-
1
-
-
3042538710
-
Molecular genetics of transporters for norepinephrine, dopamine, and serotonin in behavioral traits and complex diseases
-
(Broer S. and Wagner C.A. eds) (in press)
-
Lesch, K.-P. and Murphy, D.L. Molecular genetics of transporters for norepinephrine, dopamine, and serotonin in behavioral traits and complex diseases., in Membrane Transport Diseases: Molecular Basis of Inherited Transport Defects (Broer S. and Wagner C.A. eds) (in press), 2004.
-
(2004)
Membrane Transport Diseases: Molecular Basis of Inherited Transport Defects
-
-
Lesch, K.-P.1
Murphy, D.L.2
-
2
-
-
0038644891
-
Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters
-
Androutsellis-Theotokis, A., Goldberg, N.R., Ueda, K., Beppu, T., Beckman, M.L., Das, S., Javitch, J.A., and Rudnick, G. Characterization of a functional bacterial homologue of sodium-dependent neurotransmitter transporters. J. Biol. Chem. 278, 12703-12709 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12703-12709
-
-
Androutsellis-Theotokis, A.1
Goldberg, N.R.2
Ueda, K.3
Beppu, T.4
Beckman, M.L.5
Das, S.6
Javitch, J.A.7
Rudnick, G.8
-
3
-
-
0037783318
-
Tracing pathways of transport protein evolution
-
Saier, M.H., Jr. Tracing pathways of transport protein evolution. Mol. Microbiol. 48, 1145-1156 (2003).
-
(2003)
Mol. Microbiol.
, vol.48
, pp. 1145-1156
-
-
Saier Jr., M.H.1
-
4
-
-
0031978809
-
Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4- methylenedioxy-methamphetamine (" Ecstasy") in serotonin transporter- deficient mice
-
Bengel, D., Murphy, D.L., Andrews, A.M., Wichems, C.H., Feltner, D., Heils, A., Mossner, R., Westphal, H., and Lesch, K.P. Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4- methylenedioxy-methamphetamine ("Ecstasy") in serotonin transporter- deficient mice. Mol. Pharmacol. 53, 649-55 (1998).
-
(1998)
Mol. Pharmacol.
, vol.53
, pp. 649-655
-
-
Bengel, D.1
Murphy, D.L.2
Andrews, A.M.3
Wichems, C.H.4
Feltner, D.5
Heils, A.6
Mossner, R.7
Westphal, H.8
Lesch, K.P.9
-
5
-
-
0033593033
-
A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo
-
MacKenzie, A. and Quinn, J. A serotonin transporter gene intron 2 polymorphic region, correlated with affective disorders, has allele-dependent differential enhancer-like properties in the mouse embryo. Proc. Natl. Acad. Sci. U. S. A. 96, 15251-1525 (1999).
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 15251-1525
-
-
MacKenzie, A.1
Quinn, J.2
-
6
-
-
0035073901
-
Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice
-
Gingrich, J.A. and Hen, R. Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice. Psychopharmacology (Berl.) 155, 1-10 (2001).
-
(2001)
Psychopharmacology (Berl.)
, vol.155
, pp. 1-10
-
-
Gingrich, J.A.1
Hen, R.2
-
7
-
-
0035891885
-
Genetic perspectives on the serotonin transporter
-
Murphy, D.L., Li, Q., Engel, S., Wichems, C., Andrews, A., Lesch, K.P., and Uhl, G. Genetic perspectives on the serotonin transporter. Brain Res. Bull. 56, 487-494 (2001).
-
(2001)
Brain Res. Bull.
, vol.56
, pp. 487-494
-
-
Murphy, D.L.1
Li, Q.2
Engel, S.3
Wichems, C.4
Andrews, A.5
Lesch, K.P.6
Uhl, G.7
-
8
-
-
0032560560
-
Cocaine reward models: Conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice
-
Sora, I., Wichems, C., Takahashi, N., Li, X.F., Zeng, Z., Revay, R., Lesch, K.P., Murphy, D.L., and Uhl, G.R. Cocaine reward models: Conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc. Natl. Acad. Sci. U S A 95, 7699-704 (1998).
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 7699-7704
-
-
Sora, I.1
Wichems, C.2
Takahashi, N.3
Li, X.F.4
Zeng, Z.5
Revay, R.6
Lesch, K.P.7
Murphy, D.L.8
Uhl, G.R.9
-
9
-
-
0035942241
-
Molecular mechanisms of cocaine reward: Combined dopamine and serotonin transporter knockouts eliminate cocaine place preference
-
Sora, I., Hall, F.S., Andrews, A.M. et al. Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc. Natl. Acad. Sci. U. S. A. 98, 5300-5305 (2001).
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 5300-5305
-
-
Sora, I.1
Hall, F.S.2
Andrews, A.M.3
-
10
-
-
0037110603
-
Cocaine mechanisms: Enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions
-
Hall, F.S., Li, X.F., Sora, I., Xu, F., Caron, M., Lesch, K.P., Murphy, D.L., and Uhl, G.R. Cocaine mechanisms: Enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions. Neuroscience 115, 153-161 (2002).
-
(2002)
Neuroscience
, vol.115
, pp. 153-161
-
-
Hall, F.S.1
Li, X.F.2
Sora, I.3
Xu, F.4
Caron, M.5
Lesch, K.P.6
Murphy, D.L.7
Uhl, G.R.8
-
11
-
-
0027504812
-
2-MPTP-induced depletions in serotonin and norepinephrine
-
2-MPTP-induced depletions in serotonin and norepinephrine. Eur. J. Pharmacol. 250, 215-221 (1993).
-
(1993)
Eur. J. Pharmacol.
, vol.250
, pp. 215-221
-
-
Andrews, A.M.1
Murphy, D.L.2
-
12
-
-
0027511558
-
2-MPTP): A comparative study with 2′ -CH3-MPTP and MPTP
-
2-MPTP): A comparative study with 2′ -CH3-MPTP and MPTP. J. Neurochem. 60, 1167-1170 (1993).
-
(1993)
J. Neurochem.
, vol.60
, pp. 1167-1170
-
-
Andrews, A.M.1
Murphy, D.L.2
-
13
-
-
0027731280
-
Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters
-
Schuldiner, S., Steiner-Mordoch, S., Yelin, R., Wall, S.C., and Rudnick, G. Amphetamine derivatives interact with both plasma membrane and secretory vesicle biogenic amine transporters. Mol. Pharmacol. 44, 1227-1231 (1993).
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 1227-1231
-
-
Schuldiner, S.1
Steiner-Mordoch, S.2
Yelin, R.3
Wall, S.C.4
Rudnick, G.5
-
14
-
-
0345599277
-
Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2′-aminophenyl)-1,2,3,6-tetrahydropyridine
-
Luellen, B.A., Miller, D.B., Chisnell, A.C., Murphy, D.L., O'Callaghan, J.P., and Andrews, A.M. Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2′-aminophenyl)-1,2,3,6-tetrahydropyridine. J. Pharmacol. Exp. Ther. 307, 923-931 (2003).
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.307
, pp. 923-931
-
-
Luellen, B.A.1
Miller, D.B.2
Chisnell, A.C.3
Murphy, D.L.4
O'Callaghan, J.P.5
Andrews, A.M.6
-
15
-
-
0034724340
-
Oligomerization of serotonin transporter and its functional consequences
-
Kilic, F. and Rudnick, G. Oligomerization of serotonin transporter and its functional consequences. Proc. Natl. Acad. Sci. U. S. A. 97, 3106-3111 (2000).
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 3106-3111
-
-
Kilic, F.1
Rudnick, G.2
-
17
-
-
0035830829
-
Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells
-
Schmid, J.A., Scholze, P., Kudlacek, O., Freissmuth, M., Singer, E.A., and Sitte, H.H. Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells. J. Biol. Chem. 276, 3805-3810 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3805-3810
-
-
Schmid, J.A.1
Scholze, P.2
Kudlacek, O.3
Freissmuth, M.4
Singer, E.A.5
Sitte, H.H.6
-
18
-
-
0041353145
-
Structure and mechanism of the lactose permease of Escherichia coli
-
Abramson, J., Smirnova, I., Kasho, V., Verner, G., Kaback, H.R., and Iwata, S. Structure and mechanism of the lactose permease of Escherichia coli. Science 301, 610-615 (2003).
-
(2003)
Science
, vol.301
, pp. 610-615
-
-
Abramson, J.1
Smirnova, I.2
Kasho, V.3
Verner, G.4
Kaback, H.R.5
Iwata, S.6
-
19
-
-
0041489951
-
Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli
-
Huang, Y., Lemieux, M.J., Song, J., Auer, M., and Wang, D.N. Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli. Science 301, 616-620 (2003).
-
(2003)
Science
, vol.301
, pp. 616-620
-
-
Huang, Y.1
Lemieux, M.J.2
Song, J.3
Auer, M.4
Wang, D.N.5
-
20
-
-
0242497235
-
Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside
-
Pebay-Peyroula, E., Dahout-Gonzalez, C., Kahn, R., Trezeguet, V., Lauquin, G.J., and Brandolin, G. Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature 426, 39-44 (2003).
-
(2003)
Nature
, vol.426
, pp. 39-44
-
-
Pebay-Peyroula, E.1
Dahout-Gonzalez, C.2
Kahn, R.3
Trezeguet, V.4
Lauquin, G.J.5
Brandolin, G.6
-
21
-
-
0028174014
-
Organization of the human serotonin transporter gene
-
Lesch, K.-P., Balling, U., Gross, J., Strauss, K., Wolozin, B.L., Murphy, D.L., and Riederer, P. Organization of the human serotonin transporter gene. J. Neural Transm. Gen. Sect. 95, 157-162 (1994).
