메뉴 건너뛰기




Volumn 21, Issue C, 2010, Pages 749-789

The Behavioral Genetics of Serotonin: Relevance to Anxiety and Depression

Author keywords

5 HT; antidepressant; genetically modified mouse; knockout; SERT; single nucleotide polymorphism; TPH2; tryptophan

Indexed keywords


EID: 79251593587     PISSN: 15697339     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1569-7339(10)70109-0     Document Type: Chapter
Times cited : (17)

References (409)
  • 2
    • 33745000987 scopus 로고    scopus 로고
    • Early life blockade of 5-hydroxytryptamine 1A receptors normalizes sleep and depression-like behavior in adult knockout mice lacking the serotonin transporter
    • C. Alexandre D. Popa V. Fabre S. Bouali P. Venault K.P. Lesch M. Hamon J. Adrien Early life blockade of 5-hydroxytryptamine 1A receptors normalizes sleep and depression-like behavior in adult knockout mice lacking the serotonin transporter J. Neurosci. 26 2006 5554 5564
    • (2006) J. Neurosci. , vol.26 , pp. 5554-5564
    • Alexandre, C.1    Popa, D.2    Fabre, V.3    Bouali, S.4    Venault, P.5    Lesch, K.P.6    Hamon, M.7    Adrien, J.8
  • 3
    • 0034789503 scopus 로고    scopus 로고
    • Conditioned place preference for cocaine is attenuated in mice over-expressing the 5-HT(3) receptor
    • A.M. Allan R. Galindo J. Chynoweth S.R. Engel D.D. Savage Conditioned place preference for cocaine is attenuated in mice over-expressing the 5-HT(3) receptor Psychopharmacology (Berl.) 158 2001 18 27
    • (2001) Psychopharmacology (Berl.) , vol.158 , pp. 18-27
    • Allan, A.M.1    Galindo, R.2    Chynoweth, J.3    Engel, S.R.4    Savage, D.D.5
  • 4
    • 0041346384 scopus 로고    scopus 로고
    • A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I
    • M. Anguelova C. Benkelfat G. Turecki A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I Affective disorders. Mol. Psychiatry 8 2003 574 591
    • (2003) Affective disorders. Mol. Psychiatry , vol.8 , pp. 574-591
    • Anguelova, M.1    Benkelfat, C.2    Turecki, G.3
  • 5
    • 38149041752 scopus 로고    scopus 로고
    • Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice
    • M.S. Ansorge E. Morelli J.A. Gingrich Inhibition of serotonin but not norepinephrine transport during development produces delayed, persistent perturbations of emotional behaviors in mice J. Neurosci. 28 2008 199 207
    • (2008) J. Neurosci. , vol.28 , pp. 199-207
    • Ansorge, M.S.1    Morelli, E.2    Gingrich, J.A.3
  • 6
    • 7444232259 scopus 로고    scopus 로고
    • Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice
    • M.S. Ansorge M. Zhou A. Lira R. Hen J.A. Gingrich Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice Science 306 2004 879 881
    • (2004) Science , vol.306 , pp. 879-881
    • Ansorge, M.S.1    Zhou, M.2    Lira, A.3    Hen, R.4    Gingrich, J.A.5
  • 8
    • 0032444370 scopus 로고    scopus 로고
    • Global increases in seizure susceptibility in mice lacking 5-HT2C receptors: a behavioral analysis
    • 2C receptors: a behavioral analysis Exp. Neurol. 154 1998 522 530
    • (1998) Exp. Neurol. , vol.154 , pp. 522-530
    • Applegate, C.D.1    Tecott, L.H.2
  • 9
    • 0035118631 scopus 로고    scopus 로고
    • Variability in the 5-HT(2A) receptor gene is associated with seasonal pattern in major depression
    • B. Arias B. Gutierrez L. Pintor C. Gasto L. Fananas Variability in the 5-HT(2A) receptor gene is associated with seasonal pattern in major depression Mol. Psychiatry 6 2001 239 242
    • (2001) Mol. Psychiatry , vol.6 , pp. 239-242
    • Arias, B.1    Gutierrez, B.2    Pintor, L.3    Gasto, C.4    Fananas, L.5
  • 10
    • 0035829971 scopus 로고    scopus 로고
    • The 5-HT(2A) receptor gene 102T/C polymorphism is associated with suicidal behavior in depressed patients
    • B. Arias C. Gasto R. Catalan B. Gutierrez L. Pintor L. Fananas The 5-HT(2A) receptor gene 102T/C polymorphism is associated with suicidal behavior in depressed patients Am. J. Med. Genet. 105 2001 801 804
    • (2001) Am. J. Med. Genet. , vol.105 , pp. 801-804
    • Arias, B.1    Gasto, C.2    Catalan, R.3    Gutierrez, B.4    Pintor, L.5    Fananas, L.6
  • 12
    • 17744397364 scopus 로고    scopus 로고
    • Evidence for a combined genetic effect of the 5-HT(1A) receptor and serotonin transporter genes in the clinical outcome of major depressive patients treated with citalopram
    • B. Arias R. Catalan C. Gasto B. Gutierrez L. Fananas Evidence for a combined genetic effect of the 5-HT(1A) receptor and serotonin transporter genes in the clinical outcome of major depressive patients treated with citalopram J. Psychopharmacol. 19 2005 166 172
    • (2005) J. Psychopharmacol. , vol.19 , pp. 166-172
    • Arias, B.1    Catalan, R.2    Gasto, C.3    Gutierrez, B.4    Fananas, L.5
  • 14
    • 0018200286 scopus 로고
    • An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat
    • E.C. Azmitia M. Segal An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat J. Comp. Neurol. 179 1978 641 667
    • (1978) J. Comp. Neurol. , vol.179 , pp. 641-667
    • Azmitia, E.C.1    Segal, M.2
  • 18
    • 0032970989 scopus 로고    scopus 로고
    • A review of central 5-HT receptors and their function
    • N.M. Barnes T. Sharp A review of central 5-HT receptors and their function Neuropharmacology 38 1999 1083 1152
    • (1999) Neuropharmacology , vol.38 , pp. 1083-1152
    • Barnes, N.M.1    Sharp, T.2
  • 19
    • 41949102371 scopus 로고    scopus 로고
    • Serotonin receptor 1A-1019C/G variant: impact on antidepressant pharmacoresponse in melancholic depression?
    • B.T. Baune C. Hohoff T. Roehrs J. Deckert V. Arolt K. Domschke Serotonin receptor 1A-1019C/G variant: impact on antidepressant pharmacoresponse in melancholic depression? Neurosci. Lett. 436 2008 111 115
    • (2008) Neurosci. Lett. , vol.436 , pp. 111-115
    • Baune, B.T.1    Hohoff, C.2    Roehrs, T.3    Deckert, J.4    Arolt, V.5    Domschke, K.6
  • 23
    • 0347993742 scopus 로고    scopus 로고
    • Association between the TPH gene A218C polymorphism and suicidal behavior: a meta-analysis
    • F. Bellivier P. Chaste A. Malafosse Association between the TPH gene A218C polymorphism and suicidal behavior: a meta-analysis Am. J. Med. Genet. B Neuropsychiatr. Genet. 124B 2004 87 91
    • (2004) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.124B , pp. 87-91
    • Bellivier, F.1    Chaste, P.2    Malafosse, A.3
  • 24
    • 0035829390 scopus 로고    scopus 로고
    • Measuring normal and pathological anxiety-like behavior in mice: a review
    • C. Belzung G. Griebel Measuring normal and pathological anxiety-like behavior in mice: a review Behav. Brain Res. 125 2001 141 149
    • (2001) Behav. Brain Res. , vol.125 , pp. 141-149
    • Belzung, C.1    Griebel, G.2
  • 25
    • 0142072078 scopus 로고    scopus 로고
    • Antidepressant effects of light therapy combined with sleep deprivation are influenced by a functional polymorphism within the promoter of the serotonin transporter gene
    • F. Benedetti C. Colombo A. Serretti C. Lorenzi A. Pontiggia B. Barbini E. Smeraldi Antidepressant effects of light therapy combined with sleep deprivation are influenced by a functional polymorphism within the promoter of the serotonin transporter gene Biol. Psychiatry 54 2003 687 692
    • (2003) Biol. Psychiatry , vol.54 , pp. 687-692
    • Benedetti, F.1    Colombo, C.2    Serretti, A.3    Lorenzi, C.4    Pontiggia, A.5    Barbini, B.6    Smeraldi, E.7
  • 28
    • 30744436816 scopus 로고    scopus 로고
    • Mice over-expressing the 5-HT(1A) receptor in cortex and dentate gyrus display exaggerated locomotor and hypothermic response to 8-OH-DPAT
    • B. Bert H. Fink H. Hortnagl R.W. Veh B. Davies F. Theuring H. Kusserow Mice over-expressing the 5-HT(1A) receptor in cortex and dentate gyrus display exaggerated locomotor and hypothermic response to 8-OH-DPAT Behav. Brain Res. 167 2006 328 341
    • (2006) Behav. Brain Res. , vol.167 , pp. 328-341
    • Bert, B.1    Fink, H.2    Hortnagl, H.3    Veh, R.W.4    Davies, B.5    Theuring, F.6    Kusserow, H.7
  • 29
    • 3242699529 scopus 로고    scopus 로고
    • Deletion of the 5-HT3 receptor differentially affects behavior of males and females in the Porsolt forced swim and defensive withdrawal tests
    • 3 receptor differentially affects behavior of males and females in the Porsolt forced swim and defensive withdrawal tests Behav. Brain Res. 153 2004 527 535
    • (2004) Behav. Brain Res. , vol.153 , pp. 527-535
    • Bhatnagar, S.1    Nowak, N.2    Babich, L.3    Bok, L.4
  • 30
    • 2642511290 scopus 로고    scopus 로고
    • Changes in anxiety-related behaviors and hypothalamic-pituitary-adrenal activity in mice lacking the 5-HT-3A receptor
    • S. Bhatnagar L.M. Sun J. Raber S. Maren D. Julius M.F. Dallman Changes in anxiety-related behaviors and hypothalamic-pituitary-adrenal activity in mice lacking the 5-HT-3A receptor Physiol. Behav. 81 2004 545 555
    • (2004) Physiol. Behav. , vol.81 , pp. 545-555
    • Bhatnagar, S.1    Sun, L.M.2    Raber, J.3    Maren, S.4    Julius, D.5    Dallman, M.F.6
  • 31
    • 0031228024 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder, response to serotonin reuptake inhibitors and the serotonin transporter gene
    • E.A. Billett M.A. Richter N. King A. Heils K.P. Lesch J.L. Kennedy Obsessive-compulsive disorder, response to serotonin reuptake inhibitors and the serotonin transporter gene Mol. Psychiatry 2 1997 403 406
    • (1997) Mol. Psychiatry , vol.2 , pp. 403-406
    • Billett, E.A.1    Richter, M.A.2    King, N.3    Heils, A.4    Lesch, K.P.5    Kennedy, J.L.6
  • 34
    • 24044460136 scopus 로고    scopus 로고
    • Biogenic amine neurotransmitter transporters: just when you thought you knew them
    • R.D. Blakely L.J. Defelice A. Galli Biogenic amine neurotransmitter transporters: just when you thought you knew them Physiology (Beth MD) 20 2005 225 231
    • (2005) Physiology (Beth MD) , vol.20 , pp. 225-231
    • Blakely, R.D.1    Defelice, L.J.2    Galli, A.3
  • 36
    • 0000261111 scopus 로고    scopus 로고
    • 5-HT4 receptors: an update
    • 4 receptors: an update H.G. Baumgarten M. Gothert Serotoninergic Neurons and 5-HT Receptors in the CNS 1997 Springer Berlin 239 268
    • (1997) , pp. 239-268
    • Bockaert, J.1    Fagni, L.2    Dumuis, A.3
  • 37
    • 33748943679 scopus 로고    scopus 로고
    • Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation
