메뉴 건너뛰기




Volumn 123, Issue , 2014, Pages 55-76

Drugs, genes and the blues: Pharmacogenetics of the antidepressant response from mouse to man

Author keywords

Animal model; Antidepressant; Depression; Personalised medicine; Pharmacogenetics; Treatment resistant depression

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOL METHYLTRANSFERASE; CYTOCHROME P450; DOPAMINE; DOPAMINE TRANSPORTER; GLUTAMATE RECEPTOR; MICRORNA; MULTIDRUG RESISTANCE PROTEIN 1; NORADRENALIN; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN 3 RECEPTOR; SEROTONIN 6 RECEPTOR; SEROTONIN TRANSPORTER; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 2; VESICULAR MONOAMINE TRANSPORTER 2;

EID: 84905239159     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2013.10.015     Document Type: Review
Times cited : (15)

References (419)
  • 1
    • 40149097433 scopus 로고    scopus 로고
    • Selective Loss of Brain-Derived Neurotrophic Factor in the Dentate Gyrus Attenuates Antidepressant Efficacy
    • DOI 10.1016/j.biopsych.2007.09.019, PII S0006322307008943
    • M. Adachi, M. Barrot, A.E. Autry, D. Theobald, and L.M. Monteggia Selective loss of brain-derived neurotrophic factor in the dentate gyrus attenuates antidepressant efficacy Biol Psychiatry 63 2008 642 649 (Pubitemid 351329281)
    • (2008) Biological Psychiatry , vol.63 , Issue.7 , pp. 642-649
    • Adachi, M.1    Barrot, M.2    Autry, A.E.3    Theobald, D.4    Monteggia, L.M.5
  • 3
    • 9144264524 scopus 로고    scopus 로고
    • 5-HT1A receptors, gene repression, and depression: Guilt by association
    • DOI 10.1177/1073858404267382
    • P.R. Albert, and S. Lemonde 5-HT1A receptors, gene repression, and depression: guilt by association Neuroscientist 10 2004 575 593 (Pubitemid 39546399)
    • (2004) Neuroscientist , vol.10 , Issue.6 , pp. 575-593
    • Albert, P.R.1    Lemonde, S.2
  • 5
    • 0033710657 scopus 로고    scopus 로고
    • CYP2D6 inhibition by fluoxetine, paroxetine, sertraline, and venlafaxine in a crossover study: Intraindividual variability and plasma concentration correlations
    • C.L. Alfaro, Y.W. Lam, J. Simpson, and L. Ereshefsky CYP2D6 inhibition by fluoxetine, paroxetine, sertraline, and venlafaxine in a crossover study: intraindividual variability and plasma concentration correlations J Clin Pharmacol 40 2000 58 66
    • (2000) J Clin Pharmacol , vol.40 , pp. 58-66
    • Alfaro, C.L.1    Lam, Y.W.2    Simpson, J.3    Ereshefsky, L.4
  • 6
    • 70349574008 scopus 로고    scopus 로고
    • Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients
    • A. Alkelai, L. Greenbaum, A. Rigbi, K. Kanyas, and B. Lerer Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients Psychopharmacology (Berl) 206 2009 491 499
    • (2009) Psychopharmacology (Berl) , vol.206 , pp. 491-499
    • Alkelai, A.1    Greenbaum, L.2    Rigbi, A.3    Kanyas, K.4    Lerer, B.5
  • 7
    • 0344825356 scopus 로고    scopus 로고
    • P-glycoprotein: From genomics to mechanism
    • DOI 10.1038/sj.onc.1206948, Drug Resistance
    • S.V. Ambudkar, C. Kimchi-Sarfaty, Z.E. Sauna, and M.M. Gottesman P-glycoprotein: from genomics to mechanism Oncogene 22 2003 7468 7485 (Pubitemid 37487170)
    • (2003) Oncogene , vol.22 , Issue.47 REV. ISS. 6 , pp. 7468-7485
    • Ambudkar, S.V.1    Kimchi-Sarfaty, C.2    Sauna, Z.E.3    Gottesman, M.M.4
  • 8
    • 7444232259 scopus 로고    scopus 로고
    • Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice
    • DOI 10.1126/science.1101678
    • M.S. Ansorge, M. Zhou, A. Lira, R. Hen, and J.A. Gingrich Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice Science 306 2004 879 881 (Pubitemid 39446998)
    • (2004) Science , vol.306 , Issue.5697 , pp. 879-881
    • Ansorge, M.S.1    Zhou, M.2    Lira, A.3    Hen, R.4    Gingrich, J.A.5
  • 9
    • 38149041752 scopus 로고    scopus 로고
    • Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice
    • M.S. Ansorge, E. Morelli, and J.A. Gingrich Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice J Neurosci 28 2008 199 207
    • (2008) J Neurosci , vol.28 , pp. 199-207
    • Ansorge, M.S.1    Morelli, E.2    Gingrich, J.A.3
  • 10
    • 17744397364 scopus 로고    scopus 로고
    • 1A receptor and serotonin transporter genes in the clinical outcome of major depressive patients treated with citalopram
    • DOI 10.1177/0269881105049037
    • B. Arias, R. Catalan, C. Gasto, B. Gutierrez, and L. Fananas Evidence for a combined genetic effect of the 5-HT(1A) receptor and serotonin transporter genes in the clinical outcome of major depressive patients treated with citalopram J Psychopharmacol 19 2005 166 172 (Pubitemid 40577221)
    • (2005) Journal of Psychopharmacology , vol.19 , Issue.2 , pp. 166-172
    • Arias, B.1    Catalan, R.2    Gasto, C.3    Gutierrez, B.4    Fananas, L.5
  • 11
    • 31944448412 scopus 로고    scopus 로고
    • Analysis of COMT gene (Val 158 Met polymorphism) in the clinical response to SSRIs in depressive patients of European origin
    • DOI 10.1016/j.jad.2005.11.008, PII S0165032705003435
    • B. Arias, A. Serretti, C. Lorenzi, C. Gasto, R. Catalan, and L. Fananas Analysis of COMT gene (Val 158 Met polymorphism) in the clinical response to SSRIs in depressive patients of European origin J Affect Disord 90 2006 251 256 (Pubitemid 43185979)
    • (2006) Journal of Affective Disorders , vol.90 , Issue.2-3 , pp. 251-256
    • Arias, B.1    Serretti, A.2    Lorenzi, C.3    Gasto, C.4    Catalan, R.5    Fananas, L.6
  • 12
    • 84870380950 scopus 로고    scopus 로고
    • TPH1, MAOA, serotonin receptor 2A and 2C genes in citalopram response: Possible effect in melancholic and psychotic depression
    • B. Arias, C. Fabbri, F. Gressier, A. Serretti, M. Mitjans, and C. Gasto et al. TPH1, MAOA, serotonin receptor 2A and 2C genes in citalopram response: possible effect in melancholic and psychotic depression Neuropsychobiology 67 2013 41 47
    • (2013) Neuropsychobiology , vol.67 , pp. 41-47
    • Arias, B.1    Fabbri, C.2    Gressier, F.3    Serretti, A.4    Mitjans, M.5    Gasto, C.6
  • 13
    • 79960057257 scopus 로고    scopus 로고
    • NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
    • A.E. Autry, M. Adachi, E. Nosyreva, E.S. Na, M.F. Los, and P.F. Cheng et al. NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses Nature 475 2011 91 95
    • (2011) Nature , vol.475 , pp. 91-95
    • Autry, A.E.1    Adachi, M.2    Nosyreva, E.3    Na, E.S.4    Los, M.F.5    Cheng, P.F.6
  • 14
    • 33846271368 scopus 로고    scopus 로고
    • Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein
    • DOI 10.1016/j.neuropharm.2006.07.038, PII S002839080600270X
    • S. Baltes, A.M. Gastens, M. Fedrowitz, H. Potschka, V. Kaever, and W. Loscher Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein Neuropharmacology 52 2007 333 346 (Pubitemid 46123353)
    • (2007) Neuropharmacology , vol.52 , Issue.2 , pp. 333-346
    • Baltes, S.1    Gastens, A.M.2    Fedrowitz, M.3    Potschka, H.4    Kaever, V.5    Loscher, W.6
  • 15
    • 33846118697 scopus 로고    scopus 로고
    • PolymiRTS Database: Linking polymorphisms in microRNA target sites with complex traits
    • L. Bao, M. Zhou, L. Wu, L. Lu, D. Goldowitz, and R.W. Williams et al. PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits Nucleic Acids Res 35 2007 D51 D54
    • (2007) Nucleic Acids Res , vol.35
    • Bao, L.1    Zhou, M.2    Wu, L.3    Lu, L.4    Goldowitz, D.5    Williams, R.W.6
  • 16
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-HT receptors and their function
    • DOI 10.1016/S0028-3908(99)00010-6, PII S0028390899000106
    • N.M. Barnes, and T. Sharp A review of central 5-HT receptors and their function Neuropharmacology 38 1999 1083 1152 (Pubitemid 29292403)
    • (1999) Neuropharmacology , vol.38 , Issue.8 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 17
    • 77956677763 scopus 로고    scopus 로고
    • MiR-16 targets the serotonin transporter: A new facet for adaptive responses to antidepressants
    • A. Baudry, S. Mouillet-Richard, B. Schneider, J.M. Launay, and O. Kellermann miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants Science 329 2010 1537 1541
    • (2010) Science , vol.329 , pp. 1537-1541
    • Baudry, A.1    Mouillet-Richard, S.2    Schneider, B.3    Launay, J.M.4    Kellermann, O.5
  • 19
    • 41949102371 scopus 로고    scopus 로고
    • Serotonin receptor 1A-1019C/G variant: Impact on antidepressant pharmacoresponse in melancholic depression?
    • B.T. Baune, C. Hohoff, T. Roehrs, J. Deckert, V. Arolt, and K. Domschke Serotonin receptor 1A-1019C/G variant: impact on antidepressant pharmacoresponse in melancholic depression? Neurosci Lett 436 2008 111 115
    • (2008) Neurosci Lett , vol.436 , pp. 111-115
    • Baune, B.T.1    Hohoff, C.2    Roehrs, T.3    Deckert, J.4    Arolt, V.5    Domschke, K.6
  • 21
    • 0142072078 scopus 로고    scopus 로고
    • Antidepressant effects of light therapy combined with sleep deprivation are influenced by a functional polymorphism within the promoter of the serotonin transporter gene
    • DOI 10.1016/S0006-3223(02)01894-2
    • F. Benedetti, C. Colombo, A. Serretti, C. Lorenzi, A. Pontiggia, and B. Barbini et al. Antidepressant effects of light therapy combined with sleep deprivation are influenced by a functional polymorphism within the promoter of the serotonin transporter gene Biol Psychiatry 54 2003 687 692 (Pubitemid 37281384)
    • (2003) Biological Psychiatry , vol.54 , Issue.7 , pp. 687-692
    • Benedetti, F.1    Colombo, C.2    Serretti, A.3    Lorenzi, C.4    Pontiggia, A.5    Barbini, B.6    Smeraldi, E.7
  • 22
    • 60449108060 scopus 로고    scopus 로고
    • The catechol-O-methyltransferase Val(108/158)Met polymorphism affects antidepressant response to paroxetine in a naturalistic setting
    • F. Benedetti, C. Colombo, A. Pirovano, E. Marino, and E. Smeraldi The catechol-O-methyltransferase Val(108/158)Met polymorphism affects antidepressant response to paroxetine in a naturalistic setting Psychopharmacology (Berl) 203 2009 155 160
    • (2009) Psychopharmacology (Berl) , vol.203 , pp. 155-160
    • Benedetti, F.1    Colombo, C.2    Pirovano, A.3    Marino, E.4    Smeraldi, E.5
  • 23
    • 72449150176 scopus 로고    scopus 로고
    • Acute antidepressant response to sleep deprivation combined with light therapy is influenced by the catechol-O-methyltransferase Val(108/158)Met polymorphism
    • F. Benedetti, B. Barbini, A. Bernasconi, M.C. Fulgosi, S. Dallaspezia, and C. Gavinelli et al. Acute antidepressant response to sleep deprivation combined with light therapy is influenced by the catechol-O-methyltransferase Val(108/158)Met polymorphism J Affect Disord 121 2010 68 72
    • (2010) J Affect Disord , vol.121 , pp. 68-72
    • Benedetti, F.1    Barbini, B.2    Bernasconi, A.3    Fulgosi, M.C.4    Dallaspezia, S.5    Gavinelli, C.6
  • 24
    • 3242699529 scopus 로고    scopus 로고
    • 3 receptor differentially affects behavior of males and females in the Porsolt forced swim and defensive withdrawal tests
    • DOI 10.1016/j.bbr.2004.01.018, PII S0166432804000257
    • S. Bhatnagar, N. Nowak, L. Babich, and L. Bok Deletion of the 5-HT3 receptor differentially affects behavior of males and females in the Porsolt forced swim and defensive withdrawal tests Behav Brain Res 153 2004 527 535 (Pubitemid 38953130)
    • (2004) Behavioural Brain Research , vol.153 , Issue.2 , pp. 527-535
    • Bhatnagar, S.1    Nowak, N.2    Babich, L.3    Bok, L.4
  • 25
    • 70350731477 scopus 로고    scopus 로고
    • The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
    • E.B. Binder The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders Psychoneuroendocrinology 34 Suppl. 1 2009 S186 S195
    • (2009) Psychoneuroendocrinology , vol.34 , Issue.SUPPL. 1
    • Binder, E.B.1
  • 27
    • 24044460136 scopus 로고    scopus 로고
    • Biogenic amine neurotransmitter transporters: Just when you thought you knew them
    • R.D. Blakely, L.J. Defelice, and A. Galli Biogenic amine neurotransmitter transporters: just when you thought you knew them Physiology (Bethesda) 20 2005 225 231 (Pubitemid 41215196)
    • (2005) Physiology , Issue.4 , pp. 225-231
    • Blakely, R.D.1    DeFelice, L.J.2    Galli, A.3
  • 30
    • 72449155342 scopus 로고    scopus 로고
    • Association study of paroxetine therapeutic response with SERT gene polymorphisms in patients with major depressive disorder
    • N. Bozina, A.M. Peles, M. Sagud, H. Bilusic, and M. Jakovljevic Association study of paroxetine therapeutic response with SERT gene polymorphisms in patients with major depressive disorder World J Biol Psychiatry 2007 1 8
    • (2007) World J Biol Psychiatry , pp. 1-8
    • Bozina, N.1    Peles, A.M.2    Sagud, M.3    Bilusic, H.4    Jakovljevic, M.5
  • 31
    • 48249094539 scopus 로고    scopus 로고
    • Association study of paroxetine therapeutic response with SERT gene polymorphisms in patients with major depressive disorder
    • N. Bozina, A.M. Peles, M. Sagud, H. Bilusic, and M. Jakovljevic Association study of paroxetine therapeutic response with SERT gene polymorphisms in patients with major depressive disorder World J Biol Psychiatry 9 2008 190 197
    • (2008) World J Biol Psychiatry , vol.9 , pp. 190-197
    • Bozina, N.1    Peles, A.M.2    Sagud, M.3    Bilusic, H.4    Jakovljevic, M.5
  • 32
    • 80052459230 scopus 로고    scopus 로고
    • A genome-wide significant linkage for severe depression on chromosome 3: The depression network study
    • G. Breen, B.T. Webb, A.W. Butler, E.J. van den Oord, F. Tozzi, and N. Craddock et al. A genome-wide significant linkage for severe depression on chromosome 3: the depression network study Am J Psychiatry 168 2011 840 847
    • (2011) Am J Psychiatry , vol.168 , pp. 840-847
    • Breen, G.1    Webb, B.T.2    Butler, A.W.3    Van Den Oord, E.J.4    Tozzi, F.5    Craddock, N.6
  • 33
    • 84889885853 scopus 로고    scopus 로고
    • The clinical application of ABCB1 genotyping in antidepressant treatment: A pilot study
    • B. Breitenstein, S. Scheuer, H. Pfister, M. Uhr, S. Lucae, and F. Holsboer et al. The clinical application of ABCB1 genotyping in antidepressant treatment: a pilot study CNS Spectr 2013 1 11
    • (2013) CNS Spectr , pp. 1-11
    • Breitenstein, B.1    Scheuer, S.2    Pfister, H.3    Uhr, M.4    Lucae, S.5    Holsboer, F.6
  • 34
    • 38649105517 scopus 로고    scopus 로고
    • Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR)
    • DOI 10.1007/s10519-007-9172-1
    • B.H. Brummett, S.H. Boyle, I.C. Siegler, C.M. Kuhn, A. Ashley-Koch, and C.R. Jonassaint et al. Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR) Behav Genet 38 2008 34 43 (Pubitemid 351164912)
    • (2008) Behavior Genetics , vol.38 , Issue.1 , pp. 34-43
    • Brummett, B.H.1    Boyle, S.H.2    Siegler, I.C.3    Kuhn, C.M.4    Ashley-Koch, A.5    Jonassaint, C.R.6    Zuchner, S.7    Collins, A.8    Williams, R.B.9
  • 35
    • 84857409667 scopus 로고    scopus 로고
    • Species comparison of in vivo P-glycoprotein-mediated brain efflux using mdr1a-deficient rats and mice
    • C. Bundgaard, C.J. Jensen, and M. Garmer Species comparison of in vivo P-glycoprotein-mediated brain efflux using mdr1a-deficient rats and mice Drug Metab Dispos 40 2012 461 466
    • (2012) Drug Metab Dispos , vol.40 , pp. 461-466
    • Bundgaard, C.1    Jensen, C.J.2    Garmer, M.3
  • 37
    • 79952487192 scopus 로고    scopus 로고
    • Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in rats
    • G.V. Carr, L.E. Schechter, and I. Lucki Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in rats Psychopharmacology (Berl) 213 2011 499 507
    • (2011) Psychopharmacology (Berl) , vol.213 , pp. 499-507
    • Carr, G.V.1    Schechter, L.E.2    Lucki, I.3
  • 38
    • 0029066498 scopus 로고
    • Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA
    • O. Cases, I. Seif, J. Grimsby, P. Gaspar, K. Chen, and S. Pournin et al. Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA Science 268 1995 1763 1766
    • (1995) Science , vol.268 , pp. 1763-1766
    • Cases, O.1    Seif, I.2    Grimsby, J.3    Gaspar, P.4    Chen, K.5    Pournin, S.6
  • 40
    • 84856230496 scopus 로고    scopus 로고
    • Genetic ablation of the GluK4 kainate receptor subunit causes anxiolytic and antidepressant-like behavior in mice
    • J.S. Catches, J. Xu, and A. Contractor Genetic ablation of the GluK4 kainate receptor subunit causes anxiolytic and antidepressant-like behavior in mice Behav Brain Res 228 2012 406 414
    • (2012) Behav Brain Res , vol.228 , pp. 406-414
    • Catches, J.S.1    Xu, J.2    Contractor, A.3
  • 43
    • 77957336025 scopus 로고    scopus 로고
    • Brain derived neurotrophic factor gene polymorphism (Val66Met) and short-term antidepressant response in major depressive disorder
    • M.H. Chi, H.H. Chang, S.Y. Lee, I.H. Lee, P.W. Gean, and Y.K. Yang et al. Brain derived neurotrophic factor gene polymorphism (Val66Met) and short-term antidepressant response in major depressive disorder J Affect Disord 126 2010 430 435
    • (2010) J Affect Disord , vol.126 , pp. 430-435
    • Chi, M.H.1    Chang, H.H.2    Lee, S.Y.3    Lee, I.H.4    Gean, P.W.5    Yang, Y.K.6
  • 44
    • 24944471356 scopus 로고    scopus 로고
    • Serotonin receptor 2A gene polymorphism (- 1438A/G) and short-term treatment response to citalopram
    • M.J. Choi, R.H. Kang, B.J. Ham, H.Y. Jeong, and M.S. Lee Serotonin receptor 2A gene polymorphism (- 1438A/G) and short-term treatment response to citalopram Neuropsychobiology 52 2005 155 162
    • (2005) Neuropsychobiology , vol.52 , pp. 155-162
    • Choi, M.J.1    Kang, R.H.2    Ham, B.J.3    Jeong, H.Y.4    Lee, M.S.5
  • 45
    • 33750371336 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder
    • M.J. Choi, R.H. Kang, S.W. Lim, K.S. Oh, and M.S. Lee Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder Brain Res 1118 2006 176 182
    • (2006) Brain Res , vol.1118 , pp. 176-182
    • Choi, M.J.1    Kang, R.H.2    Lim, S.W.3    Oh, K.S.4    Lee, M.S.5
  • 46
    • 67649726888 scopus 로고    scopus 로고
    • Verapamil in treatment resistant depression: A role for the P-glycoprotein transporter?