-
(1994)
J. Neural Transm. Gen. Sect.
, vol.95
, pp. 157-162
-
-
Lesch, K.-P.1
Balling, U.2
Gross, J.3
Strauss, K.4
Wolozin, B.L.5
Murphy, D.L.6
Riederer, P.7
-
22
-
-
0027405191
-
Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localization
-
Ramamoorthy, S., Bauman, A.L., Moore, K.R., Han, H., Yang-Feng, T, Chang, A.S., Ganapathy, V., and Blakely, R.D. Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression, and chromosomal localization. Proc. Natl. Acad. Sci. U. S. A. 90, 2542-2546 (1993).
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 2542-2546
-
-
Ramamoorthy, S.1
Bauman, A.L.2
Moore, K.R.3
Han, H.4
Yang-Feng, T.5
Chang, A.S.6
Ganapathy, V.7
Blakely, R.D.8
-
23
-
-
0030964703
-
Alternative splicing of the human serotonin transporter gene
-
Bradley, C.C. and Blakely, R.D. Alternative splicing of the human serotonin transporter gene. J. Neurochem. 69, 1356-1367 (1997).
-
(1997)
J. Neurochem.
, vol.69
, pp. 1356-1367
-
-
Bradley, C.C.1
Blakely, R.D.2
-
24
-
-
0036062651
-
Alternative non-coding exons support serotonin transporter mRNA expression in the brain and gut
-
Ozsarac, N., Santha, E., and Hoffman, B.J. Alternative non-coding exons support serotonin transporter mRNA expression in the brain and gut. J. Neurochem. 82, 336-344 (2002).
-
(2002)
J. Neurochem.
, vol.82
, pp. 336-344
-
-
Ozsarac, N.1
Santha, E.2
Hoffman, B.J.3
-
25
-
-
0033952855
-
Modified structure of the human serotonin transporter promoter
-
Flattem, N.L. and Blakely, R.D. Modified structure of the human serotonin transporter promoter. Mol. Psychiatry 5, 110-115 (2000).
-
(2000)
Mol. Psychiatry
, vol.5
, pp. 110-115
-
-
Flattem, N.L.1
Blakely, R.D.2
-
26
-
-
0033532309
-
Functional analysis of a novel human serotonin transporter gene promoter in immortalized raphe cells
-
Mortensen, O.V., Thomassen, M., Larsen, M.B., Whittemore, S.R., and Wilborg, O. Functional analysis of a novel human serotonin transporter gene promoter in immortalized raphe cells. Brain Res. Mol. Brain Res. 68, 141-148 (1999).
-
(1999)
Brain Res. Mol. Brain Res.
, vol.68
, pp. 141-148
-
-
Mortensen, O.V.1
Thomassen, M.2
Larsen, M.B.3
Whittemore, S.R.4
Wilborg, O.5
-
27
-
-
0033429525
-
Mosaicism for a serotonin transporter gene promoter-associated deletion: Decreased recombination in depression
-
Lesch, K.P., Jatzke, S., Meyer, J., Stober, G., Okladnova, O., Mossner, R., and Riederer, P. Mosaicism for a serotonin transporter gene promoter-associated deletion: Decreased recombination in depression. J. Neural Transm. 106, 1223-1230 (1999).
-
(1999)
J. Neural Transm.
, vol.106
, pp. 1223-1230
-
-
Lesch, K.P.1
Jatzke, S.2
Meyer, J.3
Stober, G.4
Okladnova, O.5
Mossner, R.6
Riederer, P.7
-
28
-
-
0032993895
-
Presence of multiple functional polyadenylation signals and a single nucleotice polymorphism in the 3′ untranslated region of the human serotonin transporter gene
-
Battersby, S., Ogilvie, A.D., Blackwood, D.H., Shen, S., Muqit, M.M., Muir, W.J., Teague, P., Goodwin, G.M., and Harmar, A.J. Presence of multiple functional polyadenylation signals and a single nucleotice polymorphism in the 3′ untranslated region of the human serotonin transporter gene. J. Neurochem. 72, 1384-1388 (1999).
-
(1999)
J. Neurochem.
, vol.72
, pp. 1384-1388
-
-
Battersby, S.1
Ogilvie, A.D.2
Blackwood, D.H.3
Shen, S.4
Muqit, M.M.5
Muir, W.J.6
Teague, P.7
Goodwin, G.M.8
Harmar, A.J.9
-
29
-
-
0027476312
-
Isolation of a cDNA encoding the human brain serotonin transporter
-
Lesch, K.P., Wolozin, B.L., Estler, H.C., Murphy, D.L., and Riederer, P. Isolation of a cDNA encoding the human brain serotonin transporter. J. Neural Transm. Gen. Sect. 91, 67-72 (1993).
-
(1993)
J. Neural Transm. Gen. Sect.
, vol.91
, pp. 67-72
-
-
Lesch, K.P.1
Wolozin, B.L.2
Estler, H.C.3
Murphy, D.L.4
Riederer, P.5
-
30
-
-
6844252264
-
The 5-HT transporter gene-linked polymorphic region (5-HTTLPR) in evolutionary perspective: Alternative biallelic variation in rhesus monkeys
-
Lesch, K.P., Meyer, J., Glatz, K. et al. The 5-HT transporter gene-linked polymorphic region (5-HTTLPR) in evolutionary perspective: Alternative biallelic variation in rhesus monkeys. J. Neural Transm. 104, 1259-1266 (1997).
-
(1997)
J. Neural Transm.
, vol.104
, pp. 1259-1266
-
-
Lesch, K.P.1
Meyer, J.2
Glatz, K.3
-
31
-
-
0031578940
-
Cellular localization and expression of the serotonin transporter in mouse brain
-
Bengel, D., Johren, O., Andrews, A.M., Heils, A., Mossner, R., Sanvitto, G.L., Saavedra, J.M., Lesch, K.P., and Murphy, D.L. Cellular localization and expression of the serotonin transporter in mouse brain. Brain Res. 778, 338-345 (1997).
-
(1997)
Brain Res.
, vol.778
, pp. 338-345
-
-
Bengel, D.1
Johren, O.2
Andrews, A.M.3
Heils, A.4
Mossner, R.5
Sanvitto, G.L.6
Saavedra, J.M.7
Lesch, K.P.8
Murphy, D.L.9
-
32
-
-
0031889826
-
Functional characterization of the murine serotonin transporter gene promoter in serotonergic raphe neurons
-
Heils, A., Wichems, C., Mossner, R., Petri, S., Glatz, K., Bengel, D., Murphy, D.L., and Lesch, K.P. Functional characterization of the murine serotonin transporter gene promoter in serotonergic raphe neurons. J. Neurochem. 70, 932-939 (1998).
-
(1998)
J. Neurochem.
, vol.70
, pp. 932-939
-
-
Heils, A.1
Wichems, C.2
Mossner, R.3
Petri, S.4
Glatz, K.5
Bengel, D.6
Murphy, D.L.7
Lesch, K.P.8
-
33
-
-
0038708231
-
Novel variants of murine serotonin transporter mRNA and the promoter activity of its upstream site
-
Sakai, K., Hasegawa, C., Okura, M., Morikawa, O., Ueyama, T., Shirai, Y., Sakai, N., and Saito, N. Novel variants of murine serotonin transporter mRNA and the promoter activity of its upstream site. Neurosci. Lett. 342, 175-178 (2003).
-
(2003)
Neurosci. Lett.
, vol.342
, pp. 175-178
-
-
Sakai, K.1
Hasegawa, C.2
Okura, M.3
Morikawa, O.4
Ueyama, T.5
Shirai, Y.6
Sakai, N.7
Saito, N.8
-
34
-
-
0032145922
-
Genetically driven variation in serotonin uptake: Is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?
-
Lesch, K.-P. and Moessner, R. Genetically driven variation in serotonin uptake: Is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders? Biol. Psychiatry 44, 179-192 (1998).
-
(1998)
Biol. Psychiatry
, vol.44
, pp. 179-192
-
-
Lesch, K.-P.1
Moessner, R.2
-
35
-
-
0029619364
-
Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene
-
Heils, A., Teufel, A., Petri, S., Seemann, M., Bengel, D., Balling, U., Riederer, P., and Lesch, K.P. Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene. J. Neural Transm. Gen. Sect. 102, 247-254 (1995).
-
(1995)
J. Neural Transm. Gen. Sect.
, vol.102
, pp. 247-254
-
-
Heils, A.1
Teufel, A.2
Petri, S.3
Seemann, M.4
Bengel, D.5
Balling, U.6
Riederer, P.7
Lesch, K.P.8
-
36
-
-
2642595071
-
A novel allelic variant of the human serotonin transporter gene regulatory polymorphism
-
Delbruck, S.J., Wendel, B., Grunewald, I., Sander, T., Morris-Rosendahl, D., Crocq, M.A., Berrettini, W.H., and Hoehe, M.R. A novel allelic variant of the human serotonin transporter gene regulatory polymorphism. Cytogenet. Cell Genet. 79, 214-220 (1997).
-
(1997)
Cytogenet. Cell Genet.
, vol.79
, pp. 214-220
-
-
Delbruck, S.J.1
Wendel, B.2
Grunewald, I.3
Sander, T.4
Morris-Rosendahl, D.5
Crocq, M.A.6
Berrettini, W.H.7
Hoehe, M.R.8
-
37
-
-
0006463359
-
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
-
Lesch K.-P., Bengel D., Heils A. et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274, 1527-1531 (1996).
-
(1996)
Science
, vol.274
, pp. 1527-1531
-
-
Lesch, K.-P.1
Bengel, D.2
Heils, A.3
-
38
-
-
0031441095
-
Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects
-
Gelernter, J., Kranzler, H., and Cubells, J.F. Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects. Hum. Genet. 101, 243-246 (1997).
-
(1997)
Hum. Genet.