    • J. Bockaert S. Claeysen C. Becamel A. Dumuis P. Marin Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation Cell Tissue Res. 326 2006 553 572
    • (2006) Cell Tissue Res. , vol.326 , pp. 553-572
    • Bockaert, J.1    Claeysen, S.2    Becamel, C.3    Dumuis, A.4    Marin, P.5
  • 38
    • 34247270861 scopus 로고    scopus 로고
    • Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents
    • P. Bonaventure L. Kelly L. Aluisio J. Shelton B. Lord R. Galici K. Miller J. Atack T.W. Lovenberg C. Dugovic Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents J. Pharmacol. Exp. Ther. 321 2007 690 698
    • (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 690-698
    • Bonaventure, P.1    Kelly, L.2    Aluisio, L.3    Shelton, J.4    Lord, B.5    Galici, R.6    Miller, K.7    Atack, J.8    Lovenberg, T.W.9    Dugovic, C.10
  • 39
    • 0036570263 scopus 로고    scopus 로고
    • Association of 5-HT(2A) receptor gene polymorphism with major affective disorders: the case of a subgroup of bipolar disorder with low suicide risk
    • B. Bonnier P. Gorwood M. Hamon Y. Sarfati C. Boni M.C. Hardy-Bayle Association of 5-HT(2A) receptor gene polymorphism with major affective disorders: the case of a subgroup of bipolar disorder with low suicide risk Biol. Psychiatry 51 2002 762 765
    • (2002) Biol. Psychiatry , vol.51 , pp. 762-765
    • Bonnier, B.1    Gorwood, P.2    Hamon, M.3    Sarfati, Y.4    Boni, C.5    Hardy-Bayle, M.C.6
  • 41
    • 0036616839 scopus 로고    scopus 로고
    • Involvement of 5-HT1A receptors in homeostatic and stress-induced adaptive regulations of paradoxical sleep: studies in 5-HT1A knockout mice
    • B. Boutrel C. Monaca R. Hen M. Hamon J. Adrien Involvement of 5-HT1A receptors in homeostatic and stress-induced adaptive regulations of paradoxical sleep: studies in 5-HT1A knockout mice J. Neurosci. 22 2002 4686 4692
    • (2002) J. Neurosci. , vol.22 , pp. 4686-4692
    • Boutrel, B.1    Monaca, C.2    Hen, R.3    Hamon, M.4    Adrien, J.5
  • 43
    • 0035312517 scopus 로고    scopus 로고
    • Absence of 5-HT(1B) receptors is associated with impaired impulse control in male 5-HT(1B) knockout mice
    • J.A. Bouwknecht T.H. Hijzen J. van der Gugten R.A. Maes R. Hen B. Olivier Absence of 5-HT(1B) receptors is associated with impaired impulse control in male 5-HT(1B) knockout mice Biol. Psychiatry 49 2001 557 568
    • (2001) Biol. Psychiatry , vol.49 , pp. 557-568
    • Bouwknecht, J.A.1    Hijzen, T.H.2    van der Gugten, J.3    Maes, R.A.4    Hen, R.5    Olivier, B.6
  • 45
    • 72449155342 scopus 로고    scopus 로고
    • Association study of paroxetine therapeutic response with SERT gene polymorphisms in patients with major depressive disorder
    • N. Bozina A.M. Peles M. Sagud H. Bilusic M. Jakovljevic Association study of paroxetine therapeutic response with SERT gene polymorphisms in patients with major depressive disorder World J. Biol. Psychiatry 2007 1 8
    • (2007) World J. Biol. Psychiatry , pp. 1-8
    • Bozina, N.1    Peles, A.M.2    Sagud, M.3    Bilusic, H.4    Jakovljevic, M.5
  • 48
    • 38649105517 scopus 로고    scopus 로고
    • Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR)
    • B.H. Brummett S.H. Boyle I.C. Siegler C.M. Kuhn A. Ashley-Koch C.R. Jonassaint S. Zuchner A. Collins R.B. Williams Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR) Behav. Genet. 38 2008 34 43
    • (2008) Behav. Genet. , vol.38 , pp. 34-43
    • Brummett, B.H.1    Boyle, S.H.2    Siegler, I.C.3    Kuhn, C.M.4    Ashley-Koch, A.5    Jonassaint, C.R.6    Zuchner, S.7    Collins, A.8    Williams, R.B.9
  • 50
    • 0027442475 scopus 로고
    • Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A
    • H.G. Brunner M. Nelen X.O. Breakefield H.H. Ropers B.A. van Oost Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A Science 262 1993 578 580
    • (1993) Science , vol.262 , pp. 578-580
    • Brunner, H.G.1    Nelen, M.2    Breakefield, X.O.3    Ropers, H.H.4    van Oost, B.A.5
  • 52
    • 0345170675 scopus 로고    scopus 로고
    • Spatial learning in the 5-HT1B receptor knockout mouse: selective facilitation/impairment depending on the cognitive demand
    • 1B receptor knockout mouse: selective facilitation/impairment depending on the cognitive demand Learn. Mem. 10 2003 466 477
    • (2003) Learn. Mem. , vol.10 , pp. 466-477
    • Buhot, M.C.1    Wolff, M.2    Benhassine, N.3    Costet, P.4    Hen, R.5    Segu, L.6
  • 60
    • 23744490895 scopus 로고    scopus 로고
    • Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: a systematic review and meta-analysis
    • H.J. Cho I. Meira-Lima Q. Cordeiro L. Michelon P. Sham H. Vallada D.A. Collier Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: a systematic review and meta-analysis Mol. Psychiatry 10 2005 771 781
    • (2005) Mol. Psychiatry , vol.10 , pp. 771-781
    • Cho, H.J.1    Meira-Lima, I.2    Cordeiro, Q.3    Michelon, L.4    Sham, P.5    Vallada, H.6    Collier, D.A.7
  • 61
    • 1642496848 scopus 로고    scopus 로고
    • Association between major depressive disorder and the -1438A/G polymorphism of the serotonin 2A receptor gene
    • M.J. Choi H.J. Lee B.J. Ham J.H. Cha S.H. Ryu M.S. Lee Association between major depressive disorder and the -1438A/G polymorphism of the serotonin 2A receptor gene Neuropsychobiology 49 2004 38 41
    • (2004) Neuropsychobiology , vol.49 , pp. 38-41
    • Choi, M.J.1    Lee, H.J.2    Ham, B.J.3    Cha, J.H.4    Ryu, S.H.5    Lee, M.S.6
  • 64
    • 33846058030 scopus 로고    scopus 로고
    • Candidate gene polymorphisms in the serotonergic pathway: influence on depression symptomatology in an elderly population
    • L. Christiansen Q. Tan M. Iachina L. Bathum T.A. Kruse M. McGue K. Christensen Candidate gene polymorphisms in the serotonergic pathway: influence on depression symptomatology in an elderly population Biol. Psychiatry 61 2007 223 230
    • (2007) Biol. Psychiatry , vol.61 , pp. 223-230
    • Christiansen, L.1    Tan, Q.2    Iachina, M.3    Bathum, L.4    Kruse, T.A.5    McGue, M.6    Christensen, K.7
  • 66
    • 0036618224 scopus 로고    scopus 로고
    • Overexpression of 5-HT1B receptor in dorsal raphe nucleus using Herpes Simplex Virus gene transfer increases anxiety behavior after inescapable stress
    • 1B receptor in dorsal raphe nucleus using Herpes Simplex Virus gene transfer increases anxiety behavior after inescapable stress J. Neurosci. 22 2002 4550 4562
    • (2002) J. Neurosci. , vol.22 , pp. 4550-4562
    • Clark, M.S.1    Sexton, T.J.2    McClain, M.3    Root, D.4    Kohen, R.5    Neumaier, J.F.6
  • 67
    • 1942439034 scopus 로고    scopus 로고
    • Increased expression of 5-HT1B receptor in dorsal raphe nucleus decreases fear-potentiated startle in a stress dependent manner
    • 1B receptor in dorsal raphe nucleus decreases fear-potentiated startle in a stress dependent manner Brain Res. 1007 2004 86 97
    • (2004) Brain Res. , vol.1007 , pp. 86-97
    • Clark, M.S.1    Vincow, E.S.2    Sexton, T.J.3    Neumaier, J.F.4
  • 71
    • 0029092406 scopus 로고
    • No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms
    • N. Craddock J. Daniels E. Roberts M. Rees P. McGuffin M.J. Owen No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms Am. J. Med. Genet. 60 1995 322 324
    • (1995) Am. J. Med. Genet. , vol.60 , pp. 322-324
    • Craddock, N.1    Daniels, J.2    Roberts, E.3    Rees, M.4    McGuffin, P.5    Owen, M.J.6
  • 74
    • 27744571293 scopus 로고    scopus 로고
    • Strain-dependent antidepressant-like effects of citalopram in the mouse tail suspension test
    • J.J. Crowley J.A. Blendy I. Lucki Strain-dependent antidepressant-like effects of citalopram in the mouse tail suspension test Psychopharmacology (Berl.) 183 2005 257 264
    • (2005) Psychopharmacology (Berl.) , vol.183 , pp. 257-264
    • Crowley, J.J.1    Blendy, J.A.2    Lucki, I.3
  • 75
    • 0034074370 scopus 로고    scopus 로고
    • 5-HT1A and beyond: the role of serotonin and its receptors in depression and the antidepressant response
    • J.F. Cryan B.E. Leonard 5-HT1A and beyond: the role of serotonin and its receptors in depression and the antidepressant response Hum. Psychopharmacol. 15 2000 113 135
    • (2000) Hum. Psychopharmacol. , vol.15 , pp. 113-135
    • Cryan, J.F.1    Leonard, B.E.2
  • 76
    • 0033681079 scopus 로고    scopus 로고
    • Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors
    • J.F. Cryan I. Lucki Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors J. Pharmacol. Exp. Ther. 295 2000 1120 1126
    • (2000) J. Pharmacol. Exp. Ther. , vol.295 , pp. 1120-1126
    • Cryan, J.F.1    Lucki, I.2
  • 78
    • 0013774096 scopus 로고
    • Localization of monoamines in the lower brain stem
    • A. Dahlstrom K. Fuxe Localization of monoamines in the lower brain stem Experientia 20 1964 398 399
    • (1964) Experientia , vol.20 , pp. 398-399
    • Dahlstrom, A.1    Fuxe, K.2
  • 84
    • 0026005750 scopus 로고
    • Rapid serotonin depletion as a provocative challenge test for patients with major depression: relevance to antidepressant action and the neurobiology of depression
    • P.L. Delgado L.H. Price H.L. Miller R.M. Salomon J. Licinio J.H. Krystal G.R. Heninger D.S. Charney Rapid serotonin depletion as a provocative challenge test for patients with major depression: relevance to antidepressant action and the neurobiology of depression Psychopharmacol. Bull. 27 1991 321 330
    • (1991) Psychopharmacol. Bull. , vol.27 , pp. 321-330
    • Delgado, P.L.1    Price, L.H.2    Miller, H.L.3    Salomon, R.M.4    Licinio, J.5    Krystal, J.H.6    Heninger, G.R.7    Charney, D.S.8
  • 86
    • 32844473728 scopus 로고    scopus 로고
    • Association between serotonergic candidate genes and specific phenotypes of obsessive-compulsive disorder
    • D. Denys F. Van Nieuwerburgh D. Deforce H.G. Westenberg Association between serotonergic candidate genes and specific phenotypes of obsessive-compulsive disorder J. Affect. Disord. 91 2006 39 44
    • (2006) J. Affect. Disord. , vol.91 , pp. 39-44
    • Denys, D.1    Van Nieuwerburgh, F.2    Deforce, D.3    Westenberg, H.G.4
  • 87
    • 34249738697 scopus 로고    scopus 로고
    • Prediction of response to paroxetine and venlafaxine by serotonin-related genes in obsessive-compulsive disorder in a randomized, double-blind trial
