP-binding cassette transporter-2 (ABCA2) increases endogenous amyloid precursor protein expression and Abeta fragment generation Curr. Alzheimer Res. 7, 566-577
-
(2010)
Curr. Alzheimer Res.
, vol.7
, pp. 566-577
-
-
Davis Jr., W.1
-
120
-
-
84855486329
-
Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin maturation and intracellular localization
-
Michaki, V., Guix, F. X., Vennekens, K., Munck, S., Dingwall, C., Davis, J. B., Townsend, D. M., Tew, K. D., Feiguin, F., De Strooper, B., Dotti, C. G., and Wahle, T. (2012) Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin maturation and intracellular localization J. Biol. Chem. 287, 1100-1111
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 1100-1111
-
-
Michaki, V.1
Guix, F.X.2
Vennekens, K.3
Munck, S.4
Dingwall, C.5
Davis, J.B.6
Townsend, D.M.7
Tew, K.D.8
Feiguin, F.9
De Strooper, B.10
Dotti, C.G.11
Wahle, T.12
-
121
-
-
0028885682
-
Amino-terminal deletions enhance aggregation of beta-amyloid peptides in vitro
-
Pike, C. J., Overman, M. J., and Cotman, C. W. (1995) Amino-terminal deletions enhance aggregation of beta-amyloid peptides in vitro J. Biol. Chem. 270, 23895-23898
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23895-23898
-
-
Pike, C.J.1
Overman, M.J.2
Cotman, C.W.3
-
122
-
-
20544436363
-
Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain
-
Aronica, E., Gorter, J. A., Redeker, S., van Vliet, E. A., Ramkema, M., Scheffer, G. L., Scheper, R. J., van der Valk, P., Leenstra, S., Baayen, J. C., Spliet, W. G., and Troost, D. (2005) Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain Epilepsia 46, 849-857
-
(2005)
Epilepsia
, vol.46
, pp. 849-857
-
-
Aronica, E.1
Gorter, J.A.2
Redeker, S.3
Van Vliet, E.A.4
Ramkema, M.5
Scheffer, G.L.6
Scheper, R.J.7
Van Der Valk, P.8
Leenstra, S.9
Baayen, J.C.10
Spliet, W.G.11
Troost, D.12
-
123
-
-
0035870289
-
Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues
-
Maliepaard, M., Scheffer, G. L., Faneyte, I. F., van Gastelen, M. A., Pijnenborg, A. C., Schinkel, A. H., van De Vijver, M. J., Scheper, R. J., and Schellens, J. H. (2001) Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues Cancer Res. 61, 3458-3464
-
(2001)
Cancer Res.
, vol.61
, pp. 3458-3464
-
-
Maliepaard, M.1
Scheffer, G.L.2
Faneyte, I.F.3
Van Gastelen, M.A.4
Pijnenborg, A.C.5
Schinkel, A.H.6
Van De Vijver, M.J.7
Scheper, R.J.8
Schellens, J.H.9
-
124
-
-
65649142529
-
ABCG2 is upregulated in Alzheimers brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides
-
Xiong, H., Callaghan, D., Jones, A., Bai, J., Rasquinha, I., Smith, C., Pei, K., Walker, D., Lue, L. F., Stanimirovic, D., and Zhang, W. (2009) ABCG2 is upregulated in Alzheimers brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides J. Neurosci. 29, 5463-5475
-
(2009)
J. Neurosci.
, vol.29
, pp. 5463-5475
-
-
Xiong, H.1
Callaghan, D.2
Jones, A.3
Bai, J.4
Rasquinha, I.5
Smith, C.6
Pei, K.7
Walker, D.8
Lue, L.F.9
Stanimirovic, D.10
Zhang, W.11
-
125
-
-
84861539923
-
ABCG2- and ABCG4-mediated efflux of amyloid-beta peptide 1-40 at the mouse blood-brain barrier
-
Do, T. M., Noel-Hudson, M. S., Ribes, S., Besengez, C., Smirnova, M., Cisternino, S., Buyse, M., Calon, F., Chimini, G., Chacun, H., Scherrmann, J. M., Farinotti, R., and Bourasset, F. (2012) ABCG2- and ABCG4-mediated efflux of amyloid-beta peptide 1-40 at the mouse blood-brain barrier J. Alzheimer's Dis. 30, 155-166
-
(2012)
