-
1
-
-
31444441701
-
New approaches to antidepressant drug discovery: Beyond monoamines
-
DOI 10.1038/nrn1846, PII NRN1846
-
Berton O, Nestler EJ. New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci 2006; 7: 137-151. (Pubitemid 43151600)
-
(2006)
Nature Reviews Neuroscience
, vol.7
, Issue.2
, pp. 137-151
-
-
Berton, O.1
Nestler, E.J.2
-
2
-
-
1242263295
-
From monoamines to genomic targets: A paradigm shift for drug discovery in depression
-
Wong ML, Licinio J. From monoamines to genomic targets: a paradigm shift for drug discovery in depression. Nat Rev Drug Discov 2004; 3: 136-151. (Pubitemid 38239775)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.2
, pp. 136-151
-
-
Wong, M.-L.1
Licinio, J.2
-
3
-
-
0033520363
-
How do antidepressants work? Prospects for genetic analysis of drug mechanisms
-
DOI 10.1016/S0092-8674(00)80042-2
-
Schafer WR. How do antidepressants work? Prospects for genetic analysis of drug mechanisms. Cell 1999; 98: 551-554. (Pubitemid 29418946)
-
(1999)
Cell
, vol.98
, Issue.5
, pp. 551-554
-
-
Schafer, W.R.1
-
4
-
-
0028172409
-
Adenosine A3 receptors regulate serotonin transport via nitric oxide and cGMP
-
Miller KJ, Hoffman BJ. Adenosine A3 receptors regulate serotonin transport via nitric oxide and cGMP. J Biol Chem 1994; 269: 27351-27356.
-
(1994)
J Biol Chem
, vol.269
, pp. 27351-27356
-
-
Miller, K.J.1
Hoffman, B.J.2
-
5
-
-
23844454012
-
Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase
-
DOI 10.1073/pnas.0501432102
-
Prasad HC, Zhu CB, McCauley JL, Samuvel DJ, Ramamoorthy S, Shelton RC et al. Human serotonin transporter variants display altered sensitivity to protein kinase G and p38 mitogen-activated protein kinase. Proc Natl Acad Sci USA 2005; 102: 11545-11550. (Pubitemid 41153856)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.32
, pp. 11545-11550
-
-
Prasad, H.C.1
Zhu, C.-B.2
McCauley, J.L.3
Samuvel, D.J.4
Ramamoorthy, S.5
Shelton, R.C.6
Hewlett, W.A.7
Sutcliffe, J.S.8
Blakely, R.D.9
-
6
-
-
78650825589
-
A population-specific HTR2B stop codon predisposes to severe impulsivity
-
Bevilacqua L, Doly S, Kaprio J, Yuan Q, Tikkanen R, Paunio T et al. A population-specific HTR2B stop codon predisposes to severe impulsivity. Nature 2010; 468: 1061-1066.
-
(2010)
Nature
, vol.468
, pp. 1061-1066
-
-
Bevilacqua, L.1
Doly, S.2
Kaprio, J.3
Yuan, Q.4
Tikkanen, R.5
Paunio, T.6
-
7
-
-
33748648565
-
2B receptor signaling in serotonergic neuronal cells
-
DOI 10.1096/fj.06-5724com
-
Launay JM, Schneider B, Loric S, Da Prada M, Kellermann O. Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells. FASEB J 2006; 20: 1843-1854. (Pubitemid 44933798)
-
(2006)
FASEB Journal
, vol.20
, Issue.11
, pp. 1843-1854
-
-
Launay, J.-M.1
Schneider, B.2
Loric, S.3
Da Prada, M.4
Kellermann, O.5
-
8
-
-
71049194851
-
Role of serotonin via 5-HT2B receptors in the reinforcing effects of MDMA in mice
-
Doly S, Bertran-Gonzalez J, Callebert J, Bruneau A, Banas SM, Belmer A et al. Role of serotonin via 5-HT2B receptors in the reinforcing effects of MDMA in mice. PLoS ONE 2009; 4: e7952.
