메뉴 건너뛰기




Volumn 12, Issue 8, 2011, Pages 574-587

Mode of action of agomelatine: Synergy between melatonergic and 5-HT 2C receptors

Author keywords

Agomelatine; Circadian rhythms; Depression; Melatonergic receptor; Serotonergic receptor

Indexed keywords

4 AMINOBUTYRIC ACID; AGOMELATINE; ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUTAMIC ACID; MELATONIN; MELATONIN 1 RECEPTOR; MELATONIN 2 RECEPTOR; MESSENGER RNA; NORADRENALIN; S 22153; S 32006; SEROTONIN; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG;

EID: 82955188805     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.3109/15622975.2011.595823     Document Type: Review
Times cited : (112)

References (110)
  • 5
    • 33744919791 scopus 로고    scopus 로고
    • Agomelatine, a New Antidepressant, Induces Regional Changes in Hippocampal Neurogenesis
    • DOI 10.1016/j.biopsych.2005.11.025, PII S000632230600045X
    • Banasr M, Soumier A, Hery M, Mocaer E, Daszuta A. 2006. Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis. Biol Psychiatry 59:1087-1096. (Pubitemid 43849657)
    • (2006) Biological Psychiatry , vol.59 , Issue.11 , pp. 1087-1096
    • Banasr, M.1    Soumier, A.2    Hery, M.3    Mocaer, E.4    Daszuta, A.5
  • 6
    • 33751192681 scopus 로고    scopus 로고
    • Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model
    • Bertaina-Anglade V, Drieu La RC, Boyer PA, Mocaer E. 2006. Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model. Behav Pharmacol 17:703-713.
    • (2006) Behav Pharmacol , vol.17 , pp. 703-713
    • Bertaina-Anglade, V.1    La Drieu, R.C.2    Boyer, P.A.3    Mocaer, E.4
  • 7
    • 33745222513 scopus 로고    scopus 로고
    • The role of CREB in depression and antidepressant treatment
    • Blendy JA. 2006. The role of CREB in depression and antidepressant treatment. Biol Psychiatry 59(12):1144-1150.
    • (2006) Biol Psychiatry , vol.59 , Issue.12 , pp. 1144-1150
    • Blendy, J.A.1
  • 8
    • 16344378248 scopus 로고    scopus 로고
    • Chronic antidepressants reduce depolarization-evoked glutamate release and protein interactions favoring formation of SNARE complex in hippocampus
    • DOI 10.1523/JNEUROSCI.5033-04.2005
    • Bonanno G, Giambelli R, Raiteri L, Tiraboschi E, Zappettini S, Musazzi L, et al. 2005. Chronic antidepressants reduce depolarization-evoked glutamate release and protein interactions favoring formation of SNARE complex in hippocampus. J Neurosci 25:3270-3279. (Pubitemid 40471335)
    • (2005) Journal of Neuroscience , vol.25 , Issue.13 , pp. 3270-3279
    • Bonanno, G.1    Giambelli, R.2    Raiteri, L.3    Tiraboschi, E.4    Zappettini, S.5    Musazzi, L.6    Raiteri, M.7    Racagni, G.8    Popoli, M.9
  • 10
    • 2342459611 scopus 로고    scopus 로고
    • Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: Involvement of melatonin and serotonin receptors
    • Bourin M, Mocaer E, Porsolt R. 2004. Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: involvement of melatonin and serotonin receptors. J Psychiatry Neurosci 29:126-133. (Pubitemid 38570217)
    • (2004) Journal of Psychiatry and Neuroscience , vol.29 , Issue.2 , pp. 126-133
    • Bourin, M.1    Mocaer, E.2    Porsolt, R.3
  • 11
    • 24144483438 scopus 로고    scopus 로고
    • BDNF function in adult synaptic plasticity: The synaptic consolidation hypothesis
    • DOI 10.1016/j.pneurobio.2005.06.003, PII S0301008205000663
    • Bramham CR, Messaoudi E. 2005. BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis. Prog Neurobiol 76:99-125. (Pubitemid 41242884)
    • (2005) Progress in Neurobiology , vol.76 , Issue.2 , pp. 99-125
    • Bramham, C.R.1    Messaoudi, E.2
  • 12
    • 58149328474 scopus 로고    scopus 로고
    • The immediate early gene arc/arg3.1: Regulation, mechanisms, and function
    • Bramham CR, Worley PF, Moore MJ, Guzowski JF. 2008. The immediate early gene arc/arg3.1: regulation, mechanisms, and function. J Neurosci 28:11760-11767.
    • (2008) J Neurosci , vol.28 , pp. 11760-11767
    • Bramham, C.R.1    Worley, P.F.2    Moore, M.J.3    Guzowski, J.F.4
  • 14
    • 79955621481 scopus 로고    scopus 로고
    • Modulation of neuroplastic molecules in selected brain regions after chronic administration of the novel antidepressant agomelatine
    • Calabrese F, Molteni R, Gabriel C, Mocaer E, Racagni G, Riva MA. 2010. Modulation of neuroplastic molecules in selected brain regions after chronic administration of the novel antidepressant agomelatine. Psychopharmacology 215:267-275.
    • (2010) Psychopharmacology , vol.215 , pp. 267-275
    • Calabrese, F.1    Molteni, R.2    Gabriel, C.3    Mocaer, E.4    Racagni, G.5    Riva, M.A.6
  • 15
    • 79953743149 scopus 로고    scopus 로고
    • Melat onin and the metabolic syndrome: Physiopathologic and therapeutical implications
    • Cardinali DP, Cano P, Jiménez-Ortega V, Esquifino AI. 2011. Melat onin and the metabolic syndrome: physiopathologic and therapeutical implications. Neuroendocrinology 93:133-142.
    • (2011) Neuroendocrinology , vol.93 , pp. 133-142
    • Cardinali, D.P.1    Cano, P.2    Jiménez-Ortega, V.3    Esquifino, A.I.4
  • 17
    • 70449382547 scopus 로고    scopus 로고
    • The regulation of central and peripheral circadian clocks in humans
    • Cermakian N, Boivin DB. 2009. The regulation of central and peripheral circadian clocks in humans. Obes Rev 10 (Suppl 2):25-36.
