Changes in vascular risk factors from midlife to late life and white matter lesions: A 20-year follow-up study

Dementia and Geriatric Cognitive Disorders

Volumn 31, Issue 2, 2011, Pages 119-125

  Vuorinen, Miika ^e   Solomon, Alina ^a,e   Rovio, Suvi ^a   Nieminen, Lasse ^e   Kåreholt, Ingemar ^a   Tuomilehto, Jaakko ^b,c,d   Soininen, Hilkka ^e,f,g   Kivipelto, Miia ^a,e  

^a AGING RESEARCH CENTER   (Sweden)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d SOUTH OSTROBOTHNIA CENTRAL HOSPITAL   (Finland)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

^f UNIVERSITY OF TURKU   (Finland)

^g KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Apolipoprotein E; Blood pressure; Cholesterol; Obesity; Overweight; White matter lesions

Indexed keywords

ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; APOLIPOPROTEIN E; CHOLESTEROL;

ADULT; AGED; ANTIHYPERTENSIVE THERAPY; ARTICLE; BLOOD PRESSURE; BODY MASS; COMPUTED TOMOGRAPHY SCANNER; DISEASE SEVERITY; FEMALE; HEALTH SURVEY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; NERVOUS TISSUE; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RATING SCALE; RISK FACTOR; VASCULAR DISEASE; WHITE MATTER;

AGE FACTORS; AGED; AGING; APOLIPOPROTEINS E; BLOOD PRESSURE; BODY MASS INDEX; BRAIN; CARDIOVASCULAR DISEASES; CHOLESTEROL; COGNITION DISORDERS; DEMENTIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTENSION; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OBESITY; RISK FACTORS;

EID: 79151483170     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000323810     Document Type: Article

References (49)