    • D. Denys F. Van Nieuwerburgh D. Deforce H.G. Westenberg Prediction of response to paroxetine and venlafaxine by serotonin-related genes in obsessive-compulsive disorder in a randomized, double-blind trial J. Clin. Psychiatry 68 2007 747 753
    • (2007) J. Clin. Psychiatry , vol.68 , pp. 747-753
    • Denys, D.1    Van Nieuwerburgh, F.2    Deforce, D.3    Westenberg, H.G.4
  • 91
  • 92
    • 34447504043 scopus 로고    scopus 로고
    • Increased risk for major depression associated with the short allele of the serotonin transporter promoter region (5-HTTLPR-S) and the CYP2C9*3 allele
    • P. Dorado E.M. Penas-Lledo A.P. Gonzalez M.C. Caceres J. Cobaleda A. Llerena Increased risk for major depression associated with the short allele of the serotonin transporter promoter region (5-HTTLPR-S) and the CYP2C9*3 allele Fundam. Clin. Pharmacol. 21 2007 451 453
    • (2007) Fundam. Clin. Pharmacol. , vol.21 , pp. 451-453
    • Dorado, P.1    Penas-Lledo, E.M.2    Gonzalez, A.P.3    Caceres, M.C.4    Cobaleda, J.5    Llerena, A.6
  • 93
    • 0035003890 scopus 로고    scopus 로고
    • Tryptophan hydroxylase gene 218A/C polymorphism is associated with somatic anxiety in major depressive disorder
    • L. Du D. Bakish P.D. Hrdina Tryptophan hydroxylase gene 218A/C polymorphism is associated with somatic anxiety in major depressive disorder J. Affect. Disord. 65 2001 37 44
    • (2001) J. Affect. Disord. , vol.65 , pp. 37-44
    • Du, L.1    Bakish, D.2    Hrdina, P.D.3
  • 94
    • 33645468075 scopus 로고    scopus 로고
    • Acquisition and extinction of a conditioned passive avoidance reflex in mice with genetic knockout of monoamine oxidase A
    • N.I. Dubrovina N.K. Popova M.A. Gilinskii R.A. Tomilenko I. Seif Acquisition and extinction of a conditioned passive avoidance reflex in mice with genetic knockout of monoamine oxidase A Neurosci. Behav. Physiol. 36 2006 335 339
    • (2006) Neurosci. Behav. Physiol. , vol.36 , pp. 335-339
    • Dubrovina, N.I.1    Popova, N.K.2    Gilinskii, M.A.3    Tomilenko, R.A.4    Seif, I.5
  • 97
    • 0032587055 scopus 로고    scopus 로고
    • 5-HT3 receptor over-expression enhances ethanol sensitivity in mice
    • 3 receptor over-expression enhances ethanol sensitivity in mice Psychopharmacology (Berl.) 144 1999 411 415
    • (1999) Psychopharmacology (Berl.) , vol.144 , pp. 411-415
    • Engel, S.R.1    Allan, A.M.2
  • 98
    • 0031593736 scopus 로고    scopus 로고
    • 5-HT3 receptor over-expression decreases ethanol self administration in transgenic mice
    • 3 receptor over-expression decreases ethanol self administration in transgenic mice Psychopharmacology (Berl.) 140 1998 243 248
    • (1998) Psychopharmacology (Berl.) , vol.140 , pp. 243-248
    • Engel, S.R.1    Lyons, C.R.2    Allan, A.M.3
  • 99
    • 12744273085 scopus 로고    scopus 로고
    • How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing
    • M.T. Englander S.C. Dulawa P. Bhansali C. Schmauss How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing J. Neurosci. 25 2005 648 651
    • (2005) J. Neurosci. , vol.25 , pp. 648-651
    • Englander, M.T.1    Dulawa, S.C.2    Bhansali, P.3    Schmauss, C.4
  • 105
    • 0031802222 scopus 로고    scopus 로고
    • A functional variant of the serotonin transporter gene in families with bipolar affective disorder
    • H. Ewald T. Flint B. Degn O. Mors T.A. Kruse A functional variant of the serotonin transporter gene in families with bipolar affective disorder J. Affect. Disord. 48 1998 135 144
    • (1998) J. Affect. Disord. , vol.48 , pp. 135-144
    • Ewald, H.1    Flint, T.2    Degn, B.3    Mors, O.4    Kruse, T.A.5
  • 107
    • 37348999213 scopus 로고    scopus 로고
    • Increased expression of 5-HT6 receptors in the nucleus accumbens blocks the rewarding but not psychomotor activating properties of cocaine
    • 6 receptors in the nucleus accumbens blocks the rewarding but not psychomotor activating properties of cocaine Biol. Psychiatry 63 2008 207 213
    • (2008) Biol. Psychiatry , vol.63 , pp. 207-213
    • Ferguson, S.M.1    Mitchell, E.S.2    Neumaier, J.F.3
  • 108
    • 0032841176 scopus 로고    scopus 로고
    • An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells
    • C.E. Fiskerstrand E.A. Lovejoy J.P. Quinn An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells FEBS Lett. 458 1999 171 174
    • (1999) FEBS Lett. , vol.458 , pp. 171-174
    • Fiskerstrand, C.E.1    Lovejoy, E.A.2    Quinn, J.P.3
  • 109
    • 0032852842 scopus 로고    scopus 로고
    • Tetrahydropterin-dependent amino acid hydroxylases
    • P.F. Fitzpatrick Tetrahydropterin-dependent amino acid hydroxylases Annu. Rev. Biochem. 68 1999 355 381
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 355-381
    • Fitzpatrick, P.F.1
  • 114
    • 0033588385 scopus 로고    scopus 로고
    • Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoter
    • R.A. Furlong L. Ho J.S. Rubinsztein C. Walsh E.S. Paykel D.C. Rubinsztein Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoter Am. J. Med. Genet. 88 1999 398 406
    • (1999) Am. J. Med. Genet. , vol.88 , pp. 398-406
    • Furlong, R.A.1    Ho, L.2    Rubinsztein, J.S.3    Walsh, C.4    Paykel, E.S.5    Rubinsztein, D.C.6
  • 115
    • 0345258497 scopus 로고    scopus 로고
    • The developmental role of serotonin: news from mouse molecular genetics
    • P. Gaspar O. Cases L. Maroteaux The developmental role of serotonin: news from mouse molecular genetics Nat. Rev. Neurosci. 4 2003 1002 1012
    • (2003) Nat. Rev. Neurosci. , vol.4 , pp. 1002-1012
    • Gaspar, P.1    Cases, O.2    Maroteaux, L.3
  • 116
    • 0035073901 scopus 로고    scopus 로고
    • Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice
    • J.A. Gingrich R. Hen Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice Psychopharmacology (Berl.) 155 2001 1 10
    • (2001) Psychopharmacology (Berl.) , vol.155 , pp. 1-10
    • Gingrich, J.A.1    Hen, R.2
  • 117
    • 32544443899 scopus 로고    scopus 로고
    • Haplotype analysis reveals tryptophan hydroxylase (TPH) 1 gene variants associated with major depression
    • R. Gizatullin G. Zaboli E.G. Jonsson M. Asberg R. Leopardi Haplotype analysis reveals tryptophan hydroxylase (TPH) 1 gene variants associated with major depression Biol. Psychiatry 59 2006 295 300
    • (2006) Biol. Psychiatry , vol.59 , pp. 295-300
    • Gizatullin, R.1    Zaboli, G.2    Jonsson, E.G.3    Asberg, M.4    Leopardi, R.5
  • 118
    • 39649108658 scopus 로고    scopus 로고
    • The tryptophan hydroxylase (TPH) 2 gene unlike TPH-1 exhibits no association with stress-induced depression
    • R. Gizatullin G. Zaboli E.G. Jonsson M. Asberg R. Leopardi The tryptophan hydroxylase (TPH) 2 gene unlike TPH-1 exhibits no association with stress-induced depression J. Affect. Disord. 107 2008 175 179
    • (2008) J. Affect. Disord. , vol.107 , pp. 175-179
    • Gizatullin, R.1    Zaboli, G.2    Jonsson, E.G.3    Asberg, M.4    Leopardi, R.5
  • 119
    • 0042923014 scopus 로고    scopus 로고
    • Midbrain raphe modulation of nonphotic circadian clock resetting and 5-HT release in the mammalian suprachiasmatic nucleus
    • J.D. Glass G.H. Grossman L. Farnbauch L. DiNardo Midbrain raphe modulation of nonphotic circadian clock resetting and 5-HT release in the mammalian suprachiasmatic nucleus J. Neurosci. 23 2003 7451 7460
    • (2003) J. Neurosci. , vol.23 , pp. 7451-7460
    • Glass, J.D.1    Grossman, G.H.2    Farnbauch, L.3    DiNardo, L.4
  • 120
    • 33748365058 scopus 로고    scopus 로고
    • Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression
    • C.E. Glatt E. Carlson T.R. Taylor N. Risch V.I. Reus C.A. Schaefer Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression Neuron 45 2005 11 16 Neuron 48, 704-705; author reply 705-706
    • (2005) Neuron , vol.45 , pp. 11-16
    • Glatt, C.E.1    Carlson, E.2    Taylor, T.R.3    Risch, N.4    Reus, V.I.5    Schaefer, C.A.6
  • 124
    • 0033975193 scopus 로고    scopus 로고
    • Differences in anxiety-related behaviors and in sensitivity to diazepam in inbred and outbred strains of mice
    • G. Griebel C. Belzung G. Perrault D.J. Sanger Differences in anxiety-related behaviors and in sensitivity to diazepam in inbred and outbred strains of mice Psychopharmacology (Berl.) 148 2000 164 170
    • (2000) Psychopharmacology (Berl.) , vol.148 , pp. 164-170
    • Griebel, G.1    Belzung, C.2    Perrault, G.3    Sanger, D.J.4
  • 128
    • 0037171846 scopus 로고    scopus 로고
    • Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims
    • I. Gurevich H. Tamir V. Arango A.J. Dwork J.J. Mann C. Schmauss Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims Neuron 34 2002 349 356
    • (2002) Neuron , vol.34 , pp. 349-356
    • Gurevich, I.1    Tamir, H.2    Arango, V.3    Dwork, A.J.4    Mann, J.J.5    Schmauss, C.6
  • 133
    • 0031706256 scopus 로고    scopus 로고
    • Variability in the serotonin transporter gene and increased risk for major depression with melancholia
    • B. Gutierrez L. Pintor C. Gasto A. Rosa J. Bertranpetit E. Vieta L. Fananas Variability in the serotonin transporter gene and increased risk for major depression with melancholia Hum. Genet. 103 1998 319 322
    • (1998) Hum. Genet. , vol.103 , pp. 319-322
    • Gutierrez, B.1    Pintor, L.2    Gasto, C.3    Rosa, A.4    Bertranpetit, J.5    Vieta, E.6    Fananas, L.7
  • 135
    • 11144234338 scopus 로고    scopus 로고
    • Association analysis between a functional polymorphism in the monoamine oxidase A gene promoter and severe mood disorders; Psychiatr
    • B. Gutierrez B. Arias C. Gasto R. Catalan S. Papiol L. Pintor L. Fananas Association analysis between a functional polymorphism in the monoamine oxidase A gene promoter and severe mood disorders; Psychiatr Genet. 14 2004 203 208
    • (2004) Genet. , vol.14 , pp. 203-208
    • Gutierrez, B.1    Arias, B.2    Gasto, C.3    Catalan, R.4    Papiol, S.5    Pintor, L.6    Fananas, L.7
  • 138
    • 33845760846 scopus 로고    scopus 로고
    • Association between the tryptophan hydroxylase-1 gene A218C polymorphism and citalopram antidepressant response in a Korean population
    • B.J. Ham B.C. Lee J.W. Paik R.H. Kang M.J. Choi I.G. Choi M.S. Lee Association between the tryptophan hydroxylase-1 gene A218C polymorphism and citalopram antidepressant response in a Korean population Prog. Neuropsychopharmacol. Biol. Psychiatry 31 2007 104 107
    • (2007) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.31 , pp. 104-107
