The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf +/- heterozygous null mice

Neuropharmacology

Volumn 62, Issue 1, 2012, Pages 391-397

  Lindholm, Jesse S O ^a   Autio, Henri ^a   Vesa, Liisa ^a   Antila, Hanna ^a   Lindemann, Lothar ^b   Hoener, Marius C ^b   Skolnick, Phil ^c   Rantamäki, Tomi ^a   Castrén, Eero ^a,d  

^a UNIVERSITY OF HELSINKI   (Finland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Brain derived neurotrophic factor; Depression; Glutamate; Ketamine; LY 4516461; TrkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; IMIPRAMINE; KETAMINE; N [2 [4 (4 CYANOPHENYL)PHENYL]PROPYL] 2 PROPANESULFONAMIDE;

ANIMAL EXPERIMENT; ANTIDEPRESSANT LIKE EFFECT; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; DRUG RESPONSE; FORCED SWIMMING TEST; HETEROZYGOSITY; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WILD TYPE;

ANALYSIS OF VARIANCE; ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; IMIPRAMINE; KETAMINE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REACTION TIME; RECEPTOR, TRKA; SULFONAMIDES; SWIMMING;

EID: 80054106740     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.08.015     Document Type: Conference Paper

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