    • (2009) Obes Rev , vol.10 , Issue.2 SUPPL. , pp. 25-36
    • Cermakian, N.1    Boivin, D.B.2
  • 18
    • 0242575035 scopus 로고    scopus 로고
    • 2C receptors in Wistar rats
    • DOI 10.1007/s00213-003-1465-3
    • Chagraoui A, Protais P, Filloux T, Mocaër E. 2003. Agomelatine (S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats. Psychopharmacology 170:17-22. (Pubitemid 37372474)
    • (2003) Psychopharmacology , vol.170 , Issue.1 , pp. 17-22
    • Chagraoui, A.1    Protais, P.2    Filloux, T.3    Mocaer, E.4
  • 19
    • 0034671184 scopus 로고    scopus 로고
    • Differential expression of plasticity-related genes in waking and sleep and their regulation by the noradrenergic system
    • Cirelli C, Tononi G. 2000. Differential expression of plasticityrelated genes in waking and sleep and their regulation by the noradrenergic system. J Neurosci 20:9187-9194. (Pubitemid 32042921)
    • (2000) Journal of Neuroscience , vol.20 , Issue.24 , pp. 9187-9194
    • Cirelli, C.1    Tononi, G.2
  • 20
    • 67749085893 scopus 로고    scopus 로고
    • The NGF saga: From animal models of psychosocial stress to stress-related psychopathology
    • Cirulli F, Alleva E. 2009. The NGF saga: From animal models of psychosocial stress to stress-related psychopathology. Front Neuroendocrinol 30:379-395.
    • (2009) Front Neuroendocrinol , vol.30 , pp. 379-395
    • Cirulli, F.1    Alleva, E.2
  • 21
    • 43249092028 scopus 로고    scopus 로고
    • Comparison of agomelatine and melatonin for effects in chronically stressed tree shrews, an animal model of depression
    • Corbach S, Schmelting B, Fuchs E, Mocaer E. 2007. Comparison of agomelatine and melatonin for effects in chronically stressed tree shrews, an animal model of depression. Eur Neuropsychopharmacol 17:S364-365.
    • (2007) Eur Neuropsychopharmacol , vol.17
    • Corbach, S.1    Schmelting, B.2    Fuchs, E.3    Mocaer, E.4
  • 23
    • 0030723483 scopus 로고    scopus 로고
    • Melatonin as a therapeutic agent in the treatment of sleep disturbance in depression
    • de Wries MW, Peeters FP. 1997. Melatonin as a therapeutic agent in the treatment of sleep disturbances in depression. J Nerv Ment Dis 185:201-202. (Pubitemid 27508673)
    • (1997) Journal of Nervous and Mental Disease , vol.185 , Issue.3 , pp. 201-202
    • Devries, M.W.1    Peeters, F.P.M.L.2
  • 24
    • 71649093603 scopus 로고    scopus 로고
    • Proteomic analysis reveals the role of synaptic vesicle cycling in sustaining the suprachiasmatic circadian clock
    • Deery MJ, Maywood ES, Chesham JE, Sladek M, Karp NA, Green EW, et al. 2009. Proteomic analysis reveals the role of synaptic vesicle cycling in sustaining the suprachiasmatic circadian clock. Curr Biol 19:2031-2036.
    • (2009) Curr Biol , vol.19 , pp. 2031-2036
    • Deery, M.J.1    Maywood, E.S.2    Chesham, J.E.3    Sladek, M.4    Karp, N.A.5    Green, E.W.6
  • 25
    • 48149111513 scopus 로고    scopus 로고
    • S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models
    • Dekeyne A, Mannoury la Cour C, Gobert A, Brocco M, Lejeune F, Serres F, et al. 2008. S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models. Psychopharmacology (Berlin) 199(4):549-568.
    • (2008) Psychopharmacology (Berlin) , vol.199 , Issue.4 , pp. 549-568
    • Dekeyne, A.1    Mannoury La Cour, C.2    Gobert, A.3    Brocco, M.4    Lejeune, F.5    Serres, F.6
  • 26
    • 0032940954 scopus 로고    scopus 로고
    • Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: A combined in vivo electrophysiological and microdialysis study
    • DOI 10.1016/S0306-4522(98)00655-1, PII S0306452298006551
    • Di Giovanni G, De Deurwaerdere P, Di Mascio M, Di Matteo V, Esposito E, Spampinato U. 1999. Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study. Neuroscience 91:587-597. (Pubitemid 29193268)
    • (1999) Neuroscience , vol.91 , Issue.2 , pp. 587-597
    • Di Giovanni, G.1    De Deurwaerdere, P.2    Di Mascio, M.3    Di Matteo, V.4    Esposito, E.5    Spampinato, U.6
  • 28
    • 0031870926 scopus 로고    scopus 로고
    • Melatonin for the treatment of sleep disturbances in major depressive disorder
    • Dolberg OT, Hirschmann S, Grunhaus L. 1998. Melatonin for the treatment of sleep disturbances in major depressive disorder. Am J Psychiatry 155:1119-1121. (Pubitemid 28357744)
    • (1998) American Journal of Psychiatry , vol.155 , Issue.8 , pp. 1119-1121
    • Dolberg, O.T.1    Hirschmann, S.2    Grunhaus, L.3
  • 29
    • 0032161469 scopus 로고    scopus 로고
    • 2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms
    • Dubocovich ML, Yun K, Al-Ghoul WM, Benloucif S, Masana MI. 1998. Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms. FASEB J 12:1211-1220. (Pubitemid 28418951)
    • (1998) FASEB Journal , vol.12 , Issue.12 , pp. 1211-1220
    • Dubocovich, M.L.1    Yun, K.2    Al-Ghoul, W.M.3    Benloucif, S.4    Masana, M.I.5
  • 30
    • 50249187869 scopus 로고    scopus 로고
    • Circadian oscillation of hippocampal MAPK activity and cAMP: Implications for memory persistence
    • Eckel-Mahan KL, Phan T, Han S, Wang H, Chan GC, Scheiner ZS, et al. 2008. Circadian oscillation of hippocampal MAPK activity and cAMP: implications for memory persistence. Nat Neurosci 11:1074-1082.
    • (2008) Nat Neurosci , vol.11 , pp. 1074-1082
    • Eckel-Mahan, K.L.1    Phan, T.2    Han, S.3    Wang, H.4    Chan, G.C.5    Scheiner, Z.S.6
  • 31
    • 33645402334 scopus 로고    scopus 로고
    • Melatonin receptors in humans: Biological role and clinical relevance
    • Ekmekcioglu C. 2006. Melatonin receptors in humans: biological role and clinical relevance. Biomed Pharmacother 60:97-108.
