A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders

Neuroscience

Volumn 152, Issue 3, 2008, Pages 573-584

  Olivier, J D A ^a   Van Der Hart, M G C ^c   Van Swelm, R P L ^a   Dederen, P J ^a   Homberg, J R ^a,d   Cremers, T ^c   Deen, P M T ^a   Cuppen, E ^d   Cools, A R ^a   Ellenbroek, B A ^a,b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Evotec ^*  (Germany)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d HUBRECHT INSTITUTE   (Netherlands)

Author keywords

5 HT transporter; anxiety; depression; knockout rat; sex

Indexed keywords

CITALOPRAM; ETHYLNITROSOUREA; SEROTONIN TRANSPORTER;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; DEPRESSION; DORSAL RAPHE NUCLEUS; DRUG MECHANISM; FEMALE; FORCED SWIMMING TEST; GENE INACTIVATION; IMMUNOHISTOCHEMISTRY; MALE; MAZE TEST; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; SUGAR INTAKE; WILD TYPE;

ANIMALS; ANXIETY DISORDERS; APPETITE REGULATION; BRAIN; BRAIN CHEMISTRY; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EXPLORATORY BEHAVIOR; EXTRACELLULAR FLUID; FEMALE; MALE; MAZE LEARNING; MICRODIALYSIS; RAPHE NUCLEI; RATS; RATS, MUTANT STRAINS; REACTION TIME; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; SEX CHARACTERISTICS; SYNAPTIC TRANSMISSION;

EID: 40949084721     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2007.12.032     Document Type: Article

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