1. Kivipelto M, Helkala EL, Laakso MP, Hanninen T, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissinen A: Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study. BMJ 2001; 322: 1447-1451. (Pubitemid 32575406)
2. Launer LJ, Ross GW, Petrovitch H, Masaki K, Foley D, White LR, Havlik RJ: Midlife blood pressure and dementia: the Honolulu-Asia aging study. Neurobiol Aging 2000; 21: 49-55. (Pubitemid 30224785)
3. Notkola IL, Sulkava R, Pekkanen J, Erkinjuntti T, Ehnholm C, Kivinen P, Tuomilehto J, Nissinen A: Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease. Neuroepidemiology 1998; 17: 14-20. (Pubitemid 28153361)
4. Kivipelto M, Ngandu T, Fratiglioni L, Viitanen M, Kareholt I, Winblad B, Helkala EL, Tuomilehto J, Soininen H, Nissinen A: Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol 2005; 62: 1556-1560. (Pubitemid 41434560)
5. Whitmer RA, Gunderson EP, Barrett-Connor E, Quesenberry CP Jr, Yaffe K: Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ 2005; 330: 1360.
6. Scheltens P, Barkhof F, Valk J, Algra PR, van der Hoop RG, Nauta J, Wolters EC: White matter lesions on magnetic resonance imaging in clinically diagnosed Alzheimer's disease. Evidence for heterogeneity. Brain 1992; 115: 735-748.
7. van der Flier WM, Barkhof F, Scheltens P: Shifting paradigms in dementia: toward stratification of diagnosis and treatment using MRI. Ann NY Acad Sci 2007; 1097: 215-224. (Pubitemid 47084890)
8. De Groot JC, De Leeuw FE, Oudkerk M, Van Gijn J, Hofman A, Jolles J, Breteler MM: Periventricular cerebral white matter lesions predict rate of cognitive decline. Ann Neurol 2002; 52: 335-341. (Pubitemid 35001500)
9. van Straaten EC, Harvey D, Scheltens P, Barkhof F, Petersen RC, Thal LJ, Jack CR Jr, DeCarli C, Alzheimer's Disease Cooperative Study Group: Periventricular white matter hyperintensities increase the likelihood of progression from amnestic mild cognitive impairment to dementia. J Neurol 2008; 255: 1302-1308.
10. Gunning-Dixon FM, Raz N: The cognitive correlates of white matter abnormalities in normal aging: a quantitative review. Neuropsychology 2000; 14: 224-232.
11. Inzitari D, Simoni M, Pracucci G, Poggesi A, Basile AM, Chabriat H, Erkinjuntti T, Fazekas F, Ferro JM, Hennerici M, Langhorne P, O'Brien J, Barkhof F, Visser MC, Wahlund LO, Waldemar G, Wallin A, Pantoni L, LADIS Study Group: Risk of rapid global functional decline in elderly patients with severe cerebral age-related white matter changes: the LADIS study. Arch Intern Med 2007; 167: 81-88. (Pubitemid 46072411)
12. Schmidt R, Fazekas F, Kapeller P, Schmidt H, Hartung HP: MRI white matter hyperintensities: three-year follow-up of the Austrian Stroke Prevention Study. Neurology 1999; 53: 132-139. (Pubitemid 29329661)
13. Dufouil C, de Kersaint-Gilly A, Besancon V,Levy C, Auffray E, Brunnereau L, Alperovitch A, Tzourio C: Longitudinal study of blood pressure and white matter hyperintensities: the EVA MRI Cohort. Neurology 2001; 56: 921-926. (Pubitemid 32290809)
14. Firbank MJ, Wiseman RM, Burton EJ, SaxbyBK, O'Brien JT, Ford GA: Brain atrophy and white matter hyperintensity change in older adults and relationship to blood pressure: brain atrophy, WMH change and blood pressure. J Neurol 2007; 254: 713-721. (Pubitemid 47012443)
15. Swan GE, DeCarli C, Miller BL, Reed T, Wolf PA, Jack LM, Carmelli D: Association of midlife blood pressure to late-life cognitive decline and brain morphology. Neurology 1998; 51: 986-993. (Pubitemid 28473389)
16. Carmelli D, Swan GE, Reed T, Wolf PA, Miller BL, DeCarli C: Midlife cardiovascular risk factors and brain morphology in identical older male twins. Neurology 1999; 52: 1119-1124. (Pubitemid 29177909)
17. de Leeuw FE, de Groot JC, Oudkerk M, Witteman JC, Hofman A, van Gijn J, Breteler MM: A follow-up study of blood pressure and cerebral white matter lesions. Ann Neurol 1999; 46: 827-833.
18. Gustafson DR, Steen B, Skoog I: Body mass index and white matter lesions in elderly women. An 18-year longitudinal study. Int Psychogeriatr 2004; 16: 327-336. (Pubitemid 39441496)
19. de Leeuw FE, Richard F, de Groot JC, van Duijn CM, Hofman A, Van Gijn J, Breteler MM: Interaction between hypertension, apoE, and cerebral white matter lesions. Stroke 2004; 35: 1057-1060. (Pubitemid 38543516)
20. Godin O, Tzourio C, Maillard P, Alperovitch A, Mazoyer B, Dufouil C: Apolipoprotein E genotype is related to progression of white matter lesion load. Stroke 2009; 40: 3186-3190.
21. Kuller LH, Shemanski L, Manolio T, Haan M, Fried L, Bryan N, Burke GL, Tracy R, Bha delia R: Relationship between ApoE, MRI findings, and cognitive function in the Cardiovascular Health Study. Stroke 1998; 29: 388-398. (Pubitemid 28086681)
22. Hirono N, Yasuda M, Tanimukai S, Kitagaki H, Mori E: Effect of the apolipoprotein E epsilon4 allele on white matter hyperintensities in dementia. Stroke 2000; 31: 1263-1268. (Pubitemid 30351243)
23. Vartiainen E, Puska P, Jousilahti P, KorhonenHJ, Tuomilehto J, Nissinen A: Twentyyear trends in coronary risk factors in north Karelia and in other areas of Finland. Int J Epidemiol 1994; 23: 495-504. (Pubitemid 24214853)