    • (2006) Biomed Pharmacother , vol.60 , pp. 97-108
    • Ekmekcioglu, C.1
  • 33
    • 0344246936 scopus 로고    scopus 로고
    • Retinal afferents to the dorsal raphe nucleus in rats and Mongolian gerbils
    • DOI 10.1002/(SICI)1096-9861(19991129)414:4<469::AID-CNE4>3.0.CO;2-P
    • Fite KV, Janusonis S, Foote W, Bengston L. 1999. Retinal afferents to the dorsal raphe nucleus in rats and Mongolian gerbils. J Comp Neurol 414:469-484. (Pubitemid 29506360)
    • (1999) Journal of Comparative Neurology , vol.414 , Issue.4 , pp. 469-484
    • Fite, K.V.1    Janusonis, S.2    Foote, W.3    Bengston, L.4
  • 34
    • 33847779219 scopus 로고    scopus 로고
    • Post-translational modifications regulate the ticking of the circadian clock
    • DOI 10.1038/nrm2106, PII NRM2106
    • Gallego M, Virshup DM. 2007. Post-translational modifications regulate the ticking of the circadian clock. Nat Rev Mol Cel Biol 8:139-148. (Pubitemid 46432533)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.2 , pp. 139-148
    • Gallego, M.1    Virshup, D.M.2
  • 35
    • 1642285042 scopus 로고    scopus 로고
    • 2C receptors to multiple actions of central serotonin systems
    • DOI 10.1016/j.ejphar.2004.01.036, PII S0014299904000457
    • Giorgetti M, Tecott LH. 2004. Contributions of 5-HT (2C) receptors to multiple actions of central serotonin systems. Eur J Pharmacol 488:1-9. (Pubitemid 38388517)
    • (2004) European Journal of Pharmacology , vol.488 , Issue.1-3 , pp. 1-9
    • Giorgetti, M.1    Tecott, L.H.2
  • 36
    • 0030061279 scopus 로고    scopus 로고
    • Melatonin and its new agonist S-20098 restore synchronized sleep fragmented by experimental trypanosome infection in the rat
    • DOI 10.1016/0361-9230(95)02032-2
    • Grassi-Zucconi G, Semprevivo M, Mocaer E, Kristensson K, Bentivoglio M. 1996. Melatonin and its new agonist S-20098 restore synchronized sleep fragmented by experimental trypanosome infection in the rat. Brain Res Bull 39:63-68. (Pubitemid 26020607)
    • (1996) Brain Research Bulletin , vol.39 , Issue.2 , pp. 63-68
    • Grassi-Zucconi, G.1    Semprevivo, M.2    Mocaer, E.3    Kristensson, K.4    Bentivoglio, M.5
  • 37
    • 34249883579 scopus 로고    scopus 로고
    • Challenging the omnipotence of the suprachiasmatic timekeeper: Are circadian oscillators present throughout the mammalian brain?
    • DOI 10.1111/j.1460-9568.2007.05581.x
    • Guilding C, Piggins HD. 2007. Challenging the omnipotence of the suprachiasmatic timekeeper: are circadian oscillators present throughout the mammalian brain? Eur J Neurosci 25:3195-3216. (Pubitemid 46872769)
    • (2007) European Journal of Neuroscience , vol.25 , Issue.11 , pp. 3195-3216
    • Guilding, C.1    Piggins, H.D.2
  • 38
    • 0034213297 scopus 로고    scopus 로고
    • Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory
    • Guzowski JF, Lyford GL, Stevenson GD, Houston FP, McGaugh JL, Worley PF, Barnes CA. 2000. Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J Neurosci 20:3993-4001. (Pubitemid 30365669)
    • (2000) Journal of Neuroscience , vol.20 , Issue.11 , pp. 3993-4001
    • Guzowski, J.F.1    Lyford, G.L.2    Stevenson, G.D.3    Houston, F.P.4    McGaugh, J.L.5    Worley, P.F.6    Barnes, C.A.7
  • 40
    • 82955209173 scopus 로고    scopus 로고
    • Phase relationships between core body temperature, melatonin, and sleep are associated with depression severity: Preliminary evidence for circadian misalignment in non-seasonal depression
    • Hasler B. P., Buysse DJ, Kupfer DJ, Germain A. 2009. Phase relationships between core body temperature, melatonin, and sleep are associated with depression severity: preliminary evidence for circadian misalignment in non-seasonal depression. Sleep 32:A345.
    • (2009) Sleep , vol.32
    • Hasler, B.P.1    Buysse, D.J.2    Kupfer, D.J.3    Germain, A.4
  • 41
    • 0042490526 scopus 로고    scopus 로고
    • A clockwork web: Circadian timing in brain and periphery, in health and disease
    • DOI 10.1038/nrn1177
    • Hastings MH, Reddy AB, Maywood ES. 2003. A clockwork web: circadian timing in brain and periphery, in health and disease. Nat Rev Neurosci 4:649-661. (Pubitemid 37280160)
    • (2003) Nature Reviews Neuroscience , vol.4 , Issue.8 , pp. 649-661
    • Hastings, M.H.1    Reddy, A.B.2    Maywood, E.S.3
  • 42
    • 0028814334 scopus 로고
    • Modulation of serotonin and corticosteroid receptor gene expression in the rat hippocampus with circadian rhythm and stress
    • Holmes MC, French KL, Seckl JR. 1995. Modulation of serotonin and corticosteroid receptor gene expression in the rat hippocampus with circadian rhythm and stress. Brain Res Mol Brain Res 28:186-192.
    • (1995) Brain Res Mol Brain Res , vol.28 , pp. 186-192
    • Holmes, M.C.1    French, K.L.2    Seckl, J.R.3
  • 43
    • 0030905665 scopus 로고    scopus 로고
    • Dysregulation of diurnal rhythms of serotonin 5-HT(2C) and corticosteroid receptor gene expression in the hippocampus with food restriction and glucocorticoids
    • Holmes MC, French KL, Seckl JR. 1997. Dysregulation of diurnal rhythms of serotonin 5-HT2C and corticosteroid receptor gene expression in the hippocampus with food restriction and glucocorticoids. J Neurosci 17:4056-4065. (Pubitemid 27220596)
    • (1997) Journal of Neuroscience , vol.17 , Issue.11 , pp. 4056-4065
    • Holmes, M.C.1    French, K.L.2    Seckl, J.R.3
  • 44
    • 49549108229 scopus 로고    scopus 로고
    • A phase advance of the light-dark cycle stimulates production of BDNF, but not of other neurotrophins, in the adult rat cerebral cortex: Association with the activation of CREB
    • Katoh-Semba R, Tsuzuki M, Miyazaki N, Matsuda M, Nakagawa C, Ichisaka S, et al. 2008. A phase advance of the light-dark cycle stimulates production of BDNF, but not of other neurotrophins, in the adult rat cerebral cortex: association with the activation of CREB. J Neurochem 106:2131-2142.
