Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7β-hydroxycholesterol

Current Eye Research

Volumn 33, Issue 9, 2008, Pages 769-781

  Malvitte, Laure ^a   Montange, Thomas ^a   Vejux, Anne ^a   Joffre, Corinne ^b   Bron, Alain ^c   Creuzot Garcher, Catherine ^c   Lizard, Gérard ^a,d  

^a UNIVERSITÉ DE BOURGOGNE   (France)

^b CEMAGREF   (France)

^c DIJON UNIVERSITY HOSPITAL   (France)

^d Chu   (France)

Author keywords

7 hydroxycholesterol; Apoptosis; Cell death; Cytotoxicity; Retinal pigment epithelial cells

Indexed keywords

25 HYDROXYCHOLESTEROL; 7BETA HYDROXYCHOLESTEROL; APOPTOSIS INDUCING FACTOR; BENZYLOXYCARBONYLPHENYLALANYLALANYL FLUOROMETHYL KETONE; CASPASE 3; CATHEPSIN B INHIBITOR; CYTOCHROME C;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LYSOSOME; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE POTENTIAL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY;

APOPTOSIS INDUCING FACTOR; BLOTTING, WESTERN; CASPASE 3; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROMES C; DIPEPTIDES; DNA FRAGMENTATION; ELECTROPHORESIS, AGAR GEL; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; HYDROXYCHOLESTEROLS; KETONES; LYSOSOMES; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; PIGMENT EPITHELIUM OF EYE;

EID: 51949086031     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.1080/02713680802337397     Document Type: Article

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