, vol.101
, pp. 243-246
-
-
Gelernter, J.1
Kranzler, H.2
Cubells, J.F.3
-
39
-
-
0033525170
-
Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets
-
Greenberg, B.D., Tolliver, T.J., Huang, S.J., Li, Q., Bengel, D., and Murphy, D.L. Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets, Am. J. Med. Genet. 88, 83-87 (1999).
-
(1999)
Am. J. Med. Genet.
, vol.88
, pp. 83-87
-
-
Greenberg, B.D.1
Tolliver, T.J.2
Huang, S.J.3
Li, Q.4
Bengel, D.5
Murphy, D.L.6
-
40
-
-
0031930348
-
Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels
-
Little, K.Y., Mclaughlin, D.P., Zhang, L. et al. Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels. Am. J. Psychiatry 155, 207-213 (1998).
-
(1998)
Am. J. Psychiatry
, vol.155
, pp. 207-213
-
-
Little, K.Y.1
Mclaughlin, D.P.2
Zhang, L.3
-
41
-
-
0032007609
-
Serotonin transporter and seasonal variation in blood serotonin in families with obsessive-compulsive disorder
-
Hanna, G.L., Himle, J.A., Curtis, G.C., Koram, D.Q., Veenstra-VanderWeele, J., Leventhal, B.L., and Cook, E.H., Jr. Serotonin transporter and seasonal variation in blood serotonin in families with obsessive-compulsive disorder. Neuropsychopharmacology 18, 102-111 (1998).
-
(1998)
Neuropsychopharmacology
, vol.18
, pp. 102-111
-
-
Hanna, G.L.1
Himle, J.A.2
Curtis, G.C.3
Koram, D.Q.4
Veenstra-VanderWeele, J.5
Leventhal, B.L.6
Cook Jr., E.H.7
-
42
-
-
0034123412
-
Serotonin transporter (5-HTT) promoter genotype may influence the prolactin response to clomipramine
-
Whale, R., Quested, D.J., Laver, D., Harrison, P.J., and Cowen, P.J. Serotonin transporter (5-HTT) promoter genotype may influence the prolactin response to clomipramine. Psychopharmacology (Berl.) 150, 120-122 (2000).
-
(2000)
Psychopharmacology (Berl.)
, vol.150
, pp. 120-122
-
-
Whale, R.1
Quested, D.J.2
Laver, D.3
Harrison, P.J.4
Cowen, P.J.5
-
43
-
-
0035826535
-
Serotonin transporter promoter polymorphism is associated with attenuated prolactin response to fenfluramine
-
Reist, C., Mazzanti, C., Vu, R., Tran, D., and Goldman, D. Serotonin transporter promoter polymorphism is associated with attenuated prolactin response to fenfluramine. Am. J. Med. Genet. 105, 363-368 (2001).
-
(2001)
Am. J. Med. Genet.
, vol.105
, pp. 363-368
-
-
Reist, C.1
Mazzanti, C.2
Vu, R.3
Tran, D.4
Goldman, D.5
-
44
-
-
0037352108
-
Allelic variation in the serotonin transporter promoter affects neuromodulatory effects of a selective serotonin transporter reuptake inhibitor (SSRI)
-
Eichhammer, P., Langguth, B., Wiegand, R., Kharraz, A., Frick, U., and Hajak, G. Allelic variation in the serotonin transporter promoter affects neuromodulatory effects of a selective serotonin transporter reuptake inhibitor (SSRI). Psychopharmacology (Berl.) 166, 294-297 (2003).
-
(2003)
Psychopharmacology (Berl.)
, vol.166
, pp. 294-297
-
-
Eichhammer, P.1
Langguth, B.2
Wiegand, R.3
Kharraz, A.4
Frick, U.5
Hajak, G.6
-
45
-
-
0036301550
-
Association between serotonin transporter gene promoter polymorphism (5HTTLPR) and behavioral responses to tryptophan depletion in healthy women with and without family history of depression
-
Neumeister A., Konstantindis A., Stastny J. et al. Association between serotonin transporter gene promoter polymorphism (5HTTLPR) and behavioral responses to tryptophan depletion in healthy women with and without family history of depression. Arch. Gen. Psychiatry 59, 613-620 (2002).
-
(2002)
Arch. Gen. Psychiatry
, vol.59
, pp. 613-620
-
-
Neumeister, A.1
Konstantindis, A.2
Stastny, J.3
-
46
-
-
1642469628
-
The serotonin transporter is a potential susceptibility factor for bipolar affective disorder
-
Collier, D.A., Arranz, M.J., Sham, P. et al. The serotonin transporter is a potential susceptibility factor for bipolar affective disorder. Neuroreport 7, 1675-1679 (1996).
-
(1996)
Neuroreport
, vol.7
, pp. 1675-1679
-
-
Collier, D.A.1
Arranz, M.J.2
Sham, P.3
-
47
-
-
0032841176
-
An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells
-
Fiskerstrand, C.E., Lovejoy, E.A., and Quinn, J.P. An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells. FEBS Lett. 458, 171-174 (1999).
-
(1999)
FEBS Lett.
, vol.458
, pp. 171-174
-
-
Fiskerstrand, C.E.1
Lovejoy, E.A.2
Quinn, J.P.3
-
48
-
-
0037270399
-
The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit
-
Lovejoy, E.A., Scott, A.C., Fiskerstrand, C.E., Bubb, V.J., and Quinn, J.P. The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit. Eur. J. Neurosci. 17, 417-420 (2003).
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 417-420
-
-
Lovejoy, E.A.1
Scott, A.C.2
Fiskerstrand, C.E.3
Bubb, V.J.4
Quinn, J.P.5
-
49
-
-
18244421874
-
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
-
Pugliese, A., Zeller, M., Fernandez, A., Jr. et al. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. Nat Genet 15, 293-7 (1997).
-
(1997)
Nat. Genet.
, vol.15
, pp. 293-297
-
-
Pugliese, A.1
Zeller, M.2
Fernandez Jr., A.3
-
50
-
-
0031018819
-
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus
-
Vafiadis, P., Bennett, S.T., Todd, J.A., Nadeau, J., Grabs, R., Goodyer, C.G., Wickramasinghe, S., Colle, E., and Polychronakos, C. Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus. Nat. Genet. 15, 289-292 (1997).
-
(1997)
Nat. Genet.
, vol.15
, pp. 289-292
-
-
Vafiadis, P.1
Bennett, S.T.2
Todd, J.A.3
Nadeau, J.4
Grabs, R.5
Goodyer, C.G.6
Wickramasinghe, S.7
Colle, E.8
Polychronakos, C.9
-
51
-
-
0242637425
-
Polymorphisms in the 5′-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression
-
Duan, J., Sanders, A.R., Molen, J.E., Martinolich, L., Mowry, B.J., Levinson, D.F., Crowe, R.R., Silverman, J.M., and Gejman, P.V. Polymorphisms in the 5′-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression. Mol. Psychiatry 8, 901-910 (2003).
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 901-910
-
-
Duan, J.1
Sanders, A.R.2
Molen, J.E.3
Martinolich, L.4
Mowry, B.J.5
Levinson, D.F.6
Crowe, R.R.7
Silverman, J.M.8
Gejman, P.V.9
-
52
-
-
85047695697
-
Transmission disequilibrium mapping at the serotonin transporter gene (SLC6A4) region in autistic disorder
-
Kim, S.J., Cox, N., Courchesne, R. et al. Transmission disequilibrium mapping at the serotonin transporter gene (SLC6A4) region in autistic disorder. Mol. Psychiatry 7, 278-288 (2002).
-
(2002)
Mol. Psychiatry
, vol.7
, pp. 278-288
-
-
Kim, S.J.1
Cox, N.2
Courchesne, R.3
-
53
-
-
85047696865
-
Segmental linkage disequilibrium within the dopamine transporter gene
-
Greenwood, T.A., Alexander, M., Keck, P.E., McElroy, S., Sadovnick, A.D., Remick, R.A., Shaw, S.H., and Kelsoe, J.R. Segmental linkage disequilibrium within the dopamine transporter gene. Mol. Psychiatry 7, 165-173 (2002).
-
(2002)
Mol. Psychiatry
, vol.7
, pp. 165-173
-
-
Greenwood, T.A.1
Alexander, M.2
Keck, P.E.3
McElroy, S.4
Sadovnick, A.D.5
Remick, R.A.6
Shaw, S.H.7
Kelsoe, J.R.8
-
54
-
-
0035071541
-
Screening a large reference sample to identify very low frequency sequence variants: Comparisons between two genes
-
Glatt, C.E., DeYoung, J.A., Delgado, S., Service, S.K., Giacomini, K.M., Edwards, R.H., Risch, N., and Freimer, N.B. Screening a large reference sample to identify very low frequency sequence variants: Comparisons between two genes. Nat. Genet 27, 435-438 (2001).
-
(2001)
Nat. Genet.
, vol.27
, pp. 435-438
-
-
Glatt, C.E.1
DeYoung, J.A.2
Delgado, S.3
Service, S.K.4
Giacomini, K.M.5
Edwards, R.H.6
Risch, N.7
Freimer, N.B.8
-
55
-
-
0242637392
-
Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype
-
Ozaki, N., Goldman, D., Kaye, W.H., Plotnicov, K., Greenberg, B.D., Lappalainen, J., Rudnick, G., and Murphy, D.L. Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype. Mol. Psychiatry 8, 933-936 (2003).
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 933-936
-
-
Ozaki, N.1
Goldman, D.2
Kaye, W.H.3
Plotnicov, K.4
Greenberg, B.D.5
Lappalainen, J.6
Rudnick, G.7
Murphy, D.L.8
-
56
-
-
0042343721
-
A human serotonin transporter mutation causes constitutive activation of transport activity
-
Kilic, F., Murphy, D.L., and Rudnick, G. A human serotonin transporter mutation causes constitutive activation of transport activity. Mol. Pharmacol 64, 440-446 (2003).