-
(2009)
PLoS ONE
, vol.4
-
-
Doly, S.1
Bertran-Gonzalez, J.2
Callebert, J.3
Bruneau, A.4
Banas, S.M.5
Belmer, A.6
-
9
-
-
40849142489
-
2B receptors are required for 3,4- methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro
-
DOI 10.1523/JNEUROSCI.5723-07.2008
-
Doly S, Valjent E, Setola V, Callebert J, Herve D, Launay JM et al. Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine- induced hyperlocomotion and 5-HT release in vivo and in vitro. J Neurosci 2008; 28: 2933-2940. (Pubitemid 351398883)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.11
, pp. 2933-2940
-
-
Doly, S.1
Valjent, E.2
Setola, V.3
Callebert, J.4
Herve, D.5
Launay, J.-M.6
Maroteaux, L.7
-
10
-
-
78650176305
-
Deconstructing antiobesity compound action: Requirement of serotonin 5-HT2B receptors for dexfenfluramine anorectic effects
-
Banas S, Doly S, Boutourlinsky K, Diaz S, Belmer A, Callebert J et al. Deconstructing antiobesity compound action: requirement of serotonin 5-HT2B receptors for dexfenfluramine anorectic effects. Neuropsychopharmacology 2011; 36: 423-433.
-
(2011)
Neuropsychopharmacology
, vol.36
, pp. 423-433
-
-
Banas, S.1
Doly, S.2
Boutourlinsky, K.3
Diaz, S.4
Belmer, A.5
Callebert, J.6
-
11
-
-
79958105768
-
Implication of 5-HT2B receptors in the serotonin syndrome
-
Diaz S, Maroteaux L. Implication of 5-HT2B receptors in the serotonin syndrome. Neuropharmacology 2011; 61: 495-502.
-
(2011)
Neuropharmacology
, vol.61
, pp. 495-502
-
-
Diaz, S.1
Maroteaux, L.2
-
12
-
-
73649115601
-
A longitudinal study of 5-HToutflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain
-
Popa D, Cerdan J, Reperant C, Guiard BP, Guilloux JP, David DJ et al. A longitudinal study of 5-HToutflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain. Eur J Pharmacol 2010; 628: 83-90.
-
(2010)
Eur J Pharmacol
, vol.628
, pp. 83-90
-
-
Popa, D.1
Cerdan, J.2
Reperant, C.3
Guiard, B.P.4
Guilloux, J.P.5
David, D.J.6
-
13
-
-
0033681079
-
Antidepressant-like behavioral effects mediated by 5-hydroxytryptamine2C receptors
-
Cryan JF, Lucki I. Antidepressant-like behavioral effects mediated by 5-hydroxytryptamine2C receptors. J Pharmacol Exp Ther 2000; 295: 1120-1126.
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 1120-1126
-
-
Cryan, J.F.1
Lucki, I.2
-
14
-
-
0034670389
-
5-HT4 receptors do not mediate the antidepressant-like behavioral effects of fluoxetine in a modified forced swim test
-
Cryan JF, Lucki I. 5-HT4 receptors do not mediate the antidepressant-like behavioral effects of fluoxetine in a modified forced swim test. Eur J Pharmacol 2000; 409: 295-299.
-
(2000)
Eur J Pharmacol
, vol.409
, pp. 295-299
-
-
Cryan, J.F.1
Lucki, I.2
-
15
-
-
34548246547
-
4) Receptor Agonists Are Putative Antidepressants with a Rapid Onset of Action
-
DOI 10.1016/j.neuron.2007.07.041, PII S0896627307006186
-
Lucas G, Rymar VV, Du J, Mnie-Filali O, Bisgaard C, Manta S et al. Serotonin(4) (5-HT(4)) receptor agonists are putative antidepressants with a rapid onset of action. Neuron 2007; 55: 712-725. (Pubitemid 47334877)
-
(2007)
Neuron
, vol.55
, Issue.5
, pp. 712-725
-
-
Lucas, G.1
Rymar, V.V.2
Du, J.3
Mnie-Filali, O.4
Bisgaard, C.5
Manta, S.6
Lambas-Senas, L.7
Wiborg, O.8
Haddjeri, N.9
Pineyro, G.10
Sadikot, A.F.11
Debonnel, G.12
-
16
-
-
31144476933
-
2A receptor function by chronic administration of selective serotonin reuptake inhibitors
-
DOI 10.1016/j.brainres.2005.10.075, PII S0006899305015350
-
Yamauchi M, Miyara T, Matsushima T, Imanishi T. Desensitization of 5-HT2A receptor function by chronic administration of selective serotonin reuptake inhibitors. Brain Res 2006; 1067: 164-169. (Pubitemid 43133085)
-
(2006)
Brain Research
, vol.1067