    • (2008) J Neurochem , vol.106 , pp. 2131-2142
    • Katoh-Semba, R.1    Tsuzuki, M.2    Miyazaki, N.3    Matsuda, M.4    Nakagawa, C.5    Ichisaka, S.6
  • 45
    • 77649107286 scopus 로고    scopus 로고
    • Efficacy of the novel antidepressant agomelatine on the circadian rest-activity cycle and depressive and anxiety symptoms in patients with major depressive disorder: A randomized, double-blind comparison with sertraline
    • Kasper S, Hajak G, Wulff K, Hoogendijk WJ, Montejo AL, Smeraldi E, et al. 2010. Efficacy of the novel antidepressant agomelatine on the circadian rest-activity cycle and depressive and anxiety symptoms in patients with major depressive disorder: A randomized, double-blind comparison with sertraline. J Clin Psychiatry 71:109-120.
    • (2010) J Clin Psychiatry , vol.71 , pp. 109-120
    • Kasper, S.1    Hajak, G.2    Wulff, K.3    Hoogendijk, W.J.4    Montejo, A.L.5    Smeraldi, E.6
  • 46
    • 0030581114 scopus 로고    scopus 로고
    • Is there a direct retina-raphe-suprachiasmatic nucleus pathway in the rat?
    • DOI 10.1016/0304-3940(96)12795-6
    • Kawano H, Decker K, Reuss S. 1996. Is there a direct retinaraphe- suprachiasmatic nucleus pathway in the rat? Neurosci Lett 212:143-146. (Pubitemid 26298561)
    • (1996) Neuroscience Letters , vol.212 , Issue.2 , pp. 143-146
    • Kawano, H.1    Decker, K.2    Reuss, S.3
  • 47
    • 0035815551 scopus 로고    scopus 로고
    • Serotonin, excitatory amino acids and the photic control of melatonin rhythms and SCN c-FOS in the rat
    • DOI 10.1016/S0006-8993(01)02091-1, PII S0006899301020911
    • Kennaway DJ, Moyer RW, Voultsios A, Varcoe TJ. 2001. Serotonin, excitatory amino acids and the photic control of melatonin rhythms and SCN c-FOS in the rat. Brain Res 897:36-43. (Pubitemid 32244350)
    • (2001) Brain Research , vol.897 , Issue.1-2 , pp. 36-43
    • Kennaway, D.J.1    Moyer, R.W.2    Voultsios, A.3    Varcoe, T.J.4
  • 48
    • 77952115305 scopus 로고    scopus 로고
    • Agomelatine in the treatment of major depressive disorder. Potential for clinical effectiveness
    • Kennedy SH, Rizvi SJ. 2010. Agomelatine in the treatment of major depressive disorder. Potential for clinical effectiveness. CNS Drugs 24:479-499.
    • (2010) CNS Drugs , vol.24 , pp. 479-499
    • Kennedy, S.H.1    Rizvi, S.J.2
  • 49
    • 0041663885 scopus 로고    scopus 로고
    • The circadian system and melatonin: Lessons from rats and mice
    • DOI 10.1081/CBI-120022415
    • Korf HW, Von GC, Stehle J. 2003. The circadian system and melatonin: lessons from rats and mice. Chronobiol Int 20:697-710. (Pubitemid 36927465)
    • (2003) Chronobiology International , vol.20 , Issue.4 , pp. 697-710
    • Korf, H.-W.1    Von Gall, C.2    Stehle, J.3
  • 50
    • 33646689322 scopus 로고    scopus 로고
    • Sleep disturbances and depression: A challenge for antidepressants
    • DOI 10.1097/01.yic.0000195658.91524.61, PII 0000485020060200100005
    • Lam RW. 2006. Sleep disturbances and depression: a challenge for antidepressants. Int Clin Psychopharmacol 21 (Suppl 1): S25-29. (Pubitemid 43740330)
    • (2006) International Clinical Psychopharmacology , vol.21 , Issue.SUPPL. 1
    • Lam, R.W.1
  • 51
    • 0035966317 scopus 로고    scopus 로고
    • Posttranslational mechanisms regulate the mammalian circadian clock
    • DOI 10.1016/S0092-8674(01)00610-9
    • Lee C, Etchegaray JP, Cagampang FR, Loudon AS, Reppert SM. 2001. Posttranslational mechanisms regulate the mammalian circadian clock. Cell 107:855-867. (Pubitemid 34084977)
    • (2001) Cell , vol.107 , Issue.7 , pp. 855-867
    • Lee, C.1    Etchegaray, J.-P.2    Cagampang, F.R.A.3    Loudon, A.S.I.4    Reppert, S.M.5
  • 52
    • 0026661007 scopus 로고
    • Melatonin shifts human circadian rhythms according to a phase-response curve
    • Lewy AJ, Ahmed S, Jackson JM, Sack RL. 1992. Melatonin shifts human circadian rhythms according to a phase-response curve. Chronobiol Int 9:380-392.
    • (1992) Chronobiol Int , vol.9 , pp. 380-392
    • Lewy, A.J.1    Ahmed, S.2    Jackson, J.M.3    Sack, R.L.4
  • 54
    • 77955175453 scopus 로고    scopus 로고
    • The novel antidepressant, agomelatine, blocks cerebral 5-HT2C receptors in vivo: A phMRI challenge study in rats
    • Linnik IV, McKie S, Stark JA, Luckman S, Seguin L, Mocaer E, et al. 2009. The novel antidepressant, agomelatine, blocks cerebral 5-HT2C receptors in vivo: a phMRI challenge study in rats. Eur Neuropsychopharmacol 19:S259.
    • (2009) Eur Neuropsychopharmacol , vol.19
    • Linnik, I.V.1    McKie, S.2    Stark, J.A.3    Luckman, S.4    Seguin, L.5    Mocaer, E.6
  • 55
    • 0036738228 scopus 로고    scopus 로고
    • Determination of the dose of agomelatine, a melatoninergic agonist and selective 5-HT (2C) antagonist, in the treatment of major depressive disorder: A placebo-controlled dose range study
    • Lôo H, Hale A, D'haenen H. 2002. Determination of the dose of agomelatine, a melatoninergic agonist and selective 5-HT (2C) antagonist, in the treatment of major depressive disorder: a placebo-controlled dose range study. Int Clin Psychopharmacol 17:239-247.