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 440-446
-
-
Kilic, F.1
Murphy, D.L.2
Rudnick, G.3
-
57
-
-
0041341961
-
Center stage for the serotonin transporter: A gain-of-function polymorphism in persons with obsessive-compulsive disorder
-
Torres, G.E. and Caron, M.G. Center stage for the serotonin transporter: a gain-of-function polymorphism in persons with obsessive-compulsive disorder. Mol. Pharmacol. 64, 196-198 (2003).
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 196-198
-
-
Torres, G.E.1
Caron, M.G.2
-
58
-
-
0029823635
-
Systematic screening for mutations in the coding region of the human serotonin transporter (5-HTT) gene using PCR and DGGE
-
Di Bella, D., Catalano, M., Balling, U., Smeraldi, E., and Lesch, K.P. Systematic screening for mutations in the coding region of the human serotonin transporter (5-HTT) gene using PCR and DGGE. Am. J. Med. Genet. 67, 541-545 (1996).
-
(1996)
Am. J. Med. Genet.
, vol.67
, pp. 541-545
-
-
Di Bella, D.1
Catalano, M.2
Balling, U.3
Smeraldi, E.4
Lesch, K.P.5
-
59
-
-
0031824568
-
Localization and dynamic regulation of biogenic amine transporters in the mammalian central nervous system
-
Hoffman, B.J., Hansson, S.R., Mezey, E., and Palkovits, M. Localization and dynamic regulation of biogenic amine transporters in the mammalian central nervous system. Front. Neuroendocrinol. 19, 187-231 (1998).
-
(1998)
Front. Neuroendocrinol.
, vol.19
, pp. 187-231
-
-
Hoffman, B.J.1
Hansson, S.R.2
Mezey, E.3
Palkovits, M.4
-
60
-
-
0032509799
-
Serotonin transporter messenger RNA in the developing rat brain: Early expression in serotonergic neurons and transient expression in non-serotonergic neurons
-
Hansson, S.R., Mezey, E., and Hoffman, B.J. Serotonin transporter messenger RNA in the developing rat brain: Early expression in serotonergic neurons and transient expression in non-serotonergic neurons. Neuroscience 83, 1185-1201 (1998).
-
(1998)
Neuroscience
, vol.83
, pp. 1185-1201
-
-
Hansson, S.R.1
Mezey, E.2
Hoffman, B.J.3
-
64
-
-
0041335224
-
11C]-DASB positron emission tomography studies of the serotonin transporter in human brain
-
11C]-DASB positron emission tomography studies of the serotonin transporter in human brain. J. Cereb. Blood Flow Metab. 23, 1096-1112 (2003).
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 1096-1112
-
-
Ichise, M.1
Liow, J.S.2
Lu, J.Q.3
-
68
-
-
0035157572
-
11C]-DASB PET imaging study
-
11C]-DASB PET imaging study. Am. J. Psychiatry 158, 1843-1849 (2001).
-
(2001)
Am. J. Psychiatry
, vol.158
, pp. 1843-1849
-
-
Meyer, J.H.1
Wilson, A.A.2
Ginovart, N.3
Goulding, V.4
Hussey, D.5
Hood, K.6
Houle, S.7
-
69
-
-
1642498182
-
Pharmacologic and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine, (AFM) and 3-amino-4[2-(dimethyl-aminomethylphenylthio)] benzonitrile, (DASB)
-
Li, Q., Ma L., Innis, R.B., Seneca, N., Ichise, M., Huang, H., Laruelle, M., and Murphy, D.L. Pharmacologic and genetic characterization of two selective serotonin transporter ligands: 2-[2-(dimethylaminomethylphenylthio)]-5-fluoromethylphenylamine, (AFM) and 3-amino-4[2-(dimethyl-aminomethylphenylthio)] benzonitrile, (DASB). J. Pharmacol. Exp. Ther. 308, 481-486 (2004).
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.308
, pp. 481-486
-
-
Li, Q.1
Ma, L.2
Innis, R.B.3
Seneca, N.4
Ichise, M.5
Huang, H.6
Laruelle, M.7
Murphy, D.L.8
-
70
-
-
17144466384
-
Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice
-
Montanez, S., Owens, W.A., Gould, G.G., Murphy, D.L., and Daws, L.C. Exaggerated effect of fluvoxamine in heterozygote serotonin transporter knockout mice. J. Neurochem. 86, 210-219 (2003).
-
(2003)
J. Neurochem.
, vol.86
, pp. 210-219
-
-
Montanez, S.1
Owens, W.A.2
Gould, G.G.3
Murphy, D.L.4
Daws, L.C.5
-
71
-
-
0034606327
-
Multimarker haplotypes within the serotonin transporter gene suggest evidence of an association with bipolar disorder
-
Mynett-Johnson, L., Kealey, C., Claffey, E., Curtis, D., Bouchier-Hayes, L., Powell, C., and McKeon, P. Multimarker haplotypes within the serotonin transporter gene suggest evidence of an association with bipolar disorder. Am. J. Med. Genet. 96, 845-849 (2000).
-
(2000)
Am. J. Med. Genet.
, vol.96
, pp. 845-849
-
-
Mynett-Johnson, L.1
Kealey, C.2
Claffey, E.3
Curtis, D.4
Bouchier-Hayes, L.5
Powell, C.6
McKeon, P.7
-
72
-
-
2342520299
-
Serotonin transporter gene and autism: A haplotype analysis in an Irish autistic population
-
Jan 6 [Epub ahead of print]
-
Conroy, J., Meally, E., Kearney, G., Fitzgerald, M., Gill, M., and Gallagher, L. Serotonin transporter gene and autism: A haplotype analysis in an Irish autistic population. Mol. Psychiatry (2004). Jan 6 [Epub ahead of print].
-
(2004)
Mol. Psychiatry
-
-
Conroy, J.1
Meally, E.2
Kearney, G.3
Fitzgerald, M.4
Gill, M.5
Gallagher, L.6
-
73
-
-
0141857859
-
Association of the serotonin transporter gene with sudden infant death syndrome: A haplotype analysis
-
Weese-Mayer, D.E., Zhou, L., Berry-Kravis, E.M., Maher, B.S., Silvestri J.M., and Marazita, M.L. Association of the serotonin transporter gene with sudden infant death syndrome: A haplotype analysis. Am. J. Med. Genet. 122A, 238-245 (2003).
-
(2003)
Am. J. Med. Genet.
, vol.122 A
, pp. 238-245
-
-
Weese-Mayer, D.E.1
Zhou, L.2
Berry-Kravis, E.M.3
Maher, B.S.4
Silvestri, J.M.5
Marazita, M.L.6
-
74
-
-
0041346384
-
A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders
-
Anguelova, M., Benkelfat, C., and Turecki, G. A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: I. Affective disorders. Mol. Psychiatry 8, 574-591 (2003).
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 574-591
-
-
Anguelova, M.1
Benkelfat, C.2
Turecki, G.3
-
75
-
-
0036046157
-
Monoamine transporter gene structure an polymorphisms in relation to psychiatric and other complex disorders
-
Hahn, M.K. and Blakely, R.D. Monoamine transporter gene structure an polymorphisms in relation to psychiatric and other complex disorders. Pharmacogenomics J. 2, 217-235 (2002).
-
(2002)
Pharmacogenomics J.
, vol.2
, pp. 217-235
-
-
Hahn, M.K.1
Blakely, R.D.2
-
76
-
-
0035503323
-
Physiological genomics of antidepressant targets: Keeping the periphery in mind
-
Blakely, R.D. Physiological genomics of antidepressant targets: Keeping the periphery in mind. J. Neurosci. 21, 8319-8323 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 8319-8323
-
-
Blakely, R.D.1
-
77
-
-
2542463073
-
Diagnostic interview assessed neuropsychiatric disorder comorbidity in 334 individuals wiuth obsessive-compulsive disorder
-
(in press)
-
LaSalle V.H., Cromer K.R., Nelson K.N., Kazuba D., Justement L. and Murphy D.L. Diagnostic interview assessed neuropsychiatric disorder comorbidity in 334 individuals wiuth obsessive-compulsive disorder. Depression and Anxiety (in press).
-
Depression and Anxiety
-
-
LaSalle, V.H.1
Cromer, K.R.2
Nelson, K.N.3
Kazuba, D.4
Justement, L.5
Murphy, D.L.6
-
78
-
-
0042121277
-
A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior
-
Anguelova, M., Benkelfat, C., and Turecki, G. A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior. Mol. Psychiatry 8, 646-653 (2003).
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 646-653
-
-
Anguelova, M.1
Benkelfat, C.2
Turecki, G.3
-
79
-
-
0037624040
-
Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
-
Epidemiology-based report of hSERT x environment interaction in >800 individuals
-
Caspi, A., Sugden, K., Moffitt, T.E. et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301, 386-389 (2003). Epidemiology-based report of hSERT x environment interaction in >800 individuals.
-
(2003)
Science
, vol.301
, pp. 386-389
-
-
Caspi, A.1
Sugden, K.2
Moffitt, T.E.3
-
80
-
-
0037135137
-
Serotonin transporter genetic variation and the response of the human amygdala
-
Hariri, A.R., Mattay, V.S., Tessitore, A., Kolachana, B., Fera, F., Goldman, D., Egan, M.F., and Weinberger, D.R. Serotonin transporter genetic variation and the response of the human amygdala. Science 297, 400-403 (2002).
-
(2002)
Science
, vol.297
, pp. 400-403
-
-
Hariri, A.R.1
Mattay, V.S.2
Tessitore, A.3
Kolachana, B.4
Fera, F.5
Goldman, D.6
Egan, M.F.7
Weinberger, D.R.8
-
81
-
-
0036892142
-
Exaggerated adrenomedullary response to immobilization in mice with a targeted disruption of the serotonin transporter gene
-
Tjurmina, O.A., Armando, I., Saavedra, J.M., Goldstein, D.S., and Murphy, D.L. Exaggerated adrenomedullary response to immobilization in mice with a targeted disruption of the serotonin transporter gene. Endocrinology 143, 4520-4526 (2002).