, Issue.1
, pp. 164-169
-
-
Yamauchi, M.1
Miyara, T.2
Matsushima, T.3
Imanishi, T.4
-
17
-
-
0042528720
-
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants
-
DOI 10.1126/science.1083328
-
Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, Dulawa S et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 2003; 301: 805-809. (Pubitemid 36962615)
-
(2003)
Science
, vol.301
, Issue.5634
, pp. 805-809
-
-
Santarelli, L.1
Saxe, M.2
Gross, C.3
Surget, A.4
Battaglia, F.5
Dulawa, S.6
Weisstaub, N.7
Lee, J.8
Duman, R.9
Arancio, O.10
Belzung, C.11
Hen, R.12
-
18
-
-
77949387830
-
Open questions in current models of antidepressant action
-
Tanti A, Belzung C. Open questions in current models of antidepressant action. Br J Pharmacol 2010; 159: 1187-1200.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 1187-1200
-
-
Tanti, A.1
Belzung, C.2
-
19
-
-
0034662967
-
Serotonin 2B receptor is required for heart development
-
Nebigil CG, Choi D-S, Dierich A, Hickel P, Le Meur M, Messaddeq N et al. Serotonin 2B receptor is required for heart development. Proc Natl Acad Sci USA 2000; 97: 9508-9513. (Pubitemid 30650806)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.17
, pp. 9508-9513
-
-
Nebigil, C.G.1
Choi, D.-S.2
Dierich, A.3
Hickel, P.4
Le Meur, M.5
Messaddeq, N.6
Launay, J.-M.7
Maroteaux, L.8
-
20
-
-
0031978809
-
Altered brain serotonin homeostasis and locomotor insensitivity to 3,4- methylenedioxymethamphetamine ('ecstasy') in serotonin transporter-deficient mice
-
Bengel D, Murphy DL, Andrews AM, Wichems CH, Feltner D, Heils A et al. Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ('Ecstasy') in serotonin transporter-deficient mice. Mol Pharmacol 1998; 53: 649-655. (Pubitemid 28196486)
-
(1998)
Molecular Pharmacology
, vol.53
, Issue.4
, pp. 649-655
-
-
Bengel, D.1
Murphy, D.L.2
Andrews, A.M.3
Wichems, C.H.4
Feltner, D.5
Heils, A.6
Mossner, R.7
Westphal, H.8
Lesch, K.-P.9
-
21
-
-
0037461749
-
Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior
-
DOI 10.1016/S0896-6273(02)01167-4
-
Hendricks TJ, Fyodorov DV, Wegman LJ, Lelutiu NB, Pehek EA, Yamamoto B et al. Pet-1 ETS gene plays a critical role in 5-HT neuron development and is required for normal anxiety-like and aggressive behavior. Neuron 2003; 37: 233-247. (Pubitemid 36143819)
-
(2003)
Neuron
, vol.37
, Issue.2
, pp. 233-247
-
-
Hendricks, T.J.1
Fyodorov, D.V.2
Wegman, L.J.3
Lelutiu, N.B.4
Pehek, E.A.5
Yamamoto, B.6
Silver, J.7
Weeber, E.J.8
Sweatt, J.D.9
Deneris, E.S.10
-
22
-
-
0035017384
-
Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice
-
DOI 10.1007/s002130100694
-
Lucki I, Dalvi A, Mayorga AJ. Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice. Psychopharmacology (Berl) 2001; 155: 315-322. (Pubitemid 32477289)
-
(2001)
Psychopharmacology
, vol.155
, Issue.3
, pp. 315-322
-
-
Lucki, I.1
Dalvi, A.2
Mayorga, A.J.3
-
23
-
-
28044464062
-
A genetic approach to access serotonin neurons for in vivo and in vitro studies
-
DOI 10.1073/pnas.0504510102
-
Scott MM, Wylie CJ, Lerch JK, Murphy R, Lobur K, Herlitze S et al. A genetic approach to access serotonin neurons for in vivo and in vitro studies. Proc Natl Acad Sci USA 2005; 102: 16472-16477. (Pubitemid 41688938)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.45
, pp. 16472-16477
-
-
Scott, M.M.1
Wylie, C.J.2
Lerch, J.K.3
Murphy, R.4
Lobur, K.5
Herlitze, S.6
Jiang, W.7
Conlon, R.A.8
Strowbridge, B.W.9
Deneris, E.S.10
-
24
-
-
65449128179
-
Characterization of Nkx6-2-derived neocortical interneuron lineages
-
Sousa VH, Miyoshi G, Hjerling-Leffler J, Karayannis T, Fishell G. Characterization of Nkx6-2-derived neocortical interneuron lineages. Cereb Cortex 2009; 19(Suppl 1): i1-i10.