    • Ham, B.J.1    Lee, B.C.2    Paik, J.W.3    Kang, R.H.4    Choi, M.J.5    Choi, I.G.6    Lee, M.S.7
  • 139
    • 0032446985 scopus 로고    scopus 로고
    • Gs protein-coupled serotonin receptors: receptor isoforms and functional differences
    • M.W. Hamblin C.R. Guthrie R. Kohen D.E. Heidmann Gs protein-coupled serotonin receptors: receptor isoforms and functional differences Ann. NY Acad. Sci. 861 1998 31 37
    • (1998) Ann. NY Acad. Sci. , vol.861 , pp. 31-37
    • Hamblin, M.W.1    Guthrie, C.R.2    Kohen, R.3    Heidmann, D.E.4
  • 145
    • 0142121567 scopus 로고    scopus 로고
    • Improvements in hippocampal-dependent learning and decremental attention in 5-HT(3) receptor overexpressing mice
    • A.V. Harrell A.M. Allan Improvements in hippocampal-dependent learning and decremental attention in 5-HT(3) receptor overexpressing mice Learn. Mem. 10 2003 410 419
    • (2003) Learn. Mem. , vol.10 , pp. 410-419
    • Harrell, A.V.1    Allan, A.M.2
  • 146
    • 33845665694 scopus 로고    scopus 로고
    • Polymorphisms in the neuronal isoform of tryptophan hydroxylase 2 are associated with bipolar disorder in French Canadian pedigrees
    • M. Harvey B. Gagne M. Labbe N. Barden Polymorphisms in the neuronal isoform of tryptophan hydroxylase 2 are associated with bipolar disorder in French Canadian pedigrees Psychiatr. Genet. 17 2007 17 22
    • (2007) Psychiatr. Genet. , vol.17 , pp. 17-22
    • Harvey, M.1    Gagne, B.2    Labbe, M.3    Barden, N.4
  • 148
    • 33847208084 scopus 로고    scopus 로고
    • The 5-HT7 receptor influences stereotypic behavior in a model of obsessive-compulsive disorder
    • 7 receptor influences stereotypic behavior in a model of obsessive-compulsive disorder Neurosci. Lett. 414 2007 247 251
    • (2007) Neurosci. Lett. , vol.414 , pp. 247-251
    • Hedlund, P.B.1    Sutcliffe, J.G.2
  • 153
    • 0033492916 scopus 로고    scopus 로고
    • The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes; J
    • T. Hendricks N. Francis D. Fyodorov E.S. Deneris The ETS domain factor Pet-1 is an early and precise marker of central serotonin neurons and interacts with a conserved element in serotonergic genes; J Neurosci. 19 1999 10348 10356
    • (1999) Neurosci. , vol.19 , pp. 10348-10356
    • Hendricks, T.1    Francis, N.2    Fyodorov, D.3    Deneris, E.S.4
  • 155
    • 0030058366 scopus 로고    scopus 로고
    • The revised monoamine theory of depression: a modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans
    • G.R. Heninger P.L. Delgado D.S. Charney The revised monoamine theory of depression: a modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans Pharmacopsychiatry 29 1996 2 11
    • (1996) Pharmacopsychiatry , vol.29 , pp. 2-11
    • Heninger, G.R.1    Delgado, P.L.2    Charney, D.S.3
  • 156
    • 14044269534 scopus 로고    scopus 로고
    • Two types of aggression are differentially related to serotonergic activity and the A779C TPH polymorphism
    • J. Hennig M. Reuter P. Netter C. Burk O. Landt Two types of aggression are differentially related to serotonergic activity and the A779C TPH polymorphism Behav. Neurosci. 119 2005 16 25
    • (2005) Behav. Neurosci. , vol.119 , pp. 16-25
    • Hennig, J.1    Reuter, M.2    Netter, P.3    Burk, C.4    Landt, O.5
  • 160
    • 0036897940 scopus 로고    scopus 로고
    • Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter
    • A. Holmes R.J. Yang D.L. Murphy J.N. Crawley Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter Neuropsychopharmacology 27 2002 914 923
    • (2002) Neuropsychopharmacology , vol.27 , pp. 914-923
    • Holmes, A.1    Yang, R.J.2    Murphy, D.L.3    Crawley, J.N.4
  • 161
  • 162
    • 0242600079 scopus 로고    scopus 로고
    • Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior
    • A. Holmes R.J. Yang K.P. Lesch J.N. Crawley D.L. Murphy Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior Neuropsychopharmacology 28 2003 2077 2088
    • (2003) Neuropsychopharmacology , vol.28 , pp. 2077-2088
    • Holmes, A.1    Yang, R.J.2    Lesch, K.P.3    Crawley, J.N.4    Murphy, D.L.5
  • 164
    • 1642578184 scopus 로고    scopus 로고
    • Association study of onset age, attempted suicide, aggressive behavior, and schizophrenia with a serotonin 1B receptor (A-161T) genetic polymorphism
    • C.J. Hong G.M. Pan S.J. Tsai Association study of onset age, attempted suicide, aggressive behavior, and schizophrenia with a serotonin 1B receptor (A-161T) genetic polymorphism Neuropsychobiology 49 2004 1 4
    • (2004) Neuropsychobiology , vol.49 , pp. 1-4
    • Hong, C.J.1    Pan, G.M.2    Tsai, S.J.3
  • 165
    • 0036119338 scopus 로고    scopus 로고
    • Molecular, pharmacological and functional diversity of 5-HT receptors
    • D. Hoyer J.P. Hannon G.R. Martin Molecular, pharmacological and functional diversity of 5-HT receptors Pharmacol. Biochem. Behav. 71 2002 533 554
    • (2002) Pharmacol. Biochem. Behav. , vol.71 , pp. 533-554
    • Hoyer, D.1    Hannon, J.P.2    Martin, G.R.3
  • 166
    • 0032973456 scopus 로고    scopus 로고
    • Relationship of psychopathology to the human serotonin1B genotype and receptor binding kinetics in postmortem brain tissue
    • Y.Y. Huang R. Grailhe V. Arango R. Hen J.J. Mann Relationship of psychopathology to the human serotonin1B genotype and receptor binding kinetics in postmortem brain tissue Neuropsychopharmacology 21 1999 238 246
    • (1999) Neuropsychopharmacology , vol.21 , pp. 238-246
    • Huang, Y.Y.1    Grailhe, R.2    Arango, V.3    Hen, R.4    Mann, J.J.5
  • 170
    • 33846482062 scopus 로고    scopus 로고
    • Feeling strained? Influence of genetic background on depression-related behavior in mice: a review
    • L.H. Jacobson J.F. Cryan Feeling strained? Influence of genetic background on depression-related behavior in mice: a review Behav. Genet. 37 2007 171 213
    • (2007) Behav. Genet. , vol.37 , pp. 171-213
    • Jacobson, L.H.1    Cryan, J.F.2
  • 173
    • 50249105158 scopus 로고    scopus 로고
    • 3B but which 3B and that's just one of the questions: the heterogeneity of human 5-HT3 receptors
    • A.A. Jensen P.A. Davies H. Brauner-Osborne K. Krzywkowski 3B but which 3B and that's just one of the questions: the heterogeneity of human 5-HT3 receptors Trends Pharmacol. Sci. 29 2008 437 444
    • (2008) Trends Pharmacol. Sci. , vol.29 , pp. 437-444
    • Jensen, A.A.1    Davies, P.A.2    Brauner-Osborne, H.3    Krzywkowski, K.4
  • 175
    • 34249738083 scopus 로고    scopus 로고
    • Tryptophan hydroxylase 1 gene (TPH1) moderates the influence of social support on depressive symptoms in adults
    • M. Jokela K. Raikkonen T. Lehtimaki R. Rontu L. Keltikangas-Jarvinen Tryptophan hydroxylase 1 gene (TPH1) moderates the influence of social support on depressive symptoms in adults J. Affect. Disord. 100 2007 191 197
    • (2007) J. Affect. Disord. , vol.100 , pp. 191-197
    • Jokela, M.1    Raikkonen, K.2    Lehtimaki, T.3    Rontu, R.4    Keltikangas-Jarvinen, L.5
  • 176
    • 19344362051 scopus 로고    scopus 로고
    • Sex differences in the regulation of serotonergic transmission and behavior in 5-HT receptor knockout mice
    • M.D. Jones I. Lucki Sex differences in the regulation of serotonergic transmission and behavior in 5-HT receptor knockout mice Neuropsychopharmacology 30 2005 1039 1047
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1039-1047
    • Jones, M.D.1    Lucki, I.2
  • 177
    • 33748375576 scopus 로고    scopus 로고
    • Are serotonin transporter knockout mice ‘depressed’?: hypoactivity but no anhedonia
    • A.V. Kalueff P.S. Gallagher D.L. Murphy Are serotonin transporter knockout mice ‘depressed’?: hypoactivity but no anhedonia Neuroreport 17 2006 1347 1351
    • (2006) Neuroreport , vol.17 , pp. 1347-1351
    • Kalueff, A.V.1    Gallagher, P.S.2    Murphy, D.L.3
  • 178
    • 34249065202 scopus 로고    scopus 로고
    • Hypolocomotion, anxiety and serotonin syndromelike behavior contribute to the complex phenotype of serotonin transporter knockout mice
    • A.V. Kalueff M.A. Fox P.S. Gallagher D.L. Murphy Hypolocomotion, anxiety and serotonin syndromelike behavior contribute to the complex phenotype of serotonin transporter knockout mice Genes Brain Behav. 6 2007 389 400
    • (2007) Genes Brain Behav. , vol.6 , pp. 389-400
    • Kalueff, A.V.1    Fox, M.A.2    Gallagher, P.S.3    Murphy, D.L.4
  • 179
    • 34548516132 scopus 로고    scopus 로고
    • Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice
    • A.V. Kalueff C.L. Jensen D.L. Murphy Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice Brain Res. 1169 2007 87 97
    • (2007) Brain Res. , vol.1169 , pp. 87-97
    • Kalueff, A.V.1    Jensen, C.L.2    Murphy, D.L.3
  • 180
    • 0033135862 scopus 로고    scopus 로고
    • Family-based association studies support a sexually dimorphic effect of COMT and MAOA on genetic susceptibility to obsessive-compulsive disorder
    • M. Karayiorgou C. Sobin M.L. Blundell B.L. Galke L. Malinova P. Goldberg J. Ott J.A. Gogos Family-based association studies support a sexually dimorphic effect of COMT and MAOA on genetic susceptibility to obsessive-compulsive disorder Biol. Psychiatry 45 1999 1178 1189
    • (1999) Biol. Psychiatry , vol.45 , pp. 1178-1189
    • Karayiorgou, M.1    Sobin, C.2    Blundell, M.L.3    Galke, B.L.4    Malinova, L.5    Goldberg, P.6    Ott, J.7    Gogos, J.A.8
  • 181
    • 33747396949 scopus 로고    scopus 로고
    • Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients
    • M. Kato T. Fukuda M. Wakeno K. Fukuda G. Okugawa Y. Ikenaga M. Yamashita Y. Takekita K. Nobuhara J. Azuma T. Kinoshita Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients Neuropsychobiology 53 2006 186 195
    • (2006) Neuropsychobiology , vol.53 , pp. 186-195
    • Kato, M.1    Fukuda, T.2    Wakeno, M.3    Fukuda, K.4    Okugawa, G.5    Ikenaga, Y.6    Yamashita, M.7    Takekita, Y.8    Nobuhara, K.9    Azuma, J.10    Kinoshita, T.11
  • 183
    • 0028843111 scopus 로고
    • Possible association between monoamine oxidase A gene and bipolar affective disorder
    • Y. Kawada M. Hattori X.Y. Dai S. Nanko Possible association between monoamine oxidase A gene and bipolar affective disorder Am. J. Hum. Genet. 56 1995 335 336
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 335-336
    • Kawada, Y.1    Hattori, M.2    Dai, X.Y.3    Nanko, S.4
  • 184
