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Volumn 53, Issue , 2013, Pages 59-87

Epigenetic mechanisms of depression and antidepressant action

Author keywords

DNA methylation; early life stress; histone modification; limbic brain; noncoding RNA; transgenerational

Indexed keywords

ANTIDEPRESSANT AGENT; HISTONE DEACETYLASE INHIBITOR; IMIPRAMINE; UNTRANSLATED RNA;

EID: 84872241553     PISSN: 03621642     EISSN: 15454304     Source Type: Book Series    
DOI: 10.1146/annurev-pharmtox-010611-134540     Document Type: Review
Times cited : (226)

References (211)
  • 2
    • 69449108280 scopus 로고    scopus 로고
    • Stress and disorders of the stress system
    • Chrousos GP. 2009. Stress and disorders of the stress system. Nat. Rev. Endocrinol. 5:374-81
    • (2009) Nat. Rev. Endocrinol , vol.5 , pp. 374-381
    • Chrousos, G.P.1
  • 3
    • 72049085534 scopus 로고    scopus 로고
    • The neurocircuitry of fear, stress, and anxiety disorders
    • Shin LM, Liberzon I. 2009. The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology 35:169-91
    • (2009) Neuropsychopharmacology , vol.35 , pp. 169-191
    • Shin, L.M.1    Liberzon, I.2
  • 4
    • 40849133755 scopus 로고    scopus 로고
    • Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators
    • McEwen BS. 2008. Central effects of stress hormones in health and disease: understanding the protective and damaging effects of stress and stress mediators. Eur. J. Pharmacol. 583:174-85
    • (2008) Eur. J. Pharmacol , vol.583 , pp. 174-185
    • McEwen, B.S.1
  • 5
    • 77956771723 scopus 로고    scopus 로고
    • The concept of stress and its relevance for animal behavior
    • von Holst D. 1998. The concept of stress and its relevance for animal behavior. Adv. Study Behav. 27:1-131
    • (1998) Adv. Study Behav , vol.27 , pp. 1-131
    • Von Holst, D.1
  • 6
    • 77955951477 scopus 로고    scopus 로고
    • Socioeconomic status and the brain: Mechanistic insights from human and animal research
    • Hackman DA, Farah MJ, Meaney MJ. 2010. Socioeconomic status and the brain: mechanistic insights from human and animal research. Nat. Rev. Neurosci. 11:651-59
    • (2010) Nat. Rev. Neurosci , vol.11 , pp. 651-659
    • Hackman, D.A.1    Farah, M.J.2    Meaney, M.J.3
  • 7
    • 66449097460 scopus 로고    scopus 로고
    • Neuroscience, molecular biology, and the childhood roots of health disparities: Building a new framework for health promotion and disease prevention
    • Shonkoff JP, Boyce WT, McEwen BS. 2009. Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention. JAMA 301:2252-59
    • (2009) JAMA , vol.301 , pp. 2252-2259
    • Shonkoff, J.P.1    Boyce, W.T.2    McEwen, B.S.3
  • 8
    • 0032535185 scopus 로고    scopus 로고
    • Predicting the development of posttraumatic stress disorder from the acute response to a traumatic event
    • Yehuda R, McFarlane AC, Shalev AY. 1998. Predicting the development of posttraumatic stress disorder from the acute response to a traumatic event. Biol. Psychiatry 44:1305-13
    • (1998) Biol. Psychiatry , vol.44 , pp. 1305-1313
    • Yehuda, R.1    McFarlane, A.C.2    Shalev, A.Y.3
  • 9
    • 35348832393 scopus 로고    scopus 로고
    • Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions
    • KrishnanV,Han MH,Graham DL, Berton O, Renthal W, et al. 2007. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 131:391-404
    • (2007) Cell , vol.131 , pp. 391-404
    • Krishnan, V.1    Han, M.H.2    Graham, D.L.3    Berton, O.4    Renthal, W.5
  • 10
    • 66349093383 scopus 로고    scopus 로고
    • Psychobiology and molecular genetics of resilience
    • Feder A, Nestler EJ, Charney DS. 2009. Psychobiology and molecular genetics of resilience. Nat. Rev. Neurosci. 10:446-57
    • (2009) Nat. Rev. Neurosci , vol.10 , pp. 446-457
    • Feder, A.1    Nestler, E.J.2    Charney, D.S.3
  • 11
    • 77954329952 scopus 로고    scopus 로고
    • Animal models of early life stress: Implications for understanding resilience
    • Lyons DM, Parker KJ, Schatzberg AF. 2010. Animal models of early life stress: implications for understanding resilience. Dev. Psychobiol. 52:616-24
    • (2010) Dev. Psychobiol , vol.52 , pp. 616-624
    • Lyons, D.M.1    Parker, K.J.2    Schatzberg, A.F.3
  • 12
    • 79958039842 scopus 로고    scopus 로고
    • Genes, environment, and individual differences in responding to treatment for depression
    • Uher R. 2011. Genes, environment, and individual differences in responding to treatment for depression. Harv. Rev. Psychiatry 19:109-24
    • (2011) Harv. Rev. Psychiatry , vol.19 , pp. 109-124
    • Uher, R.1
  • 13
    • 84883157058 scopus 로고    scopus 로고
    • The road not taken: Life experiences in monozygotic twin pairs discordant for major depression
    • In press doi: 10.1038/mp.2012.55
    • Kendler KS, Halberstadt LJ. 2012. The road not taken: life experiences in monozygotic twin pairs discordant for major depression. Mol. Psychiatry. In press, doi: 10.1038/mp.2012.55
    • (2012) Mol. Psychiatry
    • Kendler, K.S.1    Halberstadt, L.J.2
  • 14
    • 0030032338 scopus 로고    scopus 로고
    • Initiation and adaptation: A paradigm for understanding psychotropic drug action
    • Hyman SE, Nestler EJ. 1996. Initiation and adaptation: a paradigm for understanding psychotropic drug action. Am. J. Psychiatry 153:151-62
    • (1996) Am. J. Psychiatry , vol.153 , pp. 151-162
    • Hyman, S.E.1    Nestler, E.J.2
  • 15
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman RS, Monteggia LM. 2006. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry 59:1116-27
    • (2006) Biol. Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 16
    • 32444451651 scopus 로고    scopus 로고
    • Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
    • Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, et al. 2006. Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 311:864-68
    • (2006) Science , vol.311 , pp. 864-868
    • Berton, O.1    McClung, C.A.2    Dileone, R.J.3    Krishnan, V.4    Renthal, W.5
  • 17
    • 40849094032 scopus 로고    scopus 로고
    • Generation and behavioral characterization of β-catenin forebrain-specific conditional knock-out mice
    • Gould TD, O'Donnell KC, PicchiniAM,Dow ER, Chen G, Manji HK. 2008. Generation and behavioral characterization of β-catenin forebrain-specific conditional knock-out mice. Behav. Brain Res. 189:117-25
    • (2008) Behav. Brain Res , vol.189 , pp. 117-125
    • Gould, T.D.1    O'Donnell, K.C.2    Picchiniamdow, E.R.3    Chen, G.4    Manji, H.K.5
  • 19
    • 77956178815 scopus 로고    scopus 로고
    • Wnt2 expression and signaling is increased by different classes of antidepressant treatments
    • Okamoto H, Voleti B, Banasr M, Sarhan M, Duric V, et al. 2010. Wnt2 expression and signaling is increased by different classes of antidepressant treatments. Biol. Psychiatry 68:521-27
    • (2010) Biol. Psychiatry , vol.68 , pp. 521-527
    • Okamoto, H.1    Voleti, B.2    Banasr, M.3    Sarhan, M.4    Duric, V.5
  • 20
    • 79959679248 scopus 로고    scopus 로고
    • A novel role of the WNTdishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression
    • Wilkinson MB, Dias C, Magida J, Mazei-Robison M, Lobo M, et al. 2011. A novel role of the WNTdishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression. J. Neurosci. 31:9084-92
    • (2011) J. Neurosci , vol.31 , pp. 9084-9092
    • Wilkinson, M.B.1    Dias, C.2    Magida, J.3    Mazei-Robison, M.4    Lobo, M.5
  • 21
    • 15144344289 scopus 로고    scopus 로고
    • Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress
    • Liu D, Diorio J, Tannenbaum B, Caldji C, Francis D, et al. 1997. Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. Science 277:1659-62
    • (1997) Science , vol.277 , pp. 1659-1662
    • Liu, D.1    Diorio, J.2    Tannenbaum, B.3    Caldji, C.4    Francis, D.5
  • 22
    • 36549070627 scopus 로고    scopus 로고
    • Stress-induced changes in primate prefrontal profiles of gene expression
    • Karssen AM, Her S, Li JZ, Patel PD, Meng F, et al. 2007. Stress-induced changes in primate prefrontal profiles of gene expression. Mol. Psychiatry 12:1089-102
    • (2007) Mol. Psychiatry , vol.12 , pp. 1089-1102
    • Karssen, A.M.1    Her, S.2    Li, J.Z.3    Patel, P.D.4    Meng, F.5
  • 23
    • 64949179797 scopus 로고    scopus 로고
    • Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal
    • Surget A, Wang Y, Leman S, Ibarguen-Vargas Y, Edgar N, et al. 2009. Corticolimbic transcriptome changes are state-dependent and region-specific in a rodent model of depression and of antidepressant reversal. Neuropsychopharmacology 34:1363-80
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1363-1380
