Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: Implications for clinical practice

American Journal of Psychiatry

Volumn 163, Issue 1, 2006, Pages 28-40

  Trivedi, Madhukar H ^a   Rush, A John ^b   Wisniewski, Stephen R ^b   Nierenberg, Andrew A ^b   Warden, Diane ^b   Ritz, Louise ^b   Norquist, Grayson ^b   Howland, Robert H ^b   Lebowitz, Barry ^b   McGrath, Patrick J ^b   Shores Wilson, Kathy ^b   Biggs, Melanie M ^b   Balasubramani, G K ^b   Fava, Maurizio ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPRAZOLAM; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; CITALOPRAM; NEUROLEPTIC AGENT; PSYCHOSTIMULANT AGENT; SEROTONIN UPTAKE INHIBITOR; TRAZODONE;

ADULT; ANXIETY DISORDER; ARTICLE; CAUCASIAN; CHRONIC DISEASE; CLINICAL PRACTICE; COMORBIDITY; DEPRESSION; DRUG ABUSE; EMPLOYMENT; FEMALE; HAMILTON SCALE; HUMAN; INCOME; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MENTAL DISEASE; MENTAL HEALTH CARE; NON INVASIVE MEASUREMENT; OUTPATIENT; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; QUALITY OF LIFE; QUICK INVENTORY OF DEPRESSIVE SYMPTOMATOLOGY SELF REPORT; REMISSION; SEX DIFFERENCE; SEXUAL DYSFUNCTION;

ADOLESCENT; AMBULATORY CARE; CHRONIC DISEASE; CITALOPRAM; COMORBIDITY; DEPRESSIVE DISORDER, MAJOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MENTAL DISORDERS; MIDDLE AGED; PERSONALITY INVENTORY; PSYCHIATRIC STATUS RATING SCALES; RECURRENCE; SEROTONIN UPTAKE INHIBITORS; TREATMENT OUTCOME;

EID: 30044433660     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.163.1.28     Document Type: Article

References (71)

