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Volumn 95, Issue 12, 2006, Pages 2673-2683

Kinetic analyses for species differences in P-glycoprotein-mediated drug transport

Author keywords

Drug transport; In vitro models; Kinetics; Multidrug resistance transporters; P glycoprotein; Species differences

Indexed keywords

COMPLEMENTARY DNA; CYCLOSPORIN A; DEXAMETHASONE; DILTIAZEM; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1;

EID: 33846261622     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20686     Document Type: Article
Times cited : (101)

References (25)
  • 1
    • 0026487058 scopus 로고
    • Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone
    • Ueda K, Okamura N, Hirai M, Tanigawara Y, Saeki T, Kioka N, Komano T, Hori R. 1992. Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone. J Biol Chem 267:24248-24252.
    • (1992) J Biol Chem , vol.267 , pp. 24248-24252
    • Ueda, K.1    Okamura, N.2    Hirai, M.3    Tanigawara, Y.4    Saeki, T.5    Kioka, N.6    Komano, T.7    Hori, R.8
  • 2
    • 0028825399 scopus 로고
    • Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
    • Schinkel AH, Wagenaar E, van Deemter L, Mol CA, Borst P. 1995. Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. Clin Invest 96:1698-1705.
    • (1995) Clin Invest , vol.96 , pp. 1698-1705
    • Schinkel, A.H.1    Wagenaar, E.2    van Deemter, L.3    Mol, C.A.4    Borst, P.5
  • 5
    • 0035119989 scopus 로고    scopus 로고
    • In vitro substrate identification studies for P-glycoprotein-mediated transport: Species difference and predictability of in vivo results
    • Yamazaki M, Neway WE, Ohe T, Chen I, Rowe JF, Hochman JH, Chiba M, Lin JH. 2001. In vitro substrate identification studies for P-glycoprotein-mediated transport: Species difference and predictability of in vivo results. J Pharmacol Exp Ther 296: 723-735.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 723-735
    • Yamazaki, M.1    Neway, W.E.2    Ohe, T.3    Chen, I.4    Rowe, J.F.5    Hochman, J.H.6    Chiba, M.7    Lin, J.H.8
  • 6
    • 0028961304 scopus 로고
    • Human (MDR1) and mouse (mdr1, mdr3) P-glycoprotein can be distinguished by their respective drug resistance profiles and sensitivity to modulators
    • Tang-Wai DF, Kajiji S, DiCapua F, de Graaf D, Roninson IB, Gros P. 1995. Human (MDR1) and mouse (mdr1, mdr3) P-glycoprotein can be distinguished by their respective drug resistance profiles and sensitivity to modulators. Biochemistry 34: 32-39.
    • (1995) Biochemistry , vol.34 , pp. 32-39
    • Tang-Wai, D.F.1    Kajiji, S.2    DiCapua, F.3    de Graaf, D.4    Roninson, I.B.5    Gros, P.6
  • 7
    • 0037229942 scopus 로고    scopus 로고
    • Role of P-glycoprotein in pharmacokinetics: Clinical implications
    • Lin JH, Yamazaki M. 2003. Role of P-glycoprotein in pharmacokinetics: Clinical implications. Clin Pharmacokinet 42:59-98.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 59-98
    • Lin, J.H.1    Yamazaki, M.2
  • 8
    • 0035668339 scopus 로고    scopus 로고
    • Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein
    • Adachi Y, Suzuki H, Sugiyama Y. 2001. Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein. Pharm Res 18:1660-1668.
    • (2001) Pharm Res , vol.18 , pp. 1660-1668
    • Adachi, Y.1    Suzuki, H.2    Sugiyama, Y.3
  • 10
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 11
    • 0033636618 scopus 로고    scopus 로고
    • Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: Comparison with the effects on CYP3A4
    • Katoh M, Nakajima M, Yamazaki H, Yokoi T. 2000. Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: Comparison with the effects on CYP3A4. Pharm Res 17:1189-1197.
    • (2000) Pharm Res , vol.17 , pp. 1189-1197
    • Katoh, M.1    Nakajima, M.2    Yamazaki, H.3    Yokoi, T.4
  • 13
    • 0035987203 scopus 로고    scopus 로고
    • Evaluation of drug interactions with P-glycoprotein in drug discovery: In vitro assessment of the potential for drug-drug interactions with P-glycoprotein
    • Hochman JH, Yamazaki M, Ohe T, Lin JH. 2002. Evaluation of drug interactions with P-glycoprotein in drug discovery: In vitro assessment of the potential for drug-drug interactions with P-glycoprotein. Curr Drug Metab 3:257-273.
    • (2002) Curr Drug Metab , vol.3 , pp. 257-273
    • Hochman, J.H.1    Yamazaki, M.2    Ohe, T.3    Lin, J.H.4
  • 14
    • 0041589264 scopus 로고    scopus 로고