-
(2009)
Cereb Cortex
, vol.19
, Issue.SUPPL. 1
-
-
Sousa, V.H.1
Miyoshi, G.2
Hjerling-Leffler, J.3
Karayannis, T.4
Fishell, G.5
-
25
-
-
0031008195
-
Molecular and physiological diversity of cortical nonpyramidal cells
-
Cauli B, Audinat E, Lambolez B, Angulo MC, Ropert N, Tsuzuki K et al. Molecular and physiological diversity of cortical nonpyramidal cells. J Neurosci 1997; 17: 3894-3906. (Pubitemid 27200611)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.10
, pp. 3894-3906
-
-
Cauli, B.1
Audinat, E.2
Lambolez, B.3
Angulo, M.C.4
Ropert, N.5
Tsuzuki, K.6
Hestrin, S.7
Rossier, J.8
-
26
-
-
0028151041
-
Ectopic induction and reorganization of Wnt-1 expression in quail/chick chimeras
-
Bally-Cuif L, Wassef M. Ectopic induction and reorganization of Wnt-1 expression in quail/chick chimeras. Development 1994; 120: 3379-3394. (Pubitemid 24366984)
-
(1994)
Development
, vol.120
, Issue.12
, pp. 3379-3394
-
-
Bally-Cuif, L.1
Wassef, M.2
-
27
-
-
84859165369
-
Selective siRNA-mediated suppression of 5-HT(1A) autoreceptors evokes strong anti-depressant-like effects
-
in press
-
Bortolozzi A, Castañ é A, Semakova J, Santana N, Alvarado G, Cortés R et al. Selective siRNA-mediated suppression of 5-HT(1A) autoreceptors evokes strong anti-depressant-like effects. Mol Psychiatry 2011 (in press).
-
(2011)
Mol Psychiatry
-
-
Bortolozzi, A.1
Castañé, A.2
Semakova, J.3
Santana, N.4
Alvarado, G.5
Cortés, R.6
-
28
-
-
0034671366
-
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
-
Malberg JE, Eisch AJ, Nestler EJ, Duman RS. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 2000; 20: 9104-9110. (Pubitemid 32042912)
-
(2000)
Journal of Neuroscience
, vol.20
, Issue.24
, pp. 9104-9110
-
-
Malberg, J.E.1
Eisch, A.J.2
Nestler, E.J.3
Duman, R.S.4
-
29
-
-
56549103593
-
Fluoxetinemediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation
-
Li B, Zhang S, Zhang H, Nu W, Cai L, Hertz L et al. Fluoxetinemediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation. Psychopharmacology (Berl) 2008; 201: 443-458.
-
(2008)
Psychopharmacology (Berl)
, vol.201
, pp. 443-458
-
-
Li, B.1
Zhang, S.2
Zhang, H.3
Nu, W.4
Cai, L.5
Hertz, L.6
-
30
-
-
34247872922
-
Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test
-
DOI 10.1007/s00213-007-0728-9
-
O'Leary OF, Bechtholt AJ, Crowley JJ, Hill TE, Page ME, Lucki I. Depletion of serotonin and catecholamines block the acute behavioral response to different classes of antidepressant drugs in the mouse tail suspension test. Psychopharmacology (Berl) 2007; 192: 357-371. (Pubitemid 46701581)
-
(2007)
Psychopharmacology
, vol.192
, Issue.3
, pp. 357-371
-
-
O'Leary, O.F.1
Bechtholt, A.J.2
Crowley, J.J.3
Hill, T.E.4
Page, M.E.5
Lucki, I.6
-
31
-
-
26944447116
-
Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter
-
DOI 10.1016/j.neuropharm.2005.08.010, PII S0028390805003102, New Perspectives in Neurotransmitter Transporter Biology
-
Kim DK, Tolliver TJ, Huang SJ, Martin BJ, Andrews AM, Wichems C et al. Altered serotonin synthesis, turnover and dynamic regulation in multiple brain regions of mice lacking the serotonin transporter. Neuropharmacology 2005; 49: 798-810. (Pubitemid 41483886)
-
(2005)
Neuropharmacology
, vol.49
, Issue.6
, pp. 798-810
-
-
Kim, D.-K.1
Tolliver, T.J.2
Huang, S.-J.3
Martin, B.J.4
Andrews, A.M.5
Wichems, C.6
Holmes, A.7
Lesch, K.-P.8
Murphy, D.L.9
-
32
-
-
73549116494
-
5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants
-
Richardson-Jones JW, Craige CP, Guiard BP, Stephen A, Metzger KL, Kung HF et al. 5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants. Neuron 2010; 65: 40-52.