    • G. Clarke, S.M. O'Mahony, J.F. Cryan, and T.G. Dinan Verapamil in treatment resistant depression: a role for the P-glycoprotein transporter? Hum Psychopharmacol 24 2009 217 223
    • (2009) Hum Psychopharmacol , vol.24 , pp. 217-223
    • Clarke, G.1    O'Mahony, S.M.2    Cryan, J.F.3    Dinan, T.G.4
  • 49
    • 0345830631 scopus 로고    scopus 로고
    • Physiological Roles and Therapeutic Potential of Metabotropic Glutamate Receptors
    • DOI 10.1196/annals.1300.002
    • P.J. Conn Physiological roles and therapeutic potential of metabotropic glutamate receptors Ann N Y Acad Sci. 1003 2003 12 21 (Pubitemid 38083042)
    • (2003) Annals of the New York Academy of Sciences , vol.1003 , pp. 12-21
    • Conn, P.J.1
  • 51
    • 33646344731 scopus 로고    scopus 로고
    • The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: Evidence and lessons
    • N. Craddock, M.J. Owen, and M.C. O'Donovan The catechol-O-methyl transferase (COMT) gene as a candidate for psychiatric phenotypes: evidence and lessons Mol Psychiatry 11 2006 446 458
    • (2006) Mol Psychiatry , vol.11 , pp. 446-458
    • Craddock, N.1    Owen, M.J.2    O'Donovan, M.C.3
  • 53
    • 33748175773 scopus 로고    scopus 로고
    • Pharmacogenomic evaluation of the antidepressant citalopram in the mouse tail suspension test
    • DOI 10.1038/sj.npp.1301065, PII 1301065
    • J.J. Crowley, E.S. Brodkin, J.A. Blendy, W.H. Berrettini, and I. Lucki Pharmacogenomic evaluation of the antidepressant citalopram in the mouse tail suspension test Neuropsychopharmacology 31 2006 2433 2442 (Pubitemid 44607061)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.11 , pp. 2433-2442
    • Crowley, J.J.1    Brodkin, E.S.2    Blendy, J.A.3    Berrettini, W.H.4    Lucki, I.5
  • 54
    • 55049103994 scopus 로고    scopus 로고
    • Variation in the genes encoding vesicular monoamine transporter 2 and beta-1 adrenergic receptor and antidepressant treatment outcome
    • J.J. Crowley, R.H. Lipsky, I. Lucki, and W.H. Berrettini Variation in the genes encoding vesicular monoamine transporter 2 and beta-1 adrenergic receptor and antidepressant treatment outcome Psychiatr Genet 18 2008 248 251
    • (2008) Psychiatr Genet , vol.18 , pp. 248-251
    • Crowley, J.J.1    Lipsky, R.H.2    Lucki, I.3    Berrettini, W.H.4
  • 55
    • 26044460006 scopus 로고    scopus 로고
    • Model organisms: The ascent of mouse: Advances in modelling human depression and anxiety
    • DOI 10.1038/nrd1825, PII N1825
    • J.F. Cryan, and A. Holmes The ascent of mouse: advances in modelling human depression and anxiety Nat Rev Drug Discov 4 2005 775 790 (Pubitemid 43090498)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.9 , pp. 775-790
    • Cryan, J.F.1    Holmes, A.2
  • 56
    • 11144230982 scopus 로고    scopus 로고
    • B receptors in anxiety and depression
    • DOI 10.1016/j.tips.2004.11.004, PII S0165614704003104
    • J.F. Cryan, and K. Kaupmann Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression Trends Pharmacol Sci 26 2005 36 43 (Pubitemid 40052708)
    • (2005) Trends in Pharmacological Sciences , vol.26 , Issue.1 , pp. 36-43
    • Cryan, J.F.1    Kaupmann, K.2
  • 57
    • 0034074370 scopus 로고    scopus 로고
    • 5-HT(1A) and beyond: The role of serotonin and its receptors in depression and the antidepressant response
    • DOI 10.1002/(SICI)1099-1077(2 00003)15:2<113::A ID-HUP150>3.0.CO;2- W
    • J.F. Cryan, and B.E. Leonard 5-HT1A and beyond: the role of serotonin and its receptors in depression and the antidepressant response Hum Psychopharmacol 15 2000 113 135 (Pubitemid 30199285)
    • (2000) Human Psychopharmacology , vol.15 , Issue.2 , pp. 113-135
    • Cryan, J.F.1    Leonard, B.E.2
  • 58
    • 0034670389 scopus 로고    scopus 로고
    • 5-HT4 receptors do not mediate the antidepressant-like behavioral effects of fluoxetine in a modified forced swim test
    • J.F. Cryan, and I. Lucki 5-HT4 receptors do not mediate the antidepressant-like behavioral effects of fluoxetine in a modified forced swim test Eur J Pharmacol 409 2000 295 299
    • (2000) Eur J Pharmacol , vol.409 , pp. 295-299
    • Cryan, J.F.1    Lucki, I.2
  • 59
    • 0033681079 scopus 로고    scopus 로고
    • Antidepressant-like behavioral effects mediated by 5- hydroxytryptamine(2C) receptors
    • J.F. Cryan, and I. Lucki Antidepressant-like behavioral effects mediated by 5-hydroxytryptamine(2C) receptors J Pharmacol Exp Ther 295 2000 1120 1126
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 1120-1126
    • Cryan, J.F.1    Lucki, I.2
  • 60
  • 62
    • 19944380200 scopus 로고    scopus 로고
    • The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice
    • DOI 10.1016/j.neubiorev.2005.03.009, PII S0149763405000382, Animal Models of Depression and Antidepressant Activity
    • J.F. Cryan, C. Mombereau, and A. Vassout The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice Neurosci Biobehav Rev 29 2005 571 625 (Pubitemid 40755457)
    • (2005) Neuroscience and Biobehavioral Reviews , vol.29 , Issue.4-5 , pp. 571-625
    • Cryan, J.F.1    Mombereau, C.2    Vassout, A.3
  • 65
    • 84903853704 scopus 로고    scopus 로고
    • Locally increased P-glycoprotein function in major depression: A PET study with [C-11]verapamil as a probe for P-glycoprotein function in the blood-brain barrier
    • O.L. de Klerk, A.T.M. Willemsen, M. Roosink, A.L. Bartels, N.H. Hendrikse, and F.J. Bosker et al. Locally increased P-glycoprotein function in major depression: a PET study with [C-11]verapamil as a probe for P-glycoprotein function in the blood-brain barrier Int J Neuropsychopharmacol 12 2009 895 904
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 895-904
    • De Klerk, O.L.1    Willemsen, A.T.M.2    Roosink, M.3    Bartels, A.L.4    Hendrikse, N.H.5    Bosker, F.J.6
  • 66
    • 84881128550 scopus 로고    scopus 로고
    • ABCB1 gene variants influence tolerance to selective serotonin reuptake inhibitors in a large sample of Dutch cases with major depressive disorder
    • O.L. de Klerk, I.M. Nolte, P.M. Bet, F.J. Bosker, H. Snieder, and J.A. den Boer et al. ABCB1 gene variants influence tolerance to selective serotonin reuptake inhibitors in a large sample of Dutch cases with major depressive disorder Pharmacogenomics J 13 4 2013 349 353
    • (2013) Pharmacogenomics J , vol.13 , Issue.4 , pp. 349-353
    • De Klerk, O.L.1    Nolte, I.M.2    Bet, P.M.3    Bosker, F.J.4    Snieder, H.5    Den Boer, J.A.6
  • 67
    • 29544449443 scopus 로고    scopus 로고
    • Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19
    • DOI 10.1176/appi.psy.47.1.75
    • J. de Leon, S.C. Armstrong, and K.L. Cozza Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19 Psychosomatics 47 2006 75 85 (Pubitemid 43017126)
    • (2006) Psychosomatics , vol.47 , Issue.1 , pp. 75-85
    • De Leon, J.1    Armstrong, S.C.2    Cozza, K.L.3
  • 68
    • 80053574439 scopus 로고    scopus 로고
    • Association between CYP2C19*17 and metabolism of amitriptyline, citalopram and clomipramine in Dutch hospitalized patients
    • A. de Vos, J. van der Weide, and H.M. Loovers Association between CYP2C19*17 and metabolism of amitriptyline, citalopram and clomipramine in Dutch hospitalized patients Pharmacogenomics J 11 2011 359 367
    • (2011) Pharmacogenomics J , vol.11 , pp. 359-367
    • De Vos, A.1    Van Der Weide, J.2    Loovers, H.M.3
  • 69
    • 0026005750 scopus 로고
    • Rapid serotonin depletion as a provocative challenge test for patients with major depression: Relevance to antidepressant action and the neurobiology of depression
    • P.L. Delgado, L.H. Price, H.L. Miller, R.M. Salomon, J. Licinio, and J.H. Krystal et al. Rapid serotonin depletion as a provocative challenge test for patients with major depression: relevance to antidepressant action and the neurobiology of depression Psychopharmacol Bull 27 1991 321 330
    • (1991) Psychopharmacol Bull , vol.27 , pp. 321-330
    • Delgado, P.L.1    Price, L.H.2    Miller, H.L.3    Salomon, R.M.4    Licinio, J.5    Krystal, J.H.6
  • 70
    • 33745698333 scopus 로고    scopus 로고
    • No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjects
    • R. Delorme, C.M. Durand, C. Betancur, M. Wagner, S. Ruhrmann, and H.J. Grabe et al. No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjects Biol Psychiatry 60 2006 202 203
    • (2006) Biol Psychiatry , vol.60 , pp. 202-203
    • Delorme, R.1    Durand, C.M.2    Betancur, C.3    Wagner, M.4    Ruhrmann, S.5    Grabe, H.J.6
  • 71
    • 80053081437 scopus 로고    scopus 로고
    • Antidepressant treatment and altered CYP2D6 activity: Are pharmacokinetic variations clinically relevant?
    • I. D'Empaire, C.J. Guico-Pabia, and S.H. Preskorn Antidepressant treatment and altered CYP2D6 activity: are pharmacokinetic variations clinically relevant? J Psychiatr Pract 17 2011 330 339
    • (2011) J Psychiatr Pract , vol.17 , pp. 330-339
    • D'Empaire, I.1    Guico-Pabia, C.J.2    Preskorn, S.H.3
  • 73
    • 84860351187 scopus 로고    scopus 로고
    • Impact of the BDNF Val66Met polymorphism on cognition: Implications for behavioral genetics
    • I. Dincheva, C.E. Glatt, and F.S. Lee Impact of the BDNF Val66Met polymorphism on cognition: implications for behavioral genetics Neuroscientist 18 2012 439 451
    • (2012) Neuroscientist , vol.18 , pp. 439-451
    • Dincheva, I.1    Glatt, C.E.2    Lee, F.S.3
  • 74
    • 45549090747 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphisms and sertraline response in major depression patients
    • DOI 10.1089/gte.2007.0089
    • O. Dogan, N. Yuksel, M.A. Ergun, A. Yilmaz, M.N. Ilhan, and H.E. Karslioglu et al. Serotonin transporter gene polymorphisms and sertraline response in major depression patients Genet Test 12 2008 225 231 (Pubitemid 351860438)
    • (2008) Genetic Testing , vol.12 , Issue.2 , pp. 225-231
    • Dogan, O.1    Yuksel, N.2    Ergun, M.A.3    Yilmaz, A.4    Ilhan, M.N.5    Karslioglu, H.E.6    Koc, A.7    Menevse, A.8
  • 75
    • 40849142489 scopus 로고    scopus 로고
    • 2B receptors are required for 3,4- methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro
    • DOI 10.1523/JNEUROSCI.5723-07.2008
    • S. Doly, E. Valjent, V. Setola, J. Callebert, D. Herve, and J.M. Launay et al. Serotonin 5-HT2B receptors are required for 3,4- methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro J Neurosci 28 2008 2933 2940 (Pubitemid 351398883)
    • (2008) Journal of Neuroscience , vol.28 , Issue.11 , pp. 2933-2940
    • Doly, S.1    Valjent, E.2    Setola, V.3    Callebert, J.4    Herve, D.5    Launay, J.-M.6    Maroteaux, L.7
  • 77
    • 77949580959 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor (BDNF) gene: No major impact on antidepressant treatment response
    • K. Domschke, B. Lawford, G. Laje, K. Berger, R. Young, and P. Morris et al. Brain-derived neurotrophic factor (BDNF) gene: no major impact on antidepressant treatment response Int J Neuropsychopharmacol 13 2010 93 101
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 93-101
    • Domschke, K.1    Lawford, B.2    Laje, G.3    Berger, K.4    Young, R.5    Morris, P.6
  • 78
    • 70450222707 scopus 로고    scopus 로고
    • Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: Association with major depression and antidepressant response in Mexican-Americans
    • C. Dong, M.L. Wong, and J. Licinio Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans Mol Psychiatry 14 2009 1105 1118
    • (2009) Mol Psychiatry , vol.14 , pp. 1105-1118
    • Dong, C.1    Wong, M.L.2    Licinio, J.3
  • 80
    • 80054875166 scopus 로고    scopus 로고
    • The genetics of antipsychotic induced tremors: A genome-wide pathway analysis on the STEP-BD SCP sample
    • A. Drago, C. Crisafulli, and A. Serretti The genetics of antipsychotic induced tremors: a genome-wide pathway analysis on the STEP-BD SCP sample Am J Med Genet B Neuropsychiatr Genet 156B 2011 975 986
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156 B , pp. 975-986
    • Drago, A.1    Crisafulli, C.2    Serretti, A.3
  • 81
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • R.S. Duman, and L.M. Monteggia A neurotrophic model for stress-related mood disorders Biol Psychiatry 59 2006 1116 1127
    • (2006) Biol Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 82
    • 4344641185 scopus 로고    scopus 로고
    • The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder
    • L.K. Durham, S.M. Webb, P.M. Milos, C.M. Clary, and A.B. Seymour The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder Psychopharmacology (Berl) 174 2004 525 529 (Pubitemid 39119341)
    • (2004) Psychopharmacology , vol.174 , Issue.4 , pp. 525-529
    • Durham, L.K.1    Webb, S.M.2    Milos, P.M.3    Clary, C.M.4    Seymour, A.B.5
  • 83
    • 33846003865 scopus 로고    scopus 로고
    • Review of the pharmacology and clinical profile of bupropion, an antidepressant and tobacco use cessation agent
    • DOI 10.1111/j.1527-3458.2006.00178.x
    • L.P. Dwoskin, A.S. Rauhut, K.A. King-Pospisil, and M.T. Bardo Review of the pharmacology and clinical profile of bupropion, an antidepressant and tobacco use cessation agent CNS Drug Rev 12 2006 178 207 (Pubitemid 46047787)
    • (2006) CNS Drug Reviews , vol.12 , Issue.3-4 , pp. 178-207
    • Dwoskin, L.P.1    Rauhut, A.S.2    King-Pospisil, K.A.3    Bardo, M.T.4
  • 85
    • 80051796941 scopus 로고    scopus 로고
    • TREK-1 isoforms generated by alternative translation initiation display different susceptibility to the antidepressant fluoxetine
    • M. Eckert, B. Egenberger, F. Doring, and E. Wischmeyer TREK-1 isoforms generated by alternative translation initiation display different susceptibility to the antidepressant fluoxetine Neuropharmacology 61 2011 918 923
    • (2011) Neuropharmacology , vol.61 , pp. 918-923
    • Eckert, M.1    Egenberger, B.2    Doring, F.3    Wischmeyer, E.4
  • 87
    • 14944375269 scopus 로고    scopus 로고
    • Influence of P-glycoprotein inhibition on the distribution of the tricyclic antidepressant nortriptyline over the blood-brain barrier
    • DOI 10.1002/hup.667
    • T.B. Ejsing, and K. Linnet Influence of P-glycoprotein inhibition on the distribution of the tricyclic antidepressant nortriptyline over the blood-brain barrier Hum Psychopharmacol 20 2005 149 153 (Pubitemid 40372491)
    • (2005) Human Psychopharmacology , vol.20 , Issue.2 , pp. 149-153
    • Ejsing, T.B.1    Linnet, K.2
  • 88
    • 33745660599 scopus 로고    scopus 로고
    • The influence of P-glycoprotein on cerebral and hepatic concentrations of nortriptyline and its metabolites
    • T.B. Ejsing, J. Hasselstrom, and K. Linnet The influence of P-glycoprotein on cerebral and hepatic concentrations of nortriptyline and its metabolites Drug Metabol Drug Interact 21 2006 139 162 (Pubitemid 43971436)
    • (2006) Drug Metabolism and Drug Interactions , vol.21 , Issue.3-4 , pp. 139-162
    • Ejsing, T.B.1    Hasselstrom, J.2    Linnet, K.3
  • 89
    • 84873406626 scopus 로고    scopus 로고
    • FKBP5 genetic variation: Association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder
    • K.A. Ellsworth, I. Moon, B.W. Eckloff, B.L. Fridley, G.D. Jenkins, and A. Batzler et al. FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder Pharmacogenet Genomics 23 2013 156 166
    • (2013) Pharmacogenet Genomics , vol.23 , pp. 156-166
    • Ellsworth, K.A.1    Moon, I.2    Eckloff, B.W.3    Fridley, B.L.4    Jenkins, G.D.5    Batzler, A.6
  • 90
    • 67349229539 scopus 로고    scopus 로고
    • What happens to patients with treatment-resistant depression? A systematic review of medium to long term outcome studies
    • A. Fekadu, S.C. Wooderson, K. Markopoulo, C. Donaldson, A. Papadopoulos, and A.J. Cleare What happens to patients with treatment-resistant depression? A systematic review of medium to long term outcome studies J Affect Disord 116 2009 4 11
    • (2009) J Affect Disord , vol.116 , pp. 4-11
    • Fekadu, A.1    Wooderson, S.C.2    Markopoulo, K.3    Donaldson, C.4    Papadopoulos, A.5    Cleare, A.J.6
  • 92
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • W. Filipowicz, S.N. Bhattacharyya, and N. Sonenberg Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9 2008 102 114
    • (2008) Nat Rev Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 93
    • 0032841176 scopus 로고    scopus 로고
    • An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells
    • DOI 10.1016/S0014-5793(99)01150-3, PII S0014579399011503
    • C.E. Fiskerstrand, E.A. Lovejoy, and J.P. Quinn An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells FEBS Lett 458 1999 171 174 (Pubitemid 29428177)
    • (1999) FEBS Letters , vol.458 , Issue.2 , pp. 171-174
    • Fiskerstrand, C.E.1    Lovejoy, E.A.2    Quinn, J.P.3
  • 95
    • 70749088207 scopus 로고    scopus 로고
    • Evaluation of the influence of sex and CYP2C19 and CYP2D6 polymorphisms in the disposition of citalopram
    • S. Fudio, A.M. Borobia, E. Pinana, E. Ramirez, B. Tabares, and P. Guerra et al. Evaluation of the influence of sex and CYP2C19 and CYP2D6 polymorphisms in the disposition of citalopram Eur J Pharmacol 626 2010 200 204
    • (2010) Eur J Pharmacol , vol.626 , pp. 200-204
    • Fudio, S.1    Borobia, A.M.2    Pinana, E.3    Ramirez, E.4    Tabares, B.5    Guerra, P.6
  • 97
    • 34248140167 scopus 로고    scopus 로고
    • Dose-dependent effects of the 3435 C>T genotype of ABCB1 gene on the steady-state plasma concentration of fluvoxamine in psychiatric patients
    • DOI 10.1097/FTD.0b013e318038d835, PII 0000769120070400000006
    • N. Fukui, Y. Suzuki, K. Sawamura, T. Sugai, J. Watanabe, and Y. Inoue et al. Dose-dependent effects of the 3435 C > T genotype of ABCB1 gene on the steady-state plasma concentration of fluvoxamine in psychiatric patients Ther Drug Monit 29 2007 185 189 (Pubitemid 46716184)
    • (2007) Therapeutic Drug Monitoring , vol.29 , Issue.2 , pp. 185-189
    • Fukui, N.1    Suzuki, Y.2    Sawamura, K.3    Sugai, T.4    Watanabe, J.5    Inoue, Y.6    Someya, T.7
  • 99
    • 0024356185 scopus 로고
    • Double-blind, placebo-controlled study of nortriptyline in depressed children using a 'fixed plasma level' design
    • B. Geller, T.B. Cooper, H.G. McCombs, D. Graham, and J. Wells Double-blind, placebo-controlled study of nortriptyline in depressed children using a "fixed plasma level" design Psychopharmacol Bull 25 1989 101 108 (Pubitemid 19179170)
    • (1989) Psychopharmacology Bulletin , vol.25 , Issue.1 , pp. 101-108
    • Geller, B.1    Cooper, T.B.2    McCombs, H.G.3    Graham, D.4    Wells, J.5
  • 100
    • 0025045318 scopus 로고
    • Double-blind placebo-controlled study of nortriptyline in depressed adolescents using a ''fixed plasma level'' design
    • B. Geller, T.B. Cooper, D.L. Graham, F.A. Marsteller, and D.M. Bryant Double-blind placebo-controlled study of nortriptyline in depressed adolescents using a "fixed plasma level" design Psychopharmacol Bull 26 1990 85 90 (Pubitemid 20322251)
    • (1990) Psychopharmacology Bulletin , vol.26 , Issue.1 , pp. 85-90
    • Geller, B.1    Cooper, T.B.2    Graham, D.L.3    Marsteller, F.A.4    Bryant, D.M.5
  • 101
    • 84873348443 scopus 로고    scopus 로고
    • Common genetic variation and antidepressant efficacy in major depressive disorder: A meta-analysis of three genome-wide pharmacogenetic studies
    • GENDEP Investigators, MARS Investigators, and STAR*D Investigators
    • GENDEP Investigators, MARS Investigators, and STAR*D Investigators Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies Am J Psychiatry 170 2013 207 217
    • (2013) Am J Psychiatry , vol.170 , pp. 207-217
  • 102
    • 58149124253 scopus 로고    scopus 로고
    • CYP2D6 and ABCB1 genetic variability: Influence on paroxetine plasma level and therapeutic response
    • M. Gex-Fabry, C.B. Eap, B. Oneda, N. Gervasoni, J.M. Aubry, and G. Bondolfi et al. CYP2D6 and ABCB1 genetic variability: influence on paroxetine plasma level and therapeutic response Ther Drug Monit 30 2008 474 482
    • (2008) Ther Drug Monit , vol.30 , pp. 474-482