J. Alzheimer's Dis.
, vol.30
, pp. 155-166
-
-
Do, T.M.1
Noel-Hudson, M.S.2
Ribes, S.3
Besengez, C.4
Smirnova, M.5
Cisternino, S.6
Buyse, M.7
Calon, F.8
Chimini, G.9
Chacun, H.10
Scherrmann, J.M.11
Farinotti, R.12
Bourasset, F.13
-
126
-
-
77956313661
-
ABCG2 reduces ROS-mediated toxicity and inflammation: A potential role in Alzheimers disease
-
Shen, S., Callaghan, D., Juzwik, C., Xiong, H., Huang, P., and Zhang, W. (2010) ABCG2 reduces ROS-mediated toxicity and inflammation: a potential role in Alzheimers disease J. Neurochem. 114, 1590-1604
-
(2010)
J. Neurochem.
, vol.114
, pp. 1590-1604
-
-
Shen, S.1
Callaghan, D.2
Juzwik, C.3
Xiong, H.4
Huang, P.5
Zhang, W.6
-
127
-
-
0034753508
-
Role of ABCG1 and other ABCG family members in lipid metabolism
-
Schmitz, G., Langmann, T., and Heimerl, S. (2001) Role of ABCG1 and other ABCG family members in lipid metabolism J. Lipid Res. 42, 1513-1520
-
(2001)
J. Lipid Res.
, vol.42
, pp. 1513-1520
-
-
Schmitz, G.1
Langmann, T.2
Heimerl, S.3
-
128
-
-
42049122331
-
ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain
-
Wang, N., Yvan-Charvet, L., Lutjohann, D., Mulder, M., Vanmierlo, T., Kim, T. W., and Tall, A. R. (2008) ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain FASEB J. 22, 1073-1082
-
(2008)
FASEB J.
, vol.22
, pp. 1073-1082
-
-
Wang, N.1
Yvan-Charvet, L.2
Lutjohann, D.3
Mulder, M.4
Vanmierlo, T.5
Kim, T.W.6
Tall, A.R.7
-
129
-
-
38049098102
-
ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2
-
Tarr, P. T. and Edwards, P. A. (2008) ABCG1 and ABCG4 are coexpressed in neurons and astrocytes of the CNS and regulate cholesterol homeostasis through SREBP-2 J. Lipid Res. 49, 169-182
-
(2008)
J. Lipid Res.
, vol.49
, pp. 169-182
-
-
Tarr, P.T.1
Edwards, P.A.2
-
130
-
-
34248144337
-
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein
-
Tansley, G. H., Burgess, B. L., Bryan, M. T., Su, Y., Hirsch-Reinshagen, V., Pearce, J., Chan, J. Y., Wilkinson, A., Evans, J., Naus, K. E., McIsaac, S., Bromley, K., Song, W., Yang, H. C., Wang, N., DeMattos, R. B., and Wellington, C. L. (2007) The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein J. Lipid Res. 48, 1022-1034
-
(2007)
J. Lipid Res.
, vol.48
, pp. 1022-1034
-
-
Tansley, G.H.1
Burgess, B.L.2
Bryan, M.T.3
Su, Y.4
Hirsch-Reinshagen, V.5
Pearce, J.6
Chan, J.Y.7
Wilkinson, A.8
Evans, J.9
Naus, K.E.10
McIsaac, S.11
Bromley, K.12
Song, W.13
Yang, H.C.14
Wang, N.15
Demattos, R.B.16
Wellington, C.L.17
-
131
-
-
45449115529
-
ATP-binding cassette transporter G4 is highly expressed in microglia in Alzheimers brain
-
Uehara, Y., Yamada, T., Baba, Y., Miura, S., Abe, S., Kitajima, K., Higuchi, M. A., Iwamoto, T., and Saku, K. (2008) ATP-binding cassette transporter G4 is highly expressed in microglia in Alzheimers brain Brain Res. 1217, 239-246
-
(2008)
Brain Res.
