Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents

EMBO Molecular Medicine

Volumn 6, Issue 7, 2014, Pages 902-917

  Martin, Mauricio G ^a,b   Ahmed, Tariq ^b   Korovaichuk, Alejandra ^c   Venero, Cesar ^d   Menchón, Silvia A ^b,e   Salas, Isabel ^a   Munck, Sebastian ^b   Herreras, Oscar ^c   Balschun, Detlef ^b   Dotti, Carlos G ^a,b  

^a CSIC   (Spain)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c INSTITUTO CAJAL   (Spain)

^d UNIVERSIDAD NACIONAL DE EDUCACIÓN A DISTANCIA   (Spain)

^e UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

Aging; Cholesterol; Learning; LTD; PI3K

Indexed keywords

CHOLESTEROL; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR 2; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; AMPA RECEPTOR;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN SLICE; CELL MEMBRANE; COGNITION; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; HIPPOCAMPUS; INTERNALIZATION; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MALE; MAZE TEST; NERVE CELL MEMBRANE; NONHUMAN; POSTSYNAPTIC DENSITY; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; RAT; SPATIAL LEARNING; SPATIAL MEMORY; ANIMAL; CELL CULTURE; CYTOLOGY; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; WISTAR RAT;

AGING; ANIMALS; CELLS, CULTURED; CHOLESTEROL; COGNITION; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RECEPTORS, AMPA;

EID: 84903735981     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201303711     Document Type: Article

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