1. Judd LL: Major depressive disorder: longitudinal symptomatic structure, relapse and recovery. Acta Psychiatr Scand 2001; 104:81-83
2. Nierenberg AA, Keefe BR, Leslie VC, Alpert JE, Pava JA, Worthington JJ, Fava M: Residual symptoms in depressed patients who respond acutely to fluoxetine. J Clin Psychiatry 1999; 60: 221-225
3. Paykel ES: Remission and residual symptomatology in major depression. Psychopathology 1998; 31:5-14
4. Depression Guideline Panel: Clinical Practice Guideline 5: Depression in Primary Care, vol 2: Treatment of Major Depression. Rockville, Md, US Department of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, 1993
5. Koran LM, Gelenberg AJ, Kornstein SG, Howland RH, Friedman RA, DeBattista C, Klein D, Kocsis JH, Schatzberg AF, Thase ME, Rush AJ, Hirschfeld RM, LaVange LM, Keller MB: Sertraline versus imipramine to prevent relapse in chronic depression. J Affect Disord 2001; 65:27-36
6. Paykel ES, Scott J, Teasdale JD, Johnson AL, Garland A, Moore R, Jenaway A, Cornwall PL, Hayhurst H, Abbott R, Pope M: Prevention of relapse in residual depression by cognitive therapy: a controlled trial. Arch Gen Psychiatry 1999; 56:829-835
7. Rush AJ, Fava M, Wisniewski SR, Lavori PW, Trivedi MH, Sackeim HA, Thase ME, Nierenberg AA, Quitkin FM, Kashner TM, Kupfer DJ, Rosenbaum JF, Alpert J, Stewart JW, McGrath PJ, Biggs MM, Shores-Wilson K, Lebowitz BD, Ritz L, Niederehe G: Sequenced Treatment Alternatives to Relieve Depression (STAR*D): rationale and design. Control Clin Trials 2004; 25:119-142
8. Keller MB, Gelenberg AJ, Hirschfeld RM, Rush AJ, Thase ME, Kocsis JH, Markowitz JC, Fawcett JA, Koran LM, Klein DN, Russell JM, Kornstein SG, McCullough JP, Davis SM, Harrison WM: The treatment of chronic depression, part 2: a double-blind, randomized trial of sertraline and imipramine. J Clin Psychiatry 1998; 59:598-607
9. Keller MB, McCullough JP, Klein DN, Arnow B, Dunner DL, Gelenberg AJ, Markowitz JC, Nemeroff CB, Russell JM, Thase ME, Trivedi MH, Zajecka J: A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression. N Engl J Med 2000; 342:1462-1470
10. Unützer J, Katon W, Callahan CM, Williams JW Jr, Hunkeler E, Harpole L, Hoffing M, Della Penna RD, Noel PH, Lin EH, Arean PA, Hegel MT, Tang L, Belin TR, Oishi S, Langston C: Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial. JAMA 2002; 288: 2836-2845
11. Rush AJ, Prien RF: From scientific knowledge to the clinical practice of psychopharmacology: can the gap be bridged? Psychopharmacol Bull 1995; 31:7-20
12. Kessler RC, Berglund P, Demler O, Jin R, Koretz D, Merikangas KR, Rush AJ, Walters EE, Wang PS: The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003; 289:3095-3105
13. Katon WJ, Von Korff M, Lin EH, Simon G, Ludman E, Russo J, Ciechanowski P, Walker E, Bush T: The Pathways Study: a randomized trial of collaborative care in patients with diabetes and depression. Arch Gen Psychiatry 2004; 61:1042-1049
14. Trivedi MH, Rush AJ, Crismon ML, Kashner TM, Toprac MG, Carmody TJ, Key T, Biggs MM, Shores-Wilson K, Witte B, Suppes T, Miller AL, Altshuler KZ, Shon SP: Clinical results for patients with major depressive disorder in the Texas Medication Algorithm Project. Arch Gen Psychiatry 2004; 61:669-680
15. Baron RM, Kenny DA: The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol 1986; 51: 1173-1182
16. Kraemer HC, Wilson T, Fairburn CG, Agras WS: Mediators and moderators of treatment effects in randomized controlled trials. Arch Gen Psychiatry 2002; 59:877-883
17. Bosworth HB, McQuoid DR, George LK, Steffens DC: Time-to-remission from geriatric depression: psychosocial and clinical factors. Am J Geriatr Psychiatry 2002; 10:551-559
18. Nierenberg AA: Predictors of response to antidepressants general principles and clinical implications. Psychiatr Clin North Am 2003; 26:345-352, viii
19. Bielski RJ, Friedel RO: Prediction of tricyclic antidepressant response: a critical review. Arch Gen Psychiatry 1976; 33:1479-1489
20. Croughan JL, Secunda SK, Katz MM, Robins E, Mendels J, Swann A, Harris-Larkin B: Sociodemographic and prior clinical course characteristics associated with treatment response in depressed patients. J Psychiatr Res 1988; 22:227-237
21. Greenhouse JB, Kupfer DJ, Frank E, Jarrett DB, Rejman KA: Analysis of time to stabilization in the treatment of depression: biological and clinical correlates. J Affect Disord 1987; 13:259-266
22. Hooley JM, Teasdale JD: Predictors of relapse in unipolar depressives: expressed emotion, marital distress, and perceived criticism. J Abnorm Psychol 1989; 98:229-235
23. Joyce PR, Paykel ES: Predictors of drug response in depression. Arch Gen Psychiatry 1989; 46:89-99
24. Katz MM, Koslow SH, Maas JW, Frazer A, Bowden CL, Casper R, Croughan J, Kocsis J, Redmond EJ: The timing, specificity and clinical prediction of tricyclic drug effects in depression. Psy-chol Med 1987; 17:297-309