    • (2002) Int Clin Psychopharmacol , vol.17 , pp. 239-247
    • Lôo, H.1    Hale, A.2    D'haenen, H.3
  • 56
    • 4544362674 scopus 로고    scopus 로고
    • Mammalian circadian biology: Elucidating genome-wide levels of temporal organization
    • DOI 10.1146/annurev.genom.5.061903.175925
    • Lowrey PL, Takahashi JS. 2004. Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annu Rev Genomics Hum Genet 5:407-441. (Pubitemid 39362752)
    • (2004) Annual Review of Genomics and Human Genetics , vol.5 , pp. 407-441
    • Lowrey, P.L.1    Takahashi, J.S.2
  • 57
    • 60349112891 scopus 로고    scopus 로고
    • Circuit projection from suprachiasmatic nucleus to ventral tegmental area: A novel circadian output pathway
    • Luo AH, Aston-Jones G. 2009. Circuit projection from suprachiasmatic nucleus to ventral tegmental area: a novel circadian output pathway. Eur J Neurosci 29:748-760.
    • (2009) Eur J Neurosci , vol.29 , pp. 748-760
    • Luo, A.H.1    Aston-Jones, G.2
  • 58
    • 0028853459 scopus 로고
    • Arc, a growth factor and activityregulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites
    • Lyford GL, Yamagata K, Kaufmann WE, Barnes CA, Sanders LK, Copeland NG, et al. 1995. Arc, a growth factor and activityregulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites. Neuron 14:433-445.
    • (1995) Neuron , vol.14 , pp. 433-445
    • Lyford, G.L.1    Yamagata, K.2    Kaufmann, W.E.3    Barnes, C.A.4    Sanders, L.K.5    Copeland, N.G.6
  • 59
    • 0037717094 scopus 로고    scopus 로고
    • Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: Evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway
    • DOI 10.1016/S0304-3940(03)00306-9
    • Mantovani M, Pertile R, Calixto JB, Santos AR, Rodrigues AL. 2003. Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway. Neurosci Lett 343:1-4. (Pubitemid 36577198)
    • (2003) Neuroscience Letters , vol.343 , Issue.1 , pp. 1-4
    • Mantovani, M.1    Pertile, R.2    Calixto, J.B.3    Santos, A.R.S.4    Rodrigues, A.L.S.5
  • 60
    • 0030218832 scopus 로고    scopus 로고
    • Entrainment of circadian rhythms by S-20098, a melatonin agonist, is dose and plasma concentration dependent
    • DOI 10.1016/0091-3057(95)02221-X
    • Martinet L, Guardiola Lemaitre B, Mocaer E. 1996. Entrainment of circadian rhythms by S-20098, a melatonin agonist, is dose and plasma concentration dependent. Pharmacol Biochem Behav 54:713-718. (Pubitemid 26258654)
    • (1996) Pharmacology Biochemistry and Behavior , vol.54 , Issue.4 , pp. 713-718
    • Martinet, L.1    Guardiola-Lemaitre, B.2    Mocaer, E.3
  • 61
    • 34548336779 scopus 로고    scopus 로고
    • New insights into BDNF function in depression and anxiety
    • DOI 10.1038/nn1971, PII NN1971
    • Martinowich K, Manji H, Lu B. 2007. New insights into BDNF function in depression and anxiety. Nat Neurosci 10:1089-1093. (Pubitemid 47339961)
    • (2007) Nature Neuroscience , vol.10 , Issue.9 , pp. 1089-1093
    • Martinowich, K.1    Manji, H.2    Lu, B.3
  • 62
    • 0033621791 scopus 로고    scopus 로고
    • 1 melatonin receptor expression in the suprachiasmatic nucleus of the C3H/HeN mouse
    • Masana MI, Benloucif S, Dubocovich ML. 2000. Circadian rhythm of mt1 melatonin receptor expression in the suprachiasmatic nucleus of the C3H/HeN mouse. J Pineal Res 28:185-192. (Pubitemid 30162451)
    • (2000) Journal of Pineal Research , vol.28 , Issue.3 , pp. 185-192
    • Masana, M.I.1    Benloucif, S.2    Dubocovich, M.L.3
  • 63
    • 70349972978 scopus 로고    scopus 로고
    • Brain clocks: From the suprachiasmatic nuclei to a cerebral network
    • Mendoza J, Challet E. 2009. Brain clocks: from the suprachiasmatic nuclei to a cerebral network. Neuroscientist 15:477-488.
    • (2009) Neuroscientist , vol.15 , pp. 477-488
    • Mendoza, J.1    Challet, E.2
  • 64
    • 0034638488 scopus 로고    scopus 로고
    • Imipramine and phenelzine decrease glutamate overflow in the prefrontal cortex-a possible mechanism of neuroprotection in major depression?
    • Michael-Titus AT, Bains S, Jeetle J, Whelpton R. 2000. Imipramine and phenelzine decrease glutamate overflow in the prefrontal cortex-a possible mechanism of neuroprotection in major depression? Neuroscience 100:681-684.
    • (2000) Neuroscience , vol.100 , pp. 681-684
    • Michael-Titus, A.T.1    Bains, S.2    Jeetle, J.3    Whelpton, R.4
  • 65
    • 33645230435 scopus 로고    scopus 로고
    • Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: Focus on novel therapeutic strategies
    • Millan MJ. 2005. Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies. Therapie 60:441-460.
    • (2005) Therapie , vol.60 , pp. 441-460
    • Millan, M.J.1
  • 67
    • 13644250791 scopus 로고    scopus 로고
    • Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: Role of 5HT (2C) receptor blockade
    • Millan MJ, Brocco M, Gobert A, Dekeyne A. 2005. Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5HT (2C) receptor blockade. Psychopharmacology (Berlin) 177:448-458.
    • (2005) Psychopharmacology (Berlin) , vol.177 , pp. 448-458
    • Millan, M.J.1    Brocco, M.2    Gobert, A.3    Dekeyne, A.4
  • 68
    • 77649107717 scopus 로고    scopus 로고
    • Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration
    • Molteni R, Calabrese F, Pisoni S, Gabriel C, Mocaer E, Racagni G, et al. 2010. Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration. World J Biol Psychiatry 11:148-153.
    • (2010) World J Biol Psychiatry , vol.11 , pp. 148-153
    • Molteni, R.1    Calabrese, F.2    Pisoni, S.3    Gabriel, C.4    Mocaer, E.5    Racagni, G.6
  • 69
    • 0033609683 scopus 로고    scopus 로고
    • Immunohistochemical localization of serotonin receptors in the rat suprachiasmatic nucleus
    • Moyer RW, Kennaway DJ. 1999. Immunohistochemical localization of serotonin receptors in the rat suprachiasmatic nucleus. Neurosci Lett 271:147-150.