    • Surget, A.1    Wang, Y.2    Leman, S.3    Ibarguen-Vargas, Y.4    Edgar, N.5
  • 24
    • 84855343964 scopus 로고    scopus 로고
    • Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models
    • Andrus BM, Blizinsky K, Vedell PT, Dennis K, Shukla PK, et al. 2012. Gene expression patterns in the hippocampus and amygdala of endogenous depression and chronic stress models. Mol. Psychiatry 17:49-61
    • (2012) Mol. Psychiatry , vol.17 , pp. 49-61
    • Andrus, B.M.1    Blizinsky, K.2    Vedell, P.T.3    Dennis, K.4    Shukla, P.K.5
  • 25
    • 79957492129 scopus 로고    scopus 로고
    • Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression
    • Bernard R, Kerman IA, Thompson RC, Jones EG, Bunney WE, et al. 2011. Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression. Mol. Psychiatry 16:634-46
    • (2011) Mol. Psychiatry , vol.16 , pp. 634-646
    • Bernard, R.1    Kerman, I.A.2    Thompson, R.C.3    Jones, E.G.4    Bunney, W.E.5
  • 28
    • 77956650793 scopus 로고    scopus 로고
    • Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness)
    • Le-Niculescu H, Patel SD, Niculescu AB. 2010. Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness). Curr. Opin. Pharmacol. 10:594-600
    • (2010) Curr. Opin. Pharmacol , vol.10 , pp. 594-600
    • Le-Niculescu, H.1    Patel, S.D.2    Niculescu, A.B.3
  • 29
    • 79959611025 scopus 로고    scopus 로고
    • Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression
    • Shelton RC,Claiborne J, Sidoryk-Wegrzynowicz M, Reddy R, Aschner M, et al. 2011. Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression. Mol. Psychiatry 16:751-62
    • (2011) Mol. Psychiatry , vol.16 , pp. 751-762
    • Shelton, R.C.1    Claiborne, J.2    Sidoryk-Wegrzynowicz, M.3    Reddy, R.4    Aschner, M.5
  • 30
    • 77952888646 scopus 로고    scopus 로고
    • FosB in brain reward circuits mediates resilience to stress and antidepressant responses
    • Vialou V, Robison AJ, LaPlant QC, Covington HE III, Dietz DM, et al. 2010. FosB in brain reward circuits mediates resilience to stress and antidepressant responses. Nat. Neurosci. 13:745-52
    • (2010) Nat. Neurosci , vol.13 , pp. 745-752
    • Vialou, V.1    Robison, A.J.2    Laplant, Q.C.3    Covington III, H.E.4    Dietz, D.M.5
  • 31
    • 78049274861 scopus 로고    scopus 로고
    • Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice
    • Elliott E, Ezra-Nevo G, Regev L, Neufeld-Cohen A, Chen A. 2010. Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice. Nat. Neurosci. 13:1351-3
    • (2010) Nat. Neurosci , vol.13 , pp. 1351-1353
    • Elliott, E.1    Ezra-Nevo, G.2    Regev, L.3    Neufeld-Cohen, A.4    Chen, A.5
  • 32
    • 77953812571 scopus 로고    scopus 로고
    • Epigenetics and gene expression
    • Gibney ER, Nolan CM. 2010. Epigenetics and gene expression. Heredity 105:4-13
    • (2010) Heredity , vol.105 , pp. 4-13
    • Gibney, E.R.1    Nolan, C.M.2
  • 34
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • Bird A. 2007. Perceptions of epigenetics. Nature 447:396-98
    • (2007) Nature , vol.447 , pp. 396-398
    • Bird, A.1
  • 37
    • 58149469090 scopus 로고    scopus 로고
    • Translational control of long-lasting synaptic plasticity and memory
    • Costa-Mattioli M, Sossin WS, Klann E, Sonenberg N. 2009. Translational control of long-lasting synaptic plasticity and memory. Neuron 61:10-26
    • (2009) Neuron , vol.61 , pp. 10-26
    • Costa-Mattioli, M.1    Sossin, W.S.2    Klann, E.3    Sonenberg, N.4
  • 39
    • 37349016848 scopus 로고    scopus 로고
    • Synaptic plasticity, memory and the hippocampus: A neural network approach to causality
    • Neves G, Cooke SF, BlissTV. 2008. Synaptic plasticity, memory and the hippocampus: a neural network approach to causality. Nat. Rev. Neurosci. 9:65-75
    • (2008) Nat. Rev. Neurosci , vol.9 , pp. 65-75
    • Neves, G.1    Cooke, S.F.2    Bliss, T.V.3
  • 40
    • 68649088591 scopus 로고    scopus 로고
    • Regulation of chromatin structure in memory formation
    • Roth TL, Sweatt JD. 2009. Regulation of chromatin structure in memory formation. Curr. Opin. Neurobiol. 19:336-42
    • (2009) Curr. Opin. Neurobiol , vol.19 , pp. 336-342
    • Roth, T.L.1    Sweatt, J.D.2
  • 41
    • 77953429462 scopus 로고    scopus 로고
    • Brain function and chromatin plasticity
    • Dulac C. 2010. Brain function and chromatin plasticity. Nature 465:728-35
    • (2010) Nature , vol.465 , pp. 728-735
    • Dulac, C.1
  • 42
    • 2942731425 scopus 로고    scopus 로고
    • CBP histone acetyltransferase activity is a critical component of memory consolidation
    • Korzus E, Rosenfeld MG, Mayford M. 2004. CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron 42:961-72
    • (2004) Neuron , vol.42 , pp. 961-972
    • Korzus, E.1    Rosenfeld, M.G.2    Mayford, M.3
  • 44
    • 13244276460 scopus 로고    scopus 로고
    • Epigeneticmechanisms in memory formation
    • Levenson JM, Sweatt JD. 2005. Epigeneticmechanisms in memory formation. Nat. Rev. Neurosci. 6:108-18
    • (2005) Nat. Rev. Neurosci , vol.6 , pp. 108-118
    • Levenson, J.M.1    Sweatt, J.D.2
  • 45
    • 33646784653 scopus 로고    scopus 로고
    • Maternal care associated with methylation of the estrogen receptor-α1b promoter and estrogen receptor-α expression in the medial preoptic area of female offspring
    • Champagne FA, Weaver IC, Diorio J, Dymov S, Szyf M, Meaney MJ. 2006. Maternal care associated with methylation of the estrogen receptor-α1b promoter and estrogen receptor-α expression in the medial preoptic area of female offspring. Endocrinology 147:2909-15
    • (2006) Endocrinology , vol.147 , pp. 2909-2915
    • Champagne, F.A.1    Weaver, I.C.2    Diorio, J.3    Dymov, S.4    Szyf, M.5    Meaney, M.J.6
  • 46
    • 79251578041 scopus 로고    scopus 로고
    • Distinct physiological and behavioural functions for parental alleles of imprinted Grb10
    • Garfield AS, Cowley M, Smith FM, Moorwood K, Stewart-Cox JE, et al. 2011. Distinct physiological and behavioural functions for parental alleles of imprinted Grb10. Nature 469:534-38
    • (2011) Nature , vol.469 , pp. 534-538
    • Garfield, A.S.1    Cowley, M.2    Smith, F.M.3    Moorwood, K.4    Stewart-Cox, J.E.5
  • 47
    • 74249105659 scopus 로고    scopus 로고
    • Essential role of the histone methyltransferase G9a in cocaine-induced plasticity
    • Maze I, Covington HE III, Dietz DM, LaPlant Q, Renthal W, et al. 2010. Essential role of the histone methyltransferase G9a in cocaine-induced plasticity. Science 327:213-16
    • (2010) Science , vol.327 , pp. 213-216
    • Maze, I.1    Covington Iii., H.E.2    Dietz, D.M.3    Laplant, Q.4    Renthal, W.5
  • 48
    • 80054827869 scopus 로고    scopus 로고
    • Transcriptional and epigenetic mechanisms of addiction
    • Robison AJ, NestlerEJ. 2011. Transcriptional and epigenetic mechanisms of addiction. Nat. Rev. Neurosci. 12:623-37
    • (2011) Nat. Rev. Neurosci , vol.12 , pp. 623-637
    • Robison, A.J.1    Nestler, E.J.2
  • 49
    • 77953510470 scopus 로고    scopus 로고
    • DNA methylation in vulnerability to post-traumatic stress in rats: Evidence for the role of the post-synaptic density protein Dlgap2
    • Chertkow-Deutsher Y, Cohen H, Klein E, Ben-Shachar D. 2010. DNA methylation in vulnerability to post-traumatic stress in rats: evidence for the role of the post-synaptic density protein Dlgap2. Int. J. Neuropsychopharmacol. 13:347-59
    • (2010) Int. J. Neuropsychopharmacol , vol.13 , pp. 347-359
    • Chertkow-Deutsher, Y.1    Cohen, H.2    Klein, E.3    Ben-Shachar, D.4
  • 50
    • 34249275353 scopus 로고    scopus 로고
    • Phenotypic plasticity and the epigenetics of human disease
    • Feinberg AP. 2007. Phenotypic plasticity and the epigenetics of human disease. Nature 447:433-40
    • (2007) Nature , vol.447 , pp. 433-440
    • Feinberg, A.P.1
  • 51
    • 34548319329 scopus 로고    scopus 로고
    • Molecular studies of major depressive disorder: The epigenetic perspective
    • Mill J, Petronis A. 2007. Molecular studies of major depressive disorder: the epigenetic perspective. Mol. Psychiatry 12:799-814
    • (2007) Mol. Psychiatry , vol.12 , pp. 799-814
    • Mill, J.1    Petronis, A.2
  • 52
    • 77649192193 scopus 로고    scopus 로고
    • Altered gene expression of histone deacetylases in mood disorder patients
    • Hobara T, Uchida S, Otsuki K, Matsubara T, Funato H, et al. 2009. Altered gene expression of histone deacetylases in mood disorder patients. J. Psychiatr. Res. 44:263-70
    • (2009) J. Psychiatr. Res , vol.44 , pp. 263-270
    • Hobara, T.1    Uchida, S.2    Otsuki, K.3    Matsubara, T.4    Funato, H.5
  • 53
    • 52949099506 scopus 로고    scopus 로고
    • GABAA receptor promoter hypermethylation in suicide brain: Implications for the involvement of epigenetic processes