    • Gex-Fabry, M.1    Eap, C.B.2    Oneda, B.3    Gervasoni, N.4    Aubry, J.M.5    Bondolfi, G.6
  • 103
    • 33644811359 scopus 로고    scopus 로고
    • Response to Zhang et al. (2005): Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression
    • [Neuron. 2005;48:704-5; author reply 5-6]
    • C.E. Glatt, E. Carlson, T.R. Taylor, N. Risch, V.I. Reus, and C.A. Schaefer Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression Neuron 45 2005 11 16 [Neuron. 2005;48:704-5; author reply 5-6]
    • (2005) Neuron , vol.45 , pp. 11-16
    • Glatt, C.E.1    Carlson, E.2    Taylor, T.R.3    Risch, N.4    Reus, V.I.5    Schaefer, C.A.6
  • 106
    • 2442513407 scopus 로고    scopus 로고
    • P-glycoprotein reduces the ability of amitriptyline metabolites to cross the blood-brain barrier in mice after a 10-day administration of amitriptyline
    • DOI 10.1177/0269881104042831
    • M.T. Grauer, and M. Uhr P-glycoprotein reduces the ability of amitriptyline metabolites to cross the blood brain barrier in mice after a 10-day administration of amitriptyline J Psychopharmacol 18 2004 66 74 (Pubitemid 38623096)
    • (2004) Journal of Psychopharmacology , vol.18 , Issue.1 , pp. 66-74
    • Grauer, M.T.1    Uhr, M.2
  • 107
    • 78149361693 scopus 로고    scopus 로고
    • The role of clinical variables, neuropsychological performance and SLC6A4 and COMT gene polymorphisms on the prediction of early response to fluoxetine in major depressive disorder
    • E. Gudayol-Ferre, I. Herrera-Guzman, B. Camarena, C. Cortes-Penagos, J.E. Herrera-Abarca, and P. Martinez-Medina et al. The role of clinical variables, neuropsychological performance and SLC6A4 and COMT gene polymorphisms on the prediction of early response to fluoxetine in major depressive disorder J Affect Disord 127 2010 343 351
    • (2010) J Affect Disord , vol.127 , pp. 343-351
    • Gudayol-Ferre, E.1    Herrera-Guzman, I.2    Camarena, B.3    Cortes-Penagos, C.4    Herrera-Abarca, J.E.5    Martinez-Medina, P.6
  • 108
    • 84873743622 scopus 로고    scopus 로고
    • Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: Modulation by antidepressant treatment
    • G. Guidotti, F. Calabrese, C. Anacker, G. Racagni, C.M. Pariante, and M.A. Riva Glucocorticoid receptor and FKBP5 expression is altered following exposure to chronic stress: modulation by antidepressant treatment Neuropsychopharmacology 38 2013 616 627
    • (2013) Neuropsychopharmacology , vol.38 , pp. 616-627
    • Guidotti, G.1    Calabrese, F.2    Anacker, C.3    Racagni, G.4    Pariante, C.M.5    Riva, M.A.6
  • 109
    • 33748764379 scopus 로고    scopus 로고
    • 1A receptor knockout mice
    • DOI 10.1038/sj.npp.1301019, PII 1301019
    • J.P. Guilloux, D.J. David, B.P. Guiard, F. Chenu, C. Reperant, and M. Toth et al. Blockade of 5-HT1A receptors by (+/-)-pindolol potentiates cortical 5-HT outflow, but not antidepressant-like activity of paroxetine: microdialysis and behavioral approaches in 5-HT1A receptor knockout mice Neuropsychopharmacology 31 2006 2162 2172 (Pubitemid 44413193)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.10 , pp. 2162-2172
    • Guilloux, J.-P.1    David, D.J.P.2    Guiard, B.P.3    Chenu, F.4    Reperant, C.5    Toth, M.6    Bourin, M.7    Gardier, A.M.8
  • 110
    • 0037171846 scopus 로고    scopus 로고
    • Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims
    • DOI 10.1016/S0896-6273(02)00660-8
    • I. Gurevich, H. Tamir, V. Arango, A.J. Dwork, J.J. Mann, and C. Schmauss Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims Neuron 34 2002 349 356 (Pubitemid 34465494)
    • (2002) Neuron , vol.34 , Issue.3 , pp. 349-356
    • Gurevich, I.1    Tamir, H.2    Arango, V.3    Dwork, A.J.4    Mann, J.J.5    Schmauss, C.6
  • 111
    • 33845760846 scopus 로고    scopus 로고
    • Association between the tryptophan hydroxylase-1 gene A218C polymorphism and citalopram antidepressant response in a Korean population
    • B.J. Ham, B.C. Lee, J.W. Paik, R.H. Kang, M.J. Choi, and I.G. Choi et al. Association between the tryptophan hydroxylase-1 gene A218C polymorphism and citalopram antidepressant response in a Korean population Prog Neuropsychopharmacol Biol Psychiatry 31 2007 104 107
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 104-107
    • Ham, B.J.1    Lee, B.C.2    Paik, J.W.3    Kang, R.H.4    Choi, M.J.5    Choi, I.G.6
  • 112
    • 80052509542 scopus 로고    scopus 로고
    • A new lead from genetic studies in depressed siblings: Assessing studies of chromosome 3
    • S.P. Hamilton A new lead from genetic studies in depressed siblings: assessing studies of chromosome 3 Am J Psychiatry 168 2011 783 789
    • (2011) Am J Psychiatry , vol.168 , pp. 783-789
    • Hamilton, S.P.1
  • 113
    • 0035947012 scopus 로고    scopus 로고
    • 1A receptor deletion upon basal and fluoxetine-evoked 5-HT concentrations as revealed by in vivo microdialysis
    • DOI 10.1016/S0006-8993(01)02271-5, PII S0006899301022715
    • M. He, E. Sibille, D. Benjamin, M. Toth, and T. Shippenberg Differential effects of 5-HT1A receptor deletion upon basal and fluoxetine-evoked 5-HT concentrations as revealed by in vivo microdialysis Brain Res 902 2001 11 17 (Pubitemid 32499270)
    • (2001) Brain Research , vol.902 , Issue.1 , pp. 11-17
    • He, M.1    Sibille, E.2    Benjamin, D.3    Toth, M.4    Shippenberg, T.5
  • 116
    • 0030058366 scopus 로고    scopus 로고
    • The revised monoamine theory of depression: A modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans
    • G.R. Heninger, P.L. Delgado, and D.S. Charney The revised monoamine theory of depression: a modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans Pharmacopsychiatry 29 1996 2 11 (Pubitemid 26071332)
    • (1996) Pharmacopsychiatry , vol.29 , Issue.1 , pp. 2-11
    • Heninger, G.R.1    Delgado, P.L.2    Charney, D.S.3
  • 118
    • 68049127796 scopus 로고    scopus 로고
    • Genetic variation in brain-derived neurotrophic factor is associated with serotonin transporter but not serotonin-1A receptor availability in men
    • S. Henningsson, J. Borg, J. Lundberg, J. Bah, M. Lindstrom, and E. Ryding et al. Genetic variation in brain-derived neurotrophic factor is associated with serotonin transporter but not serotonin-1A receptor availability in men Biol Psychiatry 66 2009 477 485
    • (2009) Biol Psychiatry , vol.66 , pp. 477-485
    • Henningsson, S.1    Borg, J.2    Lundberg, J.3    Bah, J.4    Lindstrom, M.5    Ryding, E.6
  • 119
    • 59849100842 scopus 로고    scopus 로고
    • A functional dopamine-beta-hydroxylase gene promoter polymorphism is associated with impulsive personality styles, but not with affective disorders
    • C. Hess, A. Reif, A. Strobel, A. Boreatti-Hummer, M. Heine, and K.P. Lesch et al. A functional dopamine-beta-hydroxylase gene promoter polymorphism is associated with impulsive personality styles, but not with affective disorders J Neural Transm 116 2009 121 130
    • (2009) J Neural Transm , vol.116 , pp. 121-130
    • Hess, C.1    Reif, A.2    Strobel, A.3    Boreatti-Hummer, A.4    Heine, M.5    Lesch, K.P.6
  • 121
    • 0036897940 scopus 로고    scopus 로고
    • Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter
    • DOI 10.1016/S0893-133X(02)00374-3, PII S0893133X02003743
    • A. Holmes, R.J. Yang, D.L. Murphy, and J.N. Crawley Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter Neuropsychopharmacology 27 2002 914 923 (Pubitemid 35447628)
    • (2002) Neuropsychopharmacology , vol.27 , Issue.6 , pp. 914-923
    • Holmes, A.1    Yang, R.J.2    Murphy, D.L.3    Crawley, J.N.4
  • 122
    • 31044444151 scopus 로고    scopus 로고
    • Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder
    • DOI 10.1038/sj.tpj.6500340, PII 6500340
    • C.J. Hong, T.J. Chen, Y.W. Yu, and S.J. Tsai Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder Pharmacogenomics J 6 2006 27 33 (Pubitemid 43118308)
    • (2006) Pharmacogenomics Journal , vol.6 , Issue.1 , pp. 27-33
    • Hong, C.-J.1    Chen, T.-J.2    Yu, Y.W.-Y.3    Tsai, S.-J.4
  • 123
    • 68949155368 scopus 로고    scopus 로고
    • Pharmacogenomics of antidepressant drugs
    • S. Horstmann, and E.B. Binder Pharmacogenomics of antidepressant drugs Pharmacol Ther 124 2009 57 73
    • (2009) Pharmacol Ther , vol.124 , pp. 57-73
    • Horstmann, S.1    Binder, E.B.2
  • 124
    • 79958026754 scopus 로고    scopus 로고
    • Glucocorticoids as predictors of treatment response in depression
    • S. Horstmann, and E.B. Binder Glucocorticoids as predictors of treatment response in depression Harv Rev Psychiatry 19 2011 125 143
    • (2011) Harv Rev Psychiatry , vol.19 , pp. 125-143
    • Horstmann, S.1    Binder, E.B.2
  • 125
    • 75749127758 scopus 로고    scopus 로고
    • Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment
    • S. Horstmann, S. Lucae, A. Menke, J.M. Hennings, M. Ising, and D. Roeske et al. Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment Neuropsychopharmacology 35 2010 727 740
    • (2010) Neuropsychopharmacology , vol.35 , pp. 727-740
    • Horstmann, S.1    Lucae, S.2    Menke, A.3    Hennings, J.M.4    Ising, M.5    Roeske, D.6
  • 126
    • 0036119338 scopus 로고    scopus 로고
    • Molecular, pharmacological and functional diversity of 5-HT receptors
    • DOI 10.1016/S0091-3057(01)00746-8, PII S0091305701007468
    • D. Hoyer, J.P. Hannon, and G.R. Martin Molecular, pharmacological and functional diversity of 5-HT receptors Pharmacol Biochem Behav 71 2002 533 554 (Pubitemid 34219205)
    • (2002) Pharmacology Biochemistry and Behavior , vol.71 , Issue.4 , pp. 533-554
    • Hoyer, D.1    Hannon, J.P.2    Martin, G.R.3
  • 127
    • 33646072813 scopus 로고    scopus 로고
    • Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
    • X.Z. Hu, R.H. Lipsky, G. Zhu, L.A. Akhtar, J. Taubman, and B.D. Greenberg et al. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder Am J Hum Genet 78 2006 815 826
    • (2006) Am J Hum Genet , vol.78 , pp. 815-826
    • Hu, X.Z.1    Lipsky, R.H.2    Zhu, G.3    Akhtar, L.A.4    Taubman, J.5    Greenberg, B.D.6
  • 129
    • 33645097092 scopus 로고    scopus 로고
    • Augmentation by citalopram of risperidone-induced monoamine release in rat prefrontal cortex
    • M. Huang, J. Ichiwaka, Z. Li, J. Dai, and H.Y. Meltzer Augmentation by citalopram of risperidone-induced monoamine release in rat prefrontal cortex Psychopharmacology (Berl) 185 2006 274 281
    • (2006) Psychopharmacology (Berl) , vol.185 , pp. 274-281
    • Huang, M.1    Ichiwaka, J.2    Li, Z.3    Dai, J.4    Meltzer, H.Y.5
  • 131
    • 67349123686 scopus 로고    scopus 로고
    • Deficit in BDNF does not increase vulnerability to stress but dampens antidepressant-like effects in the unpredictable chronic mild stress
    • Y. Ibarguen-Vargas, A. Surget, P. Vourc'h, S. Leman, C.R. Andres, and A.M. Gardier et al. Deficit in BDNF does not increase vulnerability to stress but dampens antidepressant-like effects in the unpredictable chronic mild stress Behav Brain Res 202 2009 245 251
    • (2009) Behav Brain Res , vol.202 , pp. 245-251
    • Ibarguen-Vargas, Y.1    Surget, A.2    Vourc'H, P.3    Leman, S.4    Andres, C.R.5    Gardier, A.M.6
  • 133
    • 76749099733 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase val108/158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorder
    • A. Illi, E. Setala-Soikkeli, O. Kampman, M. Viikki, T. Nuolivirta, and O. Poutanen et al. Catechol-O-methyltransferase val108/158met genotype, major depressive disorder and response to selective serotonin reuptake inhibitors in major depressive disorder Psychiatry Res 176 2010 85 87
    • (2010) Psychiatry Res , vol.176 , pp. 85-87
    • Illi, A.1    Setala-Soikkeli, E.2    Kampman, O.3    Viikki, M.4    Nuolivirta, T.5    Poutanen, O.6
  • 134
    • 0037200634 scopus 로고    scopus 로고
    • A variable number of tandem repeats in the serotonin transporter gene does not affect the antidepressant response to fluvoxamine
    • K. Ito, K. Yoshida, K. Sato, H. Takahashi, M. Kamata, and H. Higuchi et al. A variable number of tandem repeats in the serotonin transporter gene does not affect the antidepressant response to fluvoxamine Psychiatry Res 111 2002 235 239
    • (2002) Psychiatry Res , vol.111 , pp. 235-239
    • Ito, K.1    Yoshida, K.2    Sato, K.3    Takahashi, H.4    Kamata, M.5    Higuchi, H.6
  • 135
    • 77950887549 scopus 로고    scopus 로고
    • A psychoneuroimmunological review on cytokines involved in antidepressant treatment response
    • D.G. Janssen, R.N. Caniato, J.C. Verster, and B.T. Baune A psychoneuroimmunological review on cytokines involved in antidepressant treatment response Hum Psychopharmacol 25 2010 201 215
    • (2010) Hum Psychopharmacol , vol.25 , pp. 201-215
    • Janssen, D.G.1    Caniato, R.N.2    Verster, J.C.3    Baune, B.T.4
  • 137
  • 139
    • 19344362051 scopus 로고    scopus 로고
    • Sex differences in the regulation of serotonergic transmission and behavior in 5-HT receptor knockout mice
    • DOI 10.1038/sj.npp.1300664
    • M.D. Jones, and I. Lucki Sex differences in the regulation of serotonergic transmission and behavior in 5-HT receptor knockout mice Neuropsychopharmacology 30 2005 1039 1047 (Pubitemid 40720961)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.6 , pp. 1039-1047
    • Jones, M.D.1    Lucki, I.2
  • 141
    • 0742305531 scopus 로고    scopus 로고
    • Age-dependent antidepressant pharmacogenomics: Polymorphisms of the serotonin transporter and G protein β3 subunit as predictors of response to fluoxetine and nortriptyline
    • DOI 10.1017/S1461145703003663
    • P.R. Joyce, R.T. Mulder, S.E. Luty, J.M. McKenzie, A.L. Miller, and G.R. Rogers et al. Age-dependent antidepressant pharmacogenomics: polymorphisms of the serotonin transporter and G protein beta3 subunit as predictors of response to fluoxetine and nortriptyline Int J Neuropsychopharmacol 6 2003 339 346 (Pubitemid 38146251)
    • (2003) International Journal of Neuropsychopharmacology , vol.6 , Issue.4 , pp. 339-346
    • Joyce, P.R.1    Mulder, R.T.2    Luty, S.E.3    McKenzie, J.M.4    Miller, A.L.5    Rogers, G.R.6    Kennedy, M.A.7
  • 142
    • 33748375576 scopus 로고    scopus 로고
    • Are serotonin transporter knockout mice 'depressed'? Hypoactivity but no anhedonia
    • DOI 10.1097/01.wnr.0000230514.08962.76, PII 0000175620060821000024
    • A.V. Kalueff, P.S. Gallagher, and D.L. Murphy Are serotonin transporter knockout mice 'depressed'?: Hypoactivity but no anhedonia Neuroreport 17 2006 1347 1351 (Pubitemid 44337080)
    • (2006) NeuroReport , vol.17 , Issue.12 , pp. 1347-1351
    • Kalueff, A.V.1    Gallagher, P.S.2    Murphy, D.L.3
  • 143
    • 37549038223 scopus 로고    scopus 로고
    • Effect of serotonin receptor 2A gene polymorphism on mirtazapine response in major depression
    • R.H. Kang, M.J. Choi, J.W. Paik, S.W. Hahn, and M.S. Lee Effect of serotonin receptor 2A gene polymorphism on mirtazapine response in major depression Int J Psychiatry Med 37 2007 315 329
    • (2007) Int J Psychiatry Med , vol.37 , pp. 315-329
    • Kang, R.H.1    Choi, M.J.2    Paik, J.W.3    Hahn, S.W.4    Lee, M.S.5
  • 144
    • 77955097341 scopus 로고    scopus 로고
    • Blood-brain barrier penetration of the enantiomers of venlafaxine and its metabolites in mice lacking P-glycoprotein
    • L. Karlsson, U. Schmitt, M. Josefsson, B. Carlsson, J. Ahlner, and F. Bengtsson et al. Blood-brain barrier penetration of the enantiomers of venlafaxine and its metabolites in mice lacking P-glycoprotein Eur Neuropsychopharmacol 20 2010 632 640
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 632-640
    • Karlsson, L.1    Schmitt, U.2    Josefsson, M.3    Carlsson, B.4    Ahlner, J.5    Bengtsson, F.6
  • 145
    • 79955575024 scopus 로고    scopus 로고
    • Effects on enantiomeric drug disposition and open-field behavior after chronic treatment with venlafaxine in the P-glycoprotein knockout mice model
    • L. Karlsson, C. Hiemke, B. Carlsson, M. Josefsson, J. Ahlner, and F. Bengtsson et al. Effects on enantiomeric drug disposition and open-field behavior after chronic treatment with venlafaxine in the P-glycoprotein knockout mice model Psychopharmacology (Berl) 215 2011 367 377
    • (2011) Psychopharmacology (Berl) , vol.215 , pp. 367-377
    • Karlsson, L.1    Hiemke, C.2    Carlsson, B.3    Josefsson, M.4    Ahlner, J.5    Bengtsson, F.6
  • 146
    • 84886783723 scopus 로고    scopus 로고
    • Altered brain concentrations of citalopram and escitalopram in P-glycoprotein deficient mice after acute and chronic treatment
    • 10.1016/j.euroneuro.2013.01.003 (in press)
    • L. Karlsson, B. Carlsson, C. Hiemke, J. Ahlner, F. Bengtsson, and U. Schmitt et al. Altered brain concentrations of citalopram and escitalopram in P-glycoprotein deficient mice after acute and chronic treatment Eur Neuropsychopharmacol 2013 10.1016/j.euroneuro.2013.01.003 (in press)
    • (2013) Eur Neuropsychopharmacol
    • Karlsson, L.1    Carlsson, B.2    Hiemke, C.3    Ahlner, J.4    Bengtsson, F.5    Schmitt, U.6
  • 147
    • 77951844279 scopus 로고    scopus 로고
    • Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder
    • M. Kato, and A. Serretti Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder Mol Psychiatry 15 2010 473 500
    • (2010) Mol Psychiatry , vol.15 , pp. 473-500
    • Kato, M.1    Serretti, A.2
  • 148
    • 33747396949 scopus 로고    scopus 로고
    • Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients
    • DOI 10.1159/000094727
    • M. Kato, T. Fukuda, M. Wakeno, K. Fukuda, G. Okugawa, and Y. Ikenaga et al. Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients Neuropsychobiology 53 2006 186 195 (Pubitemid 44252779)
    • (2006) Neuropsychobiology , vol.53 , Issue.4 , pp. 186-195
    • Kato, M.1    Fukuda, T.2    Wakeno, M.3    Fukuda, K.4    Okugawa, G.5    Ikenaga, Y.6    Yamashita, M.7    Takekita, Y.8    Nobuhara, K.9    Azuma, J.10    Kinoshita, T.11
  • 149
    • 42449103398 scopus 로고    scopus 로고
    • No association of TPH1 218A/C polymorphism with treatment response and intolerance to SSRIs in Japanese patients with major depression
    • DOI 10.1159/000119734
    • M. Kato, M. Wakeno, G. Okugawa, T. Fukuda, J. Azuma, and T. Kinoshita et al. No association of TPH1 218A/C polymorphism with treatment response and intolerance to SSRIs in Japanese patients with major depression Neuropsychobiology 56 2007 167 171 (Pubitemid 351567532)
    • (2007) Neuropsychobiology , vol.56 , Issue.4 , pp. 167-171
    • Kato, M.1    Wakeno, M.2    Okugawa, G.3    Fukuda, T.4    Azuma, J.5    Kinoshita, T.6    Serretti, A.7
  • 153
    • 1242269894 scopus 로고    scopus 로고
    • Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: Ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study
    • DOI 10.1007/s00228-003-0701-4
    • C. Kawanishi, S. Lundgren, H. Agren, and L. Bertilsson Increased incidence of CYP2D6 gene duplication in patients with persistent mood disorders: ultrarapid metabolism of antidepressants as a cause of nonresponse. A pilot study Eur J Clin Pharmacol 59 2004 803 807 (Pubitemid 38221657)
    • (2004) European Journal of Clinical Pharmacology , vol.59 , Issue.11 , pp. 803-807
    • Kawanishi, C.1    Lundgren, S.2    Agren, H.3    Bertilsson, L.4
  • 154
    • 79953042396 scopus 로고    scopus 로고
    • Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project
    • R. Keers, R. Uher, P. Huezo-Diaz, R. Smith, S. Jaffee, and M. Rietschel et al. Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project Pharmacogenomics J 11 2011 138 145
    • (2011) Pharmacogenomics J , vol.11 , pp. 138-145
    • Keers, R.1    Uher, R.2    Huezo-Diaz, P.3    Smith, R.4    Jaffee, S.5    Rietschel, M.6
  • 155
    • 84884671572 scopus 로고    scopus 로고
    • What psychiatric genetics has taught us about the nature of psychiatric illness and what is left to learn
    • K.S. Kendler What psychiatric genetics has taught us about the nature of psychiatric illness and what is left to learn Mol Psychiatry 18 10 2013 1058 1066