    • (1999) Neurosci Lett , vol.271 , pp. 147-150
    • Moyer, R.W.1    Kennaway, D.J.2
  • 70
    • 84943014098 scopus 로고    scopus 로고
    • Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats
    • Berlin, April 19 2011, Epub ahead of print
    • Morley-Fletcher S, Mairesse J, Soumier A, Banasr M, Fagioli F, Gabriel C, et al. 2011. Chronic agomelatine treatment corrects behavioral, cellular, and biochemical abnormalities induced by prenatal stress in rats. Psychopharmacology (Berlin). 2011 (April 19 [Epub ahead of print]).
    • (2011) Psychopharmacology
    • Morley-Fletcher, S.1    Mairesse, J.2    Soumier, A.3    Banasr, M.4    Fagioli, F.5    Gabriel, C.6
  • 71
    • 77649124734 scopus 로고    scopus 로고
    • Acute stress increases depolarizationevoked glutamate release in the rat prefrontal/frontal cortex: The dampening action of antidepressants
    • doi:10.1371/journal.pone.0008566
    • Musazzi L, Milanese M, Farisello P, Zappettini S, Tardito D, Barbiero VS, et al. 2010. Acute stress increases depolarizationevoked glutamate release in the rat prefrontal/frontal cortex: the dampening action of antidepressants. PloS ONE 5(1):e8566 (doi:10.1371/journal.pone.0008566).
    • (2010) PloS ONE , vol.5 , Issue.1
    • Musazzi, L.1    Milanese, M.2    Farisello, P.3    Zappettini, S.4    Tardito, D.5    Barbiero, V.S.6
  • 73
    • 77957144923 scopus 로고    scopus 로고
    • Behavioural and neuroplastic effects of the newgeneration antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice
    • Paizanis E, Renoir T, Lelievre V, Saurini F, Melfort M, Gabriel C, et al. 2010. Behavioural and neuroplastic effects of the newgeneration antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice. Int J Neuropsychopharmacol 13:759-774.
    • (2010) Int J Neuropsychopharmacol , vol.13 , pp. 759-774
    • Paizanis, E.1    Renoir, T.2    Lelievre, V.3    Saurini, F.4    Melfort, M.5    Gabriel, C.6
  • 74
    • 0029975740 scopus 로고    scopus 로고
    • Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT(2C) receptor
    • DOI 10.1007/BF02246453
    • Palvimaki EP, Roth BL, Majasuo H, Laakso A, Kuoppamaki M, Syvalahti E, et al. 1996. Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor. Psychopharmacology (Berlin) 126:234-240. (Pubitemid 26252760)
    • (1996) Psychopharmacology , vol.126 , Issue.3 , pp. 234-240
    • Palvimaki, E.-P.1    Roth, B.L.2    Majasuo, H.3    Laakso, A.4    Kuoppamaki, M.5    Syvalahti, E.6    Hietala, J.7
  • 75
    • 67650594924 scopus 로고    scopus 로고
    • Bidirectional communication between sleep and circadian rhythms and its implications for depression: Lessons from agomelatine
    • Pandi-Perumal SR, Moscovitch A, Srinivasan V, Spence DW, Cardinali DP, Brown GM. 2009. Bidirectional communication between sleep and circadian rhythms and its implications for depression: lessons from agomelatine. Prog Neurobiol 88:264-271.
    • (2009) Prog Neurobiol , vol.88 , pp. 264-271
    • Pandi-Perumal, S.R.1    Moscovitch, A.2    Srinivasan, V.3    Spence, D.W.4    Cardinali, D.P.5    Brown, G.M.6
  • 76
    • 0038050606 scopus 로고    scopus 로고
    • Effect of agomelatine in the chronic mild stress model of depression in the rat
    • Papp M, Gruca P, Boyer PA, Mocaer E. 2003. Effect of agomelatine in the chronic mild stress model of depression in the rat. Neuropsychopharmacology 28:694-703.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 694-703
    • Papp, M.1    Gruca, P.2    Boyer, P.A.3    Mocaer, E.4
  • 78
    • 77950950826 scopus 로고    scopus 로고
    • The pharmacological properties of antidepressants
    • Racagni G, Popoli M. 2010. The pharmacological properties of antidepressants. Int Clin Psychopharmacology 25:117-131.
    • (2010) Int Clin Psychopharmacology , vol.25 , pp. 117-131
    • Racagni, G.1    Popoli, M.2
  • 79
    • 0031989198 scopus 로고    scopus 로고
    • Entrainment of Rat Circadian Rhythms by the Melatonin Agonist S-20098 Requires Intact Suprachiasmatic Nuclei but Not the Pineal
    • Redman JR, Francis AJ. 1998. Entrainment of rat circadian rhythms by the melatonin agonist S-20098 requires intact suprachiasmatic nuclei but not the pineal. J Biol Rhythms 13:39-51. (Pubitemid 128478945)
    • (1998) Journal of Biological Rhythms , vol.13 , Issue.1 , pp. 39-51
    • Redman, J.R.1    Francis, A.J.P.2
  • 80
    • 0028916266 scopus 로고
    • Dose dependent effects of S-20098, a melatonin agonist, on direction of re-entrainment of rat circadian activity rhythms
    • Redman JR, Guardiola-Lemaitre B, Brown M, Delagrange P, Armstrong SM. 1995. Dose dependent effects of S-20098, a melatonin agonist, on direction of re-entrainment of rat circadian activity rhythms. Psychopharmacology (Berlin) 118:385-390.
    • (1995) Psychopharmacology (Berlin) , vol.118 , pp. 385-390
    • Redman, J.R.1    Guardiola-Lemaitre, B.2    Brown, M.3    Delagrange, P.4    Armstrong, S.M.5
  • 81
    • 0035919618 scopus 로고    scopus 로고
    • NPAS2: An analog of clock operative in the mammalian forebrain
    • DOI 10.1126/science.1060699
    • Reick M, Garcia JA, Dudley C, McKnight SL. 2001. NPAS2: an analog of clock operative in the mammalian forebrain. Science 293:506-509. (Pubitemid 32679079)
    • (2001) Science , vol.293 , Issue.5529 , pp. 506-509
    • Reick, M.1    Garcia, J.A.2    Dudley, C.3    McKnight, S.L.4
  • 82
    • 0037194790 scopus 로고    scopus 로고
    • Coordination of circadian timing in mammals
    • DOI 10.1038/nature00965
    • Reppert SM, Weaver DR. 2002. Coordination of circadian timing in mammals. Nature 418:935-941. (Pubitemid 34976023)
    • (2002) Nature , vol.418 , Issue.6901 , pp. 935-941
    • Reppert, S.M.1    Weaver, D.R.2
  • 83
    • 42949123365 scopus 로고    scopus 로고
    • Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders
    • DOI 10.1038/nrd2462, PII NRD2462
    • Sanacora G, Zarate CA, Krystal JH, Manji HK. 2008. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Discov 7:426-437. (Pubitemid 351619114)
    • (2008) Nature Reviews Drug Discovery , vol.7 , Issue.5 , pp. 426-437
    • Sanacora, G.1    Zarate, C.A.2    Krystal, J.H.3    Manji, H.K.4
  • 84
    • 0034642063 scopus 로고    scopus 로고
    • Entrainment of free-running circadian rhythms by melatonin in blind people
    • Sack RL, Brandes RW, Kendall AR, Lewy AJ. 2000. Entrainment of free-running circadian rhythms by melatonin in blind people. New Engl J Med 343:1070-1077.