    • 0037423026 scopus 로고    scopus 로고
    • Targeted gene deletion of the 5-HT3A receptor subunit produces an anxiolytic phenotype in mice
    • 3A receptor subunit produces an anxiolytic phenotype in mice Eur. J. Pharmacol. 461 2003 19 25
    • (2003) Eur. J. Pharmacol. , vol.461 , pp. 19-25
    • Kelley, S.P.1    Bratt, A.M.2    Hodge, C.W.3
  • 185
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication
    • K.S. Kendler J.W. Kuhn J. Vittum C.A. Prescott B. Riley The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication Arch. Gen. Psychiatry 62 2005 529 535
    • (2005) Arch. Gen. Psychiatry , vol.62 , pp. 529-535
    • Kendler, K.S.1    Kuhn, J.W.2    Vittum, J.3    Prescott, C.A.4    Riley, B.5
  • 186
    • 0032403133 scopus 로고    scopus 로고
    • Anxiolytic-like actions of BW 723C86 in the rat Vogel conflict test are 5-HT2B receptor mediated
    • 2B receptor mediated Neuropharmacology 37 1998 1603 1610
    • (1998) Neuropharmacology , vol.37 , pp. 1603-1610
    • Kennett, G.A.1    Trail, B.2    Bright, F.3
  • 187
    • 36749103154 scopus 로고    scopus 로고
    • Metaanalyses suggest association between COMT, but not HTR1B, alleles, and suicidal behavior
    • B.M. Kia-Keating S.J. Glatt M.T. Tsuang Metaanalyses suggest association between COMT, but not HTR1B, alleles, and suicidal behavior Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B 2007 1048 1053
    • (2007) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.144B , pp. 1048-1053
    • Kia-Keating, B.M.1    Glatt, S.J.2    Tsuang, M.T.3
  • 189
    • 33751019487 scopus 로고    scopus 로고
    • Tryptophan hydroxylase and serotonin transporter gene polymorphism does not affect the diagnosis, clinical features and treatment outcome of panic disorder in the Korean population
    • W. Kim Y.H. Choi K.S. Yoon D.Y. Cho C.U. Pae J.M. Woo Tryptophan hydroxylase and serotonin transporter gene polymorphism does not affect the diagnosis, clinical features and treatment outcome of panic disorder in the Korean population Prog. Neuropsychopharmacol. Biol. Psychiatry 30 2006 1413 1418
    • (2006) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.30 , pp. 1413-1418
    • Kim, W.1    Choi, Y.H.2    Yoon, K.S.3    Cho, D.Y.4    Pae, C.U.5    Woo, J.M.6
  • 192
    • 28044463376 scopus 로고    scopus 로고
    • Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains
    • A.V. Kulikov D.V. Osipova V.S. Naumenko N.K. Popova Association between Tph2 gene polymorphism, brain tryptophan hydroxylase activity and aggressiveness in mouse strains Genes Brain Behav. 4 2005 482 485
    • (2005) Genes Brain Behav. , vol.4 , pp. 482-485
    • Kulikov, A.V.1    Osipova, D.V.2    Naumenko, V.S.3    Popova, N.K.4
  • 193
    • 0031423428 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder
    • H. Kunugi M. Hattori T. Kato M. Tatsumi T. Sakai T. Sasaki T. Hirose S. Nanko Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder Mol. Psychiatry 2 1997 457 462
    • (1997) Mol. Psychiatry , vol.2 , pp. 457-462
    • Kunugi, H.1    Hattori, M.2    Kato, T.3    Tatsumi, M.4    Sakai, T.5    Sasaki, T.6    Hirose, T.7    Nanko, S.8
  • 194
    • 0032895446 scopus 로고    scopus 로고
    • No evidence for an association of polymorphisms of the tryptophan hydroxylase gene with affective disorders or attempted suicide among Japanese patients
    • H. Kunugi S. Ishida T. Kato T. Sakai M. Tatsumi T. Hirose S. Nanko No evidence for an association of polymorphisms of the tryptophan hydroxylase gene with affective disorders or attempted suicide among Japanese patients Am. J. Psychiatry 156 1999 774 776
    • (1999) Am. J. Psychiatry , vol.156 , pp. 774-776
    • Kunugi, H.1    Ishida, S.2    Kato, T.3    Sakai, T.4    Tatsumi, M.5    Hirose, T.6    Nanko, S.7
  • 197
    • 26444511725 scopus 로고    scopus 로고
    • Polymorphism screening and haplotype analysis of the tryptophan hydroxylase gene (TPH1) and association with bipolar affective disorder in Taiwan
    • T.J. Lai C.Y. Wu H.W. Tsai Y.M. Lin H.S. Sun Polymorphism screening and haplotype analysis of the tryptophan hydroxylase gene (TPH1) and association with bipolar affective disorder in Taiwan BMC Med. Genet. 6 2005 14
    • (2005) BMC Med. Genet. , vol.6 , pp. 14
    • Lai, T.J.1    Wu, C.Y.2    Tsai, H.W.3    Lin, Y.M.4    Sun, H.S.5
  • 198
    • 0037043028 scopus 로고    scopus 로고
    • Meta-analysis of the association between tryptophan hydroxylase and suicidal behavior
    • A. Lalovic G. Turecki Meta-analysis of the association between tryptophan hydroxylase and suicidal behavior Am. J. Med. Genet. 114 2002 533 540
    • (2002) Am. J. Med. Genet. , vol.114 , pp. 533-540
    • Lalovic, A.1    Turecki, G.2
  • 199
  • 200
    • 2342487977 scopus 로고    scopus 로고
    • No association of a functional polymorphism in the serotonin transporter gene promoter and anxiety-related personality traits
    • U.E. Lang M. Bajbouj C. Wernicke H. Rommelspacher H. Danker-Hopfe J. Gallinat No association of a functional polymorphism in the serotonin transporter gene promoter and anxiety-related personality traits Neuropsychobiology 49 2004 182 184
    • (2004) Neuropsychobiology , vol.49 , pp. 182-184
    • Lang, U.E.1    Bajbouj, M.2    Wernicke, C.3    Rommelspacher, H.4    Danker-Hopfe, H.5    Gallinat, J.6
  • 201
    • 12944312689 scopus 로고    scopus 로고
    • Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders
    • J.A. Lasky-Su S.V. Faraone S.J. Glatt M.T. Tsuang Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders Am. J. Med. Genet. B Neuropsychiatr. Genet. 133B 2005 110 115
    • (2005) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.133B , pp. 110-115
    • Lasky-Su, J.A.1    Faraone, S.V.2    Glatt, S.J.3    Tsuang, M.T.4
  • 202
  • 204
    • 10644242682 scopus 로고    scopus 로고
    • Association of the C(-1019)G 5-HT1A functional promoter polymorphism with antidepressant response
    • S. Lemonde L. Du D. Bakish P. Hrdina P.R. Albert Association of the C(-1019)G 5-HT1A functional promoter polymorphism with antidepressant response Intl. J. Neuropsychopharmacol. 7 2004 501 506
    • (2004) Intl. J. Neuropsychopharmacol. , vol.7 , pp. 501-506
    • Lemonde, S.1    Du, L.2    Bakish, D.3    Hrdina, P.4    Albert, P.R.5
  • 207
    • 33646425359 scopus 로고    scopus 로고
    • Association of attention-deficit/hyperactivity disorder with serotonin 4 receptor gene polymorphisms in Han Chinese subjects
    • J. Li Y. Wang R. Zhou B. Wang H. Zhang L. Yang S.V. Faraone Association of attention-deficit/hyperactivity disorder with serotonin 4 receptor gene polymorphisms in Han Chinese subjects Neurosci Lett 401 2006 6 9
    • (2006) Neurosci Lett , vol.401 , pp. 6-9
    • Li, J.1    Wang, Y.2    Zhou, R.3    Wang, B.4    Zhang, H.5    Yang, L.6    Faraone, S.V.7
  • 208
    • 0032706095 scopus 로고    scopus 로고
    • Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice
    • Q. Li C. Wichems A. Heils L.D. Van De Kar K.P. Lesch D.L. Murphy Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice J. Pharmacol. Exp. Ther. 291 1999 999 1007
    • (1999) J. Pharmacol. Exp. Ther. , vol.291 , pp. 999-1007
    • Li, Q.1    Wichems, C.2    Heils, A.3    Van De Kar, L.D.4    Lesch, K.P.5    Murphy, D.L.6
  • 209
    • 34548437582 scopus 로고    scopus 로고
    • Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese
    • Y.M. Lin S.C. Chao T.M. Chen T.J. Lai J.S. Chen H.S. Sun Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese Arch. Gen. Psychiatry 64 2007 1015 1024
    • (2007) Arch. Gen. Psychiatry , vol.64 , pp. 1015-1024
    • Lin, Y.M.1    Chao, S.C.2    Chen, T.M.3    Lai, T.J.4    Chen, J.S.5    Sun, H.S.6
  • 211
    • 33846216741 scopus 로고    scopus 로고
    • Nested association between genetic variation in tryptophan hydroxylase II, bipolar affective disorder, and suicide attempts
    • V.A. Lopez S. Detera-Wadleigh I. Cardona L. Kassem F.J. McMahon Nested association between genetic variation in tryptophan hydroxylase II, bipolar affective disorder, and suicide attempts Biol. Psychiatry 61 2007 181 186
    • (2007) Biol. Psychiatry , vol.61 , pp. 181-186
    • Lopez, V.A.1    Detera-Wadleigh, S.2    Cardona, I.3    Kassem, L.4    McMahon, F.J.5
  • 212
    • 0037270399 scopus 로고    scopus 로고
    • The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit
    • E.A. Lovejoy A.C. Scott C.E. Fiskerstrand V.J. Bubb J.P. Quinn The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit Eur. J. Neurosci. 17 2003 417 420
    • (2003) Eur. J. Neurosci. , vol.17 , pp. 417-420
    • Lovejoy, E.A.1    Scott, A.C.2    Fiskerstrand, C.E.3    Bubb, V.J.4    Quinn, J.P.5
  • 216
    • 0032145210 scopus 로고    scopus 로고
    • The spectrum of behaviors influenced by serotonin
    • I. Lucki The spectrum of behaviors influenced by serotonin Biol. Psychiatry 44 1998 151 162
    • (1998) Biol. Psychiatry , vol.44 , pp. 151-162
    • Lucki, I.1
  • 217
    • 2142822258 scopus 로고    scopus 로고
    • Distinguishing roles for norepinephrine and serotonin in the behavioral effects of antidepressant drugs
    • I. Lucki O.F. O'Leary Distinguishing roles for norepinephrine and serotonin in the behavioral effects of antidepressant drugs J. Clin. Psychiatry 65 Suppl 4 2004 11 24
    • (2004) J. Clin. Psychiatry , vol.65 , Issue.Suppl 4 , pp. 11-24
    • Lucki, I.1    O'Leary, O.F.2
  • 218
    • 0024549545 scopus 로고
    • Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl) piperazine on locomotor activity
    • I. Lucki H.R. Ward A. Frazer Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl) piperazine on locomotor activity J. Pharmacol. Exp. Ther. 249 1989 155 164
    • (1989) J. Pharmacol. Exp. Ther. , vol.249 , pp. 155-164
    • Lucki, I.1    Ward, H.R.2    Frazer, A.3
  • 219
    • 0033593033 scopus 로고    scopus 로고
    • A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo
    • A. MacKenzie J. Quinn A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo Proc. Natl. Acad. Sci. USA 96 1999 15251 15255
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 15251-15255
    • MacKenzie, A.1    Quinn, J.2
  • 220
    • 33750313988 scopus 로고    scopus 로고
    • Serotonin transporter, tryptophan hydroxylase, and monoamine oxidase A gene polymorphisms in premenstrual dysphoric disorder
    • J.L. Magnay K.M. Ismail G. Chapman L. Cioni P.W. Jones S. O'Brien Serotonin transporter, tryptophan hydroxylase, and monoamine oxidase A gene polymorphisms in premenstrual dysphoric disorder Am. J. Obstet. Gynecol. 195 2006 1254 1259