    • Poulter MO, Du L, Weaver IC, Palkovits M, Faludi G, et al. 2008. GABAA receptor promoter hypermethylation in suicide brain: implications for the involvement of epigenetic processes. Biol. Psychiatry 64:645-52
    • (2008) Biol. Psychiatry , vol.64 , pp. 645-652
    • Poulter, M.O.1    Du, L.2    Weaver, I.C.3    Palkovits, M.4    Faludi, G.5
  • 57
    • 49349110160 scopus 로고    scopus 로고
    • The methyl-CpG-binding protein MeCP2 and neurological disease
    • Bird A. 2008. The methyl-CpG-binding protein MeCP2 and neurological disease. Biochem. Soc. Trans. 36:575-83
    • (2008) Biochem. Soc. Trans , vol.36 , pp. 575-583
    • Bird, A.1
  • 58
    • 2442684104 scopus 로고    scopus 로고
    • An evaluation of new criteria for CpG islands in the human genome as gene markers
    • Wang Y, Leung FC. 2004. An evaluation of new criteria for CpG islands in the human genome as gene markers. Bioinformatics 20:1170-77
    • (2004) Bioinformatics , vol.20 , pp. 1170-1177
    • Wang, Y.1    Leung, F.C.2
  • 59
  • 60
    • 34250188803 scopus 로고    scopus 로고
    • Genomic patterns of DNA methylation: Targets and function of an epigenetic mark
    • Weber M, Schubeler D. 2007. Genomic patterns of DNA methylation: targets and function of an epigenetic mark. Curr. Opin. Cell Biol. 19:273-80
    • (2007) Curr. Opin. Cell Biol , vol.19 , pp. 273-280
    • Weber, M.1    Schubeler, D.2
  • 62
    • 0033580326 scopus 로고    scopus 로고
    • A mammalian protein with specific demethylase activity for mCpG DNA
    • Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M. 1999. A mammalian protein with specific demethylase activity for mCpG DNA. Nature 397:579-83
    • (1999) Nature , vol.397 , pp. 579-583
    • Bhattacharya, S.K.1    Ramchandani, S.2    Cervoni, N.3    Szyf, M.4
  • 63
    • 33846933274 scopus 로고    scopus 로고
    • Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
    • Barreto G, Schafer A, Marhold J, Stach D, Swaminathan SK, et al. 2007. Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 445:671-75
    • (2007) Nature , vol.445 , pp. 671-675
    • Barreto, G.1    Schafer, A.2    Marhold, J.3    Stach, D.4    Swaminathan, S.K.5
  • 64
    • 60749094831 scopus 로고    scopus 로고
    • Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis
    • Ma DK, Jang MH, Guo JU, Kitabatake Y, Chang ML, et al. 2009. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 323:1074-77
    • (2009) Science , vol.323 , pp. 1074-1077
    • Ma, D.K.1    Jang, M.H.2    Guo, J.U.3    Kitabatake, Y.4    Chang, M.L.5
  • 65
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
    • Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, et al. 2009. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324:930-35
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1    Koh, K.P.2    Shen, Y.3    Pastor, W.A.4    Bandukwala, H.5
  • 66
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis S, Heintz N. 2009. The nuclear DNA base 5- hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324:929-30
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 67
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito S, Shen L, Dai Q, Wu SC, Collins LB, et al. 2011. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333:1300-3
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3    Wu, S.C.4    Collins, L.B.5
  • 68
    • 80052495940 scopus 로고    scopus 로고
    • Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
    • He YF, Li BZ, Li Z, Liu P,Wang Y, et al. 2011. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333:1303-7
    • (2011) Science , vol.333 , pp. 1303-1307
    • He, Y.F.1    Li, B.Z.2    Li, Z.3    Liu Pwang, Y.4
  • 69
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • Guo JU, Su Y, Zhong C, Ming GL, Song H. 2011. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145:423-34
    • (2011) Cell , vol.145 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 70
    • 82255192294 scopus 로고    scopus 로고
    • 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging
    • Szulwach KE, Li X, Li Y, Song CX, Wu H, et al. 2011. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nat. Neurosci. 14:1607-16
    • (2011) Nat. Neurosci , vol.14 , pp. 1607-1616
    • Szulwach, K.E.1    Li, X.2    Li, Y.3    Song, C.X.4    Wu, H.5
  • 71
    • 73449113904 scopus 로고    scopus 로고
    • Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
    • Hervouet E, Vallette FM, Cartron PF. 2009. Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation. Epigenetics 4:487-99
    • (2009) Epigenetics , vol.4 , pp. 487-499
    • Hervouet, E.1    Vallette, F.M.2    Cartron, P.F.3
  • 72
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir RE, Van den Veyver IB,Wan M, Tran CQ, Francke U, Zoghbi HY. 1999. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 23:185-88
    • (1999) Nat. Genet , vol.23 , pp. 185-188
    • Amir, R.E.1    Van Den Veyver Ibwan, M.2    Tran, C.Q.3    Francke, U.4    Zoghbi, H.Y.5
  • 73
    • 33847282970 scopus 로고    scopus 로고
    • Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation
    • Nan X, Hou J, Maclean A, Nasir J, Lafuente MJ, et al. 2007. Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation. Proc. Natl. Acad. Sci. USA 104:2709-14
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 2709-2714
    • Nan, X.1    Hou, J.2    MacLean, A.3    Nasir, J.4    Lafuente, M.J.5
  • 74
    • 0036384371 scopus 로고    scopus 로고
    • NIRF, a novel RING finger protein, is involved in cell-cycle regulation
    • Mori T, Li Y, Hata H, Ono K, Kochi H. 2002. NIRF, a novel RING finger protein, is involved in cell-cycle regulation. Biochem. Biophys. Res. Commun. 296:530-36
    • (2002) Biochem. Biophys. Res. Commun , vol.296 , pp. 530-536
    • Mori, T.1    Li, Y.2    Hata, H.3    Ono, K.4    Kochi, H.5
  • 75
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J, Zhou Y, Campbell SL, Le T, Li E, et al. 2010. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat. Neurosci. 13:423-30
    • (2010) Nat. Neurosci , vol.13 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3    Le Li T, E.4
  • 76
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • Miller CA, Sweatt JD. 2007. Covalent modification of DNA regulates memory formation. Neuron 53:857-69
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 78
    • 71749084889 scopus 로고    scopus 로고
    • The role of DNA methylation in the central nervous system and neuropsychiatric disorders
    • Feng J, Fan G. 2009. The role of DNA methylation in the central nervous system and neuropsychiatric disorders. Int. Rev. Neurobiol. 89:67-84
    • (2009) Int. Rev. Neurobiol , vol.89 , pp. 67-84
    • Feng, J.1    Fan, G.2
  • 79
    • 79958038559 scopus 로고    scopus 로고
    • Epigenetic mechanisms in cognition
    • Day JJ, Sweatt JD. 2011. Epigenetic mechanisms in cognition. Neuron 70:813-29
    • (2011) Neuron , vol.70 , pp. 813-829
    • Day, J.J.1    Sweatt, J.D.2
  • 80
    • 34249299791 scopus 로고    scopus 로고
    • The complex language of chromatin regulation during transcription
    • Berger SL. 2007. The complex language of chromatin regulation during transcription. Nature 447:407-12
    • (2007) Nature , vol.447 , pp. 407-412
    • Berger, S.L.1
  • 81
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl BD, Allis CD. 2000. The language of covalent histone modifications. Nature 403:41-45
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 82
    • 0034644473 scopus 로고    scopus 로고
    • Signaling to chromatin through histone modifications
    • Cheung P, Allis CD, Sassone-Corsi P. 2000. Signaling to chromatin through histone modifications. Cell 103:263-71
    • (2000) Cell , vol.103 , pp. 263-271
    • Cheung, P.1    Allis, C.D.2    Sassone-Corsi, P.3
  • 84
    • 0033214237 scopus 로고    scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • Kaeberlein M, McVey M, Guarente L. 1999. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 13:2570-80
    • (1999) Genes Dev , vol.13 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 85
    • 84455188711 scopus 로고    scopus 로고
    • Minireview:NAD+, a circadian metabolitewith an epigenetic twist
    • Sassone-Corsi P. 2012. Minireview:NAD+, a circadian metabolitewith an epigenetic twist. Endocrinology 153:1-5
    • (2012) Endocrinology , vol.153 , pp. 1-5
    • Sassone-Corsi, P.1
  • 86
    • 78649725166 scopus 로고    scopus 로고
    • Mammalian circadian clock and metabolism-the epigenetic link
    • Bellet MM, Sassone-Corsi P. 2010. Mammalian circadian clock and metabolism-the epigenetic link. J. Cell Sci. 123:3837-48
    • (2010) J. Cell Sci , vol.123 , pp. 3837-3848
    • Bellet, M.M.1    Sassone-Corsi, P.2