    • (2013) Mol Psychiatry , vol.18 , Issue.10 , pp. 1058-1066
    • Kendler, K.S.1
  • 156
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: A replication
    • DOI 10.1001/archpsyc.62.5.529
    • K.S. Kendler, J.W. Kuhn, J. Vittum, C.A. Prescott, and B. Riley The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication Arch Gen Psychiatry 62 2005 529 535 (Pubitemid 40628882)
    • (2005) Archives of General Psychiatry , vol.62 , Issue.5 , pp. 529-535
    • Kendler, K.S.1    Kuhn, J.W.2    Vittum, J.3    Prescott, C.A.4    Riley, B.5
  • 157
    • 0027524544 scopus 로고
    • Sex and depression in the National Comorbidity Survey I: Lifetime prevalence, chronicity and recurrence
    • DOI 10.1016/0165-0327(93)90026-G
    • R.C. Kessler, K.A. McGonagle, M. Swartz, D.G. Blazer, and C.B. Nelson Sex and depression in the National Comorbidity Survey. I: Lifetime prevalence, chronicity and recurrence J Affect Disord 29 1993 85 96 (Pubitemid 23334116)
    • (1993) Journal of Affective Disorders , vol.29 , Issue.2-3 , pp. 85-96
    • Kessler, R.C.1    McGonagle, K.A.2    Swartz, M.3    Blazer, D.G.4    Nelson, C.B.5
  • 161
    • 1842506233 scopus 로고    scopus 로고
    • Trimipramine pharmacokinetics after intravenous and oral administration in carriers of CYP2D6 genotypes predicting poor, extensive and ultrahigh activity
    • DOI 10.1097/00008571-200312000-00003
    • J. Kirchheiner, J. Sasse, I. Meineke, I. Roots, and J. Brockmoller Trimipramine pharmacokinetics after intravenous and oral administration in carriers of CYP2D6 genotypes predicting poor, extensive and ultrahigh activity Pharmacogenetics 13 2003 721 728 (Pubitemid 38429250)
    • (2003) Pharmacogenetics , vol.13 , Issue.12 , pp. 721-728
    • Kirchheiner, J.1    Sasse, J.2    Meineke, I.3    Roots, I.4    Brockmoller, J.5
  • 162
    • 8744224452 scopus 로고    scopus 로고
    • Impact of the CYP2D6 ultrarapid metabolizer genotype on mirtazapine pharmacokinetics and adverse events in healthy volunteers
    • DOI 10.1097/01.jcp.0000145341.30547.f0
    • J. Kirchheiner, H.B. Henckel, I. Meineke, I. Roots, and J. Brockmoller Impact of the CYP2D6 ultrarapid metabolizer genotype on mirtazapine pharmacokinetics and adverse events in healthy volunteers J Clin Psychopharmacol 24 2004 647 652 (Pubitemid 39518662)
    • (2004) Journal of Clinical Psychopharmacology , vol.24 , Issue.6 , pp. 647-652
    • Kirchheiner, J.1    Henckel, H.-B.2    Meineke, I.3    Roots, I.4    Brockmoller, J.5
  • 163
    • 33847281407 scopus 로고    scopus 로고
    • A 40-basepair VNTR polymorphism in the dopamine transporter (DAT1) gene and the rapid response to antidepressant treatment
    • DOI 10.1038/sj.tpj.6500398, PII 6500398
    • J. Kirchheiner, K. Nickchen, J. Sasse, M. Bauer, I. Roots, and J. Brockmoller A 40-basepair VNTR polymorphism in the dopamine transporter (DAT1) gene and the rapid response to antidepressant treatment Pharmacogenomics J 7 2007 48 55 (Pubitemid 46322079)
    • (2007) Pharmacogenomics Journal , vol.7 , Issue.1 , pp. 48-55
    • Kirchheiner, J.1    Nickchen, K.2    Sasse, J.3    Bauer, M.4    Roots, I.5    Brockmoller, J.6
  • 164
    • 77956573720 scopus 로고    scopus 로고
    • Pharmacogenetic study of serotonin 6 receptor gene with antidepressant response in major depressive disorder in the Japanese population
    • T. Kishi, Y. Fukuo, R. Yoshimura, T. Okochi, T. Kitajima, and H. Naitoh et al. Pharmacogenetic study of serotonin 6 receptor gene with antidepressant response in major depressive disorder in the Japanese population Hum Psychopharmacol 25 2010 481 486
    • (2010) Hum Psychopharmacol , vol.25 , pp. 481-486
    • Kishi, T.1    Fukuo, Y.2    Yoshimura, R.3    Okochi, T.4    Kitajima, T.5    Naitoh, H.6
  • 165
  • 166
    • 0034883141 scopus 로고    scopus 로고
    • 1B autoreceptors in different brain regions of the mouse
    • D.A. Knobelman, R. Hen, and I. Lucki Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse J Pharmacol Exp Ther 298 2001 1083 1091 (Pubitemid 32761924)
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.298 , Issue.3 , pp. 1083-1091
    • Knobelman, D.A.1    Hen, R.2    Lucki, I.3
  • 167
    • 77953721854 scopus 로고    scopus 로고
    • The impact of catechol-O-methyltransferase SNPs and haplotypes on treatment response phenotypes in major depressive disorder: A case-control association study
    • N.A. Kocabas, C. Faghel, M. Barreto, S. Kasper, S. Linotte, and J. Mendlewicz et al. The impact of catechol-O-methyltransferase SNPs and haplotypes on treatment response phenotypes in major depressive disorder: a case-control association study Int Clin Psychopharmacol 25 2010 218 227
    • (2010) Int Clin Psychopharmacol , vol.25 , pp. 218-227
    • Kocabas, N.A.1    Faghel, C.2    Barreto, M.3    Kasper, S.4    Linotte, S.5    Mendlewicz, J.6
  • 168
    • 0036900564 scopus 로고    scopus 로고
    • R-fluoxetine increases extracellular DA, NE, as well as 5-HT in rat prefrontal cortex and hypothalamus: An in vivo microdialysis and receptor binding study
    • DOI 10.1016/S0893-133X(02)00377-9, PII S0893133X02003779
    • S. Koch, K.W. Perry, D.L. Nelson, R.G. Conway, P.G. Threlkeld, and F.P. Bymaster R-fluoxetine increases extracellular DA, NE, as well as 5-HT in rat prefrontal cortex and hypothalamus: an in vivo microdialysis and receptor binding study Neuropsychopharmacology 27 2002 949 959 (Pubitemid 35447632)
    • (2002) Neuropsychopharmacology , vol.27 , Issue.6 , pp. 949-959
    • Koch, S.1    Perry, K.W.2    Nelson, D.L.3    Conway, R.G.4    Threlkeld, P.G.5    Bymaster, F.P.6
  • 169
    • 70349333224 scopus 로고    scopus 로고
    • Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b
    • S. Komagata, M. Nakajima, S. Takagi, T. Mohri, T. Taniya, and T. Yokoi Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b Mol Pharmacol 76 2009 702 709
    • (2009) Mol Pharmacol , vol.76 , pp. 702-709
    • Komagata, S.1    Nakajima, M.2    Takagi, S.3    Mohri, T.4    Taniya, T.5    Yokoi, T.6
  • 170
    • 31544454715 scopus 로고    scopus 로고
    • Enhanced BDNF signaling is associated with an antidepressant-like behavioral response and changes in brain monoamines
    • DOI 10.1007/s10571-005-8468-z
    • E. Koponen, T. Rantamaki, V. Voikar, T. Saarelainen, E. MacDonald, and E. Castren Enhanced BDNF signaling is associated with an antidepressant-like behavioral response and changes in brain monoamines Cell Mol Neurobiol 25 2005 973 980 (Pubitemid 43154821)
    • (2005) Cellular and Molecular Neurobiology , vol.25 , Issue.6 , pp. 973-980
    • Koponen, E.1    Rantamaki, T.2    Voikar, V.3    Saarelainen, T.4    MacDonald, E.5    Castren, E.6
  • 171
    • 51049104524 scopus 로고    scopus 로고
    • Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
    • O. Kovalchuk, J. Filkowski, J. Meservy, Y. Ilnytskyy, V.P. Tryndyak, and V.F. Chekhun et al. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin Mol Cancer Ther 7 2008 2152 2159
    • (2008) Mol Cancer Ther , vol.7 , pp. 2152-2159
    • Kovalchuk, O.1    Filkowski, J.2    Meservy, J.3    Ilnytskyy, Y.4    Tryndyak, V.P.5    Chekhun, V.F.6
  • 172
    • 24044520963 scopus 로고    scopus 로고
    • Sequence analysis of the serotonin transporter and associations with antidepressant response
    • DOI 10.1016/j.biopsych.2005.04.048, PII S0006322305005688
    • J.B. Kraft, S.L. Slager, P.J. McGrath, and S.P. Hamilton Sequence analysis of the serotonin transporter and associations with antidepressant response Biol Psychiatry 58 2005 374 381 (Pubitemid 41219705)
    • (2005) Biological Psychiatry , vol.58 , Issue.5 , pp. 374-381
    • Kraft, J.B.1    Slager, S.L.2    McGrath, P.J.3    Hamilton, S.P.4
  • 174
    • 0030004521 scopus 로고    scopus 로고
    • Human catechol-O-methyltransferase pharmacogenetics: Description of a functional polymorphism and its potential application to neuropsychiatric disorders
    • DOI 10.1097/00008571-199606000-00007
    • H.M. Lachman, D.F. Papolos, T. Saito, Y.M. Yu, C.L. Szumlanski, and R.M. Weinshilboum Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders Pharmacogenetics 6 1996 243 250 (Pubitemid 26226317)
    • (1996) Pharmacogenetics , vol.6 , Issue.3 , pp. 243-250
    • Lachman, H.M.1    Papolos, D.F.2    Saito, T.3    Yu, Y.-M.4    Szumlanski, C.L.5    Weinshilboum, R.M.6
  • 175
    • 33646365080 scopus 로고    scopus 로고
    • ABCB1 (P-glycoprotein/MDR1) gene G2677T/A sequence variation (polymorphism): Lack of association with side effects and therapeutic response in depressed inpatients treated with amitriptyline [2]
    • DOI 10.1373/clinchem.2006.066605
    • B. Laika, S. Leucht, and W. Steimer ABCB1 (P-glycoprotein/MDR1) gene G2677T/A sequence variation (polymorphism): lack of association with side effects and therapeutic response in depressed inpatients treated with amitriptyline Clin Chem 52 2006 893 895 (Pubitemid 43673271)
    • (2006) Clinical Chemistry , vol.52 , Issue.5 , pp. 893-895
    • Laika, B.1    Leucht, S.2    Steimer, W.3
  • 176
    • 84868208976 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients
    • G. Laje, N. Lally, D. Mathews, N. Brutsche, A. Chemerinski, and N. Akula et al. Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients Biol Psychiatry 72 2012 e27 e28
    • (2012) Biol Psychiatry , vol.72
    • Laje, G.1    Lally, N.2    Mathews, D.3    Brutsche, N.4    Chemerinski, A.5    Akula, N.6
  • 177
    • 0036021208 scopus 로고    scopus 로고
    • CYP2D6 inhibition by selective serotonin reuptake inhibitors: Analysis of achievable steady-state plasma concentrations and the effect of ultrarapid metabolism at CYP2D6
    • Y.W. Lam, A. Gaedigk, L. Ereshefsky, C.L. Alfaro, and J. Simpson CYP2D6 inhibition by selective serotonin reuptake inhibitors: analysis of achievable steady-state plasma concentrations and the effect of ultrarapid metabolism at CYP2D6 Pharmacotherapy 22 2002 1001 1006 (Pubitemid 34831295)
    • (2002) Pharmacotherapy , vol.22 , Issue.8 , pp. 1001-1006
    • Lam, Y.W.F.1    Gaedigk, A.2    Ereshefsky, L.3    Alfaro, C.L.4    Simpson, J.5
  • 179
    • 17144381701 scopus 로고    scopus 로고
    • Association between the 5-HT6 receptor C267T polymorphism and response to antidepressant treatment in major depressive disorder
    • S.H. Lee, K.J. Lee, H.J. Lee, B.J. Ham, S.H. Ryu, and M.S. Lee Association between the 5-HT6 receptor C267T polymorphism and response to antidepressant treatment in major depressive disorder Psychiatry Clin Neurosci 59 2005 140 145
    • (2005) Psychiatry Clin Neurosci , vol.59 , pp. 140-145
    • Lee, S.H.1    Lee, K.J.2    Lee, H.J.3    Ham, B.J.4    Ryu, S.H.5    Lee, M.S.6
  • 180
    • 67650087599 scopus 로고    scopus 로고
    • New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites
    • I. Lee, S.S. Ajay, J.I. Yook, H.S. Kim, S.H. Hong, and N.H. Kim et al. New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites Genome Res 19 2009 1175 1183
    • (2009) Genome Res , vol.19 , pp. 1175-1183
    • Lee, I.1    Ajay, S.S.2    Yook, J.I.3    Kim, H.S.4    Hong, S.H.5    Kim, N.H.6
  • 181
    • 77952162644 scopus 로고    scopus 로고
    • MRP1 polymorphisms associated with citalopram response in patients with major depression
    • S.H. Lee, M.S. Lee, J.H. Lee, S.W. Kim, R.H. Kang, and M.J. Choi et al. MRP1 polymorphisms associated with citalopram response in patients with major depression J Clin Psychopharmacol 30 2010 116 125
    • (2010) J Clin Psychopharmacol , vol.30 , pp. 116-125
    • Lee, S.H.1    Lee, M.S.2    Lee, J.H.3    Kim, S.W.4    Kang, R.H.5    Choi, M.J.6
  • 182
    • 44349188699 scopus 로고    scopus 로고
    • The FKBP5-gene in depression and treatment response - An association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) cohort
    • M. Lekman, G. Laje, D. Charney, A.J. Rush, A.F. Wilson, and A.J. Sorant et al. The FKBP5-gene in depression and treatment response - an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) cohort Biol Psychiatry 63 2008 1103 1110
    • (2008) Biol Psychiatry , vol.63 , pp. 1103-1110
    • Lekman, M.1    Laje, G.2    Charney, D.3    Rush, A.J.4    Wilson, A.F.5    Sorant, A.J.6
  • 184
    • 10644242682 scopus 로고    scopus 로고
    • Association of the C(-1019)G 5-HT1A functional promoter polymorphism with antidepressant response
    • DOI 10.1017/S1461145704004699
    • S. Lemonde, L. Du, D. Bakish, P. Hrdina, and P.R. Albert Association of the C(- 1019)G 5-HT1A functional promoter polymorphism with antidepressant response Int J Neuropsychopharmacol 7 2004 501 506 (Pubitemid 39648081)
    • (2004) International Journal of Neuropsychopharmacology , vol.7 , Issue.4 , pp. 501-506
    • Lemonde, S.1    Du, L.2    Bakish, D.3    Hrdina, P.4    Albert, P.R.5
  • 187
    • 48749115329 scopus 로고    scopus 로고
    • TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment
    • Y. Li, B.W. Luikart, S. Birnbaum, J. Chen, C.H. Kwon, and S.G. Kernie et al. TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment Neuron 59 2008 399 412
    • (2008) Neuron , vol.59 , pp. 399-412
    • Li, Y.1    Luikart, B.W.2    Birnbaum, S.3    Chen, J.4    Kwon, C.H.5    Kernie, S.G.6
  • 188
    • 65549105390 scopus 로고    scopus 로고
    • Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response
    • J. Licinio, C. Dong, and M.L. Wong Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response Arch Gen Psychiatry 66 2009 488 497
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 488-497
    • Licinio, J.1    Dong, C.2    Wong, M.L.3
  • 189
    • 34247526510 scopus 로고    scopus 로고
    • Tryptophan hydroxylase 2 (TPH2) haplotypes predict levels of TPH2 mRNA expression in human pons
    • DOI 10.1038/sj.mp.4001923, PII 4001923
    • J.E. Lim, J. Pinsonneault, W. Sadee, and D. Saffen Tryptophan hydroxylase 2 (TPH2) haplotypes predict levels of TPH2 mRNA expression in human pons Mol Psychiatry 12 2007 491 501 (Pubitemid 46652452)
    • (2007) Molecular Psychiatry , vol.12 , Issue.5 , pp. 491-501
    • Lim, J.-E.1    Pinsonneault, J.2    Sadee, W.3    Saffen, D.4
  • 190
    • 79955472490 scopus 로고    scopus 로고
    • ABCB1 gene polymorphisms are associated with the severity of major depressive disorder and its response to escitalopram treatment
    • K.M. Lin, Y.F. Chiu, I.J. Tsai, C.H. Chen, W.W. Shen, and S.C. Liu et al. ABCB1 gene polymorphisms are associated with the severity of major depressive disorder and its response to escitalopram treatment Pharmacogenet Genomics 21 2011 163 170
    • (2011) Pharmacogenet Genomics , vol.21 , pp. 163-170
    • Lin, K.M.1    Chiu, Y.F.2    Tsai, I.J.3    Chen, C.H.4    Shen, W.W.5    Liu, S.C.6
  • 191
    • 57449096759 scopus 로고    scopus 로고
    • Steady-state concentrations of mirtazapine, N-desmethylmirtazapine, 8-hydroxymirtazapine and their enantiomers in relation to cytochrome P450 2D6 genotype, age and smoking behaviour
    • A.B. Lind, M. Reis, F. Bengtsson, M. Jonzier-Perey, K. Powell Golay, and J. Ahlner et al. Steady-state concentrations of mirtazapine, N-desmethylmirtazapine, 8-hydroxymirtazapine and their enantiomers in relation to cytochrome P450 2D6 genotype, age and smoking behaviour Clin Pharmacokinet 48 2009 63 70
    • (2009) Clin Pharmacokinet , vol.48 , pp. 63-70
    • Lind, A.B.1    Reis, M.2    Bengtsson, F.3    Jonzier-Perey, M.4    Powell Golay, K.5    Ahlner, J.6
  • 192
    • 80054106740 scopus 로고    scopus 로고
    • The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf(+)/(-) heterozygous null mice
    • J.S. Lindholm, H. Autio, L. Vesa, H. Antila, L. Lindemann, and M.C. Hoener et al. The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf(+)/(-) heterozygous null mice Neuropharmacology 62 2012 391 397
    • (2012) Neuropharmacology , vol.62 , pp. 391-397
    • Lindholm, J.S.1    Autio, H.2    Vesa, L.3    Antila, H.4    Lindemann, L.5    Hoener, M.C.6
  • 193
    • 70349575487 scopus 로고    scopus 로고
    • Support for the involvement of the KCNK2 gene in major depressive disorder and response to antidepressant treatment
    • Y.J. Liou, T.J. Chen, S.J. Tsai, Y.W. Yu, C.Y. Cheng, and C.J. Hong Support for the involvement of the KCNK2 gene in major depressive disorder and response to antidepressant treatment Pharmacogenet Genomics 19 2009 735 741
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 735-741
    • Liou, Y.J.1    Chen, T.J.2    Tsai, S.J.3    Yu, Y.W.4    Cheng, C.Y.5    Hong, C.J.6
  • 195
    • 0034818768 scopus 로고    scopus 로고
    • Effect of the CYP2C19 oxidation polymorphism on fluoxetine metabolism in Chinese healthy subjects
    • Z.Q. Liu, Z.N. Cheng, S.L. Huang, X.P. Chen, D.S. Ou-Yang, and C.H. Jiang et al. Effect of the CYP2C19 oxidation polymorphism on fluoxetine metabolism in Chinese healthy subjects Br J Clin Pharmacol 52 2001 96 99
    • (2001) Br J Clin Pharmacol , vol.52 , pp. 96-99
    • Liu, Z.Q.1    Cheng, Z.N.2    Huang, S.L.3    Chen, X.P.4    Ou-Yang, D.S.5    Jiang, C.H.6
  • 196
    • 84857083262 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex
    • R.J. Liu, F.S. Lee, X.Y. Li, F. Bambico, R.S. Duman, and G.K. Aghajanian Brain-derived neurotrophic factor Val66Met allele impairs basal and ketamine-stimulated synaptogenesis in prefrontal cortex Biol Psychiatry 71 2012 996 1005
    • (2012) Biol Psychiatry , vol.71 , pp. 996-1005
    • Liu, R.J.1    Lee, F.S.2    Li, X.Y.3    Bambico, F.4    Duman, R.S.5    Aghajanian, G.K.6
  • 197
    • 1542620667 scopus 로고    scopus 로고
    • Effect of CYP2D6 and CYP2C9 genotypes on fluoxetine and norfluoxetine plasma concentrations during steady-state conditions
    • DOI 10.1007/s00228-003-0707-y
    • A. Llerena, P. Dorado, R. Berecz, A.P. Gonzalez, and L.E.M. Penas Effect of CYP2D6 and CYP2C9 genotypes on fluoxetine and norfluoxetine plasma concentrations during steady-state conditions Eur J Clin Pharmacol 59 2004 869 873 (Pubitemid 38337438)
    • (2004) European Journal of Clinical Pharmacology , vol.59 , Issue.12 , pp. 869-873
    • Llerena, A.1    Dorado, P.2    Berecz, R.3    Gonzalez, A.P.4    Penas, L.E.M.5
  • 198
    • 84861592655 scopus 로고    scopus 로고
    • Potential utility of optogenetics in the study of depression
    • M.K. Lobo, E.J. Nestler, and H.E. Covington III Potential utility of optogenetics in the study of depression Biol Psychiatry 71 2012 1068 1074
    • (2012) Biol Psychiatry , vol.71 , pp. 1068-1074
    • Lobo, M.K.1    Nestler, E.J.2    Covington III, H.E.3
  • 199
    • 0037270399 scopus 로고    scopus 로고
    • The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit
    • DOI 10.1046/j.1460-9568.2003.02446.x
    • E.A. Lovejoy, A.C. Scott, C.E. Fiskerstrand, V.J. Bubb, and J.P. Quinn The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit Eur J Neurosci 17 2003 417 420 (Pubitemid 36459521)
    • (2003) European Journal of Neuroscience , vol.17 , Issue.2 , pp. 417-420
    • Lovejoy, E.A.1    Scott, A.C.2    Fiskerstrand, C.E.3    Bubb, V.J.4    Quinn, J.P.5
  • 200
    • 23044488902 scopus 로고    scopus 로고
    • The yin and yang of neurotrophin action
    • DOI 10.1038/nrn1726
    • B. Lu, P.T. Pang, and N.H. Woo The yin and yang of neurotrophin action Nat Rev Neurosci 6 2005 603 614 (Pubitemid 41059335)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.8 , pp. 603-614
    • Lu, B.1    Pang, P.T.2    Woo, N.H.3
  • 203
    • 2142822258 scopus 로고    scopus 로고
    • Distinguishing roles for norepinephrine and serotonin in the behavioral effects of antidepressant drugs
    • I. Lucki, and O.F. O'Leary Distinguishing roles for norepinephrine and serotonin in the behavioral effects of antidepressant drugs J Clin Psychiatry 65 Suppl. 4 2004 11 24
    • (2004) J Clin Psychiatry , vol.65 , Issue.SUPPL. 4 , pp. 11-24
    • Lucki, I.1    O'Leary, O.F.2
  • 204
    • 0033593033 scopus 로고    scopus 로고
    • A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo
    • DOI 10.1073/pnas.96.26.15251
    • A. MacKenzie, and J. Quinn A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo Proc Natl Acad Sci U S A 96 1999 15251 15255 (Pubitemid 30019798)