    • (2006) Am. J. Obstet. Gynecol. , vol.195 , pp. 1254-1259
    • Magnay, J.L.1    Ismail, K.M.2    Chapman, G.3    Cioni, L.4    Jones, P.W.5    O'Brien, S.6
  • 223
    • 0033565617 scopus 로고    scopus 로고
    • 5-HT1B receptor knockout mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze
    • 1B receptor knockout mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze J. Neurosci. 19 1999 6157 6168
    • (1999) J. Neurosci. , vol.19 , pp. 6157-6168
    • Malleret, G.1    Hen, R.2    Guillou, J.L.3    Segu, L.4    Buhot, M.C.5
  • 225
    • 0033937080 scopus 로고    scopus 로고
    • A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity
    • S.B. Manuck J.D. Flory R.E. Ferrell J.J. Mann M.F. Muldoon A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity Psychiatry Res. 95 2000 9 23
    • (2000) Psychiatry Res. , vol.95 , pp. 9-23
    • Manuck, S.B.1    Flory, J.D.2    Ferrell, R.E.3    Mann, J.J.4    Muldoon, M.F.5
  • 231
    • 0027339423 scopus 로고
    • Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization
    • H. Matthes U. Boschert N. Amlaiky R. Grailhe J.L. Plassat F. Muscatelli M.G. Mattei R. Hen Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization Mol. Pharmacol. 43 1993 313 319
    • (1993) Mol. Pharmacol. , vol.43 , pp. 313-319
    • Matthes, H.1    Boschert, U.2    Amlaiky, N.3    Grailhe, R.4    Plassat, J.L.5    Muscatelli, F.6    Mattei, M.G.7    Hen, R.8
  • 232
    • 0034887953 scopus 로고    scopus 로고
    • Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice
    • A.J. Mayorga A. Dalvi M.E. Page S. Zimov-Levinson R. Hen I. Lucki Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice J. Pharmacol. Exp. Ther. 298 2001 1101 1107
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 1101-1107
    • Mayorga, A.J.1    Dalvi, A.2    Page, M.E.3    Zimov-Levinson, S.4    Hen, R.5    Lucki, I.6
  • 234
  • 236
    • 25144499477 scopus 로고    scopus 로고
    • Allelic association analysis of the functional insertion/deletion polymorphism in the promoter region of the serotonin transporter gene in bipolar affective disorder
    • I. Meira-Lima L. Michelon Q. Cordeiro H.J. Cho H. Vallada Allelic association analysis of the functional insertion/deletion polymorphism in the promoter region of the serotonin transporter gene in bipolar affective disorder J. Mol. Neurosci. 27 2005 219 224
    • (2005) J. Mol. Neurosci. , vol.27 , pp. 219-224
    • Meira-Lima, I.1    Michelon, L.2    Cordeiro, Q.3    Cho, H.J.4    Vallada, H.5
  • 243
    • 0038389075 scopus 로고    scopus 로고
    • 5-HT 1A/1B receptor-mediated effects of the selective serotonin reuptake inhibitor, citalopram, on sleep: studies in 5-HT 1A and 5-HT 1B knockout mice
    • C. Monaca B. Boutrel R. Hen M. Hamon J. Adrien 5-HT 1A/1B receptor-mediated effects of the selective serotonin reuptake inhibitor, citalopram, on sleep: studies in 5-HT 1A and 5-HT 1B knockout mice Neuropsychopharmacology 28 2003 850 856
    • (2003) Neuropsychopharmacology , vol.28 , pp. 850-856
    • Monaca, C.1    Boutrel, B.2    Hen, R.3    Hamon, M.4    Adrien, J.5
  • 244
    • 34250209118 scopus 로고    scopus 로고
    • Association between A218C polymorphism of the tryptophan-hydroxylase-1 gene, harm avoidance and binge eating behavior in bulimia nervosa
    • P. Monteleone A. Tortorella V. Martiadis I. Serino C. Di Filippo M. Maj Association between A218C polymorphism of the tryptophan-hydroxylase-1 gene, harm avoidance and binge eating behavior in bulimia nervosa Neurosci. Lett. 421 2007 42 46
    • (2007) Neurosci. Lett. , vol.421 , pp. 42-46
    • Monteleone, P.1    Tortorella, A.2    Martiadis, V.3    Serino, I.4    Di Filippo, C.5    Maj, M.6
  • 249
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: insights into human neurobiology
    • D.L. Murphy K.P. Lesch Targeting the murine serotonin transporter: insights into human neurobiology Nat. Rev. Neurosci. 9 2008 85 96
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.P.2
  • 262
    • 0037315191 scopus 로고    scopus 로고
    • Hyperactivity and reduced energy cost of physical activity in serotonin 5-HT(2C) receptor mutant mice
    • K. Nonogaki L. Abdallah E.H. Goulding S.J. Bonasera L.H. Tecott Hyperactivity and reduced energy cost of physical activity in serotonin 5-HT(2C) receptor mutant mice Diabetes 52 2003 315 320
    • (2003) Diabetes , vol.52 , pp. 315-320
    • Nonogaki, K.1    Abdallah, L.2    Goulding, E.H.3    Bonasera, S.J.4    Tecott, L.H.5
  • 266
    • 1842845081 scopus 로고    scopus 로고
    • Polymorphisms of the tryptophan hydroxylase gene and serotonin 1A receptor gene in suicide victims among Japanese
    • M. Ohtani S. Shindo N. Yoshioka Polymorphisms of the tryptophan hydroxylase gene and serotonin 1A receptor gene in suicide victims among Japanese Tohoku J. Exp. Med. 202 2004 123 133
    • (2004) Tohoku J. Exp. Med. , vol.202 , pp. 123-133
    • Ohtani, M.1    Shindo, S.2    Yoshioka, N.3
  • 269
    • 34247872922 scopus 로고    scopus 로고
    • Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test
    • O.F. O'Leary A.J. Bechtholt J.J. Crowley T.E. Hill M.E. Page I. Lucki Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test Psychopharmacology (Berl.) 192 2007 357 371
    • (2007) Psychopharmacology (Berl.) , vol.192 , pp. 357-371
    • O'Leary, O.F.1    Bechtholt, A.J.2    Crowley, J.J.3    Hill, T.E.4    Page, M.E.5    Lucki, I.6
  • 276
    • 0030866457 scopus 로고    scopus 로고
    • Genetic association between monoamine oxidase and manic-depressive illness: comparison of relative risk and haplotype relative risk data
    • A. Parsian R.D. Todd Genetic association between monoamine oxidase and manic-depressive illness: comparison of relative risk and haplotype relative risk data Am. J. Med. Genet. 74 1997 475 479
    • (1997) Am. J. Med. Genet. , vol.74 , pp. 475-479
    • Parsian, A.1    Todd, R.D.2
  • 279
    • 27844539882 scopus 로고    scopus 로고
    • Antipanic efficacy of paroxetine and polymorphism within the promoter of the serotonin transporter gene
    • G. Perna E. Favaron D. Di Bella R. Bussi L. Bellodi Antipanic efficacy of paroxetine and polymorphism within the promoter of the serotonin transporter gene Neuropsychopharmacology 30 2005 2230 2235
    • (2005) Neuropsychopharmacology , vol.30 , pp. 2230-2235
    • Perna, G.1    Favaron, E.2    Di Bella, D.3    Bussi, R.4    Bellodi, L.5
  • 282
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: a convergence of mechanisms
    • C. Pittenger R.S. Duman Stress, depression, and neuroplasticity: a convergence of mechanisms Neuropsychopharmacology 33 2008 88 109
    • (2008) Neuropsychopharmacology , vol.33 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 296
    • 0037097014 scopus 로고    scopus 로고
    • Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
    • 2C receptor gene polymorphism Lancet 359 2002 2086 2087
    • (2002) Lancet , vol.359 , pp. 2086-2087
    • Reynolds, G.P.1    Zhang, Z.J.2    Zhang, X.B.3
  • 297
    • 13244262700 scopus 로고    scopus 로고
    • Pharmacogenetics of treatment in first-episode schizophrenia: D3 and 5-HT2C receptor polymorphisms separately associate with positive and negative symptom response
    • 2C receptor polymorphisms separately associate with positive and negative symptom response Eur. Neuropsychopharmacol. 15 2005 143 151
    • (2005) Eur. Neuropsychopharmacol. , vol.15 , pp. 143-151
    • Reynolds, G.P.1    Yao, Z.2    Zhang, X.3    Sun, J.4    Zhang, Z.5
  • 303
    • 0036364912 scopus 로고    scopus 로고
    • Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder
    • A. Rotondo C. Mazzanti L. Dell'Osso P. Rucci P. Sullivan S. Bouanani C. Gonnelli D. Goldman G.B. Cassano Catechol o-methyltransferase, serotonin transporter, and tryptophan hydroxylase gene polymorphisms in bipolar disorder patients with and without comorbid panic disorder Am. J. Psychiatry 159 2002 23 29
    • (2002) Am. J. Psychiatry , vol.159 , pp. 23-29
    • Rotondo, A.1    Mazzanti, C.2    Dell'Osso, L.3    Rucci, P.4    Sullivan, P.5    Bouanani, S.6    Gonnelli, C.7    Goldman, D.8    Cassano, G.B.9
  • 305
    • 0142042980 scopus 로고    scopus 로고
    • Genetic variations in tryptophan hydroxylase in suicidal behavior: analysis and meta-analysis
    • D. Rujescu I. Giegling T. Sato A.M. Hartmann H.J. Moller Genetic variations in tryptophan hydroxylase in suicidal behavior: analysis and meta-analysis Biol. Psychiatry 54 2003 465 473
    • (2003) Biol. Psychiatry , vol.54 , pp. 465-473
    • Rujescu, D.1    Giegling, I.2    Sato, T.3    Hartmann, A.M.4    Moller, H.J.5
  • 311
    • 0034667334 scopus 로고    scopus 로고
    • The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death
    • R.M. Sapolsky The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death Biol. Psychiatry 48 2000 755 765
    • (2000) Biol. Psychiatry , vol.48 , pp. 755-765
    • Sapolsky, R.M.1
  • 312
    • 0034687815 scopus 로고    scopus 로고
    • Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors
    • Z. Sarnyai E.L. Sibille C. Pavlides R.J. Fenster B.S. McEwen M. Toth Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors Proc. Natl. Acad. Sci. USA 97 2000 14731 14736
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14731-14736
    • Sarnyai, Z.1    Sibille, E.L.2    Pavlides, C.3    Fenster, R.J.4    McEwen, B.S.5    Toth, M.6
  • 316
    • 1542314848 scopus 로고    scopus 로고
    • A meta-analysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety
    • J.A. Schinka R.M. Busch N. Robichaux-Keene A meta-analysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety Mol. Psychiatry 9 2004 197 202
    • (2004) Mol. Psychiatry , vol.9 , pp. 197-202
    • Schinka, J.A.1    Busch, R.M.2    Robichaux-Keene, N.3
  • 317
    • 0028912433 scopus 로고
    • Vesicular neurotransmitter transporters: from bacteria to humans
    • S. Schuldiner A. Shirvan M. Linial Vesicular neurotransmitter transporters: from bacteria to humans Physiol. Rev. 75 1995 369 392
    • (1995) Physiol. Rev. , vol.75 , pp. 369-392
    • Schuldiner, S.1    Shirvan, A.2    Linial, M.3
  • 319
    • 42349093469 scopus 로고    scopus 로고
    • Novel monoamine oxidase A knock out mice with human-like spontaneous mutation
