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Volumn 1, Issue 6, 1996, Pages 453-460

A novel functional polymorphism within the promoter of the serotonin transporter gene: Possible role in susceptibility to affective disorders

Author keywords

Association; Bipolar disorder; Case control; Depression; Genetics; QTL; Serotonin transporter

Indexed keywords

CARRIER PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN; SEROTONIN; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, HUMAN;

EID: 0030320649     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (639)

References (29)
  • 2
    • 0027988327 scopus 로고
    • Sources of individual differences in depressive symptoms: Analysis of two samples of twins and their families
    • Kendler KS, Walters EE, Truett KR, Heath A, Neale MC, Martin NG, Eaves LJ. Sources of individual differences in depressive symptoms: analysis of two samples of twins and their families. Am J Psychiatry 1994; 151: 1605-1614.
    • (1994) Am J Psychiatry , vol.151 , pp. 1605-1614
    • Kendler, K.S.1    Walters, E.E.2    Truett, K.R.3    Heath, A.4    Neale, M.C.5    Martin, N.G.6    Eaves, L.J.7
  • 4
    • 0029000346 scopus 로고
    • Genetics of bipolar affective disorder: Time for another reinvention
    • Gelernter J. Genetics of bipolar affective disorder: time for another reinvention. Am J Hum Genet 1995; 56: 1262-1266.
    • (1995) Am J Hum Genet , vol.56 , pp. 1262-1266
    • Gelernter, J.1
  • 5
    • 0026725877 scopus 로고
    • Neurochemical alterations of serotonergic neuronal systems in depression
    • Risch SC, Nemeroff CB. Neurochemical alterations of serotonergic neuronal systems in depression. J Clin Psychiatry 1992; 53 (Suppl): 3-7.
    • (1992) J Clin Psychiatry , vol.53 , Issue.SUPPL. , pp. 3-7
    • Risch, S.C.1    Nemeroff, C.B.2
  • 6
    • 0028265462 scopus 로고
    • The role of serotonin in the pathophysiology of depression: Focus on the serotonin transporter
    • Owens MJ, Nemeroff CB. The role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clin Chem 1994; 40: 288-295.
    • (1994) Clin Chem , vol.40 , pp. 288-295
    • Owens, M.J.1    Nemeroff, C.B.2
  • 7
    • 0019801535 scopus 로고
    • Serotonin uptake in blood platelets of psychiatric patients
    • Meltzer H, Arora R, Baber R, Tricou B. Serotonin uptake in blood platelets of psychiatric patients. Arch Gen Psychiatry 1981; 38: 1322-1329.
    • (1981) Arch Gen Psychiatry , vol.38 , pp. 1322-1329
    • Meltzer, H.1    Arora, R.2    Baber, R.3    Tricou, B.4
  • 8
    • 0019310944 scopus 로고
    • Tritrated imipramine binding sites are decreased in platelets of untreated depressed patients
    • Briley MS, Langer SZ, Raiman R, Sechter D, Zarifian E. Tritrated imipramine binding sites are decreased in platelets of untreated depressed patients. Science 1980; 209; 303-305.
    • (1980) Science , vol.209 , pp. 303-305
    • Briley, M.S.1    Langer, S.Z.2    Raiman, R.3    Sechter, D.4    Zarifian, E.5
  • 9
    • 0027958881 scopus 로고
    • Imipramine binding in depression: A meta-analysis
    • Ellis PM, Salmond C. Imipramine binding in depression: a meta-analysis. Biol Psychiatry 1994; 36: 292-294.
    • (1994) Biol Psychiatry , vol.36 , pp. 292-294
    • Ellis, P.M.1    Salmond, C.2
  • 10
    • 0028829632 scopus 로고
    • Neurotransmitter reuptake mechanisms: Targets for drugs to study and treat psychiatric, neurological and neurodegenerative disorders