25. Keller MB, Lavori PW, Mueller TI, Endicott J, Coryell W, Hirschfeld RM, Shea T: Time to recovery, chronicity, and levels of psychopathology in major depression: a 5-year prospective follow-up of 431 subjects. Arch Gen Psychiatry 1992; 49:809-816
26. Kocsis JH, Mason BJ, Frances AJ, Sweeney J, Mann JJ, Marin D: Prediction of response of chronic depression to imipramine. J Affect Disord 1989; 17:255-260
27. Vallejo J, Gasto C, Catalan R, Bulbena A, Menchon JM: Predictors of antidepressant treatment outcome in melancholia: psychosocial, clinical and biological indicators. J Affect Disord 1991; 21:151-162
28. Kocsis JH: New issues in the prediction of antidepressant response. Psychopharmacol Bull 1990; 26:49-53
29. Brugha TS, Bebbington PE, MacCarthy B, Sturt E, Wykes T, Potter J: Gender, social support and recovery from depressive disorders: a prospective clinical study. Psychol Med 1990; 20:147-156
30. Goodwin FK: Predictors of antidepressant response. Bull Menninger Clin 1993; 57:146-160
31. Hoencamp E, Haffmans PM, Duivenvoorden H, Knegtering H, Dijken WA: Predictors of (non-) response in depressed outpatients treated with a three-phase sequential medication strategy. J Affect Disord 1994; 31:235-246
32. Friedman RA, Parides M, Baff R, Moran M, Kocsis JH: Predictors of response to desipramine in dysthymia. J Clin Psychopharmacol 1995; 15:280-283
33. Cohn CK, Robinson DS, Roberts DL, Schwiderski UE, O'Brien K, leni JR: Responders to antidepressant drug treatment: a study comparing nefazodone, imipramine, and placebo in patients with major depression. J Clin Psychiatry 1996; 57(suppl 2):15-18
34. Esposito K, Goodnick P: Predictors of response in depression. Psychiatr Clin North Am 2003; 26:353-365
35. Aliapoulous J, Zisook S: Tricyclic antidepressant medications, in Predictors of Treatment Response in Mood Disorders. Edited by Goodnick PJ. Washington, DC, American Psychiatric Press, 1996, pp 1-36
36. Fava M, Rush AJ, Trivedi MH, Nierenberg AA, Thase ME, Sackeim HA, Quitkin FM, Wisniewski S, Lavori PW, Rosenbaum JF, Kupfer DJ: Background and rationale for the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study. Psychiatr Clin North Am 2003; 26:457-494
37. Hamilton M: A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62
38. Hamilton M: Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967; 6:278-296
39. Zimmerman M, Mattia JI: A self-report scale to help make psychiatric diagnoses: the Psychiatric Diagnostic Screening Questionnaire. Arch Gen Psychiatry 2001; 58:787-794
40. Zimmerman M, Mattia JI: The Psychiatric Diagnostic Screening Questionnaire: development, reliability and validity. Compr Psychiatry 2001; 42:175-189
41. Rush AJ, Zimmerman M, Wisniewski SR, Fava M, Hollon SD, Warden D, Biggs MM, Shores-Wilson K, Shelton RC, Luther JF, Thomas B, Trivedi MH: Comorbid psychiatric disorders in depressed outpatients: demographic and clinical features. J Affect Disord 2005; 87:43-55
42. Novick JS, Stewart JW, Wisniewski SR, Cook IA, Manev R, Nierenberg AA, Rosenbaum JF, Shores-Wilson K, Balasubramani GK, Biggs MM, Zisook S, Rush AJ (STAR*D investigators): Clinical and demographic features of atypical depression in outpatients with major depression: preliminary findings from STAR*D. J Clin Psychiatry 2005; 66:1002-1011
43. Fava M, Alpert JE, Carmin CN, Wisniewski SR, Trivedi MH, Biggs MM, Shores-Wilson K, Morgan D, Schwartz T, Balasubramani GK, Rush AJ: Clinical correlates and symptom patterns of anxious depression among patients with major depressive disorder in STAR*D. Psychol Med 2004; 34:1299-1308
44. Khan AY, Carrithers J, Preskorn SH, Wisniewski SR, Lear R, Rush AJ, Stegman D, Kelley C, Kreiner K, Nierenberg AA, Fava M: Clinical and demographic factors associated with DSM-IV melancholic depression. Ann Clin Psychiatry (in press)
45. Rush AJ, Trivedi MH, Ibrahim HM, Carmody TJ, Arnow B, Klein DN, Markowitz JC, Ninan PT, Kornstein S, Manber R, Thase ME, Kocsis JH, Keller MB: The 16-item Quick Inventory of Depressive Symptomatology (QIDS), Clinician Rating (QIDS-C), and Self-Report (QIDS-SR): a psychometric evaluation in patients with chronic major depression. Biol Psychiatry 2003; 54:573-583
46. Trivedi MH, Rush AJ, Ibrahim HM, Carmody TJ, Biggs MM, Suppes T, Crismon ML, Shores-Wilson K, Toprac MG, Dennehy EB, Witte B, Kashner TM: The Inventory of Depressive Symptomatology, Clinician Rating (IDS-C) and Self-Report (IDS-SR), and the Quick Inventory of Depressive Symptomatology, Clinician Rating (QIDS-C) and Self-Report (QIDS-SR) in public sector patients with mood disorders: a psychometric evaluation. Psychol Med 2004; 34:73-82