    • A.L. Scott M. Bortolato K. Chen J.C. Shih Novel monoamine oxidase A knock out mice with human-like spontaneous mutation Neuroreport 19 2008 739 743
    • (2008) Neuroreport , vol.19 , pp. 739-743
    • Scott, A.L.1    Bortolato, M.2    Chen, K.3    Shih, J.C.4
  • 320
    • 0346250851 scopus 로고    scopus 로고
    • 5-ht5B receptor mRNA in the raphe nuclei: coexpression with serotonin transporter
    • J. Serrats A. Raurich M.T. Vilaro G. Mengod R. Cortes 5-ht5B receptor mRNA in the raphe nuclei: coexpression with serotonin transporter Synapse (NY) 51 2004 102 111
    • (2004) Synapse (NY) , vol.51 , pp. 102-111
    • Serrats, J.1    Raurich, A.2    Vilaro, M.T.3    Mengod, G.4    Cortes, R.5
  • 321
    • 0032781402 scopus 로고    scopus 로고
    • Tryptophan hydroxylase gene and response to lithium prophylaxis in mood disorders
    • A. Serretti R. Lilli C. Lorenzi M. Gasperini E. Smeraldi Tryptophan hydroxylase gene and response to lithium prophylaxis in mood disorders J. Psychiatr. Res. 33 1999 371 377
    • (1999) J. Psychiatr. Res. , vol.33 , pp. 371-377
    • Serretti, A.1    Lilli, R.2    Lorenzi, C.3    Gasperini, M.4    Smeraldi, E.5
  • 322
    • 0034885170 scopus 로고    scopus 로고
    • Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity
    • A. Serretti R. Zanardi D. Rossini C. Cusin R. Lilli E. Smeraldi Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity Mol. Psychiatry 6 2001 586 592
    • (2001) Mol. Psychiatry , vol.6 , pp. 586-592
    • Serretti, A.1    Zanardi, R.2    Rossini, D.3    Cusin, C.4    Lilli, R.5    Smeraldi, E.6
  • 324
    • 10644271666 scopus 로고    scopus 로고
    • The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings
    • A. Serretti P. Artioli C. Lorenzi A. Pirovano V. Tubazio R. Zanardi The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings Intl. J. Neuropsychopharmacol. 7 2004 453 460
    • (2004) Intl. J. Neuropsychopharmacol. , vol.7 , pp. 453-460
    • Serretti, A.1    Artioli, P.2    Lorenzi, C.3    Pirovano, A.4    Tubazio, V.5    Zanardi, R.6
  • 328
    • 0034655423 scopus 로고    scopus 로고
    • Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety
    • E. Sibille C. Pavlides D. Benke M. Toth Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety J. Neurosci. 20 2000 2758 2765
    • (2000) J. Neurosci. , vol.20 , pp. 2758-2765
    • Sibille, E.1    Pavlides, C.2    Benke, D.3    Toth, M.4
  • 330
    • 7144227374 scopus 로고    scopus 로고
    • Serotonergic control of the organization of feeding and satiety
    • K.J. Simansky Serotonergic control of the organization of feeding and satiety Behav. Brain Res. 73 1996 37 42
    • (1996) Behav. Brain Res. , vol.73 , pp. 37-42
    • Simansky, K.J.1
  • 331
    • 0031736757 scopus 로고    scopus 로고
    • Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine
    • E. Smeraldi R. Zanardi F. Benedetti D. Di Bella J. Perez M. Catalano Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine Mol. Psychiatry 3 1998 508 511
    • (1998) Mol. Psychiatry , vol.3 , pp. 508-511
    • Smeraldi, E.1    Zanardi, R.2    Benedetti, F.3    Di Bella, D.4    Perez, J.5    Catalano, M.6
  • 336
    • 16244402653 scopus 로고    scopus 로고
    • Variability of the tryptophan hydroxylase gene: study in victims of violent suicide
    • J. Stefulj M. Kubat M. Balija J. Skavic B. Jernej Variability of the tryptophan hydroxylase gene: study in victims of violent suicide Psychiatry Res. 134 2005 67 73
    • (2005) Psychiatry Res. , vol.134 , pp. 67-73
    • Stefulj, J.1    Kubat, M.2    Balija, M.3    Skavic, J.4    Jernej, B.5
  • 337
    • 0346731044 scopus 로고    scopus 로고
    • Allelic variation in 5-HT1A receptor expression is associated with anxiety- and depression-related personality traits
    • A. Strobel L. Gutknecht C. Rothe A. Reif R. Mossner Y. Zeng B. Brocke K.P. Lesch Allelic variation in 5-HT1A receptor expression is associated with anxiety- and depression-related personality traits J. Neural. Transm. 110 2003 1445 1453
    • (2003) J. Neural. Transm. , vol.110 , pp. 1445-1453
    • Strobel, A.1    Gutknecht, L.2    Rothe, C.3    Reif, A.4    Mossner, R.5    Zeng, Y.6    Brocke, B.7    Lesch, K.P.8
  • 339
    • 4344637548 scopus 로고    scopus 로고
    • The effects of a 5-hydroxytryptamine 1A receptor gene polymorphism on the clinical response to fluvoxamine in depressed patients
    • Y. Suzuki K. Sawamura T. Someya The effects of a 5-hydroxytryptamine 1A receptor gene polymorphism on the clinical response to fluvoxamine in depressed patients Pharmacogenomics J. 4 2004 283 286
    • (2004) Pharmacogenomics J. , vol.4 , pp. 283-286
    • Suzuki, Y.1    Sawamura, K.2    Someya, T.3
  • 347
    • 17644394540 scopus 로고    scopus 로고
    • Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis
    • 2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis Pharmacogenet. Genomics 15 2005 195 200
    • (2005) Pharmacogenet. Genomics , vol.15 , pp. 195-200
    • Templeman, L.A.1    Reynolds, G.P.2    Arranz, B.3    San, L.4
  • 348
    • 38049004434 scopus 로고    scopus 로고
    • The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioral differences between mouse strains
    • K. Tenner F. Qadri B. Bert J.P. Voigt M. Bader The mTPH2 C1473G single nucleotide polymorphism is not responsible for behavioral differences between mouse strains Neurosci. Lett. 431 2008 21 25
    • (2008) Neurosci. Lett. , vol.431 , pp. 21-25
    • Tenner, K.1    Qadri, F.2    Bert, B.3    Voigt, J.P.4    Bader, M.5
  • 350
    • 33746733586 scopus 로고    scopus 로고
    • 5-ht5A receptors as a therapeutic target
    • D.R. Thomas 5-ht5A receptors as a therapeutic target Pharmacol. Ther. 111 2006 707 714
    • (2006) Pharmacol. Ther. , vol.111 , pp. 707-714
    • Thomas, D.R.1
  • 352
    • 0041972246 scopus 로고    scopus 로고
    • T102C and -1438 G/A polymorphisms of the 5-HT2A receptor gene in Turkish patients with obsessive-compulsive disorder
    • 2A receptor gene in Turkish patients with obsessive-compulsive disorder Eur. Psychiatry 18 2003 249 254
    • (2003) Eur. Psychiatry , vol.18 , pp. 249-254
    • Tot, S.1    Erdal, M.E.2    Yazici, K.3    Yazici, A.E.4    Metin, O.5
  • 353
    • 0033587801 scopus 로고    scopus 로고
    • Association study of serotonin-6 receptor variant (C267T) with schizophrenia and aggressive behavior
    • S.J. Tsai H.J. Chiu Y.C. Wang C.J. Hong Association study of serotonin-6 receptor variant (C267T) with schizophrenia and aggressive behavior Neurosci. Lett. 271 1999 135 137
    • (1999) Neurosci. Lett. , vol.271 , pp. 135-137
    • Tsai, S.J.1    Chiu, H.J.2    Wang, Y.C.3    Hong, C.J.4
  • 354
    • 0037202751 scopus 로고    scopus 로고
    • -759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain
    • S.J. Tsai C.J. Hong Y.W. Yu C.H. Lin -759C/T genetic variation of 5HT(2C) receptor and clozapine-induced weight gain Lancet 360 2002 1790
    • (2002) Lancet , vol.360 , pp. 1790
    • Tsai, S.J.1    Hong, C.J.2    Yu, Y.W.3    Lin, C.H.4
  • 355
    • 4644264502 scopus 로고    scopus 로고
    • Association study of serotonin 1B receptor (A-161T) genetic polymorphism and suicidal behaviors and response to fluoxetine in major depressive disorder
    • S.J. Tsai C.J. Hong Y.W. Yu T.J. Chen Y.C. Wang W.K. Lin Association study of serotonin 1B receptor (A-161T) genetic polymorphism and suicidal behaviors and response to fluoxetine in major depressive disorder Neuropsychobiology 50 2004 235 238
    • (2004) Neuropsychobiology , vol.50 , pp. 235-238
    • Tsai, S.J.1    Hong, C.J.2    Yu, Y.W.3    Chen, T.J.4    Wang, Y.C.5    Lin, W.K.6
  • 356
    • 34347363003 scopus 로고    scopus 로고
    • Suppression of conditioning to ambiguous cues by pharmacogenetic inhibition of the dentate gyrus
    • T. Tsetsenis X.H. Ma L. Lo Iacono S.G. Beck C. Gross Suppression of conditioning to ambiguous cues by pharmacogenetic inhibition of the dentate gyrus Nat. Neurosci. 10 2007 896 902
    • (2007) Nat. Neurosci. , vol.10 , pp. 896-902
    • Tsetsenis, T.1    Ma, X.H.2    Lo Iacono, L.3    Beck, S.G.4    Gross, C.5
  • 357
    • 0034097644 scopus 로고    scopus 로고
    • Negative association between T102C polymorphism at the 5-HT2A receptor gene and bipolar affective disorders in Singaporean Chinese
    • 2A receptor gene and bipolar affective disorders in Singaporean Chinese J. Affect. Disord. 58 2000 211 214
    • (2000) J. Affect. Disord. , vol.58 , pp. 211-214
    • Tut, T.G.1    Wang, J.L.2    Lim, C.C.3
  • 358
    • 33748365058 scopus 로고    scopus 로고
    • Response to Zhang et al (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression
    • A. Van Den Bogaert S. De Zutter L. Heyrman J. Mendlewicz R. Adolfsson C. Van Broeckhoven J. Del-Favero Response to Zhang et al (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression Neuron 45 2005 11 16 Neuron 48, 704; author reply 705-706
    • (2005) Neuron , vol.45 , pp. 11-16
    • Van Den Bogaert, A.1    De Zutter, S.2    Heyrman, L.3    Mendlewicz, J.4    Adolfsson, R.5    Van Broeckhoven, C.6    Del-Favero, J.7
  • 360
    • 4444323618 scopus 로고    scopus 로고
    • Distribution of 5-HT7 receptors in the human brain: a preliminary autoradiographic study using [3H]SB-269970; Neurosci
    • 7 receptors in the human brain: a preliminary autoradiographic study using [3H]SB-269970; Neurosci Lett. 367 2004 313 316
    • (2004) Lett. , vol.367 , pp. 313-316
    • Varnas, K.1    Thomas, D.R.2    Tupala, E.3    Tiihonen, J.4    Hall, H.5
  • 361
    • 0037302791 scopus 로고    scopus 로고
    • Role of selective serotonin reuptake inhibitors in psychiatric disorders: a comprehensive review
    • M. Vaswani F.K. Linda S. Ramesh Role of selective serotonin reuptake inhibitors in psychiatric disorders: a comprehensive review Prog. Neuropsychopharmacol. Biol. Psychiatry 27 2003 85 102
    • (2003) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.27 , pp. 85-102
    • Vaswani, M.1    Linda, F.K.2    Ramesh, S.3
  • 362
    • 0026042832 scopus 로고
    • A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat
    • R.P. Vertes A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat J. Comp. Neurol. 313 1991 643 668
    • (1991) J. Comp. Neurol. , vol.313 , pp. 643-668
    • Vertes, R.P.1
  • 363
    • 0033577751 scopus 로고    scopus 로고
    • Projections of the median raphe nucleus in the rat
    • R.P. Vertes W.J. Fortin A.M. Crane Projections of the median raphe nucleus in the rat J. Comp. Neurol. 407 1999 555 582