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.26 , pp. 15251-15255
    • MacKenzie, A.1    Quinn, J.2
  • 207
    • 0037123808 scopus 로고    scopus 로고
    • 1B receptor knock-out mice
    • DOI 10.1016/S0014-2999(02)01604-7, PII S0014299902016047
    • I. Malagie, D.J. David, P. Jolliet, R. Hen, M. Bourin, and A.M. Gardier Improved efficacy of fluoxetine in increasing hippocampal 5-hydroxytryptamine outflow in 5-HT(1B) receptor knock-out mice Eur J Pharmacol 443 2002 99 104 (Pubitemid 34603603)
    • (2002) European Journal of Pharmacology , vol.443 , Issue.1-3 , pp. 99-104
    • Malagie, I.1    David, D.J.2    Jolliet, P.3    Hen, R.4    Bourin, M.5    Gardier, A.M.6
  • 208
    • 79959963903 scopus 로고    scopus 로고
    • Role of COMT, 5-HT(1A), and SERT genetic polymorphisms on antidepressant response to transcranial magnetic stimulation
    • A. Malaguti, D. Rossini, A. Lucca, L. Magri, C. Lorenzi, and A. Pirovano et al. Role of COMT, 5-HT(1A), and SERT genetic polymorphisms on antidepressant response to transcranial magnetic stimulation Depress Anxiety 28 2011 568 573
    • (2011) Depress Anxiety , vol.28 , pp. 568-573
    • Malaguti, A.1    Rossini, D.2    Lucca, A.3    Magri, L.4    Lorenzi, C.5    Pirovano, A.6
  • 209
    • 33645316100 scopus 로고    scopus 로고
    • The norepinephrine transporter and its regulation
    • P. Mandela, and G.A. Ordway The norepinephrine transporter and its regulation J Neurochem 97 2006 310 333
    • (2006) J Neurochem , vol.97 , pp. 310-333
    • Mandela, P.1    Ordway, G.A.2
  • 210
    • 65049084627 scopus 로고    scopus 로고
    • Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression
    • E. Maron, A. Tammiste, K. Kallassalu, T. Eller, V. Vasar, and D.J. Nutt et al. Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression Eur Neuropsychopharmacol 19 2009 451 456
    • (2009) Eur Neuropsychopharmacol , vol.19 , pp. 451-456
    • Maron, E.1    Tammiste, A.2    Kallassalu, K.3    Eller, T.4    Vasar, V.5    Nutt, D.J.6
  • 211
    • 1642523162 scopus 로고    scopus 로고
    • Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
    • DOI 10.1016/j.clpt.2003.09.012
    • C. Marzolini, E. Paus, T. Buclin, and R.B. Kim Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance Clin Pharmacol Ther 75 2004 13 33 (Pubitemid 38130115)
    • (2004) Clinical Pharmacology and Therapeutics , vol.75 , Issue.1 , pp. 13-33
    • Marzolini, C.1    Paus, E.2    Buclin, T.3    Kim, R.B.4
  • 212
    • 84867685385 scopus 로고    scopus 로고
    • Changes in the brain accumulation of glucocorticoids in abcb1a-deficient CF-1 mice
    • B.L. Mason, C.M. Pariante, and S.A. Thomas Changes in the brain accumulation of glucocorticoids in abcb1a-deficient CF-1 mice J Neuroendocrinol 24 2012 1440 1446
    • (2012) J Neuroendocrinol , vol.24 , pp. 1440-1446
    • Mason, B.L.1    Pariante, C.M.2    Thomas, S.A.3
  • 214
    • 33646062299 scopus 로고    scopus 로고
    • Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment
    • F.J. McMahon, S. Buervenich, D. Charney, R. Lipsky, A.J. Rush, and A.F. Wilson et al. Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment Am J Hum Genet 78 2006 804 814
    • (2006) Am J Hum Genet , vol.78 , pp. 804-814
    • McMahon, F.J.1    Buervenich, S.2    Charney, D.3    Lipsky, R.4    Rush, A.J.5    Wilson, A.F.6
  • 216
    • 84867709301 scopus 로고    scopus 로고
    • Epigenetics, depression and antidepressant treatment
    • A. Menke, T. Klengel, and E.B. Binder Epigenetics, depression and antidepressant treatment Curr Pharm Des 18 2012 5879 5889
    • (2012) Curr Pharm des , vol.18 , pp. 5879-5889
    • Menke, A.1    Klengel, T.2    Binder, E.B.3
  • 218
    • 67650999148 scopus 로고    scopus 로고
    • Monoamine transporter gene polymorphisms affect susceptibility to depression and predict antidepressant response
    • W. Min, T. Li, X. Ma, Z. Li, T. Yu, and D. Gao et al. Monoamine transporter gene polymorphisms affect susceptibility to depression and predict antidepressant response Psychopharmacology (Berl) 205 2009 409 417
    • (2009) Psychopharmacology (Berl) , vol.205 , pp. 409-417
    • Min, W.1    Li, T.2    Ma, X.3    Li, Z.4    Yu, T.5    Gao, D.6
  • 219
    • 0035805390 scopus 로고    scopus 로고
    • Serotonin-2A-receptor and -transporter polymorphisms: Lack of association in patients with major depression
    • DOI 10.1016/S0304-3940(01)01704-9, PII S0304394001017049
    • C. Minov, T.C. Baghai, C. Schule, P. Zwanzger, M.J. Schwarz, and P. Zill et al. Serotonin-2A-receptor and -transporter polymorphisms: lack of association in patients with major depression Neurosci Lett 303 2001 119 122 (Pubitemid 32320019)
    • (2001) Neuroscience Letters , vol.303 , Issue.2 , pp. 119-122
    • Minov, C.1    Baghai, T.C.2    Schule, C.3    Zwanzger, P.4    Schwarz, M.J.5    Zill, P.6    Rupprecht, R.7    Bondy, B.8
  • 222
    • 33846105118 scopus 로고    scopus 로고
    • Brain-Derived Neurotrophic Factor Conditional Knockouts Show Gender Differences in Depression-Related Behaviors
    • DOI 10.1016/j.biopsych.2006.03.021, PII S0006322306003970
    • L.M. Monteggia, B. Luikart, M. Barrot, D. Theobold, I. Malkovska, and S. Nef et al. Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors Biol Psychiatry 61 2007 187 197 (Pubitemid 46072778)
    • (2007) Biological Psychiatry , vol.61 , Issue.2 , pp. 187-197
    • Monteggia, L.M.1    Luikart, B.2    Barrot, M.3    Theobold, D.4    Malkovska, I.5    Nef, S.6    Parada, L.F.7    Nestler, E.J.8
  • 224
    • 0034115770 scopus 로고    scopus 로고
    • Steady-state plasma levels of nortriptyline and its hydroxylated metabolites in Japanese patients: Impact of CYP2D6 genotype on the hydroxylation of nortriptyline
    • DOI 10.1097/00004714-200004000-00005
    • S. Morita, K. Shimoda, T. Someya, Y. Yoshimura, K. Kamijima, and N. Kato Steady-state plasma levels of nortriptyline and its hydroxylated metabolites in Japanese patients: impact of CYP2D6 genotype on the hydroxylation of nortriptyline J Clin Psychopharmacol 20 2000 141 149 (Pubitemid 30202355)
    • (2000) Journal of Clinical Psychopharmacology , vol.20 , Issue.2 , pp. 141-149
    • Morita, S.1    Shimoda, K.2    Someya, T.3    Yoshimura, Y.4    Kamijima, K.5    Kato, N.6
  • 225
  • 227
    • 33644621556 scopus 로고    scopus 로고
    • The impact of cytochrome P450-2D6 genotype on the use and interpretation of therapeutic drug monitoring in long-stay patients treated with antidepressant and antipsychotic drugs in daily psychiatric practice
    • H. Mulder, A. Herder, F.W. Wilmink, W.J. Tamminga, S.V. Belitser, and A.C. Egberts The impact of cytochrome P450-2D6 genotype on the use and interpretation of therapeutic drug monitoring in long-stay patients treated with antidepressant and antipsychotic drugs in daily psychiatric practice Pharmacoepidemiol Drug Saf 15 2006 107 114
    • (2006) Pharmacoepidemiol Drug Saf , vol.15 , pp. 107-114
    • Mulder, H.1    Herder, A.2    Wilmink, F.W.3    Tamminga, W.J.4    Belitser, S.V.5    Egberts, A.C.6
  • 228
    • 84886252097 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressants, mood stabilizers, and antipsychotics in diverse human populations
    • E. Murphy, and F.J. McMahon Pharmacogenetics of antidepressants, mood stabilizers, and antipsychotics in diverse human populations Discov Med 16 2013 113 122
    • (2013) Discov Med , vol.16 , pp. 113-122
    • Murphy, E.1    McMahon, F.J.2
  • 230
    • 2342629856 scopus 로고    scopus 로고
    • Serotonin transporter: Gene, genetic disorders, and pharmacogenetics
    • DOI 10.1124/mi.4.2.8
    • D.L. Murphy, A. Lerner, G. Rudnick, and K.P. Lesch Serotonin transporter: gene, genetic disorders, and pharmacogenetics Mol Interv 4 2004 109 123 (Pubitemid 38584973)
    • (2004) Molecular Interventions , vol.4 , Issue.2 , pp. 109-123
    • Murphy, D.L.1    Lerner, A.2    Rudnick, G.3    Lesch, K.-P.4
  • 231
    • 77953287640 scopus 로고    scopus 로고
    • Serotonin transporter polymorphisms (SLC6A4 insertion/deletion and rs25531) do not affect the availability of 5-HTT to [11C] DASB binding in the living human brain
    • N.V. Murthy, S. Selvaraj, P.J. Cowen, Z. Bhagwagar, W.J. Riedel, and P. Peers et al. Serotonin transporter polymorphisms (SLC6A4 insertion/deletion and rs25531) do not affect the availability of 5-HTT to [11C] DASB binding in the living human brain Neuroimage 52 2010 50 54
    • (2010) Neuroimage , vol.52 , pp. 50-54
    • Murthy, N.V.1    Selvaraj, S.2    Cowen, P.J.3    Bhagwagar, Z.4    Riedel, W.J.5    Peers, P.6
  • 232
    • 84878408522 scopus 로고    scopus 로고
    • The action of antidepressants on the glutamate system: Regulation of glutamate release and glutamate receptors
    • L. Musazzi, G. Treccani, A. Mallei, and M. Popoli The action of antidepressants on the glutamate system: regulation of glutamate release and glutamate receptors Biological psychiatry 73 2013 1180 1188
    • (2013) Biological Psychiatry , vol.73 , pp. 1180-1188
    • Musazzi, L.1    Treccani, G.2    Mallei, A.3    Popoli, M.4
  • 234
    • 84857717326 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressant drugs: Current clinical practice and future directions
    • S. Narasimhan, and F.W. Lohoff Pharmacogenetics of antidepressant drugs: current clinical practice and future directions Pharmacogenomics 13 2012 441 464
    • (2012) Pharmacogenomics , vol.13 , pp. 441-464
    • Narasimhan, S.1    Lohoff, F.W.2
  • 235
    • 0028950497 scopus 로고
    • Desipramine treatment of major depression in patients over 75 years of age
    • J.C. Nelson, C.M. Mazure, and P.I. Jatlow Desipramine treatment of major depression in patients over 75 years of age J Clin Psychopharmacol 15 1995 99 105
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 99-105
    • Nelson, J.C.1    Mazure, C.M.2    Jatlow, P.I.3
  • 236
    • 33746900423 scopus 로고    scopus 로고
    • The Mesolimbic Dopamine Reward Circuit in Depression
    • DOI 10.1016/j.biopsych.2005.09.018, PII S0006322305012436
    • E.J. Nestler, and W.A. Carlezon Jr. The mesolimbic dopamine reward circuit in depression Biol Psychiatry 59 2006 1151 1159 (Pubitemid 44192421)
    • (2006) Biological Psychiatry , vol.59 , Issue.12 , pp. 1151-1159
    • Nestler, E.J.1    Carlezon Jr., W.A.2
  • 238
    • 56949103059 scopus 로고    scopus 로고
    • Citalopram enantiomers in plasma and cerebrospinal fluid of ABCB1 genotyped depressive patients and clinical response: A pilot study
    • G. Nikisch, C.B. Eap, and P. Baumann Citalopram enantiomers in plasma and cerebrospinal fluid of ABCB1 genotyped depressive patients and clinical response: a pilot study Pharmacol Res 58 2008 344 347
    • (2008) Pharmacol Res , vol.58 , pp. 344-347
    • Nikisch, G.1    Eap, C.B.2    Baumann, P.3
  • 239
    • 2542463283 scopus 로고    scopus 로고
    • Paroxetine in major depression: Correlating plasma concentrations and clinical response
    • DOI 10.1055/s-2004-818990
    • C. Normann, M. Horn, B. Hummel, H. Grunze, and J. Walden Paroxetine in major depression: correlating plasma concentrations and clinical response Pharmacopsychiatry 37 2004 123 126 (Pubitemid 38680333)
    • (2004) Pharmacopsychiatry , vol.37 , Issue.3 , pp. 123-126
    • Normann, C.1    Horn, M.2    Hummel, B.3    Grunze, H.4    Walden, J.5
  • 240
    • 3142615372 scopus 로고    scopus 로고
    • The RNAi revolution
    • DOI 10.1038/430161a
    • C.D. Novina, and P.A. Sharp The RNAi revolution Nature 430 2004 161 164 (Pubitemid 38902417)
    • (2004) Nature , vol.430 , Issue.6996 , pp. 161-164
    • Novina, C.D.1    Sharp, P.A.2
  • 241
    • 84861306227 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: Microdialysis studies in conscious freely moving rats
    • F.E. O'Brien, G. Clarke, P. Fitzgerald, T.G. Dinan, B.T. Griffin, and J.F. Cryan Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats Br J Pharmacol 166 2012 1333 1343
    • (2012) Br J Pharmacol , vol.166 , pp. 1333-1343
    • O'Brien, F.E.1    Clarke, G.2    Fitzgerald, P.3    Dinan, T.G.4    Griffin, B.T.5    Cryan, J.F.6
  • 242
    • 83755205460 scopus 로고    scopus 로고
    • Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: Clinical significance of in vitro and in vivo findings
    • F.E. O'Brien, T.G. Dinan, B.T. Griffin, and J.F. Cryan Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: clinical significance of in vitro and in vivo findings Br J Pharmacol 165 2012 289 312
    • (2012) Br J Pharmacol , vol.165 , pp. 289-312
    • O'Brien, F.E.1    Dinan, T.G.2    Griffin, B.T.3    Cryan, J.F.4
  • 243
    • 84884222342 scopus 로고    scopus 로고
    • P-glycoprotein inhibition increases the brain distribution and antidepressant-like activity of escitalopram in rodents
    • F.E. O'Brien, R.M. O'Connor, G. Clarke, T.G. Dinan, B.T. Griffin, and J.F. Cryan P-glycoprotein inhibition increases the brain distribution and antidepressant-like activity of escitalopram in rodents Neuropsychopharmacology 38 2013 2209 2219
    • (2013) Neuropsychopharmacology , vol.38 , pp. 2209-2219
    • O'Brien, F.E.1    O'Connor, R.M.2    Clarke, G.3    Dinan, T.G.4    Griffin, B.T.5    Cryan, J.F.6
  • 244
    • 84884220655 scopus 로고    scopus 로고
    • Human P-glycoprotein differentially affects antidepressant drug transport: Relevance to blood-brain barrier permeability
    • F.E. O'Brien, G. Clarke, T.G. Dinan, J.F. Cryan, and B.T. Griffin Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability Int J Neuropsychopharmacol 2013 1 14
    • (2013) Int J Neuropsychopharmacol , pp. 1-14
    • O'Brien, F.E.1    Clarke, G.2    Dinan, T.G.3    Cryan, J.F.4    Griffin, B.T.5
  • 245
    • 77953672168 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 7: At the interface of cognition and emotion
    • R.M. O'Connor, B.C. Finger, P.J. Flor, and J.F. Cryan Metabotropic glutamate receptor 7: at the interface of cognition and emotion Eur J Pharmacol 639 2010 123 131
    • (2010) Eur J Pharmacol , vol.639 , pp. 123-131
    • O'Connor, R.M.1    Finger, B.C.2    Flor, P.J.3    Cryan, J.F.4
  • 246
    • 84859005549 scopus 로고    scopus 로고
    • Little things on which happiness depends: MicroRNAs as novel therapeutic targets for the treatment of anxiety and depression
    • R.M. O'Connor, T.G. Dinan, and J.F. Cryan Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression Mol Psychiatry 17 2012 359 376
    • (2012) Mol Psychiatry , vol.17 , pp. 359-376
    • O'Connor, R.M.1    Dinan, T.G.2    Cryan, J.F.3
  • 247
    • 84882939097 scopus 로고    scopus 로고
    • MicroRNAs as novel antidepressant targets: Converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus
    • R.M. O'Connor, S. Grenham, T.G. Dinan, and J.F. Cryan microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus The international journal of neuropsychopharmacology 16 2013 1885 1892
    • (2013) The International Journal of Neuropsychopharmacology , vol.16 , pp. 1885-1892
    • O'Connor, R.M.1    Grenham, S.2    Dinan, T.G.3    Cryan, J.F.4
  • 248
    • 80054095327 scopus 로고    scopus 로고
    • Neurotrophic factors and antidepressant action: Recent advances
    • J.F. Cryan, B.E. Leonard, Karger Basel
    • O.F. O'Leary, and E. Castren Neurotrophic factors and antidepressant action: Recent advances J.F. Cryan, B.E. Leonard, Depression: from psychopathology to pharmacotherapy 2010 Karger Basel 199 223
    • (2010) Depression: From Psychopathology to Pharmacotherapy , pp. 199-223
    • O'Leary, O.F.1    Castren, E.2
  • 249
    • 70349838040 scopus 로고    scopus 로고
    • The tail suspension test: A model for characterizing antidepressant activity in mice
    • T. Gould, Springer USA
    • O.F. O'Leary, and J.F. Cryan The tail suspension test: a model for characterizing antidepressant activity in mice T. Gould, Mood & anxiety related phenotypes in mice 2009 Springer USA 119 137
    • (2009) Mood & Anxiety Related Phenotypes in Mice , pp. 119-137
    • O'Leary, O.F.1    Cryan, J.F.2
  • 250
    • 79251593587 scopus 로고    scopus 로고
    • The behavioural genetics of serotonin: Relevance to anxiety and depression
    • C.P. Muller, B.L. Jacobs, Academic Press USA
    • O.F. O'Leary, and J.F. Cryan The behavioural genetics of serotonin: relevance to anxiety and depression C.P. Muller, B.L. Jacobs, Handbook of the behavioral neurobiology of serotonin 2010 Academic Press USA 749 791
    • (2010) Handbook of the Behavioral Neurobiology of Serotonin , pp. 749-791
    • O'Leary, O.F.1    Cryan, J.F.2
  • 251
    • 84885581328 scopus 로고    scopus 로고
    • Towards translational rodent models of depression
    • O.F. O'Leary, and J.F. Cryan Towards translational rodent models of depression Cell Tissue Res 354 1 2013 141 153
    • (2013) Cell Tissue Res , vol.354 , Issue.1 , pp. 141-153
    • O'Leary, O.F.1    Cryan, J.F.2
  • 252
    • 34247872922 scopus 로고    scopus 로고
    • Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test
    • DOI 10.1007/s00213-007-0728-9
    • O.F. O'Leary, A.J. Bechtholt, J.J. Crowley, T.E. Hill, M.E. Page, and I. Lucki Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test Psychopharmacology (Berl) 192 2007 357 371 (Pubitemid 46701581)
    • (2007) Psychopharmacology , vol.192 , Issue.3 , pp. 357-371
    • O'Leary, O.F.1    Bechtholt, A.J.2    Crowley, J.J.3    Hill, T.E.4    Page, M.E.5    Lucki, I.6
  • 253
    • 59249099507 scopus 로고    scopus 로고
    • Chronic fluoxetine treatment increases expression of synaptic proteins in the hippocampus of the ovariectomized rat: Role of BDNF signalling
    • O.F. O'Leary, X. Wu, and E. Castren Chronic fluoxetine treatment increases expression of synaptic proteins in the hippocampus of the ovariectomized rat: role of BDNF signalling Psychoneuroendocrinology 34 2009 367 381
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 367-381
    • O'Leary, O.F.1    Wu, X.2    Castren, E.3
  • 254
    • 84868520727 scopus 로고    scopus 로고
    • Lithium augmentation of the effects of desipramine in a mouse model of treatment-resistant depression: A role for hippocampal cell proliferation
    • O.F. O'Leary, S. Zandy, T.G. Dinan, and J.F. Cryan Lithium augmentation of the effects of desipramine in a mouse model of treatment-resistant depression: a role for hippocampal cell proliferation Neuroscience 228 2013 36 46
    • (2013) Neuroscience , vol.228 , pp. 36-46
    • O'Leary, O.F.1    Zandy, S.2    Dinan, T.G.3    Cryan, J.F.4
  • 255
    • 40949084721 scopus 로고    scopus 로고
    • A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders
    • J.D. Olivier, M.G. Van Der Hart, R.P. Van Swelm, P.J. Dederen, J.R. Homberg, and T. Cremers et al. A study in male and female 5-HT transporter knockout rats: an animal model for anxiety and depression disorders Neuroscience 152 2008 573 584
    • (2008) Neuroscience , vol.152 , pp. 573-584
    • Olivier, J.D.1    Van Der Hart, M.G.2    Van Swelm, R.P.3    Dederen, P.J.4    Homberg, J.R.5    Cremers, T.6
  • 258
    • 84980053687 scopus 로고    scopus 로고
    • Influence of BDNF variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia
    • C.U. Pae, A. Chiesa, S. Porcelli, C. Han, A.A. Patkar, and S.J. Lee et al. Influence of BDNF variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia Neuropsychobiology 65 2012 1 11
    • (2012) Neuropsychobiology , vol.65 , pp. 1-11
    • Pae, C.U.1    Chiesa, A.2    Porcelli, S.3    Han, C.4    Patkar, A.A.5    Lee, S.J.6
  • 259
    • 0033220002 scopus 로고    scopus 로고
    • Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test
    • M.E. Page, M.J. Detke, A. Dalvi, L.G. Kirby, and I. Lucki Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test Psychopharmacology (Berl) 147 1999 162 167 (Pubitemid 30010563)
    • (1999) Psychopharmacology , vol.147 , Issue.2 , pp. 162-167
    • Page, M.E.1    Detke, M.J.2    Dalvi, A.3    Kirby, L.G.4    Lucki, I.5
  • 260
    • 0034991368 scopus 로고    scopus 로고
    • Animal models of anxiety and depression: How are females different?
