Modeling treatment-resistant depression

Neuropharmacology

Volumn 61, Issue 3, 2011, Pages 408-413

  Samuels, Benjamin Adam ^a,b   Leonardo, Eduardo David ^a   Gadient, Reto ^c   Williams, Amanda ^c   Zhou, Jin ^c   David, Denis J ^d   Gardier, Alain Michel ^d   Wong, Erik H F ^c   Hen, René ^a,b  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c ASTRAZENECA   (United Kingdom)

^d UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Animal models; Chronic stress; Depression; htr1a; Serotonin; SSRI; Treatment resistant

Indexed keywords

CORTICOSTERONE; ESCITALOPRAM; FLUOXETINE; GLUCOCORTICOID; IMIPRAMINE; SEROTONIN 1A RECEPTOR; SEROTONIN UPTAKE INHIBITOR; ANTIDEPRESSANT AGENT; AUTORECEPTOR;

AGGRESSION; ANXIETY; CHRONIC STRESS; CIRCADIAN RHYTHM; DEPRESSION; DISEASE MODEL; DISEASE SEVERITY; DRUG EFFICACY; DRUG RESEARCH; DRUG SAFETY; GENE FREQUENCY; GENETIC ASSOCIATION; MAJOR DEPRESSION; MOLECULAR DYNAMICS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEOMICS; REMISSION; REVIEW; RISK ASSESSMENT; SELF CARE; SEROTONINERGIC SYSTEM; SEXUAL BEHAVIOR; SUGAR INTAKE; ANXIETY DISORDER; BEHAVIOR; BRAIN FUNCTION; CONFERENCE PAPER; CONSTRUCT VALIDITY; DRUG ACTIVITY; LONG TERM CARE; MOBILIZATION; NEGATIVE FEEDBACK; NEUROCHEMISTRY; PREDICTIVE VALIDITY; SOCIAL STRESS; TREATMENT RESPONSE;

ANIMALS; BEHAVIOR, ANIMAL; DEPRESSION; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; DRUG RESISTANCE; HUMANS; RATS; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN UPTAKE INHIBITORS; STRESS, PHYSIOLOGICAL; STRESS, PSYCHOLOGICAL;

EID: 79958094382     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.02.017     Document Type: Review

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