-
(2010)
Neuron
, vol.65
, pp. 40-52
-
-
Richardson-Jones, J.W.1
Craige, C.P.2
Guiard, B.P.3
Stephen, A.4
Metzger, K.L.5
Kung, H.F.6
-
33
-
-
73549095954
-
Altered function of the serotonin 1A autoreceptor and the antidepressant response
-
Blier P. Altered function of the serotonin 1A autoreceptor and the antidepressant response. Neuron 2010; 65: 1-2.
-
(2010)
Neuron
, vol.65
, pp. 1-2
-
-
Blier, P.1
-
34
-
-
65649125633
-
Neurogenesis-dependent and-independent effects of fluoxetine in an animal model of anxiety/depression
-
David DJ, Samuels BA, Rainer Q, Wang J-W, Marsteller D, Mendez I et al. Neurogenesis-dependent and-independent effects of fluoxetine in an animal model of anxiety/depression. Neuron 2009; 62: 479-493.
-
(2009)
Neuron
, vol.62
, pp. 479-493
-
-
David, D.J.1
Samuels, B.A.2
Rainer, Q.3
Wang, J.-W.4
Marsteller, D.5
Mendez, I.6
-
35
-
-
13944257674
-
Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus
-
DOI 10.1523/JNEUROSCI.3741-04.2005
-
Sairanen M, Lucas G, Ernfors P, Castrén M, Castrén E. Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus. J Neurosci 2005; 25: 1089-1094. (Pubitemid 40268949)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.5
, pp. 1089-1094
-
-
Sairanen, M.1
Lucas, G.2
Ernfors, P.3
Castren, M.4
Castren, E.5
-
36
-
-
0022229760
-
Presynaptic 5-HT autoreceptors on serotonergic cell bodies and/or dendrites but not terminals are of the 5-HT(1A) subtype
-
DOI 10.1016/0014-2999(85)90099-8
-
Verge D, Daval G, Patey A, Gozlan H, el Mestikawy S, Hamon M. Presynaptic 5-HT autoreceptors on serotonergic cell bodies and/or dendrites but not terminals are of the 5-HT1A subtype. Eur J Pharmacol 1985; 113: 463-464. (Pubitemid 16249855)
-
(1985)
European Journal of Pharmacology
, vol.113
, Issue.3
, pp. 463-464
-
-
Verge, D.1
Daval, G.2
Patey, A.3
-
37
-
-
0035957507
-
2 receptors differentially regulate the excitability of 5-HT-containing neurones of the guinea pig dorsal raphe nucleus in vitro
-
DOI 10.1016/S0006-8993(01)02221-1, PII S0006899301022211
-
Craven RM, Grahame-Smith DG, Newberry NR. 5-HT1A and 5-HT2 receptors differentially regulate the excitability of 5-HTcontaining neurones of the guinea pig dorsal raphe nucleus in vitro. Brain Res 2001; 899: 159-168. (Pubitemid 32324157)
-
(2001)
Brain Research
, vol.899
, Issue.1-2
, pp. 159-168
-
-
Craven, R.M.1
Grahame-Smith, D.G.2
Newberry, N.R.3
-
38
-
-
3142620973
-
Influence of SERTPR STin2 in the serotonin transporter gene on the effect of selective serotonin reuptake inhibitors in depression: A systematic review
-
DOI 10.1038/sj.mp.4001488
-
Smits KM, Smits LJ, Schouten JS, Stelma FF, Nelemans P, Prins MH. Influence of SERTPR and STin2 in the serotonin transporter gene on the effect of selective serotonin reuptake inhibitors in depression: a systematic review. Mol Psychiatry 2004; 9: 433-441. (Pubitemid 38903501)
-
(2004)
Molecular Psychiatry
, vol.9
, Issue.5
, pp. 433-441
-
-
Smits, K.M.1
Smits, L.J.M.2
Schouten, J.S.A.G.3
Stelma, F.F.4
Nelemans, P.5
Prins, M.H.6
-
39
-
-
33846017361
-
Drugs and valvular heart disease
-
Roth BL. Drugs and valvular heart disease. N Engl J Med 2007; 356: 6-9.
-
(2007)
N Engl J Med
, vol.356
, pp. 6-9
-
-
Roth, B.L.1
-
40
-
-
5344233478
-
Pulmonary arterial hypertension
-
Farber HW, Loscalzo J. Pulmonary arterial hypertension. N Engl J Med 2004; 351: 1655-1665.
-
(2004)
N Engl J Med
, vol.351
, pp. 1655-1665
-
-
Farber, H.W.1
Loscalzo, J.2
|