-
(2002)
Endocrinology
, vol.143
, pp. 4520-4526
-
-
Tjurmina, O.A.1
Armando, I.2
Saavedra, J.M.3
Goldstein, D.S.4
Murphy, D.L.5
-
82
-
-
0345305851
-
Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders
-
Murphy, D.L., Uhl, G.R., Holmes, A., Ren-Patterson, R., Hall, F.S., Sora, I., Detera-Wadleigh, S., and Lesch K.P. Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. Genes Brain Behav. 2, 350-364 (2003).
-
(2003)
Genes Brain Behav.
, vol.2
, pp. 350-364
-
-
Murphy, D.L.1
Uhl, G.R.2
Holmes, A.3
Ren-Patterson, R.4
Hall, F.S.5
Sora, I.6
Detera-Wadleigh, S.7
Lesch, K.P.8
-
83
-
-
0034776773
-
Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension
-
Eddahibi S., Humbert M., Fadel E. et al. Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension. J. Clin. Invest. 108, 1141-1150 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1141-1150
-
-
Eddahibi, S.1
Humbert, M.2
Fadel, E.3
-
84
-
-
9444287592
-
Appetite-suppressant drugs and the risk of primary pulmonary hypertension
-
International Primary Pulmonary Hypertension Study Group
-
Abenhaim L., Moride Y., Brenot F. et al. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International Primary Pulmonary Hypertension Study Group. N. Engl. J. Med. 335, 609-616 (1996).
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 609-616
-
-
Abenhaim, L.1
Moride, Y.2
Brenot, F.3
-
85
-
-
0030876952
-
Valvular heart disease associated with fenfluramine-phentermine
-
Connolly, H.M., Crary, J.L., McGoon, M.D., Hensrud, D.D., Edwards, B.S., Edwards, W.D., and Schaff, H.V. Valvular heart disease associated with fenfluramine-phentermine. N. Engl. J. Med. 337, 581-588 (1997).
-
(1997)
N. Engl. J. Med.
, vol.337
, pp. 581-588
-
-
Connolly, H.M.1
Crary, J.L.2
McGoon, M.D.3
Hensrud, D.D.4
Edwards, B.S.5
Edwards, W.D.6
Schaff, H.V.7
-
86
-
-
0032971293
-
Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin
-
Eddahibi, S., Fabre, V., Boni, C., Martres, M.P., Raffestin, B., Hamon, M., and Adnot, S. Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin. Circ. Res. 84, 329-336 (1999).
-
(1999)
Circ. Res.
, vol.84
, pp. 329-336
-
-
Eddahibi, S.1
Fabre, V.2
Boni, C.3
Martres, M.P.4
Raffestin, B.5
Hamon, M.6
Adnot, S.7
-
87
-
-
0034096980
-
Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene
-
Eddahibi, S., Hanoun, N., Lanfumey, L., Lesch, K.P., Raffestin, B., Hamon, M., and Adnot, S. Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene. J. Clin. Invest. 105, 1555-1562 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1555-1562
-
-
Eddahibi, S.1
Hanoun, N.2
Lanfumey, L.3
Lesch, K.P.4
Raffestin, B.5
Hamon, M.6
Adnot, S.7
-
88
-
-
0142085751
-
Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease
-
Eddahibi, S., Chaouat, A., Morrell, N. et al. Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease. Circulation 108, 1839-1844 (2003).
-
(2003)
Circulation
, vol.108
, pp. 1839-1844
-
-
Eddahibi, S.1
Chaouat, A.2
Morrell, N.3
-
89
-
-
0034778907
-
Linking a serotonin transporter polymorphism to vascular smooth muscle proliferation in patients with primary pulmonary hypertension
-
Rabinovitch, M. Linking a serotonin transporter polymorphism to vascular smooth muscle proliferation in patients with primary pulmonary hypertension. J. Clin. Invest. 108, 1109-1111 (2001).
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1109-1111
-
-
Rabinovitch, M.1
-
90
-
-
0037173073
-
Serotonin transporter gene polymorphism and myocardial infarction: Etude Cas-Temoins de I'lnfarctus du Myocarde (ECTIM)
-
Fumeron, F., Betoulle, D., Nicaud, V., Evans, A., Kee, F., Ruidavets, J.B., Arveiler, D., Luc, G., and Cambien, F. Serotonin transporter gene polymorphism and myocardial infarction: Etude Cas-Temoins de I'lnfarctus du Myocarde (ECTIM). Circulation 105, 2943-2945 (2002).
-
(2002)
Circulation
, vol.105
, pp. 2943-2945
-
-
Fumeron, F.1
Betoulle, D.2
Nicaud, V.3
Evans, A.4
Kee, F.5
Ruidavets, J.B.6
Arveiler, D.7
Luc, G.8
Cambien, F.9
-
91
-
-
0345700822
-
5-Hydroxytryptamine 5-HT2A receptor and 5-hydroxytryptamine transporter polymorphisms in acute myocardial infarction
-
Coto, E., Reguero, J.R., Alvarez, V. et al. 5-Hydroxytryptamine 5-HT2A receptor and 5-hydroxytryptamine transporter polymorphisms in acute myocardial infarction. Clin. Sci. (Lond.) 104, 241-245 (2003).
-
(2003)
Clin. Sci. (Lond.)
, vol.104
, pp. 241-245
-
-
Coto, E.1
Reguero, J.R.2
Alvarez, V.3
-
92
-
-
0038503196
-
Effect of antidepressants and their relative affinity for the serotonin transporter on the risk of myocardial infarction
-
Sauer, W.H., Berlin, J.A., and Kimmel, S.E. Effect of antidepressants and their relative affinity for the serotonin transporter on the risk of myocardial infarction. Circulation 108, 32-36 (2003).
-
(2003)
Circulation
, vol.108
, pp. 32-36
-
-
Sauer, W.H.1
Berlin, J.A.2
Kimmel, S.E.3
-
93
-
-
0032798743
-
Association of the serotonin transporter gene with serum cholesterol levels and heart disease
-
Comings, D.E., MacMurray, J.P., Gonzalez, N., Ferry, L., and Peters, W.R. Association of the serotonin transporter gene with serum cholesterol levels and heart disease. Mol. Genet. Metab. 67, 248-253 (1999).
-
(1999)
Mol. Genet. Metab.
, vol.67
, pp. 248-253
-
-
Comings, D.E.1
MacMurray, J.P.2
Gonzalez, N.3
Ferry, L.4
Peters, W.R.5
-
94
-
-
0035089470
-
Central nervous system serotonin function and cardiovascular responses to stress
-
Williams, R.B., Marchuk, D.A., Gadde, K.M. et al. Central nervous system serotonin function and cardiovascular responses to stress. Psychosom. Med. 63, 300-305 (2001).
-
(2001)
Psychosom. Med.
, vol.63
, pp. 300-305
-
-
Williams, R.B.1
Marchuk, D.A.2
Gadde, K.M.3
-
95
-
-
0141746347
-
Allelic variation in the serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cardiovascular reactivity in young adult male and female twins of European-American descent
-
McCaffery, J.M., Bleil, M., Pogue-Geile, M.F., Ferrell, R.E., and Manuck, S.B. Allelic variation in the serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cardiovascular reactivity in young adult male and female twins of European-American descent. Psychosom. Med. 65, 721-728 (2003).
-
(2003)
Psychosom. Med.
, vol.65
, pp. 721-728
-
-
McCaffery, J.M.1
Bleil, M.2
Pogue-Geile, M.F.3
Ferrell, R.E.4
Manuck, S.B.5
-
96
-
-
0032919084
-
Roles played by 5-hydroxytryptamine in the physiology of the bowel
-
Gershon, M.D. Roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment. Pharmacol. Ther. 13 Suppl 2, 15-30 (1999).
-
(1999)
Aliment. Pharmacol. Ther.
, vol.13
, Issue.SUPPL. 2
, pp. 15-30
-
-
Gershon, M.D.1
-
97
-
-
0036310957
-
Serotonin transporter gene polymorphism in irritable bowel syndrome
-
Pata, C., Erdal, M.E., Derici, E., Yazar, A., Kanik, A., and Ulu, O. Serotonin transporter gene polymorphism in irritable bowel syndrome. Am. J. Gastroenterol. 97, 1780-1784 (2002).
-
(2002)
Am. J. Gastroenterol.
, vol.97
, pp. 1780-1784
-
-
Pata, C.1
Erdal, M.E.2
Derici, E.3
Yazar, A.4
Kanik, A.5
Ulu, O.6
-
98
-
-
0036325415
-
Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome
-
Camilleri, M., Atanasova, E., Carlson, P.J., Ahmad, U., Kim, H.J., Viramontes, B.E., McKinzie, S., and Urrutia, R. Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome. Gastroenterology 123, 425-432 (2002).
-
(2002)
Gastroenterology
, vol.123
, pp. 425-432
-
-
Camilleri, M.1
Atanasova, E.2
Carlson, P.J.3
Ahmad, U.4
Kim, H.J.5
Viramontes, B.E.6
McKinzie, S.7
Urrutia, R.8
-
99
-
-
0035882382
-
Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters
-
Mouse model with IBS features
-
Chen, J.J., Li, Z., Pan, H., Murphy, D.L., Tamir, H., Koepsell, H., and Gershon, M.D. Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters. J. Neurosci. 21, 6348-6361. (2001). Mouse model with IBS features.