  • 87
    • 0035370439 scopus 로고    scopus 로고
    • Histone methylation versus histone acetylation: New insights into epigenetic regulation
    • Rice JC, Allis CD. 2001. Histone methylation versus histone acetylation: new insights into epigenetic regulation. Curr. Opin. Cell Biol. 13:263-73
    • (2001) Curr. Opin. Cell Biol , vol.13 , pp. 263-273
    • Rice, J.C.1    Allis, C.D.2
  • 88
    • 0037019333 scopus 로고    scopus 로고
    • Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
    • Sun ZW, Allis CD. 2002. Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418:104-8
    • (2002) Nature , vol.418 , pp. 104-108
    • Sun, Z.W.1    Allis, C.D.2
  • 89
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD. 2001. Translating the histone code. Science 293:1074-80
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 90
    • 77952581350 scopus 로고    scopus 로고
    • Long non-coding RNAs in nervous system function and disease
    • Qureshi IA, Mattick JS, Mehler MF. 2010. Long non-coding RNAs in nervous system function and disease. Brain Res. 1338:20-35
    • (2010) Brain Res , vol.1338 , pp. 20-35
    • Qureshi, I.A.1    Mattick, J.S.2    Mehler, M.F.3
  • 91
    • 80053045739 scopus 로고    scopus 로고
    • Molecular mechanisms of long noncoding RNAs
    • Wang KC, Chang HY. 2011. Molecular mechanisms of long noncoding RNAs. Mol. Cell 43:904-14
    • (2011) Mol. Cell , vol.43 , pp. 904-914
    • Wang, K.C.1    Chang, H.Y.2
  • 92
    • 79953858658 scopus 로고    scopus 로고
    • No-nonsense functions for long noncoding RNAs
    • Nagano T, Fraser P. 2011. No-nonsense functions for long noncoding RNAs. Cell 145:178-81
    • (2011) Cell , vol.145 , pp. 178-181
    • Nagano, T.1    Fraser, P.2
  • 93
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. 2009. MicroRNAs: target recognition and regulatory functions. Cell 136:215-33
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 94
    • 77956141295 scopus 로고    scopus 로고
    • MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212
    • Im HI, Hollander JA, Bali P, Kenny PJ. 2010. MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. Nat. Neurosci. 13:1120-27
    • (2010) Nat. Neurosci , vol.13 , pp. 1120-1127
    • Im, H.I.1    Hollander, J.A.2    Bali, P.3    Kenny, P.J.4
  • 95
    • 61849125304 scopus 로고    scopus 로고
    • Epigenetics: Heterochromatin meets RNAi
    • Djupedal I, Ekwall K. 2009. Epigenetics: heterochromatin meets RNAi. Cell Res. 19:282-95
    • (2009) Cell Res , vol.19 , pp. 282-295
    • Djupedal, I.1    Ekwall, K.2
  • 97
    • 33947310031 scopus 로고    scopus 로고
    • Environmental epigenomics and disease susceptibility
    • Jirtle RL, Skinner MK. 2007. Environmental epigenomics and disease susceptibility. Nat. Rev. Genet. 8:253-62
    • (2007) Nat. Rev. Genet , vol.8 , pp. 253-262
    • Jirtle, R.L.1    Skinner, M.K.2
  • 98
    • 21844434219 scopus 로고    scopus 로고
    • Environmental programming of stress responses through DNA methylation: Life at the interface between a dynamic environment and a fixed genome
    • Meaney MJ, Szyf M. 2005. Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome. Dialogues Clin. Neurosci. 7:103-23
    • (2005) Dialogues Clin. Neurosci , vol.7 , pp. 103-123
    • Meaney, M.J.1    Szyf, M.2
  • 100
    • 77952168294 scopus 로고    scopus 로고
    • Altered histone acetylation is associated with age-dependent memory impairment in mice
    • Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, et al. 2010. Altered histone acetylation is associated with age-dependent memory impairment in mice. Science 328:753-56
    • (2010) Science , vol.328 , pp. 753-756
    • Peleg, S.1    Sananbenesi, F.2    Zovoilis, A.3    Burkhardt, S.4    Bahari-Javan, S.5
  • 101
    • 77954855825 scopus 로고    scopus 로고
    • SIRT1 is essential for normal cognitive function and synaptic plasticity
    • Michan S, Li Y, Chou MM, Parrella E, Ge H, et al. 2010. SIRT1 is essential for normal cognitive function and synaptic plasticity. J. Neurosci. 30:9695-707
    • (2010) J. Neurosci , vol.30 , pp. 9695-9707
    • Michan, S.1    Li, Y.2    Chou, M.M.3    Parrella, E.4    Ge, H.5
  • 102
    • 52049126415 scopus 로고    scopus 로고
    • Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress
    • Fyffe SL, Neul JL, Samaco RC, Chao HT, Ben-Shachar S, et al. 2008. Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress. Neuron 59:947-58
    • (2008) Neuron , vol.59 , pp. 947-958
    • Fyffe, S.L.1    Neul, J.L.2    Samaco, R.C.3    Chao, H.T.4    Ben-Shachar, S.5
  • 103
    • 81755171960 scopus 로고    scopus 로고
    • Chronic stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat
    • Sterrenburg L, Gaszner B, Boerrigter J, Santbergen L, Bramini M, et al. 2011. Chronic stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat. PLoS ONE 6:e28128
    • (2011) PLoS ONE , vol.6
    • Sterrenburg, L.1    Gaszner, B.2    Boerrigter, J.3    Santbergen, L.4    Bramini, M.5
  • 104
    • 34548395111 scopus 로고    scopus 로고
    • The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior
    • Schmidt HD, Duman RS. 2007. The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behav. Pharmacol. 18:391-418
    • (2007) Behav. Pharmacol , vol.18 , pp. 391-418
    • Schmidt, H.D.1    Duman, R.S.2
  • 105
    • 79958765149 scopus 로고    scopus 로고
    • Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder
    • Roth TL, Zoladz PR, Sweatt JD, Diamond DM. 2011. Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder. J. Psychiatr. Res. 45:919-26
    • (2011) J. Psychiatr. Res , vol.45 , pp. 919-926
    • Roth, T.L.1    Zoladz, P.R.2    Sweatt, J.D.3    Diamond, D.M.4
  • 106
    • 0030318063 scopus 로고    scopus 로고
    • Stress, glucocorticoids, and damage to the nervous system: The current state of confusion
    • Sapolsky RM. 1996. Stress, glucocorticoids, and damage to the nervous system: the current state of confusion. Stress 1:1-19
    • (1996) Stress , vol.1 , pp. 1-19
    • Sapolsky, R.M.1
  • 107
    • 0030992982 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation
    • Gould E, McEwen BS, Tanapat P, Galea LA, Fuchs E. 1997. Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J. Neurosci. 17:2492-98
    • (1997) J. Neurosci , vol.17 , pp. 2492-2498
    • Gould, E.1    McEwen, B.S.2    Tanapat, P.3    Galea, L.A.4    Fuchs, E.5
  • 108
    • 78751689075 scopus 로고    scopus 로고
    • Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events
    • Uchida S, Hara K, Kobayashi A, Otsuki K, Yamagata H, et al. 2011. Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events. Neuron 69:359-72
    • (2011) Neuron , vol.69 , pp. 359-372
    • Uchida, S.1    Hara, K.2    Kobayashi, A.3    Otsuki, K.4    Yamagata, H.5
  • 109
    • 45849105557 scopus 로고    scopus 로고
    • MeCP2, a key contributor to neurological disease, activates and represses transcription
    • Chahrour M, Jung SY, ShawC,ZhouX,Wong ST, et al. 2008. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320:1224-29
    • (2008) Science , vol.320 , pp. 1224-1229
    • Chahrour, M.1    Jung, S.Y.2    Shaw, C.3    Zhou, X.4    Wong, S.T.5
  • 110
    • 84861077168 scopus 로고    scopus 로고
    • Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression
    • Melas PA, Rogdaki M, Lennartsson A, Bjork K, Qi H, et al. 2011. Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression. Int. J. Neuropsychopharmacol. 15:669-79
    • (2011) Int. J. Neuropsychopharmacol , vol.15 , pp. 669-679
    • Melas, P.A.1    Rogdaki, M.2    Lennartsson, A.3    Bjork, K.4    Qi, H.5
  • 111
    • 30344448578 scopus 로고    scopus 로고
    • Alterations in 5-HT1B receptor function by p11 in depression-like states
    • Svenningsson P, Chergui K, Rachleff I, Flajolet M, Zhang X, et al. 2006. Alterations in 5-HT1B receptor function by p11 in depression-like states. Science 311:77-80
    • (2006) Science , vol.311 , pp. 77-80
    • Svenningsson, P.1    Chergui, K.2    Rachleff, I.3    Flajolet, M.4    Zhang, X.5
  • 112
    • 41149136175 scopus 로고    scopus 로고
    • Serotonin receptor subtype and p11 mRNA expression in stress-relevant brain regions of suicide and control subjects
    • Anisman H, Du L, Palkovits M, Faludi G, Kovacs GG, et al. 2008. Serotonin receptor subtype and p11 mRNA expression in stress-relevant brain regions of suicide and control subjects. J. Psychiatry Neurosci. 33:131-41
    • (2008) J. Psychiatry Neurosci , vol.33 , pp. 131-141
    • Anisman, H.1    Du, L.2    Palkovits, M.3    Faludi, G.4    Kovacs, G.G.5
  • 113
    • 79960310830 scopus 로고    scopus 로고
    • Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample
    • Uddin M, Koenen KC, Aiello AE, Wildman DE, de los Santos R, Galea S. 2011. Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample. Psychol. Med. 41:997-1007
    • (2011) Psychol. Med , vol.41 , pp. 997-1007
    • Uddin, M.1    Koenen, K.C.2    Aiello, A.E.3    Wildman, D.E.4    De Los Santos, R.5    Galea, S.6
  • 114
    • 80054756091 scopus 로고    scopus 로고
    • Functional biomarkers of depression: Diagnosis, treatment, and pathophysiology
    • Schmidt HD, Shelton RC,Duman RS. 2011. Functional biomarkers of depression: diagnosis, treatment, and pathophysiology. Neuropsychopharmacology 36:2375-94
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2375-2394
    • Schmidt, H.D.1    Shelton Rcduman, R.S.2
  • 115
    • 77956139754 scopus 로고    scopus 로고
    • Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens
    • LaPlant Q, Vialou V, Covington HE III, Dumitriu D, Feng J, et al. 2010. Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. Nat. Neurosci. 13:1137-43
    • (2010) Nat. Neurosci , vol.13 , pp. 1137-1143
    • Laplant, Q.1    Vialou, V.2    Covington III, H.E.3    Dumitriu, D.4    Feng, J.5
  • 117
    • 78651484732 scopus 로고    scopus 로고
    • Repeated social defeat selectively increases-FosB expression and histoneH3acetylation in the infralimbicmedial prefrontal cortex
    • Hinwood M, Tynan RJ, Day TA,Walker FR. 2011. Repeated social defeat selectively increases-FosB expression and histoneH3acetylation in the infralimbicmedial prefrontal cortex. Cereb. Cortex 21:262-71
    • (2011) Cereb. Cortex , vol.21 , pp. 262-271
    • Hinwood, M.1    Tynan, R.J.2    Day Tawalker, F.R.3
  • 118
    • 79952697546 scopus 로고    scopus 로고
    • Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus
    • Hollis F, Duclot F, Gunjan A, Kabbaj M. 2011. Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus. Horm. Behav. 59:331-37
    • (2011) Horm. Behav , vol.59 , pp. 331-337
    • Hollis, F.1    Duclot, F.2    Gunjan, A.3    Kabbaj, M.4
  • 119
    • 77955581894 scopus 로고    scopus 로고
    • The effects of repeated social defeat on long-term depressive-like behavior and short-term histone modifications in the hippocampus in male Sprague-Dawley rats
    • Hollis F, Wang H, Dietz D, Gunjan A, Kabbaj M. 2010. The effects of repeated social defeat on long-term depressive-like behavior and short-term histone modifications in the hippocampus in male Sprague-Dawley rats. Psychopharmacology 211:69-77
    • (2010) Psychopharmacology , vol.211 , pp. 69-77
    • Hollis, F.1    Wang, H.2    Dietz, D.3    Gunjan, A.4    Kabbaj, M.5
  • 120
    • 33645357786 scopus 로고    scopus 로고
    • Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action
    • Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, Nestler EJ. 2006. Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat. Neurosci. 9:519-25
    • (2006) Nat. Neurosci , vol.9 , pp. 519-525
    • Tsankova, N.M.1    Berton, O.2    Renthal, W.3    Kumar, A.4    Neve, R.L.5    Nestler, E.J.6
  • 121
    • 34250161829 scopus 로고    scopus 로고
    • Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse
    • Schroeder FA, Lin CL, Crusio WE, Akbarian S. 2007. Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse. Biol. Psychiatry 62:55-64
    • (2007) Biol. Psychiatry , vol.62 , pp. 55-64
    • Schroeder, F.A.1    Lin, C.L.2    Crusio, W.E.3    Akbarian, S.4
  • 123
    • 67349243029 scopus 로고    scopus 로고
    • Effects of the histone deacetylase inhibitor sodium butyrate in models of depression and anxiety
    • Gundersen BB, Blendy JA. 2009. Effects of the histone deacetylase inhibitor sodium butyrate in models of depression and anxiety. Neuropharmacology 57:67-74
    • (2009) Neuropharmacology , vol.57 , pp. 67-74
    • Gundersen, B.B.1    Blendy, J.A.2
  • 124
    • 3042589127 scopus 로고    scopus 로고
    • Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures
    • Tsankova NM, Kumar A, Nestler EJ. 2004. Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J. Neurosci. 24:5603-10
    • (2004) J. Neurosci , vol.24 , pp. 5603-5610
    • Tsankova, N.M.1    Kumar, A.2    Nestler, E.J.3
  • 125
    • 80051908751 scopus 로고    scopus 로고
    • A role for repressive histone methylation in cocaine-induced vulnerability to stress
    • Covington HE III, Maze I, Sun H, Bomze HM, DeMaio KD, et al. 2011. A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron 71:656-70
    • (2011) Neuron , vol.71 , pp. 656-670
    • Covington Iii., H.E.1    Maze, I.2    Sun, H.3    Bomze, H.M.4    Demaio, K.D.5
  • 127
    • 67449168166 scopus 로고    scopus 로고
    • Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models
    • Wilkinson MB, Xiao G, Kumar A, LaPlant Q, Renthal W, et al. 2009. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models. J. Neurosci. 29:7820-32
    • (2009) J. Neurosci , vol.29 , pp. 7820-7832
    • Wilkinson, M.B.1    Xiao, G.2    Kumar, A.3    Laplant, Q.4    Renthal, W.5
  • 128
    • 58849095405 scopus 로고    scopus 로고
    • CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits
    • Wallace DL, Han MH, Graham DL, Green TA, Vialou V, et al. 2009. CREB regulation of nucleus accumbens excitability mediates social isolation-induced behavioral deficits. Nat. Neurosci. 12:200-9
    • (2009) Nat. Neurosci , vol.12 , pp. 200-209
    • Wallace, D.L.1    Han, M.H.2    Graham, D.L.3    Green, T.A.4    Vialou, V.5
  • 129
    • 77953069207 scopus 로고    scopus 로고
    • Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B
    • Jiang Y, Jakovcevski M, Bharadwaj R, Connor C, Schroeder FA, et al. 2010. Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B. J. Neurosci. 30:7152-67
    • (2010) J. Neurosci , vol.30 , pp. 7152-7167
    • Jiang, Y.1    Jakovcevski, M.2    Bharadwaj, R.3    Connor, C.4    Schroeder, F.A.5
  • 130
    • 79251512930 scopus 로고    scopus 로고
    • Hippocampus, amygdala, and stress: Interacting systems that affect susceptibility to addiction
    • Belujon P, Grace AA. 2011. Hippocampus, amygdala, and stress: interacting systems that affect susceptibility to addiction. Ann. N. Y. Acad. Sci. 1216:114-21
    • (2011) Ann. N. Y. Acad. Sci , vol.1216 , pp. 114-121
    • Belujon, P.1    Grace, A.A.2
  • 131
    • 57049118276 scopus 로고    scopus 로고
    • KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress
    • Jakobsson J, Cordero MI, Bisaz R, Groner AC, Busskamp V, et al. 2008. KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress. Neuron 60:818-31
    • (2008) Neuron , vol.60 , pp. 818-831
    • Jakobsson, J.1    Cordero, M.I.2    Bisaz, R.3    Groner, A.C.4    Busskamp, V.5
  • 132
    • 77956677763 scopus 로고    scopus 로고
    • MiR-16 targets the serotonin transporter: A new facet for adaptive responses to antidepressants
    • Baudry A, Mouillet-Richard S, Schneider B, Launay JM, Kellermann O. 2010. miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants. Science 329:1537-41
    • (2010) Science , vol.329 , pp. 1537-1541
    • Baudry, A.1    Mouillet-Richard, S.2    Schneider, B.3    Launay, J.M.4    Kellermann, O.5
  • 133
    • 84455169414 scopus 로고    scopus 로고
    • SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive
    • Libert S, Pointer K, Bell EL, Das A, Cohen DE, et al. 2011. SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive. Cell 147:1459-72
    • (2011) Cell , vol.147 , pp. 1459-1472
    • Libert, S.1    Pointer, K.2    Bell, E.L.3    Das, A.4    Cohen, D.E.5
  • 134
    • 77956185062 scopus 로고    scopus 로고
    • A novel pathway regulates memory and plasticity via SIRT1 and miR-134
    • Gao J, Wang WY, Mao YW, Graff J, Guan JS, et al. 2010. A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature 466:1105-9
    • (2010) Nature , vol.466 , pp. 1105-1109
    • Gao, J.1    Wang, W.Y.2    Mao, Y.W.3    Graff, J.4    Guan, J.S.5
  • 135
    • 0035354550 scopus 로고    scopus 로고
    • Effects of early stress on brain structure and function: Implications for understanding the relationship between child maltreatment and depression
    • Kaufman J, Charney D. 2001. Effects of early stress on brain structure and function: implications for understanding the relationship between child maltreatment and depression. Dev. Psychopathol. 13:451-71
    • (2001) Dev. Psychopathol , vol.13 , pp. 451-471
    • Kaufman, J.1    Charney, D.2
  • 136
    • 67349157695 scopus 로고    scopus 로고
    • Effects of stress throughout the lifespan on the brain, behaviour and cognition
    • Lupien SJ, McEwen BS, Gunnar MR, Heim C. 2009. Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat. Rev. Neurosci. 10:434-45
    • (2009) Nat. Rev. Neurosci , vol.10 , pp. 434-445
    • Lupien, S.J.1    McEwen, B.S.2    Gunnar, M.R.3    Heim, C.4
  • 137
    • 0023268460 scopus 로고
    • Doabused children become abusive parents?