    • DOI 10.1016/S0149-7634(01)00010-0, PII S0149763401000100
    • P. Palanza Animal models of anxiety and depression: how are females different? Neurosci Biobehav Rev 25 2001 219 233 (Pubitemid 32506875)
    • (2001) Neuroscience and Biobehavioral Reviews , vol.25 , Issue.3 , pp. 219-233
    • Palanza, P.1
  • 261
    • 70349268327 scopus 로고    scopus 로고
    • MicroRNAs regulate CYP3A4 expression via direct and indirect targeting
    • Y.Z. Pan, W. Gao, and A.M. Yu MicroRNAs regulate CYP3A4 expression via direct and indirect targeting Drug Metab Dispos 37 2009 2112 2117
    • (2009) Drug Metab Dispos , vol.37 , pp. 2112-2117
    • Pan, Y.Z.1    Gao, W.2    Yu, A.M.3
  • 262
    • 84861022548 scopus 로고    scopus 로고
    • Modulation of neuroplasticity pathways and antidepressant-like behavioural responses following the short-term (3 and 7 days) administration of the 5-HT(4) receptor agonist RS67333
    • J. Pascual-Brazo, E. Castro, A. Diaz, E.M. Valdizan, F. Pilar-Cuellar, and R. Vidal et al. Modulation of neuroplasticity pathways and antidepressant-like behavioural responses following the short-term (3 and 7 days) administration of the 5-HT(4) receptor agonist RS67333 Int J Neuropsychopharmacol 15 2012 631 643
    • (2012) Int J Neuropsychopharmacol , vol.15 , pp. 631-643
    • Pascual-Brazo, J.1    Castro, E.2    Diaz, A.3    Valdizan, E.M.4    Pilar-Cuellar, F.5    Vidal, R.6
  • 263
    • 36849005953 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Its mechanism and its modulation
    • DOI 10.1358/dnp.2007.20.6.1141496
    • E.K.J. Pauwels, P. Erba, G. Mariani, and C.M.F. Gomes Multidrug resistance in cancer: its mechanism and its modulation Drug News Perspect 20 2007 371 377 (Pubitemid 350219069)
    • (2007) Drug News and Perspectives , vol.20 , Issue.6 , pp. 371-377
    • Pauwels, E.K.J.1    Erba, P.2    Mariani, G.3    Gomes, C.M.F.4
  • 265
    • 50249189084 scopus 로고    scopus 로고
    • Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: Association of TREK1 and treatment resistance in the STAR(*)D study
    • R.H. Perlis, P. Moorjani, J. Fagerness, S. Purcell, M.H. Trivedi, and M. Fava et al. Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study Neuropsychopharmacology 33 2008 2810 2819
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2810-2819
    • Perlis, R.H.1    Moorjani, P.2    Fagerness, J.3    Purcell, S.4    Trivedi, M.H.5    Fava, M.6
  • 266
    • 63449087185 scopus 로고    scopus 로고
    • Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder
    • R.H. Perlis, B. Fijal, D.H. Adams, V.K. Sutton, M.H. Trivedi, and J.P. Houston Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder Biol Psychiatry 65 2009 785 791
    • (2009) Biol Psychiatry , vol.65 , pp. 785-791
    • Perlis, R.H.1    Fijal, B.2    Adams, D.H.3    Sutton, V.K.4    Trivedi, M.H.5    Houston, J.P.6
  • 267
    • 77951880638 scopus 로고    scopus 로고
    • Failure to replicate genetic associations with antidepressant treatment response in duloxetine-treated patients
    • R.H. Perlis, B. Fijal, S. Dharia, A.N. Heinloth, and J.P. Houston Failure to replicate genetic associations with antidepressant treatment response in duloxetine-treated patients Biol Psychiatry 67 2010 1110 1113
    • (2010) Biol Psychiatry , vol.67 , pp. 1110-1113
    • Perlis, R.H.1    Fijal, B.2    Dharia, S.3    Heinloth, A.N.4    Houston, J.P.5
  • 268
    • 27844539882 scopus 로고    scopus 로고
    • Antipanic efficacy of paroxetine and polymorphism within the promoter of the serotonin transporter gene
    • DOI 10.1038/sj.npp.1300822, PII 1300822
    • G. Perna, E. Favaron, D. Di Bella, R. Bussi, and L. Bellodi Antipanic efficacy of paroxetine and polymorphism within the promoter of the serotonin transporter gene Neuropsychopharmacology 30 2005 2230 2235 (Pubitemid 41643974)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.12 , pp. 2230-2235
    • Perna, G.1    Favaron, E.2    Di Bella, D.3    Bussi, R.4    Bellodi, L.5
  • 269
    • 57649166962 scopus 로고    scopus 로고
    • Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: Prominent effects of dopamine transporter deletions
    • M.T. Perona, S. Waters, F.S. Hall, I. Sora, K.P. Lesch, and D.L. Murphy et al. Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions Behav Pharmacol 19 2008 566 574
    • (2008) Behav Pharmacol , vol.19 , pp. 566-574
    • Perona, M.T.1    Waters, S.2    Hall, F.S.3    Sora, I.4    Lesch, K.P.5    Murphy, D.L.6
  • 270
    • 0023606125 scopus 로고
    • The relationship between antidepressant response and tricyclic andidepressant plasma concentrations. A retrospective analysis of the literature using logistic regression analysis
    • P.J. Perry, B.M. Pfohl, and S.G. Holstad The relationship between antidepressant response and tricyclic antidepressant plasma concentrations. A retrospective analysis of the literature using logistic regression analysis Clin Pharmacokinet 13 1987 381 392 (Pubitemid 18018786)
    • (1987) Clinical Pharmacokinetics , vol.13 , Issue.6 , pp. 381-392
    • Perry, P.J.1    Pfohl, B.M.2    Holstad, S.G.3
  • 271
    • 4644303054 scopus 로고    scopus 로고
    • Investigation of serotonin-related genes in antidepressant response
    • DOI 10.1038/sj.mp.4001502
    • E.J. Peters, S.L. Slager, P.J. McGrath, J.A. Knowles, and S.P. Hamilton Investigation of serotonin-related genes in antidepressant response Mol Psychiatry 9 2004 879 889 (Pubitemid 39273536)
    • (2004) Molecular Psychiatry , vol.9 , Issue.9 , pp. 879-889
    • Peters, E.J.1    Slager, S.L.2    McGrath, P.J.3    Knowles, J.A.4    Hamilton, S.P.5
  • 272
  • 275
    • 0033807374 scopus 로고    scopus 로고
    • Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression
    • B.G. Pollock, R.E. Ferrell, B.H. Mulsant, S. Mazumdar, M. Miller, and R.A. Sweet et al. Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression Neuropsychopharmacology 23 2000 587 590
    • (2000) Neuropsychopharmacology , vol.23 , pp. 587-590
    • Pollock, B.G.1    Ferrell, R.E.2    Mulsant, B.H.3    Mazumdar, S.4    Miller, M.5    Sweet, R.A.6
  • 278
    • 84857236103 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy
    • S. Porcelli, C. Fabbri, and A. Serretti Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy Eur Neuropsychopharmacol 22 2012 239 258
    • (2012) Eur Neuropsychopharmacol , vol.22 , pp. 239-258
    • Porcelli, S.1    Fabbri, C.2    Serretti, A.3
  • 279
    • 84862906610 scopus 로고    scopus 로고
    • Role of CNS efflux drug transporters in antiepileptic drug delivery: Overcoming CNS efflux drug transport
    • H. Potschka Role of CNS efflux drug transporters in antiepileptic drug delivery: overcoming CNS efflux drug transport Adv Drug Deliv Rev 64 2012 943 952
    • (2012) Adv Drug Deliv Rev , vol.64 , pp. 943-952
    • Potschka, H.1
  • 280
    • 84879563161 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 phenoconversion is common in patients being treated for depression: Implications for personalized medicine
    • S.H. Preskorn, C.P. Kane, K. Lobello, A.I. Nichols, R. Fayyad, and G. Buckley et al. Cytochrome P450 2D6 phenoconversion is common in patients being treated for depression: implications for personalized medicine J Clin Psychiatry 74 6 2013 614 621
    • (2013) J Clin Psychiatry , vol.74 , Issue.6 , pp. 614-621
    • Preskorn, S.H.1    Kane, C.P.2    Lobello, K.3    Nichols, A.I.4    Fayyad, R.5    Buckley, G.6
  • 281
    • 34547499702 scopus 로고    scopus 로고
    • Dissecting the human BDNF locus: Bidirectional transcription, complex splicing, and multiple promoters
    • DOI 10.1016/j.ygeno.2007.05.004, PII S0888754307001188
    • P. Pruunsild, A. Kazantseva, T. Aid, K. Palm, and T. Timmusk Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters Genomics 90 2007 397 406 (Pubitemid 47179877)
    • (2007) Genomics , vol.90 , Issue.3 , pp. 397-406
    • Pruunsild, P.1    Kazantseval, A.2    Aid, T.3    Palm, K.4    Timmusk, T.5
  • 285
    • 0036569623 scopus 로고    scopus 로고
    • Initial conditions of serotonin transporter kinetics and genotype: Influence on SSRI treatment trial outcome
    • DOI 10.1016/S0006-3223(01)01283-5, PII S0006322301012835
    • J.L. Rausch, M.E. Johnson, Y.J. Fei, J.Q. Li, N. Shendarkar, and H.M. Hobby et al. Initial conditions of serotonin transporter kinetics and genotype: influence on SSRI treatment trial outcome Biol Psychiatry 51 2002 723 732 (Pubitemid 34450808)
    • (2002) Biological Psychiatry , vol.51 , Issue.9 , pp. 723-732
    • Rausch, J.L.1    Johnson, M.E.2    Fei, Y.-J.3    Li, J.Q.4    Shendarkar, N.5    Mac Hobby, H.6    Ganapathy, V.7    Leibach, F.H.8
  • 286
    • 0036361009 scopus 로고    scopus 로고
    • A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression
    • DOI 10.1038/sj.tpj.6500099
    • R.L. Roberts, P.R. Joyce, R.T. Mulder, E.J. Begg, and M.A. Kennedy A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression Pharmacogenomics J 2 2002 191 196 (Pubitemid 34982226)
    • (2002) Pharmacogenomics Journal , vol.2 , Issue.3 , pp. 191-196
    • Roberts, R.L.1    Joyce, P.R.2    Mulder, R.T.3    Begg, E.J.4    Kennedy, M.A.5
  • 287
    • 0028117844 scopus 로고
    • Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia
    • S.P. Roose, A.H. Glassman, E. Attia, and S. Woodring Comparative efficacy of selective serotonin reuptake inhibitors and tricyclics in the treatment of melancholia Am J Psychiatry 151 1994 1735 1739 (Pubitemid 24370892)
    • (1994) American Journal of Psychiatry , vol.151 , Issue.12 , pp. 1735-1739
    • Roose, S.P.1    Glassman, A.H.2    Attia, E.3    Woodring, S.4
  • 288
    • 70450203483 scopus 로고    scopus 로고
    • The 5-HT1B receptor: A novel target for the pathophysiology of depression
    • B.M. Ruf, and Z. Bhagwagar The 5-HT1B receptor: a novel target for the pathophysiology of depression Curr Drug Targets 10 2009 1118 1138
    • (2009) Curr Drug Targets , vol.10 , pp. 1118-1138
    • Ruf, B.M.1    Bhagwagar, Z.2
  • 290
    • 0031711343 scopus 로고    scopus 로고
    • A functional polymorphism in the monoamine oxidase A gene promoter
    • DOI 10.1007/s004390050816
    • S.Z. Sabol, S. Hu, and D. Hamer A functional polymorphism in the monoamine oxidase A gene promoter Hum Genet 103 1998 273 279 (Pubitemid 28470076)
    • (1998) Human Genetics , vol.103 , Issue.3 , pp. 273-279
    • Sabol, S.Z.1    Hu, S.2    Hamer, D.3
  • 291
    • 13944257674 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus
    • DOI 10.1523/JNEUROSCI.3741-04.2005
    • M. Sairanen, G. Lucas, P. Ernfors, M. Castren, and E. Castren Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus J Neurosci 25 2005 1089 1094 (Pubitemid 40268949)
    • (2005) Journal of Neuroscience , vol.25 , Issue.5 , pp. 1089-1094
    • Sairanen, M.1    Lucas, G.2    Ernfors, P.3    Castren, M.4    Castren, E.5
  • 292
    • 84878482012 scopus 로고    scopus 로고
    • Effects of antidepressant treatment on mice lacking brain-derived neurotrophic factor expression through promoter IV
    • K. Sakata, J.R. Mastin, S.M. Duke, M.G. Vail, A.E. Overacre, and B.E. Dong et al. Effects of antidepressant treatment on mice lacking brain-derived neurotrophic factor expression through promoter IV Eur J Neurosci 37 11 2013 1863 1874
    • (2013) Eur J Neurosci , vol.37 , Issue.11 , pp. 1863-1874
    • Sakata, K.1    Mastin, J.R.2    Duke, S.M.3    Vail, M.G.4    Overacre, A.E.5    Dong, B.E.6
  • 298
    • 18744412116 scopus 로고    scopus 로고
    • Association between - 1438G/A promoter polymorphism in the 5-HT(2A) receptor gene and fluvoxamine response in Japanese patients with major depressive disorder
    • K. Sato, K. Yoshida, H. Takahashi, K. Ito, M. Kamata, and H. Higuchi et al. Association between - 1438G/A promoter polymorphism in the 5-HT(2A) receptor gene and fluvoxamine response in Japanese patients with major depressive disorder Neuropsychobiology 46 2002 136 140
    • (2002) Neuropsychobiology , vol.46 , pp. 136-140
    • Sato, K.1    Yoshida, K.2    Takahashi, H.3    Ito, K.4    Kamata, M.5    Higuchi, H.6
  • 300
    • 77957734498 scopus 로고    scopus 로고
    • Genetic variants and abnormal processing of pre-miR-182, a circadian clock modulator, in major depression patients with late insomnia
    • E. Saus, V. Soria, G. Escaramis, F. Vivarelli, J.M. Crespo, and B. Kagerbauer et al. Genetic variants and abnormal processing of pre-miR-182, a circadian clock modulator, in major depression patients with late insomnia Hum Mol Genet 19 2010 4017 4025
    • (2010) Hum Mol Genet , vol.19 , pp. 4017-4025
    • Saus, E.1    Soria, V.2    Escaramis, G.3    Vivarelli, F.4    Crespo, J.M.5    Kagerbauer, B.6
  • 301
    • 8744273759 scopus 로고    scopus 로고
    • Effects of dosage and CYP2D6-mutated allele on plasma concentration of paroxetine
    • DOI 10.1007/s00228-004-0792-6
    • K. Sawamura, Y. Suzuki, and T. Someya Effects of dosage and CYP2D6-mutated allele on plasma concentration of paroxetine Eur J Clin Pharmacol 60 2004 553 557 (Pubitemid 39517907)
    • (2004) European Journal of Clinical Pharmacology , vol.60 , Issue.8 , pp. 553-557
    • Sawamura, K.1    Suzuki, Y.2    Someya, T.3
  • 303
    • 0033526176 scopus 로고    scopus 로고
    • P-Glycoprotein, a gatekeeper in the blood-brain barrier
    • DOI 10.1016/S0169-409X(98)00085-4, PII S0169409X98000854
    • A.H. Schinkel P-Glycoprotein, a gatekeeper in the blood-brain barrier Adv Drug Deliv Rev 36 1999 179 194 (Pubitemid 29121971)
    • (1999) Advanced Drug Delivery Reviews , vol.36 , Issue.2-3 , pp. 179-194
    • Schinkel, A.H.1
  • 305
    • 0029892497 scopus 로고    scopus 로고
    • P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
    • A.H. Schinkel, E. Wagenaar, C.A. Mol, and L. van Deemter P-Glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs J Clin Invest 97 1996 2517 2524 (Pubitemid 26187339)
    • (1996) Journal of Clinical Investigation , vol.97 , Issue.11 , pp. 2517-2524
    • Schinkel, A.H.1    Wagenaar, E.2    Mol, C.A.A.M.3    Van Deemter, L.4
  • 308
    • 84859895343 scopus 로고    scopus 로고
    • Behavioural consequences of p-glycoprotein deficiency in mice, with special focus on stress-related mechanisms
    • Y. Schoenfelder, C. Hiemke, and U. Schmitt Behavioural consequences of p-glycoprotein deficiency in mice, with special focus on stress-related mechanisms J Neuroendocrinol 24 2012 809 817
    • (2012) J Neuroendocrinol , vol.24 , pp. 809-817
    • Schoenfelder, Y.1    Hiemke, C.2    Schmitt, U.3
  • 309
    • 84861481592 scopus 로고    scopus 로고
    • European Group for the Study of Resistant Depression (GSRD) - Where have we gone so far: Review of clinical and genetic findings
    • A. Schosser, A. Serretti, D. Souery, J. Mendlewicz, J. Zohar, and S. Montgomery et al. European Group for the Study of Resistant Depression (GSRD) - where have we gone so far: review of clinical and genetic findings Eur Neuropsychopharmacol 22 2012 453 468
    • (2012) Eur Neuropsychopharmacol , vol.22 , pp. 453-468
    • Schosser, A.1    Serretti, A.2    Souery, D.3    Mendlewicz, J.4    Zohar, J.5    Montgomery, S.6
  • 310
    • 0028912433 scopus 로고
    • Vesicular neurotransmitter transporters: From bacteria to humans
    • S. Schuldiner, A. Shirvan, and M. Linial Vesicular neurotransmitter transporters: from bacteria to humans Physiol Rev 75 1995 369 392
    • (1995) Physiol Rev , vol.75 , pp. 369-392
    • Schuldiner, S.1    Shirvan, A.2    Linial, M.3
  • 311
    • 27744566428 scopus 로고    scopus 로고
    • Influence of CYP2C9, 2C19 and 2D6 genetic polymorphisms on the steady-state plasma concentrations of the enantiomers of fluoxetine and norfluoxetine
    • DOI 10.1111/j.1742-7843.2005.pto-194.x
    • M.G. Scordo, E. Spina, M.L. Dahl, G. Gatti, and E. Perucca Influence of CYP2C9, 2C19 and 2D6 genetic polymorphisms on the steady-state plasma concentrations of the enantiomers of fluoxetine and norfluoxetine Basic Clin Pharmacol Toxicol 97 2005 296 301 (Pubitemid 41608122)
    • (2005) Basic and Clinical Pharmacology and Toxicology , vol.97 , Issue.5 , pp. 296-301
    • Scordo, M.G.1    Spina, E.2    Dahl, M.-L.3    Gatti, G.4    Perucca, E.5
  • 312
    • 42349093469 scopus 로고    scopus 로고
    • Novel monoamine oxidase A knock out mice with human-like spontaneous mutation
    • DOI 10.1097/WNR.0b013e3282fd6e88, PII 0000175620080507000007
    • A.L. Scott, M. Bortolato, K. Chen, and J.C. Shih Novel monoamine oxidase A knock out mice with human-like spontaneous mutation Neuroreport 19 2008 739 743 (Pubitemid 351555982)
    • (2008) NeuroReport , vol.19 , Issue.7 , pp. 739-743
    • Scott, A.L.1    Bortolato, M.2    Chen, K.3    Shih, J.C.4
  • 313
    • 0032781402 scopus 로고    scopus 로고
    • Tryptophan hydroxylase gene and response to lithium prophylaxis in mood disorders
    • DOI 10.1016/S0022-3956(99)00013-8, PII S0022395699000138
    • A. Serretti, R. Lilli, C. Lorenzi, M. Gasperini, and E. Smeraldi Tryptophan hydroxylase gene and response to lithium prophylaxis in mood disorders J Psychiatr Res 33 1999 371 377 (Pubitemid 29392685)
    • (1999) Journal of Psychiatric Research , vol.33 , Issue.5 , pp. 371-377
    • Serretti, A.1    Lilli, R.2    Lorenzi, C.3    Gasperini, M.4    Smeraldi, E.5
  • 314
    • 0034795789 scopus 로고    scopus 로고
    • Tryptophan hydroxylase gene associated with paroxetine antidepressant activity
    • DOI 10.1016/S0924-977X(01)00113-4, PII S0924977X01001134
    • A. Serretti, R. Zanardi, C. Cusin, D. Rossini, C. Lorenzi, and E. Smeraldi Tryptophan hydroxylase gene associated with paroxetine antidepressant activity Eur Neuropsychopharmacol 11 2001 375 380 (Pubitemid 32946888)
    • (2001) European Neuropsychopharmacology , vol.11 , Issue.5 , pp. 375-380
    • Serretti, A.1    Zanardi, R.2    Cusin, C.3    Rossini, D.4    Lorenzi, C.5    Smeraldi, E.6
  • 315
    • 0034885170 scopus 로고    scopus 로고
    • Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity
    • DOI 10.1038/sj.mp.4000876
    • A. Serretti, R. Zanardi, D. Rossini, C. Cusin, R. Lilli, and E. Smeraldi Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity Mol Psychiatry 6 2001 586 592 (Pubitemid 32772568)
    • (2001) Molecular Psychiatry , vol.6 , Issue.5 , pp. 586-592
    • Serretti, A.1    Zanardi, R.2    Rossini, D.3    Cusin, C.4    Lilli, R.5    Smeraldi, E.6
  • 316
    • 10644271666 scopus 로고    scopus 로고
    • The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: Preliminary findings
    • DOI 10.1017/S1461145704004687
    • A. Serretti, P. Artioli, C. Lorenzi, A. Pirovano, V. Tubazio, and R. Zanardi The C(- 1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings Int J Neuropsychopharmacol 7 2004 453 460 (Pubitemid 39648075)
    • (2004) International Journal of Neuropsychopharmacology , vol.7 , Issue.4 , pp. 453-460