-
(2001)
J. Neurosci.
, vol.21
, pp. 6348-6361
-
-
Chen, J.J.1
Li, Z.2
Pan, H.3
Murphy, D.L.4
Tamir, H.5
Koepsell, H.6
Gershon, M.D.7
-
100
-
-
0036890028
-
Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporter
-
Liu, M.T., Rayport, S., Jiang, Y., Murphy, D.L., and Gershon M.D. Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporter. Am. J. Physiol. Gastrointest. Liver Physiol. 283, G1398-G1411 (2002).
-
(2002)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.283
-
-
Liu, M.T.1
Rayport, S.2
Jiang, Y.3
Murphy, D.L.4
Gershon, M.D.5
-
101
-
-
0034606204
-
Search for bipolar disorder susceptibility loci: The application of a modified genome scan concentrating on gene-rich regions
-
Murphy, V.E., Mynett-Johnson, L.A., Claffey, E., Bergin, P., McAuliffe, M., Kealey, C., and McKeon, P. Search for bipolar disorder susceptibility loci: The application of a modified genome scan concentrating on gene-rich regions. Am. J. Med. Genet. 96, 728-732 (2000).
-
(2000)
Am. J. Med. Genet.
, vol.96
, pp. 728-732
-
-
Murphy, V.E.1
Mynett-Johnson, L.A.2
Claffey, E.3
Bergin, P.4
McAuliffe, M.5
Kealey, C.6
McKeon, P.7
-
102
-
-
0037938810
-
Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12
-
Liu, J., Juo, S.H., Dewan, A. et al. Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12. Mol. Psychiatry 8, 333-342 (2003).
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 333-342
-
-
Liu, J.1
Juo, S.H.2
Dewan, A.3
-
103
-
-
0038389850
-
Genomewide linkage analyses of bipolar disorder: A new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative
-
Dick, D.M., Foroud, T., Flury, L. et al. Genomewide linkage analyses of bipolar disorder: A new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative. Am. J. Hum. Genet. 73, 107-114 (2003).
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 107-114
-
-
Dick, D.M.1
Foroud, T.2
Flury, L.3
-
104
-
-
0036384203
-
Evidence that variation at the serotonin transporter gene influences susceptibility to attention deficit hyperactivity disorder (ADHD): Analysis and pooled analysis
-
Kent, L., Doerry, U., Hardy, E. et al. Evidence that variation at the serotonin transporter gene influences susceptibility to attention deficit hyperactivity disorder (ADHD): Analysis and pooled analysis. Mol. Psychiatry 7, 908-912 (2002).
-
(2002)
Mol. Psychiatry
, vol.7
, pp. 908-912
-
-
Kent, L.1
Doerry, U.2
Hardy, E.3
-
105
-
-
0036239098
-
A genomewide scan for loci involved in attention-deficit/hyperactivity disorder
-
Fisher, S.E., Francks, C., McCracken, J.T. et al. A genomewide scan for loci involved in attention-deficit/hyperactivity disorder. Am. J. Hum. Genet. 70, 1183-1196 (2002).
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 1183-1196
-
-
Fisher, S.E.1
Francks, C.2
McCracken, J.T.3
-
106
-
-
0036201494
-
Genomewide scan of hoarding in sib pairs in which both sibs have Gilles de la Tourette syndrome
-
Zhang, H., Leckman, J.F., Pauls, D.L., Tsai, C.P., Kidd, K.K., and Campos, M.R. Genomewide scan of hoarding in sib pairs in which both sibs have Gilles de la Tourette syndrome. Am. J. Hum. Genet. 70, 896-904 (2002).
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 896-904
-
-
Zhang, H.1
Leckman, J.F.2
Pauls, D.L.3
Tsai, C.P.4
Kidd, K.K.5
Campos, M.R.6
-
107
-
-
0142059641
-
A genomewide screen of 345 families for autism-susceptibility loci
-
Yonan A.L., Alarcon M., Cheng R. et al. A genomewide screen of 345 families for autism-susceptibility loci. Am. J. Hum. Genet. 73, 886-897 (2003).
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 886-897
-
-
Yonan, A.L.1
Alarcon, M.2
Cheng, R.3
-
108
-
-
0034883367
-
A genomewide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q, and 16p
-
IMGSAC
-
IMGSAC. A genomewide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q, and 16p. Am. J. Hum. Genet. 69, 570-581 (2001).
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 570-581
-
-
-
109
-
-
0031669441
-
Role of the serotonin transporter promoter polymorphism in anxiety-related traits
-
Mazzanti, C.M., Lappalainen, J., Long, J.C., Bengel, D., Naukkarinen, H., Eggert, M., Virkkunen, M., Linnoila, M., and Goldman, D. Role of the serotonin transporter promoter polymorphism in anxiety-related traits. Arch. Gen. Psychiatry 55, 936-940 (1998).
-
(1998)
Arch. Gen. Psychiatry
, vol.55
, pp. 936-940
-
-
Mazzanti, C.M.1
Lappalainen, J.2
Long, J.C.3
Bengel, D.4
Naukkarinen, H.5
Eggert, M.6
Virkkunen, M.7
Linnoila, M.8
Goldman, D.9
-
110
-
-
0035028249
-
Human fear conditioning is related to dopaminergic and serotonergic biological markers
-
Garpenstrand, H., Annas, P., Ekblom, J., Oreland, L., and Fredrikson, M. Human fear conditioning is related to dopaminergic and serotonergic biological markers. Behav. Neurosci. 115, 358-364 (2001).
-
(2001)
Behav. Neurosci.
, vol.115
, pp. 358-364
-
-
Garpenstrand, H.1
Annas, P.2
Ekblom, J.3
Oreland, L.4
Fredrikson, M.5
-
111
-
-
0033866640
-
Evaluating gene x psychological risk factor effects in the pathogenesis of anxiety: A new model approach
-
Schmidt, N.B., Storey, J., Greenberg, B.D., Santiago, H.T., Li, Q., and Murphy, D.L. Evaluating gene x psychological risk factor effects in the pathogenesis of anxiety: A new model approach. J. Abnorm. Psychol. 109, 308-320 (2000).
-
(2000)
J. Abnorm. Psychol.
, vol.109
, pp. 308-320
-
-
Schmidt, N.B.1
Storey, J.2
Greenberg, B.D.3
Santiago, H.T.4
Li, Q.5
Murphy, D.L.6
-
112
-
-
0032993957
-
Visceral chemical nociception in mice lacking mu-opioid receptors: Effects of morphine, SNC80 and U-50,488
-
Sora, I., Li, X.F., Funada, M., Kinsey, S., and Uhl, G.R. Visceral chemical nociception in mice lacking mu-opioid receptors: Effects of morphine, SNC80 and U-50,488. Eur. J. Pharmacol. 366, R3-R5 (1999).
-
(1999)
Eur. J. Pharmacol.
, vol.366
-
-
Sora, I.1
Li, X.F.2
Funada, M.3
Kinsey, S.4
Uhl, G.R.5
-
113
-
-
0037428768
-
Altered rapid eye movement sleep timing in serotonin transporter knockout mice
-
Wisor, J.P., Wurts, S.W., Hall, F.S., Lesch, K.P., Murphy, D.L., Uhl, G.R., and Edgar, D.M. Altered rapid eye movement sleep timing in serotonin transporter knockout mice. Neuroreport 14, 233-238 (2003).
-
(2003)
Neuroreport
, vol.14
, pp. 233-238
-
-
Wisor, J.P.1
Wurts, S.W.2
Hall, F.S.3
Lesch, K.P.4
Murphy, D.L.5
Uhl, G.R.6
Edgar, D.M.7
-
114
-
-
2342502792
-
Age-related obesity in 5-HT transporter deficient mice
-
Abstract 4071. Society for Neuroscience, New Orleans, LA
-
Holmes, A., Yang, R.J., Murphy, D.L., and Crawley J.N. Age-related obesity in 5-HT transporter deficient mice. Abstract 4071. Society for Neuroscience, New Orleans, LA (2003).
-
(2003)
-
-
Holmes, A.1
Yang, R.J.2
Murphy, D.L.3
Crawley, J.N.4
-
115
-
-
0037439622
-
Absence of thermal hyperalgesia in serotonin transporter-deficient mice
-
Vogel, C., Mossner, R., Gerlach, M., Heinemann, T., Murphy, D.L., Riederer, P., Lesch, K.P., and Sommer, C. Absence of thermal hyperalgesia in serotonin transporter-deficient mice. J. Neurosci. 23, 708-715 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 708-715
-
-
Vogel, C.1
Mossner, R.2
Gerlach, M.3
Heinemann, T.4
Murphy, D.L.5
Riederer, P.6
Lesch, K.P.7
Sommer, C.8
-
116
-
-
0242391960
-
Abnormal behavioral phenotypes of serotonin transporter knockout mice: Parallels with human anxiety and depression
-
Holmes, A., Murphy, D.L., and Crawley, J.N. Abnormal behavioral phenotypes of serotonin transporter knockout mice: Parallels with human anxiety and depression. Biol. Psychiatry 54, 953-959 (2003).
-
(2003)
Biol. Psychiatry
, vol.54
, pp. 953-959
-
-
Holmes, A.1
Murphy, D.L.2
Crawley, J.N.3
-
117
-
-
0242600079
-
Mice lacking the serotonin transporter exhibit 5-HT1A receptor-mediated abnormalities in tests for anxiety-like behavior
-
Holmes, A., Yang, R.J., Lesch, K.-P., Crawley, J.N., and Murphy, D.L. Mice lacking the serotonin transporter exhibit 5-HT1A receptor-mediated abnormalities in tests for anxiety-like behavior. Neuropsychopharmacology 28, 2077-2088 (2003).
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 2077-2088
-
-
Holmes, A.1
Yang, R.J.2
Lesch, K.-P.3
Crawley, J.N.4
Murphy, D.L.5
-
118
-
-
1542283785
-
Association between allelic variation of serotonin transporter function and neuroticism in anxious cluster personality disorders
-
Jacob, C.P., Strobel, A., Holhenberger, K., Ringel, T., Gutknecht, L., Reif, A., Brocke, B., and Lesch, K.-P. Association between allelic variation of serotonin transporter function and neuroticism in anxious cluster personality disorders. Am. J. Psychiatry 161, 569-522 (2004).