    • Utility of Mdr1-gene deficient mice in assessing the impact of P-glycoprotein on pharmacokinetics and pharmacodynamics in drug discovery and development
    • Chen C, Liu X, Smith BJ. 2003. Utility of Mdr1-gene deficient mice in assessing the impact of P-glycoprotein on pharmacokinetics and pharmacodynamics in drug discovery and development. Curr Drug Metab 4:272-291.
    • (2003) Curr Drug Metab , vol.4 , pp. 272-291
    • Chen, C.1    Liu, X.2    Smith, B.J.3
  • 16
    • 0027418815 scopus 로고
    • Human P-glycoprotein transports cyclosporin A and FK506
    • Saeki T, Ueda K, Tanigawara Y, Hori R, Komano T. 1993. Human P-glycoprotein transports cyclosporin A and FK506. J Biol Chem 268:6077-6080.
    • (1993) J Biol Chem , vol.268 , pp. 6077-6080
    • Saeki, T.1    Ueda, K.2    Tanigawara, Y.3    Hori, R.4    Komano, T.5
  • 17
    • 0025141784 scopus 로고
    • Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies
    • Georges E, Bradley G, Gariepy J, Ling V. 1990. Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies. Proc Natl Acad Sci USA 87:152-156.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 152-156
    • Georges, E.1    Bradley, G.2    Gariepy, J.3    Ling, V.4
  • 18
    • 0042125510 scopus 로고    scopus 로고
    • Quantitative evaluation of the function of small intestinal P-glycoprotein: Comparative studies between in situ and in vitro
    • Adachi Y, Suzuki H, Sugiyama Y. 2003. Quantitative evaluation of the function of small intestinal P-glycoprotein: Comparative studies between in situ and in vitro. Pharm Res 20:1163-1169.
    • (2003) Pharm Res , vol.20 , pp. 1163-1169
    • Adachi, Y.1    Suzuki, H.2    Sugiyama, Y.3
  • 19
    • 0034017007 scopus 로고    scopus 로고
    • Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans
    • Chiou WL, Jeong HY, Chung SM, Wu TC. 2000. Evaluation of using dog as an animal model to study the fraction of oral dose absorbed of 43 drugs in humans. Pharm Res 17:135-140.
    • (2000) Pharm Res , vol.17 , pp. 135-140
    • Chiou, W.L.1    Jeong, H.Y.2    Chung, S.M.3    Wu, T.C.4
  • 20
    • 0031958251 scopus 로고    scopus 로고
    • Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-peptides
    • He YL, Murby S, Warhurst G, Gifford L, Walker D, Ayrton J, Eastmond R, Rowland M. 1998. Species differences in size discrimination in the paracellular pathway reflected by oral bioavailability of poly(ethylene glycol) and D-peptides. J Pharm Sci 87:626-633.
    • (1998) J Pharm Sci , vol.87 , pp. 626-633
    • He, Y.L.1    Murby, S.2    Warhurst, G.3    Gifford, L.4    Walker, D.5    Ayrton, J.6    Eastmond, R.7    Rowland, M.8
  • 21
    • 0036296060 scopus 로고    scopus 로고
    • Comparison of oral absorption and bioavailability of drugs between monkey and human
    • Chiou WL, Buehler PW. 2002. Comparison of oral absorption and bioavailability of drugs between monkey and human. Pharm Res 19:868-874.
    • (2002) Pharm Res , vol.19 , pp. 868-874
    • Chiou, W.L.1    Buehler, P.W.2
  • 22
    • 0025316847 scopus 로고
    • Differential transport properties of two mdr gene products are distinguished by progesterone
    • Yang CP, Cohen D, Greenberger LM, Hsu SI, Horwitz SB. 1990. Differential transport properties of two mdr gene products are distinguished by progesterone. J Biol Chem 265:10282-10288.
    • (1990) J Biol Chem , vol.265 , pp. 10282-10288
    • Yang, C.P.1    Cohen, D.2    Greenberger, L.M.3    Hsu, S.I.4    Horwitz, S.B.5
  • 24
    • 0033978102 scopus 로고    scopus 로고
    • Extensive metabolism of diltiazem and P-glycoprotein-mediated efflux of desacetyl-diltiazem (M1) by rat jejunum in vitro
    • Molden E, Christensen H, Sund RB. 2000. Extensive metabolism of diltiazem and P-glycoprotein-mediated efflux of desacetyl-diltiazem (M1) by rat jejunum in vitro. Drug Metab Dispos 28:107-109.
    • (2000) Drug Metab Dispos , vol.28 , pp. 107-109
    • Molden, E.1    Christensen, H.2    Sund, R.B.3
  • 25
    • 15344350690 scopus 로고    scopus 로고
    • Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV
    • Walker DK, Abel S, Comby P, Muirhead GJ, Nedderman AN, Smith DA. 2005. Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV. Drug Metab Dispos 33:587-595.
    • (2005) Drug Metab Dispos , vol.33 , pp. 587-595
    • Walker, D.K.1    Abel, S.2    Comby, P.3    Muirhead, G.J.4    Nedderman, A.N.5    Smith, D.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.