    • Serretti, A.1    Artioli, P.2    Lorenzi, C.3    Pirovano, A.4    Tubazio, V.5    Zanardi, R.6
  • 318
    • 4644332454 scopus 로고    scopus 로고
    • Pharmacogenetics of selective serotonin reuptake inhibitor response: A 6-month follow-up
    • DOI 10.1097/00008571-200409000-00005
    • A. Serretti, R. Zanardi, L. Franchini, P. Artioli, D. Dotoli, and A. Pirovano et al. Pharmacogenetics of selective serotonin reuptake inhibitor response: a 6-month follow-up Pharmacogenetics 14 2004 607 613 (Pubitemid 39281815)
    • (2004) Pharmacogenetics , vol.14 , Issue.9 , pp. 607-613
    • Serretti, A.1    Zanardi, R.2    Franchini, L.3    Artioli, P.4    Dotoli, D.5    Pirovano, A.6    Smeraldi, E.7
  • 319
    • 33847257284 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients
    • DOI 10.1038/sj.mp.4001926, PII 4001926
    • A. Serretti, M. Kato, D. De Ronchi, and T. Kinoshita Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients Mol Psychiatry 12 2007 247 257 (Pubitemid 46328503)
    • (2007) Molecular Psychiatry , vol.12 , Issue.3 , pp. 247-257
    • Serretti, A.1    Kato, M.2    De Ronchi, D.3    Kinoshita, T.4
  • 320
    • 40949152450 scopus 로고    scopus 로고
    • Pharmacogenetic studies in depression: A proposal for methodologic guidelines
    • DOI 10.1038/sj.tpj.6500477, PII 6500477
    • A. Serretti, M. Kato, and J.L. Kennedy Pharmacogenetic studies in depression: a proposal for methodologic guidelines Pharmacogenomics J 8 2008 90 100 (Pubitemid 351411545)
    • (2008) Pharmacogenomics Journal , vol.8 , Issue.2 , pp. 90-100
    • Serretti, A.1    Kato, M.2    Kennedy, J.L.3
  • 321
    • 69549135357 scopus 로고    scopus 로고
    • Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes are not associated with response and remission in a sample of depressive patients
    • A. Serretti, R. Calati, I. Massat, S. Linotte, S. Kasper, and Y. Lecrubier et al. Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes are not associated with response and remission in a sample of depressive patients Int Clin Psychopharmacol 24 2009 250 256
    • (2009) Int Clin Psychopharmacol , vol.24 , pp. 250-256
    • Serretti, A.1    Calati, R.2    Massat, I.3    Linotte, S.4    Kasper, S.5    Lecrubier, Y.6
  • 322
    • 80051690979 scopus 로고    scopus 로고
    • Influence of TPH2 variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia
    • A. Serretti, A. Chiesa, S. Porcelli, C. Han, A.A. Patkar, and S.J. Lee et al. Influence of TPH2 variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia Psychiatry Res 189 2011 26 32
    • (2011) Psychiatry Res , vol.189 , pp. 26-32
    • Serretti, A.1    Chiesa, A.2    Porcelli, S.3    Han, C.4    Patkar, A.A.5    Lee, S.J.6
  • 323
    • 84855389473 scopus 로고    scopus 로고
    • Failure to replicate influence of GRIK4 and GNB3 polymorphisms on treatment outcome in major depression
    • A. Serretti, A. Chiesa, C. Crisafulli, I. Massat, S. Linotte, and R. Calati et al. Failure to replicate influence of GRIK4 and GNB3 polymorphisms on treatment outcome in major depression Neuropsychobiology 65 2012 70 75
    • (2012) Neuropsychobiology , vol.65 , pp. 70-75
    • Serretti, A.1    Chiesa, A.2    Crisafulli, C.3    Massat, I.4    Linotte, S.5    Calati, R.6
  • 327
    • 79151475816 scopus 로고    scopus 로고
    • Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies
    • S.I. Shyn, J. Shi, J.B. Kraft, J.B. Potash, J.A. Knowles, and M.M. Weissman et al. Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies Mol Psychiatry 16 2011 202 215
    • (2011) Mol Psychiatry , vol.16 , pp. 202-215
    • Shyn, S.I.1    Shi, J.2    Kraft, J.B.3    Potash, J.B.4    Knowles, J.A.5    Weissman, M.M.6
  • 328
    • 77955090863 scopus 로고    scopus 로고
    • Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice
    • W.B. Siesser, X. Zhang, J.P. Jacobsen, T.D. Sotnikova, R.R. Gainetdinov, and M.G. Caron Tryptophan hydroxylase 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice Neurosci Lett 481 2010 6 11
    • (2010) Neurosci Lett , vol.481 , pp. 6-11
    • Siesser, W.B.1    Zhang, X.2    Jacobsen, J.P.3    Sotnikova, T.D.4    Gainetdinov, R.R.5    Caron, M.G.6
  • 330
    • 84870837641 scopus 로고    scopus 로고
    • ABCB1 polymorphism predicts escitalopram dose needed for remission in major depression
    • A.B. Singh, C.A. Bousman, C.H. Ng, K. Byron, and M. Berk ABCB1 polymorphism predicts escitalopram dose needed for remission in major depression Transl Psychiatry 2 2012 e198
    • (2012) Transl Psychiatry , vol.2 , pp. 198
    • Singh, A.B.1    Bousman, C.A.2    Ng, C.H.3    Byron, K.4    Berk, M.5
  • 331
  • 332
    • 0031736757 scopus 로고    scopus 로고
    • Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
    • E. Smeraldi, R. Zanardi, F. Benedetti, D. Di Bella, J. Perez, and M. Catalano Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine Mol Psychiatry 3 1998 508 511 (Pubitemid 28515526)
    • (1998) Molecular Psychiatry , vol.3 , Issue.6 , pp. 508-511
    • Smeraldi, E.1    Zanardi, R.2    Benedetti, F.3    Di Bella, D.4    Perez, J.5    Catalano, M.6
  • 334
    • 84855971940 scopus 로고    scopus 로고
    • Prenatal fluoxetine exposure induces life-long serotonin 5-HT(3) receptor-dependent cortical abnormalities and anxiety-like behaviour
    • L.A. Smit-Rigter, C.W. Noorlander, L. von Oerthel, P. Chameau, M.P. Smidt, and J.A. van Hooft Prenatal fluoxetine exposure induces life-long serotonin 5-HT(3) receptor-dependent cortical abnormalities and anxiety-like behaviour Neuropharmacology 62 2012 865 870
    • (2012) Neuropharmacology , vol.62 , pp. 865-870
    • Smit-Rigter, L.A.1    Noorlander, C.W.2    Von Oerthel, L.3    Chameau, P.4    Smidt, M.P.5    Van Hooft, J.A.6
  • 335
    • 0031028101 scopus 로고    scopus 로고
    • Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: A prospective study
    • DOI 10.1007/s002280050220
    • E. Spina, C. Gitto, A. Avenoso, G.M. Campo, A.P. Caputi, and E. Perucca Relationship between plasma desipramine levels, CYP2D6 phenotype and clinical response to desipramine: a prospective study Eur J Clin Pharmacol 51 1997 395 398 (Pubitemid 27055908)
    • (1997) European Journal of Clinical Pharmacology , vol.51 , Issue.5 , pp. 395-398
    • Spina, E.1    Gitto, C.2    Avenoso, A.3    Campo, G.M.4    Caputi, A.P.5    Perucca, E.6
  • 336
    • 33645340038 scopus 로고    scopus 로고
    • Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia
    • A. Spudich, E. Kilic, H.Y. Xing, U. Kilic, K.M. Rentsch, and H. Wunderli-Allenspach et al. Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia Nat Neurosci 9 2006 487 488
    • (2006) Nat Neurosci , vol.9 , pp. 487-488
    • Spudich, A.1    Kilic, E.2    Xing, H.Y.3    Kilic, U.4    Rentsch, K.M.5    Wunderli-Allenspach, H.6
  • 337
    • 0035989059 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 genotype does not predict SSRI (fluoxetine or paroxetine) induced hyponatraemia
    • DOI 10.1002/hup.394
    • C.A. Stedman, E.J. Begg, M.A. Kennedy, R. Roberts, and T.J. Wilkinson Cytochrome P450 2D6 genotype does not predict SSRI (fluoxetine or paroxetine) induced hyponatraemia Hum Psychopharmacol 17 2002 187 190 (Pubitemid 34678880)
    • (2002) Human Psychopharmacology , vol.17 , Issue.4 , pp. 187-190
    • Stedman, C.A.M.1    Begg, E.J.2    Kennedy, M.A.3    Roberts, R.4    Wilkinson, T.J.5
  • 338
    • 4344613464 scopus 로고    scopus 로고
    • Allele-specific change of concentration and functional gene dose for the prediction of steady-state serum concentrations of amitriptyline and nortriptyline in CYP2C19 and CYP2D6 extensive and intermediate metabolizers
    • DOI 10.1373/clinchem.2003.030825
    • W. Steimer, K. Zopf, S. von Amelunxen, H. Pfeiffer, J. Bachofer, and J. Popp et al. Allele-specific change of concentration and functional gene dose for the prediction of steady-state serum concentrations of amitriptyline and nortriptyline in CYP2C19 and CYP2D6 extensive and intermediate metabolizers Clin Chem 50 2004 1623 1633 (Pubitemid 39121231)
    • (2004) Clinical Chemistry , vol.50 , Issue.9 , pp. 1623-1633
    • Steimer, W.1    Zopf, K.2    Von Amelunxen, S.3    Pfeiffer, H.4    Bachofer, J.5    Popp, J.6    Messner, B.7    Kissling, W.8    Leucht, S.9
  • 339
    • 12944281041 scopus 로고    scopus 로고
    • Amitriptyline or not, that is the question: Pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy
    • DOI 10.1373/clinchem.2004.041327
    • W. Steimer, K. Zopf, S. von Amelunxen, H. Pfeiffer, J. Bachofer, and J. Popp et al. Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy Clin Chem 51 2005 376 385 (Pubitemid 40175808)
    • (2005) Clinical Chemistry , vol.51 , Issue.2 , pp. 376-385
    • Steimer, W.1    Zopf, K.2    Von Amelunxen, S.3    Pfeiffer, H.4    Bachofer, J.5    Popp, J.6    Messner, B.7    Kissling, W.8    Leucht, S.9
  • 340
    • 80052839502 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor is associated with alcohol dependence-related depression and antidepressant response
    • N. Su, L. Zhang, F. Fei, H. Hu, K. Wang, and H. Hui et al. The brain-derived neurotrophic factor is associated with alcohol dependence-related depression and antidepressant response Brain Res 1415 2011 119 126
    • (2011) Brain Res , vol.1415 , pp. 119-126
    • Su, N.1    Zhang, L.2    Fei, F.3    Hu, H.4    Wang, K.5    Hui, H.6
  • 341
    • 33749252329 scopus 로고    scopus 로고
    • The effect of 5-hydroxytryptamine 3A and 3B receptor genes on nausea induced by paroxetine
    • DOI 10.1038/sj.tpj.6500382, PII 6500382
    • T. Sugai, Y. Suzuki, K. Sawamura, N. Fukui, Y. Inoue, and T. Someya The effect of 5-hydroxytryptamine 3A and 3B receptor genes on nausea induced by paroxetine Pharmacogenomics J 6 2006 351 356 (Pubitemid 44480155)
    • (2006) Pharmacogenomics Journal , vol.6 , Issue.5 , pp. 351-356
    • Sugai, T.1    Suzuki, Y.2    Sawamura, K.3    Fukui, N.4    Inoue, Y.5    Someya, T.6
  • 342
    • 4344637548 scopus 로고    scopus 로고
    • The effects of a 5-hydroxytryptamine 1A receptor gene polymorphism on the clinical response to fluvoxamine in depressed patients
    • DOI 10.1038/sj.tpj.6500256
    • Y. Suzuki, K. Sawamura, and T. Someya The effects of a 5-hydroxytryptamine 1A receptor gene polymorphism on the clinical response to fluvoxamine in depressed patients Pharmacogenomics J 4 2004 283 286 (Pubitemid 39136772)
    • (2004) Pharmacogenomics Journal , vol.4 , Issue.4 , pp. 283-286
    • Suzuki, Y.1    Sawamura, K.2    Someya, T.3
  • 346
    • 61449118888 scopus 로고    scopus 로고
    • Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport
    • S. Syvanen, O. Lindhe, M. Palner, B.R. Kornum, O. Rahman, and B. Langstrom et al. Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport Drug Metab Dispos 37 2009 635 643
    • (2009) Drug Metab Dispos , vol.37 , pp. 635-643
    • Syvanen, S.1    Lindhe, O.2    Palner, M.3    Kornum, B.R.4    Rahman, O.5    Langstrom, B.6
  • 347
    • 13544263559 scopus 로고    scopus 로고
    • 108/158Met polymorphism affects short-term treatment response to mirtazapine, but not to paroxetine in major depression
    • DOI 10.1038/sj.tpj.6500289
    • A. Szegedi, D. Rujescu, A. Tadic, M.J. Muller, R. Kohnen, and H.H. Stassen et al. The catechol-O-methyltransferase Val108/158Met polymorphism affects short-term treatment response to mirtazapine, but not to paroxetine in major depression Pharmacogenomics J 5 2005 49 53 (Pubitemid 40220617)
    • (2005) Pharmacogenomics Journal , vol.5 , Issue.1 , pp. 49-53
    • Szegedi, A.1    Rujescu, D.2    Tadic, A.3    Muller, M.J.4    Kohnen, R.5    Stassen, H.H.6    Dahmen, N.7
  • 350
    • 77956170298 scopus 로고    scopus 로고
    • Antidepressant response and the serotonin transporter gene-linked polymorphic region
    • M.J. Taylor, S. Sen, and Z. Bhagwagar Antidepressant response and the serotonin transporter gene-linked polymorphic region Biol Psychiatry 68 2010 536 543
    • (2010) Biol Psychiatry , vol.68 , pp. 536-543
    • Taylor, M.J.1    Sen, S.2    Bhagwagar, Z.3
  • 352
    • 38049004434 scopus 로고    scopus 로고
    • The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains
    • K. Tenner, F. Qadri, B. Bert, J.P. Voigt, and M. Bader The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioural differences between mouse strains Neurosci Lett 431 2008 21 25
    • (2008) Neurosci Lett , vol.431 , pp. 21-25
    • Tenner, K.1    Qadri, F.2    Bert, B.3    Voigt, J.P.4    Bader, M.5
  • 354
    • 0024576304 scopus 로고
    • Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: Evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein
    • F. Thiebaut, T. Tsuruo, H. Hamada, M.M. Gottesman, I. Pastan, and M.C. Willingham Immunohistochemical localization in normal-tissues of different epitopes in the multidrug transport protein P170 - evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein J Histochem Cytochem 37 1989 159 164 (Pubitemid 19039163)
    • (1989) Journal of Histochemistry and Cytochemistry , vol.37 , Issue.2 , pp. 159-164
    • Thiebaut, F.1    Tsuruo, T.2    Hamada, H.3    Gottesman, M.M.4    Pastan, I.5    Willingham, M.C.6
  • 355
    • 0028866230 scopus 로고
    • Neurotrophins and neuronal plasticity
    • H. Thoenen Neurotrophins and neuronal plasticity Science 270 1995 593 598
    • (1995) Science , vol.270 , pp. 593-598
    • Thoenen, H.1
  • 356
    • 0028935117 scopus 로고
    • Noradrenaline is essential for mouse fetal development
    • S.A. Thomas, A.M. Matsumoto, and R.D. Palmiter Noradrenaline is essential for mouse fetal development Nature 374 1995 643 646
    • (1995) Nature , vol.374 , pp. 643-646
    • Thomas, S.A.1    Matsumoto, A.M.2    Palmiter, R.D.3
  • 357
    • 37349048084 scopus 로고    scopus 로고
    • Association of a dopamine beta-hydroxylase gene variant with depression in elderly women possibly reflecting noradrenergic dysfunction
    • DOI 10.1016/j.jad.2007.06.010, PII S0165032707002352
    • M. Togsverd, T.M. Werge, L.B. Tanko, Y.Z. Bagger, T. Hansen, and G. Qin et al. Association of a dopamine beta-hydroxylase gene variant with depression in elderly women possibly reflecting noradrenergic dysfunction J Affect Disord 106 2008 169 172 (Pubitemid 350309676)
    • (2008) Journal of Affective Disorders , vol.106 , Issue.1-2 , pp. 169-172
    • Togsverd, M.1    Werge, T.M.2    Tanko, L.B.3    Bagger, Y.Z.4    Hansen, T.5    Qin, G.6    Christiansen, C.7    Rasmussen, H.B.8
  • 360
    • 4644264502 scopus 로고    scopus 로고
    • Association study of serotonin 1B receptor (A-161T) genetic polymorphism and suicidal behaviors and response to fluoxetine in major depressive disorder
    • DOI 10.1159/000079977
    • S.J. Tsai, C.J. Hong, Y.W. Yu, T.J. Chen, Y.C. Wang, and W.K. Lin Association study of serotonin 1B receptor (A-161T) genetic polymorphism and suicidal behaviors and response to fluoxetine in major depressive disorder Neuropsychobiology 50 2004 235 238 (Pubitemid 39279417)
    • (2004) Neuropsychobiology , vol.50 , Issue.3 , pp. 235-238
    • Tsai, S.-J.1    Hong, C.-J.2    Yu, Y.W.-Y.3    Chen, T.-J.4    Wang, Y.-C.5    Lin, W.-K.6
  • 361
    • 58149097604 scopus 로고    scopus 로고
    • Sexually dimorphic effect of catechol-O-methyltransferase val158met polymorphism on clinical response to fluoxetine in major depressive patients
    • S.J. Tsai, Y.T. Gau, C.J. Hong, Y.J. Liou, Y.W. Yu, and T.J. Chen Sexually dimorphic effect of catechol-O-methyltransferase val158met polymorphism on clinical response to fluoxetine in major depressive patients J Affect Disord 113 2009 183 187
    • (2009) J Affect Disord , vol.113 , pp. 183-187
    • Tsai, S.J.1    Gau, Y.T.2    Hong, C.J.3    Liou, Y.J.4    Yu, Y.W.5    Chen, T.J.6
  • 362
    • 77950350248 scopus 로고    scopus 로고
    • Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response
    • M.H. Tsai, K.M. Lin, M.C. Hsiao, W.W. Shen, M.L. Lu, and H.S. Tang et al. Genetic polymorphisms of cytochrome P450 enzymes influence metabolism of the antidepressant escitalopram and treatment response Pharmacogenomics 11 2010 537 546
    • (2010) Pharmacogenomics , vol.11 , pp. 537-546
    • Tsai, M.H.1    Lin, K.M.2    Hsiao, M.C.3    Shen, W.W.4    Lu, M.L.5    Tang, H.S.6
  • 363
    • 33749487425 scopus 로고    scopus 로고
    • MicroRNA regulates the expression of human cytochrome P450 1B1
    • DOI 10.1158/0008-5472.CAN-06-1403
    • Y. Tsuchiya, M. Nakajima, S. Takagi, T. Taniya, and T. Yokoi MicroRNA regulates the expression of human cytochrome P450 1B1 Cancer Res 66 2006 9090 9098 (Pubitemid 44521128)
    • (2006) Cancer Research , vol.66 , Issue.18 , pp. 9090-9098
    • Tsuchiya, Y.1    Nakajima, M.2    Takagi, S.3    Taniya, T.4    Yokoi, T.5
  • 364
    • 67649220685 scopus 로고    scopus 로고
    • Association analysis of group II metabotropic glutamate receptor genes (GRM2 and GRM3) with mood disorders and fluvoxamine response in a Japanese population
    • T. Tsunoka, T. Kishi, M. Ikeda, T. Kitajima, Y. Yamanouchi, and Y. Kinoshita et al. Association analysis of group II metabotropic glutamate receptor genes (GRM2 and GRM3) with mood disorders and fluvoxamine response in a Japanese population Prog Neuropsychopharmacol Biol Psychiatry 33 2009 875 879
    • (2009) Prog Neuropsychopharmacol Biol Psychiatry , vol.33 , pp. 875-879
    • Tsunoka, T.1    Kishi, T.2    Ikeda, M.3    Kitajima, T.4    Yamanouchi, Y.5    Kinoshita, Y.6
  • 365
    • 84858662491 scopus 로고    scopus 로고
    • Optogenetic investigation of neural circuits underlying brain disease in animal models
    • K.M. Tye, and K. Deisseroth Optogenetic investigation of neural circuits underlying brain disease in animal models Nat Rev Neurosci 13 2012 251 266
    • (2012) Nat Rev Neurosci , vol.13 , pp. 251-266
    • Tye, K.M.1    Deisseroth, K.2
  • 366
    • 68049137696 scopus 로고    scopus 로고
    • MAOA gene polymorphisms and response to mirtazapine in major depression
    • D.S. Tzeng, C.C. Chien, F.W. Lung, and C.Y. Yang MAOA gene polymorphisms and response to mirtazapine in major depression Hum Psychopharmacol 24 2009 293 300
    • (2009) Hum Psychopharmacol , vol.24 , pp. 293-300
    • Tzeng, D.S.1    Chien, C.C.2    Lung, F.W.3    Yang, C.Y.4
  • 367
    • 44449124504 scopus 로고    scopus 로고
    • Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment
    • DOI 10.1097/FPC.0b013e3282fb02cb, PII 0121301120080600000006
    • M.V. Tzvetkov, J. Brockmoller, I. Roots, and J. Kirchheiner Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment Pharmacogenet Genomics 18 2008 495 506 (Pubitemid 351769917)
    • (2008) Pharmacogenetics and Genomics , vol.18 , Issue.6 , pp. 495-506
    • Tzvetkov, M.V.1    Brockmoller, J.2    Roots, I.3    Kirchheiner, J.4
  • 369
    • 56449101949 scopus 로고    scopus 로고
    • The implications of gene-environment interactions in depression: Will cause inform cure?