47. Rush AJ, Bernstein IH, Trivedi MH, Carmody TJ, Wisniewski S, Mundt JC, Shores-Wilson K, Biggs MM, Woo A, Nierenberg AA, Fava M: An evaluation of the Quick Inventory of Depressive Symptomatology and the Hamilton Rating Scale for Depression: a Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial report. Biol Psychiatry (in press)
48. Linn BS, Linn MW, Gurel L: Cumulative Illness Rating Scale. J Am Geriatr Soc 1968; 16:622-626
49. Miller MD, Paradis CF, Houck PR, Mazumdar S, Stack JA, Rifai AH, Mulsant B, Reynolds CF III: Rating chronic medical illness burden in geropsychiatric practice and research: application of the Cumulative Illness Rating Scale. Psychiatry Res 1992; 41:237-248
50. Kobak KA, Greist JH, Jefferson JW, Mundt JC, Katzelnick DJ: Computerized assessment of depression and anxiety over the telephone using interactive voice response. MD Comput 1999; 16: 63-68
51. Mundt JC: Interactive voice response systems in clinical research and treatment. Psychiatr Serv 1997; 48:611-612
52. Trivedi MH, Rush AJ, Wisniewski SR, Warden D, McKinney W, Downing M, Berman SR, Farabaugh A, Luther J, Nierenberg AA, Lis J, Sackeim H: Factors associated with health-related quality of life among outpatients with major depressive disorder: a STAR*D report. J Clin Psychiatry (in press)
53. Ware J Jr, Kosinski M, Keller SD: A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care 1996; 34:220-233
54. Endicott J, Nee J, Harrison W, Blumenthal R: Quality of Life Enjoyment and Satisfaction Questionnaire: a new measure. Psychopharmacol Bull 1993; 29:321-326
55. Mundt JC, Marks IM, Shear MK, Greist JH: The Work and Social Adjustment Scale: a simple measure of impairment in functioning. Br J Psychiatry 2002; 180:461-464
56. Reilly MC, Zbrozek AS, Dukes EM: The validity and reproducibility of a work productivity and activity impairment instrument. Pharmacoeconomics 1993; 4:353-365
57. Nierenberg AA, Trivedi MH, Ritz L, Burroughs D, Greist J, Sackeim H, Kornstein S, Schwartz T, Stegman D, Fava M, Wisniewski SR: Suicide risk management for the Sequenced Treatment Alternatives to Relieve Depression study: applied NIMH guidelines. J Psychiatr Res 2004; 38:583-589
58. Posternak MA, Zimmerman M, Keitner GI, Miller IW: A reevaluation of the exclusion criteria used in antidepressant efficacy trials. Am J Psychiatry 2002; 159:191-200
59. Rapaport MH, Pollack M, Wolkow R, Mardekian J, Clary C: Is placebo response the same as drug response in panic disorder? Am J Psychiatry 2000; 157:1014-1016
60. Zimmerman M, Chelminski I, Posternak MA: Exclusion criteria used in antidepressant efficacy trials: consistency across studies and representativeness of samples included. J Nerv Ment Dis 2004; 192:87-94
61. Zimmerman M, Chelminski I, Posternak MA: Generalizability of antidepressant efficacy trials: differences between depressed psychiatric outpatients who would or would not qualify for an efficacy trial. Am J Psychiatry 2005; 162:1370-1372
62. Hunkeler EM, Meresman JF, Hargreaves WA, Fireman B, Berman WH, Kirsch AJ, Groebe J, Hurt SW, Braden P, Getzell M, Feigenbaum PA, Peng T, Salzer M: Efficacy of nurse telehealth care and peer support in augmenting treatment of depression in primary care. Arch Fam Med 2000; 9:700-708
63. Hirschfeld RM, Montgomery SA, Aguglia E, Amore M, Delgado PL, Gastpar M, Hawley C, Kasper S, Linden M, Massana J, Mendlewiczj, Moller HJ, Nemeroff CB, Saiz J, Such P, Torta R, Versiani M: Partial response and nonresponse to antidepressant therapy: current approaches and treatment options. J Clin Psychiatry 2002; 63:826-837
64. Keller MB, Klerman GL, Lavori PW, Coryell W, Endicott J, Taylor J: Long-term outcome of episodes of major depression, clinical and public health significance. JAMA 1984; 252:788-792
65. Rush AJ, Roffwarg HP, Giles DE, Schlesser MA, Fairchild C, Tarell J: Psychobiological predictors of antidepressant drug response. Pharmacopsychiatria 1983; 16:192-194
66. Fava M, Uebelacker LA, Alpert JE, Nierenberg AA, Pava JA, Rosenbaum JF: Major depressive subtypes and treatment response. Biol Psychiatry 1997; 42:568-576
67. Iosifescu DV, Nierenberg AA, Alpert JE, Smith M, Bitran S, Dording C, Fava M: The impact of medical comorbidity on acute treatment in major depressive disorder. Am J Psychiatry 2003; 160:2122-2127
68. Hagerty BM, Williams RA: The effects of sense of belonging, social support, conflict, and loneliness on depression. Nurs Res 1999; 48:215-219
69. George LK, Blazer DG, Hughes DC, Fowler N: Social support and the outcome of major depression. Br J Psychiatry 1989; 154: 478-485
70. Hirschfeld RM, Klerman GL, Andreasen NC, Clayton PJ, Keller MB: Psycho-social predictors of chronicity in depressed patients. Br J Psychiatry 1986; 148:648-654
71. Khan A, Leventhal RM, Khan SR, Brown WA: Severity of depression and response to antidepressants and placebo: an analysis of the Food and Drug Administration database. J Clin Psychopharmacol 2002; 22:40-45