    • Kaufman J,Zigler E. 1987.Doabused children become abusive parents? Am. J.Orthopsychiatry 57:186-92
    • (1987) Am J.Orthopsychiatry , vol.57 , pp. 186-192
    • Kaufman, J.1    Zigler, E.2
  • 138
    • 33847189237 scopus 로고    scopus 로고
    • Generalized anxiety disorder and depression: Childhood risk factors in a birth cohort followed to age 32
    • Moffitt TE, Caspi A, Harrington H, Milne BJ, Melchior M, et al. 2007. Generalized anxiety disorder and depression: childhood risk factors in a birth cohort followed to age 32. Psychol. Med. 37:441-52
    • (2007) Psychol. Med , vol.37 , pp. 441-452
    • Moffitt, T.E.1    Caspi, A.2    Harrington, H.3    Milne, B.J.4    Melchior, M.5
  • 140
    • 84872942417 scopus 로고    scopus 로고
    • Epigenetic vestiges of early developmental adversity: Childhood stress exposure and DNA methylation in adolescence
    • In press doi: 10.1111/j.1467-8624.2011.01641.x
    • Essex MJ, Thomas Boyce W, Hertzman C, Lam LL, Armstrong JM, et al. 2011. Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescence. Child Dev. In press, doi: 10.1111/j.1467-8624.2011.01641.x
    • (2011) Child Dev
    • Essex, M.J.1    Thomas Boyce, W.2    Hertzman, C.3    Lam, L.L.4    Armstrong, J.M.5
  • 142
    • 0034928759 scopus 로고    scopus 로고
    • Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations
    • Meaney MJ. 2001. Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annu. Rev. Neurosci. 24:1161-92
    • (2001) Annu. Rev. Neurosci , vol.24 , pp. 1161-1192
    • Meaney, M.J.1
  • 143
    • 33845342923 scopus 로고    scopus 로고
    • Effects of repeatedmaternal separation on anxiety-and depression-related phenotypes in different mouse strains
    • Millstein RA,Holmes A. 2007. Effects of repeatedmaternal separation on anxiety-and depression-related phenotypes in different mouse strains. Neurosci. Biobehav. Rev. 31:3-17
    • (2007) Neurosci. Biobehav. Rev , vol.31 , pp. 3-17
    • Millstein, R.A.1    Holmes, A.2
  • 144
    • 70549104872 scopus 로고    scopus 로고
    • Dynamic DNA methylation programs persistent adverse effects of early-life stress
    • Murgatroyd C, Patchev AV, Wu Y, Micale V, Bockmuhl Y, et al. 2009. Dynamic DNA methylation programs persistent adverse effects of early-life stress. Nat. Neurosci. 12:1559-66
    • (2009) Nat. Neurosci , vol.12 , pp. 1559-1566
    • Murgatroyd, C.1    Patchev, A.V.2    Wu, Y.3    Micale, V.4    Bockmuhl, Y.5
  • 145
    • 33846529087 scopus 로고    scopus 로고
    • The hypothalamic-pituitaryadrenal axis response to stress in mice lacking functional vasopressin V1b receptors
    • Lolait SJ, Stewart LQ, Jessop DS, Young WS III, O'Carroll AM. 2007. The hypothalamic-pituitaryadrenal axis response to stress in mice lacking functional vasopressin V1b receptors. Endocrinology 148:849-56
    • (2007) Endocrinology , vol.148 , pp. 849-856
    • Lolait, S.J.1    Stewart, L.Q.2    Jessop, D.S.3    Young III, W.S.4    O'Carroll, A.M.5
  • 146
    • 63449085750 scopus 로고    scopus 로고
    • Lasting epigenetic influence of early-life adversity on the BDNF gene
    • Roth TL, Lubin FD, Funk AJ, Sweatt JD. 2009. Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol. Psychiatry 65:760-69
    • (2009) Biol. Psychiatry , vol.65 , pp. 760-769
    • Roth, T.L.1    Lubin, F.D.2    Funk, A.J.3    Sweatt, J.D.4
  • 147
    • 79952700004 scopus 로고    scopus 로고
    • Epigenetic marking of the BDNF gene by early-life adverse experiences
    • Roth TL, Sweatt JD. 2011. Epigenetic marking of the BDNF gene by early-life adverse experiences. Horm. Behav. 59:315-20
    • (2011) Horm. Behav , vol.59 , pp. 315-320
    • Roth, T.L.1    Sweatt, J.D.2
  • 148
    • 77954224132 scopus 로고    scopus 로고
    • Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns
    • Edwards JR, O'Donnell AH, Rollins RA, Peckham HE, Lee C, et al. 2010. Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns. Genome Res. 20:972-80
    • (2010) Genome Res , vol.20 , pp. 972-980
    • Edwards, J.R.1    O'Donnell, A.H.2    Rollins, R.A.3    Peckham, H.E.4    Lee, C.5
  • 149
    • 81955164243 scopus 로고    scopus 로고
    • Early life stress triggers sustained changes in histone deacetylase expression and histone H4 modifications that alter responsiveness to adolescent antidepressant treatment
    • Levine A, Worrell TR, Zimnisky R, Schmauss C. 2012. Early life stress triggers sustained changes in histone deacetylase expression and histone H4 modifications that alter responsiveness to adolescent antidepressant treatment. Neurobiol. Dis. 45:488-98
    • (2012) Neurobiol. Dis , vol.45 , pp. 488-498
    • Levine, A.1    Worrell, T.R.2    Zimnisky, R.3    Schmauss, C.4
  • 150
    • 77449083293 scopus 로고    scopus 로고
    • Epigenetics and the environmental regulation of the genome and its function
    • Zhang TY, Meaney MJ. 2010. Epigenetics and the environmental regulation of the genome and its function. Annu. Rev. Psychol. 61:439-66
    • (2010) Annu. Rev. Psychol , vol.61 , pp. 439-466
    • Zhang, T.Y.1    Meaney, M.J.2
  • 152
    • 33847093463 scopus 로고    scopus 로고
    • The transcription factor nerve growth factor-inducible protein A mediates epigenetic programming: Altering epigenetic marks by immediate-early genes
    • Weaver IC, D'Alessio AC, Brown SE, Hellstrom IC, Dymov S, et al. 2007. The transcription factor nerve growth factor-inducible protein A mediates epigenetic programming: altering epigenetic marks by immediate-early genes. J. Neurosci. 27:1756-68
    • (2007) J. Neurosci , vol.27 , pp. 1756-1768
    • Weaver, I.C.1    D'Alessio, A.C.2    Brown, S.E.3    Hellstrom, I.C.4    Dymov, S.5
  • 153
    • 79957642777 scopus 로고    scopus 로고
    • The HSP90 molecular chaperone cycle regulates cyclical transcriptional dynamics of the glucocorticoid receptor and its coregulatory molecules CBP/p300 during ultradian ligand treatment
    • Conway-Campbell BL, George CL, Pooley JR, Knight DM, Norman MR, et al. 2011. The HSP90 molecular chaperone cycle regulates cyclical transcriptional dynamics of the glucocorticoid receptor and its coregulatory molecules CBP/p300 during ultradian ligand treatment. Mol. Endocrinol. 25:944-54
    • (2011) Mol. Endocrinol , vol.25 , pp. 944-954
    • Conway-Campbell, B.L.1    George, C.L.2    Pooley, J.R.3    Knight, D.M.4    Norman, M.R.5
  • 154
    • 41449114497 scopus 로고    scopus 로고
    • Structural basis of site-specific histone recognition by the bromodomains of human coactivatorsPCAFand CBP/p300
    • Zeng L, Zhang Q, Gerona-Navarro G, Moshkina N, Zhou MM. 2008. Structural basis of site-specific histone recognition by the bromodomains of human coactivatorsPCAFand CBP/p300. Structure 16:643-52
    • (2008) Structure , vol.16 , pp. 643-652
    • Zeng, L.1    Zhang, Q.2    Gerona-Navarro, G.3    Moshkina, N.4    Zhou, M.M.5
  • 155
    • 28044436691 scopus 로고    scopus 로고
    • Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: Altering epigenetic marking later in life
    • Weaver IC, Champagne FA, Brown SE, Dymov S, Sharma S, et al. 2005. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J. Neurosci. 25:11045-54
    • (2005) J. Neurosci , vol.25 , pp. 11045-11054
    • Weaver, I.C.1    Champagne, F.A.2    Brown, S.E.3    Dymov, S.4    Sharma, S.5
  • 156
    • 69249219123 scopus 로고    scopus 로고
    • Maternal care determines rapid effects of stress mediators on synaptic plasticity in adult rat hippocampal dentate gyrus
    • Bagot RC, van Hasselt FN, Champagne DL, Meaney MJ, Krugers HJ, Jöels M. 2009. Maternal care determines rapid effects of stress mediators on synaptic plasticity in adult rat hippocampal dentate gyrus. Neurobiol. Learn. Mem. 92:292-300
    • (2009) Neurobiol. Learn. Mem , vol.92 , pp. 292-300
    • Bagot, R.C.1    Van Hasselt, F.N.2    Champagne, D.L.3    Meaney, M.J.4    Krugers, H.J.5    Jöels, M.6
  • 157
    • 43049156118 scopus 로고    scopus 로고
    • Epigenetic mechanisms and the transgenerational effects of maternal care
    • Champagne FA. 2008. Epigenetic mechanisms and the transgenerational effects of maternal care. Front. Neuroendocrinol. 29:386-97
    • (2008) Front. Neuroendocrinol , vol.29 , pp. 386-397
    • Champagne, F.A.1
  • 158
    • 60749105468 scopus 로고    scopus 로고
    • Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
    • McGowan PO, Sasaki A, D'Alessio AC, Dymov S, Labonte B, et al. 2009. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat. Neurosci. 12:342-48