-
(2004)
Am. J. Psychiatry
, vol.161
, pp. 522-569
-
-
Jacob, C.P.1
Strobel, A.2
Holhenberger, K.3
Ringel, T.4
Gutknecht, L.5
Reif, A.6
Brocke, B.7
Lesch, K.-P.8
-
119
-
-
0027198748
-
Serotonin and cardiac morphogenesis in the mouse embryo
-
Yavarone, M.S., Shuey, D.L., Tamir, H., Sadler, T.W., and Lauder, J.M. Serotonin and cardiac morphogenesis in the mouse embryo. Teratology 47, 573-584 (1993).
-
(1993)
Teratology
, vol.47
, pp. 573-584
-
-
Yavarone, M.S.1
Shuey, D.L.2
Tamir, H.3
Sadler, T.W.4
Lauder, J.M.5
-
120
-
-
0035449944
-
Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release
-
Persico, A.M., Mengual, E., Moessner, R. et al. Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release. J. Neurosci. 21, 6862-6873 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 6862-6873
-
-
Persico, A.M.1
Mengual, E.2
Moessner, R.3
-
121
-
-
0038147541
-
Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression
-
Manji, H.K., Quiroz, J.A., Sporn, J., Payne, J.L., Denicoff, K., Gray, N.A., Zarate, C.A., Jr., and Charney, D.S. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biol. Psychiatry 53, 707-742 (2003).
-
(2003)
Biol. Psychiatry
, vol.53
, pp. 707-742
-
-
Manji, H.K.1
Quiroz, J.A.2
Sporn, J.3
Payne, J.L.4
Denicoff, K.5
Gray, N.A.6
Zarate Jr., C.A.7
Charney, D.S.8
-
122
-
-
0031802343
-
Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive-compulsive disorder
-
McDougle, C.J., Epperson, C.N., Price, L.H., and Gelernter, J. Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive-compulsive disorder. Mol. Psychiatry 3, 270-273 (1998).
-
(1998)
Mol. Psychiatry
, vol.3
, pp. 270-273
-
-
McDougle, C.J.1
Epperson, C.N.2
Price, L.H.3
Gelernter, J.4
-
123
-
-
0031685344
-
Possible serotonergic mechanisms underlying the antidepressant and anti-obsessive-compulsive disorder responses
-
Blier, P. and de Montigny, C. Possible serotonergic mechanisms underlying the antidepressant and anti-obsessive-compulsive disorder responses. Biol. Psychiatry 44, 313-323 (1998).
-
(1998)
Biol. Psychiatry
, vol.44
, pp. 313-323
-
-
Blier, P.1
de Montigny, C.2
-
124
-
-
0037421584
-
Inheritance and drug response
-
Weinshilboum, R. Inheritance and drug response. N. Engl. J. Med. 348, 529-537 (2003).
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 529-537
-
-
Weinshilboum, R.1
-
125
-
-
0034966799
-
Pharmacogenetics: A new diagnostic tool in the management of antidepressive drug therapy
-
Steimer, W., Muller, B., Leucht, S., and Kissling, W. Pharmacogenetics: A new diagnostic tool in the management of antidepressive drug therapy. Clin. Chim. Acta 308, 33-41 (2001).
-
(2001)
Clin. Chim. Acta
, vol.308
, pp. 33-41
-
-
Steimer, W.1
Muller, B.2
Leucht, S.3
Kissling, W.4
-
126
-
-
0029064096
-
Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis
-
Dahl, M.L., Johansson, I., Bertilsson, L., Ingelman-Sundberg, M., and Sjoqvist, F. Ultrarapid hydroxylation of debrisoquine in a Swedish population. Analysis of the molecular genetic basis. J. Pharmacol. Exp. Ther. 274, 516-520 (1995).
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.274
, pp. 516-520
-
-
Dahl, M.L.1
Johansson, I.2
Bertilsson, L.3
Ingelman-Sundberg, M.4
Sjoqvist, F.5
-
127
-
-
0037040397
-
Pharmacogenetics in affective disorders
-
Serretti, A., Lilli, R., and Smeraldi, E. Pharmacogenetics in affective disorders. Eur. J. Pharmacol. 438, 117-128 (2002).
-
(2002)
Eur. J. Pharmacol.
, vol.438
, pp. 117-128
-
-
Serretti, A.1
Lilli, R.2
Smeraldi, E.3
-
129
-
-
0034677021
-
Serotonin transporter gene polymorphism and antidepressant response
-
Kim. D.K., Lim. S.W., Lee. S., Sohn. S.E., Kim. S., Hahn. C.G.. and Carroll. B.J. Serotonin transporter gene polymorphism and antidepressant response. Neuroreport 11, 215-219 (2000).
-
(2000)
Neuroreport
, vol.11
, pp. 215-219
-
-
Kim, D.K.1
Lim, S.W.2
Lee, S.3
Sohn, S.E.4
Kim, S.5
Hahn, C.G.6
Carroll, B.J.7
-
130
-
-
0036140426
-
Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluovoxamine in Japanese depressed patient
-
Yoshida K., Ito K., Takahashi H. et al. Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluovoxamine in Japanese depressed patient. Prog. Neuropsychopharmacol. Biol. Psychiatry 158, 383-386 (2002).
-
(2002)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.158
, pp. 383-386
-
-
Yoshida, K.1
Ito, K.2
Takahashi, H.3
-
131
-
-
0033009323
-
Association of a polymorphism of the 5HT2A receptor gene promoter region with alcohol dependence
-
Nakamura, T., Matsushita, S., Nishiguchi, N., Kimura, M., Yoshino, A., and Higuchi S. Association of a polymorphism of the 5HT2A receptor gene promoter region with alcohol dependence. Mol. Psychiatry 4, 85-88 (1999).
-
(1999)
Mol. Psychiatry
, vol.4
, pp. 85-88
-
-
Nakamura, T.1
Matsushita, S.2
Nishiguchi, N.3
Kimura, M.4
Yoshino, A.5
Higuchi, S.6
-
132
-
-
0022178173
-
Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations
-
Nakamura, K., Goto, F., Ray, W.A., McAllister, C.B., Jacqz, E., Wilkinson, G.R., and Branch, R.A. Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations. Clin. Pharmacol. Ther. 38, 402-408 (1985).
-
(1985)
Clin. Pharmacol. Ther.
, vol.38
, pp. 402-408
-
-
Nakamura, K.1
Goto, F.2
Ray, W.A.3
McAllister, C.B.4
Jacqz, E.5
Wilkinson, G.R.6
Branch, R.A.7
-
133
-
-
0031228024
-
Obsessive compulsive disorder, response to serotonin reuptake inhibitors and the serotonin transporter gene
-
Billett, E.A., Richter, M.A., King, N., Heils, A., Lesch, K.-P., and Kennedy, J.L. Obsessive compulsive disorder, response to serotonin reuptake inhibitors and the serotonin transporter gene. Mol. Psychiatry 2, 40340-6 (1997).
-
(1997)
Mol. Psychiatry
, vol.2
, pp. 40340-40346
-
-
Billett, E.A.1
Richter, M.A.2
King, N.3
Heils, A.4
Lesch, K.-P.5
Kennedy, J.L.6
-
134
-
-
0036367043
-
Obsessive-compulsive disorder, 5-HTTLPR polymorphism and treatment response
-
Di Bella, D., Erzegovesi, S., Cavallini, M.C., and Bellodi, L. Obsessive-compulsive disorder, 5-HTTLPR polymorphism and treatment response. Pharmacogenomics J. 2, 176-181 (2002).
-
(2002)
Pharmacogenomics J.
, vol.2
, pp. 176-181
-
-
Di Bella, D.1
Erzegovesi, S.2
Cavallini, M.C.3
Bellodi, L.4
-
135
-
-
0032731373
-
Association of the serotonin transporter promoter regulatory region and obsessive-compulsive disorder
-
Bengel, D., Greenberg, B.D., Corá-Locatelli, G., Altemus, M., Heils, A., Li, Q., and Murphy, D.L. Association of the serotonin transporter promoter regulatory region and obsessive-compulsive disorder. Mol. Psychiatry 4, 463-466 (1999).
-
(1999)
Mol. Psychiatry
, vol.4
, pp. 463-466
-
-
Bengel, D.1
Greenberg, B.D.2
Corá-Locatelli, G.3
Altemus, M.4
Heils, A.5
Li, Q.6
Murphy, D.L.7
-
136
-
-
0036897940
-
Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter
-
Holmes, A., Yang, R.J., Murphy, D.L., and Crawley, J.N. Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacology 27, 914-923 (2002).
-
(2002)
Neuropsychopharmacology
, vol.27
, pp. 914-923
-
-
Holmes, A.1
Yang, R.J.2
Murphy, D.L.3
Crawley, J.N.4
-
137
-
-
0142157564
-
Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment
-
Perlis, R.H., Mischoulon, D., Smoller, J.W., Wan, Y.J., Lamon-Fava, S., Lin, K.M., Rosenbaum, J.F., and Fava, M. Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment. Biol. Psychiatry 54, 879-883 (2003).
-
(2003)
Biol. Psychiatry
, vol.54
, pp. 879-883
-
-
Perlis, R.H.1
Mischoulon, D.2
Smoller, J.W.3
Wan, Y.J.4
Lamon-Fava, S.5
Lin, K.M.6
Rosenbaum, J.F.7
Fava, M.8
-
138
-
-
0034998460
-
The role of serotonin transporter protein gene in antidepressant-induced mania in bipolar disorder: Preliminary findings
-
Mundo, E., Walker, M., Cate, T., Macciardi, F., and Kennedy, J.L. The role of serotonin transporter protein gene in antidepressant-induced mania in bipolar disorder: Preliminary findings. Arch. Gen. Psychiatry 58, 539-544 (2001).