, vol.1217
, pp. 239-246
-
-
Uehara, Y.1
Yamada, T.2
Baba, Y.3
Miura, S.4
Abe, S.5
Kitajima, K.6
Higuchi, M.A.7
Iwamoto, T.8
Saku, K.9
-
132
-
-
6344265573
-
Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain
-
Nies, A. T., Jedlitschky, G., Konig, J., Herold-Mende, C., Steiner, H. H., Schmitt, H. P., and Keppler, D. (2004) Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain Neuroscience 129, 349-360
-
(2004)
Neuroscience
, vol.129
, pp. 349-360
-
-
Nies, A.T.1
Jedlitschky, G.2
Konig, J.3
Herold-Mende, C.4
Steiner, H.H.5
Schmitt, H.P.6
Keppler, D.7
-
133
-
-
32344432793
-
Differential, strain-specific cellular and subcellular distribution of multidrug transporters in murine choroid plexus and blood-brain barrier
-
Soontornmalai, A., Vlaming, M. L., and Fritschy, J. M. (2006) Differential, strain-specific cellular and subcellular distribution of multidrug transporters in murine choroid plexus and blood-brain barrier Neuroscience 138, 159-169
-
(2006)
Neuroscience
, vol.138
, pp. 159-169
-
-
Soontornmalai, A.1
Vlaming, M.L.2
Fritschy, J.M.3
-
134
-
-
27244436425
-
Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats
-
van Vliet, E. A., Redeker, S., Aronica, E., Edelbroek, P. M., and Gorter, J. A. (2005) Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats Epilepsia 46, 1569-1580
-
(2005)
Epilepsia
, vol.46
, pp. 1569-1580
-
-
Van Vliet, E.A.1
Redeker, S.2
Aronica, E.3
Edelbroek, P.M.4
Gorter, J.A.5
-
135
-
-
0141790752
-
Involvement of multidrug resistance associated protein 1 (Mrp1) in the efflux transport of 17beta estradiol-D-17beta-glucuronide (E217betaG) across the blood-brain barrier
-
Sugiyama, D., Kusuhara, H., Lee, Y. J., and Sugiyama, Y. (2003) Involvement of multidrug resistance associated protein 1 (Mrp1) in the efflux transport of 17beta estradiol-D-17beta-glucuronide (E217betaG) across the blood-brain barrier Pharm. Res. 20, 1394-1400
-
(2003)
Pharm. Res.
, vol.20
, pp. 1394-1400
-
-
Sugiyama, D.1
Kusuhara, H.2
Lee, Y.J.3
Sugiyama, Y.4
-
136
-
-
0033616684
-
Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier
-
Rao, V. V., Dahlheimer, J. L., Bardgett, M. E., Snyder, A. Z., Finch, R. A., Sartorelli, A. C., and Piwnica-Worms, D. (1999) Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier Proc. Natl. Acad. Sci. U.S.A. 96, 3900-3905
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 3900-3905
-
-
Rao, V.V.1
Dahlheimer, J.L.2
Bardgett, M.E.3
Snyder, A.Z.4
Finch, R.A.5
Sartorelli, A.C.6
Piwnica-Worms, D.7
-
137
-
-
29244441701
-
ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier
-
Bronger, H., Konig, J., Kopplow, K., Steiner, H. H., Ahmadi, R., Herold-Mende, C., Keppler, D., and Nies, A. T. (2005) ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier Cancer Res. 65, 11419-11428
-
(2005)
Cancer Res.
, vol.65
, pp. 11419-11428
-
-
Bronger, H.1
Konig, J.2
Kopplow, K.3
Steiner, H.H.4
Ahmadi, R.5
Herold-Mende, C.6
Keppler, D.7
Nies, A.T.8
-
138
-
-
0033975098
-
Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier
-
Wijnholds, J., deLange, E. C., Scheffer, G. L., van den Berg, D. J., Mol, C. A., van der Valk, M., Schinkel, A. H., Scheper, R. J., Breimer, D. D., and Borst, P. (2000) Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier J. Clin. Invest. 105, 279-285
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 279-285
-
-
Wijnholds, J.1
Delange, E.C.2
Scheffer, G.L.3
Van Den Berg, D.J.4
Mol, C.A.5
Van Der Valk, M.6
Schinkel, A.H.7
Scheper, R.J.8
Breimer, D.D.9
Borst, P.10
-
139
-
-
0034815579
-
Transport of fluorescein in MDCKII-MRP1 transfected cells and mrp1-knockout mice
-
Sun, H., Johnson, D. R., Finch, R. A., Sartorelli, A. C., Miller, D. W., and Elmquist, W. F. (2001) Transport of fluorescein in MDCKII-MRP1 transfected cells and mrp1-knockout mice Biochem. Biophys. Res. Commun. 284, 863-869
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.284
, pp. 863-869
-
-
Sun, H.1
Johnson, D.R.2
Finch, R.A.3
Sartorelli, A.C.4
Miller, D.W.5
Elmquist, W.F.6
-
140
-
-
0038353599
-
Apparent lack of Mrp1-mediated efflux at the luminal side of mouse blood-brain barrier endothelial cells
-
Cisternino, S., Rousselle, C., Lorico, A., Rappa, G., and Scherrmann, J. M. (2003) Apparent lack of Mrp1-mediated efflux at the luminal side of mouse blood-brain barrier endothelial cells Pharm. Res. 20, 904-909
-
(2003)
Pharm. Res.