    • (2009) Nat. Neurosci , vol.12 , pp. 342-348
    • McGowan, P.O.1    Sasaki, A.2    D'Alessio, A.C.3    Dymov, S.4    Labonte, B.5
  • 159
    • 38349002755 scopus 로고    scopus 로고
    • Transgenerational effects of social environment on variations in maternal care and behavioral response to novelty
    • Champagne FA, Meaney MJ. 2007. Transgenerational effects of social environment on variations in maternal care and behavioral response to novelty. Behav. Neurosci. 121:1353-63
    • (2007) Behav. Neurosci , vol.121 , pp. 1353-1363
    • Champagne, F.A.1    Meaney, M.J.2
  • 160
  • 161
    • 33644763991 scopus 로고    scopus 로고
    • Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood
    • Weaver IC, Meaney MJ, Szyf M. 2006. Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc. Natl. Acad. Sci. USA 103:3480-85
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 3480-3485
    • Weaver, I.C.1    Meaney, M.J.2    Szyf, M.3
  • 162
    • 47749133462 scopus 로고    scopus 로고
    • Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain
    • McGowan PO, Sasaki A, Huang TC, Unterberger A, Suderman M, et al. 2008. Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS ONE 3:e2085
    • (2008) PLoS ONE , vol.3
    • McGowan, P.O.1    Sasaki, A.2    Huang, T.C.3    Unterberger, A.4    Suderman, M.5
  • 163
    • 34547683888 scopus 로고    scopus 로고
    • Effects of prenatal restraint stress on the hypothalamus-pituitaryadrenal axis and related behavioural and neurobiological alterations
    • Maccari S, Morley-Fletcher S. 2007. Effects of prenatal restraint stress on the hypothalamus-pituitaryadrenal axis and related behavioural and neurobiological alterations. Psychoneuroendocrinology 32(Suppl. 1):S10-15
    • (2007) Psychoneuroendocrinology , vol.32 , Issue.SUPPL. 1
    • MacCari, S.1    Morley-Fletcher, S.2
  • 164
    • 45849128326 scopus 로고    scopus 로고
    • The long-term behavioural consequences of prenatal stress
    • Weinstock M. 2008. The long-term behavioural consequences of prenatal stress. Neurosci. Biobehav. Rev. 32:1073-86
    • (2008) Neurosci. Biobehav. Rev , vol.32 , pp. 1073-1086
    • Weinstock, M.1
  • 165
    • 77953181772 scopus 로고    scopus 로고
    • Intrauterine factors as determinants of depressive disorder
    • Weinstock M. 2010. Intrauterine factors as determinants of depressive disorder. Isr. J. Psychiatry Relat. Sci. 47:36-45
    • (2010) Isr. J. Psychiatry Relat. Sci , vol.47 , pp. 36-45
    • Weinstock, M.1
  • 166
    • 47149100122 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
    • Oberlander TF, Weinberg J, Papsdorf M, Grunau R, Misri S, Devlin AM. 2008. Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 3:97-106
    • (2008) Epigenetics , vol.3 , pp. 97-106
    • Oberlander, T.F.1    Weinberg, J.2    Papsdorf, M.3    Grunau, R.4    Misri, S.5    Devlin, A.M.6
  • 167
    • 36249006451 scopus 로고    scopus 로고
    • Transgenerational transmission of cortisol and PTSD risk
    • Yehuda R, Bierer LM. 2008. Transgenerational transmission of cortisol and PTSD risk. Prog. Brain Res. 167:121-35
    • (2008) Prog. Brain Res , vol.167 , pp. 121-135
    • Yehuda, R.1    Bierer, L.M.2
  • 168
    • 34548450682 scopus 로고    scopus 로고
    • Parental posttraumatic stress disorder as a vulnerability factor for low cortisol trait in offspring of Holocaust survivors
    • Yehuda R, Teicher MH, Seckl JR, Grossman RA, Morris A, Bierer LM. 2007. Parental posttraumatic stress disorder as a vulnerability factor for low cortisol trait in offspring of Holocaust survivors. Arch. Gen. Psychiatry 64:1040-48
    • (2007) Arch. Gen. Psychiatry , vol.64 , pp. 1040-1048
    • Yehuda, R.1    Teicher, M.H.2    Seckl, J.R.3    Grossman, R.A.4    Morris, A.5    Bierer, L.M.6
  • 169
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R, Bird A. 2003. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33(Suppl.):245-54
    • (2003) Nat. Genet , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 170
    • 16444381345 scopus 로고    scopus 로고
    • Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
    • Feng J, Chang H, Li E, Fan G. 2005. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J. Neurosci. Res 79:734-46
    • (2005) J. Neurosci. Res , vol.79 , pp. 734-746
    • Feng, J.1    Chang, H.2    Li, E.3    Fan, G.4
  • 171
    • 0029963657 scopus 로고    scopus 로고
    • Synaptic activity and the construction of cortical circuits
    • Katz LC, Shatz CJ. 1996. Synaptic activity and the construction of cortical circuits. Science 274:1133-38
    • (1996) Science , vol.274 , pp. 1133-1138
    • Katz, L.C.1    Shatz, C.J.2
  • 173
    • 77955654186 scopus 로고    scopus 로고
    • Epigenetic transmission of the impact of early stress across generations
    • Franklin TB, Russig H,Weiss IC, Graff J, Linder N, et al. 2010. Epigenetic transmission of the impact of early stress across generations. Biol. Psychiatry 68:408-15
    • (2010) Biol. Psychiatry , vol.68 , pp. 408-415
    • Franklin, T.B.1    Russig, H.2    Weiss, I.C.3    Graff, J.4    Linder, N.5
  • 174
    • 54049086269 scopus 로고    scopus 로고
    • Sex-specific programming of offspring emotionality after stress early in pregnancy
    • Mueller BR, Bale TL. 2008. Sex-specific programming of offspring emotionality after stress early in pregnancy. J. Neurosci. 28:9055-65
    • (2008) J. Neurosci , vol.28 , pp. 9055-9065
    • Mueller, B.R.1    Bale, T.L.2
  • 175
    • 34247255851 scopus 로고    scopus 로고
    • Early prenatal stress impact on coping strategies and learning performance is sex dependent
    • Mueller BR, Bale TL. 2007. Early prenatal stress impact on coping strategies and learning performance is sex dependent. Physiol. Behav. 91:55-65
    • (2007) Physiol. Behav , vol.91 , pp. 55-65
    • Mueller, B.R.1    Bale, T.L.2
  • 176
    • 80051724610 scopus 로고    scopus 로고
    • Early prenatal stress epigenetically programs dysmasculinization in secondgeneration offspring via the paternal lineage
    • Morgan CP, Bale TL. 2011. Early prenatal stress epigenetically programs dysmasculinization in secondgeneration offspring via the paternal lineage. J. Neurosci. 31:11748-55
    • (2011) J. Neurosci , vol.31 , pp. 11748-11755
    • Morgan, C.P.1    Bale, T.L.2
  • 178
    • 79952697165 scopus 로고    scopus 로고
    • Epigenetics and the origins of paternal effects
    • Curley JP, Mashoodh R, Champagne FA. 2011. Epigenetics and the origins of paternal effects. Horm. Behav. 59:306-14
    • (2011) Horm. Behav , vol.59 , pp. 306-314
    • Curley, J.P.1    Mashoodh, R.2    Champagne, F.A.3
  • 179
    • 33645389729 scopus 로고    scopus 로고
    • Consequences of paternal cocaine exposure in mice
    • He F, Lidow IA, Lidow MS. 2006. Consequences of paternal cocaine exposure in mice. Neurotoxicol. Teratol. 28:198-209
    • (2006) Neurotoxicol. Teratol , vol.28 , pp. 198-209
    • He, F.1    Lidow, I.A.2    Lidow, M.S.3
  • 180
    • 70350313230 scopus 로고    scopus 로고
    • Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice
    • Dunn GA, Bale TL. 2009. Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice. Endocrinology 150:4999-5009
    • (2009) Endocrinology , vol.150 , pp. 4999-5009
    • Dunn, G.A.1    Bale, T.L.2
  • 181
    • 79956301666 scopus 로고    scopus 로고
    • Maternal high-fat diet effects on third-generation female body size via the paternal lineage
    • Dunn GA, Bale TL. 2011. Maternal high-fat diet effects on third-generation female body size via the paternal lineage. Endocrinology 152:2228-36
    • (2011) Endocrinology , vol.152 , pp. 2228-2236
    • Dunn, G.A.1    Bale, T.L.2
  • 182
    • 20344385787 scopus 로고    scopus 로고
    • Epigenetic transgenerational actions of endocrine disruptors and male fertility
    • Anway MD, Cupp AS,Uzumcu M, SkinnerMK. 2005. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 308:1466-69
    • (2005) Science , vol.308 , pp. 1466-1469
    • Anway, M.D.1    Cupp Asuzumcu, M.2    Skinner, M.K.3
  • 183
    • 56749170156 scopus 로고    scopus 로고
    • Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior
    • Skinner MK, Anway MD, Savenkova MI, Gore AC, Crews D. 2008. Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior. PLoS ONE 3:e3745
    • (2008) PLoS ONE , vol.3
    • Skinner, M.K.1    Anway, M.D.2    Savenkova, M.I.3    Gore, A.C.4    Crews, D.5