    • R. Uher The implications of gene-environment interactions in depression: will cause inform cure? Mol Psychiatry 13 2008 1070 1078
    • (2008) Mol Psychiatry , vol.13 , pp. 1070-1078
    • Uher, R.1
  • 371
    • 0037400655 scopus 로고    scopus 로고
    • Abcblab P-glycoprotein is involved in the uptake of citalopram and trimipramine into the brain of mice
    • DOI 10.1016/S0022-3956(03)00022-0
    • M. Uhr, and M.T. Grauer abcblab P-glycoprotein is involved in the uptake of citalopram and trimipramine into the brain of mice J Psychiatr Res 37 2003 179 185 (Pubitemid 36313270)
    • (2003) Journal of Psychiatric Research , vol.37 , Issue.3 , pp. 179-185
    • Uhr, M.1    Grauer, M.T.2
  • 372
    • 0033952456 scopus 로고    scopus 로고
    • Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to Mdr1a P-glycoprotein gene disruption
    • DOI 10.1016/S0893-133X(99)00095-0, PII S0893133X99000950
    • M. Uhr, T. Steckler, A. Yassouridis, and F. Holsboer Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to Mdr1a P-glycoprotein gene disruption Neuropsychopharmacology 22 2000 380 387 (Pubitemid 30105766)
    • (2000) Neuropsychopharmacology , vol.22 , Issue.4 , pp. 380-387
    • Uhr, M.1    Steckler, T.2    Yassouridis, A.3    Holsboer, F.4
  • 373
    • 0141783736 scopus 로고    scopus 로고
    • Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-Glycoprotein gene disruption
    • DOI 10.1016/S0006-3223(03)00074-X
    • M. Uhr, M.T. Grauer, and F. Holsboer Differential enhancement of antidepressant penetration into the brain in mice with abcb1ab (mdr1ab) P-glycoprotein gene disruption Biol Psychiatry 54 2003 840 846 (Pubitemid 37205136)
    • (2003) Biological Psychiatry , vol.54 , Issue.8 , pp. 840-846
    • Uhr, M.1    Grauer, M.T.2    Holsboer, F.3
  • 374
    • 33750736012 scopus 로고    scopus 로고
    • Blood-brain barrier penetration and pharmacokinetics of amitriptyline and its metabolites in p-glycoprotein (abcb1ab) knock-out mice and controls
    • DOI 10.1016/j.jpsychires.2005.10.005, PII S0022395605001329
    • M. Uhr, M.T. Grauer, A. Yassouridis, and M. Ebinger Blood-brain barrier penetration and pharmacokinetics of amitriptyline and its metabolites in p-glycoprotein (abcb1ab) knock-out mice and controls J Psychiatr Res 41 2007 179 188 (Pubitemid 44708204)
    • (2007) Journal of Psychiatric Research , vol.41 , Issue.1-2 , pp. 179-188
    • Uhr, M.1    Grauer, M.T.2    Yassouridis, A.3    Ebinger, M.4
  • 375
    • 38149003759 scopus 로고    scopus 로고
    • Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression
    • M. Uhr, A. Tontsch, C. Namendorf, S. Ripke, S. Lucae, and M. Ising et al. Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression Neuron 57 2008 203 209
    • (2008) Neuron , vol.57 , pp. 203-209
    • Uhr, M.1    Tontsch, A.2    Namendorf, C.3    Ripke, S.4    Lucae, S.5    Ising, M.6
  • 376
    • 33644811359 scopus 로고    scopus 로고
    • Response to Zhang et al (2005): Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression
    • (Neuron. 2005; 48:704; author reply 5-6)
    • A. Van Den Bogaert, S. De Zutter, L. Heyrman, J. Mendlewicz, R. Adolfsson, and C. Van Broeckhoven et al. Response to Zhang et al (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression Neuron 45 2005 11 16 (Neuron. 2005; 48:704; author reply 5-6)
    • (2005) Neuron , vol.45 , pp. 11-16
    • Van Den Bogaert, A.1    De Zutter, S.2    Heyrman, L.3    Mendlewicz, J.4    Adolfsson, R.5    Van Broeckhoven, C.6
  • 378
    • 80053098815 scopus 로고    scopus 로고
    • Therapeutic options in treatment-resistant depression
    • E. Vieta, and F. Colom Therapeutic options in treatment-resistant depression Ann Med 43 2011 512 530
    • (2011) Ann Med , vol.43 , pp. 512-530
    • Vieta, E.1    Colom, F.2
  • 380
    • 0037414862 scopus 로고    scopus 로고
    • Synthesis of serotonin by a second tryptophan hydroxylase isoform
    • DOI 10.1126/science.1078197
    • D.J. Walther, J.U. Peter, S. Bashammakh, H. Hortnagl, M. Voits, and H. Fink et al. Synthesis of serotonin by a second tryptophan hydroxylase isoform Science 299 2003 76 (Pubitemid 36042402)
    • (2003) Science , vol.299 , Issue.5603 , pp. 76
    • Walther, D.J.1    Peter, J.-U.2    Bashammakh, S.3    Hortnagl, H.4    Voits, M.5    Fink, H.6    Bader, M.7
  • 382
    • 79952488880 scopus 로고    scopus 로고
    • TPH1 is associated with major depressive disorder but not with SSRI/SNRI response in Taiwanese patients
    • H.C. Wang, T.L. Yeh, H.H. Chang, P.W. Gean, M.H. Chi, and Y.K. Yang et al. TPH1 is associated with major depressive disorder but not with SSRI/SNRI response in Taiwanese patients Psychopharmacology (Berl) 213 2011 773 779
    • (2011) Psychopharmacology (Berl) , vol.213 , pp. 773-779
    • Wang, H.C.1    Yeh, T.L.2    Chang, H.H.3    Gean, P.W.4    Chi, M.H.5    Yang, Y.K.6
  • 383
    • 37349044684 scopus 로고    scopus 로고
    • The STAR*D project results: A comprehensive review of findings
    • DOI 10.1007/s11920-007-0061-3
    • D. Warden, A.J. Rush, M.H. Trivedi, M. Fava, and S.R. Wisniewski The STAR*D project results: a comprehensive review of findings Curr Psychiatry Rep 9 2007 449 459 (Pubitemid 350284935)
    • (2007) Current Psychiatry Reports , vol.9 , Issue.6 , pp. 449-459
    • Warden, D.1    Rush, A.J.2    Trivedi, M.H.3    Fava, M.4    Wisniewski, S.R.5
  • 386
    • 77957983253 scopus 로고    scopus 로고
    • Potential role of the 5-HT6 receptor in depression and anxiety: An overview of preclinical data
    • A. Wesolowska Potential role of the 5-HT6 receptor in depression and anxiety: an overview of preclinical data Pharmacol Rep 62 2010 564 577
    • (2010) Pharmacol Rep , vol.62 , pp. 564-577
    • Wesolowska, A.1
  • 389
    • 79959573043 scopus 로고    scopus 로고
    • Vesicular monoamine transporters: Structure-function, pharmacology, and medicinal chemistry
    • K. Wimalasena Vesicular monoamine transporters: structure-function, pharmacology, and medicinal chemistry Med Res Rev 31 2011 483 519
    • (2011) Med Res Rev , vol.31 , pp. 483-519
    • Wimalasena, K.1
  • 390
    • 0036501648 scopus 로고    scopus 로고
    • A polymorphism in the dopamine β-hydroxylase gene is associated with "paranoid ideation" in patients with major depression
    • DOI 10.1016/S0006-3223(01)01367-1, PII S0006322301013671
    • J.G. Wood, P.R. Joyce, A.L. Miller, R.T. Mulder, and M.A. Kennedy A polymorphism in the dopamine beta-hydroxylase gene is associated with "paranoid ideation" in patients with major depression Biol Psychiatry 51 2002 365 369 (Pubitemid 34251173)
    • (2002) Biological Psychiatry , vol.51 , Issue.5 , pp. 365-369
    • Wood, J.G.1    Joyce, P.R.2    Miller, A.L.3    Mulder, R.T.4    Kennedy, M.A.5
  • 391
    • 0034764508 scopus 로고    scopus 로고
    • Association study of the 5-HT(6) receptor polymorphism (C267T) and symptomatology and antidepressant response in major depressive disorders
    • W.H. Wu, S.J. Huo, C.Y. Cheng, C.J. Hong, and S.J. Tsai Association study of the 5-HT(6) receptor polymorphism (C267T) and symptomatology and antidepressant response in major depressive disorders Neuropsychobiology 44 2001 172 175
    • (2001) Neuropsychobiology , vol.44 , pp. 172-175
    • Wu, W.H.1    Huo, S.J.2    Cheng, C.Y.3    Hong, C.J.4    Tsai, S.J.5
  • 392
    • 78149357726 scopus 로고    scopus 로고
    • A polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveform
    • Y. Xu, H. Liu, F. Li, N. Sun, Y. Ren, and Z. Liu et al. A polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveform J Affect Disord 127 2010 332 336
    • (2010) J Affect Disord , vol.127 , pp. 332-336
    • Xu, Y.1    Liu, H.2    Li, F.3    Sun, N.4    Ren, Y.5    Liu, Z.6
  • 393
    • 80051664842 scopus 로고    scopus 로고
    • Influence and interaction of genetic polymorphisms in catecholamine neurotransmitter systems and early life stress on antidepressant drug response
    • Z. Xu, Z. Zhang, Y. Shi, M. Pu, Y. Yuan, and X. Zhang et al. Influence and interaction of genetic polymorphisms in catecholamine neurotransmitter systems and early life stress on antidepressant drug response J Affect Disord 133 2011 165 173
    • (2011) J Affect Disord , vol.133 , pp. 165-173
    • Xu, Z.1    Zhang, Z.2    Shi, Y.3    Pu, M.4    Yuan, Y.5    Zhang, X.6
  • 394
    • 84863242826 scopus 로고    scopus 로고
    • Influence and interaction of genetic polymorphisms in the serotonin system and life stress on antidepressant drug response
    • Z. Xu, Z. Zhang, Y. Shi, M. Pu, Y. Yuan, and X. Zhang et al. Influence and interaction of genetic polymorphisms in the serotonin system and life stress on antidepressant drug response J Psychopharmacol 26 2012 349 359
    • (2012) J Psychopharmacol , vol.26 , pp. 349-359
    • Xu, Z.1    Zhang, Z.2    Shi, Y.3    Pu, M.4    Yuan, Y.5    Zhang, X.6
  • 397
    • 0034088327 scopus 로고    scopus 로고
    • Relationship of paroxetine disposition to metroprolol metabolic ratio and CYP2D6*10 genotype of Korean subjects
    • Y.R. Yoon, I.J. Cha, J.H. Shon, K.A. Kim, Y.N. Cha, and I.J. Jang et al. Relationship of paroxetine disposition to metroprolol metabolic ratio and CYP2D6*10 genotype of Korean subjects Clin Pharmacol Ther 67 2000 567 576
    • (2000) Clin Pharmacol Ther , vol.67 , pp. 567-576
    • Yoon, Y.R.1    Cha, I.J.2    Shon, J.H.3    Kim, K.A.4    Cha, Y.N.5    Jang, I.J.6
  • 400
    • 34249317809 scopus 로고    scopus 로고
    • The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine
    • DOI 10.1177/0269881106072192
    • K. Yoshida, H. Higuchi, M. Kamata, H. Takahashi, K. Inoue, and T. Suzuki et al. The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine J Psychopharmacol 21 2007 650 656 (Pubitemid 47472727)
    • (2007) Journal of Psychopharmacology , vol.21 , Issue.6 , pp. 650-656
    • Yoshida, K.1    Higuchi, H.2    Kamata, M.3    Takahashi, H.4    Inoue, K.5    Suzuki, T.6    Itoh, K.7    Ozaki, N.8
  • 401
    • 40549116656 scopus 로고    scopus 로고
    • Influence of the tyrosine hydroxylase val81met polymorphism and catechol-O-methyltransferase val158met polymorphism on the antidepressant effect of milnacipran
    • DOI 10.1002/hup.907
    • K. Yoshida, H. Higuchi, H. Takahashi, M. Kamata, K. Sato, and K. Inoue et al. Influence of the tyrosine hydroxylase val81met polymorphism and catechol-O-methyltransferase val158met polymorphism on the antidepressant effect of milnacipran Hum Psychopharmacol 23 2008 121 128 (Pubitemid 351359584)
    • (2008) Human Psychopharmacology , vol.23 , Issue.2 , pp. 121-128
    • Yoshida, K.1    Higuchi, H.2    Takahashi, H.3    Kamata, M.4    Sato, K.5    Inoue, K.6    Suzuki, T.7    Itoh, K.8    Ozaki, N.9
  • 402
    • 79956009846 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor (BDNF) polymorphism Val66Met is associated with neither serum BDNF level nor response to selective serotonin reuptake inhibitors in depressed Japanese patients
    • R. Yoshimura, T. Kishi, A. Suzuki, W. Umene-Nakano, A. Ikenouchi-Sugita, and H. Hori et al. The brain-derived neurotrophic factor (BDNF) polymorphism Val66Met is associated with neither serum BDNF level nor response to selective serotonin reuptake inhibitors in depressed Japanese patients Prog Neuropsychopharmacol Biol Psychiatry 35 2011 1022 1025
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , pp. 1022-1025
    • Yoshimura, R.1    Kishi, T.2    Suzuki, A.3    Umene-Nakano, W.4    Ikenouchi-Sugita, A.5    Hori, H.6
  • 403
    • 84861374071 scopus 로고    scopus 로고
    • No association between the response to the addition of an atypical antipsychotic drug to an SSRI or SNRI and the BDNF (Val66Met) polymorphism in refractory major depressive disorder in Japanese patients
    • R. Yoshimura, T. Kishi, H. Hori, A. Ikenouchi-Sugita, W. Umene-Nakano, and A. Katsuki et al. No association between the response to the addition of an atypical antipsychotic drug to an SSRI or SNRI and the BDNF (Val66Met) polymorphism in refractory major depressive disorder in Japanese patients Clin Psychopharmacol Neurosci 10 2012 49 53
    • (2012) Clin Psychopharmacol Neurosci , vol.10 , pp. 49-53
    • Yoshimura, R.1    Kishi, T.2    Hori, H.3    Ikenouchi-Sugita, A.4    Umene-Nakano, W.5    Katsuki, A.6
  • 404
    • 0347415712 scopus 로고    scopus 로고
    • Therapeutic Applications of Selective and Non-Selective Inhibitors of Monoamine Oxidase A and B that do not Cause Significant Tyramine Potentiation
    • DOI 10.1016/S0161-813X(03)00103-7
    • M.B. Youdim, and M. Weinstock Therapeutic applications of selective and non-selective inhibitors of monoamine oxidase A and B that do not cause significant tyramine potentiation Neurotoxicology 25 2004 243 250 (Pubitemid 38044185)
    • (2004) NeuroToxicology , vol.25 , Issue.1-2 , pp. 243-250
    • Youdim, M.B.H.1    Weinstock, M.2
  • 405
    • 0036931893 scopus 로고    scopus 로고
    • Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders
    • DOI 10.1038/sj.mp.4001141
    • Y.W. Yu, S.J. Tsai, T.J. Chen, C.H. Lin, and C.J. Hong Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders Mol Psychiatry 7 2002 1115 1119 (Pubitemid 36044271)
    • (2002) Molecular Psychiatry , vol.7 , Issue.10 , pp. 1115-1119
    • Yu, Y.W.-Y.1    Tsai, S.-J.2    Chen, T.-J.3    Lin, C.-H.4    Hong, C.-J.5
  • 407
    • 27744436005 scopus 로고    scopus 로고
    • Association study of a Monoamine oxidase A gene promoter polymorphism with major depressive disorder and antidepressant response
    • DOI 10.1038/sj.npp.1300785, PII 1300785
    • Y.W. Yu, S.J. Tsai, C.J. Hong, T.J. Chen, M.C. Chen, and C.W. Yang Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response Neuropsychopharmacology 30 2005 1719 1723 (Pubitemid 43086029)
    • (2005) Neuropsychopharmacology , vol.30 , Issue.9 , pp. 1719-1723
    • Yu, Y.W.-Y.1    Tsai, S.-J.2    Hong, C.-J.3    Chen, T.-J.4    Chen, M.-C.5    Yang, C.-W.6
  • 408
    • 33748582618 scopus 로고    scopus 로고
    • Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders
    • DOI 10.1016/j.euroneuro.2005.12.004, PII S0924977X05002130
    • Y.W. Yu, S.J. Tsai, Y.J. Liou, C.J. Hong, and T.J. Chen Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders Eur Neuropsychopharmacol 16 2006 498 503 (Pubitemid 44376554)
    • (2006) European Neuropsychopharmacology , vol.16 , Issue.7 , pp. 498-503
    • Yu, Y.W.-Y.1    Tsai, S.-J.2    Liou, Y.-J.3    Hong, C.-J.4    Chen, T.-J.5
  • 409
    • 84863380672 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants
    • H. Yu, D.D. Wang, Y. Wang, T. Liu, F.S. Lee, and Z.Y. Chen Variant brain-derived neurotrophic factor Val66Met polymorphism alters vulnerability to stress and response to antidepressants J Neurosci 32 2012 4092 4101
    • (2012) J Neurosci , vol.32 , pp. 4092-4101
    • Yu, H.1    Wang, D.D.2    Wang, Y.3    Liu, T.4    Lee, F.S.5    Chen, Z.Y.6
  • 412
    • 3042722258 scopus 로고    scopus 로고
    • Tryptophan hydroxylase-2 controls brain synthesis
    • DOI 10.1126/science.1097540
    • X. Zhang, J.M. Beaulieu, T.D. Sotnikova, R.R. Gainetdinov, and M.G. Caron Tryptophan hydroxylase-2 controls brain serotonin synthesis Science 305 2004 217 (Pubitemid 38886729)
    • (2004) Science , vol.305 , Issue.5681 , pp. 217
    • Zhang, X.1    Beaulieu, J.-M.2    Sotnikova, T.D.3    Gainetdinov, R.R.4    Caron, M.G.5
  • 414
    • 80053503684 scopus 로고    scopus 로고
    • BDNF gene polymorphisms are associated with Alzheimer's disease-related depression and antidepressant response
    • L. Zhang, Y. Fang, Z. Zeng, Y. Lian, J. Wei, and H. Zhu et al. BDNF gene polymorphisms are associated with Alzheimer's disease-related depression and antidepressant response J Alzheimers Dis 26 2011 523 530
    • (2011) J Alzheimers Dis , vol.26 , pp. 523-530
    • Zhang, L.1    Fang, Y.2    Zeng, Z.3    Lian, Y.4    Wei, J.5    Zhu, H.6
  • 415
    • 33748365058 scopus 로고    scopus 로고
    • Response to Zhang et al. (2005): Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression
    • [Neuron. 2005; 48:702-3; author reply 5-6]
    • Z. Zhou, E.J. Peters, S.P. Hamilton, F. McMahon, C. Thomas, and P.J. McGrath et al. Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression Neuron 45 2005 11 16 [Neuron. 2005; 48:702-3; author reply 5-6]
    • (2005) Neuron , vol.45 , pp. 11-16
    • Zhou, Z.1    Peters, E.J.2    Hamilton, S.P.3    McMahon, F.4    Thomas, C.5    McGrath, P.J.6
  • 416
    • 64949159019 scopus 로고    scopus 로고
    • Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers
    • R. Zhou, P. Yuan, Y. Wang, J.G. Hunsberger, A. Elkahloun, and Y. Wei et al. Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers Neuropsychopharmacology 34 2009 1395 1405
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1395-1405
    • Zhou, R.1    Yuan, P.2    Wang, Y.3    Hunsberger, J.G.4    Elkahloun, A.5    Wei, Y.6
  • 417
    • 33750725388 scopus 로고    scopus 로고
    • Analysis of tryptophan hydroxylase I and II mRNA expression in the human brain: A post-mortem study
    • DOI 10.1016/j.jpsychires.2005.05.004, PII S0022395605000683
    • P. Zill, A. Buttner, W. Eisenmenger, H.J. Moller, M. Ackenheil, and B. Bondy Analysis of tryptophan hydroxylase I and II mRNA expression in the human brain: a post-mortem study J Psychiatr Res 41 2007 168 173 (Pubitemid 44708201)
    • (2007) Journal of Psychiatric Research , vol.41 , Issue.1-2 , pp. 168-173
    • Zill, P.1    Buttner, A.2    Eisenmenger, W.3    Moller, H.-J.4    Ackenheil, M.5    Bondy, B.6
  • 418
    • 72049090168 scopus 로고    scopus 로고
    • Association of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patients
    • Y.F. Zou, Y. Wang, P. Liu, X.L. Feng, B.Y. Wang, and T.H. Zang et al. Association of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patients Neuropsychobiology 61 2010 71 78
    • (2010) Neuropsychobiology , vol.61 , pp. 71-78
    • Zou, Y.F.1    Wang, Y.2    Liu, P.3    Feng, X.L.4    Wang, B.Y.5    Zang, T.H.6
  • 419
    • 77953962523 scopus 로고    scopus 로고
    • Meta-analysis of BDNF Val66Met polymorphism association with treatment response in patients with major depressive disorder
    • Y.F. Zou, D.Q. Ye, X.L. Feng, H. Su, F.M. Pan, and F.F. Liao Meta-analysis of BDNF Val66Met polymorphism association with treatment response in patients with major depressive disorder Eur Neuropsychopharmacol 20 2010 535 544
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 535-544
    • Zou, Y.F.1    Ye, D.Q.2    Feng, X.L.3    Su, H.4    Pan, F.M.5    Liao, F.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.