, vol.20
, pp. 904-909
-
-
Cisternino, S.1
Rousselle, C.2
Lorico, A.3
Rappa, G.4
Scherrmann, J.M.5
-
141
-
-
11144261790
-
Oxidatively modified GST and MRP1 in Alzheimers disease brain: Implications for accumulation of reactive lipid peroxidation products
-
Sultana, R. and Butterfield, D. A. (2004) Oxidatively modified GST and MRP1 in Alzheimers disease brain: implications for accumulation of reactive lipid peroxidation products Neurochem. Res. 29, 2215-2220
-
(2004)
Neurochem. Res.
, vol.29
, pp. 2215-2220
-
-
Sultana, R.1
Butterfield, D.A.2
-
142
-
-
0036753272
-
Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimers disease brain contribute to neuronal death
-
Butterfield, D. A., Castegna, A., Lauderback, C. M., and Drake, J. (2002) Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimers disease brain contribute to neuronal death Neurobiol. Aging 23, 655-664
-
(2002)
Neurobiol. Aging
, vol.23
, pp. 655-664
-
-
Butterfield, D.A.1
Castegna, A.2
Lauderback, C.M.3
Drake, J.4
-
143
-
-
0031980065
-
Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimers disease
-
Markesbery, W. R. and Lovell, M. A. (1998) Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimers disease Neurobiol. Aging 19, 33-36
-
(1998)
Neurobiol. Aging
, vol.19
, pp. 33-36
-
-
Markesbery, W.R.1
Lovell, M.A.2
-
144
-
-
0034667741
-
Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures
-
Lovell, M. A., Xie, C., and Markesbery, W. R. (2000) Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures Free Radical Biol. Med. 29, 714-720
-
(2000)
Free Radical Biol. Med.
, vol.29
, pp. 714-720
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
145
-
-
0034834620
-
Increased oxidative stress in Alzheimers disease as assessed with 4-hydroxynonenal but not malondialdehyde
-
McGrath, L. T., McGleenon, B. M., Brennan, S., McColl, D., Mc, I. S., and Passmore, A. P. (2001) Increased oxidative stress in Alzheimers disease as assessed with 4-hydroxynonenal but not malondialdehyde QJM 94, 485-490
-
(2001)
QJM
, vol.94
, pp. 485-490
-
-
McGrath, L.T.1
McGleenon, B.M.2
Brennan, S.3
McColl, D.4
Mc, I.S.5
Passmore, A.P.6
-
146
-
-
0030714092
-
Elevated 4-hydroxynonenal in ventricular fluid in Alzheimers disease
-
Lovell, M. A., Ehmann, W. D., Mattson, M. P., and Markesbery, W. R. (1997) Elevated 4-hydroxynonenal in ventricular fluid in Alzheimers disease Neurobiol. Aging 18, 457-461
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 457-461
-
-
Lovell, M.A.1
Ehmann, W.D.2
Mattson, M.P.3
Markesbery, W.R.4
-
147
-
-
0031678044
-
Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimers disease
-
Lovell, M. A., Xie, C., and Markesbery, W. R. (1998) Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimers disease Neurology 51, 1562-1566
-
(1998)
Neurology
, vol.51
, pp. 1562-1566
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
148
-
-
80053387416
-
Cerebral amyloid-beta proteostasis is regulated by the membrane transport protein ABCC1 in mice
-
Krohn, M., Lange, C., Hofrichter, J., Scheffler, K., Stenzel, J., Steffen, J., Schumacher, T., Bruning, T., Plath, A. S., Alfen, F., Schmidt, A., Winter, F., Rateitschak, K., Wree, A., Gsponer, J., Walker, L. C., and Pahnke, J. (2011) Cerebral amyloid-beta proteostasis is regulated by the membrane transport protein ABCC1 in mice J. Clin. Invest. 121, 3924-3931
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3924-3931
-
-
Krohn, M.1
Lange, C.2
Hofrichter, J.3
Scheffler, K.4
Stenzel, J.5
Steffen, J.6
Schumacher, T.7
Bruning, T.8
Plath, A.S.9
Alfen, F.10
Schmidt, A.11
Winter, F.12
Rateitschak, K.13
Wree, A.14
Gsponer, J.15
Walker, L.C.16
Pahnke, J.17
|