  • 184
    • 75149150268 scopus 로고    scopus 로고
    • Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm
    • Stouder C, Paoloni-Giacobino A. 2010. Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm. Reproduction 139:373-79
    • (2010) Reproduction , vol.139 , pp. 373-379
    • Stouder, C.1    Paoloni-Giacobino, A.2
  • 185
    • 77953292127 scopus 로고    scopus 로고
    • Repressive and active histone methylationmark distinct promoters in human and mouse spermatozoa
    • Brykczynska U, Hisano M, Erkek S, Ramos L, Oakeley EJ, et al. 2010. Repressive and active histone methylationmark distinct promoters in human and mouse spermatozoa. Nat. Struct. Mol. Biol. 17:679-87
    • (2010) Nat. Struct. Mol. Biol , vol.17 , pp. 679-687
    • Brykczynska, U.1    Hisano, M.2    Erkek, S.3    Ramos, L.4    Oakeley, E.J.5
  • 186
    • 78650061153 scopus 로고    scopus 로고
    • Transgenerational epigenetic inheritance: More questions than answers
    • Daxinger L,Whitelaw E. 2010. Transgenerational epigenetic inheritance: more questions than answers. Genome Res. 20:1623-28
    • (2010) Genome Res , vol.20 , pp. 1623-1628
    • Daxinger Lwhitelaw, E.1
  • 187
    • 77952885756 scopus 로고    scopus 로고
    • Epigenetic inheritance in mammals: Evidence for the impact of adverse environmental effects
    • Franklin TB,Mansuy IM. 2010. Epigenetic inheritance in mammals: evidence for the impact of adverse environmental effects. Neurobiol. Dis. 39:61-65
    • (2010) Neurobiol. Dis , vol.39 , pp. 61-65
    • Franklin, T.B.1    Mansuy, I.M.2
  • 188
  • 189
    • 79952108547 scopus 로고    scopus 로고
    • Non-Mendelian epigenetic heredity: Gametic RNAs as epigenetic regulators and transgenerational signals
    • Cuzin F, Rassoulzadegan M. 2010. Non-Mendelian epigenetic heredity: gametic RNAs as epigenetic regulators and transgenerational signals. Essays Biochem. 48:101-6
    • (2010) Essays Biochem , vol.48 , pp. 101-106
    • Cuzin, F.1    Rassoulzadegan, M.2
  • 190
    • 77953516812 scopus 로고    scopus 로고
    • The making of an organ: RNA mediated developmental controls in mice
    • Rassoulzadegan M, Cuzin F. 2010. The making of an organ: RNA mediated developmental controls in mice. Organogenesis 6:33-36
    • (2010) Organogenesis , vol.6 , pp. 33-36
    • Rassoulzadegan, M.1    Cuzin, F.2
  • 191
    • 78049414227 scopus 로고    scopus 로고
    • Epigenetic reprogramming in plant and animal development
    • Feng S, Jacobsen SE, Reik W. 2010. Epigenetic reprogramming in plant and animal development. Science 330:622-27
    • (2010) Science , vol.330 , pp. 622-627
    • Feng, S.1    Jacobsen, S.E.2    Reik, W.3
  • 192
    • 1942471150 scopus 로고    scopus 로고
    • Epigenetic regulation of mammalian genomic imprinting
    • Delaval K, Feil R. 2004. Epigenetic regulation of mammalian genomic imprinting. Curr. Opin. Genet. Dev. 14:188-95
    • (2004) Curr. Opin. Genet. Dev , vol.14 , pp. 188-195
    • Delaval, K.1    Feil, R.2
  • 193
    • 0035234557 scopus 로고    scopus 로고
    • Genomic imprinting: Parental influence on the genome
    • ReikW,Walter J. 2001. Genomic imprinting: parental influence on the genome. Nat. Rev. Genet. 2:21-32
    • (2001) Nat. Rev. Genet , vol.2 , pp. 21-32
    • Reik, W.1    Walter, J.2
  • 196
    • 33645453109 scopus 로고    scopus 로고
    • Regulation of growth and metabolism by imprinted genes
    • Smith FM, Garfield AS, Ward A. 2006. Regulation of growth and metabolism by imprinted genes. Cytogenet. Genome Res. 113:279-91
    • (2006) Cytogenet. Genome Res , vol.113 , pp. 279-291
    • Smith, F.M.1    Garfield, A.S.2    Ward, A.3
  • 199
    • 77957911410 scopus 로고    scopus 로고
    • Allele-specific methylation in the human genome: Implications for genetic studies of complex disease
    • Meaburn EL, Schalkwyk LC, Mill J. 2010. Allele-specific methylation in the human genome: implications for genetic studies of complex disease. Epigenetics 5:578-82
    • (2010) Epigenetics , vol.5 , pp. 578-582
    • Meaburn, E.L.1    Schalkwyk, L.C.2    Mill, J.3
  • 200
    • 77955285002 scopus 로고    scopus 로고
    • Sex-specific parent-of-origin allelic expression in the mouse brain
    • Gregg C, Zhang J, Butler JE, Haig D, Dulac C. 2010. Sex-specific parent-of-origin allelic expression in the mouse brain. Science 329:682-85
    • (2010) Science , vol.329 , pp. 682-685
    • Gregg, C.1    Zhang, J.2    Butler, J.E.3    Haig, D.4    Dulac, C.5
  • 201
    • 77955299096 scopus 로고    scopus 로고
    • High-resolution analysis of parentof-origin allelic expression in the mouse brain
    • Gregg C, Zhang J, Weissbourd B, Luo S, Schroth GP, et al. 2010. High-resolution analysis of parentof-origin allelic expression in the mouse brain. Science 329:643-48
    • (2010) Science , vol.329 , pp. 643-648
    • Gregg, C.1    Zhang, J.2    Weissbourd, B.3    Luo, S.4    Schroth, G.P.5
  • 202
    • 78649459828 scopus 로고    scopus 로고
    • Targets and dynamics of promoter DNA methylation during early mouse development
    • Borgel J, Guibert S, Li Y, Chiba H, Schubeler D, et al. 2010. Targets and dynamics of promoter DNA methylation during early mouse development. Nat. Genet. 42:1093-100
    • (2010) Nat. Genet , vol.42 , pp. 1093-1100
    • Borgel, J.1    Guibert, S.2    Li, Y.3    Chiba, H.4    Schubeler, D.5
  • 203
    • 77952715009 scopus 로고    scopus 로고
    • Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex
    • Cheung I, Shulha HP, Jiang Y, Matevossian A, Wang J, et al. 2010. Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex. Proc. Natl. Acad. Sci. USA 107:8824-29
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 8824-8829
    • Cheung, I.1    Shulha, H.P.2    Jiang, Y.3    Matevossian, A.4    Wang, J.5
  • 204
    • 79955583542 scopus 로고    scopus 로고
    • Mapping and analysis of chromatin state dynamics in nine human cell types
    • Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, et al. 2011. Mapping and analysis of chromatin state dynamics in nine human cell types. Nature 473:43-49
    • (2011) Nature , vol.473 , pp. 43-49
    • Ernst, J.1    Kheradpour, P.2    Mikkelsen, T.S.3    Shoresh, N.4    Ward, L.D.5
  • 205
    • 70349448571 scopus 로고    scopus 로고
    • Environmental influence on L1 retrotransposons in the adult hippocampus
    • Muotri AR, Zhao C,Marchetto MC, Gage FH. 2009. Environmental influence on L1 retrotransposons in the adult hippocampus. Hippocampus 19:1002-7
    • (2009) Hippocampus , vol.19 , pp. 1002-1007
    • Muotri, A.R.1    Zhao, C.2    Marchetto, M.C.3    Gage, F.H.4
  • 207
    • 69449086642 scopus 로고    scopus 로고
    • Wnt-mediated activation ofNeuroD1 and retro-elements during adult neurogenesis
    • Kuwabara T, Hsieh J,Muotri A, YeoG,Warashina M, et al. 2009. Wnt-mediated activation ofNeuroD1 and retro-elements during adult neurogenesis. Nat. Neurosci. 12:1097-105
    • (2009) Nat. Neurosci , vol.12 , pp. 1097-1105
    • Kuwabara, T.1    Hsieh, J.2    Muotri, A.3    Yeo, G.4    Warashina, M.5
  • 208
    • 79952582606 scopus 로고    scopus 로고
    • Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens
    • Maze I, Feng J, Wilkinson MB, Sun H, Shen L, Nestler EJ. 2011. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proc. Natl. Acad. Sci. USA 108:3035-40
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 3035-3040
    • Maze, I.1    Feng, J.2    Wilkinson, M.B.3    Sun, H.4    Shen, L.5    Nestler, E.J.6
  • 210
    • 79956308473 scopus 로고    scopus 로고
    • Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
    • Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R, et al. 2011. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 473:394-97
    • (2011) Nature , vol.473 , pp. 394-397
    • Pastor, W.A.1    Pape, U.J.2    Huang, Y.3    Henderson, H.R.4    Lister, R.5
  • 211
    • 84872247366 scopus 로고    scopus 로고
    • Chromatin-based treatments for affective disorders-insight or utopia
    • ed. JF Cryan, BE Leonard Basel, Switz.: Karger
    • Covington HI, Berton O. 2010. Chromatin-based treatments for affective disorders-insight or utopia. In Depression: From Psychopathology to Pharmacotherapy, ed. JF Cryan, BE Leonard, pp. 182-98. Basel, Switz.: Karger
    • (2010) Depression: From Psychopathology to Pharmacotherapy , pp. 182-198
    • Covington, H.I.1    Berton, O.2


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