    • (1999) J. Comp. Neurol. , vol.407 , pp. 555-582
    • Vertes, R.P.1    Fortin, W.J.2    Crane, A.M.3
  • 365
    • 33846535448 scopus 로고    scopus 로고
    • Effect of MAO A deficiency on different kinds of aggression and social investigation in mice
    • G.B. Vishnivetskaya J.A. Skrinskaya I. Seif N.K. Popova Effect of MAO A deficiency on different kinds of aggression and social investigation in mice Aggress Behav. 33 2007 1 6
    • (2007) Aggress Behav. , vol.33 , pp. 1-6
    • Vishnivetskaya, G.B.1    Skrinskaya, J.A.2    Seif, I.3    Popova, N.K.4
  • 370
    • 0031458923 scopus 로고    scopus 로고
    • Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine
    • Y.M. Wang R.R. Gainetdinov F. Fumagalli F. Xu S.R. Jones C.B. Bock G.W. Miller R.M. Wightman M.G. Caron Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine Neuron 19 1997 1285 1296
    • (1997) Neuron , vol.19 , pp. 1285-1296
    • Wang, Y.M.1    Gainetdinov, R.R.2    Fumagalli, F.3    Xu, F.4    Jones, S.R.5    Bock, C.B.6    Miller, G.W.7    Wightman, R.M.8    Caron, M.G.9
  • 374
    • 34047183030 scopus 로고    scopus 로고
    • Effects of the brain-penetrant and selective 5-HT6 receptor antagonist SB-399885 in animal models of anxiety and depression
    • 6 receptor antagonist SB-399885 in animal models of anxiety and depression Neuropharmacology 52 2007 1274 1283
    • (2007) Neuropharmacology , vol.52 , pp. 1274-1283
    • Wesolowska, A.1    Nikiforuk, A.2
  • 375
    • 39149091707 scopus 로고    scopus 로고
    • The selective 5-HT(6) receptor antagonist SB-399885 enhances anti-immobility action of antidepressants in rats
    • A. Wesolowska A. Nikiforuk The selective 5-HT(6) receptor antagonist SB-399885 enhances anti-immobility action of antidepressants in rats Eur. J. Pharmacol. 582 2008 88 93
    • (2008) Eur. J. Pharmacol. , vol.582 , pp. 88-93
    • Wesolowska, A.1    Nikiforuk, A.2
  • 377
    • 34548383532 scopus 로고    scopus 로고
    • Anxiolytic-like and antidepressant-like effects produced by the selective 5-HT6 receptor antagonist SB-258585 after intrahippocampal administration to rats
    • 6 receptor antagonist SB-258585 after intrahippocampal administration to rats Behav. Pharmacol. 18 2007 439 446
    • (2007) Behav. Pharmacol. , vol.18 , pp. 439-446
    • Wesolowska, A.1    Nikiforuk, A.2    Stachowicz, K.3
  • 380
    • 0037455913 scopus 로고    scopus 로고
    • Serotonin 1B knockout mice exhibit a task-dependent selective learning facilitation
    • M. Wolff M. Savova G. Malleret R. Hen L. Segu M.C. Buhot Serotonin 1B knockout mice exhibit a task-dependent selective learning facilitation Neurosci. Lett. 338 2003 1 4
    • (2003) Neurosci. Lett. , vol.338 , pp. 1-4
    • Wolff, M.1    Savova, M.2    Malleret, G.3    Hen, R.4    Segu, L.5    Buhot, M.C.6
  • 382
    • 15744385450 scopus 로고    scopus 로고
    • Serotonin transporter and tryptophan hydroxylase gene polymorphisms in Chinese patients with generalized anxiety disorder
    • J.S. You S.Y. Hu B. Chen H.G. Zhang Serotonin transporter and tryptophan hydroxylase gene polymorphisms in Chinese patients with generalized anxiety disorder Psychiatr. Genet. 15 2005 7 11
    • (2005) Psychiatr. Genet. , vol.15 , pp. 7-11
    • You, J.S.1    Hu, S.Y.2    Chen, B.3    Zhang, H.G.4
  • 383
    • 33645307953 scopus 로고    scopus 로고
    • The therapeutic potential of monoamine oxidase inhibitors
    • M.B. Youdim D. Edmondson K.F. Tipton The therapeutic potential of monoamine oxidase inhibitors Nat. Rev. Neurosci. 7 2006 295 309
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 295-309
    • Youdim, M.B.1    Edmondson, D.2    Tipton, K.F.3
  • 384
    • 0036931893 scopus 로고    scopus 로고
    • Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders
    • Y.W. Yu S.J. Tsai T.J. Chen C.H. Lin C.J. Hong Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders Mol. Psychiatry 7 2002 1115 1119
    • (2002) Mol. Psychiatry , vol.7 , pp. 1115-1119
    • Yu, Y.W.1    Tsai, S.J.2    Chen, T.J.3    Lin, C.H.4    Hong, C.J.5
  • 385
    • 0034103054 scopus 로고    scopus 로고
    • Identification of polymorphic loci in the promoter region of the serotonin 5-HT2C receptor gene and their association with obesity and type II diabetes
    • 2C receptor gene and their association with obesity and type II diabetes Diabetologia 43 2000 373 376
    • (2000) Diabetologia , vol.43 , pp. 373-376
    • Yuan, X.1    Yamada, K.2    Ishiyama-Shigemoto, S.3    Koyama, W.4    Nonaka, K.5
  • 393
    • 33845423914 scopus 로고    scopus 로고
    • Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity
    • Z.Q. Zhao M. Scott S. Chiechio J.S. Wang K.J. Renner R.W.t. Gereau R.L. Johnson E.S. Deneris Z.F. Chen Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity J. Neurosci. 26 2006 12781 12788
    • (2006) J. Neurosci. , vol.26 , pp. 12781-12788
    • Zhao, Z.Q.1    Scott, M.2    Chiechio, S.3    Wang, J.S.4    Renner, K.J.5    Gereau, R.W.t.6    Johnson, R.L.7    Deneris, E.S.8    Chen, Z.F.9
  • 394
    • 33646379343 scopus 로고    scopus 로고
    • Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice
    • S. Zhao J. Edwards J. Carroll L. Wiedholz R.A. Millstein C. Jaing D.L. Murphy T.H. Lanthorn A. Holmes Insertion mutation at the C-terminus of the serotonin transporter disrupts brain serotonin function and emotion-related behaviors in mice Neuroscience 140 2006 321 334
    • (2006) Neuroscience , vol.140 , pp. 321-334
    • Zhao, S.1    Edwards, J.2    Carroll, J.3    Wiedholz, L.4    Millstein, R.A.5    Jaing, C.6    Murphy, D.L.7    Lanthorn, T.H.8    Holmes, A.9
  • 396
    • 25844486999 scopus 로고    scopus 로고
    • Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations
    • Z. Zhou A. Roy R. Lipsky K. Kuchipudi G. Zhu J. Taubman M.A. Enoch M. Virkkunen D. Goldman Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations Arch. Gen. Psychiatry 62 2005 1109 1118
    • (2005) Arch. Gen. Psychiatry , vol.62 , pp. 1109-1118
    • Zhou, Z.1    Roy, A.2    Lipsky, R.3    Kuchipudi, K.4    Zhu, G.5    Taubman, J.6    Enoch, M.A.7    Virkkunen, M.8    Goldman, D.9
  • 398
    • 33750725388 scopus 로고    scopus 로고
    • Analysis of tryptophan hydroxylase I and II mRNA expression in the human brain: a post-mortem study
    • P. Zill A. Buttner W. Eisenmenger H.J. Moller M. Ackenheil B. Bondy Analysis of tryptophan hydroxylase I and II mRNA expression in the human brain: a post-mortem study J. Psychiatr. Res. 41 2007 168 173
    • (2007) J. Psychiatr. Res. , vol.41 , pp. 168-173
    • Zill, P.1    Buttner, A.2    Eisenmenger, W.3    Moller, H.J.4    Ackenheil, M.5    Bondy, B.6
  • 400
    • 24944471356 scopus 로고    scopus 로고
    • Serotonin receptor 2A gene polymorphism (-1438A/G) and short-term treatment response to citalopram
    • M.J. Choi R.H. Kang B.J. Ham H.Y. Jeong M.S. Lee Serotonin receptor 2A gene polymorphism (-1438A/G) and short-term treatment response to citalopram Neuropsy-chobiology 52 2005 155 162
    • (2005) Neuropsy-chobiology , vol.52 , pp. 155-162
    • Choi, M.J.1    Kang, R.H.2    Ham, B.J.3    Jeong, H.Y.4    Lee, M.S.5
  • 401
    • 0034615109 scopus 로고    scopus 로고
    • Association of polymorphism of serotonin 2A receptor gene with suicidal ideation in major depressive disorder
    • L. Du D. Bakish Y.D. Lapierre A.V. Ravindran P.D. Hrdina Association of polymorphism of serotonin 2A receptor gene with suicidal ideation in major depressive disorder Am. J. Med. Genet. 96 2000 56 60
    • (2000) Am. J. Med. Genet. , vol.96 , pp. 56-60
    • Du, L.1    Bakish, D.2    Lapierre, Y.D.3    Ravindran, A.V.4    Hrdina, P.D.5
  • 402
    • 0035943536 scopus 로고    scopus 로고
    • Association study between novel promoter variants at the 5-HT2C receptor gene and human patients with bipolar affective disorder
    • 2C receptor gene and human patients with bipolar affective disorder Neurosci. Lett. 309 2001 135 137
    • (2001) Neurosci. Lett. , vol.309 , pp. 135-137
    • Gutierrez, B.1    Arias, B.2    Papiol, S.3    Rosa, A.4    Fananas, L.5
  • 404
    • 33750719946 scopus 로고    scopus 로고
    • Effect of SNP at position 40237 in exon 7 of the TPH2 gene on susceptibility to suicide
    • L. Ke Z.Y. Qi Y. Ping C.Y. Ren Effect of SNP at position 40237 in exon 7 of the TPH2 gene on susceptibility to suicide Brain Res. 1122 2006 24 26
    • (2006) Brain Res. , vol.1122 , pp. 24-26
    • Ke, L.1    Qi, Z.Y.2    Ping, Y.3    Ren, C.Y.4
  • 405
    • 0032872035 scopus 로고    scopus 로고
    • Tentative association of the serotonin transporter with schizophrenia and unipolar depression but not with bipolar disorder in Han Chinese
    • W. Liu N. Gu G. Feng S. Li S. Bai J. Zhang T. Shen H. Xue G. Breen D. St Clair L. He Tentative association of the serotonin transporter with schizophrenia and unipolar depression but not with bipolar disorder in Han Chinese Pharmacogenetics 9 1999 491 495
    • (1999) Pharmacogenetics , vol.9 , pp. 491-495
    • Liu, W.1    Gu, N.2    Feng, G.3    Li, S.4    Bai, S.5    Zhang, J.6    Shen, T.7    Xue, H.8    Breen, G.9    St Clair, D.10    He, L.11
  • 407
    • 0029012193 scopus 로고
    • Characterization and distribution of putative 5-ht7 receptors in guinea-pig brain
    • Z.P. To D.W. Bonhaus R.M. Eglen L.B. Jakeman Characterization and distribution of putative 5-ht7 receptors in guinea-pig brain Br. J. Pharmacol. 115 1995 107 116
    • (1995) Br. J. Pharmacol. , vol.115 , pp. 107-116
    • To, Z.P.1    Bonhaus, D.W.2    Eglen, R.M.3    Jakeman, L.B.4
  • 408
    • 27744436005 scopus 로고    scopus 로고
    • Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response
    • Y.W. Yu S.J. Tsai C.J. Hong T.J. Chen M.C. Chen C.W. Yang Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response Neuropsychopharmacology 30 2005 1719 1723
    • (2005) Neuropsychopharmacology , vol.30 , pp. 1719-1723
    • Yu, Y.W.1    Tsai, S.J.2    Hong, C.J.3    Chen, T.J.4    Chen, M.C.5    Yang, C.W.6
  • 409
    • 33748582618 scopus 로고    scopus 로고
    • Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders
    • Y.W. Yu S.J. Tsai Y.J. Liou C.J. Hong T.J. Chen Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders Eur. Neuropsychopharmacol. 16 2006 498 503
    • (2006) Eur. Neuropsychopharmacol. , vol.16 , pp. 498-503
    • Yu, Y.W.1    Tsai, S.J.2    Liou, Y.J.3    Hong, C.J.4    Chen, T.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.