    • Lesch KP, Bengel D. Neurotransmitter reuptake mechanisms: targets for drugs to study and treat psychiatric, neurological and neurodegenerative disorders. CNS Drugs 1995; 4: 302-322.
    • (1995) CNS Drugs , vol.4 , pp. 302-322
    • Lesch, K.P.1    Bengel, D.2
  • 13
    • 0028332669 scopus 로고
    • Expression of a high-affinity serotonin transporter in human lymphocytes
    • Faraj BA, Olkowski ZL, Jackson RT. Expression of a high-affinity serotonin transporter in human lymphocytes. Int J Immunopharmacol 1994; 16: 561-567.
    • (1994) Int J Immunopharmacol , vol.16 , pp. 561-567
    • Faraj, B.A.1    Olkowski, Z.L.2    Jackson, R.T.3
  • 16
    • 0000130367 scopus 로고    scopus 로고
    • Association between bipolar disorder and the VNTR polymorphism in intron 2 of the human serotonin transporter (hSERT)
    • Craddock N, Rees M, Norton N, Feldman E, McGuffin P, Owen MJ. Association between bipolar disorder and the VNTR polymorphism in intron 2 of the human serotonin transporter (hSERT). Psychiatric Genetics 1996; 6: 147.
    • (1996) Psychiatric Genetics , vol.6 , pp. 147
    • Craddock, N.1    Rees, M.2    Norton, N.3    Feldman, E.4    McGuffin, P.5    Owen, M.J.6
  • 18
    • 1542490494 scopus 로고    scopus 로고
    • Serotonin transporter and affective disorder
    • Stöber G, Heils A, Lesch KP. Serotonin transporter and affective disorder. Lancet 1996; 347: 1341-1342.
    • (1996) Lancet , vol.347 , pp. 1341-1342
    • Stöber, G.1    Heils, A.2    Lesch, K.P.3
  • 20
    • 0021999432 scopus 로고
    • A chi-square test to distinguish allelic association from other causes of phenotypic association between two loci
    • Ott J. A chi-square test to distinguish allelic association from other causes of phenotypic association between two loci. Genet Epidemiol 1985; 2: 79-84.
    • (1985) Genet Epidemiol , vol.2 , pp. 79-84
    • Ott, J.1
  • 21
    • 0029873266 scopus 로고    scopus 로고
    • Association between schizophrenia and a T102C polymorphism in the 5-hydroxytryptamine type 2a-receptor gene
    • Williams J, Spurlock G, McGuffin P et al. Association between schizophrenia and a T102C polymorphism in the 5-hydroxytryptamine type 2a-receptor gene. Lancet 1996; 347: 1294-1296.
    • (1996) Lancet , vol.347 , pp. 1294-1296
    • Williams, J.1    Spurlock, G.2    McGuffin, P.3
  • 23
    • 0029981336 scopus 로고    scopus 로고
    • Genetic linkage study of bipolar disorder and the serotonin transporter
    • Kelsoe J, Remick R, Sadovnick D et al. Genetic linkage study of bipolar disorder and the serotonin transporter. Am J Med Genet 1996; 67: 215-217.
    • (1996) Am J Med Genet , vol.67 , pp. 215-217
    • Kelsoe, J.1    Remick, R.2    Sadovnick, D.3
  • 28
    • 13344260701 scopus 로고    scopus 로고
    • A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish
    • Ginns EJ, Ott J, Egeland JA et al. A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish. Nature Genet 1996; 12: 431-435.
    • (1996) Nature Genet , vol.12 , pp. 431-435
    • Ginns, E.J.1    Ott, J.2    Egeland, J.A.3
  • 29
    • 1542490497 scopus 로고    scopus 로고
    • Systematic: Screening for mutations in the coding region of the 5-HTT gene using PCR and DGGE
    • in press
    • Di Bella D, Catalano M, Balling U, Smeraldi E, Lesch KP. Systematic: screening for mutations in the coding region of the 5-HTT gene using PCR and DGGE. Am J Hum Genet 1996; (in press).
    • (1996) Am J Hum Genet
    • Di Bella, D.1    Catalano, M.2    Balling, U.3    Smeraldi, E.4    Lesch, K.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.