    • (2000) New Engl J Med , vol.343 , pp. 1070-1077
    • Sack, R.L.1    Brandes, R.W.2    Kendall, A.R.3    Lewy, A.J.4
  • 85
    • 0028120831 scopus 로고
    • A direct retinal projection to the dorsal raphe nucleus in the rat
    • Shen H, Semba K. 1994. A direct retinal projection to the dorsal raphe nucleus in the rat. Brain Res 635:159-168. (Pubitemid 24031400)
    • (1994) Brain Research , vol.635 , Issue.1-2 , pp. 159-168
    • Shen, H.1    Semba, K.2
  • 86
    • 0023676793 scopus 로고
    • Twenty-four-hour profiles of body temperature and plasma TSH in bipolar patients during depression and during remission and in normal control subjects
    • Souetre E, Salvati E, Wehr TA, Sack DA, Krebs B, Darcourt G. 1988. Twenty-four-hour profiles of body temperature and plasma TSH in bipolar patients during depression and during remission and in normal control subjects. Am J Psychiatry 145:1133-1137.
    • (1988) Am J Psychiatry , vol.145 , pp. 1133-1137
    • Souetre, E.1    Salvati, E.2    Wehr, T.A.3    Sack, D.A.4    Krebs, B.5    Darcourt, G.6
  • 87
    • 0024409434 scopus 로고
    • Circadian rhythms in depression and recovery: Evidence for blunted amplitude as the main chronobiological abnormality
    • DOI 10.1016/0165-1781(89)90207-2
    • Souetre E, Salvati E, Belugou JL, Pringuey D, Candito M, Krebs B, et al. 1989. Circadian rhythms in depression and recovery: evidence for blunted amplitude as the main chronobiological abnormality. Psychiatry Res 28:263-278. (Pubitemid 19165767)
    • (1989) Psychiatry Research , vol.28 , Issue.3 , pp. 263-278
    • Souetre, E.1    Salvati, E.2    Belugou, J.-L.3    Pringuey, D.4    Candito, M.5    Krebs, B.6    Ardisson, J.-L.7    Darcourt, G.8
  • 88
    • 70349142643 scopus 로고    scopus 로고
    • Mechanisms contributing to the phase-dependent regulation of neurogenesis by the novel antidepressant, agomelatine, in the adult rat hippocampus
    • Soumier A, Banasr M, Lortet S, Masmejean F, Bernard N, Kerkerian Le GL, et al. 2009. Mechanisms contributing to the phase-dependent regulation of neurogenesis by the novel antidepressant, agomelatine, in the adult rat hippocampus. Neuropsychopharmacology 34:2390-2403.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2390-2403
    • Soumier, A.1    Banasr, M.2    Lortet, S.3    Masmejean, F.4    Bernard, N.5    Kerkeran Le, G.L.6
  • 89
    • 0026150398 scopus 로고
    • Psychotropic effects of ritanserin, a selective S2 antagonist: An open study
    • Strauss WH, Klieser E. 1991. Psychotropic effects of ritanserin, a selective S2 antagonist: an open study. Eur Neuropsychopharmacol 1:101-105.
    • (1991) Eur Neuropsychopharmacol , vol.1 , pp. 101-105
    • Strauss, W.H.1    Klieser, E.2
  • 90
    • 52149109334 scopus 로고    scopus 로고
    • The genetics of mammalian circadian order and disorder: Implications for physiology and disease
    • Takahashi JS, Hong H, Ko CH, McDearmon EL. 2008. The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nat Rev Gen 9:764-775.
    • (2008) Nat Rev Gen , vol.9 , pp. 764-775
    • Takahashi, J.S.1    Hong, H.2    Ko, C.H.3    McDearmon, E.L.4
  • 91
    • 33644596087 scopus 로고    scopus 로고
    • Signaling pathways regulating gene expression, neuroplasticity and neurotrophic mechanisms in the action of antidepressants. A critical overview
    • Tardito D, Perez J, Tiraboschi E, Musazzi L, Racagni G, Popoli M. 2006. Signaling pathways regulating gene expression, neuroplasticity and neurotrophic mechanisms in the action of antidepressants. A critical overview. Pharmacol Rev 58:115-134.
    • (2006) Pharmacol Rev , vol.58 , pp. 115-134
    • Tardito, D.1    Perez, J.2    Tiraboschi, E.3    Musazzi, L.4    Racagni, G.5    Popoli, M.6
  • 93
    • 79953817256 scopus 로고    scopus 로고
    • Time in the brain: Rhythms of intercellular and intracellular processes
    • Tardito D, Racagni G, Popoli M. 2010a. Time in the brain: rhythms of intercellular and intracellular processes. Medicographia 32:152-158.
    • (2010) Medicographia , vol.32 , pp. 152-158
    • Tardito, D.1    Racagni, G.2    Popoli, M.3
  • 95
    • 43049093681 scopus 로고    scopus 로고
    • Repeated administration of imipramine attenuates glutamatergic transmission in rat frontal cortex
    • Tokarski K, Bobula B, Wabno J, Hess G. 2008. Repeated administration of imipramine attenuates glutamatergic transmission in rat frontal cortex. Neuroscience 153:789-795.
    • (2008) Neuroscience , vol.153 , pp. 789-795
    • Tokarski, K.1    Bobula, B.2    Wabno, J.3    Hess, G.4
  • 97
    • 33750512959 scopus 로고    scopus 로고
    • Arc/Arg3.1: Linking Gene Expression to Synaptic Plasticity and Memory
    • DOI 10.1016/j.neuron.2006.10.016, PII S0896627306008154
    • Tzingounis AV, Nicoll RA. 2006. Arc/Arg3.1: linking gene expression to synaptic plasticity and memory. Neuron 52:403-407. (Pubitemid 44667439)
    • (2006) Neuron , vol.52 , Issue.3 , pp. 403-407
    • Tzingounis, A.V.1    Nicoll, R.A.2
  • 98
    • 0022731539 scopus 로고
    • Depression: A disorder of timekeeping?