24. Kivipelto M, Helkala EL, Hanninen T, Laakso MP, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissinen A: Midlife vascular risk factors and late-life mild cognitive impairment: a population-based study. Neurology 2001; 56: 1683-1689. (Pubitemid 32574567)
25. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders ed 4. Washington, American Psychiatric Association, 1994.
26. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34: 939-944. (Pubitemid 14076461)
27. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E: Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 1999; 56: 303-308. (Pubitemid 29120227)
28. Kuulasmaa K, Tunstall-Pedoe H, Dobson A, Fortmann S, Sans S, Tolonen H, Evans A, Ferrario M, Tuomilehto J: Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations. Lancet 2000; 355: 675-687. (Pubitemid 30107623)
29. Tsukamoto K, Watanabe T, Matsushima T, Kinoshita M, Kato H, Hashimoto Y, Kurokawa K, Teramoto T: Determination by PCRRFLP of apo E genotype in a Japanese population. J Lab Clin Med 1993; 121: 598-602. (Pubitemid 23112654)
30. Wahlund LO, Barkhof F, Fazekas F, Bronge L, Augustin M, Sjogren M, Wallin A, Ader H, Leys D, Pantoni L, Pasquier F, Erkinjuntti T, Scheltens P, European Task Force on Age- Related White Matter Changes: A new rating scale for age-related white matter changes applicable to MRI and CT. Stroke 2001; 32: 1318-1322. (Pubitemid 32530416)
31. de Leeuw FE, de Groot JC, Achten E, Oudkerk M, Ramos LM, Heijboer R, Hofman A, Jolles J, van Gijn J, Breteler MM: Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study. J Neurol Neurosurg Psychiatry 2001; 70: 9-14. (Pubitemid 32096113)
32. Zhang J, Yu KF: What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA 1998; 280: 1690-1691. (Pubitemid 28532993)
33. Gazdzinski S, Kornak J, Weiner MW, Meyerhoff DJ: Body mass index and magnetic resonance markers of brain integrity in adults. Ann Neurol 2008; 63: 652-657.
34. van Dijk EJ, Breteler MM, Schmidt R, Berger K, Nilsson LG, Oudkerk M, Pajak A, Sans S, de Ridder M, Dufouil C, Fuhrer R, Giampaoli S, Launer LJ, Hofman A, CASCADE Consortium: The association between blood pressure, hypertension, and cerebral white matter lesions: cardiovascular determinants of dementia study. Hypertension 2004; 44: 625-630. (Pubitemid 39435230)
35. Qiu C, Winblad B, Fratiglioni L: Low diastolic pressure and risk of dementia in very old people: a longitudinal study. Dement Geriatr Cogn Disord 2009; 28: 213-219.
36. den Heijer T, Launer LJ, Prins ND, van Dijk EJ, Vermeer SE, Hofman A, Koudstaal PJ, Breteler MM: Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe. Neurology 2005; 64: 263-267.
37. Amarenco P, Labreuche J: Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention. Lancet Neurol 2009; 8: 453-463.
38. Mok VC, Lam WW, Fan YH, Wong A, Ng PW, Tsoi TH, Yeung V, Wong KS: Effects of statins on the progression of cerebral white matter lesion: post hoc analysis of the ROCAS (Regression of Cerebral Artery Stenosis) study. J Neurol 2009; 256: 750-757.
39. ten Dam VH, van den Heuvel DM, van Buchem MA, Westendorp RG, Bollen EL, Ford I, de Craen AJ, Blauw GJ, PROSPER Study Group: Effect of pravastatin on cerebral infarcts and white matter lesions. Neurology 2005; 64: 1807-1809. (Pubitemid 40695828)
40. De Michele M, Panico S, Iannuzzi A, Celentano E, Ciardullo AV, Galasso R, Sacchetti L, Zarrilli F, Bond MG, Rubba P: Association of obesity and central fat distribution with carotid artery wall thickening in middle-aged women. Stroke 2002; 33: 2923-2928. (Pubitemid 35462867)
41. Kivipelto M, Solomon A, Ngandu T: Vascular factors in Alzheimer's disease: from diagnostic dichotomy to integrative etiology; in Wahlund LO, Erkinjunti T, Gauthier S (eds): Vascular Cognitive Impairment in Clinical Practice. Cambridge, Cambridge University Press, 2009.
42. Trayhurn P, Wood IS: Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem Soc Trans 2005; 33: 1078-1081. (Pubitemid 41659117)
43. van Dijk EJ, Prins ND, Vermeer SE, Vrooman HA, Hofman A, Koudstaal PJ, Breteler MM: C-reactive protein and cerebral small-vessel disease: the Rotterdam Scan Study. Circulation 2005; 112: 900-905. (Pubitemid 41170078)
44. Macey PM, Henderson LA, Macey KE, Alger JR, Frysinger RC, Woo MA, Harper RK, Yan-Go FL, Harper RM: Brain morphology associated with obstructive sleep apnea. Am J Respir Crit Care Med 2002; 166: 1382-1387. (Pubitemid 35292706)
45. Morrell MJ, McRobbie DW, Quest RA, Cummin AR, Ghiassi R, Corfield DR: Changes in brain morphology associated with obstructive sleep apnea. Sleep Med 2003; 4: 451-454. (Pubitemid 37193029)
46. Gale SD, Hopkins RO: Effects of hypoxia onthe brain: neuroimaging and neuropsychological findings following carbon monoxide poisoning and obstructive sleep apnea. J Int Neuropsychol Soc 2004; 10: 60-71. (Pubitemid 38128463)
47. Zimmerman ME, Aloia MS: A review of neuroimaging in obstructive sleep apnea. J Clin Sleep Med 2006; 2: 461-471. (Pubitemid 44763809)
48. Macey PM, Kumar R, Woo MA, Valladares EM, Yan-Go FL, Harper RM: Brain structural changes in obstructive sleep apnea. Sleep 2008; 31: 967-977. (Pubitemid 351956936)
49. Wen W, Sachdev PS, Li JJ, Chen X, Anstey KJ: White matter hyperintensities in the forties: their prevalence and topography in an epidemiological sample aged 44-48. Hum Brain Mapp 2009; 30: 1155-1167.