-
(2001)
Arch. Gen. Psychiatry
, vol.58
, pp. 539-544
-
-
Mundo, E.1
Walker, M.2
Cate, T.3
Macciardi, F.4
Kennedy, J.L.5
-
139
-
-
0037636573
-
Antidepressant-induced mania, rapid cycling and the serotonin transporter gene polymorphism
-
Rousseva A., Henry C., van den Bulke D. et al. Antidepressant-induced mania, rapid cycling and the serotonin transporter gene polymorphism. Pharmacogenomics J. 3, 101-104 (2003).
-
(2003)
Pharmacogenomics J.
, vol.3
, pp. 101-104
-
-
Rousseva, A.1
Henry, C.2
van den Bulke, D.3
-
140
-
-
0015396512
-
The "switch process" in manic-depressive illness. 3. Theoretical implications
-
Bunney, W.E., Jr., Goodwin, F.K., and Murphy, D.L. The "switch process" in manic-depressive illness. 3. Theoretical implications. Arch. Gen. Psychiatry 27, 312-317 (1972).
-
(1972)
Arch. Gen. Psychiatry
, vol.27
, pp. 312-317
-
-
Bunney Jr., W.E.1
Goodwin, F.K.2
Murphy, D.L.3
-
141
-
-
0015214581
-
Regular induction of hypomania by L-clopa in "bipolar" manic-depressive patients
-
Murphy, D.L., Brodie, H.K., Goodwin, F.K., and Bunney, W.E., Jr. Regular induction of hypomania by L-clopa in "bipolar" manic-depressive patients. Nature 229, 135-136 (1971).
-
(1971)
Nature
, vol.229
, pp. 135-136
-
-
Murphy, D.L.1
Brodie, H.K.2
Goodwin, F.K.3
Bunney Jr., W.E.4
-
142
-
-
0035185636
-
Understanding the neurobiology of suicidal behavior
-
Kamali, M., Oquendo, M.A., and Mann, J.J. Understanding the neurobiology of suicidal behavior. Depress. Anxiety 14, 164-176 (2001).
-
(2001)
Depress. Anxiety
, vol.14
, pp. 164-176
-
-
Kamali, M.1
Oquendo, M.A.2
Mann, J.J.3
-
143
-
-
0642371335
-
Pharmacogenetics of antidepressant medication intolerance
-
Murphy, G.M., Jr., Kremer, C., Rodrigues, H.E., and Schatzberg, A.F. Pharmacogenetics of antidepressant medication intolerance. Am. J. Psychiatry 160, 1830-1835 (2003).
-
(2003)
Am. J. Psychiatry
, vol.160
, pp. 1830-1835
-
-
Murphy Jr., G.M.1
Kremer, C.2
Rodrigues, H.E.3
Schatzberg, A.F.4
-
144
-
-
0019972555
-
Possible development of the serotonin syndrome in man
-
Insel, T.R., Roy, B.F., Cohen, R.M., and Murphy, D.L. Possible development of the serotonin syndrome in man. Am. J. Psychiatry 139, 954-955 (1982).
-
(1982)
Am. J. Psychiatry
, vol.139
, pp. 954-955
-
-
Insel, T.R.1
Roy, B.F.2
Cohen, R.M.3
Murphy, D.L.4
-
145
-
-
0017326440
-
The behavioral toxicity of monoamine oxidase-inhibiting antidepressants
-
Murphy, D.L. The behavioral toxicity of monoamine oxidase-inhibiting antidepressants. Adv. Pharmacol. Chemother. 14, 71-105 (1977).
-
(1977)
Adv. Pharmacol. Chemother.
, vol.14
, pp. 71-105
-
-
Murphy, D.L.1
-
146
-
-
0041385736
-
Paroxetine (Paxil®, Seroxat®): Increased risk of suicide in pediatric patients
-
Wooltorton, E. Paroxetine (Paxil®, Seroxat®): Increased risk of suicide in pediatric patients. CMA J. 169, 446 (2003).
-
(2003)
CMA J.
, vol.169
, pp. 446
-
-
Wooltorton, E.1
-
147
-
-
0035069918
-
Serotonin transporter gene variation is a risk factor for sudden infant death syndrome in the Japanese population
-
Narita, N., Narita, M., Takashima, S., Nakayama, M., Nagai, T., and Olkado, N. Serotonin transporter gene variation is a risk factor for sudden infant death syndrome in the Japanese population. Pediatrics 107, 690-692 (2001).
-
(2001)
Pediatrics
, vol.107
, pp. 690-692
-
-
Narita, N.1
Narita, M.2
Takashima, S.3
Nakayama, M.4
Nagai, T.5
Olkado, N.6
-
148
-
-
0030830590
-
Serotonin transporter (5-HTT) gene variants associated with autism?
-
Klauck, S.M., Poustka, F., Benner, A., Lesch, K.P., and Poustka, A. Serotonin transporter (5-HTT) gene variants associated with autism? Hum. Mol. Genet. 6, 2233-2238 (1997).
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 2233-2238
-
-
Klauck, S.M.1
Poustka, F.2
Benner, A.3
Lesch, K.P.4
Poustka, A.5
-
149
-
-
0035826536
-
Evidence for an association with the serotonin transporter promoter region polymorphism and autism
-
Yirmiya, N., Pilowsky, T., Nemanov, L., Arbelle, S., Feinsilver, T., Fried, I., and Ebstein, R.P. Evidence for an association with the serotonin transporter promoter region polymorphism and autism. Am. J. Med. Genet. 105, 381-386 (2001).
-
(2001)
Am. J. Med. Genet.
, vol.105
, pp. 381-386
-
-
Yirmiya, N.1
Pilowsky, T.2
Nemanov, L.3
Arbelle, S.4
Feinsilver, T.5
Fried, I.6
Ebstein, R.P.7
-
150
-
-
8244234472
-
Evidence of linkage between the serotonin transporter and autistic behavior
-
Cook, E.H., Jr., Courchesne, R., Lord, C., Cox, N.J., Yan, S., Lincoln A., Haas R., Courchesne, E., and Leventhal, B.L. Evidence of linkage between the serotonin transporter and autistic behavior. Mol. Psychiatry 2, 247-250 (1997).
-
(1997)
Mol. Psychiatry
, vol.2
, pp. 247-250
-
-
Cook Jr., E.H.1
Courchesne, R.2
Lord, C.3
Cox, N.J.4
Yan, S.5
Lincoln, A.6
Haas, R.7
Courchesne, E.8
Leventhal, B.L.9
-
151
-
-
0034001134
-
Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency
-
Shannon, J.R., Flattem, N.L., Jordan, J., Jacob, G., Black, B.K., Biaggioni, I., Blakely, R.D., and Robertson, D. Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency. N. Engl. J. Med. 342, 541-549 (2000).
-
(2000)
N. Engl. J. Med.
, vol.342
, pp. 541-549
-
-
Shannon, J.R.1
Flattem, N.L.2
Jordan, J.3
Jacob, G.4
Black, B.K.5
Biaggioni, I.6
Blakely, R.D.7
Robertson, D.8
-
152
-
-
0038118243
-
A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters
-
Hahn, M.K., Robertson, D., and Blakely, R.D. A mutation in the human norepinephrine transporter gene (SLC6A2) associated with orthostatic intolerance disrupts surface expression of mutant and wild-type transporters. J. Neurosci. 23, 4470-4478 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 4470-4478
-
-
Hahn, M.K.1
Robertson, D.2
Blakely, R.D.3
-
153
-
-
0036220528
-
Pharmacological properties of the naturally occurring Ala457Pro variant of the human norepinephrine transporter
-
Paczkowski, F.A., Bonisch, H., and Bryan-Lluka, L.J. Pharmacological properties of the naturally occurring Ala457Pro variant of the human norepinephrine transporter. Pharmacogenetics 12, 165-173 (2002).
-
(2002)
Pharmacogenetics
, vol.12
, pp. 165-173
-
-
Paczkowski, F.A.1
Bonisch, H.2
Bryan-Lluka, L.J.3
-
154
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M.H., Lavedan, C., Leroy, E. et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047 (1997).
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
-
155
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate, A., Chartier-Harlin, M.C., Mullan, M. et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349, 704-706 (1991).
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
-
156
-
-
0344827206
-
Mutation of MEF2A in an inherited disorder with features of coronary artery disease
-
Wang, L., Fan, C., Topol, S.E., Topol, E.J., and Wang, Q. Mutation of MEF2A in an inherited disorder with features of coronary artery disease. Science 302, 1578-1581 (2003).
-
(2003)
Science
, vol.302
, pp. 1578-1581
-
-
Wang, L.1
Fan, C.2
Topol, S.E.3
Topol, E.J.4
Wang, Q.5
-
157
-
-
0032991552
-
Characterization of single-nucleotide polymorphisms in coding regions of human genes
-
Cargill M., Altshuler D., Ireland J. et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat. Genet. 22, 231-238 (1999).
-
(1999)
Nat. Genet.
, vol.22
, pp. 231-238
-
-
Cargill, M.1
Altshuler, D.2
Ireland, J.3
-
158
-
-
0028931804
-
Primary structure of the serotonin transporter in unipolar depression and bipolar disorder
-
Lesch, K.P., Gross, J., Franzek, E., Wolozin, B.L., Riederer, P., and Murphy, D.L. Primary structure of the serotonin transporter in unipolar depression and bipolar disorder. Biol. Psychiatry 37, 215-223 (1995).
-
(1995)
Biol. Psychiatry
, vol.37
, pp. 215-223
-
-
Lesch, K.P.1
Gross, J.2
Franzek, E.3
Wolozin, B.L.4
Riederer, P.5
Murphy, D.L.6
|