    • Van Reeth, Turek F W. 1986. Depression: a disorder of timekeeping? Perspect Biol Med 29:510-519.
    • (1986) Perspect Biol Med , vol.29 , pp. 510-519
    • Van Reeth1    Turek, F.W.2
  • 100
    • 0030850846 scopus 로고    scopus 로고
    • Comparative effects of a melatonin agonist on the circadian system in mice and Syrian hamsters
    • DOI 10.1016/S0006-8993(97)00382-X, PII S000689939700382X
    • Van Reeth O, Olivares E, Zhang Y, Zee PC, Mocaer E, Defrance R, et al. 1997. Comparative effects of a melatonin agonist on the circadian system in mice and Syrian hamsters. Brain Res 762 (1-2): 185-194. (Pubitemid 27315948)
    • (1997) Brain Research , vol.762 , Issue.1-2 , pp. 185-194
    • Van Reeth, O.1    Olivares, E.2    Zhang, Y.3    Zee, P.C.4    Mocaer, E.5    Defrance, R.6    Turek, F.W.7
  • 102
    • 3042571673 scopus 로고    scopus 로고
    • Serotonin receptor ligands and the treatment of obesity
    • Vickers SP, Dourish CT. 2004. Serotonin receptor ligands and the treatment of obesity. Curr Opin Investig Drugs 5:377-388.
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 377-388
    • Vickers, S.P.1    Dourish, C.T.2
  • 103
    • 76649086554 scopus 로고    scopus 로고
    • Expression of the circadian clock gene Period2 in the hippocampus: Possible implications for synaptic plasticity and learned behaviour
    • doi:10.1042/AN20090020
    • Wang LM-C, Dragich JM, Kudo T, Odom IH, Welsh DK, O'Dell TJ, et al. 2009. Expression of the circadian clock gene Period2 in the hippocampus: possible implications for synaptic plasticity and learned behaviour. ASN Neuro 1(3): art:e00012 (doi:10.1042/AN20090020).
    • (2009) ASN Neuro , vol.1 , Issue.3
    • Wang, L.M.-C.1    Dragich, J.M.2    Kudo, T.3    Odom, I.H.4    Welsh, D.K.5    O'Dell, T.J.6
  • 104
    • 0032044191 scopus 로고    scopus 로고
    • The Suprachiasmatic Nucleus: A 25-Year Retrospective
    • Weaver DR. 1998. The suprachiasmatic nucleus: a 25-year retrospective. J Biol Rhythms 13:100-112. (Pubitemid 128478927)
    • (1998) Journal of Biological Rhythms , vol.13 , Issue.2 , pp. 100-112
    • Weaver, D.R.1
  • 105
    • 0024378185 scopus 로고
    • Localization and characterization of melatonin receptors in rodent brain by in vitro autoradiography
    • Weaver DR, Rivkees SA, Reppert SM. 1989. Localization and characterization of melatonin receptors in rodent brain by in vitro autoradiography. J Neurosci 9:2581-2590. (Pubitemid 19193588)
    • (1989) Journal of Neuroscience , vol.9 , Issue.7 , pp. 2581-2590
    • Weaver, D.R.1    Rivkees, S.A.2    Reppert, S.M.3
  • 106
    • 31744442798 scopus 로고    scopus 로고
    • Melatonin receptor (MT1) knockout mice display depression-like behaviors and deficits in sensorimotor gating
    • DOI 10.1016/j.brainresbull.2005.09.016, PII S036192300500417X
    • Weil ZM, Hotchkiss AK, Gatien ML, Pieke-Dahl S, Nelson RJ. 2006. Melatonin receptor (MT1) knockout mice display depression-like behaviors and deficits in sensorimotor gating. Brain Res Bull 68(6):425-429. (Pubitemid 43177577)
    • (2006) Brain Research Bulletin , vol.68 , Issue.6 , pp. 425-429
    • Weil, Z.M.1    Hotchkiss, A.K.2    Gatien, M.L.3    Pieke-Dahl, S.4    Nelson, R.J.5
  • 107
    • 33646682125 scopus 로고    scopus 로고
    • Biological rhythm disturbances in mood disorders
    • Wirz-Justice A. 2006. Biological rhythm disturbances in mood disorders. Int Clin Psychopharmacol 21 (Suppl 1): S11-15.
    • (2006) Int Clin Psychopharmacol , vol.21 , Issue.1 SUPPL.
    • Wirz-Justice, A.1
  • 108
    • 0034465880 scopus 로고    scopus 로고
    • Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat
    • DOI 10.1210/en.141.2.487
    • Wolden-Hanson T, Mitton DR, McCants RL, Yellon SM, Wilkinson CW, Matsumoto AM, et al. 2000. Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology 141:487-497. (Pubitemid 32250470)
    • (2000) Endocrinology , vol.141 , Issue.2 , pp. 487-497
    • Wolden-Hanson, T.1    Mitton, D.R.2    McCants, R.L.3    Yellon, S.M.4    Wilkinson, C.W.5    Matsumoto, A.M.6    Rasmussen, D.D.7
  • 109
    • 0036523102 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: Requirement for ERK activation coupled to CREB and upregulation of Arc synthesis
    • Ying SW, Futter M, Rosenblum K, Webber MJ, Hunt SP, Bliss TV, Bramham CR. 2002. Brain-derived neurotrophic factor induces long-term potentiation in intact adult hip pocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. J Neurosci 22:1532-1540. (Pubitemid 35386272)
    • (2002) Journal of Neuroscience , vol.22 , Issue.5 , pp. 1532-1540
    • Ying, S.-W.1    Futter, M.2    Rosenblum, K.3    Webber, M.J.4    Hunt, S.P.5    Bliss, T.V.P.6    Bramham, C.R.7
  • 110
    • 77949381494 scopus 로고    scopus 로고
    • GSK-3 β inhibits presynaptic vesicle exocytosis by phosphorylating P/Q-type calcium channel and interrupting SNARE complex formation
    • Zhu L-Q, Liu D, Hu J, Cheng J, Wang S-H, Wang Q, et al. 2010. GSK-3 β inhibits presynaptic vesicle exocytosis by phosphorylating P/Q-type calcium channel and interrupting SNARE complex formation. J Neurosci 30:3624-3633.
    • (2010) J Neurosci , vol.30 , pp. 3624-3633
    • Zhu, L.-Q.1    Liu, D.2    Hu, J.3    Cheng, J.4    Wang, S.-H.5    Wang, Q.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.